CN106975164A - The radiotherapy unit of MRI guiding - Google Patents

The radiotherapy unit of MRI guiding Download PDF

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Publication number
CN106975164A
CN106975164A CN201710213341.0A CN201710213341A CN106975164A CN 106975164 A CN106975164 A CN 106975164A CN 201710213341 A CN201710213341 A CN 201710213341A CN 106975164 A CN106975164 A CN 106975164A
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CN
China
Prior art keywords
linear accelerator
drum type
type brake
radiotherapy
brake magnet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710213341.0A
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Chinese (zh)
Inventor
汤卿
熊瑞平
黄春强
姚进
吴大可
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sichuan University
Original Assignee
Sichuan University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sichuan University filed Critical Sichuan University
Priority to CN201710213341.0A priority Critical patent/CN106975164A/en
Publication of CN106975164A publication Critical patent/CN106975164A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077Beam delivery systems
    • A61N5/1083Robot arm beam systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1042X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy with spatial modulation of the radiation beam within the treatment head
    • A61N5/1045X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy with spatial modulation of the radiation beam within the treatment head using a multi-leaf collimator, e.g. for intensity modulated radiation therapy or IMRT
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1049Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1055Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using magnetic resonance imaging [MRI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092Details
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092Details
    • A61N2005/1094Shielding, protecting against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092Details
    • A61N2005/1097Means for immobilizing the patient

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Robotics (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

The invention provides a kind of radiotherapy unit of MRI guiding, including MR imaging apparatus and linear accelerator, the main magnet of the MR imaging apparatus is drum type brake magnet, it is provided with the middle part of the drum type brake magnet perpendicular to the gap of axis, the linear accelerator sends X-ray through the gap directive isocenter point, it is characterised in that:The drum type brake magnet can be rotated around perpendicular to ground and by the axis of isocenter point;The linear accelerator is arranged on robot, and robot carries linear accelerator motion so that the ray that linear accelerator is sent at any time can be from the isocenter point of the gap directive radiotherapy.Radiotherapy unit burnt skin ratio of the present invention is high, the non-co-planar treatment in center, damage of the mitigation to patient such as can realize to patient.

Description

The radiotherapy unit of MRI guiding
Technical field
The invention belongs to technical field of medical instruments, and in particular to a kind of radiotherapy unit of MRI guiding.
Background technology
In current radiotherapy, widely used image guidance techniques carry out image guiding, this meeting using X-ray mostly Allow patient by extra more x-ray dose, larger injury is caused to patient.Mri guided technology, by pair Human body does not cause the advantage of additional injuries to be paid attention to and developed.
In addition, wait center it is non-co-planar treatment have become important development trend, it can cause patient target area by Higher radiological dose, and it is relatively low in the radiological dose that normal surrounding tissue is subject to, so as to protect the normal of human body as much as possible Tissue.
However, at present guide of magnetic resonant image radiotherapy system be substantially all belong to wait center co-planar treat, burnt skin Than relatively low, while tumour cell is killed, the infringement caused to patient's normal structure is larger.
The content of the invention
In order to overcome in the prior art above shortcomings it is high there is provided a kind of burnt skin ratio, the center such as can realize to patient The robot radiation therapy device of the MRI guiding of non-co-planar treatment.
The technical solution adopted by the present invention is:A kind of radiotherapy unit of MRI guiding, including MR imaging apparatus and Linear accelerator, the main magnet of the MR imaging apparatus be provided with the middle part of drum type brake magnet, the drum type brake magnet it is vertical Directly in the gap of axis, the linear accelerator sends X-ray through the gap directive isocenter point, it is characterised in that:Institute Stating drum type brake magnet can rotate around perpendicular to ground and by the axis of isocenter point;The linear accelerator is arranged on machine On people, robot carries linear accelerator motion so that the ray that linear accelerator is sent at any time can be from described Gap directive same point, the i.e. isocenter point of radiotherapy.
In such scheme, the drum type brake magnet produces magnetic field, the direction in the magnetic field and cylinder by superconducting coil The axis parallel of formula magnet.
In such scheme, the linear accelerator is X-band linear accelerator.
In such scheme, the ray that the linear accelerator is sent is substantially vertical with the magnetic direction of magnetic resonance equipment.
In such scheme, the ray that the linear accelerator is sent carries out the centers such as limit Shu Houzai directives using collimater Point.
In such scheme, the artificial bottom of machine may move, the mechanical arm configuration of the series connection with 6 frees degree.
In such scheme, entangled outside the linear accelerator by a magnetic shielding cover, the magnetic shielding cover is by soft magnetism material Material is made.
Beneficial effects of the present invention are:(1)The image guiding of radiation therapy process is carried out using magnetic resonance, compared to utilization X-ray, with harmless, the advantages of soft tissue contrast is high;(2)Arc track using linear accelerator along support Rotate, add support and cylinder magnet and rotated around vertical axis, realize and center non-co-planar formula treatment, efficiency are waited to patient Height, burnt skin ratio is high, small to patient trauma(3)Linear accelerator motion is driven using robot, being capable of multi-angle, multi-faceted, height Radiotherapy accurately is carried out to target area.
Brief description of the drawings
Fig. 1 is the structural representation of one embodiment of the present invention.
Fig. 2 is one embodiment of the present invention only top view comprising bottom plate and therapeutic bed.
In figure, 1 robot;2 linear accelerators;3 collimaters;4 drum type brake magnets;5 gaps;6 supporting members;7 bottom plates;8 control Treat bed;9 isocenter points.
Specific embodiment
As shown in figure 1, a kind of radiotherapy unit of MRI guiding, including MR imaging apparatus and linear accelerator 2, The main magnet of the MR imaging apparatus is drum type brake magnet 4, and the middle part of the drum type brake magnet 4 is provided with perpendicular to axis Gap 5, the linear accelerator sends X-ray through the gap directive isocenter point 9, and drum type brake magnet 4 can be around vertical Rotated in ground and by the axis B-B of isocenter point 9;Linear accelerator 2 is arranged in robot 1, and robot 1 carries straight line Accelerator 2 is moved so that the ray that linear accelerator 2 is sent at any time can be from the directive radiotherapy of gap 5 Isocenter point 9.
Because X-band linear accelerator small volume, light weight, are easily captured by robot 1, so selecting X-band here Linear accelerator.The ray that linear accelerator 1 is sent carries out limit Shu Houzai directives isocenter point 9, collimater 3 using collimater 3 Prioritizing selection multi-diaphragm collimator, naturally it is also possible to for circular collimater, square collimater etc..The bottom of robot 1 may move, can be with The position of a most suitable radiotherapy is positioned at as needed, and is the mechanical arm configuration of the series connection with 6 frees degree, more preferably From multi-faceted, multi-angle irradiation target area.The outside of linear accelerator 1 is entangled by a magnetic shielding cover, and magnetic shielding cover is by soft magnetism material Material is made, and soft magnetic materials can be soft iron, silicon steel, permalloy or ferroaluminium etc., and cheap soft iron is selected here.
MR imaging apparatus is made up of drum type brake magnet 4 and bearing, and bearing includes bottom plate 7, supporting member 6, and bottom plate 7 can be with Axis B-B around isocenter point excessively and perpendicular to ground is rotated, and supporting member 6 is arranged on bottom plate 7, and drum type brake magnet 4 is connected In on supporting member 6.
Such as Fig. 2(a)Shown, under original state, the bottom plate 7 of magnetic resonance equipment aligns with therapeutic bed 8, and linear accelerator is flat Rotated in a of face and patient has been carried out to penetrate treatment;Then, whole MR imaging apparatus stops around the axis B-B θ that turn an angle Firmly, linear accelerator proceeds radiotherapy in plane b, can according to actually choose treatment plane position and quantity, So as to reach the purpose of non-co-planar treatment.
In the present invention, the purpose of non-co-planar isocentric treatment, therapeutic bed 8 and patient are reached(Not shown in figure)It is fixed, magnetic Resonance image-forming equipment is rotated, and robot 1 carries the synchronous axial system of linear accelerator 2, so does primarily to not brought to patient Discomfort and fear, at the same also avoid patient rotation when organ between mutual compression and deform and influence radiotherapeutic effect. Certainly, rotated if being not desired to heavy MR imaging apparatus, can according to the knowledge of relative motion, be designed to therapeutic bed 8 with Patient rotates, and the form that MR imaging apparatus is fixed, and can also reach identical purpose.
In addition, for support cylinder formula magnet 4 and can relatively rotate, here with supporting member 6, there can also be it certainly His form, can such as be supported at the two ends of drum type brake magnet 4 with rolling bearing.
In addition, in order to realize non-co-planar treatment, it is necessary to which drum type brake magnet 4 is rotated relative to therapeutic bed.Because drum type brake magnet 4 There is gap centre, it is not necessary to rotated around axis A-A, so the rotation relative to therapeutic bed only has two kinds of forms:(1)With Guo Deng centers The 9 and axis B-B perpendicular to ground is put to rotate;(2)To cross isocenter point 9 and parallel to ground and vertical with therapeutic bed axis Axis(Not shown in figure)Rotate, it is contemplated that in order to realize it is relatively easy reduced the complexity of whole system, while again not Made troubles, have selected here to patient with Mobile treatment table(1), and be that therapeutic bed 8 is fixed.Of course, it is possible to imagine , utilize rotation formula(2)Non-co-planar treatment can also be realized.
The operation principle of the present embodiment is:Before radiotherapy, patient is transferred to appropriate position by therapeutic bed 8 so that patient's Target area is located substantially at after the isocenter point 9 of the radiotherapy system, and MR imaging apparatus is opened, and determines target area in three dimensions Position, carries out pendulum position to patient followed by therapeutic bed 8, the target area of patient is exactly in the isocenter point of the radiotherapy system At 9.Then, robot 1 carries linear accelerator 2 and rotated around circular gap 5 around axle A-A, and linear accelerator 2 is sent out Emergent ray directive after collimater 3 limits beam is located at the target area of isocenter point 9, just realizes to target area in the coplanar of some plane Treatment.Then, bearing around axis B-B turn an angle after stop, robot 1 carry linear accelerator 2 continue irradiate shine Penetrate, just realize coplanar treatment of the linear accelerator 2 to target area in another plane.According to actual conditions, selection two or The plane of the multiple linear accelerator irradiations of person, just realizes the non-co-planar treatment to target area.It is envisioned that radiographic source here 1, which sends treatment of the ray to target area, can be arc pulling type treatment or be interrupted dot type treatment, in order to improve efficiency, this In prioritizing selection the former.Over the course for the treatment of, real time imagery is carried out to target area using MR imaging apparatus, especially to exhaling Dynamic target area, and the treatment of Real Time Observation target area are aspirated, in order to judge whether to need to change treatment according to treatment Plan.
The above described is only a preferred embodiment of the present invention, not making any formal limitation to the present invention.Appoint What those skilled in the art, without departing from the scope of the technical proposal of the invention, all using the side of the disclosure above Method and technology contents make many possible variations and modification to technical solution of the present invention, or are revised as the equivalent reality of equivalent variations Apply example.Therefore, every content without departing from technical solution of the present invention, the technical spirit according to the present invention is done to above example Any simple modifications, equivalents, and modifications, still fall within technical solution of the present invention protection in the range of.

Claims (7)

1. a kind of radiotherapy unit of MRI guiding, including MR imaging apparatus and linear accelerator, the magnetic resonance imaging The main magnet of equipment is to be provided with the middle part of drum type brake magnet, the drum type brake magnet perpendicular to the gap of axis, and the straight line adds Fast device sends X-ray through the gap directive isocenter point, it is characterised in that:The drum type brake magnet can be around perpendicular to ground Face and the axis rotation for passing through isocenter point;The linear accelerator is arranged on robot, and robot carries linear accelerator fortune It is dynamic so that the ray that linear accelerator is sent at any time can be from the isocenter point of the gap directive radiotherapy.
2. radiotherapy unit according to claim 1, it is characterised in that:The drum type brake magnet by superconducting coil come Produce magnetic field, the direction in the magnetic field and the axis parallel of drum type brake magnet.
3. radiotherapy unit according to claim 1, it is characterised in that:The linear accelerator is that X-band straight line adds Fast device.
4. radiotherapy unit according to claim 1, it is characterised in that:Ray and magnetic that the linear accelerator is sent The magnetic direction of resonant device is substantially vertical.
5. the radiotherapy unit according to claim 1,2 or 3, it is characterised in that:What the linear accelerator was sent penetrates Line carries out limit Shu Houzai directive isocenter points using collimater.
6. according to claim 1 penetrate treatment system, it is characterised in that:The artificial bottom of machine may move, with 6 The mechanical arm configuration of the series connection of the individual free degree.
7. the radiotherapy unit according to claim 3,4 or 5, it is characterised in that:By one outside the linear accelerator Individual magnetic shielding cover is entangled, and the magnetic shielding cover is made up of soft magnetic materials.
CN201710213341.0A 2017-04-01 2017-04-01 The radiotherapy unit of MRI guiding Pending CN106975164A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710213341.0A CN106975164A (en) 2017-04-01 2017-04-01 The radiotherapy unit of MRI guiding

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710213341.0A CN106975164A (en) 2017-04-01 2017-04-01 The radiotherapy unit of MRI guiding

Publications (1)

Publication Number Publication Date
CN106975164A true CN106975164A (en) 2017-07-25

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105251135A (en) * 2015-08-11 2016-01-20 北京健联医疗科技有限公司 Precise robot radiotherapy system under guidance of MRI
CN105920746A (en) * 2016-06-16 2016-09-07 四川大学 Radiation therapy device

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105251135A (en) * 2015-08-11 2016-01-20 北京健联医疗科技有限公司 Precise robot radiotherapy system under guidance of MRI
CN105920746A (en) * 2016-06-16 2016-09-07 四川大学 Radiation therapy device

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Application publication date: 20170725

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