CN107260934A - It is a kind of to be used to treat capsule medicine of obesity and preparation method thereof - Google Patents

It is a kind of to be used to treat capsule medicine of obesity and preparation method thereof Download PDF

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Publication number
CN107260934A
CN107260934A CN201710577474.6A CN201710577474A CN107260934A CN 107260934 A CN107260934 A CN 107260934A CN 201710577474 A CN201710577474 A CN 201710577474A CN 107260934 A CN107260934 A CN 107260934A
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Prior art keywords
medicine
obesity
treat
chinese
barrenwort
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孙思远
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Sichuan Yichuang Biotechnology Co Ltd
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Sichuan Yichuang Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of capsule medicine for being used to treat obesity provided according to the traditional Chinese medical science the understanding mechanism of obesity, each component and its mass parts ratio of the medicine is as follows:90~350g of the Radix Astragali, 30~100g of pseudo-ginseng, 150~260g of Radix Codonopsis, 30~65g of Resina Draconis, 50~180g of the bighead atractylodes rhizome, 30~120g of hawthorn, 50~200g of the red sage root, rhizoma atractylodis(Fry)30~100g, 150~320g of French beans, 80~180g of golden cypress, 30~100g of the fruit of Chinese magnoliavine, 50~120g of barrenwort, 100~160g of Poria cocos;The medicine that the present invention is provided is a Chinese prescription treated both principal and secondary aspect of disease.

Description

It is a kind of to be used to treat capsule medicine of obesity and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of capsule medicine for being used to treat obesity, particularly The field of the capsule medicine used for obesity patient and preparation method thereof.
Background technology
Doctor thinks:Obesity is one group of common metabolism disease group.It is unnecessary when human body feed heat is more than consumption of calorie Heat is with storage as fat in internal, and its amount exceedes normal physiological requirement, and develops into obesity then during up to certain value.Just The 15%~18% of normal male adult adipose tissue mass percentage of liveweight, women accounts for 20%~25%.Increase with the age, body fat proportion Corresponding increase.On fat appraisal procedure, including anthropometry, dual energy X-ray absorptiometry, ultrasound, CT, infrared induction method Etc. a variety of.Such as claim simple obesity without obvious cause of disease person, there is clear and definite cause of disease person referred to as secondary obesity.
So, with regard to how to find it is a kind of can effectively treat the medicine of obesity, be an urgent problem needed to be solved.
The content of the invention
With continuing to develop for China's traditional Chinese medicine, in treatment obesity, people gradually appreciate Chinese traditional treatment The advantage of obesity, and the advantage such as good effect, instant effect, toxic side effect be small over the course for the treatment of, for existing western medical treatment fertilizer The present situation of fat disease, the purpose of the present invention is to be to provide a kind of capsule medicine for being used to treat obesity, to solve obesity The problem of patient gets well early.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and mass parts Than can effectively treat above-mentioned obesity.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is:There is provided a kind of for treating obesity Capsule medicine and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are than as follows:
90~350g of the Radix Astragali, 30~100g of pseudo-ginseng, 150~260g of Radix Codonopsis, 30~65g of Resina Draconis, 50~180g of the bighead atractylodes rhizome, hawthorn 30 ~120g, 50~200g of the red sage root, rhizoma atractylodis(Fry)30~100g, 150~320g of French beans, 80~180g of golden cypress, the fruit of Chinese magnoliavine 30~ 100g, 50~120g of barrenwort, 100~160g of Poria cocos.
It is a kind of be used for treat capsule medicine of obesity and preparation method thereof, it is characterised in that the medicine each Component and its mass parts are than as follows:
100~300g of the Radix Astragali, 35~90g of pseudo-ginseng, 170~230g of Radix Codonopsis, 35~55g of Resina Draconis, 60~150g of the bighead atractylodes rhizome, hawthorn 35 ~105g, 60~170g of the red sage root, rhizoma atractylodis(Fry)35~90g, 170~280g of French beans, 90~160g of golden cypress, 35~90g of the fruit of Chinese magnoliavine, 60~120g of barrenwort, 115~140g of Poria cocos.
It is a kind of to be used to treat capsule medicine of obesity and preparation method thereof, it is characterised in that " preferred plan " Medicine each component and its mass parts than as follows:
Radix Astragali 260g, pseudo-ginseng 80g, Radix Codonopsis 200g, Resina Draconis 50g, bighead atractylodes rhizome 130g, hawthorn 95g, red sage root 150g, rhizoma atractylodis(Fry) 80g, French beans 250g, golden cypress 140g, fruit of Chinese magnoliavine 80g, barrenwort 100g, Poria cocos 120g.
It is a kind of to be used to treat capsule medicine of obesity and preparation method thereof, it is characterised in that methods described is included such as Lower step is prepared from:
A, above-mentioned raw materials Chinese medicine is picked to impurity, dust and dried after, be ground into superfine end according to mass parts ratio stand-by;
B, the method for preparing Chinese medicine capsules according to tradition, after ground superfine myrrh thing sieving, are put into medicine device and mix Uniformly, then it is prepared into capsule(Total length after its capsule is sealed is 23.3mm, medicinal powder capacity 0.4~0.5g/), packing Sealing.
It is a kind of to be used to treat capsule medicine of obesity and preparation method thereof, it is characterised in that the instructions of taking is: By the capsule medicine prepared three times a day to take, once a dose in the morning, afternoon and evening, and dosage 2g (4)/time, warm water is sent Clothes.It is within 15 days a course for the treatment of, 3~7 courses for the treatment of of typically taking medicine, it is seen that positive effect.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component:
The Radix Astragali, nature and flavor:Sweet, temperature, the effect of with invigorating qi for strengthening superficies, inducing diuresis to remove edema, pus draining and toxin expelling, expelling pus and promoting granulation, myogenic, for controlling Treat treatment deficiency of vital energy weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult to burst, long Burst do not hold back, flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes, chronic rephrilis protinuria, diabetes;
Pseudo-ginseng, nature and flavor:Sweet, slight bitter, temperature, the effect of with dissipate stasis of blood hemostasis, detumescence ding-tong, for treat spitting of blood, haematemesis, bleeding from five sense organs or subcutaneous tissue, Have blood in stool, uterine bleeding, traumatism and bleeding, chest and abdomen are twinged, tumbling and swelling;
Radix Codonopsis, nature and flavor:It is sweet, mild-natured, the effect of with strengthening the spleen and tonifying the lung, nourishing generate fluid, for treating weakness of the spleen and the stomach, deficiency of food just Half congealed, limbs fatigue, the deficiency syndrome of the lung are breathed with cough, shortness of breath spontaneous perspiration, gas micro- two lose etc. disease;
Resina Draconis, nature and flavor:It is warm-natured, flat, sweet, salty, it is nontoxic, with invigorating circulation of blood to dissipate blood stasis and reducing swelling and relieving pain, softening and resolving hard mass, myogenic sore The effect of, have a pain for treating traumatic injury, hemostasis, traumatism and bleeding;
The bighead atractylodes rhizome, nature and flavor:It is bitter, sweet, warm-natured, with strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, it is antiabortive the effect of, for treating temper The few abdominal distension of weakness, spiritlessness and weakness, deficiency of food, thin big loose stool, fluid retention stagnating in the interior, difficult urination, oedema, phlegmatic vertigo, warm numbness are ached, gas Empty spontaneous perspiration, fetal irritability;
Hawthorn, nature and flavor:Sour sweet, tepor, it is nontoxic, with digestion gathered food, change the stagnant stasis of blood the effect of, for Therapeutic diet to be stagnant, gastral cavity abdomen is swollen Bitterly, dysentery, dysmenorrhea due to blood stasis, amenorrhoea, postpartum abdominal pain, lochiorrhagia;
The red sage root, nature and flavor:It is bitter, be slightly cold, the effect of with promoting blood circulation for regulating menstruation, stasis-dispelling and pain-killing, cool blood to disappear carbuncle, relieving restlessness that clears away heart-fire, nourishing blood and tranquilization, For treating irregular menstruation, closed dysmenorrhea, a lump in the abdomen causing distension and pain, chest and abdomen shouting pain, hot numbness pain, sore swell and ache curative, dysphoria and insomnia, liver and spleen swell Greatly, the disease such as angina pectoris;
Rhizoma atractylodis(Fry), nature and flavor:Acrid, bitter, warm, the effect of with drying damp and strengthening spleen, expelling wind and clearing away cold, improving eyesight, for treat abdominal fullness and distention, Diarrhea, oedema, arthralgia pain due to rheumatism, anemofrigid cold, yctalopia;
French beans, nature and flavor:It is sweet, flat, with nvigorating the spleen and in, relieve summer heat dampness elimination the effect of, for treat summer-heat and damp vomit and diarrhoea, it is insufficiency of the spleen vomit it is inverse, food It is few let out long, the disease such as water stops quenching one's thirst, leukorrhea with reddish discharge, infantile malnutrition;
Golden cypress, nature and flavor:It is bitter, cold, the effect of with heat-clearing and damp-drying drug, purging intense heat and detonicating, for treating damp-heat dysentery, diarrhea, jaundice, dream Something lost, stranguria with turbid discharge, band under, hectic fever due to yin labor heat and aphthae, red eye, swell pain, skin sore, skin eczema;
The fruit of Chinese magnoliavine, nature and flavor:Sour, sweet, temperature, with the effect of astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, kidney calming is restrained, for treating chronic diarrhea not Only, chronic cough and dyspnea of deficiency type, palpitaition, insomnia, dreaminess, spontaneous perspiration, night sweat, injury thirst, quench one's thirst, pass out semen, involuntary emission;
Barrenwort, nature and flavor:Xin Gan, temperature, the effect of with tonifying kidney and strengthening yang, dispelling wind and eliminating dampness, are not lifted, urine leaching for treating impotence The disease such as drip, muscles and bones contraction urgency, hemiplegia, waist-leg weakness, arthralgia pain due to rheumatism, four limbs are meciless;
Poria cocos, nature and flavor:It is sweet, light, flat, the effect of with sharp water medicine, diuretics with the action of eliminating dampness, for treat difficult urination, oedema turgor, Phlegm and retained fluid coughs inverse, vomiting, spleen eating less, diarrhea, palpitation and restlessness, insomnia forgetfulness, seminal emission gonorrhoea.
Medicine of the present invention is the principle based on Chinese traditional treatment obesity, is thought from pharmacological action and mechanism of action:It is just fat Each raw material herbal medicine efficacy in disease, medicine provided by the present invention is played altogether, has good therapeutic effect to above-mentioned disease.
Embodiment
A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned obesity, the medicine prepared using the formula Thing good drug efficacy, instant effect is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to the tool of the present invention Body embodiment is described in further detail:
Embodiment 1:
A kind of capsule medicine for being used to treat obesity, it is characterised in that each component and its mass parts ratio of the medicine It is as follows:
Radix Astragali 260g, pseudo-ginseng 80g, Radix Codonopsis 200g, Resina Draconis 50g, bighead atractylodes rhizome 130g, hawthorn 95g, red sage root 150g, rhizoma atractylodis(Fry) 80g, French beans 250g, golden cypress 140g, fruit of Chinese magnoliavine 80g, barrenwort 100g, Poria cocos 120g.
Embodiment 2:
A kind of capsule medicine for being used to treat obesity, it is characterised in that each component and its mass parts ratio of the medicine It is as follows:
Radix Astragali 300g, pseudo-ginseng 90g, Radix Codonopsis 230g, Resina Draconis 55g, bighead atractylodes rhizome 150g, hawthorn 105g, red sage root 170g, rhizoma atractylodis(Fry) 90g, French beans 280g, golden cypress 160g, fruit of Chinese magnoliavine 90g, barrenwort 120g, Poria cocos 140g.
Embodiment 3:
A kind of capsule medicine for being used to treat obesity, it is characterised in that each component and its mass parts ratio of the medicine It is as follows:
Radix Astragali 350g, pseudo-ginseng 100g, Radix Codonopsis 260g, Resina Draconis 65g, bighead atractylodes rhizome 180g, hawthorn 120g, red sage root 200g, rhizoma atractylodis(Fry) 100g, French beans 320g, golden cypress 180g, fruit of Chinese magnoliavine 100g, barrenwort 120g, Poria cocos 160g.
Model case
Through clinical conditions obesity patient totally 366, the age is 230 of more than 35 years old, only 136 for 35 years old with Under.Reach 220 of positive effect in 346 patients, effective 126, total effective rate is up to 100%.

Claims (3)

1. a kind of capsule medicine for being used to treat obesity, it is characterised in that each component and its mass parts of the medicine Than as follows:
90~350g of the Radix Astragali, 30~100g of pseudo-ginseng, 150~260g of Radix Codonopsis, 30~65g of Resina Draconis, 50~180g of the bighead atractylodes rhizome, hawthorn 30 ~120g, 50~200g of the red sage root, rhizoma atractylodis(Fry)30~100g, 150~320g of French beans, 80~180g of golden cypress, the fruit of Chinese magnoliavine 30~ 100g, 50~120g of barrenwort, 100~160g of Poria cocos.
2. according to claim 1 be used to treat the capsule medicine of obesity, it is characterised in that the medicine each Component and its mass parts are than as follows:
100~300g of the Radix Astragali, 35~90g of pseudo-ginseng, 170~230g of Radix Codonopsis, 35~55g of Resina Draconis, 60~150g of the bighead atractylodes rhizome, hawthorn 35 ~105g, 60~170g of the red sage root, rhizoma atractylodis(Fry)35~90g, 170~280g of French beans, 90~160g of golden cypress, 35~90g of the fruit of Chinese magnoliavine, 60~120g of barrenwort, 115~140g of Poria cocos.
3. being used for according to claim 1 to 2 treats the capsule medicine of obesity, it is characterised in that the medicine Each component and its mass parts are than as follows:
Radix Astragali 260g, pseudo-ginseng 80g, Radix Codonopsis 200g, Resina Draconis 50g, bighead atractylodes rhizome 130g, hawthorn 95g, red sage root 150g, rhizoma atractylodis(Fry) 80g, French beans 250g, golden cypress 140g, fruit of Chinese magnoliavine 80g, barrenwort 100g, Poria cocos 120g.
CN201710577474.6A 2017-07-15 2017-07-15 It is a kind of to be used to treat capsule medicine of obesity and preparation method thereof Withdrawn CN107260934A (en)

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Application publication date: 20171020