CN107261092A - A kind of Chinese medicine preparation for being used to treat gout - Google Patents

A kind of Chinese medicine preparation for being used to treat gout Download PDF

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Publication number
CN107261092A
CN107261092A CN201710537902.2A CN201710537902A CN107261092A CN 107261092 A CN107261092 A CN 107261092A CN 201710537902 A CN201710537902 A CN 201710537902A CN 107261092 A CN107261092 A CN 107261092A
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China
Prior art keywords
grams
root
chinese
bark
chinese medicine
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CN201710537902.2A
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Chinese (zh)
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金云龙
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Individual
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Individual
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/56—Materials from animals other than mammals
    • A61K35/58—Reptiles
    • A61K35/586—Turtles; Tortoises, e.g. terrapins
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    • A61K35/56—Materials from animals other than mammals
    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
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Abstract

A kind of to be used to treat the Chinese medicine preparation of gout, prescription is：Windproof 10 grams, 10 grams of the root bark of shaggy-fruited dittany, 10 grams of the root of Dahurain angelica, 10 grams of rattletop, 20 grams of Ligusticum wallichii, 15 grams of notopterygium root, 10 grams of tribulus terrestris, 20 grams of rhizoma Gastrodiae, 20 grams of the root of Chinese clematis, 20 grams of bark of ash, 10 grams of the root bark of Chinese wolf-berry, 10 grams of rhizoma zingiberis, 10 grams of calamus, 6 grams of Chinese cassia tree, 15 grams of levisticum, 10 grams of the tuber of multiflower knotweed, 30 grams of the fruit of Chinese wolfberry, 10 grams of monkshood, 20 grams of the root of fangji, 30 grams of Ramulus Taxilli, 30 grams of coix seed, 20 grams of erythrina bark, 5 grams of monkshood, 5 grams of radix aconiti agrestis, 15 grams of scorpio；This reasonable recipe, prepares simple, and Chinese medicine composition is pollution-free, no drug residue, have no drug resistance, and cost is low, and materials are wide, and bioavilability is high, curative effect highly significant.The present invention preferably goes out several Ten Herbs according to traditional Chinese medical science traditional theory, and them is constituted pure Chinese medicinal preparation according to optimum ratio, and the healthy of people has been effectively ensured.

Description

A kind of Chinese medicine preparation for being used to treat gout
Technical field
The present invention relates to technical field of Chinese medicine, and in particular to a kind of Chinese medicine preparation for being used to treat gout.
Background technology
Gout be it is a kind of be led to one group of disease of tissue damage because long-term disorders of purine metabolism, blood uric acid increase, it is also known as " high Uricacidemia ", belongs to arthritic one kind, also known as metabolic arthritis.Clinical manifestation：Involvement is shown as during gouty attack,acute The serious pain in joint, swelling, stiff, heating, and symptom occur unexpected.Arthralgia acute attack is the typical case of acute gout Symptom.Seizure of disease is more to be especially apt to occur in far-end of limb joint after slight damage, hyperalimentation or relevant disease, typical case Symptom send out in toes (podagra), also can cause renal colic because of urate calculi.Chronic gout is become with destructive joint to be turned to Feature.
Though the similar drug for the treatment of gout is more currently on the market, most analgesic effects are of short duration, and side effect is larger.
The content of the invention
The technical problems to be solved by the invention are to provide that a kind of formula is simple, cure rate it is high be used for treat gout Chinese medicine preparation.
The technical problems to be solved by the invention are realized using following technical scheme：
A kind of Chinese medicine preparation for being used to treat gout, component is as follows：
Prescription one：Windproof 10 grams, 10 grams of the root bark of shaggy-fruited dittany, 10 grams of the root of Dahurain angelica, 10 grams of rattletop, 20 grams of Ligusticum wallichii, 15 grams of notopterygium root, tribulus terrestris 10 grams, 20 grams of rhizoma Gastrodiae, 20 grams of the root of Chinese clematis, 20 grams of bark of ash, 10 grams of the root bark of Chinese wolf-berry, 10 grams of rhizoma zingiberis, 10 grams of calamus, 6 grams of Chinese cassia tree, levisticum 15 Gram, 10 grams of the tuber of multiflower knotweed, 30 grams of the fruit of Chinese wolfberry, 10 grams of monkshood, 20 grams of the root of fangji, 30 grams of Ramulus Taxilli, 30 grams of coix seed, 20 grams of erythrina bark, river 5 grams of crow, 5 grams of radix aconiti agrestis, 15 grams of scorpio；
Prescription two：10 grams of the bark of eucommia, 10 grams of, Bi Collettiis, 10 grams of Semen Cuscutae, 35 grams of sheep bone, 35 grams of Cowhells, 35 grams of deer's sinew, tortoiseshell 30 Gram, 20 grams of the red sage root, 15 grams of pseudo-ginseng, 20 grams of Radix Angelicae Sinensis, 20 grams of the dried rhizome of rehmannia, 10 grams of the root of herbaceous peony, 10 grams of frankincense, 10 grams of myrrh, 20 grams of the Radix Astragali, mountain 20 grams of medicine, 20 grams of the bighead atractylodes rhizome, 10 grams of ginseng, 10 grams of Poria cocos, 10 grams of Fructus Aurantii, 15 grams of aster, 15 grams of lycopodium calvatum, 10 grams of caulis trachelospermi, chicken 15 grams of blood rattan, 10 grams of earthworm；
Prescription three：6 grams of cassia twig, 10 grams of barrenwort, 6 grams of asarum, 10 grams of malt, 10 grams of Divine Comedy, 10 grams of hawthorn, the bark of official magnolia 10 Gram, 10 grams of nutmeg, 10 grams of the dried immature fruit of citron orange；
The acting as of prescription one strengthens muscles and bones, clearing damp；Prescription two act as promoting blood circulation, and tonifying Qi, relaxing muscles and tendons is active；Prescription three Act as Hui Yang, help digestion.
Usage：3 stages are divided into, the first stage takes one 10 doses of prescription, and second stage takes 2 10 doses of prescription, the 3rd Stage takes 3 10 doses of prescription, is within 30 days a course for the treatment of, daily 1 dose, decoct soup agent.It may be made as pill, capsule, tablet etc. various Dosage form.
Pharmaceutical preparation of the present invention has carried out substantial amounts of animal acute toxicity test, long-term toxicity test for animals and treatment disease A large amount of clinical tests of disease, the use link that treatment disease is put into the medicine provides science and objectively foundation.Its experiment side Method and result of the test difference are as follows：
(1) animal acute toxicity test is carried out to medicine prepared by the present invention：
Medicine：Bulk drug used in the present invention is commercially available from common Chinese shop, and its specification meets national Chinese medicine mark It is accurate.
Experimental animal：Small white mouse, body weight is bought in 50g or so, male and female random selection by market.
Method and result：Small white mouse 30 is taken, it is hungry 20 hours or so, 30ml is fed several times daily by every, continuously Feed one week, observe 10 days, mouse activity is normal, non-toxic reaction, no death.Show oral liquid without acute toxicity, clinical application Dosage safety.
(2) long-term toxicity test for animals is carried out to medicine prepared by the present invention：
Experimental animal：Big white mouse, body weight is bought in 120-130g, male and female random selection by market.
Method and result：Big white mouse 20 is taken, is divided into 2 groups, every group 10, wherein the 1st group as administration group, it is every by every It feeds 35ml several times, and the 2nd group of diet as a control group, once a day, is continuously fed 90 days, body weight is surveyed, in last 24 hours sacrificed by decapitation after single administration, survey blood, routine urinalysis, liver function, renal function, core, the internal organ, tissues observed form such as kidney Change, observe dosage effect, observation diet, activity change, experiment prove administration group compared with control group without significantly become Change, equal non-toxic reaction is a kind of safe drugs.
In order to verify clinical efficacy, this prescription is tried out in the first urgent disorder in orthopaedics hospital of Jie Shou institutes of traditional Chinese medicine and boundary respectively, by with Machine chooses wherein 100 gout patients, and the course for the treatment of is most short one month, most long for 1 year.
Recovery clinical improvement rate >=5%, effective clinical improvement rate >=72%, effective clinical improvement rate >=22%, invalid face Bed improvement rate >=1%, total effective rate 99%.
The beneficial effects of the invention are as follows：This reasonable recipe, prepares simple, Chinese medicine composition is pollution-free, no drug residue, without resistance Property, cost is low, and materials are wide, and bioavilability is high, curative effect highly significant.The present invention preferably goes out tens according to traditional Chinese medical science traditional theory Taste Chinese medicine, and them is constituted pure Chinese medicinal preparation according to optimum ratio, the healthy of people has been effectively ensured.
Embodiment
In order that the technical means, the inventive features, the objects and the advantages of the present invention are easy to understand, tie below Specific embodiment is closed, the present invention is expanded on further.
Embodiment 1
A kind of Chinese medicine preparation for being used to treat gout, component is as follows：
Prescription one：Windproof 10 grams, 10 grams of the root bark of shaggy-fruited dittany, 10 grams of the root of Dahurain angelica, 10 grams of rattletop, 20 grams of Ligusticum wallichii, 15 grams of notopterygium root, tribulus terrestris 10 grams, 20 grams of rhizoma Gastrodiae, 20 grams of the root of Chinese clematis, 20 grams of bark of ash, 10 grams of the root bark of Chinese wolf-berry, 10 grams of rhizoma zingiberis, 10 grams of calamus, 6 grams of Chinese cassia tree, levisticum 15 Gram, 10 grams of the tuber of multiflower knotweed, 30 grams of the fruit of Chinese wolfberry, 10 grams of monkshood, 20 grams of the root of fangji, 30 grams of Ramulus Taxilli, 30 grams of coix seed, 20 grams of erythrina bark, river 5 grams of crow, 5 grams of radix aconiti agrestis, 15 grams of scorpio；
Prescription two：10 grams of the bark of eucommia, 10 grams of, Bi Collettiis, 10 grams of Semen Cuscutae, 35 grams of sheep bone, 35 grams of Cowhells, 35 grams of deer's sinew, tortoiseshell 30 Gram, 20 grams of the red sage root, 15 grams of pseudo-ginseng, 20 grams of Radix Angelicae Sinensis, 20 grams of the dried rhizome of rehmannia, 10 grams of the root of herbaceous peony, 10 grams of frankincense, 10 grams of myrrh, 20 grams of the Radix Astragali, mountain 20 grams of medicine, 20 grams of the bighead atractylodes rhizome, 10 grams of ginseng, 10 grams of Poria cocos, 10 grams of Fructus Aurantii, 15 grams of aster, 15 grams of lycopodium calvatum, 10 grams of caulis trachelospermi, chicken 15 grams of blood rattan, 10 grams of earthworm；
Prescription three：6 grams of cassia twig, 10 grams of barrenwort, 6 grams of asarum, 10 grams of malt, 10 grams of Divine Comedy, 10 grams of hawthorn, the bark of official magnolia 10 Gram, 10 grams of nutmeg, 10 grams of the dried immature fruit of citron orange；
The acting as of prescription one strengthens muscles and bones, clearing damp；Prescription two act as promoting blood circulation, and tonifying Qi, relaxing muscles and tendons is active；Prescription three Act as Hui Yang, help digestion.
Usage：3 stages are divided into, the first stage takes one 10 doses of prescription, and second stage takes 2 10 doses of prescription, the 3rd Stage takes 3 10 doses of prescription, is within 30 days a course for the treatment of, daily 1 dose, decoct soup agent.
Model case：
Case 1：Zhang, man, 62 years old, Anhui Province Jieshou City brick market town, on March 20th, 2016 went to a doctor.Suffer from gout has for 4 years Remaining, control of taking medicine always, Chinese medicine Western medicine has, DeGrain.And arthralgia, arthroncus, inconvenient activity.Later I Place, gives the medicine of the embodiment of the present invention 1, does not ache at posterior joint January, and arthroncus disappears, and activity is freely.
Case 2：Shen so-and-so, man, 64 years old, Anhui Province Jieshou City Jin Zhai townshiies, August in 2016 was gone to a doctor on the 12nd.Patient's nothing before 1 year There is the stiff pain of multiple joints of whole body under obvious inducement, aggravated when pain is especially with overcast and rainy and night, oral anti-inflammation analgesic is matched somebody with somebody Close herbal fumigation, symptom alleviated, is discontinued after above-mentioned symptom exacerbation, the state of an illness is again and again over 1 year.Later here, gives this The medicine of inventive embodiments 1, does not ache January at posterior joint, and activity freely, is had a medical check-up and has no that other are special without obvious positive sign, main suit It is different uncomfortable, to consolidate curative effect, patient's one course for the treatment of of after treatment again after 2 months.
The general principle and principal character and advantages of the present invention of the present invention has been shown and described above.The technology of the industry Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the simply explanation described in above-described embodiment and specification is originally The principle of invention, without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, these changes Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its Equivalent thereof.

Claims (5)

1. a kind of Chinese medicine preparation for being used to treat gout, it is characterised in that component is as follows：
Prescription one：Windproof 10 grams, 10 grams of the root bark of shaggy-fruited dittany, 10 grams of the root of Dahurain angelica, 10 grams of rattletop, 20 grams of Ligusticum wallichii, 15 grams of notopterygium root, tribulus terrestris 10 Gram, 20 grams of rhizoma Gastrodiae, 20 grams of the root of Chinese clematis, 20 grams of bark of ash, 10 grams of the root bark of Chinese wolf-berry, 10 grams of rhizoma zingiberis, 10 grams of calamus, 6 grams of Chinese cassia tree, levisticum 15 Gram, 10 grams of the tuber of multiflower knotweed, 30 grams of the fruit of Chinese wolfberry, 10 grams of monkshood, 20 grams of the root of fangji, 30 grams of Ramulus Taxilli, 30 grams of coix seed, 20 grams of erythrina bark, river 5 grams of crow, 5 grams of radix aconiti agrestis, 15 grams of scorpio；
Prescription two：10 grams of the bark of eucommia, 10 grams of, Bi Collettiis, 10 grams of Semen Cuscutae, 35 grams of sheep bone, 35 grams of Cowhells, 35 grams of deer's sinew, 30 grams of tortoiseshell, 20 grams of the red sage root, 15 grams of pseudo-ginseng, 20 grams of Radix Angelicae Sinensis, 20 grams of the dried rhizome of rehmannia, 10 grams of the root of herbaceous peony, 10 grams of frankincense, 10 grams of myrrh, 20 grams of the Radix Astragali, Chinese yam 20 grams, 20 grams of the bighead atractylodes rhizome, 10 grams of ginseng, 10 grams of Poria cocos, 10 grams of Fructus Aurantii, 15 grams of aster, 15 grams of lycopodium calvatum, 10 grams of caulis trachelospermi, chicken blood 15 grams of rattan, 10 grams of earthworm；
Prescription three：6 grams of cassia twig, 10 grams of barrenwort, 6 grams of asarum, 10 grams of malt, 10 grams of Divine Comedy, 10 grams of hawthorn, 10 grams of the bark of official magnolia, meat Cool 10 grams, 10 grams of the dried immature fruit of citron orange.
2. a kind of Chinese medicine preparation for being used to treat gout according to claim 1, it is characterised in that the preparation is soup Agent.
3. a kind of Chinese medicine preparation for being used to treat gout according to claim 1, it is characterised in that the preparation is glue Capsule.
4. a kind of Chinese medicine preparation for being used to treat gout according to claim 1, it is characterised in that the preparation is ball Agent.
5. a kind of Chinese medicine preparation for being used to treat gout according to claim 1, it is characterised in that the preparation is piece Agent.
CN201710537902.2A 2017-07-04 2017-07-04 A kind of Chinese medicine preparation for being used to treat gout Withdrawn CN107261092A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108888724A (en) * 2018-09-26 2018-11-27 韩勇 One kind is for preventing antipodagric Chinese materia medica preparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108888724A (en) * 2018-09-26 2018-11-27 韩勇 One kind is for preventing antipodagric Chinese materia medica preparation

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Application publication date: 20171020