CN107307922A - The preparation method that a kind of human body is implanted into filler particles - Google Patents

The preparation method that a kind of human body is implanted into filler particles Download PDF

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Publication number
CN107307922A
CN107307922A CN201710547555.1A CN201710547555A CN107307922A CN 107307922 A CN107307922 A CN 107307922A CN 201710547555 A CN201710547555 A CN 201710547555A CN 107307922 A CN107307922 A CN 107307922A
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CN
China
Prior art keywords
mould
human body
silica gel
medical material
filler particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710547555.1A
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Chinese (zh)
Inventor
刘志光
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201710547555.1A priority Critical patent/CN107307922A/en
Publication of CN107307922A publication Critical patent/CN107307922A/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
    • B29C45/0001—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor characterised by the choice of material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001—Designing or manufacturing processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2083/00—Use of polymers having silicon, with or without sulfur, nitrogen, oxygen, or carbon only, in the main chain, as moulding material
    • B29K2083/005—LSR, i.e. liquid silicone rubbers, or derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Manufacturing & Machinery (AREA)
  • Mechanical Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

The present invention relates to the preparation method that a kind of human body is implanted into filler particles, including：Full-automatic liquid state silica gel injection moulding machine is linked together with mould by pipeline clamp joint；Take in the medical material for meeting implantation human body standard, the charge chute for being added to full-automatic liquid state silica gel injection moulding machine, mould is warmed to 150 200 DEG C；Full-automatic liquid state silica gel injection moulding machine is started, medical material is expelled in the mould of heating, medical material completes addition curing reaction in a mold, one-shot forming obtains circular granular；Open mould within 25 minutes after to be formed, the circular granular after shaping is taken out；Circular granular is fitted into polybag, sealed, after 25 30KGY gamma rays sterilizer is sterilized 30 minutes, packaging and storage produces human body implantation filler particles.During the filler particles implantation that the present invention makes, without cutting patient skin, as long as puncturing skin in operative site using medical thrust trochar, position needed for filler particles are implanted to.

Description

The preparation method that a kind of human body is implanted into filler particles
Technical field
The present invention relates to the preparation method that a kind of human body is implanted into filler particles, belong to medical equipment production field.
Background technology
All it is according to Surgery for human organ filling or cosmetic prosthesis in surgical procedure in present medical industry Position needs, and first processes solid shape, is then surgically implanted into human body.As artificial silica gel auricle, artificial silica gel chest enhancement prosthesis, Expanded rhinoplasty prosthese, stainless steel artificial femur are first-class；Also useful autologous cartilage, fat granules etc..Prior art percutaneous incision Skin is put into filling prosthesis and brings damage to patient body, and convalescence is longer, and surgery cost is higher.
The content of the invention
In order to solve the above-mentioned technical problem the present invention provides the preparation method that a kind of human body is implanted into filler particles, present invention system During the filler particles implantation of work, without cutting patient skin, as long as puncturing skin in operative site using medical thrust trochar, Position needed for particle is implanted to.
The technical scheme that the present invention solves above-mentioned technical problem is as follows：The preparation method that a kind of human body is implanted into filler particles, Including：
1) full-automatic liquid state silica gel injection moulding machine is linked together with mould by pipeline clamp joint；
2) medical material for meeting implantation human body standard is taken, the charge chute of full-automatic liquid state silica gel injection moulding machine is added to It is interior, mould is warmed to 150-200 DEG C；
3) full-automatic liquid state silica gel injection moulding machine is started, medical material is expelled in the mould of heating, medical material Addition curing reaction is completed in a mold, and one-shot forming obtains circular granular；
4) open mould within rear 2-5 minutes to be formed, the circular granular after shaping is taken out；
5) circular granular is fitted into polybag, sealed, sterilized 30 minutes by 25-30KGY gamma rays sterilizer Afterwards, packaging and storage, produces human body implantation filler particles.
On the basis of above-mentioned technical proposal, the present invention can also do following improvement.
Further, in step 1) in, the full-automatic liquid state silica gel injection moulding machine extensively celebrates machinery for Dongguan, Guangdong city to be had Limit company produces and commercially available GQ-85V-2S liquid silica gel injection machines.
Further, in step 1) in, the mould is the Bio-sil mould with diameter 1-3mm circular ports.
Further, in step 2) in, the medical material for meeting implantation human body standard, which refers to, meets the People's Republic of China (PRC) Medicine supervision general bureau is eaten in issue on 2 21st, 2017《Medicine equipment standard management method》Standard, it is adaptable to which three classes are passive to plant Entering property medicine equipment is produced and the medical material nontoxic to human body, preferably silica gel, varicosity, stainless steel or titanium alloy.
Using the beneficial effect of this step be selection meet implantation human body standard medical material, meet it is nontoxic to human body, Without requirement carcinogenic, without sensitization.
Further, in step 4) in, the spherical granules are hollow spherical granules or solid spherical granules.
The beneficial effects of the invention are as follows：
The human body made by this method is implanted into filler particles, with plasticity it is strong the characteristics of, can be according to the filling of operation The human body implantation filler particles of organ shape or the volume size at shaping position, appropriate injection different-diameter and unequal number amount.
This method make human body implantation filler particles, overcome when using conventional operation method be both needed to cut skin be put into Filling prosthesis, then again skin suture the drawbacks of.The implantation of this filler particles, without cutting skin, only need to use medical thrust Trochar punctures skin in operative site, position needed for particle is injected into.
The human body implantation filler particles that this method makes are mainly used in medical industry, are such as used for orthopedic a variety of hands Art：Rich temple, enlarge the bosom, pad the bridge of the nose and pad chin etc.；Or the filling for being recessed caused by human local tissue defect.
Embodiment
The principles and features of the present invention are described below, and the given examples are served only to explain the present invention, is not intended to limit Determine the scope of the present invention.
Embodiment 1
The preparation method of human body implantation filler particles of the present invention uses full-automatic liquid state silica gel injection moulding machine (Dongguan, Guangdong Guang Qing Machinery Co., Ltd.s of city produce and commercially available GQ-85V-2S liquid silica gels injection machine), once complete.With diameter 2mm circles The Bio-sil mould in shape hole is purchased from market.
The preparation method that a kind of human body is implanted into filler particles, including：
1) full-automatic liquid state silica gel injection moulding machine is linked together with mould by pipeline clamp joint, the mould For the Bio-sil mould with diameter 2mm circular ports；
2) the medical silica-gel material for meeting implantation human body standard is added to the charging of full-automatic liquid state silica gel injection moulding machine In groove, mould is warmed to 150-200 DEG C；
3) full application of brake liquid-state silicon gel injection moulding machine is started, it is medical in the mould medical silica-gel Material injection to heating Silica gel material completes addition curing reaction in a mold, and one-shot forming obtains circular granular；
4) open mould within rear 2-5 minutes to be formed, the circular silica gel particle of shaping is taken out；
5) circular silica gel particle is fitted into polybag, sealed, 30 are sterilized by 25-30KGY gamma rays sterilizer After minute, packaging and storage produces medical human implantation filling gel particle.
In use, medical human implantation filling gel particle can pass through medical special trochar, lead to after skin penetrating Cross trocar lumen and be sent to position needed for operation.
The foregoing is only presently preferred embodiments of the present invention, be not intended to limit the invention, it is all the present invention spirit and Within principle, any modification, equivalent substitution and improvements made etc. should be included in the scope of the protection.

Claims (6)

1. the preparation method that a kind of human body is implanted into filler particles, it is characterised in that including：
1) full-automatic liquid state silica gel injection moulding machine is linked together with mould by pipeline clamp joint；
2) take in the medical material for meeting implantation human body standard, the charge chute for being added to full-automatic liquid state silica gel injection moulding machine, Mould is warmed to 150-200 DEG C；
3) full-automatic liquid state silica gel injection moulding machine is started, medical material is expelled in the mould of heating, medical material is in mould Addition curing reaction is completed in tool, one-shot forming obtains circular granular；
4) open mould within rear 2-5 minutes to be formed, the circular granular after shaping is taken out；
5) circular granular is fitted into polybag, sealed, after 25-30KGY gamma rays sterilizer is sterilized 30 minutes, bag Load storehouse, produce human body implantation filler particles.
2. preparation method according to claim 1, it is characterised in that in step 1) in, the full-automatic liquid state silica gel note Molding machine is that Guang Qing Machinery Co., Ltd.s of Dongguan, Guangdong city produce and commercially available GQ-85V-2S liquid silica gel injection machines.
3. preparation method according to claim 1, it is characterised in that in step 1) in, the mould is with diameter 1- The Bio-sil mould of 3mm circular ports.
4. preparation method according to claim 1, it is characterised in that in step 2) in, it is described to meet implantation human body standard Medical material refer to meet the People's Republic of China (PRC) food medicine supervision general bureau on 2 21st, 2017 issue《Medicine equipment standard Management method》Standard, it is adaptable to the passive Implantable Medical Device production of three classes and the medical material nontoxic to human body.
5. preparation method according to claim 4, it is characterised in that the medical material refer to silica gel, varicosity, stainless steel or Titanium alloy.
6. preparation method according to claim 1, it is characterised in that in step 4) in, the spherical granules are hollow Spherical granules or solid spherical granules.
CN201710547555.1A 2017-07-06 2017-07-06 The preparation method that a kind of human body is implanted into filler particles Pending CN107307922A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710547555.1A CN107307922A (en) 2017-07-06 2017-07-06 The preparation method that a kind of human body is implanted into filler particles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710547555.1A CN107307922A (en) 2017-07-06 2017-07-06 The preparation method that a kind of human body is implanted into filler particles

Publications (1)

Publication Number Publication Date
CN107307922A true CN107307922A (en) 2017-11-03

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108790027A (en) * 2018-05-23 2018-11-13 上海蓓蕊医疗科技有限公司 A kind of pessary production technology
CN110547843A (en) * 2019-08-14 2019-12-10 杭州山友医疗器械有限公司 Umbilical cord clamp and processing technology thereof
CN112936732A (en) * 2021-02-05 2021-06-11 武汉磁济科技有限公司 Thermoplastic molding method of implanted flexible magnetic control bladder pump

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1751865A (en) * 2004-09-24 2006-03-29 埃姆斯化学股份公司 Injection molding method for manufacturing plastic parts
CN1903383A (en) * 2004-07-26 2007-01-31 株式会社Gc Bioabsorbable polymeric granular porous bone filling material and production method thereof
CN101857417A (en) * 2009-04-09 2010-10-13 黄兆龙 Manufacturing method of light weight aggregate
CN103120603A (en) * 2011-11-18 2013-05-29 生物合成物有限公司 Mould mat for producing bone cement pellets
CN104147640A (en) * 2013-05-16 2014-11-19 吴学森 Poly-d-lactic acid micro-nano particle as cosmetic and plastic filler and preparation method thereof
US20140378549A1 (en) * 2006-02-06 2014-12-25 Merz North America, Inc. Implantation compositions for use in tissue augmentation
US20150126615A1 (en) * 2013-11-05 2015-05-07 Tepha, Inc. Compositions and devices of poly-4-hydroxybutyrate
CN105228804A (en) * 2013-05-13 2016-01-06 宝洁公司 There is the low constant voltage adapted to injection system of the mold cavity of position changeable
CN105658251A (en) * 2013-08-09 2016-06-08 定位疗法有限公司 Composition and delivery system
US20160193368A1 (en) * 2009-12-15 2016-07-07 Incept, Llc Implants and biodegradable tissue markers

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1903383A (en) * 2004-07-26 2007-01-31 株式会社Gc Bioabsorbable polymeric granular porous bone filling material and production method thereof
CN1751865A (en) * 2004-09-24 2006-03-29 埃姆斯化学股份公司 Injection molding method for manufacturing plastic parts
US20140378549A1 (en) * 2006-02-06 2014-12-25 Merz North America, Inc. Implantation compositions for use in tissue augmentation
CN101857417A (en) * 2009-04-09 2010-10-13 黄兆龙 Manufacturing method of light weight aggregate
US20160193368A1 (en) * 2009-12-15 2016-07-07 Incept, Llc Implants and biodegradable tissue markers
CN103120603A (en) * 2011-11-18 2013-05-29 生物合成物有限公司 Mould mat for producing bone cement pellets
CN105228804A (en) * 2013-05-13 2016-01-06 宝洁公司 There is the low constant voltage adapted to injection system of the mold cavity of position changeable
CN104147640A (en) * 2013-05-16 2014-11-19 吴学森 Poly-d-lactic acid micro-nano particle as cosmetic and plastic filler and preparation method thereof
CN105658251A (en) * 2013-08-09 2016-06-08 定位疗法有限公司 Composition and delivery system
US20150126615A1 (en) * 2013-11-05 2015-05-07 Tepha, Inc. Compositions and devices of poly-4-hydroxybutyrate

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108790027A (en) * 2018-05-23 2018-11-13 上海蓓蕊医疗科技有限公司 A kind of pessary production technology
CN110547843A (en) * 2019-08-14 2019-12-10 杭州山友医疗器械有限公司 Umbilical cord clamp and processing technology thereof
CN110547843B (en) * 2019-08-14 2023-09-29 杭州山友医疗器械有限公司 Umbilical cord clamp and processing technology thereof
CN112936732A (en) * 2021-02-05 2021-06-11 武汉磁济科技有限公司 Thermoplastic molding method of implanted flexible magnetic control bladder pump
CN112936732B (en) * 2021-02-05 2022-03-08 武汉磁济科技有限公司 Thermoplastic molding method of implanted flexible magnetic control bladder pump

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Application publication date: 20171103