CN107224635A - A kind of injection of insulin is pumped monitoring device - Google Patents

A kind of injection of insulin is pumped monitoring device Download PDF

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Publication number
CN107224635A
CN107224635A CN201710528892.6A CN201710528892A CN107224635A CN 107224635 A CN107224635 A CN 107224635A CN 201710528892 A CN201710528892 A CN 201710528892A CN 107224635 A CN107224635 A CN 107224635A
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CN
China
Prior art keywords
layer
varistor layer
injection
varistor
substrate
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710528892.6A
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Chinese (zh)
Inventor
熊作平
张珽
井华
谷文
王冉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suzhou Neng Sida Electronic Science And Technology Co Ltd
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Suzhou Neng Sida Electronic Science And Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Suzhou Neng Sida Electronic Science And Technology Co Ltd filed Critical Suzhou Neng Sida Electronic Science And Technology Co Ltd
Priority to CN201710528892.6A priority Critical patent/CN107224635A/en
Publication of CN107224635A publication Critical patent/CN107224635A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804Flow controllers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3334Measuring or controlling the flow rate

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The present invention relates to a kind of pressure monitoring technology, specially a kind of injection of insulin pump pressure monitoring device, high sensitivity flexible film pressure sensor based on nano material is integrated on insulin infusion pump, the monitoring of pump pressure is perceived by nanometer flexible film pressure sensor to adjust control motor rotary speed and then control the injection speed of insulin syringe, simulation physiological insulin secretion is realized with reference to blood sugar for human body content, including device body, medicine storage, rubber piston, nanometer flexible film pressure sensor, micro motor, screw type push rod and control system, the medicine storage is located at the side of device body, rubber piston is located on medicine storage, the nanometer flexible film pressure sensor is located on rubber piston, the micro motor is located on device body, the power transmission shaft of the micro motor is connected by screw type push rod with rubber piston.

Description

A kind of injection of insulin is pumped monitoring device
Technical field
The present invention relates to a kind of pressure monitoring technology, specially a kind of injection of insulin pump pressure monitoring device.
Background technology
With the improvement of people ' s living standards with the transformation of life style, diabetes have become frequently-occurring disease and common disease. According to IDF (IDF) statistics, only in the children that the whole world is less than 15 years old, type 1 diabetes illness year increases Plus rate about 3%, and China human mortality radix is big, the absolute number of infant is still a huge population.Insulin pump is that blood glucose control is controlled The best means for the treatment of, presently commercially available has conventional motors formula insulin pump, the piezoelectric micropump based on piezoelectric ceramic piece etc., but tradition Insulin pump volume be unfavorable for greatly very much it is portable use, and only do not reached optimal with certain speed injection insulin Therapeutic effect;The stability of piezoelectric micropump based on piezoelectric ceramic piece is bad and there is decline, influence insulin dose injection essence Degree, delays therapeutic effect.
The content of the invention
It is an object of the present invention to provide a kind of injection of insulin pump pressure monitoring device, by the Gao Ling based on nano material Sensitivity flexible film pressure sensor is integrated on insulin infusion pump, by nanometer flexible film pressure sensor to pump pressure Monitoring perceives to adjust control motor rotary speed and then control the injection speed of insulin syringe, is realized with reference to blood sugar for human body content Simulate physiological insulin secretion.
Invention solves the technical scheme that is used of its technical problem:A kind of injection of insulin is pumped monitoring device, including Device body, medicine storage, rubber piston, nanometer flexible film pressure sensor, micro motor, screw type push rod and control system System, the medicine storage is located at the side of device body, and rubber piston is located on medicine storage, the nanometer flexible film pressure sensing Device is located on rubber piston, and the micro motor is located on device body, and the power transmission shaft of the micro motor is pushed away by screw type Bar is connected with rubber piston, in addition to blood sugar monitoring module, and the blood sugar monitoring module is electrically connected with control system, the nanometer Flexible film pressure sensor includes the first substrate, first electrode layer, the first varistor layer, supporting layer, the second electrode lay, the second pressure Photosensitive layer and the second substrate, first varistor layer are arranged on above first electrode layer, and second varistor layer is arranged on the second electricity Pole layer top, first varistor layer and the second varistor layer are connected by supporting layer, first varistor layer and the second varistor layer Between there is gap, the first electrode layer is set on the first substrate, and the second electrode lay is located on the second substrate.
Preferably, the supporting layer is ring-shaped support and is located between the first substrate and the second substrate, described first Varistor layer and the second varistor layer are located in supporting layer and the first varistor layer and the second varistor layer have gap.
Preferably, the supporting layer is bar and is located at the side of the first varistor layer and the second varistor layer.
Preferably, first varistor layer and the second varistor layer are with the spongy of three-dimensional poroid micro-structural.
Preferably, first varistor layer and the second varistor layer are made up of nano combined pressure sensitive,
The nano combined pressure sensitive includes conductive material, high polymer material, dispersion and auxiliary agent.
Preferably, 1 μm -500 μm of the thickness of first varistor layer and the second varistor layer.
Preferably, first substrate and the second substrate are made by fexible film.
The beneficial effect of invention is:In order to realize the intellectuality of insulin pump, safe ready diabetic uses, this hair It is bright that a kind of device that monitoring is pumped for injection of insulin is provided, the high sensitivity flexible film pressure based on nano material is passed Sensor is integrated on insulin infusion pump, and the monitoring of pump pressure is perceived by nanometer flexible film pressure sensor to adjust control Motor rotary speed and then the injection speed for controlling insulin syringe, simulation physiological insulin point is realized with reference to blood sugar for human body content Secrete.
The present invention injection of insulin pump pressure monitoring device according in control system by patient (generally in the guidance of doctor Under) oneself, according to the fluctuation situation of blood glucose, set the infusion dosage of individuation, in conjunction with needed within certain period infusion Insulin dose correspondence promotes the program of pressure value, and when insulin infusion pump starts injection, micro motor promotes screw type to push away Bar is close to rubber piston, and when push rod touches the nanometer flexible film pressure sensor on rubber piston, sensor is just Push rod pressure can be perceived and data feedback will be detected to control system, control system is according to setting instruction control micro motor Rotating speed and then micro and accurately promote rubber piston, insulin is accurately securely entered in vivo.
Brief description of the drawings
Fig. 1 is pumped the structural representation of monitoring device for the injection of insulin of the present invention.
Fig. 2 is pumped the diagrammatic cross-section of monitoring device for the injection of insulin of the present invention.
Brief description of the drawings:1st, device body, 2, medicine storage, 3, rubber piston, 4, nanometer flexible film pressure sensor, 41, First substrate, 42, first electrode layer, the 43, first varistor layer, 44, supporting layer, 45, the second electrode lay, the 46, second varistor layer, 47th, the second substrate, 5, micro motor, 6, screw type push rod, 7, control system, 8, blood sugar monitoring module.
Embodiment
Invention is described in further detail presently in connection with accompanying drawing.These accompanying drawings are simplified schematic diagram, only to show Meaning mode illustrates the basic structure of invention, therefore it only shows the composition relevant with invention.
As illustrated, a kind of injection of insulin pump pressure monitoring device, including device body 1, medicine storage 2, rubber piston 3, Nanometer flexible film pressure sensor 4, micro motor 5, screw type push rod 6 and control system 7, the medicine storage 2 are located at device The side of body 1, rubber piston 3 is located on medicine storage 2, and the nanometer flexible film pressure sensor 4 is located at rubber piston 3 On, the micro motor 5 is located on device body 1, and the power transmission shaft of the micro motor 5 is lived by screw type push rod 6 and rubber Plug 3 is connected, in addition to blood sugar monitoring module 8, and the blood sugar monitoring module 8 is electrically connected with control system 7, and the nanometer is soft thin Membrane pressure sensor 4 include the first substrate 41, first electrode layer 42, the first varistor layer 43, supporting layer 44, the second electrode lay 45, Second varistor layer 46 and the second substrate 47, first varistor layer 43 are arranged on the top of first electrode layer 42, and described second is pressure-sensitive Layer 46 is arranged on the top of the second electrode lay 45, and the varistor layer 46 of the first varistor layer 43 and second is connected by supporting layer 44, institute State and there is gap between the first varistor layer 43 and the second varistor layer 46, the first electrode layer 42 is set on first substrate 41, institute The second electrode lay 45 is stated to be located on the second substrate 47.
The supporting layer 44 is ring-shaped support and is located between the first substrate 41 and the second substrate 47 that described first is pressure-sensitive The varistor layer 46 of layer 43 and second is located in supporting layer 44 and the first varistor layer 43 and the second varistor layer 46 have gap.
The supporting layer 44 is bar and is located at the side of the first varistor layer 43 and the second varistor layer 46.
The varistor layer 46 of first varistor layer 43 and second is with the spongy of three-dimensional poroid micro-structural.
The varistor layer 46 of first varistor layer 43 and second is made up of nano combined pressure sensitive, described nano combined pressure-sensitive Material includes conductive material, high polymer material, dispersion and auxiliary agent.The thickness of the varistor layer 46 of first varistor layer 43 and second 1μm—500μm。
Injection of insulin according to claim 1 is pumped monitoring device, it is characterised in that:The He of first substrate 41 Second substrate 47 is made by fexible film.
The present invention injection of insulin pump pressure monitoring device according in control system by patient (generally in the guidance of doctor Under) oneself, according to the fluctuation situation of blood glucose, set the infusion dosage of individuation, in conjunction with needed within certain period infusion Insulin dose correspondence promotes the program of pressure value, and when insulin infusion pump starts injection, micro motor promotes screw type to push away Bar is close to rubber piston, and when push rod touches the nanometer flexible film pressure sensor on rubber piston, sensor is just Push rod pressure can be perceived and data feedback will be detected to control system, control system is according to setting instruction control micro motor Rotating speed and then micro and accurately promote rubber piston, insulin is accurately securely entered in vivo.
The nanometer flexible film pressure sensor of the present invention, mainly includes the first PET film substrate, first electrode layer, the One varistor layer, supporting layer, and the second PET film substrate, the second electrode lay, the second varistor layer.By first and second PET film lining The two sides containing varistor layer forms the flexible film pressure sensor of the present invention every empty assembling on bottom, when pressure-sensitive in flexible substrate When layer is pressurized, the resistivity of pressure sensitive, which produces change and the change of two varistor layer contacts area, to be caused resistance variations and realizes to pressure The perception of power, after external force is removed, the resistivity of pressure sensitive returns to original value again, and the application uses the resistance of pressure sensitive The synergy that rate changes and two varistor layer contacts area change further improves transducer sensitivity.First electrode layer is located at First PET film surface and with substrate be in close contact, the first varistor layer be located at first electrode layer surface and contacted with electrode seal, Supporting layer is located at the first pressure-sensitive layer surface;The second electrode lay is located at the second PET film substrate surface and is in close contact with substrate, the Two varistor layers are located at second electrode layer surface and contacted with electrode seal.
The nanometer flexible film pressure sensor of the present invention can also be a kind of following structures:Mainly include the first soft PI Substrate, first electrode layer, and the second soft PI substrates, the second varistor layer, supporting layer.Electricity will be contained on first soft PI substrates The face of pole layer forms the soft thin of the present invention by supporting layer with the face containing varistor layer on the second soft PI substrates every empty assembling Membrane pressure sensor.
Nanometer flexible film pressure sensor also includes the processing of circuit module in matching control system, nanometer pressure Force snesor gathers push rod pressure signal and is converted into corresponding electrical output signal, transmits a signal to processing of circuit module, electricity The electrical signal of reception is carried out the processing such as shaping, amplification, filtering, A/D conversions by the signal processing circuit in the processing module of road, then Output electric signal is converted into by the algorithm being integrated in processing of circuit module by digitized pressure value and feeds back to control system. Signal transmission form is wired electrical transmission or is wirelessly transferred connection.The monitoring infusion pressure of the nano pressure sensor real-time accurate Power so that insulin pump pressure energy is sensitively monitored, can effectively prevent that liquid-transport pipe-line from blocking or drug storage has been noted and alarm (report Police's formula can be that buzzing, vibration or LED color etc. are warned).
The injection of insulin is pumped monitoring device can " precognition " blood sugar level, imitation pancreatic secretion by blood sugar monitoring module The mechanism of insulin, reed time controll delivery system prevents injection is excessive from causing low blood to the speed of patient's internal injection insulin Sugar;The present invention using Intellisense, automatically control by the way of can reduce use cost, facilitate the treatment of diabetes patient, mitigate and pass through Ji and stress, level of improving the quality of living.
Using the above-mentioned desirable embodiment according to invention as enlightenment, by above-mentioned description, relevant staff is complete Can without departing from the scope of the technological thought of the present invention', carry out various changes and amendments, this invention it is technical Scope is not limited to the content on specification, it is necessary to its technical scope is determined according to right.

Claims (7)

1. a kind of injection of insulin is pumped monitoring device, it is characterised in that:Lived including device body (1), medicine storage (2), rubber Fill in (3), nanometer flexible film pressure sensor (4), micro motor (5), screw type push rod (6) and control system (7), the storage Medicine device (2) is located at the side of device body (1), and rubber piston (3) is located on medicine storage (2), the nanometer flexible film pressure Sensor (4) is located on rubber piston (3), and the micro motor (5) is located on device body (1), the micro motor (5) Power transmission shaft is connected by screw type push rod (6) with rubber piston (3), in addition to blood sugar monitoring module (8), the blood sugar monitoring mould Block (8) is electrically connected with control system (7), and the nanometer flexible film pressure sensor (4) includes the first substrate (41), the first electricity Pole layer (42), the first varistor layer (43), supporting layer (44), the second electrode lay (45), the second varistor layer (46) and the second substrate (47), first varistor layer (43) is arranged on above first electrode layer (42), and second varistor layer (46) is arranged on second Above electrode layer (45), first varistor layer (43) and the second varistor layer (46) are connected by supporting layer (44), and described first There is gap between varistor layer (43) and the second varistor layer (46), the first electrode layer (42) is located on the first substrate (41), The second electrode lay (45) is located on the second substrate (47).
2. injection of insulin according to claim 1 is pumped monitoring device, it is characterised in that:The supporting layer (44) is ring Shape supporter and positioned between the first substrate (41) and the second substrate (47), first varistor layer (43) and the second varistor layer (46) it is located in supporting layer (44) and the first varistor layer (43) and the second varistor layer (46) has gap.
3. injection of insulin according to claim 1 is pumped monitoring device, it is characterised in that:The supporting layer (44) is bar Shape thing and the side for being located at the first varistor layer (43) and the second varistor layer (46).
4. injection of insulin according to claim 1 is pumped monitoring device, it is characterised in that:First varistor layer (43) It is with the spongy of three-dimensional poroid micro-structural with the second varistor layer (46).
5. injection of insulin according to claim 1 is pumped monitoring device, it is characterised in that:First varistor layer (43) It is made up with the second varistor layer (46) of nano combined pressure sensitive, the nano combined pressure sensitive includes conductive material, high score Sub- material, dispersion and auxiliary agent.
6. injection of insulin according to claim 1 is pumped monitoring device, it is characterised in that:First varistor layer (43) With 1 μm -500 μm of the thickness of the second varistor layer (46).
7. injection of insulin according to claim 1 is pumped monitoring device, it is characterised in that:First substrate (41) and Second substrate (47) is made by fexible film.
CN201710528892.6A 2017-07-01 2017-07-01 A kind of injection of insulin is pumped monitoring device Pending CN107224635A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111939389A (en) * 2020-09-02 2020-11-17 张涛元 Anesthetic liquid continuous quantitative injection device
CN114366933A (en) * 2022-01-24 2022-04-19 中南大学湘雅二医院 Method and system for regulating micro pump based on voice control
CN118576819A (en) * 2024-06-18 2024-09-03 深圳恩多克医疗有限公司 Multistage lifting structure and infusion apparatus comprising same

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2728505Y (en) * 2004-09-17 2005-09-28 冯威健 Injection pump
US20090299290A1 (en) * 1998-10-29 2009-12-03 Medtronic Minimed, Inc. External Infusion Device with a Vented Housing
CN102151345A (en) * 2011-04-25 2011-08-17 无锡沃骐医疗科技有限公司 Injector
CN103007391A (en) * 2012-12-19 2013-04-03 四川大学 Predictive adaptive control method and system for liquid medicament push-injecting
CN202904527U (en) * 2012-10-24 2013-04-24 江苏畅微电子科技有限公司 Curved surface flexible pressure induction type electronic whiteboard
CN203417371U (en) * 2013-08-26 2014-02-05 苏州鼎诺医疗设备有限公司 Infusion pump
CN104257367A (en) * 2014-09-16 2015-01-07 苏州能斯达电子科技有限公司 Flexible pressure sensor with attaching function and preparation method thereof
CN205268740U (en) * 2015-12-02 2016-06-01 青岛市第三人民医院 Infusion pump
CN205698711U (en) * 2016-04-01 2016-11-23 国网安徽省电力公司培训中心 A kind of insulin pump with infusion warning function
CN205879411U (en) * 2016-07-01 2017-01-11 南昌欧菲光科技有限公司 Pressure drag sensor and pressure -sensitive element who is used for pressure drag sensor
CN106708305A (en) * 2015-11-13 2017-05-24 南昌欧菲光科技有限公司 Touch display apparatus
CN208229177U (en) * 2017-07-01 2018-12-14 苏州能斯达电子科技有限公司 A kind of injection of insulin pump pressure monitoring device

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090299290A1 (en) * 1998-10-29 2009-12-03 Medtronic Minimed, Inc. External Infusion Device with a Vented Housing
CN2728505Y (en) * 2004-09-17 2005-09-28 冯威健 Injection pump
CN102151345A (en) * 2011-04-25 2011-08-17 无锡沃骐医疗科技有限公司 Injector
CN202904527U (en) * 2012-10-24 2013-04-24 江苏畅微电子科技有限公司 Curved surface flexible pressure induction type electronic whiteboard
CN103007391A (en) * 2012-12-19 2013-04-03 四川大学 Predictive adaptive control method and system for liquid medicament push-injecting
CN203417371U (en) * 2013-08-26 2014-02-05 苏州鼎诺医疗设备有限公司 Infusion pump
CN104257367A (en) * 2014-09-16 2015-01-07 苏州能斯达电子科技有限公司 Flexible pressure sensor with attaching function and preparation method thereof
CN106708305A (en) * 2015-11-13 2017-05-24 南昌欧菲光科技有限公司 Touch display apparatus
CN205268740U (en) * 2015-12-02 2016-06-01 青岛市第三人民医院 Infusion pump
CN205698711U (en) * 2016-04-01 2016-11-23 国网安徽省电力公司培训中心 A kind of insulin pump with infusion warning function
CN205879411U (en) * 2016-07-01 2017-01-11 南昌欧菲光科技有限公司 Pressure drag sensor and pressure -sensitive element who is used for pressure drag sensor
CN208229177U (en) * 2017-07-01 2018-12-14 苏州能斯达电子科技有限公司 A kind of injection of insulin pump pressure monitoring device

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111939389A (en) * 2020-09-02 2020-11-17 张涛元 Anesthetic liquid continuous quantitative injection device
CN114366933A (en) * 2022-01-24 2022-04-19 中南大学湘雅二医院 Method and system for regulating micro pump based on voice control
CN114366933B (en) * 2022-01-24 2022-08-02 中南大学湘雅二医院 Method and system for regulating micro pump based on voice control
CN118576819A (en) * 2024-06-18 2024-09-03 深圳恩多克医疗有限公司 Multistage lifting structure and infusion apparatus comprising same

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Inventor after: Xiong Zuoping

Inventor after: Jing Hua

Inventor after: Gu Wen

Inventor before: Xiong Zuoping

Inventor before: Zhang Ting

Inventor before: Jing Hua

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Inventor before: Wang Ran

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Application publication date: 20171003

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