CN107223064B - 用于穿透生物屏障的微穿透器设备 - Google Patents

用于穿透生物屏障的微穿透器设备 Download PDF

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Publication number
CN107223064B
CN107223064B CN201580074402.9A CN201580074402A CN107223064B CN 107223064 B CN107223064 B CN 107223064B CN 201580074402 A CN201580074402 A CN 201580074402A CN 107223064 B CN107223064 B CN 107223064B
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CN
China
Prior art keywords
protrusion
micropenetrator
arm
head
flexible substrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201580074402.9A
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English (en)
Chinese (zh)
Other versions
CN107223064A (zh
Inventor
安德鲁·詹姆斯·柯比
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xobaderm Ltd
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Xobaderm Ltd
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Filing date
Publication date
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Publication of CN107223064A publication Critical patent/CN107223064A/zh
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Publication of CN107223064B publication Critical patent/CN107223064B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061—Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
CN201580074402.9A 2014-11-25 2015-11-25 用于穿透生物屏障的微穿透器设备 Expired - Fee Related CN107223064B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1420946.4 2014-11-25
GBGB1420946.4A GB201420946D0 (en) 2014-11-25 2014-11-25 Flexible device incorporating microperforators
GB1517832.0 2015-10-08
GB1517832.0A GB2533839B (en) 2014-11-25 2015-10-08 Micropenetrator device for penetrating a biological barrier
PCT/GB2015/053592 WO2016083803A2 (en) 2014-11-25 2015-11-25 Micropenetrator device for penetrating a biological barrier

Publications (2)

Publication Number Publication Date
CN107223064A CN107223064A (zh) 2017-09-29
CN107223064B true CN107223064B (zh) 2021-04-30

Family

ID=52292516

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580074402.9A Expired - Fee Related CN107223064B (zh) 2014-11-25 2015-11-25 用于穿透生物屏障的微穿透器设备

Country Status (11)

Country Link
US (2) US10532200B2 (enExample)
EP (1) EP3223899B1 (enExample)
JP (1) JP6900316B2 (enExample)
KR (1) KR20170094253A (enExample)
CN (1) CN107223064B (enExample)
AU (1) AU2015352176B2 (enExample)
BR (1) BR112017010935B1 (enExample)
GB (2) GB201420946D0 (enExample)
RU (1) RU2017122163A (enExample)
WO (1) WO2016083803A2 (enExample)
ZA (1) ZA201704235B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017006958A1 (ja) * 2015-07-07 2017-01-12 凸版印刷株式会社 経皮投与デバイス
GB201716391D0 (en) * 2017-10-06 2017-11-22 Xobaderm Ltd Kit for delivery of an active compound into a biological barrier
CN111437207A (zh) * 2020-05-08 2020-07-24 广州市泫享生物科技有限公司 一种具有渗透功能的敷贴式美容贴及其制备方法
FR3129584B1 (fr) * 2021-11-30 2024-06-28 Pkvitality Procédé de fabrication d’un module élémentaire d’un capteur à microaiguilles

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4966159A (en) * 1981-12-14 1990-10-30 Maganias Nicholas H Allergy test strip
WO2014126317A1 (ko) * 2013-02-14 2014-08-21 (주)라온 마이크로니들치료기

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1200140A1 (en) * 1999-08-03 2002-05-02 Smith & Nephew, Inc. Controlled release implantable devices
WO2001041863A1 (en) * 1999-12-10 2001-06-14 Alza Corporation Device and method for enhancing microprotrusion skin piercing
US7828827B2 (en) * 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
AU2005243727B2 (en) * 2004-04-12 2011-04-28 Allergan, Inc. Multi-site injection system
US20070270738A1 (en) * 2005-04-25 2007-11-22 Wu Jeffrey M Method of treating ACNE with stratum corneum piercing patch
US20070078414A1 (en) * 2005-08-05 2007-04-05 Mcallister Devin V Methods and devices for delivering agents across biological barriers
US20070293816A1 (en) * 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
US7785301B2 (en) 2006-11-28 2010-08-31 Vadim V Yuzhakov Tissue conforming microneedle array and patch for transdermal drug delivery or biological fluid collection
KR101033514B1 (ko) * 2009-06-02 2011-05-09 (주)마이티시스템 유연한 미세바늘 패치 시스템 및 그 제작방법
PT2563450T (pt) * 2010-04-28 2017-08-28 Kimberly Clark Co Dispositivo para entrega de medicação para a artrite reumatóide
US8900616B2 (en) * 2010-10-22 2014-12-02 Covidien Lp System and method for satellite drug delivery
DE102012014653A1 (de) * 2012-07-24 2014-01-30 Edelgard Liebl Vorrichtung zur Behandlung der Haut
JP2014097163A (ja) * 2012-11-14 2014-05-29 Ikeda Kikai Sangyo Kk マイクロニードルアレイの製造方法
CN103203072B (zh) * 2013-03-25 2015-05-20 清华大学 金属微针阵列柔性贴片、经皮给药器件及经皮给药贴片

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4966159A (en) * 1981-12-14 1990-10-30 Maganias Nicholas H Allergy test strip
WO2014126317A1 (ko) * 2013-02-14 2014-08-21 (주)라온 마이크로니들치료기

Also Published As

Publication number Publication date
EP3223899A2 (en) 2017-10-04
CN107223064A (zh) 2017-09-29
JP6900316B2 (ja) 2021-07-07
RU2017122163A3 (enExample) 2019-06-06
US10532200B2 (en) 2020-01-14
BR112017010935B1 (pt) 2022-03-08
US20170319839A1 (en) 2017-11-09
AU2015352176A1 (en) 2017-07-13
EP3223899B1 (en) 2021-07-07
US20200230389A1 (en) 2020-07-23
GB2533839A (en) 2016-07-06
AU2015352176B2 (en) 2020-08-06
JP2017538567A (ja) 2017-12-28
GB201420946D0 (en) 2015-01-07
GB201517832D0 (en) 2015-11-25
RU2017122163A (ru) 2018-12-26
ZA201704235B (en) 2020-11-25
KR20170094253A (ko) 2017-08-17
WO2016083803A3 (en) 2016-07-21
WO2016083803A2 (en) 2016-06-02
BR112017010935A2 (pt) 2018-02-14
GB2533839B (en) 2020-09-16

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Granted publication date: 20210430