CN107362450A - Transcranial magnetic stimulation circuit, stimulator and its magnetic field impulse generation method - Google Patents

Transcranial magnetic stimulation circuit, stimulator and its magnetic field impulse generation method Download PDF

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Publication number
CN107362450A
CN107362450A CN201710649506.9A CN201710649506A CN107362450A CN 107362450 A CN107362450 A CN 107362450A CN 201710649506 A CN201710649506 A CN 201710649506A CN 107362450 A CN107362450 A CN 107362450A
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CN
China
Prior art keywords
inductance coil
magnetic stimulation
magnetic field
transcranial magnetic
circuit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710649506.9A
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Chinese (zh)
Inventor
谢飞跃
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Shenzhen Physiological Science And Technology Co Ltd
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Shenzhen Physiological Science And Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Priority to CN201710649506.9A priority Critical patent/CN107362450A/en
Publication of CN107362450A publication Critical patent/CN107362450A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/02Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/004Magnetotherapy specially adapted for a specific therapy
    • A61N2/006Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue

Abstract

A kind of transcranial magnetic stimulation circuit, stimulator and its magnetic field impulse generation method, the circuit include:At least two inductance coils, dc source, charging circuit, discharge circuit and the controller of inductance coil, controller control at least two inductance coil synchronously to produce magnetic field impulse by electronic switch.This method includes:Overlap the center line of the inductance coil;Controller output pulse sequence controls electronic switch, the inductance coil is synchronously produced magnetic field impulse, superposition, which forms transcranial magnetic stimulation device, stimulates the magnetic field impulse needed.The transcranial magnetic stimulation device includes pillow and above-mentioned transcranial magnetic stimulation circuit, and the pillow sets accommodating cavity, and the inductance coil of transcranial magnetic stimulation circuit is arranged at the center line coincidence of the accommodating cavity and all inductance coils of pillow.The present invention synchronously produces the magnetic field impulse that magnetic field impulse synthesizes stimulation by coupling using multiple coils, substantially reduces the pulse current of single coil needs, is easy to transcranial magnetic stimulation device to be miniaturized.

Description

Transcranial magnetic stimulation circuit, stimulator and its magnetic field impulse generation method
Technical field
The present invention relates to transcranial magnetic stimulation, more particularly to a kind of transcranial magnetic stimulation circuit, transcranial magnetic stimulation device and its magnetic Pulse generation method.
Background technology
The general principle of transcranial magnetic stimulation (Transcranial Magnetic Stimulation, TMS) is to use the power on Pulse current in inductance coil produces pulsed magnetic field.As shown in figure 1, traditional transcranial magnetic stimulation device typically uses rlc circuit Structure, R is resistance in Fig. 1, and L is inductance, and C is electric capacity, as follows with AC-powered, its operation principle:AC power is carried out Boosting and filtering;Controlling switch K1 is closed, and K2 disconnects, and quick charge is carried out to electric capacity C;Controlling switch K1 disconnects, K2 closures, electricity Hold C electric discharges, make the electric current in inductance coil L that quick change occur and produce pulsed magnetic field using LC oscillating circuits, individual pulse Width depend on lc circuit cycle of oscillation T
According to the inductance energy formula J of inductance coilL=0.5 × L × I2, to improve magnetic field impulse caused by inductance coil L Magnetic induction intensity (magnetic induction intensity for referring generally to certain point on inductance coil central shaft), it is necessary to improve electric capacity C charging electricity Pressure, inductance coil L can be just set to obtain big pulse current, but too high electric current can cause inductance coil easily to generate heat, coil insulation Intensity difficulty increase, the electric capacity C charging intervals extends, controlling switch it is pressure-resistant must increase, circuit-line loss increase etc. one Series of problems, so the design and fabrication scheme of product are often the result of multifactor balance, finally make device structure complexity, body The huge, production cost of product and use cost are all higher, and equipment miniaturization difficult to realize.
The content of the invention
It is an object of the invention to provide a kind of transcranial magnetic stimulation circuit, stimulator and its magnetic field impulse generation method, to solve At least one of drawbacks described above existing for prior art.
For the above-mentioned purpose, the technical solution adopted by the present invention is as follows:
A kind of transcranial magnetic stimulation circuit, the transcranial magnetic stimulation circuit include:
At least two inductance coils;
Dc source, at least two inductor wire is connected and composed by electronic switch and at least two inductance coil The charging circuit of circle;
The discharge circuit of at least two inductance coil;And
Controller, it is connected with the control terminal of the electronic switch, for controlling at least two inductance coil synchronously to produce Magnetisation pulse.
Preferably, first electricity of the transcranial magnetic stimulation circuit also including quantity identical with least two inductance coil Resistance, they connect correspondingly with least two inductance coil, for adjusting filling at least two inductance coil Discharge time constant, ensure that at least two inductance coil synchronously produces magnetic field impulse.
Preferably, the series arm that the discharge circuit includes second resistance and diode forms.
A kind of magnetic field impulse generation method of transcranial magnetic stimulation device, wherein, the transcranial magnetic stimulation circuit of the transcranial magnetic stimulation device Including:
At least two inductance coils;
Dc source, at least two inductor wire is connected and composed by electronic switch and at least two inductance coil The charging circuit of circle;
The discharge circuit of at least two inductance coil;And
Controller, it is connected with the control terminal of the electronic switch, for controlling at least two inductance coil synchronously to produce Magnetisation pulse;
The magnetic field impulse generation method of the transcranial magnetic stimulation device includes:
Overlap the center line of at least two inductance coil;And
The controller output pulse sequence controls the electronic switch, at least two inductance coil is synchronously produced Magnetic field impulse, magnetic field impulse superposition, which forms transcranial magnetic stimulation device, caused by synchronization stimulates the magnetic field impulse needed.
Preferably, the generation method also includes:The state modulator that the controller is inputted according to user its export pulse Frequency, and then control the generation frequency of magnetic field impulse.
Preferably, the generation method also includes:Its pulse for exporting of the state modulator that the controller is inputted according to user Width, and then control magnetic field impulse intensity.
Preferably, the generation method also includes:The state modulator that the controller is inputted according to user its export pulse Frequency, and then control the generation frequency of magnetic field impulse;And the state modulator that is inputted according to user of the controller its arteries and veins for exporting The width of punching, and then control the intensity of magnetic field impulse.
In the magnetic field impulse generation method of above-mentioned transcranial magnetic stimulation device, it is preferable that the transcranial magnetic stimulation device pierces through cranium magnetic Excitation circuit also includes the first resistor of quantity identical with least two inductance coil, and they are with least two inductor wire Circle is connected correspondingly, for adjusting the charge and discharge electrical time constant of at least two inductance coil, ensure described at least two Individual inductance coil synchronously produces magnetic field impulse.
A kind of transcranial magnetic stimulation device, the transcranial magnetic stimulation device includes transcranial magnetic stimulation circuit and pillow, described to be pierced through cranium magnetic Excitation circuit includes:
At least two inductance coils;
Dc source, at least two inductor wire is connected and composed by electronic switch and at least two inductance coil The charging circuit of circle;
The discharge circuit of at least two inductance coil;And
Controller, it is connected with the control terminal of the electronic switch, for controlling at least two inductance coil synchronously to produce Magnetisation pulse;
The pillow sets accommodating cavity, and the accommodating cavity is relative with the sleep inducing area of brain during use, transcranial magnetic stimulation At least two inductance coil of circuit is arranged at the accommodating cavity of pillow and the center line of all inductance coils overlaps, and holds The top for putting at least two inductance coils described in intracavitary sets cushion pad.
In some more preferably transcranial magnetic stimulation device, at least two inductance coil of transcranial magnetic stimulation circuit is concentric.
Compared with prior art, the present invention at least has the advantages that:Magnetic field impulse is synchronously produced using multiple coils The magnetic field impulse of stimulation is synthesized by coupling technique, the pulse current that so single inductance coil needs is greatly reduced, both avoided Coil existing for existing transcranial magnetic stimulation device easily generates heat, the increase of the difficulty of coil insulation intensity, capacitor charging time are long, control The problems such as system switch is pressure-resistant to be increased, line loss increase, while it is easy to transcranial magnetic stimulation device to realize miniaturization.
Brief description of the drawings
Fig. 1 is the circuit diagram of traditional transcranial magnetic stimulation device;
Fig. 2 is the schematic diagram of one embodiment transcranial magnetic stimulation circuit;
Fig. 3 is the structural representation of one embodiment transcranial magnetic stimulation device;
Fig. 4 is the explosive view of Fig. 3 transcranial magnetic stimulation devices.
Embodiment
The present invention will be further described with reference to the accompanying drawings and examples.
Reference picture 2, the transcranial magnetic stimulation circuit include:Three inductance coils L1, L2, L3, dc source VC, three inductance Coil L1, L2, L3 discharge circuit, controller.Dc source VC is connected by electronic switch K and three inductance coils L1, L2, L3 Connect the charging circuit for forming three inductance coils L1, L2, L3.Controller is connected with electronic switch K control terminal, with control three Inductance coil L1, L2, L3 synchronously produce magnetic field impulse.Discharge circuit includes the series connection branch that second resistance R and diode D are composed in series Road.
The magnetic field impulse generation method of above-mentioned transcranial magnetic stimulation circuit is as follows:Make three inductance coils L1, L2, L3 center line Overlap;The controller output pulse sequence controls the electronic switch K, three inductance coils L1, L2, L3 is synchronously produced magnetic Pulse, magnetic field impulse superposition, which forms transcranial magnetic stimulation device, caused by synchronization stimulates the magnetic field impulse needed.Further, the generation side Method can also include:It exports the frequency of pulse to the state modulator that the controller inputs according to user, and then controls magnetic field impulse Generation frequency.It can also include:The width of its pulse exported of the state modulator that the controller is inputted according to user, and then Control the intensity of magnetic field impulse.
Must have pulse high current to solve single inductance coil in traditional rlc circuit structure could produce high intensity The problem of magnetic field impulse, above-mentioned transcranial magnetic stimulation circuit employ two and opened one's minds:1) RL circuit structures are used, with small-pulse effect electricity Stream makes the magnetic field impulse of single inductance coil generation some strength.2) use synchronous coupling technique, it is multiple with one heart (or center line overlap ) inductance coil synchronization generation magnetic field impulse, according to magnetic flux density vector principle of stacking, make the magnetic field impulse after superposition in central shaft The intensity at upper any point reaches design load;Specifically in the embodiment depicted in figure 2, it is assumed that three inductance coils L1, L2, L3 are passed to Magnetic induction intensity caused by H points is respectively B on center shaft after same direction current1、B2、B3, then in H points position after synchronous coupling Magnetic induction density B=B1+B2+B3.After above-mentioned synchronous coupling technique, pulse current that single inductance coil needs can be with Substantially reduce, can both avoid coil from easily generating heat, the difficulty of coil insulation intensity increases, capacitor charging time extends, control Switch it is pressure-resistant increase, line loss increase a series of problems, such as, while be easy to transcranial magnetic stimulation device realize miniaturization.This area skill Art personnel should be appreciated that although three inductance coils are employed in embodiment illustrated in fig. 2 synchronously to be coupled, in practical application In, two inductance coils can be used as needed, coupling can also be synchronized using greater number of inductance coil.
In the above-described embodiments, magnetic field impulses, transcranial magnetic stimulation are produced in order to ensure that three inductance coils L1, L2, L3 are synchronous Circuit also includes three first resistors R1, R2, R3, and three first resistors R1, R2, R3 and three inductance coils L1, L2, L3 are one by one Accordingly connect.By the design of the resistance value to three first resistors R1, R2, R3, make three inductance coils L1, L2, L3 Charge and discharge electrical time constant approximately equal, so that it is guaranteed that magnetic field impulse can be produced synchronously.
Above-mentioned transcranial magnetic stimulation circuit and magnetic field impulse generation method efficiently solve traditional warp by direct current TMS coupling techniques A series of problems caused by the big pulse current of single inductance coil needs, can simplify device structure, drop in cranium magnetic stimulator Low equipment power dissipation, equipment production cost is reduced, can be widely used for manufacturing various miniature transcranial magnetic stimulation devices.
Fig. 3 and Fig. 4 shows a kind of structure of typical transcranial magnetic stimulation device, and as shown in Figure 3 and Figure 4, this is pierced through cranium magnetic Swashing device includes pillow 1 and transcranial magnetic stimulation circuit.Transcranial magnetic stimulation circuit can use any one above-mentioned transcranial magnetic stimulation Circuit.Pillow 1 sets accommodating cavity 11, and the accommodating cavity 11 is relative with the sleep inducing area of brain during use, and transcranial magnetic stimulation is electric All inductance coils on road are arranged at the accommodating cavity 11 of pillow 1, and all inductance coils are concentric, inductance coil in accommodating cavity 11 Top set cushion pad 2.The contact that cushion pad 2 is used between cushioned head and inductance coil, and ensure what is gone to bed Comfort level.The top of cushion pad 2 is also provided with a protection pad 4.
All inductance coils of transcranial magnetic stimulation circuit are arranged in a box body 3, and there is a through hole at the middle part of box body 3 31, the center line of all inductance coils of transcranial magnetic stimulation circuit overlaps with the center line of the through hole 31 of box body 3, the institute of pillow 1 The bottom of chamber for stating accommodating cavity 11 sets positioning convex portion 12, the through hole 31 of box body 3 and the phase of the positioning convex portion 12 of accommodating cavity 11 It is chimeric.Cushion pad 2 set bore 21.
For pillow 1 preferably using pillow made of memory sponge or latex material, cushion pad 2, which preferably uses, recalls cotton or latex material Manufactured cushion pad.Protection pad 4 can be made of gel.
The present invention is described in detail above by specific embodiment, these detailed description are only limited to help Skilled artisan understands that present disclosure, can not be interpreted as limiting the scope of the invention.Art technology Various retouchings that personnel are carried out under present inventive concept to such scheme, equivalent transformation etc. should be included in the protection model of the present invention In enclosing.

Claims (10)

1. a kind of transcranial magnetic stimulation circuit, it is characterised in that the transcranial magnetic stimulation circuit includes:
At least two inductance coils;
Dc source, at least two inductance coil is connected and composed by electronic switch and at least two inductance coil Charging circuit;
The discharge circuit of at least two inductance coil;And
Controller, it is connected with the control terminal of the electronic switch, for controlling at least two inductance coil synchronously to produce magnetic Pulse.
2. transcranial magnetic stimulation circuit according to claim 1, it is characterised in that:The transcranial magnetic stimulation circuit also include with The first resistor of the identical quantity of at least two inductance coil, they go here and there correspondingly with least two inductance coil Connection, for adjusting the charge and discharge electrical time constant of at least two inductance coil, ensure that at least two inductance coil is synchronous Produce magnetic field impulse.
3. transcranial magnetic stimulation circuit according to claim 1, it is characterised in that:The discharge circuit include second resistance and The series arm of diode composition.
A kind of 4. magnetic field impulse generation method of transcranial magnetic stimulation device, it is characterised in that the transcranial magnetic stimulation of the transcranial magnetic stimulation device Circuit includes:
At least two inductance coils;
Dc source, at least two inductance coil is connected and composed by electronic switch and at least two inductance coil Charging circuit;
The discharge circuit of at least two inductance coil;And
Controller, it is connected with the control terminal of the electronic switch, for controlling at least two inductance coil synchronously to produce magnetic Pulse;
The magnetic field impulse generation method of the transcranial magnetic stimulation device includes:
Overlap the center line of at least two inductance coil;And
The controller output pulse sequence controls the electronic switch, at least two inductance coil is synchronously produced magnetic arteries and veins Punching, magnetic field impulse superposition, which forms transcranial magnetic stimulation device, caused by synchronization stimulates the magnetic field impulse needed.
5. the magnetic field impulse generation method of transcranial magnetic stimulation device according to claim 4, it is characterised in that the generation method is also Including:It exports the frequency of pulse to the state modulator that the controller inputs according to user, and then controls the generation frequency of magnetic field impulse Rate.
6. the magnetic field impulse generation method of transcranial magnetic stimulation device according to claim 4, it is characterised in that the generation method is also Including:The width of its pulse exported of the state modulator that the controller is inputted according to user, and then control the intensity of magnetic field impulse.
7. the magnetic field impulse generation method of transcranial magnetic stimulation device according to claim 4, it is characterised in that the generation method is also Including:It exports the frequency of pulse to the state modulator that the controller inputs according to user, and then controls the generation frequency of magnetic field impulse Rate;And the width of state modulator its pulse exported that the controller is inputted according to user, and then control the strong of magnetic field impulse Degree.
8. the magnetic field impulse generation method of transcranial magnetic stimulation device according to claim 4, it is characterised in that:The transcranial magnetic stimulation The transcranial magnetic stimulation circuit of device also includes the first resistor of quantity identical with least two inductance coil, they with it is described extremely Few two inductance coils are connected correspondingly, for adjusting the charge and discharge electrical time constant of at least two inductance coil, are protected Demonstrate,prove at least two inductance coil and synchronously produce magnetic field impulse.
9. a kind of transcranial magnetic stimulation device, it is characterised in that the transcranial magnetic stimulation device includes:
Transcranial magnetic stimulation circuit, the transcranial magnetic stimulation circuit include:
At least two inductance coils;
Dc source, at least two inductance coil is connected and composed by electronic switch and at least two inductance coil Charging circuit;
The discharge circuit of at least two inductance coil;And
Controller, it is connected with the control terminal of the electronic switch, for controlling at least two inductance coil synchronously to produce magnetic Pulse;
Pillow, the pillow set accommodating cavity, and the accommodating cavity is relative with the sleep inducing area of brain during use, transcranial magnetic stimulation At least two inductance coil of circuit is arranged at the accommodating cavity of pillow and the center line of all inductance coils overlaps, and holds The top for putting at least two inductance coils described in intracavitary sets cushion pad.
10. transcranial magnetic stimulation device according to claim 9, it is characterised in that:Described at least the two of transcranial magnetic stimulation circuit Individual inductance coil is concentric.
CN201710649506.9A 2017-07-31 2017-07-31 Transcranial magnetic stimulation circuit, stimulator and its magnetic field impulse generation method Pending CN107362450A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710649506.9A CN107362450A (en) 2017-07-31 2017-07-31 Transcranial magnetic stimulation circuit, stimulator and its magnetic field impulse generation method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710649506.9A CN107362450A (en) 2017-07-31 2017-07-31 Transcranial magnetic stimulation circuit, stimulator and its magnetic field impulse generation method

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CN107362450A true CN107362450A (en) 2017-11-21

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040122281A1 (en) * 2002-12-21 2004-06-24 Neuralieve, Inc. Means and methods for treating headaches
US8376925B1 (en) * 2009-12-01 2013-02-19 Robert Glenn Dennis Magnetic system for treatment of a tissue
CN203556061U (en) * 2013-10-10 2014-04-23 深圳英智科技有限公司 Transcranial stimulation apparatus
WO2016094390A1 (en) * 2014-12-08 2016-06-16 Coats Andrew Justin Stewarts Magnetic induction anti-snoring device
CN208003266U (en) * 2017-07-31 2018-10-26 深圳生理科技有限公司 Transcranial magnetic stimulation sleeping aid pillow and its circuit

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040122281A1 (en) * 2002-12-21 2004-06-24 Neuralieve, Inc. Means and methods for treating headaches
US8376925B1 (en) * 2009-12-01 2013-02-19 Robert Glenn Dennis Magnetic system for treatment of a tissue
CN203556061U (en) * 2013-10-10 2014-04-23 深圳英智科技有限公司 Transcranial stimulation apparatus
WO2016094390A1 (en) * 2014-12-08 2016-06-16 Coats Andrew Justin Stewarts Magnetic induction anti-snoring device
CN208003266U (en) * 2017-07-31 2018-10-26 深圳生理科技有限公司 Transcranial magnetic stimulation sleeping aid pillow and its circuit

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