CN106983516A - Noninvasive blood glucose detection means - Google Patents
Noninvasive blood glucose detection means Download PDFInfo
- Publication number
- CN106983516A CN106983516A CN201610036499.0A CN201610036499A CN106983516A CN 106983516 A CN106983516 A CN 106983516A CN 201610036499 A CN201610036499 A CN 201610036499A CN 106983516 A CN106983516 A CN 106983516A
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- China
- Prior art keywords
- blood glucose
- sensor
- carrier
- detection means
- computing module
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
- A61B5/14517—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for sweat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1477—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means non-invasive
Abstract
The present invention is a kind of relevant noninvasive blood glucose detection means, it includes a carrier, one sensor, one processing computing module and one is except mismatch block, sensor is located at carrier side and detects glucose content in user's sweat, handle computing module and except mismatch block is located in carrier and is linked with the sensor information, it is respectively calculated glucose and progressive error is produced to sensor than changing and excluding glucose with blood glucose value relation, by above-mentioned structure, user only needs to contact sensor with sweat, through the respective action of sensor and processing computing module, calculate the relation of glucose and blood glucose value, and through the action except mismatch block, prevent glucose to the progressive error produced by sensor, reach the purpose of human body non-intruding blood sugar test whereby.
Description
Technical field
The present invention refers in particular to a kind of noninvasive blood glucose detection means of human body non-intruding blood sugar test to provide a kind of blood glucose machine structure of non-intrusion type.
Background technology
Modern increasingly payes attention to for understanding the demand of physiological status, and for the demand also more and more higher of physiological monitoring device, especially under society's more and more busy life step now, the time of vacating goes to hospital to seem more and more difficult, along with the ciril disease phenomenon of present society is increasingly severe, the demand of health monitoring is increasing.
And in current ciril disease, it is the most extensive with diabetes, suitable many of the complication of diabetes, such as hypoglycemia, DKA, non-ketone hyperosmolar coma, angiocardiopathy, chronic renal failure, PVR, DPN and microangiopathies, multiple complications among above-mentioned, death is may result in when serious, therefore understands that blood glucose value monitoring is a considerable ring.
Current blood sugar test machine, is all mainly the detection pattern of intrusive mood, and the detection pattern of intrusive mood, and user first will produce wound with machine on skin（Use acupuncture mostly）, blood is allowed after wound flows out, is acquired by blood sampling test paper, then blood sampling test paper is tested through blood sugar test machine.
So above-mentioned blood sugar test machine of commonly using to be implicitly present in following point and missing in use, wait to improve：
First, detected for intrusive mood, discomfort can be caused to user in blood collection procedure, and can cause to be difficult to heal to there is the patient of diabetes to manufacture wound.
2nd, often once taken a blood sample collection, a piece of blood sampling test paper will be used, though can ensure that the correctness of detection, heavy financial burden can be caused to user.
Therefore the problem of how solving above-mentioned commonly use and missing, as applicant of the present invention desire most ardently the direction place person that research improves with being engaged in the relevant manufactures of the industry.
The content of the invention
Therefore, applicant of the present invention is in view of above-mentioned missing, it is to collect related data, assessed and consideration via multi-party, and to engage in many years of experience of the industry accumulation, via constantly studying and changing, begin to design the patent of invention person of the noninvasive blood glucose detection means of such a human body non-intruding blood sugar test.
It is a primary object of the present invention to：Through glucose content in sensor detecting sweat, glucose and blood glucose value relation ratio are calculated by processing computing module and is changed, and progressive error is produced to sensor through except mismatch block excludes glucose, by above-mentioned technology, it can be detected for commonly using the intrusive mood present in blood sugar test machine and blood sampling test paper is that the problem of point is intended for single use to be broken through, reach the practical improvement of human body non-intruding blood sugar test.
In order to achieve the above object, solution of the invention is：
A kind of noninvasive blood glucose detection means, comprising：
One carrier；
At least one is located at the carrier side and detects the sensor of glucose content in sweat；
One is located in the carrier and is linked with the sensor information, and carries out calculating processing computing module of the glucose with blood glucose value relation than conversion；
One in the carrier and with the processing computing module Info Link, and exclude that glucose produces progressive error to sensor remove mismatch block.
Further, the carrier is worn for aspect ring-like on the other hand and for user.
Further, the information providing module that the carrier is learnt at one side provided with an offer blood glucose value information to user, and the information providing module and the processing computing module Info Link.
Further, the information providing module includes a display unit and a phonation unit, and blood glucose value is shown through picture or sound prompting is learnt to user.
Further, in the carrier provided with one by the information transmission modular of blood glucose value information transfer to other information product, and the information transmission modular and the processing computing module Info Link.
Further, the sensor has at least one electrode layer being located at carrier side, coats the wall of the electrode layer and on the wall and for the reaction liquid layer with contact human skin, and the reaction liquid layer absorbs the electronics of glucose in sweat, the electric charge that the reaction liquid layer obtains after electronics will increase, and the sensor is sensed voltage change.
Further, the sensor preferably sets quantity to be more than three, avoids signal loss to be disturbed with potential difference whereby.
Further, the processing computing module calculates according to the voltage change of the sensor and changes out glucose and blood glucose value relation ratio.
Further, the mode of electronic calibration should be passed through except mismatch block, produced error is influenceed by sweat to improve Metal contacts, it is ensured that the glucose that the processing computing module is calculated is with blood glucose value relation than keeping correct.
By above-mentioned structure, user wears carrier with, sensor is set to be contacted with sweat, when sweat and sensor contacts, sensor will in dereaction sweat glucose content, and according to the content of these glucose, processing computing module can learn current potential and electron stream difference, and can calculate glucose and blood glucose value relation ratio through this difference, calculate the blood glucose value of currently used person, and under being used for a long time, sweat can produce progressive error to sensor, cause to test misalignment, and pass through the electronic calibration except mismatch block, glucose can be excluded progressive error is produced to sensor, thus user can correctly measure blood glucose value, reach the purpose of human body non-intruding blood sugar test.
Brief description of the drawings
Fig. 1 is the stereogram of present pre-ferred embodiments；
Fig. 2 is the schematic block diagram of present pre-ferred embodiments；
Fig. 3 is the use schematic diagram of present pre-ferred embodiments（One）；
Fig. 4 is the use schematic diagram of present pre-ferred embodiments（Two）；
Fig. 5 is the use schematic diagram of present pre-ferred embodiments（Three）；
Fig. 6 is the use schematic diagram of present pre-ferred embodiments（Four）.
【Symbol description】
Carrier 1
Information providing module 11
Display unit 111
Phonation unit 112
Information transmission modular 12
Sensor 2
Electrode layer 21
Wall 22
React liquid layer 23
Handle computing module 3
Except mismatch block 4.
Embodiment
To reach above-mentioned purpose and effect, the technology used in the present invention means and construction, hereby draw as follows with regard to its feature of present pre-ferred embodiments elaborate and function, understand completely in order to sharp.
Please coordinate simultaneously refering to shown in Fig. 1 to Fig. 6, being the stereogram of present pre-ferred embodiments to using schematic diagram（Four）, it can be clearly seen from the figure that the present invention includes：
One carrier 1；
One is located at the side of carrier 1 and detects the sensor 2 of glucose content in sweat, and sensor 2 has at least one electrode layer 21 being located at carrier side, the wall 22 of jacketed electrode layer 21 and on wall 22 and for the reaction liquid layer 23 with contact human skin；
One in the carrier 1 and with the Info Link of sensor 2, and carry out calculating processing computing module 3 of the glucose with blood glucose value relation than conversion；
One in the carrier 1 and with the Info Link of processing computing module 3, and exclude that glucose produces progressive error to sensor 2 remove mismatch block 4.
Above-mentioned carrier 1 is aspect ring-like on the other hand, and the information providing module 11 that carrier 1 is learnt at one side provided with an offer blood glucose value information to user, and the information providing module 11 and the Info Link of processing computing module 3, information providing module 11 includes a display unit 111 and a phonation unit 112, and blood glucose value is shown through picture or sound prompting is learnt to user.
Provided with one by the information transmission modular 12 of blood glucose value information transfer to other information product in above-mentioned carrier 1, and the information transmission modular 12 and the Info Link of processing computing module 3.
Above-mentioned sensor preferably sets quantity to be more than three, signal loss is avoided to be disturbed with potential difference whereby, and its electrode layer 21 includes conducting metal or conductive material, and the shape of electrode layer 21, which is not kept within bounds, to be circular or square etc., attached most importance to the surface area for providing fixed, and wall 22 includes filament or has the gel one of which of semiconduction, and the purpose for jacketed electrode layer 21 to reach interval and avoid short circuit, electrode layer 21 is set to be not directly contacted with human body skin, and because reaction liquid layer 23 includes glucose ferment, therefore obtained and the glucose response in sweat when reaction liquid layer 23 and contact human skin, the generation of voltage and electron stream is set to make a variation.
The present invention is a kind of blood sugar detection apparatus of non-intrusion type, first illustrate that the present invention reaches the measuring technology means of non-intrusion type, people is in general life, more or less can all there is sweat outflow on skin, and include this element of glucose in sweat, and electron stream can be produced after breakdown of glucose and voltage is caused, when blood glucose value is higher in human body, the amount of its glucose is more, and sensor of the invention 2 absorbs the electronics of glucose in sweat through reaction liquid layer 23, the electric charge that the reaction liquid layer 23 obtains after electronics will increase, the sensor 2 is set to sense voltage change, thus, processing computing module 3 will calculate according to the voltage change of the sensor 2 and change out glucose and blood glucose value relation ratio, the current blood glucose value of user can just be learnt, and need not be reached by the way of human body intrusion.
It refer to Fig. 3, to be schematically illustrate using what is worn, carrier 1 is the aspect of bracelet type, only need to be sheathed on wrist or arm when using, now the reaction liquid layer 23 on sensor 2 will be contacted with skin, consequently, it is possible to can carry out contacting with sweat, above-mentioned Cleaning Principle is passed through again, reaches the purpose of blood sugar test.
It refer to Fig. 4, to learn the schematically illustrate of blood glucose value information through information providing module 11, after blood glucose measurement has been carried out, blood glucose value information will pass through display unit 111 or phonation unit 112, by through picture show or sound prompting in the way of be supplied to user to learn.
Fig. 5 is refer to, to pass through information transmission modular 12 by the schematically illustrate of blood glucose value information transfer to other information product, first by other information product（Such as intelligent mobile phone）Enter row information pairing with the blood sugar detection apparatus of the present invention, after blood glucose measurement is completed, blood glucose value information will be transferred to information products through information transmission modular 12, and hereafter user directly can just be watched from information products, reach the purpose for learning blood glucose value.
It refer to Fig. 6, to pass through glucose except mismatch block 4 to the schematically illustrate of the progressive error exclusion produced by sensor 2, after using a period of time, reaction liquid layer 23 on sensor 2 will be influenceed by sweat, make to contain micro glucose on reaction liquid layer 23, thus, when carrying out blood glucose measurement, its result will misalignment, and under serious situation, an action may be caused（Not yet contacted with sweat）Error situation with regard to measuring hyperglycaemia value, in this regard, except mode of the mismatch block 4 through electronic calibration, influence produced error by sweat to improve reaction liquid layer 23, to ensure that glucose that the processing computing module 3 calculated and blood glucose value relation are more correct than holding.
Therefore the noninvasive blood glucose detection means of the present invention is that can improve the key problem in technology commonly used to be：
With the phenomenon of electron stream, voltage can be produced after breakdown of glucose, corresponded to using this characteristic and produce sensor 2 and processing computing module 3, glucose and blood glucose value relation ratio are changed out to calculate, and above-mentioned explanation structure and technological means are passed through, the advantage purpose of human body non-intruding blood sugar test can be reached.
Only, the foregoing is merely illustrative of the preferred embodiments of the present invention, the scope of the claims that is non-therefore arresting the limit present invention, therefore such as with the simple modification carried out by description of the invention and schema content and equivalent structure change, in the scope of the claims that the present invention all should be similarly contained in, Chen Ming is given in conjunction.
Claims (9)
1. a kind of noninvasive blood glucose detection means, it is characterised in that include：
One carrier；
At least one is located at the carrier side and detects the sensor of glucose content in sweat；
One is located in the carrier and is linked with the sensor information, and carries out calculating processing computing module of the glucose with blood glucose value relation than conversion；
One in the carrier and with the processing computing module Info Link, and exclude that glucose produces progressive error to sensor remove mismatch block.
2. noninvasive blood glucose detection means as claimed in claim 1, it is characterised in that：The carrier is the aspect of a bracelet type worn for user.
3. noninvasive blood glucose detection means as claimed in claim 1, it is characterised in that：The information providing module that the carrier is learnt at one side provided with an offer blood glucose value information to user, and the information providing module and the processing computing module Info Link.
4. noninvasive blood glucose detection means as claimed in claim 3, it is characterised in that：The information providing module includes a display unit and a phonation unit, and blood glucose value is shown through picture or sound prompting is learnt to user.
5. noninvasive blood glucose detection means as claimed in claim 1, it is characterised in that：Provided with one by the information transmission modular of blood glucose value information transfer to other information product in the carrier, and the information transmission modular and the processing computing module Info Link.
6. noninvasive blood glucose detection means as claimed in claim 1, it is characterised in that：The sensor has at least one electrode layer being located at carrier side, coats the wall of the electrode layer and on the wall and for the reaction liquid layer with contact human skin, and the reaction liquid layer absorbs the electronics of glucose in sweat, the electric charge that the reaction liquid layer obtains after electronics will increase, and the sensor is sensed voltage change.
7. noninvasive blood glucose detection means as claimed in claim 6, it is characterised in that：The sensor preferably sets quantity to be more than three, avoids signal loss to be disturbed with potential difference whereby.
8. noninvasive blood glucose detection means as claimed in claim 6, it is characterised in that：The processing computing module calculates according to the voltage change of the sensor and changes out glucose and blood glucose value relation ratio.
9. noninvasive blood glucose detection means as claimed in claim 6, it is characterised in that：This passes through the mode of electronic calibration except mismatch block, and produced error is influenceed by sweat to improve Metal contacts, it is ensured that the glucose that the processing computing module is calculated is with blood glucose value relation than keeping correct.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610036499.0A CN106983516A (en) | 2016-01-20 | 2016-01-20 | Noninvasive blood glucose detection means |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610036499.0A CN106983516A (en) | 2016-01-20 | 2016-01-20 | Noninvasive blood glucose detection means |
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| CN106983516A true CN106983516A (en) | 2017-07-28 |
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| CN201610036499.0A Pending CN106983516A (en) | 2016-01-20 | 2016-01-20 | Noninvasive blood glucose detection means |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108742647A (en) * | 2018-04-30 | 2018-11-06 | 中山市京春电子科技有限公司 | A kind of portable blood sugar detection device |
| CN109770915A (en) * | 2018-12-17 | 2019-05-21 | 新绎健康科技有限公司 | A kind of system and method obtaining glucose in blood and ion concentration based on sweat |
| CN111812083A (en) * | 2020-07-15 | 2020-10-23 | 京东方科技集团股份有限公司 | Body fluid detection device, system and method |
| CN111938664A (en) * | 2020-08-13 | 2020-11-17 | 合肥安时智造科技有限公司 | Wearable intelligent noninvasive blood glucose monitoring device based on microfluidic technology |
| CN113545779A (en) * | 2020-04-23 | 2021-10-26 | 智准生医科技股份有限公司 | Biological information sensing patch |
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| CN101005798A (en) * | 2004-07-01 | 2007-07-25 | 维沃医学公司 | Non-invasive glucose measurement |
| TWM352999U (en) * | 2008-09-11 | 2009-03-21 | Ebiologic Technology Co Ltd | Wrist blood sugar monitoring device |
| CN101489470A (en) * | 2006-06-12 | 2009-07-22 | 维沃医学公司 | Patches, systems, and methods for non-invasive glucose measurement |
| TW201015067A (en) * | 2008-09-09 | 2010-04-16 | Vivomedical Inc | Sweat collection devices for glucose measurement |
| CN101854857A (en) * | 2007-11-09 | 2010-10-06 | 欧姆龙健康医疗事业株式会社 | System for accurately measuring blood component concentration and method of controlling the system |
| CN104280444A (en) * | 2014-10-15 | 2015-01-14 | 南京皓运投资管理有限公司 | Sweat collection and analysis system and manufacturing method thereof |
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Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101005798A (en) * | 2004-07-01 | 2007-07-25 | 维沃医学公司 | Non-invasive glucose measurement |
| CN101489470A (en) * | 2006-06-12 | 2009-07-22 | 维沃医学公司 | Patches, systems, and methods for non-invasive glucose measurement |
| CN101854857A (en) * | 2007-11-09 | 2010-10-06 | 欧姆龙健康医疗事业株式会社 | System for accurately measuring blood component concentration and method of controlling the system |
| TW201015067A (en) * | 2008-09-09 | 2010-04-16 | Vivomedical Inc | Sweat collection devices for glucose measurement |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108742647A (en) * | 2018-04-30 | 2018-11-06 | 中山市京春电子科技有限公司 | A kind of portable blood sugar detection device |
| CN109770915A (en) * | 2018-12-17 | 2019-05-21 | 新绎健康科技有限公司 | A kind of system and method obtaining glucose in blood and ion concentration based on sweat |
| CN113545779A (en) * | 2020-04-23 | 2021-10-26 | 智准生医科技股份有限公司 | Biological information sensing patch |
| CN111812083A (en) * | 2020-07-15 | 2020-10-23 | 京东方科技集团股份有限公司 | Body fluid detection device, system and method |
| CN111938664A (en) * | 2020-08-13 | 2020-11-17 | 合肥安时智造科技有限公司 | Wearable intelligent noninvasive blood glucose monitoring device based on microfluidic technology |
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Application publication date: 20170728 |