CN107106125A - System and method for measuring arterial parameters - Google Patents
System and method for measuring arterial parameters Download PDFInfo
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- CN107106125A CN107106125A CN201580070187.5A CN201580070187A CN107106125A CN 107106125 A CN107106125 A CN 107106125A CN 201580070187 A CN201580070187 A CN 201580070187A CN 107106125 A CN107106125 A CN 107106125A
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- 238000000034 method Methods 0.000 title claims abstract description 34
- 210000001367 artery Anatomy 0.000 claims abstract description 73
- 230000036772 blood pressure Effects 0.000 claims abstract description 26
- 238000012545 processing Methods 0.000 claims abstract description 13
- 238000001361 intraarterial administration Methods 0.000 claims abstract description 10
- 230000017531 blood circulation Effects 0.000 claims abstract description 8
- 238000001514 detection method Methods 0.000 claims abstract description 6
- 230000008859 change Effects 0.000 claims description 16
- 238000005259 measurement Methods 0.000 claims description 13
- 238000002604 ultrasonography Methods 0.000 claims description 5
- 230000004872 arterial blood pressure Effects 0.000 claims description 2
- 238000004148 unit process Methods 0.000 claims description 2
- 238000004590 computer program Methods 0.000 claims 2
- 238000011437 continuous method Methods 0.000 claims 1
- 230000009897 systematic effect Effects 0.000 abstract 1
- 230000008569 process Effects 0.000 description 5
- 210000003462 vein Anatomy 0.000 description 5
- 238000002592 echocardiography Methods 0.000 description 4
- 239000000523 sample Substances 0.000 description 4
- 238000009530 blood pressure measurement Methods 0.000 description 3
- 230000035488 systolic blood pressure Effects 0.000 description 3
- 208000024172 Cardiovascular disease Diseases 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000035487 diastolic blood pressure Effects 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000001052 transient effect Effects 0.000 description 2
- 239000013598 vector Substances 0.000 description 2
- 238000007476 Maximum Likelihood Methods 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000010349 pulsation Effects 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
- A61B8/0891—Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
- A61B8/5223—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for extracting a diagnostic or physiological parameter from medical diagnostic data
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/06—Measuring blood flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/42—Details of probe positioning or probe attachment to the patient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/42—Details of probe positioning or probe attachment to the patient
- A61B8/4245—Details of probe positioning or probe attachment to the patient involving determining the position of the probe, e.g. with respect to an external reference frame or to the patient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/48—Diagnostic techniques
- A61B8/485—Diagnostic techniques involving measuring strain or elastic properties
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
Abstract
The present invention relates to a kind of system for measuring arterial parameters.The system of the present invention includes signal element, and it is used to provide radio frequency (RF) ultrasonic signal and demodulation RF ultrasonic signals and the relative data from thus obtained signal；For the detection unit for the presence for detecting the blood flow in artery；Recognition unit for recognizing the artery；For handling the data and for the processing unit for the expansion waveform for providing the artery；With at least one estimation unit estimated in multiple local intra-arterial parameters to the artery.It is used for the method for the systematic survey arterial parameters by the present invention the invention further relates to a kind of.Present invention has the advantage that by non-imaged, it is noninvasive and without band in the way of continuously measure other local intra-arterial parameters of localised blood pressure and such as peak systolic flow velocity, pulse wave number and arterial compliance measured value etc.
Description
Technical field
The present invention relates to measurement arterial parameters, relate more specifically to a kind of for measuring arterial parameters using rf ultrasound
System and method.
Background technology
Generally, blood pressure measurement is considered to be the ideal biological mark of the health status to gauge patient.Therefore, outside
Before section's operation or during general health is checked and even when patient is under medical observation, blood pressure is surveyed
Amount.By convention, blood pressure is measured on arteria brachialis to determine to shrink measured value and diastole measured value.These measured values generally by regarding
To be the standard for all arteries.
Generally, blood pressure is measured using sphygmomanometer.It is aortic blood pressure in this blood pressure measured, passes through the aortic blood
Pressure, in the case where there are some variation, estimates the blood pressure on arteria brachialis.This method mainly utilizes band, the band
Placed around upper arm and be inflated to be expanded into and overcharge contractive pressure, then, in release as the pressure produced by the inflation of band
During power, record systolic pressure and diastolic pressure.Here, it is important that, using size is properly determined to be suitable for the band of patient, with
Just reduce or eliminate the deviation in blood pressure measurement.
On the other hand, also blood pressure can be measured using ultrasound.This blood pressure measuring method based on ultrasound is usually using bright
Degree pattern (B-mode) is imaged and image processing algorithm follows the trail of the motion of artery.
Evidence shows that the blood pressure measured on arteria brachialis does not describe the actual blood pressure on other peripheral arterials.In spy
Determine acquisition absolute blood pressure on artery and have become imperative for assessing the imbalance related to blood vessel with handling.Therefore,
Localised blood pressure measurement together with the flow estimation in artery significantly improves the ability of diagnosis and monitoring cardiovascular disease.
In two above methods, not yet realize that localised blood pressure is measured.In addition, such as peak systolic flow velocity
(PSV), the measurement of a variety of other arterial parameters of pulse wave velocity (PWV), arterial stiffness or the like can not pass through
Available known devices or technology are realized.
US2014143064Al is disclosed to be used as parameter to calculate blood pressure by VPV.
Certainly, there are needs to measure localised blood pressure and other arterial parameters by single measurement process.Purport of the present invention
A kind of solution for the above needs is being provided.
The purpose of invention
It is an object of the invention to provide a kind of system for measuring local arterial parameters；
It is a kind of for including many of localised blood pressure by the measurement of single measurement process another object of the present invention is to provide
The system of individual local intra-arterial parameter；
A further object of the present invention is to provide a kind of method for being used to measure localised blood pressure by the system of the present invention；
And
It is used for it is still another object of the present invention to provide a kind of by the system of the present invention is measured by single measurement process
The method of a number of other arterial parameters.
The content of the invention
There is provided a kind of system for being used to measure arterial parameters using ultrasound in one aspect of the invention.The system
Including：Signal element, it is used to provide radio frequency (RF) ultrasonic signal and demodulation RF ultrasonic signals and from the letter thus obtained
Number relative data；Detection unit, it is used to detect the presence of blood flow in artery；Recognition unit, it is used to recognize institute
State artery；Processing unit, it is used to handle the data and the expansion waveform for providing the artery；And estimation unit,
It is used in the local intra-arterial parameter to the artery at least one estimate.
Advantageously, localised blood pressure and other arterial parameters are measured by single measurement process, thus cause diagnosis and
Monitor the improvement of the ability of cardiovascular disease.
The present invention provides a kind of by for measuring the solution that the non-imaged and noninvasive system and method for arterial parameters are realized
Certainly scheme.In addition, the invention provides a kind of solution that arterial parameters are measured in the way of without band.Furthermore, the present invention
Eliminate in order to determine blood pressure and to PSV absolute demand.
In a preferred embodiment of the invention, multiple element of transducers are arranged into grid configuration, to be moved from described
Multiple positions of arteries and veins obtain part RF ultrasonic signals simultaneously.
In a preferred embodiment of the invention, RF ultrasonic signals are used for determining to expand waveform, and it is captured because of blood
Pulsation caused by the change of artery diameter, the change of pressure waveform, the change of localised blood pressure and other from this
The change of fluctuating parameter.
In a preferred embodiment of the invention, demodulation RF ultrasonic signals be used to recognize artery of interest, and
For determining peak systolic flow velocity, which depict the presence of abnormal flow in the artery.
It is used for the method using ultrasonic measurement arterial parameters there is provided a kind of in another aspect of the present invention.The present invention
Method include：Radio frequency (RF) ultrasonic signal and demodulation RF ultrasonic signals are provided by signal element and from thus obtaining
The relative data of signal；The presence of blood flow in artery is detected by detection unit；Recognized by identifying device described dynamic
Arteries and veins；By data described in processing unit processes and provide the expansion waveform of the artery；And by estimation unit to described dynamic
At least one in the local intra-arterial parameter of arteries and veins is estimated.
In a preferred embodiment of the invention, method of the invention is implemented by the system of the present invention.
Brief description of the drawings
Referring to accompanying drawing, wherein：
Fig. 1 shows the system for measuring arterial parameters according to the present invention；
Fig. 2, which is shown from artery of interest, obtains rf data；
Fig. 3 depicts the echo pattern obtained at the different parts of artery of interest；With
Fig. 4 shows that sample expands waveform.
Embodiment
Below with reference to Fig. 1 to Fig. 4 further describes the present invention by non exhaustive exemplary embodiment.
In fig. 1 it is shown that a kind of system (100) for being used to measure arterial parameters.The system (100) includes signal element
(101), its multiple element of transducer with grid configuration arrangement.These element of transducers are individually or collectively operated
To provide the untreated radio frequency ultrasonic signal for the artery of interest for being suitable for pending measurement.According to the measurement bag of the present invention
Include the radio frequency ultrasonic signal utilized into untreated form and demodulation form.The radio demodulating unit (102) demodulation is untreated
Radio frequency ultrasonic signal.Probe unit (103) is set, to utilize the Doppler's frequency obtained from the radio frequency ultrasonic signal of demodulation
Modal data detects presence of the blood flow in artery of interest.In the presence of blood flow is detected, just pass through recognition unit (104)
Artery of interest is specifically recognized.Feedback signal is provided, continuously to obtain number for a few data cycle
According to so as to be further processed.The recognition unit has the one or more patterns relevant with each corresponding artery.
The data that processing unit (105) shows artery of interest with processing are provided, and it is then right in this manual
It is illustrated.
The signal obtained from element of transducer is influenceed by noise and transient behaviour.The untreated radio-frequency echo wave is believed
Number pre-processed to improve signal to noise ratio (SNR), and removed by using the matched filter for having bandpass filter below
Transient phenomena.Apply nonlinear gain and reflected with suppressing the high-amplitude from skin gel interface.
As shown in Figure 2, with regard to artery of interest, signal frame is obtained in specific time interval.It is placed on the table of body
Ultrasonic pulse is sent in body by the transducer (201) on face, so as to reach moving such as arteria carotis through soft tissue (202)
Arteries and veins (203).Ultrasonic pulse (204) from transducer be shown as reach artery (203) wall farther out and the pulse
Reflected.The ultrasonic pulse reflected is shown as (205).Obviously, ultrasonic pulse is transmitted, and these ultrasonic pulses are from straight
Footpath is reflected for the nearly wall and remote wall of D artery.These echoes are received by same transducer.Show echo in the time
It is spaced the data frame (Fl, F2 and F3) comprising amplitude information A (a, u) formed in T (ms).
Artery of interest at such identification is drawn into RF data, and waveform is specifically expanded for calculating artery.
Fig. 3 is shown in ultrasonic wave from the outer membrane (301) of artery (300) such as of interest, middle level (302) and inner membrance
Etc (303) different anatomic position reflected after echo pattern (1,2,3,4).From the internal layer (303) (inner membrance) of wall
Transition to the chamber (tube chamber) (304) positioned at intra-arterial side produces different echoes, and it is bright at both nearly wall and remote wall place
Aobvious.Stronger echo represents outermost layer (outer membrane) (301).Intermediate layer (middle level) (302) is low echo.
The echo pattern obtained be used to calculate the expansion waveform, because can be observed that, such as institute in Fig. 3
The echo obtained in different zones from artery shown is different.
The remote wall and nearly wall of artery can be separated by implementing back gate tracking.These echoes are identified with
Just area of interest is found in acquired signal, there, the anatomical structure of artery can be located in the region.In order to from
Area of interest is identified in echo pattern, the probabilistic method of such as maximum-likelihood method etc is used.First, sliding window is utilized
Mouthful method, obtains the energy diagram of Setting signal, and determines ceiling capacity region, and from for different patients these are of interest
Region in choose multiple features throughout multiple frames.By obtaining average and covariance, obtain special using gauss hybrid models
Levy data.When providing test frame, being established under the background of the model of the possibility that provides area of interest, to choose special
Levy and it is tested.Single stage process (single class based on such as wall level method (wall class approach) etc
Approach) data are classified.This method using the cutoff value of possibility come to wall level distributing point.
In formula,
The size of d- characteristic vectors
C- covariance matrixes
μ-Gauss mean value
The characteristic vector of x- test points
In addition, change of the blood flow during contraction and diastole causes the change of arterial elasticity.The elastic change is in artery
Diameter change in terms of display.Based on obtained echo is moved because of wall, continuous signal frame is analyzed, and moves
The expansion waveform of arteries and veins is moved the difference between remote wall motion with nearly wall and calculated.
In view of in two continuous echoes obtained obtained in thing, i-ththObtain in thing, NWi(t) it is that nearly wall is returned
Ripple, and FWi(t) it is remote wall echo.Now, the nearly wall echo and remote wall echo obtained in following iteration is represented by：
NWi+1(t)=NWi(t±Гnw)
FWi+1(t)=FWi(t±Гfw)
Wherein ГfwAnd ГnwIt is the offset in nearly wall echo and remote wall echo.Echo tracking is related to estimation, and these offset
Amount and the movement for therefore following echo.In order to estimate time offset of the echo between thing is continuously acquired, skew is employed
And search method, and this method corresponds to calculating signal NWiAnd NW (t)i+1(t) it is preferable for the maximum cross-correlation value between
, and by offset ГfwAnd ГnwIt is estimated as the time of the maximum corresponding to cross-correlation.
Once it is determined that delay, is based on velocity of sound (V) to calculate wall motion
dnw(i)=0.5*v* [Γnw(i)+Γnw(i-1)]
dfw(i)=0.5*v* [Γfw(i)+Γfw(i-1)]
Asrteriectasia waveform is moved the difference between remote wall motion with nearly wall and calculated, and is given by following formula
Go out：
Δ d (i)=dfw(i)-dnw(i)
T=(i/fprf) is substituted into, expansion waveform Δ d (t) is confirmed as follows：
Δ d (t)=dfw(t)-dnw(t)
By above-mentioned expansion waveform, peak to peak expansion value can be calculated, it can be used for measuring other arterial compliance measurements
Value.
Fig. 4 shows that sample expands waveform, and it represents the change of the wall diameter D (mm) by successive frame on sample S (#)
Change.
The pressure change in artery is preferably shown by the change of the cross section of artery.It is used as the function of time
Arterial wall cross section is further calculated based on expansion waveform by following equation：
Functional relation between blood pressure waveform p (t) and arterial wall cross section A (t) sets up as follows：
P (t)=poeγA(t)Formula (2)
In formula, p0It is constant, and γ is different between multiple arteries of patient and between multiple patients.Need
Inquiry table and artery model measure the corresponding γ of artery of interest.Recognition unit (104) as shown in Figure 1 is provided should
Input is to estimate artery and the specific γ values of artery, to carry out more accurate pressure waveform estimation.
By formula (2), pressure waveform can be calculated, and can be to arterial systolic blood pressure, auterial diastole pressure and mean arterial pressure
Estimated.Therefore, it is possible to continuously detect the blood pressure of artery of interest using noninvasive and non-imaged method.
Because the change in the diameter and pressure related to artery of interest is obtainable, therefore can be as follows to such as
Other arterial compliance measured values of modulus of elasticity, artery distensibility, arterial compliance and hardenability value etc are calculated, formula
In, PsIt is systolic pressure and PdIt is diastolic pressure.
Modulus of elasticity
Artery distensibility
Arterial compliance
Hardenability value
Complied with this invention therefore provides the localised blood pressure for artery of interest and other arterial parameters and artery
The continuous measurement of property measured value.
Some features of the present invention have only clearly been illustrated and described herein, and those skilled in the art will expect
Many modifications and changes.The present invention is not limited to preferred embodiment described here in this manual.It will be noted that
It is that the present invention is explained by exemplary embodiment, and neither in detail nor restricted.The present invention
The some aspects not being described in detail herein in this specification have obtained fully understanding for those skilled in the art.Equally,
In the case of any be applicable, the term as used herein in this manual for being related to singulative also includes its plural number, and
Vice versa.Any related amendments or change not specifically described in the specification are in fact interpreted to be in this hair
In bright scope.Appended claims are intended to cover all this modifications and changes in the scope of the present invention.
Thus, it will be appreciated by those skilled in the art that the present invention can be showed in other specific forms, and do not take off
From the spirit or essential attributes of the present invention.Presently disclosed embodiment is accordingly regarded as all being illustrative in all respects, and
It is nonrestrictive.The scope of the present invention is by appended claims rather than described above indicated, implication, boundary in the present invention
All changes in the range of limit and its equivalent, which are intended to, to be covered in wherein.
Claims (17)
1. a kind of system for measuring arterial parameters using ultrasound, the system includes：
Signal element, the signal element is used to provide radio frequency (RF) ultrasonic signal and demodulation RF ultrasonic signals and from thus
The relative data of the signal obtained；
Detection unit, the detection unit is used for the presence for detecting the blood flow in artery；
Recognition unit, the recognition unit is used to recognize the artery；
Processing unit, the processing unit is used to handle the data, and for providing the expansion waveform of the artery；With
Estimation unit, the estimation unit is used to estimate at least one in multiple local intra-arterial parameters of the artery
Meter.
2. the system as claimed in claim 1, wherein, the signal element includes into multiple transducers member of grid configuration arrangement
Part.
3. system as claimed in claim 2, wherein, the multiple element of transducer is either individually or collectively operated, to provide
The RF ultrasonic signal related to artery.
4. the system as claimed in claim 1, wherein, the processing unit is provided for determining the fortune of the tube wall of the artery
The motion of dynamic and its diameter change.
5. the system as claimed in claim 1, wherein, the recognition unit includes show one or more arteries one or many
Individual model.
6. the system as claimed in claim 1, wherein, the processing unit is provided for the expansion wave from the artery
Shape obtains pressure waveform.
7. the system as described in claim 1,5 and 6, wherein, the processing unit is provided for the mould using the artery
Type, in the case where identifying the pressure waveform of the artery, draws the expansion waveform of the artery.
8. the system as claimed in claim 1, wherein, the estimation unit is provided for such as localised blood pressure, systole phase
At least one in the local intra-arterial parameter of peak velocity (PSV), pulse wave number (PWV), arterial compliance measured value etc
It is individual to be estimated.
9. system as claimed in claim 8, wherein, the arterial compliance measured value include modulus of elasticity, artery distensibility,
Arterial compliance, hardenability value.
10. the system as described in any one of preceding claims, wherein, the system is the base for measuring arterial parameters
In non-imaged and noninvasive system.
11. a kind of be used to include using the method for ultrasonic measurement arterial parameters, methods described：
Radio frequency (RF) ultrasonic signal and demodulation RF ultrasonic signals are provided by signal element and from the signal thus obtained
Relative data；
The presence of the blood flow in artery is detected by detection unit；
The artery is recognized by identifying device；
By data described in processing unit processes and provide the expansion waveform of the artery；And
At least one in multiple local intra-arterial parameters of the artery is estimated by estimation unit.
12. method as claimed in claim 11, wherein, the motion for handling the tube wall for including determining the artery and it
The motion of diameter change.
13. method as claimed in claim 11, wherein, the processing includes obtaining from the expansion waveform of the artery
Pressure waveform.
14. method as claimed in claim 11, wherein, the model handled using the artery, identifying
In the case of the pressure waveform for stating artery, the expansion waveform of the artery is drawn.
15. the method as described in any one of preceding claims 11 to 14, wherein, methods described be a kind of non-imaged,
Noninvasive and continuous method, it is used for such as localised blood pressure, peak systolic flow velocity (PSV), pulse wave number (PWV) and bag
Include the local intra-arterial parameter of the arterial compliance measured value of modulus of elasticity, artery distensibility, arterial compliance, hardenability value etc
Estimated.
16. a kind of computer program product, including when performing on a computer processor, for implementing as claim 11 is arrived
The code device of method described in 15.
17. a kind of computer-readable medium, including computer program product as described in claim 16.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN6458CH2014 | 2014-12-22 | ||
| IN6458/CHE/2014 | 2014-12-22 | ||
| PCT/IB2015/059391 WO2016103087A1 (en) | 2014-12-22 | 2015-12-07 | A system and a method for measuring arterial parameters |
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| Publication Number | Publication Date |
|---|---|
| CN107106125A true CN107106125A (en) | 2017-08-29 |
| CN107106125B CN107106125B (en) | 2024-02-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201580070187.5A Active CN107106125B (en) | 2014-12-22 | 2015-12-07 | System and method for measuring arterial parameters |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20170333006A1 (en) |
| EP (1) | EP3236858B1 (en) |
| JP (1) | JP6865685B2 (en) |
| CN (1) | CN107106125B (en) |
| WO (1) | WO2016103087A1 (en) |
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| CN107564072A (en) * | 2017-08-30 | 2018-01-09 | 无锡海鹰电子医疗系统有限公司 | Pulse Doppler image processing method and device |
| CN107898453A (en) * | 2017-12-01 | 2018-04-13 | 陈继红 | For monitoring the portable set of internal arteriovenous fistula |
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| JP6825341B2 (en) * | 2016-12-13 | 2021-02-03 | セイコーエプソン株式会社 | Measuring device, blood pressure measuring device and measuring method |
| RU2019130127A (en) * | 2017-02-27 | 2021-03-29 | Конинклейке Филипс Н.В. | GUIDELINES FOR VENOPUNCTION AND INTRODUCTION OF THE INTRAARTERIAL CATHETER THROUGH AMPLIFIED SIGNAL CHANGE |
| WO2022070206A1 (en) * | 2020-09-30 | 2022-04-07 | Healthcare Technology Innovation Centre | Augmented multimodal flow mediated dilatation |
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| CN107564072B (en) * | 2017-08-30 | 2020-10-16 | 无锡海鹰电子医疗系统有限公司 | Pulse Doppler image processing method and device |
| CN107898453A (en) * | 2017-12-01 | 2018-04-13 | 陈继红 | For monitoring the portable set of internal arteriovenous fistula |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6865685B2 (en) | 2021-04-28 |
| WO2016103087A1 (en) | 2016-06-30 |
| EP3236858A1 (en) | 2017-11-01 |
| EP3236858B1 (en) | 2020-09-09 |
| US20170333006A1 (en) | 2017-11-23 |
| CN107106125B (en) | 2024-02-13 |
| JP2017538539A (en) | 2017-12-28 |
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