CN107169285A - A kind of course of disease information mobile collection system complete in real time and acquisition method - Google Patents
A kind of course of disease information mobile collection system complete in real time and acquisition method Download PDFInfo
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- CN107169285A CN107169285A CN201710343925.XA CN201710343925A CN107169285A CN 107169285 A CN107169285 A CN 107169285A CN 201710343925 A CN201710343925 A CN 201710343925A CN 107169285 A CN107169285 A CN 107169285A
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Abstract
The present invention provides a kind of course of disease information mobile collection system complete in real time and acquisition method, the data and hospital clinical case information data that accurate diagnostic data, intelligent wearable device are obtained are acquired and system combination, to the data of user from the genetic test data of molecular level, the clinical case data characterized to disease, to the sign Monitoring Data of routine health, carry out comprehensively collection and confluence analysis, overcome available data due to it is inaccurate caused by single dimensional analysis the shortcomings of, with good application value.
Description
Technical field
The present invention relates to a kind of information acquisition system, and in particular to a kind of course of disease information mobile collection system complete in real time and adopts
Diversity method.Data and hospital clinical case information that the system can obtain gene physical examination data, intelligent wearable device
Data are acquired and system combination.
Background technology
23andme external at present, the company such as domestic 360 ° of genes, 3Dmed, cloud health is all carrying out gene physical examination,
Detection project includes hereditary disease detection, drug metabolism detection, idiosyncrasy detection, tumor disease detection etc., but is due to accurate
Medical market is in the starting stage, and each company is only that preliminary analysis is carried out to genetic test result, not with client day
Normal sign Index and clinical information are integrated, and cause result to float on surface, and many people take the genetic test expense of costliness
With but not playing expected effect to life and prevention from suffering from the diseases in the future, cause the significant wastage of resource.
In addition, as intelligent wearable device on the market is more and more, most welcome with Intelligent bracelet by consumers in general,
By monitoring every sign Index of people, including blood pressure, heart rate, motion conditions, respiratory rate etc., user is facilitated to be known from time
Body health status, meanwhile, Intelligent bracelet is matched and data transfer by modes such as bluetooths with mobile phone terminal, interior of mobile phone
Software can carry out recording and monitoring in real time to data, but all data are only to rest on statistics level, due to not with
Other data are combined, and cause analysis result too simple, it is impossible to form effective daily guidance to user.
The data and hospital clinical case that accurate diagnostic data, intelligent wearable device are obtained of the invention
Information data is acquired and system combination, to the data of user from data --- the genetic test of molecular level, to disease table
Levy data --- clinical case, to routine health data --- sign is monitored, and multiple dimensions are acquired and integral data, to use
The analysis that family is presented is from inside to outside, from molecular nature to external presentation, from genetic analysis to apparent effect, and not only result is more accurate
Really, effective routine health can be more formed to user to instruct.Instant invention overcomes available data because single dimensional analysis is led
Cause it is inaccurate the shortcomings of, with good application value.
The content of the invention
It is an object of the invention to provide a kind of real time clinical course of disease information mobile collection system, the system includes genosome
Examine data acquisition module, intelligent wearable device and mobile phone terminal, hospital clinical case information data acquisition module, network application
Server and message processing module, gene physical examination data acquisition module, intelligent wearable device and mobile phone terminal, hospital clinical disease
The data of example information data acquisition module collection upload to network application server, message processing module and network by internet
Application server is connected and the information on network application server is collected and handled.
Further, system also includes output module.Output module is connected with message processing module, display information processing module
Result.
It is preferred that, message processing module is connected with mobile phone terminal, and result is showed into user.
Further, gene physical examination data collecting module collected drug metabolism detection data, idiosyncrasy detection data, disease
Detect data.
Examining report of the data from genetic test company, preferably 360 ° genes, 3Dmed, cloud health, rich inspections difficult to understand
The examining report that Yan Deng genetic tests company provides.
Drug metabolism detection data include but is not limited to antitumor class drug data, resisting mental disease class drug test number
According to function of immune system class drug data, antipyretic-antalgic anti-inflammatory drug data, medicine for digestive system data, circulatory system medicine
Thing data, metabolism and internal system drug data, antimicrobial class drug data, detoxify class drug data, nervous system medicine
Thing data, medicine for respiratory system data, hematological system drugs data, anaesthetic data.
The medicine includes but is not limited to adriamycin, DTX, Docetaxel, fluorouracil, endoxan, Ji Xita
Shore, methopterin, Kapo Platinum, thiopurine methyltransferase vigor, thiopurine methyltransferase activity, cis-platinum, TAM,
Taxol；SSRI classes antidepressants, Risperidone, Olanzapine, Paxil, Citalopram, lithium salts, amitriptyline, desipramine,
Nortriptyline, escitalopram；Abacavir, tacrolimus, Mycophenolate Mofetil；Diphosphonate, Risedronate, Qu Gelie
Ketone, insulin sensitizer, sulfonylurea drugs；Flucloxacillin, sulfonylurea drugs；PAI；Ah Si
Woods；Melbine, statins, warfarin, Carvedilol, bucindolol, bisulfate clopidogrel, Verapamil, blood vessel
Angiotensin Converting enzyme inhibitor, acenocoumarol, atenolol, Atorvastatin, metoprolol, statins；Naltrexone,
Abstinyl；Carbamazepine, phenytoinum naticum, Olanzapine；Montelukast, bronchodilator；Heroin-dependent；Diphosphonate, profit
Fill in phosphonate, troglitazone, insulin sensitizer, sulfonylurea drugs；Flucloxacillin, sulfonylurea drugs.
Idiosyncrasy detection data include but is not limited to risk of obesity data, perception data, work and study ability number
According to health index data, body parameter data, locomitivity data, exercise guide data, live speciality data, appearance sign
Data, nutritious food data.
Disease detection data include but is not limited to tumour data, endocrine system disease data, disease in the urological system data,
Disease of digestive system data, the nervous system disease data, respiratory disease data, orthopaedic disease data, disease of immune system
Data, skin disease data, diseases of the five sense organs data, circulation system disease data, virile diesae data, women's diseases data.
The disease includes but is not limited to：Lung cancer, breast cancer, stomach cancer, the cancer of the esophagus, colorectal cancer, carcinoma of urinary bladder, cancer of pancreas,
Thyroid cancer, kidney, nasopharyngeal carcinoma, liver cancer, carcinoma of mouth, laryngocarcinoma, chronic lymphocytic leukemia, melanoma, basal-cell carcinoma,
Glioma, meningioma, neuroblastoma, squamous cell carcinoma, follicular lymphoma, myeloproliferative tumour, abdominal aorta
Knurl, cerebral aneurysm, Hodgkin lymphoma；Type 1 diabetes, diabetes B, obesity, hypothyroidism；Chronic renal
Disease, Secondary cases nephrotic syndrome, idiopathic membranous nephropathy, kidney stone；Ulcerative enteritis, chylous diarrhea, gall stone, Crohn disease,
Alcoholic fatty liver, non-alcoholic fatty liver disease；Ulcerative enteritis, chylous diarrhea, gall stone, Crohn disease, alcoholic fatty liver,
Non-alcoholic fatty liver disease；Senile dementia, Parkinson, depression, restless leg syndrome, bipolar disorder, property on progressive core
Paralysis, schizophrenia, inclined head disease, cluster headache, ALS, alcohol dependence, barrier being moved attention deficit more
Hinder, obsessive compulsive disorder, Gilles de la Tourette's syndrome, nicotine dependence, essential tremor, narcolepsy；Asthma, chronic resistance
Plug property lung disease, pulmonary fibrosis；Osteoporosis, ankylosing spondylitis, scoliosis, scleromalacia, osteoarthritis, Waist disc
Herniation；Systemic loupus erythematosus, rheumatoid arthritis, gout, Behcet's disease, rheumatic arthritis, selectivity IgA lack
Fall into, Sjogren syndrome, PBC, multiple sclerosis are true, sarcoidosis；Niu Pi Xian, hereditary allergic dermatitis,
Leucoderma, cheloid, Dupuytren contracture disease, skin-type chorionitis；Exfoliation glaucoma, otospongiosis, allergic rhinitis, old age
Property ARM, alopecia areata；Auricular fibrillation, coronary heart disease, headstroke, VTE, peripheral arterial lesion, sudden cardiac death,
Hypertension, high fat of blood；Prostate cancer, male sterility, carcinoma of testis；It is cervical carcinoma, oophoroma, carcinoma of endometrium, fibroid, many
Capsule Ovary Syndrome, mullerianosis, intrahepatic cholestasis of pregnancy, gestational diabetes mellitus.
Further, intelligent wearable device is connected with mobile phone terminal by wireless connection technology.Intelligent wearable device is obtained
The electric signal arrived converts analog signals into data after analog-to-digital conversion, and data are dealt into mobile phone by wireless connection technology
Terminal.
Wireless connection technology includes NFC technique, bluetooth, GPRS, Zigbee-technology or wifi technologies.
Intelligent wearable device includes Intelligent bracelet and intelligent shoe etc., and motion conditions and health status to user make note
Record and assessment.
The motion that intelligent wearable device measures user by built-in sensor remember step, blood pressure, blood glucose, heart rate, body temperature,
The data such as pulse, sleep, respiratory rate, blood oxygen saturation, fat, mood, sweat.
The sensor includes following one or more：3-axis acceleration sensor, optics heart rate sensor, precision temperature
Sensor, biology sensor, blood glucose sensor, blood pressure sensor, body fat sensor etc..
Optics heart rate sensor detects heart rate using photoelectricity transmissometry.
Precision temperature sensor is using medical temperature-sensitive resistance detection body temperature.
Metabolin and electrolyte in biology sensor monitoring sweat, with reference to temperature data, differentiate whether user occurs tired
Labor or the situation of dehydration.
Blood glucose sensor contains specific enzyme, by detecting that skin body fluid measures blood sugar level.
Cuff pressure minor variations monitoring blood pressure caused by blood pressure sensor detection human body artery vascular wall vibrations.
Body fat sensor is using biologic resistance measurement user fat and muscle quality, body fat rate.
HRV (HIV), heart rate decelerations power (DC), continuous heart rate decelerations power are resulted in by continuous rhythm of the heart
(DRs), the correlation values such as heart rate day-night change trend (spoon type, non-spoon type, anti-spoon type).These numerical value have with cardiovascular and cerebrovascular disease
Very the correlation of high level, can be combined with the heart and brain related data in gene physical examination and clinical case, be cardiovascular related diseases
Risk assessment and diagnosis provide foundation.
Blood pressure sensor can be continued to monitor to human blood-pressure.Continuing to monitor for blood pressure helps to early diagnose high blood
Pressure, for take blood-pressure drug user monitor depressor it is whether long-acting, furthermore it is possible to reduce cerebral apoplexy, coronary heart disease and the heart
The incidence of dirty property sudden death.
Further, clinical case information data acquisition module collection patient essential information, clinical test information.
Patient's essential information include the age, household heredity factors, marriage situation, medical history, smoking, situations such as drink.
Clinical examination includes user's electronic health record and image data data.
Electronic health record and image data data be with the stored in file format such as DCM, ECG, JPG, PDF and upload to network should
Use server.
It is preferred that, cardiovascular and cerebrovascular disease monitoring in, collection by gene medical center cerebrovascular relevant disease gene data,
Blood pressure in routine health, rhythm of the heart data and clinical case cardiac ultrasound, electrocardiogram, heart function etc. check data, pass through
Internet uploads to network application server, and message processing module is collected and confluence analysis to uploading information, so as to use
Family provides an analysis result from inherent hereditary information (gene information) to external presentation (vital sign), and not only result is more
Plus convincingness is accurately had more, effective routine health more can be targetedly formed to user and is instructed or medication guide.
Gene physical examination data, intelligent wearable device Monitoring Data and hospital clinical disease of the message processing module to collection
Example information data information is sorted out according to classification of diseases.
The classification of diseases first order：Internal medicine, surgery, gynemetrics, oncology.
The classification of diseases second level：
Internal medicine mainly includes：Internal Medicine-Cardiovascular Dept., Neurology, Infectious Disease, division of endocrinology, hematology, immune internal medicine；Surgery
Mainly include：Neurosurgery, cardiovascular surgery, Urology Surgery, department of general surgery, thoracic surgery, anorectal surgical；Gynemetrics mainly wraps
Include：Gynaecology, obstetrics, reproductive endocrine, family planning section；Oncology mainly includes tumor in respiratory system, digestive system tumor, secreted
Urinary system tumour, blood circulation system tumour, kinematic system tumour, genital system and other tumours.
The classification of diseases third level：
Internal Medicine-Cardiovascular Dept. mainly includes atrial fibrillation, coronary heart disease, arrhythmia cordis, congenital heart disease, heart failure, angina pectoris etc.；Nerve
Internal medicine mainly includes palsy, dementia, depression, headache, motor neuron disease etc.；Infectious Disease mainly includes hepatitis B, the Middle East and breathes comprehensive
Simulator sickness, dengue fever, AIDS etc.；Division of endocrinology mainly includes diabetes, hyperthyroidism, obesity etc.；Hematology mainly includes white blood
Disease, hemophilia, anaemia etc.；Immune internal medicine mainly includes rheumatoid arthritis, gout, Behcet's disease, Sjogren syndrome etc..
Neurosurgery mainly includes cerebrovascular disease, Parkinson, trigeminal neuralgia, encephalopathic etc.；Cardiovascular surgery is mainly wrapped
Include cerebral infarction, heart infarction, heart disease, phlebothrombosis etc.；Urology Surgery mainly includes kidney stone, cystitis, prostatitis, nephrosis and integrated
Levy；Department of general surgery mainly includes pain, first aid, burn and scald, skin disease, injury gained in sports, fracture, thyroid nodule etc.；Thoracic surgery
Mainly include pulmonary emphysema, benign tumor of lung, bronchiectasis etc.；It is red that anorectal surgical mainly includes hemorrhoid, polyp of colon, crissum
Swollen, anal fistula etc..
Gynaecology mainly includes menstrual disorder, dysmenorrhoea, vaginitis, pelvic infecton, cervicitis etc.；Obstetrics mainly include gestation merging
Disease, tire are stopped, miscarried, postpartum haemorrhage, amniotic fluid embolism etc.；Reproductive endocrine mainly includes infertile, artificial insemination, test tube baby
Youngster, endometriosis, tubal occlusion, polycystic ovary syndrome etc.；Family planning section mainly includes contraception, the stream of people, drawn
Production etc..
Tumor in respiratory system mainly includes lung cancer, nasopharyngeal carcinoma, laryngocarcinoma；Digestive system tumor mainly includes stomach cancer, liver cancer, food
Pipe cancer, colorectal cancer, cancer of pancreas, gallbladder cancer, cardia cancer；Patients with Urinary System Tumors mainly includes kidney, carcinoma of urinary bladder, prostate cancer；
Blood circulation system tumour mainly includes leukaemia, lymph cancer, hemangioma；Kinematic system tumour mainly include osteocarcinoma, osteosarcoma,
Huppert's disease；Genital system mainly includes cervical carcinoma, mammary gland fibroma, uterine cancer, oophoroma, prostate cancer；Its
He mainly includes fatty cancer, breast cancer, brain tumor, squamous carcinoma, cutaneum carcinoma, thyroid cancer etc. at tumour.
Further, to gene physical examination data, routine health data and hospital under the classification of diseases module of each subdivision
Clinical case information data carries out various dimensions aggregation process.
Described aggregation process combines molecular basis of the pathogenesis, Clinical signs and daily sign system deep pair comprehensively
User's cause of disease is analyzed.
A kind of application method of real time clinical course of disease information mobile collection system：
1. by gene physical examination data collecting module collected gene physical examination data, upload to network application server；
2. intelligent wearable device collects routine health data, data are dealt into by mobile phone end by wireless connection technology
End, uploads to network application server；
3. by hospital clinical case information data collecting module collected patient essential information, clinical test information, upload
To network application server；
4. message processing module collects to the data for uploading to network application server, by data according to classification of diseases
Sorted out；
5. output module is connected with message processing module, the result of display information processing module.
It is preferred that, output module is mobile phone terminal, and result is exposed directly into user.
Brief description of the drawings
Fig. 1 is real time clinical course of disease information mobile collection system schematic
Fig. 2 is real time clinical course of disease information mobile collection system diagram
Fig. 3 is real time clinical course of disease information mobile collection system optimization figure
Fig. 4 is real time clinical course of disease information mobile collection system detail drawing
Embodiment
With reference to specific embodiment, the present invention is expanded on further, is only used for explaining the present invention, and it is not intended that to this
The limitation of invention.It will be understood by those skilled in the art that：Can in the case where not departing from the principle and objective of the present invention
So that these embodiments are carried out with a variety of change, modification, replacement and modification, the scope of the present invention is limited by claim and its equivalent
It is fixed.The experimental method of unreceipted actual conditions in the following example, generally according to normal condition or according to the bar proposed by manufacturer
Part examinations.
Embodiment 1
A kind of real time clinical course of disease information mobile collection system, the system includes gene physical examination data acquisition module, intelligence
Wearable device and mobile phone terminal, hospital clinical case information data acquisition module, network application server and information processing mould
Block, gene physical examination data acquisition module, intelligent wearable device and mobile phone terminal, hospital clinical case information data acquisition module
The data of collection upload to network application server by internet, and information is collected and located by message processing module
Reason.
Embodiment 2
A kind of real time clinical course of disease information mobile collection system, the system includes gene physical examination data acquisition module, intelligence
Wearable device and mobile phone terminal, hospital clinical case information data acquisition module, network application server, message processing module
And output module, gene physical examination data acquisition module, intelligent wearable device and mobile phone terminal, hospital clinical case information data
The data of acquisition module collection upload to network application server by internet, and information is converged by message processing module
Always with processing, output module is connected with message processing module, the result of display information processing module.
Embodiment 3
A kind of real time clinical course of disease information mobile collection system, the system includes gene physical examination data acquisition module, intelligence
Wearable device and mobile phone terminal, hospital clinical case information data acquisition module, network application server and information processing mould
Block, gene physical examination data acquisition module, intelligent wearable device and mobile phone terminal, hospital clinical case information data acquisition module
The data of collection upload to network application server by internet, and information is collected and located by message processing module
Reason, message processing module connection mobile phone terminal, user is showed by mobile phone terminal by result.
Embodiment 4
In cardiovascular and cerebrovascular disease monitoring, various dimensions gathered data：
Cardiovascular and cerebrovascular relevant disease gene data is extracted from gene physical examination data acquisition module, mainly includes circulatory system disease
Ospc gene detection data (such as auricular fibrillation, coronary heart disease, headstroke, VTE, peripheral arterial lesion, sudden cardiac death,
Hypertension, high fat of blood etc.)；Circulatory system drug metabolism detection data (are such as tieed up to melbine, statins, warfarin, card
Ground Lip river, bucindolol, bisulfate clopidogrel, Verapamil, angiotensin converting enzyme inhibitors, acenocoumarol, Ah replacing
Luo Er, Atorvastatin, metoprolol, statins side effect etc.).
The data such as blood pressure, blood glucose, heart rate, the blood oxygen saturation of monitoring are extracted from intelligent wearable device.
Clinical case cardiac ultrasound, electrocardiogram, heart function etc. are extracted from hospital's clinical case information data acquisition module
Check data.
Network application server is uploaded to by internet, message processing module collects to uploading information, then entered
Row classification, according to classification of diseases：
Internal medicine → Internal Medicine-Cardiovascular Dept. → atrial fibrillation, coronary heart disease, arrhythmia cordis, congenital heart disease, heart failure, angina pectoris；
Surgery → cardiovascular surgery → cerebral infarction, heart infarction, heart disease, phlebothrombosis；
Finally, user is presented to by mobile phone terminal, user can conveniently consult on mobile phone and be gathered below every kind of disease
Related data, show the analysis result from inherent hereditary information (gene information) to external presentation (vital sign), not only
As a result convincingness is more accurately had more, it is more targeted that effective routine health guidance or medication is formed to user and its doctor
Refer to.
Claims (10)
1. a kind of real time clinical course of disease information mobile collection system, the system includes gene physical examination data acquisition module, intelligence can
Wearable device and mobile phone terminal, hospital clinical case information data acquisition module, network application server and message processing module,
Characterized in that, gene physical examination data acquisition module, intelligent wearable device and mobile phone terminal, hospital clinical case information data
The data of acquisition module collection upload to network application server by internet, and message processing module is to network application server
On information collected and handled.
2. real time clinical course of disease information mobile collection system according to claim 1, it is characterised in that system also includes defeated
Go out module, output module is connected with message processing module, the result of display information processing.
3. real time clinical course of disease information mobile collection system according to claim 1, it is characterised in that message processing module
It is connected with mobile phone terminal, result is showed into user.
4. real time clinical course of disease information mobile collection system according to claim 1, it is characterised in that gene physical examination data
Acquisition module collection drug metabolism detection data, idiosyncrasy detection data, disease detection data.
5. real time clinical course of disease information mobile collection system according to claim 4, it is characterised in that drug metabolism is detected
Data include but is not limited to antitumor class drug data, resisting mental disease class drug test data, function of immune system class medicine
Data, antipyretic-antalgic anti-inflammatory drug data, medicine for digestive system data, circulatory system drug data, metabolism and endocrine system
System drug data, antimicrobial class drug data, detoxify class drug data, drugs for nervous data, medicine for respiratory system number
According to hematological system drugs data, anaesthetic data；Idiosyncrasy detection data include but is not limited to risk of obesity data, feel
Know capacity data, work and study capacity data, health index data, body parameter data, locomitivity data, exercise guide number
According to live speciality data, appearance sign data, nutritious food data；Disease detection data include but is not limited to tumour data, interior
Excretory system disease data, disease in the urological system data, disease of digestive system data, the nervous system disease data, respiratory system
Disease data, orthopaedic disease data, disease of immune system data, skin disease data, diseases of the five sense organs data, circulation system disease
Data, virile diesae data, women's diseases data.
6. real time clinical course of disease information mobile collection system according to claim 1, it is characterised in that intelligence is wearable to be set
It is standby to be connected with mobile phone terminal by wireless connection technology, it is preferred that wireless connection technology including NFC technique, bluetooth, GPRS,
Zigbee-technology and wifi technologies.
7. real time clinical course of disease information mobile collection system according to claim 1, it is characterised in that intelligence is wearable to be set
The standby motion that user is measured by built-in sensor remember step, blood pressure, blood glucose, heart rate, body temperature, pulse, sleep, respiratory rate,
Blood oxygen saturation, fat, mood, sweat data, it is preferred that sensor includes following one or more：3-axis acceleration is sensed
Device, optics heart rate sensor, precision temperature sensor, biology sensor, blood glucose sensor, blood pressure sensor, body fat sensor.
8. real time clinical course of disease information mobile collection system according to claim 1, it is characterised in that message processing module
Gene physical examination data, intelligent wearable device Monitoring Data and hospital clinical case information data message to collection are according to disease
Disease classification is sorted out, to gene physical examination data, routine health data and hospital under the classification of diseases module of each subdivision
Clinical case information data carries out various dimensions aggregation process.
9. a kind of application method of real time clinical course of disease information mobile collection system：
(1) by gene physical examination data collecting module collected gene physical examination data, network application server is uploaded to；
(2) intelligent wearable device collects routine health data, and data are dealt into mobile phone terminal by wireless connection technology, on
Pass to network application server；
(3) by hospital clinical case information data collecting module collected patient essential information, clinical test information, net is uploaded to
Network application server；
(4) message processing module collects to the data for uploading to network application server, and data are entered according to classification of diseases
Row is sorted out；
(5) output module is connected with message processing module, the result of display information processing module.
10. method according to claim 9, it is characterised in that output module is mobile phone terminal.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111431919A (en) * | 2020-03-31 | 2020-07-17 | 河北省科学院应用数学研究所 | Method for determining DRGs packets and DRGs packet system |
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| CN103961069A (en) * | 2014-05-07 | 2014-08-06 | 东南大学 | Intelligent health monitoring system based on cloud services |
| CN106650256A (en) * | 2016-12-20 | 2017-05-10 | 安徽安龙基因医学检验所有限公司 | Precise medical platform for molecular diagnosis and treatment |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040133358A1 (en) * | 1999-02-26 | 2004-07-08 | Bryant Stephen Paul | Clinical and diagnostic database and related methods |
| CN103961069A (en) * | 2014-05-07 | 2014-08-06 | 东南大学 | Intelligent health monitoring system based on cloud services |
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