CN107029354A - The impact signal detection method of heart defibrillator - Google Patents

The impact signal detection method of heart defibrillator Download PDF

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CN107029354A
CN107029354A CN201611090903.9A CN201611090903A CN107029354A CN 107029354 A CN107029354 A CN 107029354A CN 201611090903 A CN201611090903 A CN 201611090903A CN 107029354 A CN107029354 A CN 107029354A
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detection method
signal
conversion
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value
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金范起
金良植
林俊植
辛秉柱
林钟佑
王宝现
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LIMITED Co
University of Hong Kong HKU
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39Heart defibrillators
    • A61N1/3925Monitoring; Protecting
    • A61N1/3937Monitoring output parameters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39Heart defibrillators
    • A61N1/395Heart defibrillators for treating atrial fibrillation

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  • Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

The impact signal detection method of heart defibrillator according to an embodiment of the invention may include steps of:Receive electrocardiosignal;First conversion is carried out to the electrocardiosignal of the receiving;Second is carried out to the electrocardiosignal by the described first conversion to convert;Utilize the signal of change characteristic value by the second conversion;And the characteristic value of the calculating is used as input value and impact signal is detected by Weighted Fuzzy membership function.

Description

心脏除纤颤器的冲击信号检测方法Shock signal detection method of cardiac defibrillator

技术领域technical field

本发明涉及一种能够短缩对心搏骤停患者施加冲击的心脏除纤颤器在进行除颤之前的时间的心脏除纤颤器的冲击信号检测方法。The present invention relates to a shock signal detection method of a cardiac defibrillator capable of shortening the time before defibrillation is performed by the cardiac defibrillator that applies a shock to a cardiac arrest patient.

背景技术Background technique

很多人因心脏骤停(Sudden Cardiac Arrest,SCA)而死亡,其中大部分的死亡原因是由于威胁生命的心律失常。当出现威胁生命程度的深刻心律失常时,患者的生存率与迅速应急措施紧密相联。由此,自动体外心脏去颤器(Automated ExternalDefibrillator)的普及广泛扩散。上述自动体外心脏去颤器是一种自动判断是否需要施加电冲击后施加电冲击,而无需专业医务人员判断心电信号的装置。Many people die from sudden cardiac arrest (Sudden Cardiac Arrest, SCA), most of which are due to life-threatening cardiac arrhythmias. When profound cardiac arrhythmias occur on a life-threatening level, patient survival is closely linked to prompt response. As a result, the spread of automated external defibrillators (Automated External Defibrillators) has spread widely. The above-mentioned automatic external defibrillator is a device that automatically judges whether it is necessary to apply an electric shock and then applies an electric shock without professional medical personnel judging the electrocardiographic signal.

与美国等其他国家的心搏骤停患者相比,韩国国内心搏骤停患者的生存率是很低的,这是因为没有足够的允许迅速应急措施的环境。因此,优选的是,不仅是救护人员而是一般人也利用自动体外心脏去颤器来在现场对患者进行自动心脏除颤之后,将患者移动到医院。Compared with cardiac arrest patients in other countries such as the United States, the survival rate of cardiac arrest patients in Korea is very low because there is not enough environment that allows rapid emergency measures. Therefore, it is preferable that not only emergency personnel but also ordinary people use an automatic external defibrillator to automatically defibrillate a patient on the spot and then move the patient to a hospital.

威胁生命程度的心律失常的类型中最常见的是粗室颤(coarse ventricularfibrillation,coarse VF)或快速室性心动过速(rapid ventricular tachycardia,rapidVT)。在出现上述coarse VF或rapid VT的心搏骤停患者的情况下,只有在10分钟以内进行除颤才能生存,随着时间经过,每分钟7至10%的生存率降低,从而,通过利用自动体外心脏去颤器来快速进行除颤来能够提高生存率。The most common type of life-threatening arrhythmia is coarse ventricular fibrillation (coarse VF) or rapid ventricular tachycardia (rapid ventricular tachycardia, rapidVT). In the case of a cardiac arrest patient with the above-mentioned coarse VF or rapid VT, only defibrillation within 10 minutes can survive, and as time passes, the survival rate decreases by 7 to 10% per minute. External defibrillators provide rapid defibrillation to improve survival.

因此,为了执行除颤,先需要检测如coarse VF及rapid VT等冲击信号的步骤。到目前为止用来检测上述冲击信号的算法中,在2007年发表的延时(Time-Delay)算法通过在8秒之间的心电信号检测coarse VF。而且,参数集(Parameter Set)算法通过在10秒之间的心电信号可以检测coarse VF、rapid VT、NSR及N(其他心律失常)。在2008年发表的径向基函数(Radial Basis Function,RBF)检测算法可以检测到VF/VT和NSR/N而争取了较好结果,但因预先选择用于实验的心电信号而具有普遍性较低的问题。Therefore, in order to perform defibrillation, a step of detecting shock signals such as coarse VF and rapid VT is first required. Among the algorithms used to detect the above-mentioned shock signals so far, the Time-Delay algorithm published in 2007 detects coarse VF through ECG signals between 8 seconds. Moreover, the Parameter Set algorithm can detect coarse VF, rapid VT, NSR and N (other arrhythmias) through ECG signals within 10 seconds. The radial basis function (RBF) detection algorithm published in 2008 can detect VF/VT and NSR/N and strive for better results, but it is universal because of the pre-selection of ECG signals for experiments lower question.

如上所述,人们一直致力于对用来缩短执行除颤所需的时间的方法的研宄。在实际上,为了施加冲击信号而从在检测心电信号之前充电电容器的算法也被开发出来,但缩短心电信号检测时间本身并提高检测准确度的方法是还没公开的。As described above, research has been devoted to methods for shortening the time required to perform defibrillation. In practice, an algorithm for charging a capacitor before detecting an ECG signal in order to apply a shock signal has also been developed, but a method of shortening the ECG signal detection time itself and improving detection accuracy has not been disclosed.

发明内容Contents of the invention

本发明的目的在于提供一种能够短缩对心搏骤停患者施加冲击的心脏除纤颤器在进行除颤之前的时间的心脏除纤颤器的冲击信号检测方法。An object of the present invention is to provide a shock signal detection method of a cardiac defibrillator capable of shortening the time until the defibrillator performs defibrillation, which applies a shock to a patient in cardiac arrest.

根据本发明的实施例的心脏除纤颤器的冲击信号检测方法可以包括如下步骤:接受心电信号;对所述接受的心电信号进行第一变换;对经过所述第一变换的心电信号进行第二变换;利用所述经过第二变换的信号计算特征值;及将所述计算的特征值用作输入值并通过加权模糊隶属度函数检测冲击信号。The shock signal detection method of a cardiac defibrillator according to an embodiment of the present invention may include the following steps: receiving an electrocardiographic signal; performing a first transformation on the accepted electrocardiographic signal; performing a second transformation on the signal; calculating a feature value using the second transformed signal; and using the calculated feature value as an input value and detecting a shock signal through a weighted fuzzy membership function.

所述接受的信号可以为数字形式信号。The received signal may be a signal in digital form.

所述第一变换可以为小波变换。The first transform may be wavelet transform.

所述第二变换可以为延时变换(Time Delay Transform)。The second transformation may be a time delay transformation (Time Delay Transform).

所述延时变换可以由式“Y(x)=X(x+0.5)-X(x)”实现,在式中,所述X(x)可以为经过第一变换的信号,Y(x)可以为经过第二变换的信号。The delay transformation can be realized by the formula "Y(x)=X(x+0.5)-X(x)", in which, the X(x) can be the first transformed signal, Y(x ) may be a second transformed signal.

所述心脏除纤颤器的冲击信号检测方法还可包括通过利用所述经过第二变换的信号来判断是否心搏停止的步骤。The shock signal detection method of the cardiac defibrillator may further include a step of judging whether the cardiac arrest is by using the second converted signal.

所述判断是否心搏停止的步骤可以包括通过利用所述经过第二变换的信号值的绝对值的总和来进行判断的步骤。The step of judging whether cardiac arrest may include a step of judging by using a sum of absolute values of the second transformed signal values.

所述判断是否心搏停止的步骤可以包括通过利用所述经过第二变换的信号值之间的距离来进行判断的步骤。The step of judging whether cardiac arrest may include a step of judging by using the distance between the second transformed signal values.

如果判断是否心搏停止的所述判断结果为否,就可以进行所述计算特征值的步骤。If the judgment result of whether the cardiac arrest is judged is negative, the step of calculating the characteristic value may be performed.

所述计算特征值的步骤可以包括计算在所述经过第二变换的信号值中在预先设定的振幅区间内的值之间的平均距离的步骤。The step of calculating the characteristic value may include the step of calculating an average distance between values within a preset amplitude interval in the second transformed signal value.

所述计算特征值的步骤可以包括计算连接所述经过第二变换的信号值的直线的倾斜度的标准偏差的步骤。The step of calculating the characteristic value may include the step of calculating the standard deviation of the slope of the straight line connecting the second transformed signal values.

所述计算特征值的步骤可以包括计算所述经过第二变换的信号的峰值的个数、峰值的前后值、包含于预先设定的范围的峰值的标准偏差中的至少一个的步骤。The step of calculating the characteristic value may include calculating at least one of the number of peaks, the values before and after the peaks, and the standard deviation of the peaks included in the preset range of the second transformed signal.

所述计算的特征值可以为七个。The calculated eigenvalues may be seven.

根据本发明的一个实施例的冲击信号检测方法具有如下效果:通过在7秒内检测到根据心电信号的冲击信号来能够缩短施加除颤冲击信号所需的时间。The shock signal detection method according to one embodiment of the present invention has the effect that the time required for applying a defibrillation shock signal can be shortened by detecting a shock signal according to an electrocardiographic signal within 7 seconds.

附图说明Description of drawings

图1为示出根据本发明的一个实施例的冲击信号检测方法的流程图。FIG. 1 is a flow chart illustrating a method for detecting an impact signal according to an embodiment of the present invention.

图2为示出在根据本发明的一个实施例的冲击信号检测方法中初始输入信号的图表。FIG. 2 is a graph illustrating an initial input signal in a shock signal detection method according to an embodiment of the present invention.

图3a为示出在根据本发明的一个实施例的冲击信号检测方法中经过第一变换的信号的图表。Fig. 3a is a graph showing a first transformed signal in a shock signal detection method according to an embodiment of the present invention.

图3b为示出在根据本发明的一个实施例的冲击信号检测方法中经过第二变换的信号的图表。Fig. 3b is a graph showing a second transformed signal in the shock signal detection method according to one embodiment of the present invention.

图4a至图4b为示出用于从如图3b所示的经过第二变换的信号检测心搏停止(Asystole)的方法的附图。Figures 4a-4b are diagrams illustrating a method for detecting an asystole (Asystole) from the second transformed signal as shown in Figure 3b.

图5至图10为示出在根据图4a至图4b未检测到心搏停止时为检测冲击信号而计算特征值的示意性方法的附图。FIGS. 5 to 10 are diagrams illustrating schematic methods of calculating characteristic values for detecting shock signals when asystole is not detected according to FIGS. 4 a to 4 b.

具体实施方式detailed description

对于本说明书或本申请中所公开的本发明的各实施例的具体结构说明或具体功能说明仅是为了解释根据发明的各实施例的目的而提供的。因此,根据发明的各实施例可以以各种不同的形式而被实施,且不应被理解为受限于本说明书或本申请中所说明的各实施例。The specific structural descriptions or specific functional descriptions of the various embodiments of the present invention disclosed in this description or this application are provided only for the purpose of explaining the various embodiments of the present invention. Therefore, various embodiments according to the invention may be embodied in various different forms, and should not be construed as being limited to the various embodiments described in this specification or this application.

根据本发明的实施例可进行多种变更,可具有多个形式,在附图中例示特定实施例并在本说明书或申请中予以详细说明。但是,这并非要将根据本发明限定于特定实施例,而应理解为包括本发明的思想及技术范围所包含的所有变更、等同替换以及替代物。Embodiments according to the present invention can be modified in various ways and have various forms, and specific embodiments are illustrated in the drawings and described in detail in this specification or application. However, it is not intended to limit the present invention to specific examples, and it should be understood that all changes, equivalents, and substitutions included in the spirit and technical scope of the present invention are included.

在本发明中,第一和/或第二等术语可用于说明各种组件,但所述组件并不限定于所述术语。所述术语只是用于区分某一组件与其他组件,例如,在不脱离根据本发明的概念的权利保护范围内,第一组件可命名为第二组件,类似地,第二组件可命名为第一组件。In the present invention, terms such as first and/or second may be used to describe various components, but the components are not limited to the terms. The terms are only used to distinguish a certain component from other components. For example, within the protection scope of the concept according to the present invention, the first component can be named as the second component, and similarly, the second component can be named as the second component. a component.

说明某种结构要素“连接于”另一结构要素时,既可理解为直接连接于另一结构要素,也可理解为中间存在另一结构要素。相反地,当说明某种结构要素“直接连接于”另一结构要”时,应理解为中间不存在另一结构要素。另一方面,说明结构要素之间的关系的其他术语,即“…之间”、“就在…之间”、“邻接于…”及“直接邻接于…”等也能够以相同的方式理解。When it is stated that a certain structural element is "connected" to another structural element, it can be understood as being directly connected to another structural element, or as having another structural element in between. Conversely, when it is stated that a certain structural element is "directly connected" to another structural element, it should be understood that there is no other structural element in between. On the other hand, other terms that describe the relationship between structural elements, namely "... "between", "right between", "adjacent to ..." and "directly adjacent to ..." etc. can also be understood in the same way.

在此使用的术语仅出于描述特定实施方式的目的,而并非在限定本发明。如在此所使用的,単数形式在也包括复数形式,除非上下文中另有清楚地指明。还应理解的是,当在此使用术语“包含(comprise)”、“包含(comprising)”,具有(have)”和/或“具有(having)”时,指明所述特征、数字、步骤、操作、元件、部件和/或其组合的存在,但是不排除ー个或多个其他特征、数字、步骤、操作、元件、部件和/或其组合的存在或添加。The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, singular forms also include plural forms unless the context clearly dictates otherwise. It should also be understood that when the terms "comprise", "comprising", "have" and/or "having" are used herein, it means that said features, numbers, steps, The presence of operations, elements, components and/or combinations thereof does not preclude the presence or addition of one or more other features, numbers, steps, operations, elements, components and/or combinations thereof.

在未特别定义的情况下,在这里所使用的包括技术或科学术语在内的所有术语与由本发明所属技术领域的普通技术人员通常理解的意义具有相同的意义。通常所使用的与在词典上定义的相同的术语应解释为具有与相关技术的文脉上具有的意义一致的意义,在本申请中未明确定义的情况下,不解释为理想化或过度形式化的意义。Unless otherwise defined, all terms including technical or scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the present invention belongs. Generally used terms that are the same as those defined in dictionaries should be interpreted as having meanings that are consistent with the contextual meanings of related technologies, and should not be interpreted as idealized or excessive forms if they are not clearly defined in this application meaning of transformation.

以下,参照附图对本发明的优选实施例进行说明,以详细说明本发明。图中,对相同的构成元件标注相同的符号。Hereinafter, preferred embodiments of the present invention will be described with reference to the accompanying drawings to explain the present invention in detail. In the drawings, the same symbols are assigned to the same constituent elements.

图1为示出根据本发明的一个实施例的冲击信号检测方法的流程图。FIG. 1 is a flow chart illustrating a method for detecting an impact signal according to an embodiment of the present invention.

参照图1,根据本发明的一个实施例的冲击信号检测方法可以由冲击信号检测装置实现,且可以通过构成冲击信号检测装置的接受单元、中央控制单元等执行。Referring to FIG. 1 , the shock signal detection method according to one embodiment of the present invention can be implemented by a shock signal detection device, and can be executed by a receiving unit, a central control unit, etc. constituting the shock signal detection device.

首先,从附着于患者身体的电极垫接受心电信号(S101),对所接受的心电信号进行第一变换(S103)。对经过第一变换的信号还进行第二变换(S105)。通过利用经过第二变换的信号来判断是否心搏停止(Asystole)(S107),在判断结果为否时,计算多个特征值(S109)。作为一个例子,所计算的特征值可以为七个。上述特征值成为通过预先学习得到的加权模糊隶属度函数的输入值,可以从加权模糊隶属度函数检测冲击信号(S111)。First, an electrocardiographic signal is received from electrode pads attached to the patient's body (S101), and a first transformation is performed on the received electrocardiographic signal (S103). Perform a second transformation on the first transformed signal (S105). Whether the cardiac arrest (Asystole) is judged by using the second converted signal (S107), and when the judgment result is negative, a plurality of feature values are calculated (S109). As an example, the calculated eigenvalues may be seven. The above-mentioned feature value becomes an input value of a weighted fuzzy membership function obtained through pre-learning, and the shock signal can be detected from the weighted fuzzy membership function (S111).

心搏停止是指因已心停止而无需施加除颤冲击的状态。Asystole is a state in which a defibrillation shock is not required because the heart has stopped.

在现有方法的情况下,通过利用经过第一变换的信号来判定是否心搏停止而计算出六个特征值,但在本发明的情况下,与现有技术的区别特征在于,在基于经过第一变换的信号再进行第二变换之后,基于经过第二变换的信号判定是否心搏停止,计算出七个特征值。并且,判定是否心搏停止的方法也是不同的。以往是通过经过第一变换的信号的峰值点的平均值判定是否心搏停止,但在本发明中,通过输出将经过第二变换的信号的峰值点大小的绝对值的总合和峰值点之间的距离的总合的平均值用作输入值的输入有预先设定的学习过程的加权模糊隶属度函数判定是否心搏停止。In the case of the existing method, six eigenvalues are calculated by using the first converted signal to determine whether the cardiac arrest is present, but in the case of the present invention, the difference from the prior art is that, based on the After the first transformed signal is subjected to the second transformation, whether cardiac arrest is determined based on the second transformed signal, and seven eigenvalues are calculated. In addition, the method of determining whether or not the cardiac arrest is also different. In the past, whether cardiac arrest is judged by the average value of the peak points of the first transformed signal, but in the present invention, by outputting the sum of the absolute values of the peak points of the second transformed signal and the peak point The average value of the sum of the distances between them is used as the input value of the weighted fuzzy membership function with a preset learning process to determine whether cardiac arrest.

上述多个特征值的计算方法可以根据起因于加权模糊隶属度函数的学习结果而决定。The calculation method of the above-mentioned plurality of feature values can be determined based on the learning result due to the weighted fuzzy membership function.

图2为示出在根据本发明的一个实施例的冲击信号检测方法中初始输入信号的图表,图3a为示出在根据本发明的一个实施例的冲击信号检测方法中经过第一变换的信号的图表,图3b为示出在根据本发明的一个实施例的冲击信号检测方法中经过第二变换的信号的图表。Fig. 2 is a graph showing the initial input signal in the shock signal detection method according to one embodiment of the present invention, and Fig. 3a is a signal showing a first transformation in the shock signal detection method according to one embodiment of the present invention Fig. 3b is a graph showing a second transformed signal in the shock signal detection method according to an embodiment of the present invention.

参照图2,如图2所示的图表表示在经过第一变换即哈尔小波(HaarWavelet)变换之前的初始输入信号的一个例子。图3a是表示经过第一变换的信号的图表。经过第一变换的信号还经过第二变换,以成为具有如图3b的图表所示的形式的信号。第二变换可以由下式实现。Referring to FIG. 2, the graph shown in FIG. 2 represents an example of an initial input signal before undergoing a first transformation, Haar Wavelet transformation. Fig. 3a is a diagram representing a first transformed signal. The first transformed signal is also subjected to a second transformation to become a signal having the form shown in the diagram of Fig. 3b. The second transformation can be realized by the following formula.

数学式1Mathematical formula 1

Y(x)=X(x+0.5)-X(x)Y(x)=X(x+0.5)-X(x)

上式中,Y(x)部分表示经过第二变换的信号,X(x)部分表示经过第一变换的信号。上述第二变换是利用延时(Time Delay)实现的。作为一个例子,第二变换可以为延时变换(Time Delay Transform,TDT)。In the above formula, part Y(x) represents the signal after the second transformation, and part X(x) represents the signal after the first transformation. The above-mentioned second conversion is realized by using a time delay (Time Delay). As an example, the second transformation may be a time delay transformation (Time Delay Transform, TDT).

第一变换即小波变换是在信号处理方面通过同时分析在时间上的局部性的特定地点处的频率特性来能够弥补提供全局频率特性信息的傅立叶变换的缺点的方法,非连续小波变换可以将时间-频率信号分离成不同尺度的非连续信号。按d1、d2、d3级的顺序信号的峰值点分布越来越变得简单,从而能够仅显示所需的信号。在上述小波变换结果中,对d3值进行第二变换。The first transform, namely wavelet transform, is a method that can make up for the shortcomings of the Fourier transform that provides global frequency characteristic information by simultaneously analyzing the frequency characteristics at a specific location in time in terms of signal processing. Discontinuous wavelet transform can convert time -Separation of frequency signals into non-continuous signals of different scales. The distribution of the peak points of the signals in the order d1, d2, d3 becomes increasingly simple, so that only the desired signal can be displayed. In the above wavelet transformation result, a second transformation is performed on the d3 value.

图4a至图4b为示出用于从如图3b所示的经过第二变换的信号检测心搏停止(Asystole)的方法的附图。Figures 4a-4b are diagrams illustrating a method for detecting an asystole (Asystole) from the second transformed signal as shown in Figure 3b.

参照图4a和图4b,图4a示出利用绝对值判断是否心搏停止(Asystole)的方法,图4b示出利用信号值之间的距离判断是否心搏停止(Asystole)的方法。如图4a及图4b所示,为了判断是否心搏停止,可以将经过第二变换的信号用作原始信号(Original Signal)。通过如图4a及图4b所示的方法可以判断是否心搏停止(Asystole)。其具体过程如上所述。Referring to Fig. 4a and Fig. 4b, Fig. 4a shows the method of using the absolute value to judge whether the cardiac arrest (Asystole), and Fig. 4b shows the method of using the distance between the signal values to judge whether the cardiac arrest (Asystole). As shown in FIG. 4a and FIG. 4b, in order to determine whether the cardiac arrest is present, the signal after the second transformation can be used as the original signal (Original Signal). Whether cardiac arrest (Asystole) can be judged by the method shown in Fig. 4a and Fig. 4b. Its specific process is as above.

通过如图4a和图4b所示的方法判断是否心搏停止,如果判断结果为是时,就无需施加冲击,判断为不可施加冲击状态,结束随后的步骤,或者,在新的命令或信号被输入的情况下,可以重新反复经过第一变换和第二变换来判断是否心搏停止的步骤。Whether the cardiac arrest is judged by the method shown in Figure 4a and Figure 4b, if the judgment result is yes, there is no need to apply shock, it is judged that the shock state cannot be applied, and the subsequent steps are ended, or, when a new command or signal is received In the case of input, the steps of determining whether cardiac arrest occurs through the first conversion and the second conversion may be repeated again.

图5至图10示出,当判断是否心搏停止的判断结果为否时,为了判断是否可以施加冲击(检测冲击信号)而计算多个特征值的各种示意性方法。5 to 10 show various exemplary methods of calculating a plurality of feature values for judging whether a shock can be applied (detecting a shock signal) when the judgment result of asystole is negative.

图5示出利用相空间重构(Phase Space Reconstruction,PSR)方法计算特征值的一个例子。上述方法是用来基于相空间(Phase Space)分析动态波形或随机信号的方法,其利用对经过第一变换的信号的d3数据进行第二变换而得到的值,在x轴表示当时间t时的振幅单位(amplitude unit)值,在y轴表示当时间t+0.5时的振幅单位(amplitude unit)值,从而获得二维图表,通过此时所表示的框(box)的个数而得到特征值。如图5的上左侧所示,在正常波形(Normal Sinus Rhythm,NSR)的情况下,如下左侧所示占有较小空间,但如上右侧所示,在非正常波形(室颤:VF)的情况下,如下右侧所示占有较大空间。基于所构成的相空间(Phase Space),可以由下式求得特征值(d)。FIG. 5 shows an example of calculating eigenvalues using a phase space reconstruction (Phase Space Reconstruction, PSR) method. The above method is a method for analyzing dynamic waveforms or random signals based on phase space, which uses the value obtained by performing the second transformation on the d3 data of the first transformed signal, and represents the time t on the x-axis The amplitude unit (amplitude unit) value of the y-axis indicates the amplitude unit (amplitude unit) value at time t+0.5, so as to obtain a two-dimensional chart, and the characteristics are obtained by the number of boxes (boxes) represented at this time value. As shown in the upper left of Figure 5, in the case of a normal waveform (Normal Sinus Rhythm, NSR), it occupies a small space as shown in the lower left, but as shown in the upper right, in the case of an abnormal waveform (ventricular fibrillation: VF ) takes up a large space as shown on the right below. Based on the constituted phase space (Phase Space), the eigenvalue (d) can be obtained from the following equation.

数学式2Mathematical formula 2

图6为示出通过峰值点的个数计算特征值的方法的附图。在经过第二变换的心电信号中,可以抽出峰值点的个数。图6的左侧显示在正常波形(Normal Sinus Rhythm,NSR)情况下的峰值点的个数,右侧显示在室颤(VF)的情况下的峰值点的个数,由此可知,有明显差异。将属于整个点的平均值以上的点用作峰值点。上述峰值点的个数被用做特征值。FIG. 6 is a diagram illustrating a method of calculating a feature value by the number of peak points. From the second converted ECG signal, the number of peak points can be extracted. The left side of Fig. 6 shows the number of peak points in the case of normal waveform (Normal Sinus Rhythm, NSR), and the right side shows the number of peak points in the case of ventricular fibrillation (VF). difference. A point above the average value belonging to the entire point is used as a peak point. The number of the above-mentioned peak points is used as a feature value.

在图7的情况下,可以通过利用在峰值点之前侧的两点和后侧的两点来计算特征值。在经过第二变换的信号中找出峰值点而求得在峰值点之前侧的两个值(p1、p2)和后侧的两个值(n1、n2),其中可以将p1值用作特征值。In the case of FIG. 7 , the feature value can be calculated by using two points on the front side and two points on the rear side of the peak point. Find the peak point in the signal after the second transformation to obtain two values (p1, p2) on the side before the peak point and two values (n1, n2) on the back side of the peak point, where the value of p1 can be used as a feature value.

图8为示出将在特定振幅区间内外的点的标准偏差用作特征值的方法的图表,该方法利用位于预先设定的振幅区间内外的点的标准偏差。如图8所示,由正常波形的情况和室颤(VT)的情况的比较可见,根据经过第二变换的信号的振幅的点分布不同。FIG. 8 is a graph showing a method of using the standard deviation of points inside and outside a specific amplitude interval as a feature value, which uses the standard deviation of points inside and outside a preset amplitude interval. As shown in FIG. 8, it can be seen from a comparison between the case of the normal waveform and the case of ventricular fibrillation (VT) that point distributions differ according to the amplitude of the second converted signal.

图9为示出利用经过第二变换的信号并将在预先设定的振幅区间内外的点之间的距离的平均值用作特征值的方法。例如,当预先设定振幅区间的一定范围时,可以计算在范围内的点的平均距离。上述范围可以为-50至50或-200至200。FIG. 9 is a diagram showing a method of using the second converted signal and using the average value of the distances between points inside and outside a preset amplitude interval as a feature value. For example, when a certain range of the amplitude interval is preset, the average distance of points within the range can be calculated. The above range may be -50 to 50 or -200 to 200.

图10为示出当将经过第二变换的信号的点连接成直线时的点和点之间的倾斜度的标准偏差被用作特征值的方法。虽然以往没有利用上述特征值,但在本发明中,将上述特征值用作加权模糊隶属度函数的输入值,从而能够缩短冲击信号检测时间并提高检测的准确度。FIG. 10 is a diagram illustrating a method in which points and standard deviations of inclinations between points are used as feature values when points of the second transformed signal are connected into a straight line. Although the above-mentioned feature values have not been used in the past, in the present invention, the above-mentioned feature values are used as input values of the weighted fuzzy membership function, so that the shock signal detection time can be shortened and the detection accuracy can be improved.

上述示意性特征值被用作基于加权模糊隶属度函数的神经网络的输入特征,以在加权模糊隶属度函数输出关于是否冲击信号的判断结果。基于加权模糊隶属度函数的神经网络(Neural Network with Weighted Fuzzy Membership Function,NEWFM)是通过利用从输入所学习的加权模糊隶属度函数的境界值来分类的监督式学习模糊神经网络。The above schematic eigenvalues are used as the input features of the neural network based on the weighted fuzzy membership function, so that the weighted fuzzy membership function can output a judgment result on whether the signal is impacted. Neural Network with Weighted Fuzzy Membership Function (NEWFM) is a supervised learning fuzzy neural network for classification by utilizing the boundary value of the weighted fuzzy membership function learned from the input.

NEWFM的结构由输入(input)、超盒(hyper-box)、类(class)的三个阶层构成。输入阶层由n个输入节点构成,且一个特征值被输入到各输入节点。超盒阶层由m个超盒节点构成,第一个超盒节点B1与一个类节点连接,且具有n个模糊集合。The structure of NEWFM consists of three levels: input, hyper-box, and class. The input layer is composed of n input nodes, and one feature value is input to each input node. The superbox hierarchy is composed of m hyperbox nodes, the first hyperbox node B1 is connected with a class node, and has n fuzzy sets.

通过上述方法,缩短判断是否冲击信号所需的时间,以在需要除颤的环境下迅速施加除颤,从而能够提高患者的生存率。Through the above method, the time required for judging whether to shock the signal is shortened, so that defibrillation can be quickly applied in the environment where defibrillation is required, thereby improving the survival rate of patients.

另外,上述冲击信号检测方法通过计算机可读代码/指令/程序实施。例如,所述方法可通过使用计算机可读记录介质在操作上述代码/指令/程序的通用数字计算机上实施。上述计算机可读记录介质的实例包括磁性存储介质(如,光盘、软盘、硬盘、磁带等)、光学可读介质(如CD-ROM或DVD)以及载波(例如,通过互联网的传输)形态等存储介质。并且,本发明的实施例可以由内装有计算机可读的编码的(多个)媒体实现,使得由网络连接的多个计算机系统以分散方式处理并操作。而且,由本发明的方法实现的功能程序、编码、编码段由属于本发明的技术领域的程序设计员可容易推论。In addition, the above shock signal detection method is implemented by computer readable codes/instructions/programs. For example, the method can be implemented on a general-purpose digital computer operating the above-mentioned codes/instructions/programs by using a computer-readable recording medium. Examples of the above-mentioned computer-readable recording medium include magnetic storage media (such as optical disks, floppy disks, hard disks, magnetic tapes, etc.), optically readable media (such as CD-ROM or DVD), and storage media such as carrier wave (such as transmission through the Internet) forms. medium. Also, the embodiments of the present invention can be implemented by medium(s) embedding computer-readable code such that a plurality of computer systems connected by a network process and operate in a distributed manner. Furthermore, the functional programs, codes, and code segments realized by the method of the present invention can be easily deduced by programmers belonging to the technical field of the present invention.

上述描述仅涉及本发明的技术精神的一具体实施例的描述,而且本发明所属领域的技术人员不得脱离本发明的基本特征来进行不同的修改或改变。因此,本发明所披露的实施例不是为了限制本发明的技术精神,而是为了描述该技术精神,而且本发明的范围不应限于所述实施例。本发明的保护范围应该通过权利要求所确定,以及在等效范围内所有技术精神的解释均应该落入于本发明的范围之内。The above description only relates to the description of a specific embodiment of the technical spirit of the present invention, and those skilled in the art of the present invention shall not deviate from the basic features of the present invention to make various modifications or changes. Therefore, the embodiments disclosed in the present invention are not intended to limit the technical spirit of the present invention but to describe the technical spirit, and the scope of the present invention should not be limited to the embodiments. The protection scope of the present invention should be determined by the claims, and all interpretations of the technical spirit within the equivalent scope should fall within the scope of the present invention.

Claims (13)

1. the impact signal detection method of a kind of heart defibrillator, it is characterised in that comprise the following steps:
Receive electrocardiosignal;
First conversion is carried out to the electrocardiosignal of the receiving;
Second is carried out to the electrocardiosignal by the described first conversion to convert;
Utilize the signal of change characteristic value by the second conversion;And
The characteristic value of the calculating is used as input value and impact signal is detected by Weighted Fuzzy membership function.
2. the impact signal detection method of heart defibrillator according to claim 1, it is characterised in that the receiving Signal is digital form signal.
3. the impact signal detection method of heart defibrillator according to claim 1, it is characterised in that described first becomes It is changed to wavelet transformation.
4. the impact signal detection method of heart defibrillator according to claim 1, it is characterised in that described second becomes It is changed to delay conversion.
5. the impact signal detection method of heart defibrillator according to claim 4, it is characterised in that the delay becomes Change and realized by formula " Y (x)=X (x+0.5)-X (x) ", in formula, the X (x) is the signal by the first conversion, and Y (x) is warp Cross the signal of the second conversion.
6. the impact signal detection method of heart defibrillator according to claim 1, it is characterised in that also include:
Judge whether asystolic step by using the signal by the second conversion.
7. the impact signal detection method of heart defibrillator according to claim 6, it is characterised in that the judgement is No asystolic step includes being judged by using the summation of the absolute value of the signal value by the second conversion The step of.
8. the impact signal detection method of heart defibrillator according to claim 6, it is characterised in that the judgement is No asystolic step is included by using the step judged by the distance between signal value of the second conversion Suddenly.
9. the impact signal detection method of heart defibrillator according to claim 6, it is characterised in that if it is determined that being The no asystolic judged result is no, the step of just carrying out the calculating characteristic value.
10. the impact signal detection method of heart defibrillator according to claim 1, it is characterised in that the calculating The step of characteristic value including calculate it is described by second conversion signal value in amplitude set in advance interval in value it Between average distance the step of.
11. the impact signal detection method of heart defibrillator according to claim 1, it is characterised in that the calculating The step of characteristic value, connects the step of the standard deviation of the gradient of the straight line of the signal value by the second conversion including calculating Suddenly.
12. the impact signal detection method of heart defibrillator according to claim 1, it is characterised in that the calculating The step of characteristic value including calculate the number of peak value of the signal by the second conversion, the front and rear value of peak value, be contained in it is pre- The step of at least one in the standard deviation of the peak value of the scope first set.
13. the impact signal detection method of heart defibrillator according to claim 1, it is characterised in that the calculating Characteristic value be seven.
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