CN107014877B

CN107014877B - Dynamic continuous blood glucose monitoring system

Info

Publication number: CN107014877B
Application number: CN201710395721.0A
Authority: CN
Inventors: 白戈; 易晓兵; 朱昊轩
Original assignee: Beijing Eazy Tek Bio Technology Co ltd
Current assignee: Beijing Eazy Tek Bio Technology Co ltd
Priority date: 2017-05-27
Filing date: 2017-05-27
Publication date: 2023-06-20
Anticipated expiration: 2037-05-27
Also published as: CN107014877A

Abstract

The invention discloses a dynamic continuous blood glucose monitoring system, which comprises a skin treatment system and a blood glucose monitoring system. The skin treatment system comprises a skin grinding permeation promotion processor, and comprises a handle body, wherein the front end of the handle body is provided with a front end treatment assembly, a processor circuit assembly, a power supply device and a motor are arranged in the handle body, and an output shaft of the motor is connected with the front end treatment assembly. The blood glucose monitoring system includes a single use accessory and a monitor. The disposable accessories comprise a disposable sensor, a disposable transmitter, a disposable positioning patch, a disposable hydration liquid and a disposable hydration box. The treatment head for treating the skin in the skin treatment system and the use accessory in the blood sugar monitoring system are disposable, so that the skin treatment system is convenient and sanitary, has small product specification and is convenient to carry. The monitoring does not need to collect blood frequently, and pain and wound infection during repeated blood collection are avoided. The monitoring data is transmitted to the monitor in real time in a wireless mode, so that the blood sugar concentration level of the patient can be more systematically known.

Description

Dynamic continuous blood glucose monitoring system

Technical Field

The invention relates to a dynamic continuous blood glucose monitoring system.

Background

Diabetes is a metabolic syndrome mainly characterized by chronic hyperglycemia, and is accompanied by metabolic disorders such as fat, protein, water, and electrolytes, and also by chronic damage to various organs due to glucose metabolism disorder caused by insulin deficiency or insulin bioavailablity disorder.

At present, a method for thoroughly and radically treating diabetes is not found at present due to the limitation of the modern medical development level. The blood glucose level of diabetics always does not fluctuate significantly regularly between hyperglycemia and hypoglycemia. Diabetes control and complications experimental reports show that the dosage of the hypoglycemic drugs and the insulin is regulated by frequently detecting the blood sugar concentration, so that complications caused by diabetes can be effectively reduced by strictly controlling the blood sugar concentration. However, the simplest blood glucose test method is to take a blood sample from the fingertip of a subject, and the blood glucose self-test method greatly improves the nursing level of a diabetic patient, but has the defects of complex operation; for example, when blood is sampled and detected, the finger tips with dense nerves must be punctured, so that pain is caused to a patient; for example, the wound is at risk of being infected by other diseases, so that psychological stress is caused to the patient, and frequent detection of blood sugar is not facilitated; such as higher cost of detection. At the same time, the detection of discrete time points with low frequency may miss some situations where blood glucose is higher or lower than normal, thus being disadvantageous for the care of diabetes. Especially when the patient is diagnosed with diabetes, the blood glucose parameters need to be continuously monitored for a long time to prevent various complications, the existing blood glucose monitor can only realize batch detection of blood glucose, and can not realize continuous dynamic monitoring of blood glucose data of the diabetes so as to enable monitoring staff to remotely track the blood glucose concentration level of the diabetes, so that the daily detection of a user and the monitoring of the monitoring staff are very inconvenient. Therefore, there is an urgent need to develop new test instruments to accommodate the need for the frequency of testing by diabetics.

Disclosure of Invention

The invention aims to provide a dynamic continuous blood glucose monitoring system.

The technical scheme for realizing the purpose of the invention is as follows: a dynamic continuous blood glucose monitoring system includes a skin treatment system and a blood glucose monitoring system.

The skin treatment system includes a skin abrasion penetration enhancing processor; the skin grinding permeation promotion processor comprises a handle body with a hollow structure, wherein the front end of the handle body is provided with a front end treatment assembly; the inner cavity of the handle body is provided with a processor circuit component, a power supply device and a motor, and an output shaft of the motor is connected with a front end processing component at the front end of the handle body.

The blood glucose monitoring system includes a single use accessory and a monitor; the disposable accessories comprise a disposable sensor, a disposable transmitter, a disposable positioning patch, a disposable hydration liquid and a disposable hydration box.

The disposable sensor comprises a sensor shell, a printed circuit board arranged on the sensor shell and a hydrogel disc arranged on the printed circuit board; the printed circuit board is provided with a sensor body and conductive metal connected with the sensor body; the hydrogel disk is arranged on the upper end face of the sensor body.

The disposable transmitter comprises an upper shell, a transmitter circuit board and a lower shell; the transmitter circuit board is arranged in a cavity formed by the upper shell and the lower shell; the transmitter circuit board is provided with a main control chip, a power supply device for providing power for the main control chip, a wireless communication module connected with the main control chip and used for transmitting data to the monitor, a conductive spring piece connected with the main control chip and used for connecting the disposable sensor, and a trigger switch triggered by the disposable sensor so as to control the on-off of a circuit in the transmitter circuit board; when the disposable transmitter and the disposable sensor are connected in a matched mode, a sensor shell of the disposable sensor is connected with an upper shell of the disposable transmitter in a matched mode, and conductive metal on a printed circuit board in the disposable sensor is contacted with a conductive spring sheet on the circuit board of the transmitter in the disposable transmitter.

The disposable positioning patch comprises a positioning patch, a positioning shell arranged on the upper end surface of the positioning patch and centrifugal paper arranged on the lower end surface of the positioning patch; the lower end face of the positioning paste is provided with adhesive; the positioning shell is of a box-shaped structure with an open upper end.

The single-use hydration fluid is used to activate the hydrogel pads on the printed circuit board in the single-use sensor.

The disposable hydration box is internally provided with a hydration tank matched with the sensor shell of the disposable sensor.

The processor circuit component comprises a circuit board, a main control module arranged on the circuit board, a skin impedance acquisition module and a motor driving module, wherein the skin impedance acquisition module and the motor driving module are electrically connected with the main control module; the motor driving module receives a control signal of the main control module through the motor driving chip so as to control the rotation of the motor.

The front end of the handle body is provided with a mounting port communicated with the inner cavity of the handle body, and the mounting port is provided with a front end processing assembly; the front end processing assembly comprises a head cover detachably connected to the handle body outside the mounting port, a top end cover sleeved on the head cover and a disposable processing head.

The head cover is of a cover body structure with an opening at the rear end, which is made of conductive materials, and the front end face of the head cover is provided with a cover body through hole which penetrates up and down, and the head cover is detachably connected to the mounting opening of the handle body through the opening at the rear end; the head cover is connected with the processor circuit component through a power supply wire arranged inside.

The top end cover comprises a connecting cover at the bottom end and a hollow contact end arranged on the front end surface of the connecting cover; the rear end of the connecting cover is clamped at the front end of the head cover; the front end face and the outer surface of the top end cover are provided with conductive coatings at the parts matched and connected with the head cover; the connecting cover in the contact end is provided with a connecting cover through hole.

The disposable treatment head is a cylinder body with an opening at the rear end and made of conductive materials, and the front end surface of the cylinder body is provided with a convex grinding strip.

The head cover is matched with the top end cover and then connected to the mounting opening of the handle body, and an output shaft of the motor sequentially penetrates through the cover body through hole and the connecting cover through hole and then protrudes out of the front end surface of the connecting cover; the disposable treatment sleeve is sleeved at the outer end of the motor output shaft, and the motor output shaft is electrically connected with the skin impedance acquisition module of the processor circuit assembly through a feedback wire arranged inside.

The sensor shell is of a box-shaped structure with an opening at the lower end and comprises a sensor top plate and a sensor coaming arranged at the periphery of the lower end surface of the sensor top plate; a sensor boss protruding upwards is arranged on the upper end surface of the sensor top plate, and a mounting groove recessed downwards is arranged in the middle of the sensor boss; the sensor coaming is provided with a fixing notch; a switch trigger block protruding downwards is arranged on the lower end surface of the sensor top plate; the outer side part of the sensor boss on the sensor top plate is provided with a plurality of air holes which penetrate through the mounting groove from outside to inside.

The printed circuit board is of a bendable plate structure, and is provided with a sensor body and conductive metal connected with the sensor body. The sensor body on the printed circuit board is arranged in the mounting groove of the sensor boss, the printed circuit board is bent and fixed on the sensor top plate through the fixing notch, and the conductive metal is connected with the sensor body and then extends to the other end of the printed circuit board.

The hydrogel disc is arranged on the upper end face of the sensor body of the printed circuit board, and glucose oxidase is arranged in the hydrogel disc.

The outer side of the sensor boss, which is close to the fixing notch, of the mounting groove of the sensor shell is provided with a connecting groove which is sunken downwards; a mounting hole penetrating up and down is arranged at the center of the mounting groove on the sensor top plate; the connection part of the sensor top plate and the sensor coaming of the sensor shell is provided with a plurality of mounting clamping holes which penetrate through the sensor top plate and the sensor coaming at the same time.

The printed circuit board comprises a sensing part, a fixing part and a connecting part for connecting the sensing part and the fixing part, and the sensing part, the fixing part and the connecting part are of an integrated structure; the sensing part is a circular plate which is matched and connected with the notch of the mounting groove on the upper end surface of the sensor shell; the fixing part is a U-shaped plate bent to form a U-shaped structure and comprises side plates arranged in parallel and bent plates connected with the side plates at two sides; the connecting part is a bending plate bent at an obtuse angle, the outer end of the upper part of the connecting part is connected with the sensing part, and the outer end of the lower part of the connecting part is connected with the upper side plate of the fixing part; the upper part of the connecting part and the sensing part are on the same plane; the side plate of the fixing part is arranged on a lower plane parallel to the sensing part; the sensor body is arranged on the sensing part; the conductive metal is connected with the sensor body and then sequentially extends to the connecting part and the fixing part.

When printed circuit board and sensor shell cooperation are connected, the lower terminal surface of sensor lower extreme is fixed in the mounting groove, and the upper portion of connecting portion sets up in the spread groove, and the fixed part is outside-in joint on the sensor roof of sensor shell through its U type structure by fixed breach department, sensor roof joint between both sides curb plate.

In the disposable transmitter, the upper shell is of a box-shaped structure with an opening at the lower end and comprises an upper shell top plate and an upper shell coaming arranged on the outer periphery of the lower end surface of the upper shell top plate; an upper shell boss protruding upwards is arranged on the upper shell top plate; the upper shell top plate at one side of the upper shell boss is provided with a downward concave fixing groove, and the bottom of the fixing groove is provided with a through hole penetrating up and down; the upper shell top plate is provided with a switch through hole penetrating up and down.

The transmitter circuit board is provided with a main control chip, a power supply device for supplying power to the main control chip, a wireless communication module connected with the main control chip and used for transmitting data, a conductive spring piece connected with the main control chip and used for connecting external hardware, and a trigger switch for controlling the on-off of the whole circuit.

The lower shell comprises a lower shell bottom plate and a lower shell coaming arranged on the upper end face of the lower shell bottom plate, and the peripheral outer edge of the lower shell bottom plate protrudes out of the lower shell coaming.

When the upper shell, the transmitter circuit board and the lower shell are connected in a matched mode, the transmitter circuit board is arranged on a lower shell bottom plate on the inner side of the lower shell coaming, and the conducting spring piece on the transmitter circuit board penetrates through the conducting hole in the fixed groove and protrudes out of the inner bottom surface of the fixed groove.

In the disposable transmitter, a sensor through hole penetrating up and down is arranged in the middle of an upper shell boss of an upper shell top plate; the transmitter circuit board is provided with a temperature sensor which is connected with the main control chip and used for detecting temperature, and the temperature sensor is arranged at the upper end of the power supply device; when the upper shell, the transmitter circuit board and the lower shell are matched and installed, the temperature sensor protrudes from bottom to top through the sensor through hole on the upper end face of the upper shell top plate.

When the disposable sensor and the disposable transmitter are connected in a matched mode, the temperature sensor of the transmitter circuit board sequentially penetrates through the sensor through hole and the installation Kong Dizhu on the sensor top plate from bottom to top, and the lower end of the sensing part of the printed circuit board in the installation groove is arranged.

In the disposable transmitter, a plurality of mounting clamping blocks protruding outwards are arranged on the outer side of an upper shell coaming of an upper shell, and the mounting clamping blocks are of slope structures with small upper ends and large lower ends; the lower casing coaming is provided with a plurality of mounting openings extending downwards from the upper end.

When the upper shell and the lower shell of the disposable transmitter are connected in a matched mode, the lower end of the installation clamping block on the upper shell coaming is clamped into the installation opening on the lower shell coaming from top to bottom.

The positioning shell is of a box-shaped structure with an opening at the upper end and comprises a positioning shell bottom plate and a positioning shell coaming arranged on the outer periphery of the upper end surface of the positioning shell bottom plate; a positioning through hole penetrating up and down is arranged in the middle of the positioning shell bottom plate; the positioning paste is provided with an opening which is consistent with the positioning through hole on the bottom plate of the positioning shell in size.

A plurality of convex positioning blocks are arranged on the outer side face of the sensor coaming of the sensor shell. The positioning block is of a slope structure with a small upper end and a large lower end.

The inner side of the positioning shell coaming is provided with a plurality of inwards concave positioning clamping grooves which are of a downhill structure with gradually increased grooving depth from top to bottom.

The skin treatment system further comprises a skin treatment device; the skin treater charging device comprises a charging device upper cover, a charging device shell, a charging device circuit board assembly arranged in an inner cavity formed by the charging device upper cover and the charging device shell, and a power interface arranged on the outer side of the charging device shell.

The charging device upper cover comprises an upper cover plate and an upper cover coaming arranged on the outer edge of the lower end face of the upper cover plate, a charging port is arranged in the middle of the upper end face of the upper cover plate, an inserting inner cylinder is formed in an opening of the charging port along the downward extension, and the lower end of the inserting inner cylinder is flush with the lower end of the upper cover coaming.

The charging device shell comprises a shell bottom plate and a shell coaming arranged on the outer edge of the upper end surface of the shell bottom plate, a cylinder with a hollow structure is arranged in the middle of the upper end surface of the shell bottom plate, a charging hole extending from top to bottom is arranged on the upper end surface of the cylinder, and when the charging device upper cover is in fit connection with the charging device shell, the lower end of the inserting inner cylinder is in fit connection with the cylinder; the outer side surface of the column body is wound with a plurality of transmitting coils electrically connected with the circuit board assembly of the charging device.

An induction coil which is induced by the magnetic field of the transmitting coil in the skin processor charging device is arranged on the inner side of the handle body; the induction coil generates current through magnetic field induction to supply power to the processor circuit assembly or store the current to the power supply device.

By adopting the technical scheme, the invention has the following beneficial effects: the invention comprises a skin treatment system and a blood sugar monitoring system, wherein a treatment head for treating skin in the skin treatment system and a use accessory in the blood sugar monitoring system are disposable, so that the invention is convenient and sanitary, has small product specification and is convenient to carry; the monitoring does not need to take blood frequently, so that pain and wound infection during repeated blood taking are avoided; the monitoring data is transmitted to the monitor in real time in a wireless mode, so that the blood sugar concentration level of the patient can be more systematically known.

Drawings

In order that the invention may be more readily understood, a more particular description of the invention will be rendered by reference to specific embodiments thereof which are illustrated in the appended drawings, in which

FIG. 1 is a schematic diagram of the continuous monitoring of analytes of the present invention.

Fig. 2 is a schematic diagram showing the overall structure of the skin abrasion permeation enhancer of fig. 1.

Fig. 3 is a schematic diagram of the explosive structure of fig. 2.

Fig. 4 is a schematic view of the handle body in fig. 2.

FIG. 5 is a schematic view of the nose cap of FIG. 2.

Fig. 6 is a schematic view of the top end cap of fig. 2.

Fig. 7 is a schematic view of the disposable processing head of fig. 2.

Fig. 8 is a circuit block diagram of fig. 2.

Fig. 9 is a schematic diagram of the overall structure of the single-use sensor in fig. 1.

Fig. 10 is an exploded view of the single-use sensor of fig. 1.

Fig. 11 is a schematic view of the upper end surface of the sensor housing of fig. 10.

Fig. 12 is a schematic view of the lower end surface of the sensor housing of fig. 10.

Fig. 13 is a schematic view of the printed circuit board structure of fig. 10.

Fig. 14 is a schematic view of the overall structure of the single-use transmitter of fig. 1.

Fig. 15 is a schematic view of the explosive structure of the single-use transmitter of fig. 1.

Fig. 16 is a schematic view of the upper end surface of the upper housing of fig. 15.

Fig. 17 is a schematic view of the lower end of the upper housing of fig. 15.

Fig. 18 is a schematic diagram of the transmitter circuit board structure of fig. 15.

Fig. 19 is a circuit block diagram of fig. 18.

Fig. 20 is a schematic view of the lower housing in fig. 15.

Fig. 21 is a schematic view of the overall structure of the single-use positioning patch in fig. 1.

Fig. 22 is a schematic view of the explosion structure of the single-use positioning patch in fig. 1.

Fig. 23 is a schematic view of the positioning shell in fig. 22.

Fig. 24 is a schematic view showing the overall structure of the skin treater charging device.

Fig. 25 is an exploded view of the skin treater charging device.

Fig. 26 is a schematic view of the upper cover of the charging device in fig. 25.

Fig. 27 is a front view of fig. 26.

Fig. 28 is a top view of fig. 26.

Fig. 29 is a schematic view of a charging device housing in fig. 25.

Detailed Description

Example 1

Fig. 1 shows a dynamic continuous blood glucose monitoring system according to this embodiment, including a skin treatment system and a blood glucose monitoring system. The skin treatment system comprises a skin abrasion penetration enhancer 1 and a skin treater charging device 8. The blood glucose monitoring system includes a single use accessory and a monitor 2. The disposable accessories comprise a disposable sensor 3, a disposable transmitter 4, a disposable positioning patch 5, a disposable hydration liquid 6 and a disposable hydration box 7.

As shown in fig. 2 and 3, the skin abrasion and permeation promotion processor 1 comprises a handle body 1-1 with a hollow structure, and a front end processing assembly 1-2 is arranged at the front end of the handle body 1-1. The inner cavity of the handle body 1-1 is provided with a processor circuit component 1-3, a power supply device 1-4 and a motor 1-5, and an output shaft of the motor 1-5 is connected with a front end processing component 1-2 at the front end of the handle body 1-1. As shown in fig. 8, the processor circuit assembly 1-3 includes a circuit board 1-3-1, a main control module 1-3-2 disposed on the circuit board 1-3-1, a skin impedance acquisition module 1-3-3 electrically connected to the main control module 1-3-2, and a motor driving module 1-3-4. The motor driving module 1-3-2 receives a control signal of the main control module 1-3-2 through the motor driving chip so as to control the rotation of the motor 1-5. The front end of the handle body 1-1 is provided with a mounting port 1-1-1 communicated with the inner cavity of the handle body 1-1, and the front end processing assembly 1-2 is arranged at the mounting port 1-1-1. The front end processing component 1-2 comprises a head cover 1-2-1 detachably connected to the handle body 1-1 outside the mounting port 1-1-1, a top end cover 1-2-2 sleeved on the head cover 1-2-1 and a disposable processing head 1-2-3.

As shown in FIG. 5, the nose cap 1-2-1 is a rear-end-opening cap structure made of conductive materials, the front end face is provided with a cap through hole 1-2-1-1 penetrating up and down, and the nose cap 1-2-1 is detachably connected to the mounting port 1-1-1 of the handle body 1-1 through the rear-end opening. The head cap 1-2-1 is connected to the processor circuit assembly 1-3 by internally disposed power conductors. As shown in fig. 6, the top cap 1-2-2 includes a connection cap 1-2-2-1 at the bottom end and a hollow contact terminal 1-2-2-2 provided on the front end surface of the connection cap 1-2-2-1. The rear end of the connecting cover 1-2-2-1 is clamped at the front end of the head cover 1-2-1. The front end face and the outer surface of the top end cover 1-2-2 and the part matched and connected with the head cover 1-2-1 are provided with conductive coatings. The connecting cover in the contact end 1-2-2-2 is provided with a connecting cover through hole 1-2-2-3. As shown in FIG. 7, the disposable processing head 1-2-3 is a cylinder body with an opening at the rear end and made of conductive materials, and the front end surface of the cylinder body is provided with a convex grinding strip 1-2-3-1. The head cover 1-2-1 is matched with the top end cover 1-2-2 and then connected to the mounting opening 1-1-1 of the handle body 1-1, and the output shaft 1-5-1 of the motor 1-5 sequentially penetrates through the cover body through hole 1-2-1-1 and the connecting cover through hole 1-2-2-3 and then protrudes out of the front end face of the connecting cover 1-2-2-1. The disposable treatment head 1-2-3 is sleeved at the outer end of the output shaft 1-5-1 of the motor 1-5, and the output shaft 1-5-1 of the motor 1-5 is electrically connected with the skin impedance acquisition module 1-3-3 of the processor circuit assembly 1-3 through a feedback wire arranged inside.

The skin grinding penetration promoting processor 1 applies a tiny current signal to the skin to be measured by means of a head cap 1-2-1 connected with a processor circuit assembly 1-3 through a power supply wire, and simultaneously detects a voltage signal on the surface of a tissue by means of a disposable processing head 1-2-3 on an output shaft 1-5-1 of a motor 1-5 connected with the processor circuit assembly 1-3 through a feedback wire arranged inside, and calculates the corresponding electrical impedance and the change thereof from the detected signal. The skin abrasion and permeation enhancer 1 grinds the skin of the area to be measured of the patient, the skin abrasion and permeation enhancer 1 determines the skin permeability level based on the conductivity using a suitable algorithm, and once the desired permeability level is reached, the skin abrasion and permeation enhancer 1 is removed for the next operation. After the skin treatment, the disposable treatment heads 1-2-3 on the skin grinding and permeation enhancer 1 are removed and discarded according to the standard procedure for medical waste treatment in hospitals. The skin abrasion penetration enhancing processor 1 is thoroughly cleaned and disinfected using a chlorine-containing disinfectant.

As shown in fig. 24, the skin treater charging device 8 includes a charging device upper cover 8-1, a charging device housing 8-2, a charging device circuit board assembly 8-3 provided in an inner cavity formed by the charging device upper cover 8-1 and the charging device housing 8-2, and a power supply interface 8-4 provided on an outer side of the charging device housing 8-2.

As shown in fig. 25 to 29, the upper cover 8-1 of the charging device comprises an upper cover plate 8-1-1 and an upper cover coaming plate 8-1-2 arranged on the outer edge of the lower end face of the upper cover plate 8-1, a charging port 8-1-2 is arranged in the middle of the upper end face of the upper cover plate 8-1, an opening of the charging port 8-1-2 extends downwards to form an inserting inner cylinder 8-1-3, and the lower end of the inserting inner cylinder 8-1-3 is flush with the lower end of the upper cover coaming plate 8-1-2. The charging device shell 8-2 comprises a shell bottom plate 8-2-1 and a shell coaming plate 8-2-2 arranged on the outer edge of the upper end face of the shell bottom plate 8-2-1, a cylinder 8-2-3 with a hollow structure is arranged in the middle of the upper end face of the shell bottom plate 8-2-1, a charging hole 8-2-4 extending from top to bottom is arranged on the upper end face of the cylinder 8-2-3, and when the charging device upper cover 8-1 is in fit connection with the charging device shell 8-2, the lower end of the inserting inner cylinder 8-1-3 is in fit connection with the cylinder 8-2-3. The outer side surface of the column body 8-2-3 is wound with a plurality of transmitting coils 8-5 electrically connected with the charging device circuit board assembly 8-3. An induction coil 1-6 which is used for inducing the magnetic field of a transmitting coil 8-5 in a charging device 8 of the skin processor is arranged on the inner side of the handle body 1-1. The induction coil 1-6 generates a current by magnetic field induction to supply power to the processor circuit assembly 1-3 or store to the power supply device 1-4.

After the skin grinding and permeation promotion processor 1 is used up and cleaned and disinfected, the skin grinding and permeation promotion processor 1 is placed in the charging port 8-1-2 of the skin processor charging device 8 for next use.

The blood glucose monitoring system includes a single use accessory and a monitor 2. The disposable accessories comprise a disposable sensor 3, a disposable transmitter 4, a disposable positioning patch 5, a disposable hydration liquid 6 and a disposable hydration box 7.

As shown in fig. 9 and 10, the single-use sensor 3 includes a sensor housing 3-1, a printed circuit board 3-2 provided on the sensor housing 3-1, and a hydrogel disk 3-3 provided on the printed circuit board 3-2. The printed circuit board 3-2 is provided with a sensor body 3-2-1 and a conductive metal 3-2-2 connected with the sensor body 3-2-1. The hydrogel disk 3-3 is disposed on the upper end face of the sensor body 3-2-1.

As shown in fig. 11 and 12, the sensor housing 3-1 has a box-like structure with an open lower end, and includes a sensor top plate 3-1-1 and a sensor cover plate 3-1-2 provided on the outer periphery of the lower end surface of the sensor top plate 3-1-1. The upper end face of the sensor top plate 3-1-1 is provided with an upward protruding sensor boss 3-1-3, and the middle position of the sensor boss 3-1-3 is provided with a downward recessed mounting groove 3-1-4. The sensor coaming 3-1-2 is provided with a fixing notch 3-1-5. The lower end face of the sensor top plate 3-1-1 is provided with a switch trigger block 3-1-6 protruding downwards. The outer side part of the sensor boss 3-1-3 on the sensor top plate 3-1-1 is provided with a plurality of ventilation holes 3-1-3-1 penetrating into the mounting groove 3-1-4 from outside to inside. The mounting groove 3-1-4 of the sensor shell 3-1 is provided with a connecting groove 3-1-7 which is concave downwards by the outer side sensor boss 3-1-3 of the fixing notch 3-1-5. The center of the mounting groove 3-1-4 on the sensor top plate 3-1-1 is provided with a mounting hole 3-1-8 penetrating up and down. In the disposable sensor 3, a plurality of mounting clamping holes 3-1-9 which penetrate through the sensor top plate 3-1-1 and the sensor coaming 3-1-2 at the same time are arranged at the connecting part of the sensor top plate 3-1-1 and the sensor coaming 3-1-2 of the sensor shell 3-1.

As shown in fig. 13, the printed circuit board 3-2 has a bendable plate structure, and the printed circuit board 3-2 is provided with a sensor body 3-2-1 and a conductive metal 3-2-2 connected to the sensor body 3-2-1. The sensor body 3-2-1 on the printed circuit board 3-2 is arranged in the mounting groove 3-1-4 of the sensor boss 3-1-3, the printed circuit board 3-2 is bent and fixed on the sensor top plate 3-1-1 through the fixing notch 3-1-5, and the conductive metal 3-2-2 extends to the other end of the printed circuit board 3-2 after being connected with the sensor body 3-2-1. The printed circuit board 3-2 comprises a sensing part 3-2-3, a fixing part 3-2-4 and a connecting part 3-2-5 for connecting the sensing part 3-2-3 and the fixing part 3-2-4, wherein the sensing part 3-2-3, the fixing part 3-2-4 and the connecting part 3-2-5 are of an integrated structure. The sensing part 3-2-3 is a circular plate which is matched and connected with a notch of the mounting groove 3-3-4 on the upper end surface of the sensor shell 3-1. The fixing part 3-2-4 is a U-shaped plate which is bent to be in a U-shaped structure and comprises side plates 3-2-4-1 which are arranged in parallel and a bending plate 3-2-4-2 which is connected with the side plates 3-2-4-1 at two sides. The connecting part 3-2-5 is a bending plate bent at an obtuse angle, the outer end of the upper part of the connecting part 3-2-5 is connected with the sensing part 3-2-3, and the outer end of the lower part of the connecting part 3-2-5 is connected with the upper side plate 3-2-4-1 of the fixing part 3-2-4. The upper part of the connecting part 3-2-5 is on the same plane with the sensing part 3-2-3. The side plate 3-2-4-1 of the fixing portion 3-2-4 is on a lower plane parallel to the sensing portion 3-2-3. The sensor body 3-2-1 is provided on the sensor portion 3-2-3. The conductive metal 3-2-2 is connected to the sensor body 3-2-1 and then sequentially extends to the connecting portion 3-2-5 and the fixing portion 3-2-4.

The hydrogel disk 3-3 is arranged on the upper end face of the sensor body 3-2-1 of the printed circuit board 3-2, and glucose oxidase is arranged in the hydrogel disk 3-3.

When the printed circuit board 3-2 is connected with the sensor shell 3-1 in a matched manner, the lower end face of the sensing part 3-2-3 is fixed in the mounting groove 3-1-4, the upper part of the connecting part 3-2-5 is arranged in the connecting groove 3-1-7, the fixing part 3-2-4 is clamped on the sensor top plate 3-1-1 of the sensor shell 3-1 from outside to inside through the U-shaped structure of the fixing notch 3-1-5, and the sensor top plate 3-1-1 is clamped between the side plates 3-2-4-1 at two sides.

As shown in fig. 14 and 15, the single-use transmitter 4 includes an upper case 4-1, a transmitter circuit board 4-2, and a lower case 4-3. The transmitter circuit board 4-2 is disposed in a cavity formed by the upper case 4-1 and the lower case 4-3.

As shown in fig. 16 and 17, the upper case 4-1 has a box-like structure with an open lower end, and includes an upper case top plate 4-1-1 and an upper case surrounding plate 4-1-2 provided circumferentially outside the lower end face of the upper case top plate 4-1-1. The upper shell top plate 4-1-1 is provided with an upper shell boss 4-1-3 protruding upwards. The upper shell top plate 4-1-1 on one side of the upper shell boss 4-1-3 is provided with a downward concave fixing groove 4-1-4, and the bottom of the fixing groove 4-1-4 is provided with a through hole 4-1-5 penetrating up and down. The upper shell top plate 4-1-1 is provided with a switch through hole 4-1-6 which penetrates up and down. The middle position of the upper shell boss 4-1-3 of the upper shell top plate 4-1-1 is provided with a sensor through hole 4-1-7 which penetrates up and down. In the disposable transmitter 4, a plurality of mounting clamping blocks 4-1-8 protruding outwards are arranged on the outer side of an upper shell coaming 4-1-2 of an upper shell 4-1, and the mounting clamping blocks 4-1-8 are of slope structures with small upper ends and large lower ends.

As shown in fig. 18 and 19, the transmitter circuit board 4-2 is provided with a main control chip 4-2-1, a power supply device 4-2-2 for supplying power to the main control chip 4-2-1, a wireless communication module 4-2-3 connected with the main control chip 4-2-1 for transmitting data to the monitor 2, a conductive spring piece 4-2-4 connected with the main control chip 4-2-1 for connecting the disposable sensor 3, and a trigger switch 4-2-5 triggered by the disposable sensor 3 to control the on-off of a circuit in the transmitter circuit board 4-2. The transmitter circuit board 4-2 is provided with a temperature sensor 4-2-6 which is connected with the main control chip 4-2-1 and used for detecting temperature, and the temperature sensor 4-2-6 is arranged at the upper end of the power supply device 4-2-2. When the upper shell 4-1, the transmitter circuit board 4-2 and the lower shell 4-3 are assembled in a matched mode, the temperature sensor 4-2-6 passes through the sensor through hole 4-1-7 from bottom to top and protrudes out of the upper end face of the upper shell top plate 4-1-1.

As shown in fig. 20, the lower case 4-3 includes a lower case bottom plate 4-3-1 and a lower case coaming 4-3-2 provided on an upper end face of the lower case bottom plate 4-3-1, and a circumferential outer edge of the lower case bottom plate 4-3-1 protrudes outside the lower case coaming 4-3-2. The lower casing coaming 4-3-2 is provided with a plurality of mounting ports 4-3-3 extending downwards from the upper end.

When the upper shell 4-1, the transmitter circuit board 4-2 and the lower shell 4-3 are connected in a matched mode, the transmitter circuit board 4-2 is arranged on the lower shell bottom plate 4-3-1 on the inner side of the lower shell coaming 4-3-2, and the conducting spring piece 4-2-4 on the transmitter circuit board 4-2 penetrates through the conducting hole 4-1-5 in the fixed groove 4-1-4 and protrudes out of the inner bottom surface of the fixed groove 4-1-4. The lower ends of the mounting clamping blocks 4-1-8 on the upper shell coaming 4-1-2 are clamped into the mounting openings 4-3-3 on the lower shell coaming 4-3-2 from top to bottom.

When the disposable transmitter 4 and the disposable sensor 3 are connected in a matched manner, the sensor shell 3-1 of the disposable sensor 3 is connected with the upper shell 4-1 of the disposable transmitter 4 in a matched manner, and the mounting clamping blocks 4-1-8 on the upper shell coaming 4-1-2 of the upper shell 4-1 of the disposable transmitter 4 are clamped into the mounting clamping holes 3-1-9 of the sensor shell 3-1 of the disposable sensor 3. The conductive metal 3-2-2 on the printed circuit board 3-2 in the disposable sensor 3 is in contact with the conductive dome 4-2-4 on the transmitter circuit board 4-2 in the disposable transmitter 4. The temperature sensor 4-2-6 of the transmitter circuit board 4-2 sequentially passes through the sensor through hole 4-1-7 and the mounting hole 3-1-8 on the sensor top plate 3-1 from bottom to top to prop against the lower end of the sensing part 3-2-3 of the printed circuit board 3-2 arranged in the mounting groove 3-1-4.

As shown in fig. 21 and 22, the single-use positioning patch 5 includes a positioning patch 5-1, a positioning case 5-2 provided on an upper end surface of the positioning patch 5-1, and a centrifugal paper 5-3 provided on a lower end surface of the positioning patch 5-1. The lower end face of the positioning paste 5-1 is provided with adhesive. The positioning shell 5-2 is a box-like structure with an open upper end.

As shown in fig. 23, the positioning shell 5-2 has a box-like structure with an open upper end, and comprises a positioning shell bottom plate 5-2-1 and a positioning shell coaming 5-2-2 arranged on the outer periphery of the upper end surface of the positioning shell bottom plate 5-2-1. The middle position of the positioning shell bottom plate 5-2-1 is provided with a positioning through hole 5-2-3 which penetrates up and down. The positioning paste 5-1 is provided with an opening which is consistent with the positioning through hole 5-2-3 on the positioning shell bottom plate 5-2-1 in size. The outer side surface of the sensor coaming 3-1-2 of the sensor shell 3-1 is provided with a plurality of convex positioning blocks 3-1-11. The positioning blocks 3-1-11 are slope structures with small upper ends and large lower ends. The inner side of the positioning shell coaming 5-2-2 is provided with a plurality of inwards concave positioning clamping grooves 5-2-4, and the positioning clamping grooves 5-2-4 are of a downhill structure with gradually increased grooving depth from top to bottom.

The single-use hydration liquid 6 is used to activate the hydrogel disc 3-3 on the printed circuit board 3-2 in the single-use sensor 3.

The disposable hydration box 7 is internally provided with a hydration tank matched with the sensor shell 3-1 of the disposable sensor 3.

In the case of the present invention in use,

(1) The skin of the area to be tested is wiped and disinfected by 75% alcohol, and the area to be tested is waited for five minutes until the alcohol is completely volatilized.

(2) And opening the disposable positioning patch 5 in the blood sugar monitoring system accessory for packaging, uncovering the centrifugal paper 5-4 of the disposable positioning patch 5, attaching the disposable positioning patch to the skin of the area to be tested treated by alcohol, and pressing the positioning patch 5-1 with fingers for four sides so as to be tightly attached to the arm.

(3) The package of the disposable treatment head 1-2-3 is disassembled, and the disposable treatment head 1-2-3 is lightly pushed into the top end cover 1-2-2 of the skin grinding permeation promotion processor 1. Ensure that the disposable treatment heads 1-2-3 do not fall off.

(4) The skin in the positioning through holes 5-2-3 of the disposable positioning patch 5 is rubbed by using a benzalkonium chloride tablet.

(5) The skin grinding permeation promotion processor 1 is vertically inserted into the positioning through holes 5-2-3 of the disposable positioning patch 5, and the disposable treatment head 1-2-3 is closely attached to the skin.

(6) The skin grinding and permeation promotion processor 1 is started by lightly pressing a start key, the stable pressure and the vertical direction of the skin grinding and permeation promotion processor 1 are maintained, and the skin grinding and permeation promotion processor 1 stops after the treatment is finished.

(7) The skin treatment is ended. The disposable heads 1-2-3 on the skin abrasion permeation enhancer processor 1 are removed and discarded according to standard procedures for hospital disposal of medical waste.

(8) The skin abrasion penetration enhancing processor 1 is thoroughly cleaned and disinfected using a chlorine-containing disinfectant. After cleaning and disinfection, the skin abrasion penetration enhancer 1 is placed in the skin treater charging means 8 for the next use.

(9) Opening the package of the disposable transmitter 4 and taking out the disposable transmitter 4; the package of the single-use sensor 3 is opened and the single-use sensor 3 is taken out. The disposable sensor 3 and the disposable transmitter 4 are correspondingly and well buckled into a whole.

(10) The package of the disposable hydration cassette 7 is opened and the disposable hydration cassette 7 is taken out. Taking out the disposable hydration liquid 6, opening the bottle mouth and dripping all the hydration liquid into the hydration tank of the disposable hydration box 7.

(11) The single-use sensor 3 and the single-use transmitter 4 which are fastened are placed in a hydration tank of the single-use hydration cartridge 7 with the single-use sensor 3 facing downwards, and hydration treatment is performed.

(12) The buckled disposable sensor 3 and the disposable transmitter 4 are taken out from the disposable hydration box 7 and are buckled in the positioning shell 5-2 of the disposable positioning patch 5 immediately, and then the blood sugar concentration in the body of the tested person can be monitored through the monitor 2.

After the skin of the person to be measured is treated, glucose in the skin of the treated part of the person to be measured is extracted and contacted with glucose oxidase of the hydrogel disc 3-3 of the disposable sensor 3. Glucose reacts with glucose oxidase to form hydrogen peroxide, which is transported to the surface of the sensor body 3-2-1 of the single-use sensor 3, and the sensor body 3-2-1 electrochemically oxidizes the hydrogen peroxide. The current generated in this oxidation reaction is indicative of the rate of hydrogen peroxide generation within the hydrogel disk 3-3, which is related to the flow of glucose through the skin of the treatment site, which is proportional to the concentration of glucose in the blood of the user, and this trend of change is transmitted to the monitor 2 via the wireless communication module 4-2-3 within the single-use transmitter 4, which can be detected and analyzed by one of ordinary skill in the art.

The foregoing embodiments have been provided for the purpose of illustrating the general principles of the present invention, and are more fully described herein with reference to the accompanying drawings, in which the principles of the present invention are shown and described, and in which the general principles of the invention are defined by the appended claims.

Claims

1. A dynamic continuous blood glucose monitoring system, characterized by: including skin treatment systems and blood glucose monitoring systems;

the skin treatment system comprises a skin abrasion penetration promoting processor (1); the skin grinding permeation promotion processor (1) comprises a handle body (1-1) with a hollow structure, wherein the front end of the handle body (1-1) is provided with a front end treatment assembly (1-2); the inner cavity of the handle body (1-1) is provided with a processor circuit assembly (1-3), a power supply device (1-4) and a motor (1-5), and an output shaft of the motor (1-5) is connected with a front end processing assembly (1-2) at the front end of the handle body (1-1);

the blood glucose monitoring system comprises a single-use accessory and a monitor (2); the disposable accessory comprises a disposable sensor (3), a disposable transmitter (4), a disposable positioning patch (5), a disposable hydration liquid (6) and a disposable hydration box (7);

the disposable sensor (3) comprises a sensor shell (3-1), a printed circuit board (3-2) arranged on the sensor shell (3-1) and a hydrogel disc (3-3) arranged on the printed circuit board (3-2); the printed circuit board (3-2) is provided with a sensor body (3-2-1) and conductive metal (3-2-2) connected with the sensor body (3-2-1); the hydrogel disc (3-3) is arranged on the upper end face of the sensor body (3-2-1);

The single-use transmitter (4) comprises an upper shell (4-1), a transmitter circuit board (4-2) and a lower shell (4-3); the transmitter circuit board (4-2) is arranged in a cavity formed by the upper shell (4-1) and the lower shell (4-3); the transmitter circuit board (4-2) is provided with a main control chip (4-2-1), a power supply device (4-2-2) for providing power for the main control chip (4-2-1), a wireless communication module (4-2-3) connected with the main control chip (4-2-1) and used for transmitting data to the monitor (2), a conductive spring piece (4-2-4) connected with the main control chip (4-2-1) and used for connecting the disposable sensor (3), and a trigger switch (4-2-5) triggered by the disposable sensor (3) and used for controlling the on-off of a circuit in the transmitter circuit board (4-2); when the disposable transmitter (4) and the disposable sensor (3) are in matched connection, a sensor shell (3-1) of the disposable sensor (3) is in matched connection with an upper shell (4-1) of the disposable transmitter (4), and conductive metal (3-2-2) on a printed circuit board (3-2) in the disposable sensor (3) is in contact with a conductive spring piece (4-2-4) on the transmitter circuit board (4-2) in the disposable transmitter (4);

the disposable positioning patch (5) comprises a positioning patch (5-1), a positioning shell (5-2) arranged on the upper end surface of the positioning patch (5-1) and centrifugal paper (5-3) arranged on the lower end surface of the positioning patch (5-1); the lower end face of the positioning paste (5-1) is provided with adhesive; the positioning shell (5-2) is of a box-shaped structure with an open upper end;

The single-use hydration liquid (6) is used for activating the hydrogel disc (3-3) on the printed circuit board (3-2) in the single-use sensor (3);

a hydration tank matched with a sensor shell (3-1) of the disposable sensor (3) is arranged in the disposable hydration box (7); the processor circuit assembly (1-3) comprises a circuit board (1-3-1), a main control module (1-3-2) arranged on the circuit board (1-3-1), a skin impedance acquisition module (1-3-3) and a motor driving module (1-3-4), wherein the skin impedance acquisition module is electrically connected with the main control module (1-3-2); the motor driving module (1-3-4) receives a control signal of the main control module (1-3-2) through the motor driving chip so as to control the rotation of the motor (1-5);

the front end of the handle body (1-1) is provided with a mounting port (1-1-1) communicated with the inner cavity of the handle body (1-1), and the mounting port (1-1-1) is provided with a front end processing assembly (1-2); the front end processing assembly (1-2) comprises a head cover (1-2-1) detachably connected to the handle body (1-1) at the outer side of the mounting port (1-1-1), a top end cover (1-2-2) sleeved on the head cover (1-2-1) and a disposable processing head (1-2-3);

the machine head cover (1-2-1) is of a cover body structure with an opening at the rear end, which is made of conductive materials, the front end face of the machine head cover is provided with a cover body through hole (1-2-1-1) penetrating up and down, and the machine head cover (1-2-1) is detachably connected to the mounting opening (1-1-1) of the handle body (1-1) through the opening at the rear end; the head cover (1-2-1) is connected with the processor circuit assembly (1-3) through a power supply wire arranged inside;

The top end cover (1-2-2) comprises a connecting cover (1-2-2-1) at the bottom end and a hollow contact end (1-2-2-2) arranged on the front end surface of the connecting cover (1-2-2-1); the rear end of the connecting cover (1-2-2-1) is clamped at the front end of the head cover (1-2-1); the front end face and the outer surface of the top end cover (1-2-2) are provided with conductive coatings at the parts which are matched and connected with the head cover (1-2-1); a connecting cover through hole (1-2-2-3) is arranged on the connecting cover (1-2-2-1) in the contact end (1-2-2-2);

the disposable treatment head (1-2-3) is a cylinder body with an opening at the rear end and made of conductive materials, and the front end surface of the cylinder body is provided with a convex grinding strip (1-2-3-1);

the machine head cover (1-2-1) is matched with the top end cover (1-2-2) and then connected to the mounting opening (1-1-1) of the handle body (1-1), and an output shaft (1-5-1) of the motor (1-5) sequentially penetrates through the cover body through hole (1-2-1-1) and the connecting cover through hole (1-2-2-3) and then protrudes out of the front end face of the connecting cover (1-2-2-1); the disposable treatment head (1-2-3) is sleeved at the outer end of an output shaft (1-5-1) of the motor (1-5), and the output shaft (1-5-1) of the motor (1-5) is electrically connected with a skin impedance acquisition module (1-3-3) of the processor circuit assembly (1-3) through a feedback wire arranged inside; the sensor shell (3-1) is of a box-shaped structure with an opening at the lower end and comprises a sensor top plate (3-1-1) and a sensor coaming (3-1-2) arranged on the outer periphery of the lower end surface of the sensor top plate (3-1-1); the upper end face of the sensor top plate (3-1-1) is provided with an upward protruding sensor boss (3-1-3), and the middle position of the sensor boss (3-1-3) is provided with a downward recessed mounting groove (3-1-4); the sensor coaming (3-1-2) is provided with a fixing notch (3-1-5); a switch trigger block (3-1-6) protruding downwards is arranged on the lower end surface of the sensor top plate (3-1-1); the outer side part of the sensor boss (3-1-3) on the sensor top plate (3-1-1) is provided with a plurality of ventilation holes (3-1-3-1) which penetrate through the mounting groove (3-1-4) from outside to inside;

The printed circuit board (3-2) is of a bendable plate structure, and the printed circuit board (3-2) is provided with a sensor body (3-2-1) and conductive metal (3-2-2) connected with the sensor body (3-2-1); the sensor body (3-2-1) on the printed circuit board (3-2) is arranged in the mounting groove (3-1-4) of the sensor boss (3-1-3), the printed circuit board (3-2) is bent and fixed on the sensor top plate (3-1-1) through the fixing notch (3-1-5), and the conductive metal (3-2-2) is connected with the sensor body (3-2-1) and then extends to the other end of the printed circuit board (3-2);

the hydrogel disc (3-3) is arranged on the upper end face of the sensor body (3-2-1) of the printed circuit board (3-2), and glucose oxidase is arranged in the hydrogel disc (3-3).

2. A dynamic continuous blood glucose monitoring system according to claim 1, wherein: the mounting groove (3-1-4) of the sensor shell (3-1) is provided with a connecting groove (3-1-7) which is sunken downwards by the outer side sensor boss (3-1-3) of the fixing notch (3-1-5); the center of the mounting groove (3-1-4) on the sensor top plate (3-1-1) is provided with a mounting hole (3-1-8) penetrating up and down; the sensor comprises a sensor shell (3-1), a sensor top plate (3-1-1) and a sensor coaming (3-1-2), wherein a plurality of mounting clamping holes (3-1-9) which penetrate through the sensor top plate (3-1-1) and the sensor coaming (3-1-2) simultaneously are formed in the connecting part of the sensor top plate (3-1-1) and the sensor coaming (3-1-2);

The printed circuit board (3-2) comprises a sensing part (3-2-3), a fixing part (3-2-4) and a connecting part (3-2-5) for connecting the sensing part (3-2-3) and the fixing part (3-2-4), wherein the sensing part (3-2-3), the fixing part (3-2-4) and the connecting part (3-2-5) are of an integrated structure; the sensing part (3-2-3) is a circular plate which is matched and connected with a notch of a mounting groove (3-1-4) on the upper end surface of the sensor shell (3-1); the fixing part (3-2-4) is a U-shaped plate bent to form a U-shaped structure and comprises side plates (3-2-4-1) arranged in parallel and bent plates (3-2-4-2) connected with the side plates (3-2-4-1) at two sides; the connecting part (3-2-5) is a bending plate bent at an obtuse angle, the outer end of the upper part of the connecting part (3-2-5) is connected with the sensing part (3-2-3), and the outer end of the lower part of the connecting part (3-2-5) is connected with the upper side plate (3-2-4-1) of the fixing part (3-2-4); the upper part of the connecting part (3-2-5) and the sensing part (3-2-3) are on the same plane; the side plate (3-2-4-1) of the fixing part (3-2-4) is arranged on a lower plane parallel to the sensing part (3-2-3); the sensor body (3-2-1) is arranged on the sensing part (3-2-3); the conductive metal (3-2-2) is connected with the sensor body (3-2-1) and then sequentially extends to the connecting part (3-2-5) and the fixing part (3-2-4);

when the printed circuit board (3-2) is connected with the sensor shell (3-1) in a matched mode, the lower end face of the sensing part (3-2-3) is fixed in the mounting groove (3-1-4), the upper portion of the connecting part (3-2-5) is arranged in the connecting groove (3-1-7), the fixing part (3-2-4) is clamped on the sensor top plate (3-1-1) of the sensor shell (3-1) from outside to inside through a U-shaped structure of the fixing notch (3-1-5), and the sensor top plate (3-1-1) is clamped between the side plates (3-2-4-1) on two sides.

3. A dynamic continuous blood glucose monitoring system according to claim 1, wherein:

in the disposable transmitter (4), an upper shell (4-1) is of a box-shaped structure with an opening at the lower end and comprises an upper shell top plate (4-1-1) and an upper shell coaming (4-1-2) arranged on the outer periphery of the lower end surface of the upper shell top plate (4-1-1); an upper shell boss (4-1-3) protruding upwards is arranged on the upper shell top plate (4-1-1); an upper shell top plate (4-1-1) at one side of the upper shell boss (4-1-3) is provided with a downward concave fixing groove (4-1-4), and the bottom of the fixing groove (4-1-4) is provided with a through hole (4-1-5) penetrating up and down; a switch through hole (4-1-6) penetrating up and down is arranged on the upper shell top plate (4-1-1);

the transmitter circuit board (4-2) is provided with a main control chip (4-2-1), a power supply device (4-2-2) for providing power for the main control chip (4-2-1), a wireless communication module (4-2-3) connected with the main control chip (4-2-1) and used for transmitting data, a conductive elastic sheet (4-2-4) connected with the main control chip (4-2-1) and used for connecting external hardware, and a trigger switch (4-2-5) for controlling the opening and closing of the whole circuit;

the lower shell (4-3) comprises a lower shell bottom plate (4-3-1) and a lower shell coaming (4-3-2) arranged on the upper end surface of the lower shell bottom plate (4-3-1), and the circumferential outer edge of the lower shell bottom plate (4-3-1) protrudes outside the lower shell coaming (4-3-2);

When the upper shell (4-1), the transmitter circuit board (4-2) and the lower shell (4-3) are connected in a matched mode, the transmitter circuit board (4-2) is arranged on the lower shell bottom plate (4-3-1) on the inner side of the lower shell coaming (4-3-2), and the conducting spring piece (4-2-4) on the transmitter circuit board (4-2) penetrates through the conducting hole (4-1-5) in the fixed groove (4-1-4) and protrudes out of the inner bottom surface of the fixed groove (4-1-4).

4. A dynamic continuous blood glucose monitoring system according to claim 3, wherein:

in the disposable transmitter (4), a sensor through hole (4-1-7) penetrating up and down is arranged in the middle of an upper shell boss (4-1-3) of an upper shell top plate (4-1-1); the transmitter circuit board (4-2) is provided with a temperature sensor (4-2-6) which is connected with the main control chip (4-2-1) and used for detecting temperature, and the temperature sensor (4-2-6) is arranged at the upper end of the power supply device (4-2-2); when the upper shell (4-1), the transmitter circuit board (4-2) and the lower shell (4-3) are installed in a matched mode, the temperature sensor (4-2-6) penetrates through the sensor through hole (4-1-7) from bottom to top and protrudes out of the upper end face of the upper shell top plate (4-1-1);

when the disposable sensor (3) is connected with the disposable transmitter (4) in a matched mode, the temperature sensor (4-2-6) of the transmitter circuit board (4-2) sequentially penetrates through the sensor through hole (4-1-7) and the mounting hole (3-1-8) in the sensor top plate (3-1-1) from bottom to top to prop against the lower end of the sensing part (3-2-3) of the printed circuit board (3-2) in the mounting groove (3-1-4).

5. A dynamic continuous blood glucose monitoring system according to claim 4, wherein: in the disposable transmitter (4), a plurality of mounting clamping blocks (4-1-8) protruding outwards are arranged on the outer side of an upper shell coaming (4-1-2) of an upper shell (4-1), and the mounting clamping blocks (4-1-8) are of slope structures with small upper ends and large lower ends; a plurality of lower shell mounting openings (4-3-3) extending downwards from the upper end are formed in the lower shell coaming (4-3-2);

when the upper shell (4-1) and the lower shell (4-3) of the disposable transmitter (4) are connected in a matched mode, the lower ends of the mounting clamping blocks (4-1-8) on the upper shell coaming (4-1-2) are clamped into the lower shell mounting openings (4-3-3) on the lower shell coaming (4-3-2) from top to bottom.

6. A dynamic continuous blood glucose monitoring system according to claim 1, wherein: the positioning shell (5-2) is of a box-shaped structure with an opening at the upper end and comprises a positioning shell bottom plate (5-2-1) and a positioning shell coaming (5-2-2) arranged on the outer periphery of the upper end surface of the positioning shell bottom plate (5-2-1) along the circumferential direction; a positioning through hole (5-2-3) penetrating up and down is arranged in the middle of the positioning shell bottom plate (5-2-1); the positioning paste (5-1) is provided with an opening which is consistent with the positioning through hole (5-2-3) on the positioning shell bottom plate (5-2-1) in size.

7. A dynamic continuous blood glucose monitoring system according to claim 6, wherein:

A plurality of convex positioning blocks (3-1-11) are arranged on the outer side surface of the sensor coaming (3-1-2) of the sensor shell (3-1); the positioning blocks (3-1-11) are slope structures with small upper ends and large lower ends;

the inner side of the locating shell coaming (5-2-2) is provided with a plurality of inwards-sunken locating clamping grooves (5-2-4), and the locating clamping grooves (5-2-4) are of a downhill structure with gradually increased grooving depth from top to bottom.

8. A dynamic continuous blood glucose monitoring system according to claim 1, wherein: the skin treatment system further comprises a skin treatment device charging means (8); the skin treater charging device (8) comprises a charging device upper cover (8-1), a charging device shell (8-2), a charging device circuit board assembly (8-3) arranged in an inner cavity formed by the charging device upper cover (8-1) and the charging device shell (8-2), and a power interface (8-4) arranged on the outer side of the charging device shell (8-2);

the upper cover (8-1) of the charging device comprises an upper cover plate (8-1-1) and an upper cover coaming arranged on the outer edge of the lower end face of the upper cover plate (8-1-1), a charging port is arranged in the middle of the upper end face of the upper cover plate (8-1-1), an inserting inner cylinder (8-1-3) is formed in the opening of the charging port in a downward extending mode, and the lower end of the inserting inner cylinder (8-1-3) is flush with the lower end of the upper cover coaming;

The charging device shell (8-2) comprises a shell bottom plate (8-2-1) and a shell coaming (8-2-2) arranged on the outer edge of the upper end face of the shell bottom plate (8-2-1), a cylinder (8-2-3) with a hollow structure is arranged in the middle of the upper end face of the shell bottom plate (8-2-1), a charging hole (8-2-4) extending from top to bottom is formed in the upper end face of the cylinder (8-2-3), and when the charging device upper cover (8-1) is connected with the charging device shell (8-2) in a matched mode, the lower end of the inserting inner cylinder (8-1-3) is connected with the cylinder (8-2-3) in a matched mode; a plurality of transmitting coils (8-5) electrically connected with the charging device circuit board assembly (8-3) are wound on the outer side surface of the column body (8-2-3);

an induction coil (1-6) which is used for inducing the magnetic field of a transmitting coil (8-5) in the skin processor charging device (8) is arranged on the inner side of the handle body (1-1); the induction coil (1-6) generates current through magnetic field induction to supply power to the processor circuit assembly (1-3) or store the current to the power supply device (1-4).