CN107280811A - 基于3d打印的金属骨小梁技术的骨界面处理方法 - Google Patents
基于3d打印的金属骨小梁技术的骨界面处理方法 Download PDFInfo
- Publication number
- CN107280811A CN107280811A CN201710464559.3A CN201710464559A CN107280811A CN 107280811 A CN107280811 A CN 107280811A CN 201710464559 A CN201710464559 A CN 201710464559A CN 107280811 A CN107280811 A CN 107280811A
- Authority
- CN
- China
- Prior art keywords
- bone
- metal
- bone trabecula
- joint prosthesis
- trabecula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000000988 bone and bone Anatomy 0.000 title claims abstract description 96
- 229910052751 metal Inorganic materials 0.000 title claims abstract description 47
- 239000002184 metal Substances 0.000 title claims abstract description 47
- 238000005516 engineering process Methods 0.000 title claims abstract description 25
- 238000010146 3D printing Methods 0.000 title claims abstract description 19
- 238000003672 processing method Methods 0.000 title claims abstract description 12
- 238000000034 method Methods 0.000 claims abstract description 26
- 238000005245 sintering Methods 0.000 claims abstract description 14
- 239000011148 porous material Substances 0.000 claims abstract description 5
- 150000002739 metals Chemical class 0.000 claims abstract description 4
- 229910001069 Ti alloy Inorganic materials 0.000 claims description 5
- 238000003801 milling Methods 0.000 claims description 5
- 238000005266 casting Methods 0.000 claims description 4
- 238000004372 laser cladding Methods 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 2
- 238000004513 sizing Methods 0.000 claims description 2
- 238000000576 coating method Methods 0.000 abstract description 20
- 239000011248 coating agent Substances 0.000 abstract description 15
- 238000002844 melting Methods 0.000 abstract description 5
- 230000008018 melting Effects 0.000 abstract description 5
- 239000007943 implant Substances 0.000 description 9
- 239000000463 material Substances 0.000 description 7
- 239000011159 matrix material Substances 0.000 description 5
- 238000012545 processing Methods 0.000 description 3
- 238000003466 welding Methods 0.000 description 3
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 2
- 230000000975 bioactive effect Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 210000004394 hip joint Anatomy 0.000 description 2
- 239000012943 hotmelt Substances 0.000 description 2
- 238000002513 implantation Methods 0.000 description 2
- 210000001503 joint Anatomy 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 238000007747 plating Methods 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 239000010936 titanium Substances 0.000 description 2
- 229910052719 titanium Inorganic materials 0.000 description 2
- 230000005526 G1 to G0 transition Effects 0.000 description 1
- 238000003854 Surface Print Methods 0.000 description 1
- 229910003087 TiOx Inorganic materials 0.000 description 1
- UELITFHSCLAHKR-UHFFFAOYSA-N acibenzolar-S-methyl Chemical compound CSC(=O)C1=CC=CC2=C1SN=N2 UELITFHSCLAHKR-UHFFFAOYSA-N 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003592 biomimetic effect Effects 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 230000002301 combined effect Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000005242 forging Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 239000011858 nanopowder Substances 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
- 238000007750 plasma spraying Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 229910052715 tantalum Inorganic materials 0.000 description 1
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 1
- HLLICFJUWSZHRJ-UHFFFAOYSA-N tioxidazole Chemical compound CCCOC1=CC=C2N=C(NC(=O)OC)SC2=C1 HLLICFJUWSZHRJ-UHFFFAOYSA-N 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30772—Apertures or holes, e.g. of circular cross section
- A61F2002/30784—Plurality of holes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2002/3097—Designing or manufacturing processes using laser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2002/30985—Designing or manufacturing processes using three dimensional printing [3DP]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00011—Metals or alloys
- A61F2310/00023—Titanium or titanium-based alloys, e.g. Ti-Ni alloys
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Geometry (AREA)
- Manufacturing & Machinery (AREA)
- Prostheses (AREA)
Abstract
一种基于3D打印的金属骨小梁技术的骨界面处理方法，其特征在于在人工关节假体界面上制备孔隙直径在300‑600微米金属骨小梁微孔层，所述金属骨小梁微孔层由激光熔覆3D打印机直接在人工关节界面上打印制备，或所述金属骨小梁微孔层先由3D打印机打印出骨小梁薄片，再应用烧结工艺将其结合到预制好的人工关节假体骨界面上。与现有技术相比，本发明采用的激光熔覆技术是对现有人工关节表面处理技术的一项革命性突破，为3D打印技术在人工关节假体骨界面技术领域的应用打下了基础，现国内外尚无同类技术产品。
Description
技术领域
本发明属于人工关节假体制备技术领域，具体涉及一种基于3D打印的金属骨小梁技术的骨界面处理方法。
背景技术
众所周知，通过植入假体构件以替换自然骨关节的一部分或全部来修复由于疾病或伤害而受损的骨关节。例如，髋关节的外科手术重建可能需要在股骨端部处植入以利用假体支承头替换自然股骨头的股骨假体构件，以及在经绞扩的髋臼腔或自然髋臼内植入以接纳假体支承头的假体髋臼杯。
已知一定范围的用于将假体固定到骨表面上或骨腔内的不同固定技术。此外，这些固定技术可相结合地使用。通常，通过使用从假体延伸到骨中的螺钉、钉子、丝线或类似的紧固件固定假体来提供机械固定。还已知的是向假体表面提供涂层，该涂层在植入时与骨相接触，或者紧邻骨，其中该涂层选择为用以促进骨整合。骨整合是指活骨与假体表面之间的直接结构和功能连接。
骨整合可由机械保持产生，由此骨向内生长到假体、特别是金属假体的表面特征中而将假体固定在骨上，或者可由生物活性保持产生，由此植入物涂覆有生物活性材料，该生物活性材料刺激骨形成而引起植入物与骨长合的化学连结。
对于诸多普遍在可植入假体内使用的金属 ( 例如钛或钛合金 ) 而言，会发生机械固定引起的骨整合。通过在假体与骨相接触的表面上设置拓扑特征如通气孔、槽缝和凹窝能够促进骨整合。不存在假体的化学保持并且这种保持取决于假体的表面积。
通过处理假体的表面部分以增加其表面积，例如蚀刻该表面，可促进通过机械固定的骨整合。已知对金属基底涂覆多孔涂层使得骨向内生长到孔内而在假体与骨之间形成牢固连结。多孔涂层可由在它们的接触点连结在一起的金属材料的多个小的分散颗粒组成，以在涂层中限定多个连接的间隙孔。
申请公布号 CN 103221000 A申请公布日 2013.07.24公开了一种多孔金属层至金属基体的电阻焊接技术，用于通过将整形假体的多孔金属层（22）电阻焊接至整型假体的在下面的金属基体（20）上而制造整形假体（10）的设备（100）和方法。电阻焊接工艺包括引导电流经过多孔层和基体，所述电流作为热量散发以引起材料的、尤其是沿着多孔层与基体之间分界面的软化和 / 或热熔。软化的和 / 或热熔的的材料在多孔层与基体之间的接触点处经受冶金结合以将多孔层牢固地固定到基体上。
申请公布号CN 105105875 A申请公布日2015.12.02公开了一种具有内生长功能的仿生人工髋关节，在股骨柄外表面制备了生物活性的多孔涂层，所述生物活性涂层 (6)采用烧结法、化学镀、电镀、等离子喷涂方法或高能粒子束成型法在股骨柄 (5) 表面制备具有生物活性的多孔涂层 ；生物活性涂层 (6) 从基底由里往外喷涂材料成分呈梯度变化；生物活性涂层 (6) 材料采用羟基磷灰石纳米粉末、生物活性玻璃粉末和氧化钛纳米粉末形成的复合材料或钛或钛合金或钽，生物活性涂层 (6) 材料的粉末粒径为30-100nm，生物活性涂层(6)的厚度为50-200μm ；生物活性涂层(6)的孔隙率为10-85％。
从上述现有技术可以看出，目前人工关节骨界面处理技术应用分别是喷涂和烧结两种工艺，由于技术难题原因，一直没能把3D打印的金属骨小梁技术应用到人工关节的骨界面应用中。
发明内容
为解决现有技术存在的上述技术缺陷，本发明的目的在于提供一种基于3D打印的金属骨小梁技术的骨界面处理方法。
为实现上述目的，本发明采用的技术方案：该基于3D打印的金属骨小梁技术的骨界面处理方法，其特征在于在人工关节假体界面上制备孔隙直径在300-600微米金属骨小梁微孔层，所述金属骨小梁微孔层由激光熔覆3D打印机直接在人工关节界面上打印制备，或所述金属骨小梁微孔层先由3D打印机打印出骨小梁薄片，再应用烧结工艺将其结合到预制好的人工关节假体骨界面上。
所述人工关节假体采用铸造或锻造技术制备出假体毛胚，再通过数控机床雕铣定型，最后通过激光溶覆技术在假体表面打印出金属骨小梁微孔。
所述烧结工艺是先铸造或锻造出人工关节假体毛胚，再通过数控机床雕铣出有卡槽的假体，将预先打印好的钛合金金属骨小梁薄片钳入假体卡槽，放入烧结设备中抽真空，再经800度右高温烧结而成。
所述金属骨小梁微孔层厚度为2-5mm。
优选的，所述金属骨小梁微孔层厚度为2mm。
采用上述技术方案的有益效果：该基于3D打印的金属骨小梁技术的骨界面处理方法是在人工关节假体骨界面上制备350-550微米金属骨小梁微孔层，金属骨小梁微孔层厚度为3-5mm，其厚度远远大于现有的喷涂方法制备的金属骨小梁微孔层厚度，大量的动物试验和临床试验证实应用3D打印的金属骨小梁植入体，当孔隙直径在350-550微米时骨长入效果最好，诱导或促进成骨细胞内生长的生物型固定相结合，结合面厚度为整个骨小梁的厚度，结合强度大，以保证假体服役期间的稳定性。满足强度和细胞内生长的要求，关节植入后依然能够维持原有骨的生物力学特征，而且最大限度的保存骨量，避免出现“应力遮挡”和假体松动。从而使人工关节假体与周围骨组织“生长”成为一体，缩短了假体坚强固定的时间，降低了假体松动下沉的并发症，延长了人工关节的使用寿命。由3D打印的金属骨小梁技术直接在人工关节假体骨界面上打印，有利于骨长入，是目前世界上最先进的人工关节界面处理技术，彻底颠覆现有人工关节假体界面处理技术。所述人工关节假体由铸造或锻造方法制备的金属假体，其抗疲劳强度大，能够提高假体的承重能力。
与现有技术相比，本发明采用的激光熔覆技术是对现有人工关节表面处理技术的一项革命性突破，为3D打印技术在人工关节假体骨界面技术领域的应用打下了基础，现国内外尚无同类技术产品。
附图说明
下面结合附图对本发明的具体实施例作进一步详细的说明。
图1为由激光熔覆3D打印机直接在人工关节界面上打印金属骨小梁微孔层图。
图2为通过数控机床雕铣出有卡槽的假体图。
图3为烧结工艺将其结合到预制好的人工关节假体骨界面图。
具体实施方式
如图1、2、3所示，该基于3D打印的金属骨小梁技术的骨界面处理方法，采用3D打印技术制备各种异型的人工关节假体，在人工关节假体界面上制备孔隙直径在300-600微米金属骨小梁微孔层2，所述金属骨小梁微孔层2由3D打印机直接在人工关节界面1上打印制备，或所述金属骨小梁微孔层2先由3D打印机打印出骨小梁薄片，再应用烧结工艺将其结合到预制好的人工关节假体骨界面上，通过烧结层3将骨小梁薄片与人工关节假体骨界面连接为牢固的一个整体。所述3D打印机为激光熔覆设备。所述人工关节假体采用铸造或锻造技术制备出假体毛胚，再通过数控机床雕铣定型，最后通过激光溶覆技术在假体表面打印出金属骨小梁微孔。所述烧结工艺是先铸造或锻造出人工关节假体毛胚，再通过数控机床雕铣出有卡槽的假体，将预先打印好的钛合金金属骨小梁薄片钳入假体卡槽4，放入烧结设备中抽真空，再经800度右高温烧结而成。
所述金属骨小梁微孔层厚度为2-5mm。优选的，所述金属骨小梁微孔层厚度为2mm。
以上借助具体实施例对本发明做了进一步描述，但是应该理解的是，这里具体的描述，不应理解为对本发明的实质和范围的限定，本领域内的普通技术人员在阅读本说明书后对上述实施例做出的各种修改，都属于本发明所保护的范围。
Claims (5)
1.一种基于3D打印的金属骨小梁技术的骨界面处理方法，其特征在于在人工关节假体界面上制备孔隙直径在300-600微米金属骨小梁微孔层，所述金属骨小梁微孔层由激光熔覆3D打印机直接在人工关节界面上打印制备，或所述金属骨小梁微孔层先由3D打印机打印出骨小梁薄片，再应用烧结工艺将其结合到预制好的人工关节假体骨界面上。
2.如权利要求1所述的基于3D打印的金属骨小梁技术的骨界面处理方法，其特征在于：所述人工关节假体采用铸造或锻造技术制备出假体毛胚，再通过数控机床雕铣定型，最后通过激光溶覆技术在假体表面打印出金属骨小梁微孔。
3.如权利要求1所述的基于3D打印的金属骨小梁技术的骨界面处理方法，其特征在于：所述烧结工艺是先铸造或锻造出人工关节假体毛胚，再通过数控机床雕铣出有卡槽的假体，将预先打印好的钛合金金属骨小梁薄片钳入假体卡槽，放入烧结设备中抽真空，再经800度右高温烧结而成。
4.如权利要求1所述的基于3D打印的金属骨小梁技术的骨界面处理方法，其特征在于：所述金属骨小梁微孔层厚度为2-5mm。
5.如权利要求4所述的基于3D打印的金属骨小梁技术的骨界面处理方法，其特征在于：所述金属骨小梁微孔层厚度为2mm。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710464559.3A CN107280811A (zh) | 2017-06-19 | 2017-06-19 | 基于3d打印的金属骨小梁技术的骨界面处理方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710464559.3A CN107280811A (zh) | 2017-06-19 | 2017-06-19 | 基于3d打印的金属骨小梁技术的骨界面处理方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107280811A true CN107280811A (zh) | 2017-10-24 |
Family
ID=60096688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710464559.3A Pending CN107280811A (zh) | 2017-06-19 | 2017-06-19 | 基于3d打印的金属骨小梁技术的骨界面处理方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107280811A (zh) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111281616A (zh) * | 2020-03-11 | 2020-06-16 | 北京市春立正达医疗器械股份有限公司 | 一种全髋金属杯假体及其制作方法 |
| CN111281617A (zh) * | 2020-03-11 | 2020-06-16 | 北京市春立正达医疗器械股份有限公司 | 一种3d打印假体及应用 |
| CN112022446A (zh) * | 2020-09-29 | 2020-12-04 | 北京市春立正达医疗器械股份有限公司 | 一种半骨盆假体 |
| CN112022444A (zh) * | 2020-09-29 | 2020-12-04 | 北京市春立正达医疗器械股份有限公司 | 一种骨小梁结构 |
| CN112022445A (zh) * | 2020-09-29 | 2020-12-04 | 北京市春立正达医疗器械股份有限公司 | 一种骨小梁结构及其应用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104000674A (zh) * | 2014-06-10 | 2014-08-27 | 张衣北 | 具柔韧性骨小梁结构椎间融合器 |
| CN106388976A (zh) * | 2016-04-11 | 2017-02-15 | 四川大学华西医院 | 3d打印仿骨小梁多孔承重增强金属假体 |
| CN106510904A (zh) * | 2016-12-12 | 2017-03-22 | 吴栋 | 一种人工关节股骨柄及其制备方法 |
-
2017
- 2017-06-19 CN CN201710464559.3A patent/CN107280811A/zh active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104000674A (zh) * | 2014-06-10 | 2014-08-27 | 张衣北 | 具柔韧性骨小梁结构椎间融合器 |
| CN106388976A (zh) * | 2016-04-11 | 2017-02-15 | 四川大学华西医院 | 3d打印仿骨小梁多孔承重增强金属假体 |
| CN106510904A (zh) * | 2016-12-12 | 2017-03-22 | 吴栋 | 一种人工关节股骨柄及其制备方法 |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111281616A (zh) * | 2020-03-11 | 2020-06-16 | 北京市春立正达医疗器械股份有限公司 | 一种全髋金属杯假体及其制作方法 |
| CN111281617A (zh) * | 2020-03-11 | 2020-06-16 | 北京市春立正达医疗器械股份有限公司 | 一种3d打印假体及应用 |
| CN111281616B (zh) * | 2020-03-11 | 2023-08-04 | 北京市春立正达医疗器械股份有限公司 | 一种全髋金属杯假体及其制作方法 |
| CN112022446A (zh) * | 2020-09-29 | 2020-12-04 | 北京市春立正达医疗器械股份有限公司 | 一种半骨盆假体 |
| CN112022444A (zh) * | 2020-09-29 | 2020-12-04 | 北京市春立正达医疗器械股份有限公司 | 一种骨小梁结构 |
| CN112022445A (zh) * | 2020-09-29 | 2020-12-04 | 北京市春立正达医疗器械股份有限公司 | 一种骨小梁结构及其应用 |
| CN112022444B (zh) * | 2020-09-29 | 2022-03-25 | 北京市春立正达医疗器械股份有限公司 | 一种骨小梁结构 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107280811A (zh) | 基于3d打印的金属骨小梁技术的骨界面处理方法 | |
| US9775711B2 (en) | Rapid manufacturing of porous metal prostheses | |
| JP4444587B2 (ja) | 多孔性金属層を金属の基体に付着させる方法 | |
| CN105877874B (zh) | 仿生设计类骨多孔骨制品及其制备方法 | |
| US8191760B2 (en) | Method for attaching porous metal layer to a metal substrate | |
| US4168326A (en) | Prosthesis parts provided with a coating of a bio-active material, process of making same, and method of using them for bone replacement | |
| JP6916290B2 (ja) | モジュール式増強コンポーネント | |
| EP1290992B1 (en) | Acetabular cup | |
| US10898335B1 (en) | Hip implant with porous body | |
| EP1344537B1 (en) | Porous metallic scaffold for tissue ingrowth | |
| JPS61106149A (ja) | 骨組織凝着促進部材，骨植込み部材および製法 | |
| EP2836166B1 (en) | Prosthetic element for bone extremities such as fingers or toes, or for teeth, and corresponding production method | |
| KR20120112670A (ko) | 보철물 | |
| Singh et al. | Design and development of 3D printing assisted microwave sintering of elbow implant with biomechanical properties similar tohuman elbow | |
| McTighe et al. | 14 Metallic Alloys in Total Hip Arthroplasty | |
| US20150081028A1 (en) | Adaptor for modular joint prostheses | |
| CN109771101A (zh) | 一种用于松质骨缺损修复的金属仿生骨小梁及其制备方法 | |
| CN219439565U (zh) | 一种3d打印的宠物髋关节假体 | |
| EP4241738A1 (en) | Non-polygonal porous structure | |
| US20210178015A1 (en) | Method to produce a prosthetic component, and prosthetic component thus produced | |
| CN113209381A (zh) | 一种人工膝关节骰骨髁及其制备方法 | |
| CN117257528A (zh) | 髋臼假体、髋臼假体制备方法和关节假体 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171024 |