CN107281388A - Compound dendrobium huoshanense preparation, concentration water-honeyed pill for health care and preparation method thereof - Google Patents

Compound dendrobium huoshanense preparation, concentration water-honeyed pill for health care and preparation method thereof Download PDF

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CN107281388A
CN107281388A CN201710535979.6A CN201710535979A CN107281388A CN 107281388 A CN107281388 A CN 107281388A CN 201710535979 A CN201710535979 A CN 201710535979A CN 107281388 A CN107281388 A CN 107281388A
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parts
preparation
health care
dendrobium huoshanense
water
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戴亚峰
尚亮亮
许磊
张兴东
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JIUXIANZUN HUOSHAN DENDROBIUM Co Ltd
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JIUXIANZUN HUOSHAN DENDROBIUM Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8984Dendrobium
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
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    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
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    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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Abstract

The present invention discloses a kind of compound dendrobium huoshanense preparation for health care, includes the raw material of following parts by weight:30 40 parts of Dendrobidium huoshanness, 15 25 parts of the Radix Astragali, 15 25 parts of Radix Codonopsis, 5 15 parts of dateplum persimmon, 20 30 parts of walnut kernel, 10 15 parts of refined honey.Water-honeyed pill and preparation method thereof is concentrated invention additionally discloses a kind of compound dendrobium huoshanense for health care.The advantage of the invention is that:(1) concise in technology, makes simple, the nutrition leak of Dendrobidium huoshanness is few;(2) impurity is few, and various active ingredients are easier to absorb, and each active ingredient comprehensive utilization ratio is high;(3) dissolution rate height, the dissolution rate of preparation are fast;(4) by the way that Dendrobidium huoshanness and other above-mentioned each Chinese medicines are mixed, all medicines complement each other with using;Both made a distinction between the important and the lesser one, and coordinated tight, curative effect can be improved again, and be difficult to trigger other lesions, Small side effects can reach significant health-care effect.

Description

Compound dendrobium huoshanense preparation, concentration water-honeyed pill for health care and preparation method thereof
Technical field
The present invention relates to Chinese herbal medicine manufacture field, more particularly, to the compound dendrobium huoshanense preparation of health care, condensed water honey Ball and preparation method thereof.
Background technology
Dendrobidium huoshanness is orchid Dendrobium huoshanense C.Z.Tang et S.J. (Cheng), is 《Anhui Province's prepared slices of Chinese crude drugs concocted specification》Kind is included, medicinal effects are stem that is fresh or drying, mainly containing dendrobium polysaccharide, the stem of noble dendrobium The bioactive substances such as alkali, dendramine, nobilonine, dendroxine, dendrine, 6-hydroxydendroxine.Dendrobidium huoshanness maple bucket Can be for tea or as Baoshang material, as high-class healthy product, to chronic fatigue syndrome, tuberculosis, coronary heart disease, nephrosis, Chronic Liver The diseases such as disease, hypertension, high fat of blood, diabetes, chronic gastropathy, dry syndrome, cancer have definite curative effect and conditioning rehabilitation Effect, and can strengthen immunity of organisms, anti-oxidant, anti-aging, to excessive drinking and smoking, overwork, night life excessively, use ophthalmically acceptable brain Excessively, the weak power of hoarseness, mouth parched and tongue scorched, age declines, the rehabilitation such as the deficiency of Yin has special efficacy.
With social development, operating pressure increase, aging population is aggravated, and people are all the more obvious to the demand of health, with Dendrobidium huoshanness is that high-class healthy product and Chinese patent drug that raw material is produced are also more and more.
When directly being taken due to Dendrobidium huoshanness in medicinal material form, its utilization rate of active components is not high, existing Dendrobidium huoshanness Several middle forms such as maple bucket are usually processed into occur, it is then directly soaked.However, the Dendrobidium huoshanness dry product of this maple bucket shape formula, Manufacturing process is complicated, dissolution rate is low, dissolution rate is slow, bioavilability is low, nutrient loss is high, is unfavorable for rare medicinal material The utilization of resources.
Therefore, at present be badly in need of one kind prepare simply, dissolution rate height, dissolution rate is fast, bioavilability is high, nutritional ingredient stream Lose few for compound dendrobium huoshanense preparation of health care and preparation method thereof.
The content of the invention
It is an object of the invention to provide one kind prepare simply, dissolution rate is high, dissolution rate is fast, bioavilability is high, battalion Support the few compound dendrobium huoshanense preparation for being used for health care of ingredients from lossing, concentrate water-honeyed pill and preparation method thereof.
The present invention realizes above-mentioned technique effect by following technological means:A kind of compound dendrobium huoshanense system for health care Agent, includes the raw material of following parts by weight:30-40 parts of Dendrobidium huoshanness, 15-25 parts of the Radix Astragali, 15-25 parts of Radix Codonopsis, 5-15 parts of dateplum persimmon, 20-30 parts of walnut kernel, 10-15 parts of refined honey.
Preferably, the raw material of following parts by weight is included:Include the raw material of following parts by weight:34 parts of Dendrobidium huoshanness, it is yellow 16 parts of stilbene, 17 parts of Radix Codonopsis, 8 parts of dateplum persimmon, 25 parts of walnut kernel, 11 parts of refined honey.
Preferably, the raw material of following parts by weight is included:Include the raw material of following parts by weight:35 parts of Dendrobidium huoshanness, it is yellow 15 parts of stilbene, 15 parts of Radix Codonopsis, 10 parts of dateplum persimmon, 25 parts of walnut kernel, 12 parts of refined honey.
Preferably, the raw material of following parts by weight is included:38 parts of Dendrobidium huoshanness, 20 parts of the Radix Astragali, 20 parts of Radix Codonopsis, dateplum persimmon 13 Part, 28 parts of walnut kernel, 14 parts of refined honey.
The invention also discloses a kind of concentration water-honeyed pill using the above-mentioned compound dendrobium huoshanense preparation for health care.
The invention also discloses a kind of method for preparing the above-mentioned compound dendrobium huoshanense concentration water-honeyed pill for health care, including Following steps:
(1) Radix Astragali, Radix Codonopsis and dateplum persimmon of above-mentioned parts by weight are subjected to coarse crushing, to 60-80 mesh;
(2) by the raw material of gained in step (1), suitable quantity of water is added, it is 1 to make solid-liquid ratio:(9-11), carries out ultrasonic water extraction Take, carry out 2-4 times;
(3) by the Dendrobidium huoshanness of the above-mentioned parts by weight after 110-120 DEG C of steam sterilizing, the ring in (- 30)-(- 25) DEG C Under border, ultramicro grinding is carried out, Dendrobidium huoshanness juice is obtained;
(4) the Dendrobidium huoshanness juice after crushing the extract solution and step (3) of gained in step (2) is well mixed, centrifugation Afterwards, leave and take filtrate, remove insoluble matter;
(5) by the mixed liquor of gained in step (4), negative pressure concentration is carried out, solid content 10%-20% is concentrated into;
(6) by the walnut kernel of the above-mentioned parts by weight after 110-120 DEG C of steam sterilizing, the environment in (- 30)-(- 25) DEG C Under, ultramicro grinding is carried out, walnut kernel Ultramicro-powder is obtained;
(7) gained walnut kernel Ultramicro-powder is auxiliary material using in step (6), and gained concentrate enters as binding agent using in step (5) Row one-step palletizing, obtains dry powder;
(8) 5%-10% water is added in the refined honey of above-mentioned parts by weight, then is added into gained dry powder in step (7) In, general ball is dried, and produces compound dendrobium huoshanense concentration water-honeyed pill.
Preferably, when ultrasonic water extraction is carried out in the step (2), ultrasonic power 68%-72%, Extracting temperature 60-70 DEG C, extraction time 40-60min.
Preferably, centrifuged in the step (4) using tube centrifuge.
Preferably, insoluble matter is specially crude fibre in the step (4).
Preferably, when carrying out negative pressure concentration in the step (5), the condition that negative pressure is met is:Negative pressure (- 0.08)-(- 0.07) Mpa, 60-70 DEG C of temperature.
Effect of each raw material of the present invention:
Dendrobidium huoshanness:Hawk relieving sore-throat, nourishing Yin and moistening lung, nourishing the stomach to improve the production of body fluid, brain nourishing and eyesight improving, liver protection calming heart, heat-clearing and fire-reducing, tonifying five zang organs Consumptive disease, macrobiosis of making light of one's life by commiting suicide.
The Radix Astragali:Invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation.For treatment deficiency of vital energy weak, anorexia and loose stool, the sinking of qi of middle-jiao, Rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, ulcer is difficult to burst, burst for a long time and does not holds back, blood deficiency chlorosis, Heat Diabetes.
Radix Codonopsis:Tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung.For spleen and lung weakness, shortness of breath palpitations, anorexia and loose stool, virtual asthma cough, interior heat disappears Yearningly.
Dateplum persimmon:Tonifying middle-Jiao and Qi, blood-nourishing is calmed the nerves, improving eyesight.For anaemia, decrease of platelet, hepatitis is weak, insomnia.
Walnut kernel:Kidney tonifying, warm lung, ease constipation.For soreness and weakness of waist and knees, impotence and seminal emission, the cold of insufficiency type, which is breathed heavily, coughs, constipation.
Refined honey:Synergy is played with medicine, strengthens curative effect of medication;Removing toxic substances, mitigation pharmaceutical properties;Flavoring is rectified smelly.
The advantage of the present invention compared with prior art is:
(1) concise in technology, makes simple, the nutrition leak of Dendrobidium huoshanness is few;
(2) impurity is few, and various active ingredients are easier to absorb, and each active ingredient comprehensive utilization ratio is high;
(3) dissolution rate height, the dissolution rate of preparation are fast;
(4) by the way that Dendrobidium huoshanness and other above-mentioned each Chinese medicines are mixed, all medicines complement each other with using;Both made a distinction between the important and the lesser one, Coordinate tight, curative effect can be improved again, and be difficult to trigger other lesions, Small side effects can reach significant health-care effect.
Brief description of the drawings
Fig. 1 is the flow chart for the preparation method that the compound dendrobium huoshanense for health care in embodiment 7-9 concentrates water-honeyed pill.
Embodiment
Embodiments of the invention are elaborated below, the present embodiment is carried out lower premised on technical solution of the present invention Implement, give detailed embodiment and specific operating process, but protection scope of the present invention is not limited to following implementations Example.
Embodiment 1
A kind of compound dendrobium huoshanense preparation for health care, includes the raw material of following parts by weight:30 parts of Dendrobidium huoshanness, it is yellow 15 parts of stilbene, 15 parts of Radix Codonopsis, 5 parts of dateplum persimmon, 20 parts of walnut kernel, 10 parts of refined honey.
Embodiment 2
A kind of compound dendrobium huoshanense preparation for health care, includes the raw material of following parts by weight:40 parts of Dendrobidium huoshanness, it is yellow 25 parts of stilbene, 25 parts of Radix Codonopsis, 15 parts of dateplum persimmon, 30 parts of walnut kernel, 15 parts of refined honey.
Embodiment 3
A kind of compound dendrobium huoshanense preparation for health care, includes the raw material of following parts by weight:34 parts of Dendrobidium huoshanness, it is yellow 16 parts of stilbene, 17 parts of Radix Codonopsis, 8 parts of dateplum persimmon, 25 parts of walnut kernel, 11 parts of refined honey.
Embodiment 4
A kind of compound dendrobium huoshanense preparation for health care, includes the raw material of following parts by weight:35 parts of Dendrobidium huoshanness, it is yellow 15 parts of stilbene, 15 parts of Radix Codonopsis, 10 parts of dateplum persimmon, 25 parts of walnut kernel, 12 parts of refined honey.
Embodiment 5
A kind of compound dendrobium huoshanense preparation for health care, includes the raw material of following parts by weight:38 parts of Dendrobidium huoshanness, it is yellow 20 parts of stilbene, 20 parts of Radix Codonopsis, 13 parts of dateplum persimmon, 28 parts of walnut kernel, 14 parts of refined honey.
Embodiment 6
A kind of compound dendrobium huoshanense for health care concentrates water-honeyed pill, and the compound Huoshan of health care is used in above-described embodiment The formula of stem of noble dendrobium preparation is made.
Embodiment 7
A kind of compound dendrobium huoshanense for health care concentrates the preparation method of water-honeyed pill, as shown in figure 1, including following step Suddenly:
(1) Radix Astragali, Radix Codonopsis and dateplum persimmon of above-mentioned parts by weight are subjected to coarse crushing, to 60 mesh;
(2) by the raw material of gained in step (1), suitable quantity of water is added, it is 1 to make solid-liquid ratio:9, carry out ultrasonic water and extract, ultrasound Power 68%, 60 DEG C of Extracting temperature, extraction time 40min is carried out 2 times;
(3) by the Dendrobidium huoshanness of the above-mentioned parts by weight after 110 DEG C of steam sterilizings, in the environment of -30 DEG C, ultra micro is carried out Crush, obtain Dendrobidium huoshanness juice;
(4) the Dendrobidium huoshanness juice after crushing the extract solution and step (3) of gained in step (2) is well mixed, and is used After tube centrifuge centrifugation, leave and take filtrate, remove crude fibre;
(5) by the mixed liquor of gained in step (4), negative pressure concentration is carried out, solid content 10% is concentrated into;Wherein, negative pressure is full Foot condition be:Negative pressure -0.08Mpa, temperature 60 C;
(6) by the walnut kernel of the above-mentioned parts by weight after 110-120 DEG C of steam sterilizing, in the environment of -30 DEG C, surpassed Crushing of Ultrafine, obtains walnut kernel Ultramicro-powder;
(7) gained walnut kernel Ultramicro-powder is auxiliary material using in step (6), and gained concentrate enters as binding agent using in step (5) Row one-step palletizing, obtains dry powder;
(8) 5% water is added in the refined honey of above-mentioned parts by weight, then is added into step (7) in gained dry powder, it is general Ball, is dried, and produces compound dendrobium huoshanense concentration water-honeyed pill.
Embodiment 8
A kind of compound dendrobium huoshanense for health care concentrates the preparation method of water-honeyed pill, as shown in figure 1, including following step Suddenly:
(1) Radix Astragali, Radix Codonopsis and dateplum persimmon of above-mentioned parts by weight are subjected to coarse crushing, to 80 mesh;
(2) by the raw material of gained in step (1), suitable quantity of water is added, it is 1 to make solid-liquid ratio:11, carry out ultrasonic water and extract, surpass Acoustical power 72%, 70 DEG C of Extracting temperature, extraction time 60min is carried out 4 times;
(3) by the Dendrobidium huoshanness of the above-mentioned parts by weight after 120 DEG C of steam sterilizings, in the environment of -25 DEG C, ultra micro is carried out Crush, obtain Dendrobidium huoshanness juice;
(4) the Dendrobidium huoshanness juice after crushing the extract solution and step (3) of gained in step (2) is well mixed, and is used After tube centrifuge centrifugation, leave and take filtrate, remove crude fibre;
(5) by the mixed liquor of gained in step (4), negative pressure concentration is carried out, solid content 20% is concentrated into;Wherein, negative pressure is full Foot condition be:Negative pressure -0.07Mpa, temperature 70 C;
(6) by the walnut kernel of the above-mentioned parts by weight after 120 DEG C of steam sterilizings, in the environment of -25 DEG C, Ultramicro-powder is carried out It is broken, obtain walnut kernel Ultramicro-powder;
(7) gained walnut kernel Ultramicro-powder is auxiliary material using in step (6), and gained concentrate enters as binding agent using in step (5) Row one-step palletizing, obtains dry powder;
(8) 10% water is added in the refined honey of above-mentioned parts by weight, then is added into step (7) in gained dry powder, General ball, is dried, and produces compound dendrobium huoshanense concentration water-honeyed pill.
Embodiment 9
A kind of compound dendrobium huoshanense for health care concentrates the preparation method of water-honeyed pill, as shown in figure 1, including following step Suddenly:
(1) Radix Astragali, Radix Codonopsis and dateplum persimmon of above-mentioned parts by weight are subjected to coarse crushing, to 70 mesh;
(2) by the raw material of gained in step (1), suitable quantity of water is added, it is 1 to make solid-liquid ratio:10, carry out ultrasonic water and extract, surpass Acoustical power 70%, 65 DEG C of Extracting temperature, extraction time 50min is carried out 3 times;
(3) by the Dendrobidium huoshanness of the above-mentioned parts by weight after 115 DEG C of steam sterilizings, in the environment of -28 DEG C, ultra micro is carried out Crush, obtain Dendrobidium huoshanness juice;
(4) the Dendrobidium huoshanness juice after crushing the extract solution and step (3) of gained in step (2) is well mixed, and is used After tube centrifuge centrifugation, leave and take filtrate, remove crude fibre;
(5) by the mixed liquor of gained in step (4), negative pressure concentration is carried out, solid content 10%-20% is concentrated into;Wherein, bear Pressure meet condition be:Negative pressure -0.075Mpa, 65 DEG C of temperature;
(6) by the walnut kernel of the above-mentioned parts by weight after 115 DEG C of steam sterilizings, in the environment of -28 DEG C, Ultramicro-powder is carried out It is broken, obtain walnut kernel Ultramicro-powder;
(7) gained walnut kernel Ultramicro-powder is auxiliary material using in step (6), and gained concentrate enters as binding agent using in step (5) Row one-step palletizing, obtains dry powder;
(8) 8% water is added in the refined honey of above-mentioned parts by weight, then is added into step (7) in gained dry powder, it is general Ball, is dried, and produces compound dendrobium huoshanense concentration water-honeyed pill.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention Any modifications, equivalent substitutions and improvements made within refreshing and principle etc., should be included in the scope of the protection.

Claims (10)

1. a kind of compound dendrobium huoshanense preparation for health care, it is characterised in that include the raw material of following parts by weight:Huoshan stone 30-40 parts of dry measure used in former times, 15-25 parts of the Radix Astragali, 15-25 parts of Radix Codonopsis, 5-15 parts of dateplum persimmon, 20-30 parts of walnut kernel, 10-15 parts of refined honey.
2. the compound dendrobium huoshanense preparation according to claim 1 for health care, it is characterised in that including following parts by weight Several raw materials:34 parts of Dendrobidium huoshanness, 16 parts of the Radix Astragali, 17 parts of Radix Codonopsis, 8 parts of dateplum persimmon, 25 parts of walnut kernel, 11 parts of refined honey.
3. the compound dendrobium huoshanense preparation according to claim 1 for health care, it is characterised in that including following parts by weight Several raw materials:35 parts of Dendrobidium huoshanness, 15 parts of the Radix Astragali, 15 parts of Radix Codonopsis, 10 parts of dateplum persimmon, 25 parts of walnut kernel, 12 parts of refined honey.
4. the compound dendrobium huoshanense preparation according to claim 1 for health care, it is characterised in that including following parts by weight Several raw materials:38 parts of Dendrobidium huoshanness, 20 parts of the Radix Astragali, 20 parts of Radix Codonopsis, 13 parts of dateplum persimmon, 28 parts of walnut kernel, 14 parts of refined honey.
5. a kind of condensed water honey of compound dendrobium huoshanense preparation for health care using as described in claim any one of 1-4 Ball.
6. the compound dendrobium huoshanense according to claim 5 for health care concentrates the preparation method of water-honeyed pill, its feature exists In comprising the following steps:
(1) Radix Astragali, Radix Codonopsis and dateplum persimmon of above-mentioned parts by weight are subjected to coarse crushing, to 60-80 mesh;
(2) by the raw material of gained in step (1), suitable quantity of water is added, it is 1 to make solid-liquid ratio:(9-11), carries out ultrasonic water and extracts, enter Row 2-4 times;
(3) by the Dendrobidium huoshanness of the above-mentioned parts by weight after 110-120 DEG C of steam sterilizing, in the environment of (- 30)-(- 25) DEG C, Ultramicro grinding is carried out, Dendrobidium huoshanness juice is obtained;
(4) the Dendrobidium huoshanness juice after crushing the extract solution and step (3) of gained in step (2) is well mixed, and after centrifugation, is stayed Take filtrate, remove insoluble matter;
(5) by the mixed liquor of gained in step (4), negative pressure concentration is carried out, solid content 10%-20% is concentrated into;
(6) by the walnut kernel of the above-mentioned parts by weight after 110-120 DEG C of steam sterilizing, in the environment of (- 30)-(- 25) DEG C, enter Row ultramicro grinding, obtains walnut kernel Ultramicro-powder;
(7) gained walnut kernel Ultramicro-powder is auxiliary material using in step (6), and gained concentrate carries out one as binding agent using in step (5) Step granulation, obtains dry powder;
(8) 5%-10% water is added in the refined honey of above-mentioned parts by weight, then is added into step (7) in gained dry powder, General ball, is dried, and produces compound dendrobium huoshanense concentration water-honeyed pill.
7. the compound dendrobium huoshanense according to claim 6 for health care concentrates the preparation method of water-honeyed pill, its feature exists In, when ultrasonic water extraction is carried out in the step (2), ultrasonic power 68%-72%, 60-70 DEG C of Extracting temperature, extraction time 40-60min。
8. the compound dendrobium huoshanense according to claim 6 for health care concentrates the preparation method of water-honeyed pill, its feature exists In the step (4) is middle to be centrifuged using tube centrifuge.
9. the compound dendrobium huoshanense according to claim 6 for health care concentrates the preparation method of water-honeyed pill, its feature exists In insoluble matter is specially crude fibre in the step (4).
10. the compound dendrobium huoshanense according to claim 6 for health care concentrates the preparation method of water-honeyed pill, its feature exists In when carrying out negative pressure concentration in the step (5), the condition that negative pressure is met is:Negative pressure (- 0.08)-(- 0.07) Mpa, temperature 60-70℃。
CN201710535979.6A 2017-07-04 2017-07-04 Compound dendrobium huoshanense preparation, concentration water-honeyed pill for health care and preparation method thereof Pending CN107281388A (en)

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