CN107213276A - A kind of pharmaceutical composition for treating rheumatoid arthritis - Google Patents
A kind of pharmaceutical composition for treating rheumatoid arthritis Download PDFInfo
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- CN107213276A CN107213276A CN201710339259.2A CN201710339259A CN107213276A CN 107213276 A CN107213276 A CN 107213276A CN 201710339259 A CN201710339259 A CN 201710339259A CN 107213276 A CN107213276 A CN 107213276A
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- rheumatoid arthritis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/486—Millettia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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Abstract
The invention provides a kind of pharmaceutical composition for treating rheumatoid arthritis, it is made up of the raw material components of following several weights：5 20 parts of 10 30 parts of reticulate millettia, 10 35 parts of centella, 15 35 parts of the Radix Astragali, 10 25 parts of duckweed, 15 40 parts of chrysanthemum and prepared rhizome of rehmannia.The present invention is by the way that above several drugses component is used as medicine, using the synergy between medicine, improves curative effect, produces the action effect for the treatment of rheumatoid arthritis.Traditional Chinese medicinal components of the present invention are relatively common in daily life, easily gather and cost is low, and the preparation being made also has simple treatment, safety and stability and beneficial effect evident in efficacy.
Description
Technical field
The invention mainly relates to orthopedic drug therapy field, more particularly, to a kind of rheumatoid arthritis for the treatment of
Pharmaceutical composition.
Background technology
Rheumatoid arthritis is a kind of unknown systemic disease chronic, based on inflammatory synovitis of cause of disease.Its feature
It is hand, the multi-joint of sufficient Minor articulus, symmetry, aggressive arthritis, is often accompanied by organ outside joint and is involved serum class wind
Wet factor positive, can cause joint deformity and function to be lost.The incidence of disease of women is 2~3 times of male in morbidity crowd, can
Any age is betided, Gao Fa Nian Ling is 40~60 years old.
Patient with rheumatoid arthritis can typically produce the symptom of joint involvement, be mainly shown as：1. multi-joint
Involvement：In symmetry panarthritis.There are hand, foot, wrist, ankle and temporomandibular joint etc. in the joint being easily involved, other can also have elbow, shoulder,
Cervical vertebra, hip, knee joint etc..2. joint deformity：The deformity of hand has fusiformis swelling, ulnar side deflection, swan neck deformity, button style
Deformity etc..The deformity of foot, which has, faces upward microdactyly, valgus deformity, articulationes metatarsophalangeae subluxation, bending caused by the downward subluxation of caput metatarsale
In hammer toe and talipes valgus.3. other：There can be median nerve/Wan Guan ∕ tarsal tunnel syndromes, knee caused by posterior tibial nerve compression
Arthroedema squeezes into Xing Cheng popliteal cysts on rear side of joint, cervical vertebra involvement（2nd, 3 cervical vertebras are common）, can there is cervical pain, neck
Powerless and be difficult to keep its normal position, atlanto-axial subluxation should mutually have compression of spinal cord and VBI
Performance.In addition, can also be with body diseases such as weight loss, low-heat, tired sense, Cardiac Involvemant, respiratory system involvement, anaemias
Shape.
Treatment rheumatoid arthritis medicine mainly have nonsteroidal anti-inflammatory agent, slowly effect antirheumatic drug, immunodepressant,
Immune and biological agent and autonomic drug, though these medicines alleviate the symptom of rheumatoid arthritis to a certain extent, production
Raw side reaction is more, and often index is not effected a permanent cure.
The content of the invention
To solve above-mentioned the deficiencies in the prior art, the invention provides one kind treat simply, safety and stability, curative effect
The pharmaceutical composition of significant treatment gout.
To realize the purpose of the present invention, it is achieved using following technical scheme：
A kind of pharmaceutical composition for treating rheumatoid arthritis, is made up of the raw material components of following several weights：Chicken
5-20 parts of 10-30 parts of blood rattan, 10-35 parts of centella, 15-35 parts of the Radix Astragali, 10-25 parts of duckweed, 15-40 parts of chrysanthemum and prepared rhizome of rehmannia.
As preferred technical scheme, it is made up of the raw material components of following several weights：15-25 parts of reticulate millettia,
10-15 parts of 15-30 parts of centella, 20-30 parts of the Radix Astragali, 15-20 parts of duckweed, 20-35 parts of chrysanthemum and prepared rhizome of rehmannia.
As preferred technical scheme, it is made up of the raw material components of following several weights：20 parts of reticulate millettia, accumulated snow
13 parts of 20 parts of grass, 25 parts of the Radix Astragali, 18 parts of duckweed, 30 parts of chrysanthemum and prepared rhizome of rehmannia.
Main Chinese herbal medicine is according to traditional medicine and modern medical analysis in the present invention, and the property of medicine and pharmacological action are as follows：
Reticulate millettia：Hardship, Gan Wen.The thoughts of returning home, spleen, Liver Channel.With replenishing and activating blood, invigorating the spleen warm kidney, dispelling wind and removing obstruction in the meridians, the work(strengthened muscles and bones
Effect.
Centella：Hardship, Xin Han.Return liver, spleen, kidney channel.The effect of with activating blood circulation and reducing swelling, clearing heat and detoxicating, clearing damp and promoting diuresis.
The Radix Astragali：Nature and flavor are sweet, tepor；It is included into lung, the spleen channel；Exterior deficiency spontaneous perspiration is cured mainly, splenasthenic diarrhea, prolapse of the anus, the sinking of qi of middle-jiao disappears
Yearningly, ulcer such as does not close up the disease long.
Duckweed：Property and flavor of peppery and cold；It is included into lung, bladder warp；The effect of with promoting eruption, profit water detumescence is delivered, cure mainly：Flu hair
Burn, macula is impermeable, skin swelling, difficult urination.
Chrysanthemum：Pungent, sweet, hardship, is slightly cold.Return lung, Liver Channel.With dispelling wind and heat from the body, clear liver and improve vision, it is pancake liver-yang, clearing heat and detoxicating
The effect of.
Prepared rhizome of rehmannia：Nature and flavor：Sweet tepor.Channel tropism：Enter liver, stomach.Function：Nourishing yin and nourishing blood, warm filling liver kidney.Cure mainly：Kidney yin is not
Foot, soreness of waist leg is weak, and one's ears rang and spots danced before one's eyes, deficiency of liver-blood, woman uterine bleeding, irregular menstruation, cough due to yin deficiency, the disease such as quench one's thirst.
Compared with prior art, the positive effect of the present invention is：
（1）The present invention is by the way that above several drugses component is used as medicine, using the synergy between medicine, improves curative effect, and generation is controlled
Treat the action effect of rheumatoid arthritis.
（2）Traditional Chinese medicinal components of the present invention are relatively common in daily life, easily gather and cost is low, be made
Preparation also has simple treatment, safety and stability and beneficial effect evident in efficacy.
Embodiment
The present invention is described in further details with reference to embodiment.
Embodiment 1
Gather and weigh each raw material components of following several weights：20 parts of reticulate millettia, 20 parts of centella, 25 parts of the Radix Astragali,
13 parts of 18 parts of duckweed, 30 parts of chrysanthemum and prepared rhizome of rehmannia.
Decoction, every dose of 30ml are brewed into using conventional method.Instructions about how to take medicine and usage：Each taking one, take daily in morning and evening
With 2 times.
Embodiment 2
Gather and weigh each raw material components of following several weights：10 parts of reticulate millettia, 10 parts of centella, 15 parts of the Radix Astragali,
5 parts of 10 parts of duckweed, 15 parts of chrysanthemum and prepared rhizome of rehmannia.
Preparation method and instructions of taking be the same as Example 1.
Embodiment 3
Gather and weigh each raw material components of following several weights：30 parts of reticulate millettia, 35 parts of centella, 35 parts of the Radix Astragali,
20 parts of 25 parts of duckweed, 40 parts of chrysanthemum and prepared rhizome of rehmannia.
Preparation method and instructions of taking be the same as Example 1.
The clinical experiment report of embodiment 4：
Selection crowd：Selection clinically suffers from 150 cases of symptoms of rheumatoid arthritis, and diagnostic criteria is with reference to " U.S.'s class
The standard that rheumatism association " formulates, i.e., according to medical history, physical diagnosis and radiological examination result：The pain of the knee joint, is provided simultaneously with
3 in 6 conditions determine clinical diagnosis below, and 1. radiology shows spur and formed；2. it is stiff from morning to be less than 30 points
Clock；3. there is bone sound during joint motion；4. knee joint bone increases；5. there is bone tenderness；6. heated up without obvious synovial membrane.
Treatment method：Obtained decoction in embodiment 1 is taken to above-mentioned 150 cases daily, point morning and evening is twice, one every time,
Warm water delivery service, one month is a course for the treatment of.The state of an illness takes the 1-2 course for the treatment of compared with the lighter, and the state of an illness takes the 2-3 course for the treatment of compared with severe one.
Efficacy determination：1. fully recover：Gonalgia symptom disappears, and the morning stiffness time shortens or without morning stiffness, and physico-chemical examination is normal.
1. take a turn for the better：Gonalgia symptom mitigation, physico-chemical examination makes moderate progress.It is invalid：Gonalgia is without mitigation, and physico-chemical examination is without changing
Become.
Treatment results：In 150 cases for receiving this treatment, there are 25 recoveries from illness, 117 sb.'s illness took a favorable turn, 8 invalid.
Total effective rate is up to 94.67%.
Embodiment 5
As different from Example 4, what 150 patients of the present embodiment took is obtained decoction in embodiment 2 to the present embodiment.
Its treatment results is as follows：
In 150 cases for receiving this treatment, there are 24 recoveries from illness, 115 sb.'s illness took a favorable turn, 11 invalid.Total effective rate reaches
92.67%。
Embodiment 6
As different from Example 4, what 150 patients of the present embodiment took is obtained pill in embodiment 3 to the present embodiment.
Its treatment results is as follows：
In 150 cases for receiving this treatment, there are 23 recoveries from illness, 117 sb.'s illness took a favorable turn, 10 invalid.Total effective rate reaches
93.33%。
From the foregoing, the pharmaceutical composition of the present invention has significant curative effect for treatment rheumatoid arthritis, always have
Efficiency high is up to 90%.
Claims (3)
1. a kind of pharmaceutical composition for treating rheumatoid arthritis, it is characterised in that by the original of following several weights
Expect component composition：10-30 parts of reticulate millettia, 10-35 parts of centella, 15-35 parts of the Radix Astragali, 10-25 parts of duckweed, 15-40 parts of chrysanthemum and
5-20 parts of prepared rhizome of rehmannia.
2. a kind of pharmaceutical composition for treating rheumatoid arthritis according to claim 1, it is characterised in that by following
The raw material components composition of several weights：15-25 parts of reticulate millettia, 15-30 parts of centella, 20-30 parts of the Radix Astragali, duckweed 15-
10-15 parts of 20 parts, 20-35 parts of chrysanthemum and prepared rhizome of rehmannia.
3. a kind of pharmaceutical composition for treating rheumatoid arthritis according to claim 1, it is characterised in that by following
The raw material components composition of several weights：20 parts of reticulate millettia, 20 parts of centella, 25 parts of the Radix Astragali, 18 parts of duckweed, 30 parts of chrysanthemum
With 13 parts of prepared rhizome of rehmannia.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710339259.2A CN107213276A (en) | 2017-05-15 | 2017-05-15 | A kind of pharmaceutical composition for treating rheumatoid arthritis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710339259.2A CN107213276A (en) | 2017-05-15 | 2017-05-15 | A kind of pharmaceutical composition for treating rheumatoid arthritis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107213276A true CN107213276A (en) | 2017-09-29 |
Family
ID=59945075
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710339259.2A Withdrawn CN107213276A (en) | 2017-05-15 | 2017-05-15 | A kind of pharmaceutical composition for treating rheumatoid arthritis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107213276A (en) |
-
2017
- 2017-05-15 CN CN201710339259.2A patent/CN107213276A/en not_active Withdrawn
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20170929 |
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| WW01 | Invention patent application withdrawn after publication |