CN107261143A - 一种纳米复合材料的合成方法和应用 - Google Patents
一种纳米复合材料的合成方法和应用 Download PDFInfo
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- CN107261143A CN107261143A CN201710573427.4A CN201710573427A CN107261143A CN 107261143 A CN107261143 A CN 107261143A CN 201710573427 A CN201710573427 A CN 201710573427A CN 107261143 A CN107261143 A CN 107261143A
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- sulfanilamide
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- 239000000463 material Substances 0.000 title claims abstract description 53
- 239000002114 nanocomposite Substances 0.000 title claims abstract description 38
- 238000010189 synthetic method Methods 0.000 title claims abstract description 9
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical compound NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 claims abstract description 140
- 229940124530 sulfonamide Drugs 0.000 claims abstract description 140
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 52
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- 229910052751 metal Inorganic materials 0.000 claims abstract description 8
- VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical compound [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 claims abstract description 7
- 229910001447 ferric ion Inorganic materials 0.000 claims abstract description 7
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 22
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 21
- 239000008367 deionised water Substances 0.000 claims description 19
- 229910021641 deionized water Inorganic materials 0.000 claims description 19
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims description 18
- 238000006243 chemical reaction Methods 0.000 claims description 18
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- RUTXIHLAWFEWGM-UHFFFAOYSA-H iron(3+) sulfate Chemical compound [Fe+3].[Fe+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O RUTXIHLAWFEWGM-UHFFFAOYSA-H 0.000 claims description 2
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- DCPMPXBYPZGNDC-UHFFFAOYSA-N hydron;methanediimine;chloride Chemical compound Cl.N=C=N DCPMPXBYPZGNDC-UHFFFAOYSA-N 0.000 claims 1
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- 239000003643 water by type Substances 0.000 description 9
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 7
- 229910052760 oxygen Inorganic materials 0.000 description 7
- 239000001301 oxygen Substances 0.000 description 7
- HHDUMDVQUCBCEY-UHFFFAOYSA-N 4-[10,15,20-tris(4-carboxyphenyl)-21,23-dihydroporphyrin-5-yl]benzoic acid Chemical compound OC(=O)c1ccc(cc1)-c1c2ccc(n2)c(-c2ccc(cc2)C(O)=O)c2ccc([nH]2)c(-c2ccc(cc2)C(O)=O)c2ccc(n2)c(-c2ccc(cc2)C(O)=O)c2ccc1[nH]2 HHDUMDVQUCBCEY-UHFFFAOYSA-N 0.000 description 6
- MHABMANUFPZXEB-UHFFFAOYSA-N O-demethyl-aloesaponarin I Natural products O=C1C2=CC=CC(O)=C2C(=O)C2=C1C=C(O)C(C(O)=O)=C2C MHABMANUFPZXEB-UHFFFAOYSA-N 0.000 description 6
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- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 3
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- 231100000331 toxic Toxicity 0.000 description 2
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- PXEZTIWVRVSYOK-UHFFFAOYSA-N 2-(3,6-diacetyloxy-2,7-dichloro-9h-xanthen-9-yl)benzoic acid Chemical compound C1=2C=C(Cl)C(OC(=O)C)=CC=2OC2=CC(OC(C)=O)=C(Cl)C=C2C1C1=CC=CC=C1C(O)=O PXEZTIWVRVSYOK-UHFFFAOYSA-N 0.000 description 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 description 1
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- 229940113088 dimethylacetamide Drugs 0.000 description 1
- 229910001882 dioxygen Inorganic materials 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
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- 239000000446 fuel Substances 0.000 description 1
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- 230000036541 health Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
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- 238000004519 manufacturing process Methods 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
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- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004899 motility Effects 0.000 description 1
- BXGTVNLGPMZLAZ-UHFFFAOYSA-N n'-ethylmethanediimine;hydrochloride Chemical compound Cl.CCN=C=N BXGTVNLGPMZLAZ-UHFFFAOYSA-N 0.000 description 1
- 239000005416 organic matter Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0076—PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
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CN201710573427.4A CN107261143B (zh) | 2017-07-14 | 2017-07-14 | 一种纳米复合材料的合成方法和应用 |
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CN201710573427.4A CN107261143B (zh) | 2017-07-14 | 2017-07-14 | 一种纳米复合材料的合成方法和应用 |
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CN107261143B CN107261143B (zh) | 2020-07-10 |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108939072A (zh) * | 2018-07-13 | 2018-12-07 | 湖北大学 | 一种用于肿瘤光动力治疗的纳米载体及其制备方法 |
CN114099677A (zh) * | 2022-01-26 | 2022-03-01 | 广东工业大学 | 一种铁酸铜纳米材料的制备方法及应用 |
CN114891235A (zh) * | 2022-05-24 | 2022-08-12 | 暨南大学 | 多配体功能化复合纳米材料及其制备方法与应用 |
CN117384389A (zh) * | 2023-10-25 | 2024-01-12 | 广州医科大学附属第一医院(广州呼吸中心) | 一种纳米材料及其制备和应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102961337A (zh) * | 2012-12-14 | 2013-03-13 | 哈尔滨工业大学 | 靶向复合纳米粒子的制备方法 |
US20150284416A1 (en) * | 2015-06-16 | 2015-10-08 | Suzhou M-Conj Biotech Co., Ltd | Novel linkers for conjugation of cell-binding molecules |
-
2017
- 2017-07-14 CN CN201710573427.4A patent/CN107261143B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102961337A (zh) * | 2012-12-14 | 2013-03-13 | 哈尔滨工业大学 | 靶向复合纳米粒子的制备方法 |
US20150284416A1 (en) * | 2015-06-16 | 2015-10-08 | Suzhou M-Conj Biotech Co., Ltd | Novel linkers for conjugation of cell-binding molecules |
Non-Patent Citations (2)
Title |
---|
JINGJING LIU等: ""Nanoscale metal organic frameworks for combined photodynamic &radiation therapy in cancer treatment"", 《BIOMATERIALS》 * |
杨江峰等: ""脱氧剂Fe-MOF-74的制备及氧气吸附失活规律"", 《化工学报》 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108939072A (zh) * | 2018-07-13 | 2018-12-07 | 湖北大学 | 一种用于肿瘤光动力治疗的纳米载体及其制备方法 |
CN114099677A (zh) * | 2022-01-26 | 2022-03-01 | 广东工业大学 | 一种铁酸铜纳米材料的制备方法及应用 |
CN114891235A (zh) * | 2022-05-24 | 2022-08-12 | 暨南大学 | 多配体功能化复合纳米材料及其制备方法与应用 |
CN117384389A (zh) * | 2023-10-25 | 2024-01-12 | 广州医科大学附属第一医院(广州呼吸中心) | 一种纳米材料及其制备和应用 |
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CN107261143B (zh) | 2020-07-10 |
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Application publication date: 20171020 Assignee: Wuhan chengxianghui science and Technology Center Assignor: Hubei University Contract record no.: X2023420000295 Denomination of invention: A Synthesis Method and Application of Nanocomposite Materials Granted publication date: 20200710 License type: Common License Record date: 20230817 Application publication date: 20171020 Assignee: Wuhan Yucheng Technology Center Assignor: Hubei University Contract record no.: X2023420000294 Denomination of invention: A Synthesis Method and Application of Nanocomposite Materials Granted publication date: 20200710 License type: Common License Record date: 20230817 Application publication date: 20171020 Assignee: Wuhan Boya Technology Center Assignor: Hubei University Contract record no.: X2023420000293 Denomination of invention: A Synthesis Method and Application of Nanocomposite Materials Granted publication date: 20200710 License type: Common License Record date: 20230817 |
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