CN107308015A - A kind of preparation method of effervesce toothpaste - Google Patents
A kind of preparation method of effervesce toothpaste Download PDFInfo
- Publication number
- CN107308015A CN107308015A CN201710371033.0A CN201710371033A CN107308015A CN 107308015 A CN107308015 A CN 107308015A CN 201710371033 A CN201710371033 A CN 201710371033A CN 107308015 A CN107308015 A CN 107308015A
- Authority
- CN
- China
- Prior art keywords
- parts
- weight
- xylitol
- mixed
- toothpaste
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/22—Gas releasing
- A61K2800/222—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Abstract
The invention belongs to daily use chemicals technical field, and in particular to a kind of preparation method of effervesce toothpaste, and raw material of the invention includes following components：50~75 parts of NMFs, 8~15 parts of rubbing agents, 10~15 parts of diluents, 2~3 parts of sodium lauryl sulfonates, 8~15 parts of titanium dioxides, 3~5 parts of tea oil, 1~1.5 portion of peppermint oil, 0.2~0.5 part of essence, 3~6 parts of enzyme detergent, 0.1~0.2 part of sodium benzoate, 1~2 part of sodium carboxymethylcellulose and 0.1~0.3 part of B B-complex, the present invention has been specifically added enzyme detergent and effervescent agent, for improving the efficiency that cleans one's teeth, so as to reduce the brushing abrasion of tooth, the invention also discloses the preparation method of effervescent agent, the toothpaste of the present invention, which has, to clean one's teeth comprehensively, tartar can effectively be removed, the advantages of few to tooth wear, by good promotion prospect.
Description
【Technical field】
The present invention relates to daily use chemicals technical field, and in particular to a kind of preparation method of effervesce toothpaste.
【Background technology】
Toothpaste is the cleaning supplies commonly used in daily life, and major part toothpaste relies primarily on mechanical friction mode and removed at present
Spot on tooth, traditional mechanical friction cleaning mode, it is difficult to accomplish cleaning comprehensively, often in teeth space, at all, tooth deformity etc.
The position that toothbrush is difficult to rub has swill residual, and swill produces acidic materials by fermenting and corrodes tooth, together
When make implication carry unpleasant putrefactive odor, have a strong impact on communication, with the continuation heap fermentation of swill can also produce it is hard
Calculus dentalis, carious tooth, gingival atrophy bleeding, loss of tooth even carcinoma of mouth, had a strong impact on the quality of life of people；Secondly,
If simply relying on friction removes the stain of tooth, it is necessary to repeatedly rub back and forth, and the tooth of dental surface can excessively be destroyed by rubbing
Enamel, makes dental surface become coarse, and tooth stain is easier to be deposited on dental surface.It would therefore be highly desirable to which inventing one kind itself has clearly
Clean global function is, it is necessary to the toothpaste of mechanical friction number of times less with regard to that can clean one's teeth.
【The content of the invention】
The goal of the invention of the present invention is to provide a kind of preparation method of effervesce toothpaste, the present invention by introduce enzyme detergent and
Effervescent agent solves above-mentioned problem, of the invention to be aided in by the enzymolysis of enzyme detergent and the effervescent effect of effervescent agent
Clean one's teeth, can accomplish to clean one's teeth comprehensively, clean one's teeth efficiency high, can reduce the brushing abrasion of tooth.
To achieve these goals, the technical solution adopted by the present invention is as follows：A kind of preparation method of effervesce toothpaste, including
Following steps：(1) count by weight, by 0.2~0.5 part of essence, 0.1~0.2 part of sodium benzoate, 0.1~0.3 part of compound dimension
Raw element and 10~15 parts of diluents are put into reactor, 5~10min are stirred under 1000~1800r/min mixing speed, so
Primary diluent is obtained to 6.0~6.5 with lemon acid for adjusting pH value afterwards, it is last clean toward 1~3 part of enzyme of addition in primary diluent
Agent and 5~9 parts of effervescent agents, are stirred 15 minutes under 300~350r/min mixing speed, obtain diluting suspension；
(2) count by weight, by 8~15 parts of rubbing agents, 2~3 parts of sodium lauryl sulfonates, 8~15 parts of titanium dioxides, 3~5
After part tea oil, 1~1.5 portion of peppermint oil and 1~2 part of sodium carboxymethylcellulose and 50~75 parts of NMFs mixing, with 0.01~
0.15m3It is the helical static mixing tube that 20mm, length are 250~300mm that/min flow velocity, which is passed through internal diameter, mixed through helical static
Bed material glue is obtained after closing pipe extrusion；
(3) count by weight, cold type is added to after 60~90 parts of bed material glues and 10~15 parts of dilution suspensions are mixed
In single screw extrusion machine, screw slenderness ratio be 10~15, screw speed be 80~100r/min and extrusion hasten as 0.25~
0.5m3After being extruded under conditions of/min, into vacuum degassing machine, 5~10min is kept under conditions of -120~-80kPa,
Obtain a kind of effervesce toothpaste.
In the present invention, as further illustrating, the effervescent agent described in step (1) can be prepared by following methods：By weight
Number meter, after 15~25 parts of xylitols and 3~5 parts of water are mixed, is positioned over pressure-resistant seal tank, is heated to 93~95 DEG C, stirring
Mix under the stirring that speed is 300~350r/min, stir 5~10min, obtain xylitol oil, stop heating, by 1~3 part of micro mist
Silica gel and 5~8 portions of mannitol add xylitol oil, and 1~2min is stirred with 1000~1500r/min mixing speed, then will
Pressure increases to 5.5~6.0MPa in hermetically sealed can, under 1000~1500r/min mixing speed, compressed air is passed through many
Hole aeration spray head is with 0.3m3/ min speed is filled with xylitol oil, and the consumption of compressed air uses for every cube of xylitol oil
0.5m3, inflate and finish and obtained after cooling down many inflation xylitols, finally inflation xylitol is chilled to after -15~-5 DEG C, ball is used
Grinding machine is ground, and crosses 40~80 mesh sieves, obtains effervescent agent.
In the present invention, as further illustrating, the diluent described in step (1) is saturation xylose alcohol solution.
In the present invention, as further illustrating, the B B-complex described in step (1) is by being 5~15 by weight：5
~15 vitamin C and vitamin E is mixed.
In the present invention, as further illustrating, the enzyme detergent described in step (1) is by being 5~9 by weight：8~11：2
~4：3~7 lysozyme, amylase, cellulase and protease is mixed.
In the present invention, as further illustrating, the NMF described in step (2) by be by weight 50~60：15
~18：10~15 glycerine, propane diols and polyethylene glycol 400 is mixed.
In the present invention, as further illustrating, the rubbing agent described in step (2) is by being 16~23 by weight：3~7
Silicon dioxide powder and pounce mix.
The function introduction of part material is as follows：
Thickener, the in the present invention effect of thickener is that the viscosity for increasing toothpaste is allowed to form lotion.
Effervescent agent, the in the present invention effect of effervescent agent is used as adjunct detergent, and the gas discharged by effervesce is helped
Clean tooth.
Enzyme detergent, in the present invention enzyme detergent function as a kind of cleaning agent, by enzymatic reaction be on tooth
Swill is decomposed, and is easy to remove totally.
NMF, the in the present invention effect of NMF is the stabilization for maintaining toothpaste, prevents toothpaste from solidifying change in flexible pipe
Firmly, and make lotion that there is gloss.
B B-complex, the in the present invention effect of B B-complex is used as the nutritional agents of gum, and gum is repaired in help
Damage.
Sodium carboxymethylcellulose, in the present invention sodium carboxymethylcellulose function as adhesive, make in toothpaste
Each composition is uniformly dispersed.
Sodium lauryl sulfonate, the effect of sodium lauryl sulfonate in the present invention is foaming agent, for rinsing the mouth in dirt
Dirt.
Rubbing agent, the in the present invention effect of rubbing agent is to remove tartar, bacterial plaque etc. by mechanical friction.
In summary, by adopting the above-described technical solution, the beneficial effects of the invention are as follows：
1. the method that the present invention is inflated using sealing pressing prepares effervescent agent.Effervescent agent prepared by this method, it is relatively conventional
Effervescent agent chemical reaction deflate effervescent principle, effervescent agent of the invention have the advantages that it is corrosion-free, non-stimulated, it is safer
It is stable.First, effervescent agent of the invention is made of to wrap up compressed gas, effervescent agent anacidity in disintegrating procedue using xylitol alcohol
Property material participate in, no acidic material produce, therefore, it is possible to be prevented effectively from acidic materials corrosion tooth；Secondly, effervesce of the invention
Agent is used in the fabrication process with the effervescent agent that traditional chemical reacts the present invention compared with class has strong oxidizing property, acid effervescent agent
Be that property is stable, gentle raw material, and disintegrating procedue is physical process, therefore oral mucosa non-oxidation, acid etching etc. are pierced
Swash；Finally, effervescent agent of the invention is not allowed to be also easy to produce flatulence problem during production and raw storage, with good stable
Property because the present invention effervescent agent be using after fusing xylitol inflation be made, the fusing point that xylitol has in itself be 92~
96 DEG C, the temperature during the production and storage of toothpaste, it is impossible to reach xylitol fusing point, so effervescent agent will not production and
Thermally decomposed during storage, therefore the effervescent agent of the present invention is not allowed to be also easy to produce flatulence problem, with good stability.
2. introducing enzyme detergent and effervescent agent in a kind of effervesce toothpaste of the invention, make cleaning of teeth more thorough, clean one's teeth
Efficiency high, effectively reduces tooth brushing abrasion.Enzyme detergent in the present invention is made up of a variety of efficient organized enzymes, these
Organized enzyme is added according to the soft dirty composition specific aim of the residual on tooth, and organized enzyme can be on tooth during brushing teeth
The soft dirt of bonding decomposed by enzymatic reaction, form the small molecule easily cleared up, disintegration of these small molecules in effervescent agent
The gas bleed discharged in journey by effervescent agent is fallen and is distributed in foam, so only needs less Rubbing number just can be tooth
Tooth cleaning is clean, therefore, and a kind of effervesce toothpaste of the invention, which has, reduces tooth brushing abrasion, and clean one's teeth efficient advantage；This
Outside, a kind of calving disaggregation of effervesce toothpaste of the invention effervescent agent in use can also be flushed to organized enzyme the seam of tooth
Place that the toothbrushes such as gap, root of the tooth can't reach simultaneously carries out enzymatic decomposition cleaning action, thus the present invention the cleaning of effervesce toothpaste more
Thoroughly.
3. in the production process in a kind of effervesce toothpaste of the invention, helical static is used after foamer ingredient is added
Mixing tube is mixed and cold type Single screw extrusion hybrid technology technique carries out material mixing, and the technique has efficiency high, can be continuous
Bubbled in operation, mixed process the advantages of disperseing evenly less.
【Embodiment】
Embodiment 1：
1. prepare：
The preparation of effervescent agent：Count by weight, after 15 parts of xylitols and 3 parts of water are mixed, be positioned over pressure-resistant seal tank,
93 DEG C are heated to, low whipping speed obtains xylitol oil, stop heating, by 1 part under 300r/min stirring, to stir 5min
Superfine silica gel powder and 5 portions of mannitol add xylitol oil, 1min are stirred with 1000r/min mixing speed, then by hermetically sealed can
Pressure increases to 5.5MPa, so that under 1000r/min mixing speed stirring, compressed air is filled with wood by porous aeration spray head
In sugar alcohol oil, many inflation xylitols are obtained after cooling, finally inflation xylitol is chilled to after -15 DEG C, ball mill grinding powder is used
It is broken, and 40 mesh sieves are crossed, obtain effervescent agent.
The preparation of saturation xylose alcohol solution：Excessive xylitol is dissolved in water, upper solution is taken, saturation xylitol water is obtained
Solution.
The preparation of B B-complex：Count by weight, 5 parts of vitamin Cs and 5 parts of vitamin Es are mixed.
The preparation of NMF：Count by weight, 50 parts of glycerine, 15 parts of propane diols and 10 parts of polyethylene glycol 400s mixed,
Obtain NMF.
The preparation of rubbing agent：Count by weight, 16 parts of silica and 3 parts of pounces are mixed, rubbing agent is obtained.
The preparation of enzyme detergent：Agent by weight, by 5 parts of lysozymes, 8 parts of amylase, 2 parts of cellulases and 3 portions of eggs
White enzyme mixing, obtains enzyme detergent.
The material that above-mentioned early stage is prepared is used for following preparation methods.
2. a kind of preparation of effervesce toothpaste：Comprise the following steps：
(1) count by weight, by 0.2 part of essence, 0.1 part of sodium benzoate, 0.1 part of B B-complex and 10 parts of diluents
It is put into reactor, 5min is stirred under 1000r/min mixing speed, then obtains one to 6.0 with lemon acid for adjusting pH value
Level dilution, it is last toward 1 part of enzyme detergent of addition and 5 parts of effervescent agents in primary diluent, stirred under 300r/min mixing speed
Mix 15 minutes, obtain diluting suspension；
(2) count by weight, by 8 parts of rubbing agents, 2 portions of sodium lauryl sulfonates, 8 portions of titanium dioxides, 3 portions of tea oil, 1 portion of peppermint
After oil and 1 part of sodium carboxymethylcellulose and 50 parts of NMF mixing, with 0.01m3/ min flow velocity is passed through internal diameter for 20mm, length
For 250mm helical static mixing tube, bed material glue is obtained after being extruded through helical static mixing tube；
(3) count by weight, being added to cold type single screw rod after 60 parts of bed material glues and 10 parts of dilution suspensions are mixed squeezes
Go out in machine, be that 10, screw speed is 80r/min and extrusion hastens as 0.25m in screw slenderness ratio3Extruded under conditions of/min
Afterwards, into vacuum degassing machine, 5min is kept under conditions of -120kPa, a kind of effervesce toothpaste is obtained.
Embodiment 2：
1. prepare：
The preparation of effervescent agent：Count by weight, after 25 parts of xylitols and 5 parts of water are mixed, be positioned over pressure-resistant seal tank,
95 DEG C are heated to, low whipping speed obtains xylitol oil, stop heating, by 3 parts under 350r/min stirring, to stir 10min
Superfine silica gel powder and 8 portions of mannitol add xylitol oil, 2min are stirred with 1500r/min mixing speed, then by hermetically sealed can
Pressure increases to 6.0MPa, so that under 1500r/min mixing speed stirring, compressed air is filled with wood by porous aeration spray head
In sugar alcohol oil, many inflation xylitols are obtained after cooling, finally inflation xylitol is chilled to after -5 DEG C, ball mill grinding powder is used
It is broken, and 80 mesh sieves are crossed, obtain effervescent agent.
The preparation of saturation xylose alcohol solution：Excessive xylitol is dissolved in water, upper solution is taken, saturation xylitol water is obtained
Solution.
The preparation of B B-complex：Count by weight, 15 parts of vitamin Cs and 15 parts of vitamin Es are mixed.
The preparation of NMF：Count by weight, 60 parts of glycerine, 18 parts of propane diols and 15 parts of polyethylene glycol 400s mixed,
Obtain NMF.
The preparation of rubbing agent：Count by weight, 23 parts of silica and 7 parts of pounces are mixed, rubbing agent is obtained.
The preparation of enzyme detergent：Agent by weight, by 9 parts of lysozymes, 11 parts of amylase, 4 parts of cellulases and 7 portions of eggs
White enzyme mixing, obtains enzyme detergent.
The material that above-mentioned early stage is prepared is used for following preparation methods.
2. a kind of preparation of effervesce toothpaste：Comprise the following steps：
(1) count by weight, by 0.5 part of essence, 0.2 part of sodium benzoate, 0.3 part of B B-complex and 15 parts of diluents
It is put into reactor, 10min is stirred under 1800r/min mixing speed, is then obtained with lemon acid for adjusting pH value to 6.5
Primary diluent, it is last toward 3 parts of enzyme detergent of addition and 9 parts of effervescent agents in primary diluent, under 350r/min mixing speed
Stirring 15 minutes, obtains diluting suspension；
(2) count by weight, by 15 parts of rubbing agents, 3 parts of sodium lauryl sulfonates, 15 parts of titanium dioxides, 5 parts of tea oil, 1.5 parts
After peppermint oil and 2 parts of sodium carboxymethylcelluloses and 75 parts of NMF mixing, with 0.15m3/ min flow velocity be passed through internal diameter for 20mm,
Length is 250~300mm helical static mixing tube, and bed material glue is obtained after being extruded through helical static mixing tube；
(3) count by weight, being added to cold type single screw rod after 90 parts of bed material glues and 15 parts of dilution suspensions are mixed squeezes
Go out in machine, be that 15, screw speed is 100r/min and extrusion hastens as 0.5m in screw slenderness ratio3Extruded under conditions of/min
Afterwards, into vacuum degassing machine, 10min is kept under conditions of -80kPa, a kind of effervesce toothpaste is obtained.
Embodiment 3：
1. prepare：
The preparation of effervescent agent：Count by weight, after 20 parts of xylitols and 4 parts of water are mixed, be positioned over pressure-resistant seal tank,
94 DEG C are heated to, low whipping speed obtains xylitol oil, stop heating, by 2 under 325r/min stirring, to stir 7.5min
Part superfine silica gel powder and 6.5 portions of mannitol add xylitols oil, and 1.5min is stirred with 1250r/min mixing speed, then will be close
Pressure increases to 5.75MPa in sealed cans, so that under 1250r/min mixing speed stirring, compressed air is sprayed by porous aeration
Head is filled with xylitol oil, and many inflation xylitols are obtained after cooling, finally inflation xylitol is chilled to after -10 DEG C, ball milling is used
Machine is ground, and crosses 60 mesh sieves, obtains effervescent agent.
The preparation of saturation xylose alcohol solution：Excessive xylitol is dissolved in water, upper solution is taken, saturation xylitol water is obtained
Solution.
The preparation of B B-complex：Count by weight, 10 parts of vitamin Cs and 10 parts of vitamin Es are mixed.
The preparation of NMF：Count by weight, by 55 parts of glycerine, 16.5 parts of propane diols and 12.5 parts of polyethylene glycol 400s
Mixing, obtains NMF.
The preparation of rubbing agent：Count by weight, 19.5 parts of silica and 5 parts of pounces are mixed, rubbed
Agent.
The preparation of enzyme detergent：Agent by weight, by 7 parts of lysozymes, 9.5 parts of amylase, 3 parts of cellulases and 5 parts
Protease is mixed, and obtains enzyme detergent.
The material that above-mentioned early stage is prepared is used for following preparation methods.
2. a kind of preparation of effervesce toothpaste：Comprise the following steps：
(1) count by weight, 0.35 part of essence, 0.15 part of sodium benzoate, 0.2 part of B B-complex and 12.5 parts are dilute
Release agent to be put into reactor, 7.5min is stirred under 1400r/min mixing speed, then with lemon acid for adjusting pH value extremely
6.25, primary diluent is obtained, it is last toward 2 parts of enzyme detergent of addition and 7 parts of effervescent agents in primary diluent, in stirring for 325r/min
Mix and stirred 15 minutes under speed, obtain diluting suspension；
(2) count by weight, by 11.5 parts of rubbing agents, 2.5 parts of sodium lauryl sulfonates, 11.5 parts of titanium dioxides, 4 parts of tea
After oil, 1.25 portions of peppermint oils and 1.5 parts of sodium carboxymethylcelluloses and 62.5 parts of NMF mixing, with 0.08m3/ min flow velocity leads to
It is the helical static mixing tube that 20mm, length are 275mm to enter internal diameter, and bed material glue is obtained after being extruded through helical static mixing tube；
(3) count by weight, cold type single screw rod is added to after 75 parts of bed material glues and 12.5 parts of dilution suspensions are mixed
It is that 12.5, screw speed is 90r/min and extrusion hastens as 0.375m in screw slenderness ratio in extruder3Under conditions of/min
After extrusion, into vacuum degassing machine, 7.5min is kept under conditions of -100kPa, a kind of effervesce toothpaste is obtained.
Embodiment 4：
1. prepare：
The preparation of effervescent agent：Count by weight, after 17.5 parts of xylitols and 3.5 parts of water are mixed, be positioned over resistance to densification
Sealed cans, are heated to 93.5 DEG C, low whipping speed obtains xylitol oil under 313r/min stirring, to stir 6min, stops adding
2 parts of superfine silica gel powders and 6 portions of mannitol are added xylitol oil, 1min are stirred with 1125r/min mixing speed, then will by heat
Pressure increases to 5.8MPa in hermetically sealed can, so that under 1125r/min mixing speed stirring, compressed air is sprayed by porous aeration
Head is filled with xylitol oil, and many inflation xylitols are obtained after cooling, finally inflation xylitol is chilled to after -11 DEG C, ball milling is used
Machine is ground, and crosses 50 mesh sieves, obtains effervescent agent.
The preparation of saturation xylose alcohol solution：Excessive xylitol is dissolved in water, upper solution is taken, saturation xylitol water is obtained
Solution.
The preparation of B B-complex：Count by weight, 8 parts of vitamin Cs and 8 parts of vitamin Es are mixed.
The preparation of NMF：Count by weight, 55 parts of glycerine, 16 parts of propane diols and 12 parts of polyethylene glycol 400s mixed,
Obtain NMF.
The preparation of rubbing agent：Count by weight, 17 parts of silica and 4 parts of pounces are mixed, rubbing agent is obtained.
The preparation of enzyme detergent：Agent by weight, by 8 parts of lysozymes, 9 parts of amylase, 3 parts of cellulases and 5 portions of eggs
White enzyme mixing, obtains enzyme detergent.
The material that above-mentioned early stage is prepared is used for following preparation methods.
2. a kind of preparation of effervesce toothpaste：Comprise the following steps：
(1) count by weight, by 0.3 part of essence, 0.1 part of sodium benzoate, 0.1 part of B B-complex and 12 parts of diluents
It is put into reactor, 8min is stirred under 1300r/min mixing speed, then obtains one to 6.2 with lemon acid for adjusting pH value
Level dilution, it is last toward 1.6 parts of enzyme detergent of addition and 8 parts of effervescent agents in primary diluent, under 320r/min mixing speed
Stirring 15 minutes, obtains diluting suspension；
(2) count by weight, by 13 parts of rubbing agents, 3 parts of sodium lauryl sulfonates, 13 parts of titanium dioxides, 5 parts of tea oil, 1 part thin
After lotus oil and 1 part of sodium carboxymethylcellulose and 60 parts of NMF mixing, with 0.12m3/ min flow velocity is passed through internal diameter for 20mm, length
The helical static mixing tube for 260mm is spent, bed material glue is obtained after being extruded through helical static mixing tube；
(3) count by weight, being added to cold type single screw rod after 80 parts of bed material glues and 12 parts of dilution suspensions are mixed squeezes
Go out in machine, be that 13, screw speed is 85r/min and extrusion hastens as 0.3m in screw slenderness ratio3After being extruded under conditions of/min,
Into in vacuum degassing machine, 7min is kept under conditions of -90kPa, a kind of effervesce toothpaste is obtained.
Embodiment 5：
1. prepare：
The preparation of effervescent agent：Count by weight, after 24 parts of xylitols and 4 parts of water are mixed, be positioned over pressure-resistant seal tank,
94 DEG C are heated to, low whipping speed obtains xylitol oil, stop heating, by 1.5 under 338r/min stirring, to stir 6min
Part superfine silica gel powder and 7 portions of mannitol add xylitols oil, 2min are stirred with 1375r/min mixing speed, then by hermetically sealed can
Interior pressure increases to 6.0MPa, so that under 1375r/min mixing speed stirring, compressed air is filled with by porous aeration spray head
In xylitol oil, many inflation xylitols are obtained after cooling, finally inflation xylitol is chilled to after -8 DEG C, ball mill grinding powder is used
It is broken, and 75 mesh sieves are crossed, obtain effervescent agent.
The preparation of saturation xylose alcohol solution：Excessive xylitol is dissolved in water, upper solution is taken, saturation xylitol water is obtained
Solution.
The preparation of B B-complex：Count by weight, 13 parts of vitamin Cs and 13 parts of vitamin Es are mixed.
The preparation of NMF：Count by weight, 58 parts of glycerine, 16 parts of propane diols and 14 parts of polyethylene glycol 400s mixed,
Obtain NMF.
The preparation of rubbing agent：Count by weight, 22 parts of silica and 6 parts of pounces are mixed, rubbing agent is obtained.
The preparation of enzyme detergent：Agent by weight, by 8 parts of lysozymes, 10 parts of amylase, 3 parts of cellulases and 6 portions of eggs
White enzyme mixing, obtains enzyme detergent.
The material that above-mentioned early stage is prepared is used for following preparation methods.
2. a kind of preparation of effervesce toothpaste：Comprise the following steps：
(1) count by weight, by 0.4 part of essence, 0.2 part of sodium benzoate, 0.3 part of B B-complex and 14 parts of diluents
It is put into reactor, 9min is stirred under 1700r/min mixing speed, then obtains one to 6.4 with lemon acid for adjusting pH value
Level dilution, it is last toward 3 parts of enzyme detergent of addition and 8 parts of effervescent agents in primary diluent, stirred under 340r/min mixing speed
Mix 15 minutes, obtain diluting suspension；
(2) count by weight, by 14 parts of rubbing agents, 3 parts of sodium lauryl sulfonates, 14 parts of titanium dioxides, 7 parts of tea oil, 1.4 parts
After peppermint oil and 2 parts of sodium carboxymethylcelluloses and 70 parts of NMF mixing, with 0.14m3/ min flow velocity be passed through internal diameter for 20mm,
Length is 290mm helical static mixing tube, and bed material glue is obtained after being extruded through helical static mixing tube；
(3) count by weight, being added to cold type single screw rod after 88 parts of bed material glues and 14 parts of dilution suspensions are mixed squeezes
Go out in machine, be that 14, screw speed is 90r/min and extrusion hastens as 0.45m in screw slenderness ratio3Extruded under conditions of/min
Afterwards, into vacuum degassing machine, 9min is kept under conditions of -90kPa, a kind of effervesce toothpaste is obtained.
Comparative example 1：A kind of specific steps of the preparation method of toothpaste, raw material are substantially the same manner as Example 1, and difference exists
In：Step does not use enzyme detergent in (2).
Comparative example 2：A kind of specific steps of the preparation method of toothpaste, raw material are substantially the same manner as Example 1, and difference exists
In：Step does not use effervescent agent in (2).
Contrast experiment 1：
The time-consuming test of decontamination：7 pieces of close eggs of surface smooth degree are selected, with the paste of dyeing respectively in 7 pieces of eggs
The wide 0.5cm of 1cm one long vestige is scribbled on surface, and electricity consumption blowing drying allows it to cement the soft dirt for simulating adhesion tooth, so
Duck in drink the oral environment gargled of simulation afterwards, finally with the toothbrush difference dipping equivalent of 7 unified specifications by by comparative example
Toothpaste prepared by 1-2 and embodiment 1-5 method, the paste of the dyeing of egg surface is scrubbed with identical dynamics, and statistics is complete
Time when removing the paste of dyeing needed for each sample is time-consuming for decontamination, and testing result is shown in Table 1.
Contrast experiment 2：
Crevice cleaning rate is tested：Take 7 block length 4cm, wide 2cm surface to be evenly distributed with 100 a diameter of 1mm, depth to be
The test ceramic wafer of 1mm little groove, says that 10g dyeing pastes are uniformly smeared into the little groove of 7 pieces of test boards, electricity consumption is blown respectively
Wind is done, the soft dirt in simulation teeth space etc., the oral environment that simulation of then ducking in drink is gargled, finally with 7 unified specifications
The toothpaste by the method preparation by comparative example 1-2 and embodiment 1-5 of toothbrush difference dipping equivalent, with identical dynamics come backwash
Wash after 5min, the test ceramic wafer of statistics little groove has removed clean little groove number, calculates crevice cleaning rate.
Contrast experiment 1-2 experimental result is subjected to calculating detection, 1 is all the results are shown in Table.
Table 1：
| Group | Decontamination takes | Crevice cleaning rate |
| Comparative example 1 | 56s | 65% |
| Comparative example 2 | 45s | 55% |
| Embodiment 1 | 32s | 86% |
| Embodiment 2 | 31s | 86% |
| Embodiment 3 | 32s | 87% |
| Embodiment 4 | 30s | 88% |
| Embodiment 5 | 32s | 86% |
The result of table 1 shows：Decontamination takes, and shows the cleaning ability of a kind of toothpaste dirt soft to tooth, swill etc., clean
Ability is stronger, and decontamination is time-consuming shorter, and required mechanical friction is fewer, and brushing abrasion is also fewer, and above-mentioned experiment shows comparative example 1
It is time-consuming most long, the time-consuming most short explanation of embodiment 4 by add enzyme detergent can reach raising clean one's teeth efficiency, reduce brushing abrasion
Purpose；
Crevice cleaning rate, shows that toothpaste is difficult to the local cleaning capacity that mechanical friction is arrived to teeth space etc., embodies toothpaste
The thorough degree cleaned one's teeth, the thorough degree that cleans one's teeth of the higher explanation toothpaste of crevice cleaning rate is higher, and above-mentioned experiment shows that comparative example 2 is stitched
Gap clean rate is minimum, the crevice cleaning rate highest of embodiment 4, illustrate by add effervescent agent can reach improvement toothpaste clean one's teeth it is thorough
The purpose of bottom degree.
Described above is the detailed description for the present invention preferably possible embodiments, but embodiment is not limited to this hair
The equal change or modification change completed under bright patent claim, the technical spirit suggested by all present invention, all should belong to
Cover the scope of the claims in the present invention.
Claims (7)
1. a kind of preparation method of effervesce toothpaste, it is characterised in that：Comprise the following steps：
(1) count by weight, by 0.2~0.5 part of essence, 0.1~0.2 part of sodium benzoate, 0.1~0.3 part of B B-complex
It is put into 10~15 parts of diluents in reactor, 5~10min, Ran Houyong is stirred under 1000~1800r/min mixing speed
Lemon acid for adjusting pH value obtains primary diluent to 6.0~6.5, last toward addition 1~3 part of enzyme detergent and 5 in primary diluent
~9 parts of effervescent agents, are stirred 15 minutes under 300~350r/min mixing speed, obtain diluting suspension；
(2) count by weight, by 8~15 parts of rubbing agents, 2~3 parts of sodium lauryl sulfonates, 8~15 parts of titanium dioxides, 3~5 parts of tea
After oil, 1~1.5 portion of peppermint oil and 1~2 part of sodium carboxymethylcellulose and 50~75 parts of NMF mixing, with 0.01~0.15m3/
It is the helical static mixing tube that 20mm, length are 250~300mm that min flow velocity, which is passed through internal diameter, is extruded through helical static mixing tube
After obtain bed material glue；
(3) count by weight, cold type list spiral shell is added to after 60~90 parts of bed material glues and 10~15 parts of dilution suspensions are mixed
In bar extruder, screw slenderness ratio be 10~15, screw speed be 80~100r/min and extrusion hasten as 0.25~
0.5m3After being extruded under conditions of/min, into vacuum degassing machine, 5~10min is kept under conditions of -120~-80kPa,
Obtain a kind of effervesce toothpaste.
2. according to the method described in claim 1, it is characterised in that：Effervescent agent described in step (1) can be prepared by following methods：
Count by weight, after 15~25 parts of xylitols and 3~5 parts of water are mixed, be positioned over pressure-resistant seal tank, be heated to 93~95
DEG C, low whipping speed obtains xylitol oil, stops heating under 300~350r/min stirring, to stir 5~10min, by 1~
3 parts of superfine silica gel powders and 5~8 portions of mannitol add xylitol oil, and 1~2min is stirred with 1000~1500r/min mixing speed,
Then pressure in hermetically sealed can is increased into 5.5~6.0MPa, with 1000~1500r/min mixing speed, compressed air
By porous aeration spray head with 0.3m3/ min speed is filled with xylitol oil, and the consumption of compressed air is every cube of xylitol
Oil uses 0.5m3, inflate and finish and obtained after cooling down many inflation xylitols, inflation xylitol is finally chilled to -15~-5 DEG C
Afterwards, crushed with ball mill grinding, and cross 40~80 mesh sieves, obtain effervescent agent.
3. according to the method described in claim 1, it is characterised in that：Diluent described in step (1) is water-soluble for saturation xylitol
Liquid.
4. according to the method described in claim 1, it is characterised in that：B B-complex described in step (1) is by being 5 by weight
~15：5~15 vitamin C and vitamin E is mixed.
5. according to the method described in claim 1, it is characterised in that：Enzyme detergent described in step (1) is by being 5~9 by weight：
8~11：2~4：3~7 lysozyme, amylase, cellulase and protease is mixed.
6. according to the method described in claim 1, it is characterised in that：NMF described in step (2) by be by weight 50
~60：15~18：10~15 glycerine, propane diols and polyethylene glycol 400 is mixed.
7. according to the method described in claim 1, it is characterised in that：Rubbing agent described in step (2) by by weight for 16~
23：3~7 silicon dioxide powder and pounce is mixed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710371033.0A CN107308015A (en) | 2017-05-24 | 2017-05-24 | A kind of preparation method of effervesce toothpaste |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710371033.0A CN107308015A (en) | 2017-05-24 | 2017-05-24 | A kind of preparation method of effervesce toothpaste |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107308015A true CN107308015A (en) | 2017-11-03 |
Family
ID=60181519
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710371033.0A Pending CN107308015A (en) | 2017-05-24 | 2017-05-24 | A kind of preparation method of effervesce toothpaste |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107308015A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002138055A (en) * | 2000-10-31 | 2002-05-14 | Nipro Corp | Intraoral quick disintegration type compression molding and its production method |
| CN1771902A (en) * | 2005-11-04 | 2006-05-17 | 山东师范大学 | Multifunctional health toothpaste and its production process |
| CN106361588A (en) * | 2016-10-27 | 2017-02-01 | 陆腾蛟 | Tooth cleaning product and production device and process |
-
2017
- 2017-05-24 CN CN201710371033.0A patent/CN107308015A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002138055A (en) * | 2000-10-31 | 2002-05-14 | Nipro Corp | Intraoral quick disintegration type compression molding and its production method |
| CN1771902A (en) * | 2005-11-04 | 2006-05-17 | 山东师范大学 | Multifunctional health toothpaste and its production process |
| CN106361588A (en) * | 2016-10-27 | 2017-02-01 | 陆腾蛟 | Tooth cleaning product and production device and process |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2720001C2 (en) | On-site cleaning method, as well as system and composition for this purpose | |
| CN109609290A (en) | Cleaning agent and cleaning method are used after a kind of glass polishing | |
| CN101205509A (en) | Inorganic abradant cleaning paste | |
| CN1271267A (en) | Buccodental formulation comprising substantially amorphous cellulose nanofibrils | |
| CN107308015A (en) | A kind of preparation method of effervesce toothpaste | |
| CA2179317A1 (en) | Tooth whitening preparations | |
| CN105925401A (en) | Environment-friendly floor cleaning powder and production method thereof | |
| CN105505642A (en) | Water-saving car washing method | |
| CN105012222A (en) | Toothpaste composition by taking biologic cellulose nano powder as abrasive and preparation method | |
| CN105543001B (en) | A kind of duck hatching egg cleaning agent and its preparation method and application | |
| CN107597736A (en) | A kind of table glass turnplate greasy dirt flushing-free cleaning rubber implementation tool | |
| CN110547977B (en) | Oral care composition containing baking soda as well as preparation method and application thereof | |
| CN105695130B (en) | A kind of seamless neutral cleansing cream of sanitary equipment and preparation method thereof | |
| CN1476323A (en) | Method for preparing toothpaste using particular sorbitol syrup, and sorbitol syrup | |
| CN107892998A (en) | A kind of washing powder of strong dirt-removing stain | |
| CN106701373A (en) | Tea set bio-enzyme degerming cleaner and preparation method and application thereof | |
| CN102179384B (en) | Physical method for cleaning inner cavity of power coating extruder | |
| CN109106612B (en) | A kind of toothpaste discoloration friction particle and preparation method thereof | |
| CN109679780A (en) | One kind is exempted to wipe seamless car washing liquid entirely | |
| CA2204258A1 (en) | Glycolipid/mpg gels | |
| CN101429318B (en) | Grinding and wiping block rich in watersoluble polyvinyl alcohol and method of producing the same | |
| CN106311664B (en) | A kind of engine cylinder cover cleaning method | |
| CN100558873C (en) | A kind of fruit rust cleaning agent and using method thereof | |
| KR20120087450A (en) | Instantaneous cleanser for vehicle | |
| CN104148328A (en) | Method for cleaning pharmaceutical tablet mold |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171103 |