CN107041936A - Big maple ointment - Google Patents

Big maple ointment Download PDF

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Publication number
CN107041936A
CN107041936A CN201710184212.3A CN201710184212A CN107041936A CN 107041936 A CN107041936 A CN 107041936A CN 201710184212 A CN201710184212 A CN 201710184212A CN 107041936 A CN107041936 A CN 107041936A
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big maple
ointment
beeswax
days
maple
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率秀冰
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/28Mercury; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/36Arsenic; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/758Zanthoxylum, e.g. pricklyash
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/904Stemonaceae (Stemona family), e.g. croomia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/35Extraction with lipophilic solvents, e.g. Hexane or petrol ether

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

It is calomel mercurous chloride, catechu, Resina Draconis, big maple, crotons, the tuber of stemona, Chinese prickly ash, the root of Dahurain angelica, cinnabar, borneol, realgar, sulphur, beeswax, the sesame oil being made up of following bulk drug the present invention relates to a kind of big maple ointment.The big maple ointment that the present invention is provided is made by the raw material including calomel mercurous chloride, catechu, Resina Draconis, big maple, crotons, the tuber of stemona, Chinese prickly ash, the root of Dahurain angelica, cinnabar, borneol, realgar, sulphur, beeswax and sesame oil, suitable for the treatment of scabies, the big maple ointment uses less flavour of a drug, pass through reasonable compatibility, so that effect of the ingredients in terms of for scabies mutually strengthens, obvious synergy is shown.

Description

Big maple ointment
Technical field
The present invention relates to a kind of desinsection anti-pruritic formulation, more particularly to a kind of big maple ointment.
Background technology
Scabies is common skin diseases in people's daily life, and its pathogenic factor does not note individual's skin health mostly, often The how intensive place of people is contacted, itch mite is felt again and is caused, this disease morbidity is rapid, and the delay time is long, easily recurrence.Patient is disturbed by it deeply, shadow Ring normal life rest.This sick medication of western medical treatment is single, and effect is not good, develops such a preparation for solving clinical application list One, remove disease and disturb great significance.
Recorded for the scabies traditional Chinese medical science early in the inscriptions on bones or tortoise shells for being just related to " scabies " in 14th century of Christian era, the Sui Dynasty《All pathogeny marquis opinion-whirlpools Sore is waited》To scabies to there is more detailed discussion:" being born in scabies between brothers, dye is gradually given birth to as body, and itching has pus more." descendant according to Prove in detail, it is that daily life is careless to get to the bottom of sb.'s illness, and sarcoptic mite is contacted, the damp and hot phase of worm poison is fought, caused by the poly- skin of knot.Accordingly principle and develop Go out the big maple ointment of desinsection anti-pruritic formulation.
The content of the invention
The technical problems to be solved by the invention are:There is provided a kind of big maple ointment of desinsection anti-pruritic formulation, it is adaptable to scabies The treatment of sore.
A kind of big maple ointment, is made up of following bulk drug:Calomel mercurous chloride, catechu, Resina Draconis, big maple, crotons, hundred Portion, Chinese prickly ash, the root of Dahurain angelica, cinnabar, borneol, realgar, sulphur, beeswax, sesame oil.
It is preferred that, it is made up of following bulk drug:Calomel mercurous chloride 5-10g, catechu 5-10g, Resina Draconis 5-10g, big maple 25- 35g, crotons 25-35g, tuber of stemona 40-50g, Chinese prickly ash 90-100g, root of Dahurain angelica 50-55g, cinnabar 50-55g, borneol 38-45g, realgar 90-100g, sulphur 90-100g, beeswax 600g, sesame oil 3400g.
It is preferred that, it is made up of following bulk drug:Calomel mercurous chloride 5g, catechu 5g, Resina Draconis 10g, big maple 30g, crotons 30g, tuber of stemona 50g, Chinese prickly ash 100g, root of Dahurain angelica 50g, cinnabar 50g, borneol 40g, realgar 100g, sulphur 100g, beeswax 600g, sesame oil 3400g。
The preparation method of the big maple ointment is:
1)Immersion:According to selected prescription for medicine, by big maple, crotons, the tuber of stemona, Chinese prickly ash, the root of Dahurain angelica, cinnabar, realgar, sulphur sesame oil Immersion, soak time is with spring and autumn seven days, five days summers, ten days winters;
2)Explosive is wasted lamp oil by not sleeping at night:Sesame oil and the medicine soaked are put into pot together, has just started 20 minutes with high heat, has then been changed to Slow fire, is during which turned in oil cauldron with ash rod and slightly stirred, and treats that medicine boils shrivelled heavy oily bottom, immediately by oil cauldron from fire, is obtained Medicine oil;
3)Dissolve beeswax:Medicine oil is poured into the iron basin equipped with beeswax by 60 mesh sieves, is stirred continuously to beeswax to melt completely and is Only, when temperature drops to about 60 degree or so, the powder that calomel mercurous chloride, catechu, blood dragon exhaust is put into, is stirred, wait cooling completely;
4)It is heated to melting every the iron basin for filling ointment is placed on gas range after two days, is then sieved through filter by 150 mesh iron Into another iron basin, borneol is added after cooling, big maple ointment is produced, is respectively placed in instrument standby in small container.
Application method:Affected part is smeared outside the big maple ointment of external application preparation of preparation, three times a day, is treated within three days, three days not Have a bath, a bath is had after three days and then after with medicine-feeding three days, be weekly a course for the treatment of.
The big maple ointment that the present invention is provided is by including calomel mercurous chloride, catechu, Resina Draconis, big maple, crotons, the tuber of stemona, Chinese prickly ash, white The root of Dahurian angelica, cinnabar, borneol, realgar, sulphur, the raw material of beeswax and sesame oil are made, it is adaptable to which the treatment of scabies, the big maple ointment is used Less flavour of a drug, pass through reasonable compatibility so that effect of the ingredients in terms of for scabies mutually strengthens, and show substantially Synergy.
Embodiment
With reference to embodiment, the present invention is further illustrated.
Embodiment 1 prepares big maple ointment
It is formulated and is:Calomel mercurous chloride 5g, catechu 5g, Resina Draconis 10g, big maple 30g, crotons 30g, tuber of stemona 50g, Chinese prickly ash 100g, the root of Dahurain angelica 50g, cinnabar 50g, borneol 40g, realgar 100g, sulphur 100g, beeswax 600g, sesame oil 3400g.
Preparation method is:1)Immersion:According to selected prescription for medicine, by big maple, crotons, the tuber of stemona, Chinese prickly ash, the root of Dahurain angelica, cinnabar, Realgar, sulphur are soaked with sesame oil, and soak time is with spring and autumn seven days, five days summers, ten days winters;
2)Explosive is wasted lamp oil by not sleeping at night:Sesame oil and the medicine soaked are put into pot together, has just started 20 minutes with high heat, has then been changed to Slow fire, is during which turned in oil cauldron with ash rod and slightly stirred, and treats that medicine boils shrivelled heavy oily bottom, immediately by oil cauldron from fire, is obtained Medicine oil;
3)Dissolve beeswax:Medicine oil is poured into the iron basin equipped with beeswax by 60 mesh sieves, is stirred continuously to beeswax to melt completely and is Only, when temperature drops to about 60 degree or so, the powder of calomel mercurous chloride, catechu, resina draconis powder is put into, is stirred, wait cooling completely;
4)It is heated to melting every the iron basin for filling ointment is placed on gas range after two days, is then sieved through filter by 150 mesh iron Into another iron basin, borneol is added after cooling, big maple ointment is produced, is respectively placed in instrument standby in small container.
Application method:Affected part is smeared outside the big maple ointment of external application preparation of preparation, three times a day, is treated within three days, three days not Have a bath, a bath is had after three days and then after with medicine-feeding three days, be weekly a course for the treatment of.
Embodiment 2 prepares big maple ointment
It is formulated and is:Calomel mercurous chloride 8g, catechu 8g, Resina Draconis 8g, big maple 35g, crotons 33g, tuber of stemona 48g, Chinese prickly ash 95g, root of Dahurain angelica 52g, Cinnabar 52g, borneol 40g, realgar 100g, sulphur 100g, beeswax 600g, sesame oil 3400g.
Preparation method be the same as Example 1.
Embodiment 3 prepares big maple ointment
It is formulated and is:Calomel mercurous chloride 6g, catechu 6g, Resina Draconis 6g, big maple 30g, crotons 30g, tuber of stemona 45g, Chinese prickly ash 100g, root of Dahurain angelica 55g, Cinnabar 55g, borneol 40g, realgar 100g, sulphur 100g, beeswax 600g, sesame oil 3400g.
Preparation method be the same as Example 1.
Specific case observation of curative effect:
Experimental example 1
Patient Lee, male, 16 years old, Chengwu County Bai Fu people from towns.
Main suit:Patient's hand seam, oxter, bilateral femoribus internus night itch are aggravated 5 days January
Present illness history:Patient because of skin night itch to local area hospitalize, hung up one's hat collective place before 20 days according to patient Relative humidity in house, house, bed clothes are changed not in time, and physical examination interdigital space of hand and pars inguinalis can be seen that needle point size papule And part black wire tunnel, it is diagnosed as scabies.It is recommended that patient isolates in time, antipruritic for oral administration is given, the sulphur of external application 20% is soft Cream is put on the skin outside, daily 2-3 times, every 5 days courses for the treatment of, two courses for the treatment of is used in conjunction, symptom has been alleviated.One week cause eats capsicum and causes disease Shape recurs and itch is more violent than before, without alleviation, is treated after with above-mentioned drug therapy with here is come.
Past medical history:Nothing
Physical examination T:36.3 P:70 beats/min of R:20 beats/min of BP:120/80mmHg, spirit can, indagation cooperation, whole skin without Xanthochromia, oedema, the positive great circle of dicoria, whole body superficial lymph knot are without exception, double lung percussion voicelesss sound, and breathing is normal, no rale, the apex of the heart Beating and border of cardiac dullness are normal, and rule is neat, and no noise, abdomen is soft, no tenderness, percussion pain, Blumberg's sign.Do not lay one's hand on and liver,spleen,kidney.Spleen and Bilateral Renal area is without tenderness, percussion pain.Backbone is normal.Between both hands refer to and oxter, pars inguinalis can be seen that black wire tunnel, 2- 3 millimeters long, in tunnel, cecum color is scarlet or light red, and skin surface scratch is obvious.
Diagnosis:Scabies
Patient's tongue is red after being admitted to hospital, yellow and greasy fur, rapid pulse, and dialectical to accumulate malicious card to be damp and hot, treatment is beautiful with the agent of oral medicine powde wind clearing heat and promoting diuresis Screen dissipates smears affected part outside plus-minus, one portion per day, the big maple ointment of external application preparation of preparation, three times a day, treats within three days, three days Do not have a bath, a bath is had after three days and then after with medicine-feeding three days, further consultation after medication, the whole shanks in interdigital space of hand and oxter are without any Discomfort, pars inguinalis non-tunnel and papule but it is even have slight night itch, subtract traditional Chinese medicine for oral administration, smeared three days after with outside self-control preparation Until symptom disappears completely.Further consultation is without recurrence after January.
Experimental example 2
Patient Zhang, male, 35 years old, Jinxiang County Zhang Zhai people from village
Main suit:Patient's scrotum portion's itch is aggravated 10 days January with hard tubercle
Present illness history:There is interdigital space of hand, pars inguinalis night itch in patient before January, after voluntarily being treated 3 days with Claritin Effect is not good, is treated with to local county people's hospital, is diagnosed as scabies, gives 20% sulfur ointment after one week treatment effect and fails to understand It is aobvious, after use instead and smeared outside 25% benzyl benzoate cream, interdigital space of hand and pars inguinalis itch are alleviated after one week, but scrotum position goes out Existing hard tubercle, after aggravate because of symptoms of alcohol consumption, after treating symptom without alleviation with top, with carrying out here treatment.
Past medical history:Nothing
Physical examination T:38.0 P:75 beats/min of R:25 beats/min of BP:120/75mmHg, spirit can, lamprophonia, indagation cooperation, entirely Body skin is without xanthochromia, oedema, and the positive great circle of dicoria, whole body superficial lymph knot is without exception, double lung percussion voicelesss sound, and breathing is normal, nothing Rale, apex beat and border of cardiac dullness are normal, and rule is neat, and no noise, abdomen is soft, no tenderness, percussion pain, Blumberg's sign.Do not lay one's hand on and liver, Spleen, kidney.Spleen and Bilateral Renal area are without tenderness, percussion pain.Backbone is normal.There are more than ten tubercles differed in size in scrotum portion, above grabs Trace simultaneously has a little incrustation.
Diagnosis:Scabies tubercle
Patient's red tongue body after being admitted to hospital, tongue is thin white, faint and rapid pulse, dialectical to accumulate in wet poison, treats with clearing heat and detoxicating, the antipruritic Chinese medicine of desinsection The big maple ointment of trituration twice daily, 10 minutes every time, is smeared twice daily in decoction kuh-seng soup plus-minus washout affected part outside, three days Have a bath once, be weekly a course for the treatment of, further consultation tubercle largely disappears after one week, leaves several larger tubercles that compare incomplete Disappear with night slight itch, former prescription adds the stronger chinese medicine stemona tuber washout of insecticidal power, is smeared after with outside big maple ointment.After one week Further consultation symptom is wholly absent.Patient is advised to avoid eating tobacco and wine, the product of pungent stimulation.Follow-up is without recurrence after January.
The specific embodiment of the present invention is not construed as limiting the invention, every similar structure and change using the present invention Change, within the scope of the present invention.

Claims (4)

1. a kind of big maple ointment, it is characterised in that:It is made up of following bulk drug:Calomel mercurous chloride, catechu, Resina Draconis, big maple, Crotons, the tuber of stemona, Chinese prickly ash, the root of Dahurain angelica, cinnabar, borneol, realgar, sulphur, beeswax, sesame oil.
2. big maple ointment according to claim 1, it is characterised in that:It is made up of following bulk drug:Calomel mercurous chloride 5- 10g, catechu 5-10g, Resina Draconis 5-10g, big maple 25-35g, crotons 25-35g, tuber of stemona 40-50g, Chinese prickly ash 90-100g, the root of Dahurain angelica 50-55g, cinnabar 50-55g, borneol 38-45g, realgar 90-100g, sulphur 90-100g, beeswax 600g, sesame oil 3400g.
3. big maple ointment according to claim 1, it is characterised in that:It is made up of following bulk drug:Calomel mercurous chloride 5g, youngster Tea 5g, Resina Draconis 10g, big maple 30g, crotons 30g, tuber of stemona 50g, Chinese prickly ash 100g, root of Dahurain angelica 50g, cinnabar 50g, borneol 40g, hero Yellow 100g, sulphur 100g, beeswax 600g, sesame oil 3400g.
4. according to the preparation method of big maple ointment according to any one of claims 1 to 3, it is characterised in that:1)Immersion:Press According to selected prescription for medicine, big maple, crotons, the tuber of stemona, Chinese prickly ash, the root of Dahurain angelica, cinnabar, realgar, sulphur are soaked with sesame oil, soak time With spring and autumn seven days, five days summers, ten days winters;
2)Explosive is wasted lamp oil by not sleeping at night:Sesame oil and the medicine soaked are put into pot together, has just started 20 minutes with high heat, has then been changed to Slow fire, is during which turned in oil cauldron with ash rod and slightly stirred, and treats that medicine boils shrivelled heavy oily bottom, immediately by oil cauldron from fire, is obtained Medicine oil;
3)Dissolve beeswax:Medicine oil is poured into the iron basin equipped with beeswax by 60 mesh sieves, is stirred continuously to beeswax to melt completely and is Only, when temperature drops to about 60 degree or so, the powder that calomel mercurous chloride, catechu, blood dragon exhaust is put into, is stirred, wait cooling completely;
4)It is heated to melting every the iron basin for filling ointment is placed on gas range after two days, is then sieved through filter by 150 mesh iron Into another iron basin, borneol is added after cooling, big maple ointment is produced, is respectively placed in instrument standby in small container.
CN201710184212.3A 2017-03-24 2017-03-24 Big maple ointment Pending CN107041936A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101559131A (en) * 2009-05-05 2009-10-21 周大红 Traditional Chinese medicinal composition for treating scabies and preparation method thereof
CN103372109A (en) * 2012-04-16 2013-10-30 韩凤云 Outer application drug for treating scabies

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101559131A (en) * 2009-05-05 2009-10-21 周大红 Traditional Chinese medicinal composition for treating scabies and preparation method thereof
CN103372109A (en) * 2012-04-16 2013-10-30 韩凤云 Outer application drug for treating scabies

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
上海第一医学院,华山医院皮肤科编著: "《中医皮肤病诊疗参考》", 31 December 1975, 上海第一医学院,华山医院皮肤科 *
于淞: "《皮肤科临床外用药物》", 30 November 1975, 第97页 *
赵新安: "疥见消外搽治疥疮", 《陕西中医》 *

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