CN107367622A - Full-automatic blood type analysis system - Google Patents
Full-automatic blood type analysis system Download PDFInfo
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- CN107367622A CN107367622A CN201710506644.1A CN201710506644A CN107367622A CN 107367622 A CN107367622 A CN 107367622A CN 201710506644 A CN201710506644 A CN 201710506644A CN 107367622 A CN107367622 A CN 107367622A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00148—Test cards, e.g. Biomerieux or McDonnel multiwell test cards
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00742—Type of codes
- G01N2035/00752—Type of codes bar codes
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Abstract
The invention discloses a kind of full-automatic blood type analysis system, including host computer, middle-position machine, the cartridge for depositing micro-column gel card, manipulator subsystem, micro-column gel card recognition subsystem, puncture subsystem, sample-adding subsystem, centrifugation subsystem and image acquisition and processing subsystem;The host computer judges subsystem including data storage subsystem, display subsystem and graphical analysis;Instruction is communicated to middle-position machine by the host computer, corresponding subsystem execute instruction task is distributed to after middle-position machine parses, and implementing result is fed back into host computer by middle-position machine.The analysis system of the present invention can reuse to the micro-column gel card for having remaining hole position, avoid wasting remaining hole position, effectively increase the service efficiency of micro-column gel card, reduce experimental cost;The automatic classification of micro-column gel card is collected according to the result of identification in experimentation, avoids the maloperation easily occurred during manual sort, avoids the identification work of repetition, improves the efficiency of analysis experiment.
Description
Technical field
The invention belongs to technical field of medical instruments, is related to a kind of full-automatic blood type analysis system.
Background technology
Clinical blood detection at present generally using cassette detection method simple to operate, that result is clear and definite, stable, mainly utilizes
The product that biochemistry gel filtration technology and centrifugation technique and the reaction of immunology antigen and antibody specific are combined, passes through regulation
The concentration of gel controls the size in gel gap, its gap is allowed free red blood cell by so that free
Red blood cell separates with the red blood cell of aggregation.Cleaning Principle is:When antigen, antibody response, aggegation occurs for haemocyte, during centrifugation, coagulates
Glomeration can not be by gel gap, and stays in the upper strata of gel pore, then is positive.It can lead to during UA haemocyte centrifugation
Cross gel gap, and be deposited on the bottom of gel pore, then it is negative.
For example, full-automatic blood type instrument is namely based on microtrabeculae Agglutination Test, coordinate with applicable micro-column gel detection card
Use, available for the detection of people ABO/RhD blood group antigens, the detection of ABO/RhD blood groups qualitative detection, Rh blood groupings, anti-human ball egg
White cross matching detection, the detection of antihuman globulin irregular antibody, antihuman globulin reagent classification (IgG/C3d sensitization) detection
Purpose detects.
Full-automatic blood type analysis is loaded-(incubation)-centrifugation-acquisition image-automatic decision result etc. including scanning-puncturing-
Step.In existing analysis system, because micro-column gel card is usually disposable, no matter several holes have been used in current experiment
Position, if also have remaining hole position not use, this experiment is completed, and the micro-column gel card just will not reuse, so sweeping
When retouching micro-column gel card and be identified, only identify that its tests type information, without identifying its hole position information.Such as
This, the service efficiency of micro-column gel card is extremely low, and often some experiment classifications need only to use one or two of micro-column gel card
Hole position (micro-column gel card that blood type analysis uses has 6 hole positions, as shown in Figure 1), remaining four or five hole positions just directly waste
Fall.
The content of the invention
To solve the above problems, the present invention proposes a kind of full-automatic blood type analysis system, can be to there is remaining hole position
Micro-column gel card is reused, and is avoided the waste of micro-column gel card hole position and reagent, is saved inspection cost.
In order to achieve the above object, technical scheme provided by the invention is:Full-automatic blood type analysis system, including it is upper
Machine, middle-position machine, deposit the cartridge of micro-column gel card, manipulator subsystem, micro-column gel card recognition subsystem, puncture subsystem,
It is loaded subsystem, centrifugation subsystem and image acquisition and processing subsystem;The manipulator subsystem, micro-column gel card identification subsystem
Unite, puncture subsystem, sample-adding subsystem, centrifugation subsystem and image acquisition and processing subsystem communicated respectively with middle-position machine;It is described
Host computer judges subsystem including data storage subsystem, display subsystem and graphical analysis;The host computer will be instructed and passed on
To middle-position machine, corresponding subsystem execute instruction task is distributed to after middle-position machine parses, and implementing result is passed through into middle-position machine
Feed back to host computer.
Preferably, the manipulator subsystem is used to carry micro-column gel card;The micro-column gel card recognition subsystem pair
The bar code of micro-column gel card is scanned, and the bar code information of scanning is uploaded into host computer by middle-position machine, then from host computer
Data storage subsystem read the type of micro-column gel card corresponding to the bar code and hole position information, identification judges bar code correspondence
Micro-column gel card whether meet experiment demand;It is described to puncture subsystem according to experiment demand to being identified through the micro-column gel card
The corresponding hole site that subsystem identifier closes the micro-column gel card of requirement of experiment is punctured;The subsystem that is loaded is by reality to be detected
The sample tested is added to through in the corresponding hole site for puncturing the micro-column gel card that subsystem punctures;The centrifugation subsystem pair adds
Sample and the micro-column gel card progress centrifugal treating for reacting completion.Described image acquisition process subsystem is to after centrifugal treating
Experimental result in micro-column gel card corresponding hole site carries out IMAQ and processing, and the image information that will be gathered and handle passes through
Middle-position machine is uploaded to host computer;Described image analysis judges the image letter that subsystem uploads to described image acquisition process subsystem
Breath carries out analysis judgement, draws experimental result, and experimental result data storage is arrived into the data storage subsystem, and by described
Display subsystem exports experimental result and the type and hole position information of micro-column gel card used.
Preferably, the micro-column gel card recognition subsystem includes barcode scanning module, type identification judge module and hole position knowledge
Other judge module;The barcode scanning module is scanned to the bar code of micro-column gel card, and the bar code information of scanning is passed through into middle position
Machine is uploaded to host computer;The type identification judge module and hole position identify judge module again respectively from the data storage of host computer
Subsystem reads the type of micro-column gel card corresponding to the bar code and hole position information, and identification judges micro-column gel corresponding to the bar code
Whether card meets experiment demand.
Preferably, the type identification judge module reads the barcode scanning module scans from the data storage subsystem
The type information of micro-column gel card corresponding to bar code, it is compared with the type needed for testing, judges the class of the micro-column gel card
Whether type meets experiment demand;If the type of the micro-column gel card meets experiment demand, the hole position identification is notified to judge
Module further reads the hole position information of micro-column gel card corresponding to the bar code, judges the remaining untapped hole of the micro-column gel
Enough whether this experiment uses for position.
Preferably, the sample-adding subsystem includes sample needle control module, sample reagent memory module and cleaning module;Institute
Sample needle control module is stated to be mixed according to the instruction of middle-position machine control sample needle absorption sample and reagent, draw sample mixing
Liquid be added to by the corresponding hole site for puncturing the micro-column gel card that subsystem punctures and draw cleaning fluid carry out sample needle it is clear
Wash;The movement or rotation of the sample reagent memory module stored samples and reagent, control sample and reagent.
Preferably, the data storage subsystem includes micro-column gel card database and experimental result data storehouse;It is described micro-
The data of post gel cards database purchase include the type and hole position information of micro-column gel card;The experimental result data library storage
Data include the collection of described image acquisition process subsystem experimental result original image and processing after image, and image
Analysis judges the experimental result data that subsystem analysis judges.
Preferably, described image analysis judges that subsystem includes parameter preset database and result compares analysis module, institute
Stating parameter preset database includes the canonical parameter of different experiments result of various experiment types;The result compares analysis module
Various experiment knots by the image that described image acquisition process subsystem uploads to corresponding experiment type in parameter preset database
Judgement is analyzed in fruit canonical parameter, draws this experimental result, and the image of this experiment and result data are transmitted
To the data storage subsystem and the display subsystem.
Preferably, the type information of the micro-column gel card includes bar code, title, abbreviation and total hole position number;The hole
Position information includes lot number, the term of validity, sequence number and each hole position service condition.
Preferably, the cartridge of the storage micro-column gel card includes rough-in box, screens out box and recycling box;The rough-in box is deposited
Put micro-column gel card to be selected;It is described screen out box storage through the micro-column gel card recognition subsystem identification be judged as being unsatisfactory for
The micro-column gel card of this experiment demand;The recycling box deposits hole position all using the micro-column gel card finished;It is described it is complete from
Dynamic blood type analysis system also collects subsystem including micro-column gel card, to completing experiment and being carried out through image acquisition and processing subsystem
Micro-column gel card after the collection of experimental result image carries out classification and collected, and the micro-column gel card of not remaining hole position is collected
In the recycling box, the also remaining reusable micro-column gel card of hole position is collected in rough-in box.
Preferably, the full-automatic blood type analysis system also includes incubating subsystem, pair has added sample and needs incubate instead
The sample in micro-column gel card that should be tested is incubated.
Beneficial effects of the present invention:
The full-automatic blood type analysis system of the present invention, (1) increased micro-column gel card recognition subsystem, can not only scan knowledge
The type information of other micro-column gel card, moreover it is possible to the hole position use information of micro-column gel card is identified, and according to this experiment to hole position
The demand of quantity, Selective type and remaining hole position meet that the micro-column gel card of experiment demand carries out sample-adding test experience, can be to having
The micro-column gel card of remaining hole position is reused, and until all hole position uses finish, avoids wasting once unspent
Micro-column gel card residue hole position, effectively increase the service efficiency of micro-column gel card;(2) micro-column gel card collect subsystem can be
By the micro-column gel card used, classification collects automatically after experiment, avoids the maloperation easily occurred during manual sort;(3)
The cartridge that micro-column gel card is deposited in analysis system is divided into rough-in box, screens out box and recycling box, ensure that manipulator subsystem
It will not be grabbed when capturing micro-column gel card and have been previously identified as the micro-column gel card for being unsatisfactory for this requirement of experiment, avoided
Micro-column gel card recognition subsystem carries out repeating identification work, improves the efficiency of analysis experiment.
Brief description of the drawings
The present invention is further described with reference to the accompanying drawings and examples.
Fig. 1 is the schematic diagram of micro-column gel card;
Fig. 2 is the schematic diagram of full-automatic blood type analysis system embodiment 1 of the present invention;
Fig. 3 is the schematic diagram of full-automatic blood type analysis system embodiment 2 of the present invention;
Fig. 4 is micro-column gel card recognition subsystem structural representation of the present invention;
Fig. 5 is present invention sample-adding subsystem structure schematic diagram;
Fig. 6 is data storage subsystem structural representation of the present invention;
Fig. 7 is that graphical analysis of the present invention judges subsystem structure schematic diagram;
Fig. 8 is experiment type codes match information schematic diagram in database;
The record information schematic diagram of micro-column gel card hole position service condition in Fig. 9 databases.
Embodiment
In conjunction with the accompanying drawings, the present invention is further explained in detail.These accompanying drawings are simplified schematic diagram, only with
Illustration illustrates the basic structure of the present invention, therefore it only shows the composition relevant with the present invention.
Embodiment 1
As shown in Fig. 2 be the present invention full-automatic blood type analysis system, including host computer, middle-position machine, storage micro-column gel
The cartridge of card, manipulator subsystem, micro-column gel card recognition subsystem, puncture subsystem, sample-adding subsystem, centrifugation subsystem and
Image acquisition and processing subsystem.Wherein, manipulator subsystem, micro-column gel card recognition subsystem, puncture subsystem, sample-adding subsystem
System, centrifugation subsystem and image acquisition and processing subsystem communicate with middle-position machine respectively.Host computer then include data storage subsystem,
Display subsystem and graphical analysis judge subsystem.During work, instruction is communicated to middle-position machine by host computer, after middle-position machine parses
Corresponding subsystem execute instruction task is distributed to, and implementing result is fed back into host computer by middle-position machine.
Specifically, manipulator subsystem carries micro-column gel card according to the instruction of middle-position machine, it is included in cartridge, micro-column gel
Card recognition subsystem, puncture subsystem, sample-adding subsystem, centrifugation subsystem and image acquisition subsystem between carry microtrabeculae coagulate
Glue card, a carrying action is often completed, performance is just fed back into middle-position machine.After middle-position machine is connected to corresponding completion instruction,
Instruction is assigned to the corresponding subsystem of slave computer.
When micro-column gel card is transported to the relevant position of micro-column gel card recognition subsystem by manipulator subsystem from cartridge
Afterwards, the signal carried and completed is fed back to middle-position machine, after middle-position machine receives the signal, notice micro-column gel card recognition subsystem is swept
The bar code of corresponding micro-column gel card is retouched, completes identification.Micro-column gel card recognition subsystem coagulates according to the instruction of middle-position machine to microtrabeculae
The bar code of glue card is scanned, and the bar code information of scanning is uploaded into host computer, then the data from host computer by middle-position machine
Storage subsystem reads the type of micro-column gel card corresponding to the bar code and hole position information, and identification judges microtrabeculae corresponding to the bar code
Whether gel cards meet experiment demand.Specifically, as shown in figure 4, the micro-column gel card recognition subsystem includes barcode scanning module, class
Type identifies judge module and hole position identification judge module.Wherein, barcode scanning module is scanned to the bar code of micro-column gel card, and will
The bar code information of scanning is uploaded to host computer by middle-position machine, while middle-position machine notification type identifies judge module from host computer
Data storage subsystem reads the type information of micro-column gel card corresponding to the bar code, as shown in figure 8, including including bar code, name
Title (type), abbreviation and total hole position number etc., judge whether the type of micro-column gel card corresponding to the bar code meets this experiment
The requirement of type.If the type mismatch of the micro-column gel card closes this requirement of experiment, middle-position machine, middle-position machine notice are fed back to
Manipulator subsystem fetches the card, carries other micro-column gel card again and carries out barcode scanning identification judgement, meets class until getting
The micro-column gel card of type requirement.When type identification judge module recognizes the micro-column gel card for meeting experiment type requirement, then
Notice hole position identification judge module continues to read micro-column gel card corresponding to the bar code from the data storage subsystem of host computer
Hole position information, as shown in figure 9, including lot number, the term of validity, sequence number and each hole position service condition, judge micro- corresponding to the bar code
Whether post gel cards also have untapped hole position, and whether untapped hole position quantity meets this requirement of experiment.If hole position number
Amount is unsatisfactory for this requirement of experiment, then feeds back to middle-position machine, and middle-position machine notice manipulator subsystem is fetched the card, carried again another
Outer micro-column gel card carries out barcode scanning identification and judged, the identification for repeating above-mentioned type and hole position information judges, until getting class
Type and hole position are satisfied by the micro-column gel card of this requirement of experiment, then notify the middle-position machine micro-column gel card to meet that experiment will
Ask.The micro-column gel card recognition subsystem, can not only scanning recognition micro-column gel card type information, moreover it is possible to identify micro-column gel
The hole position use information of card, and experiment need are met according to the demand of this experiment device to hole bit quantity, Selective type and remaining hole position
The micro-column gel card asked carries out sample-adding test experience, the micro-column gel card that have remaining hole position can be reused, Zhi Daosuo
There is hole position use to finish, avoid wasting once unspent micro-column gel card residue hole position, effectively increase micro-column gel card
Service efficiency.
When middle-position machine receives the letter that micro-column gel card recognition subsystem recognizes the micro-column gel card for meeting requirement of experiment
After number, the satisfactory micro-column gel card is transported to the pierce region for puncturing subsystem by notice manipulator subsystem, leads to
Know that puncturing subsystem performs the action punctured.Subsystem is punctured according to experiment demand to the above-mentioned micro-column gel for meeting requirement of experiment
The corresponding hole site of card is punctured.After completion punctures, the notification signal for puncturing completion is sent to middle-position machine, middle-position machine is connected to the letter
After number, notice host computer updates the data the hole position usage record of micro-column gel card storage subsystem Nei, while notifies sample-adding
System is loaded.
After sample-adding subsystem receives the instruction of middle-position machine, the sample of experiment to be detected is added to and punctured through puncturing subsystem
Micro-column gel card corresponding hole site in.Specifically, as shown in figure 5, sample-adding subsystem includes sample needle control module, sample tries
Agent memory module and cleaning module.Wherein, sample needle control module can control sample needle to draw sample according to the instruction of middle-position machine
Sample mixed liquor is mixed and drawn with reagent to be added in the corresponding hole site of the micro-column gel card punctured, is also inhaled
Cleaning fluid is taken to carry out sample needle cleaning.Sample reagent memory module stored samples and reagent, control the movement of sample and reagent, turn
Dynamic sample reagent mixed liquor shakes up etc..Cleaning module can clean to sample needle, make sample needle is repeatable to utilize.Add
After the completion of sample, the notification signal of sample-adding completion is sent to middle-position machine.
After middle-position machine receives sample-adding completion signal, the micro-column gel card is transported to centrifugation by notice manipulator subsystem
On the position of system, and the reaction time according to needed for experiment type, after the completion of judging that reaction is basic, notice centrifugation subsystem pair
Add sample and react the micro-column gel card progress centrifugal treating of completion.After completing centrifugally operated, send and centrifuged to middle-position machine
Into notification signal.
After middle-position machine receives centrifugation completion signal, notify manipulator subsystem by the micro-column gel of the completion centrifugally operated
Card is transported on the position of image acquisition and processing subsystem, while notifies image acquisition and processing subsystem to after centrifugal treating
Experimental result in micro-column gel card corresponding hole site carries out IMAQ and processing, and the image information that will be gathered and handle passes through
Middle-position machine is uploaded to host computer.Meanwhile middle-position machine notice manipulator subsystem will complete the micro-column gel card of result images collection
Carry go back to the relevant position of cartridge.
The graphical analysis of host computer judges that the image information that subsystem uploads to above-mentioned image acquisition and processing subsystem is carried out
Analysis judges, draws experimental result, experimental result data storage is arrived into data storage subsystem, and export by display subsystem
The type and hole position information of experimental result and micro-column gel card used.Specifically, as shown in fig. 7, graphical analysis judges subsystem
Analysis module is compared including parameter preset database and result, parameter preset database includes the different experiments of various experiment types
As a result canonical parameter, the foundation as interpretation experimental result.And result compares analysis module by above-mentioned image acquisition and processing
The image that system uploads is carried out to score to the various experimental result canonical parameters of corresponding experiment type in parameter preset database
Analysis judges, draws this experimental result, and send the image of this experiment and result data to data storage subsystem and show
Show subsystem.Wherein, data storage subsystem includes micro-column gel card database and experimental result data storehouse, as shown in Figure 6.It is micro-
The data of post gel cards database purchase include the type and hole position information of micro-column gel card;The number of experimental result data library storage
According to the image after the experimental result original image and processing gathered including above-mentioned image acquisition and processing subsystem, and graphical analysis
Judge the experimental result data that subsystem analysis judges.Display subsystem can export this experiment type and hole position demand, read
Figure after the type and hole position information of the micro-column gel card taken, the original image of image acquisition and processing subsystem collection and processing
The type of the micro-column gel card and the hole position information of renewal after the completion of picture, and final experimental result data and experiment.
Embodiment 2
The embodiment adds incubation subsystem, as shown in Figure 3 on the basis of embodiment 1.Some experiment types,
, it is necessary to carry out incubation reaction after sample-adding.Middle-position machine requires that notice incubates subsystem and opened after the completion of sample-adding according to experiment type
Begin to incubate, and incubative time is set according to requirement of experiment.After the completion of incubation, manipulator subsystem is reinformed by the micro-column gel card
It is transported to centrifugation subsystem and carries out centrifugally operated.
Embodiment 3
The embodiment adds micro-column gel card and collects subsystem, and will deposit microtrabeculae on the basis of embodiment 1 or 2
The cartridge of gel cards is arranged to include rough-in box, screen out box and the classification of recycling box collects cartridge.Wherein, rough-in box storage is to be selected
Micro-column gel card;Box storage is screened out to be judged as being unsatisfactory for this experiment demand through the identification of micro-column gel card recognition subsystem
Micro-column gel card;And recycling box then deposits hole position all using the micro-column gel card finished.
Micro-column gel card collects subsystem to completing experiment and carrying out experimental result image through image acquisition and processing subsystem
Micro-column gel card after collection carries out classification and collected.After the completion of experiment, micro-column gel card collects subsystem from data storage
Subsystem reads the hole position information of the micro-column gel card, according to the hole position service condition of the micro-column gel card, judges that the microtrabeculae coagulates
Whether the hole position of glue card has exhausted, without remaining hole position.If it is confirmed that the micro-column gel card does not have remaining hole position, then lead to
Middle-position machine notice manipulator subsystem is crossed to collect the micro-column gel card in the recycling box of above-mentioned cartridge;If micro-column gel card
Also remaining hole position can reuse, then notify manipulator subsystem that the micro-column gel card is collected into cartridge by middle-position machine
In rough-in box, selected for follow-up experiment.
The micro-column gel card collects subsystem and can collected the automatic classification of the micro-column gel card used after experiment, keeps away
The maloperation easily occurred during manual sort is exempted from.Cartridge is divided into rough-in box, screens out box and recycling box, to different service conditions
Micro-column gel card carry out classification and collect, ensure that manipulator subsystem will not be grabbed when capturing micro-column gel card by
It is identified as being unsatisfactory for the micro-column gel card of this requirement of experiment, avoids micro-column gel card recognition subsystem and carry out repeating identification work
Make, improve the efficiency of analysis experiment.
It is complete by above-mentioned description, relevant staff using the above-mentioned desirable embodiment according to the present invention as enlightenment
Various changes and amendments can be carried out without departing from the scope of the technological thought of the present invention' entirely.The technology of this invention
Property scope is not limited to the content on specification, it is necessary to determines its technical scope according to right.
Claims (10)
1. full-automatic blood type analysis system, it is characterised in that:Including host computer, middle-position machine, the cartridge for depositing micro-column gel card, machine
Tool hand subsystem, micro-column gel card recognition subsystem, puncture at subsystem, sample-adding subsystem, centrifugation subsystem and IMAQ
Manage subsystem;The manipulator subsystem, micro-column gel card recognition subsystem, puncture subsystem, sample-adding subsystem, centrifugation subsystem
System and image acquisition and processing subsystem communicate with middle-position machine respectively;The host computer includes data storage subsystem, display subsystem
System and graphical analysis judge subsystem;Instruction is communicated to middle-position machine by the host computer, is distributed to after middle-position machine parses corresponding
Subsystem execute instruction task, and implementing result is fed back into host computer by middle-position machine.
2. full-automatic blood type analysis system according to claim 1, it is characterised in that:
The manipulator subsystem is used to carry micro-column gel card;
The micro-column gel card recognition subsystem is scanned to the bar code of micro-column gel card, and the bar code information of scanning is passed through
Middle-position machine is uploaded to host computer, then the type of micro-column gel card corresponding to the bar code is read from the data storage subsystem of host computer
With hole position information, identification judges whether micro-column gel card meets experiment demand corresponding to the bar code;
It is described to puncture subsystem according to experiment demand to meeting requirement of experiment through micro-column gel card recognition subsystem identification
The corresponding hole site of micro-column gel card is punctured;
The sample of experiment to be detected is added to through the phase for puncturing the micro-column gel card that subsystem punctures by the sample-adding subsystem
Answer in hole position;
The centrifugation subsystem pair has added sample and has reacted the micro-column gel card progress centrifugal treating of completion;
Described image acquisition process subsystem is carried out to the experimental result in the micro-column gel card corresponding hole site after centrifugal treating
IMAQ and processing, and the image information that will be gathered and handle is uploaded to host computer by middle-position machine;
Described image analysis judges that the image information that subsystem uploads to described image acquisition process subsystem carries out analysis judgement,
Experimental result is drawn, the data storage subsystem is arrived into experimental result data storage, and export by the display subsystem
The type and hole position information of experimental result and micro-column gel card used.
3. full-automatic blood type analysis system according to claim 2, it is characterised in that:The micro-column gel card identifies subsystem
System includes barcode scanning module, type identification judge module and hole position identification judge module;The barcode scanning module is to micro-column gel card
Bar code is scanned, and the bar code information of scanning is uploaded into host computer by middle-position machine;The type identification judge module and
Hole position identification judge module reads the class of micro-column gel card corresponding to the bar code from the data storage subsystem of host computer respectively again
Type and hole position information, identification judge whether micro-column gel card meets experiment demand corresponding to the bar code.
4. full-automatic blood type analysis system according to claim 3, it is characterised in that:The type identification judge module from
The data storage subsystem reads the type information of micro-column gel card corresponding to the bar code of the barcode scanning module scans, with experiment
Required type is compared, and judges whether the type of the micro-column gel card meets experiment demand;If the micro-column gel card
Type meets experiment demand, then notifies the hole position identification judge module further to read micro-column gel card corresponding to the bar code
Hole position information, judge whether enough this experiment uses the remaining untapped hole position of the micro-column gel.
5. full-automatic blood type analysis system according to claim 2, it is characterised in that:The sample-adding subsystem includes sample-adding
Pin control module, sample reagent memory module and cleaning module;The sample needle control module controls according to the instruction of middle-position machine
Sample needle draws sample and reagent and is mixed, draws sample mixed liquor and be added to by the micro-column gel for puncturing subsystem and puncturing
In the corresponding hole site of card and absorption cleaning fluid carries out sample needle cleaning;The sample reagent memory module stored samples and examination
The movement or rotation of agent, control sample and reagent.
6. full-automatic blood type analysis system according to claim 2, it is characterised in that:The data storage subsystem includes
Micro-column gel card database and experimental result data storehouse;The data of the micro-column gel card database purchase include micro-column gel card
Type and hole position information;The data of the experimental result data library storage include the collection of described image acquisition process subsystem
Image after experimental result original image and processing, and graphical analysis judge the experimental result data that subsystem analysis judges.
7. full-automatic blood type analysis system according to claim 2, it is characterised in that:Described image analysis judges subsystem
Analysis module is compared including parameter preset database and result, the parameter preset database includes the difference of various experiment types
The canonical parameter of experimental result;The result compare image that described image acquisition process subsystem uploads by analysis module with advance
Judgement is analyzed in the various experimental result canonical parameters of corresponding experiment type in setting parameter database, draws this experiment
As a result, and by the image of this experiment and result data send the data storage subsystem and the display subsystem to.
8. according to the full-automatic blood type analysis system described in claim any one of 2-7, it is characterised in that:The micro-column gel card
Type information include bar code, title, abbreviation and total hole position number;The hole position information include lot number, the term of validity, sequence number and
Each hole position service condition.
9. the full-automatic blood type analysis system according to claim 1-7, it is characterised in that:The storage micro-column gel card
Cartridge includes rough-in box, screens out box and recycling box;The rough-in box deposits micro-column gel card to be selected;It is described to screen out box storage
It is judged as being unsatisfactory for the micro-column gel card of this experiment demand through micro-column gel card recognition subsystem identification;The recycling box
Hole position is deposited all using the micro-column gel card finished;The full-automatic blood type analysis system also collects son including micro-column gel card
System, carried out to completing experiment and the micro-column gel card after experimental result image collection being carried out through image acquisition and processing subsystem
Classification is collected, and the micro-column gel card of not remaining hole position is collected in the recycling box, and also remaining hole position can be made again
Micro-column gel card is collected in rough-in box.
10. according to the full-automatic blood type analysis system described in claim any one of 1-7, it is characterised in that:The full-automatic blood
Type analysis system also includes incubating subsystem, pair has added sample and has needed the sample in the micro-column gel card that incubation reaction tests to enter
Row incubates.
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