CN106974963A - A kind of anticancer honeyed bolus and preparation method thereof - Google Patents
A kind of anticancer honeyed bolus and preparation method thereof Download PDFInfo
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- CN106974963A CN106974963A CN201710181735.2A CN201710181735A CN106974963A CN 106974963 A CN106974963 A CN 106974963A CN 201710181735 A CN201710181735 A CN 201710181735A CN 106974963 A CN106974963 A CN 106974963A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/65—Amphibians, e.g. toads, frogs, salamanders or newts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
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Abstract
The invention discloses a kind of anticancer honeyed bolus, it is made up of drug ingedient and honey, the drug ingedient is made up of the raw material of following parts by weight：12 15 parts of hydrolyzed pearl powder, 9 12 parts of Sculellaria barbata, 9 12 parts of subprostrate sophora, 8 10 parts of purslane, wolf's fang careless 57 parts, 24 parts of Toad Skin；The weight ratio of the honey and drug ingedient is 1.1 1.3:1；And there is provided its preparation method.The anticancer honeyed bolus is using the pearl with cancer suppressing action as primary raw material, pearl is using the pearl powder after hydrolysis, and be used in combination with the Chinese herbal medicine such as Sculellaria barbata, subprostrate sophora, purslane, wolf's fang grass, Toad Skin, with suppression cancer antitumaous effect, reference is provided for the Chinese traditional treatment of cancer.
Description
Technical field
The invention belongs to Chinese patent drug technique field, in particular it relates to a kind of anticancer honeyed bolus and preparation method thereof.
Background technology
Cancer, refers to the malignant tumour originating from epithelial tissue, is a most common class in malignant tumour, general people institute
" cancer " said traditionally refers to all malignant tumours.
The reason for inducing cancer, has external source, also there is endogenous.Such as we are by Exposure to Sunlight, and induced by ultraviolet irradiation DNA replication dna is wrong
By mistake, it is physical factor.Cancer mutagens in food/environment, are chemical factors.Hepatitis, is viral factor.These three, are main
The modificator gene variation wanted, moves towards the extrinsic factor of cancer.Castle's intrinsic factor generates duplication when referring to because of cell self-dsivision
Mistake, in the course of time, incorrect integration are got up, and form canceration.
The treatment method of current cancer includes operation, radiotherapy, chemotherapy and tcm therapy, and wherein tcm therapy is that most have hair
A kind of method of potentiality is opened up, but at present in the treatment of cancer or based on western medicine.Therefore, how theory of traditional Chinese medical science is utilized
Treating cancer is significant there is provided a kind of traditional Chinese medical science means of cancer.
The content of the invention
First purpose of the present invention is to solve the above problems that there is provided a kind of anticancer honeyed bolus.
Second object of the present invention is to provide the preparation method of above-mentioned honeyed bolus.
The purpose of the present invention is implemented by the following technical programs：
A kind of anticancer honeyed bolus, is made up of drug ingedient and honey, and the drug ingedient is made up of the raw material of following parts by weight：
12-15 parts of hydrolyzed pearl powder, 9-12 parts of Sculellaria barbata, 9-12 parts of subprostrate sophora, 8-10 parts of purslane, 5-7 parts of wolf's fang grass, toad
2-4 parts of skin；
The weight ratio of the honey and drug ingedient is 1.1-1.3:1.
It is preferred that, the drug ingedient is made up of the raw material of following parts by weight：
15 parts of hydrolyzed pearl powder, 10 parts of Sculellaria barbata, 10 parts of subprostrate sophora, 8 parts of purslane, wolf's fang careless 6 parts, 4 parts of Toad Skin.
The preparation method of above-mentioned anticancer honeyed bolus, comprises the following steps：
（1）The preparation of hydrolyzed pearl powder：Pearl is milled, add water mixing, adjusts pH value, heating is stirred, dried, must hydrolyze
Pearl powder；
（2）Milling：Sculellaria barbata, subprostrate sophora, purslane, wolf's fang grass, Toad Skin are clayed into power respectively, 100 mesh sieves is crossed, obtains half
Lotus powder, subprostrate sophora powder, purslane powder, wolf's fang grass meal, Toad Skin powder；
（3）Refined honey：Honey is heated, when occur light red foam, hand-held viscosity it is stronger when, you can；
（4）Modulation：By step（1）Obtained hydrolyzed pearl powder and step（2）Obtained Sculellaria barbata powder, subprostrate sophora powder, purslane
Powder, wolf's fang grass meal, Toad Skin powder are well mixed, and add step（3）The honey of refining, is stirred continuously；
（5）By step（4）Medicine after modulation carries out rubbing, is then divided into pill, produces.
Further, the step（1）In, the weight ratio of pearl and water after milling is 1:5-8, uses vinegar acid for adjusting pH value
To 4.5-4.8, heating-up temperature is 50-60 DEG C, and stir speed (S.S.) is 20-30rpm, and mixing time 3-4h, drying temperature is 70-75
℃.
Further, the step（3）The temperature of middle honey heating is 110-115 DEG C.
Further, the step（5）Aseptically carry out.
Pearl it is medicinal：《Compendium of Materia Medica》Described in：Salty sweet nontoxic, the relieving palpitation point mesh of trembling with fear of pearl taste；Pearl applies face, makes us profit
The good color in pool, applies brothers, removes skin hangnail；Phlegm is fallen, except face spot, antidiarrheal；Except children's fever (of children) accompanied by fear, pacify soul；Only pass out semen gonorrhoea, solve acne
Treat poison.The main component of pearl is the inorganic constituents such as calcium carbonate, and grinds are eaten, and absorptivity is low, and if first being hydrolyzed system
Into pearl powder, then its absorption efficiency can be greatly improved.
The present invention is using hydrolyzed pearl powder as main component, and hydrolyzed pearl powder is easier to be absorbed by the body than ordinary pearl powder,
Its antitumaous effect can be given full play to, Chinese Medical Scutellaria Barbata, subprostrate sophora, purslane, wolf's fang grass, Toad Skin is also added, is made
Honeyed bolus, preparation method is simple, instant.
The invention has the advantages that：
The anticancer honeyed bolus that the present invention is provided, using the pearl with cancer suppressing action as primary raw material, pearl is using the pearl after hydrolysis
Powder, and be used in combination with the Chinese herbal medicine such as Sculellaria barbata, subprostrate sophora, purslane, wolf's fang grass, Toad Skin, with suppression cancer antitumaous effect, it is
The Chinese traditional treatment of cancer, which is provided, uses for reference.
Embodiment
Embodiment 1
A kind of preparation method of anticancer honeyed bolus, comprises the following steps：
（1）The preparation of hydrolyzed pearl powder：Pearl is milled, the water mixing of 5 times of weight is added, with vinegar acid for adjusting pH value to 4.5-
4.8,50 DEG C are heated to, is stirred with 20rpm speed, mixing time 3h, 70 DEG C of drying obtain hydrolyzed pearl powder.
（2）Milling：By Sculellaria barbata 1kg, subprostrate sophora 1kg, purslane 0.8kg, wolf's fang grass 0.6kg, Toad Skin 0.4kg difference
Clay into power, cross 100 mesh sieves, obtain Sculellaria barbata powder, subprostrate sophora powder, purslane powder, wolf's fang grass meal, Toad Skin powder.
（3）Refined honey：Take honey 5.83kg, be heated to 110 DEG C, when occur light red foam, hand-held viscosity it is stronger when, i.e.,
Can.
（4）Modulation：Take step（1）Obtained hydrolyzed pearl powder 1.5kg and step（2）Obtained Sculellaria barbata powder, subprostrate sophora
Powder, purslane powder, wolf's fang grass meal, Toad Skin powder are well mixed, and add step（3）The honey of refining, is stirred continuously uniform.
（5）In an aseptic environment, by step（4）Medicine after modulation carries out rubbing, is then divided into pill, and per ball, weight 5g is left
The right side, is produced.
Embodiment 2
A kind of preparation method of anticancer honeyed bolus, comprises the following steps：
（1）The preparation of hydrolyzed pearl powder：Pearl is milled, the water mixing of 8 times of weight is added, with vinegar acid for adjusting pH value to 4.5-
4.8,60 DEG C are heated to, is stirred with 30rpm speed, mixing time 4h, 75 DEG C of drying obtain hydrolyzed pearl powder.
（2）Milling：By Sculellaria barbata 1.2kg, subprostrate sophora 0.9kg, purslane 0.9kg, wolf's fang grass 0.7kg, Toad Skin 0.3kg
Clay into power respectively, cross 100 mesh sieves, obtain Sculellaria barbata powder, subprostrate sophora powder, purslane powder, wolf's fang grass meal, Toad Skin powder.
（3）Refined honey：Take honey 6.76kg, be heated to 110 DEG C, when occur light red foam, hand-held viscosity it is stronger when, i.e.,
Can.
（4）Modulation：Take step（1）Obtained hydrolyzed pearl powder 1.2kg and step（2）Obtained Sculellaria barbata powder, subprostrate sophora
Powder, purslane powder, wolf's fang grass meal, Toad Skin powder are well mixed, and add step（3）The honey of refining, is stirred continuously uniform.
（5）In an aseptic environment, by step（4）Medicine after modulation carries out rubbing, is then divided into pill, and per ball, weight 5g is left
The right side, is produced.
Embodiment 3
A kind of preparation method of anticancer honeyed bolus, comprises the following steps：
（1）The preparation of hydrolyzed pearl powder：Pearl is milled, the water mixing of 6 times of weight is added, with vinegar acid for adjusting pH value to 4.5-
4.8,55 DEG C are heated to, is stirred with 20rpm speed, mixing time 3.5h, 70 DEG C of drying obtain hydrolyzed pearl powder.
（2）Milling：By Sculellaria barbata 0.9kg, subprostrate sophora 1.2kg, purslane 1kg, wolf's fang grass 0.5kg, 0.2kg points of Toad Skin
Do not clay into power, cross 100 mesh sieves, obtain Sculellaria barbata powder, subprostrate sophora powder, purslane powder, wolf's fang grass meal, Toad Skin powder.
（3）Refined honey：Take honey 6.12kg, be heated to 110 DEG C, when occur light red foam, hand-held viscosity it is stronger when, i.e.,
Can.
（4）Modulation：Take step（1）Obtained hydrolyzed pearl powder 1.3kg and step（2）Obtained Sculellaria barbata powder, subprostrate sophora
Powder, purslane powder, wolf's fang grass meal, Toad Skin powder are well mixed, and add step（3）The honey of refining, is stirred continuously uniform.
（5）In an aseptic environment, by step（4）Medicine after modulation carries out rubbing, is then divided into pill, and per ball, weight 5g is left
The right side, is produced.
The preferred embodiments of the present invention are the foregoing is only, are not intended to limit the invention, although with reference to foregoing reality
Apply example the present invention is described in detail, for those skilled in the art, it still can be to foregoing each implementation
Technical scheme described in example is modified, or carries out equivalent substitution to which part technical characteristic.All essences in the present invention
God is with principle, and any modification, equivalent substitution and improvements made etc. should be included in the scope of the protection.
Claims (6)
1. a kind of anticancer honeyed bolus, is made up of drug ingedient and honey, it is characterised in that the drug ingedient is by following parts by weight
Raw material is constituted：
12-15 parts of hydrolyzed pearl powder, 9-12 parts of Sculellaria barbata, 9-12 parts of subprostrate sophora, 8-10 parts of purslane, 5-7 parts of wolf's fang grass, toad
2-4 parts of skin；
The weight ratio of the honey and drug ingedient is 1.1-1.3:1.
2. anticancer honeyed bolus according to claim 1, it is characterised in that the drug ingedient by following parts by weight raw material group
Into：
15 parts of hydrolyzed pearl powder, 10 parts of Sculellaria barbata, 10 parts of subprostrate sophora, 8 parts of purslane, wolf's fang careless 6 parts, 4 parts of Toad Skin.
3. the preparation method of the anticancer honeyed bolus described in claim 1 or 2, it is characterised in that comprise the following steps：
（1）The preparation of hydrolyzed pearl powder：Pearl is milled, add water mixing, adjusts pH value, heating is stirred, dried, must hydrolyze
Pearl powder；
（2）Milling：Sculellaria barbata, subprostrate sophora, purslane, wolf's fang grass, Toad Skin are clayed into power respectively, 100 mesh sieves is crossed, obtains half
Lotus powder, subprostrate sophora powder, purslane powder, wolf's fang grass meal, Toad Skin powder；
（3）Refined honey：Honey is heated, when occur light red foam, hand-held viscosity it is stronger when, you can；
（4）Modulation：By step（1）Obtained hydrolyzed pearl powder and step（2）Obtained Sculellaria barbata powder, subprostrate sophora powder, purslane
Powder, wolf's fang grass meal, Toad Skin powder are well mixed, and add step（3）The honey of refining, is stirred continuously；
（5）By step（4）Medicine after modulation carries out rubbing, is then divided into pill, produces.
4. the preparation method of anticancer honeyed bolus according to claim 3, it is characterised in that the step（1）In, after milling
The weight ratio of pearl and water is 1:5-8, with vinegar acid for adjusting pH value to 4.5-4.8, heating-up temperature is 50-60 DEG C, and stir speed (S.S.) is
20-30rpm, mixing time 3-4h, drying temperature are 70-75 DEG C.
5. the preparation method of anticancer honeyed bolus according to claim 3, it is characterised in that the step（3）Middle honey heating
Temperature be 110-115 DEG C.
6. the preparation method of anticancer honeyed bolus according to claim 3, it is characterised in that the step（5）In aseptic condition
It is lower to carry out.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710181735.2A CN106974963A (en) | 2017-03-24 | 2017-03-24 | A kind of anticancer honeyed bolus and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710181735.2A CN106974963A (en) | 2017-03-24 | 2017-03-24 | A kind of anticancer honeyed bolus and preparation method thereof |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1100320A (en) * | 1994-03-10 | 1995-03-22 | 王申 | Dysphagia pills |
| CN1183290A (en) * | 1996-11-26 | 1998-06-03 | 孙黛娟 | Anticancer drug |
| CN101249235A (en) * | 2008-03-29 | 2008-08-27 | 李玉林 | Chinese medicine for curing esophagus cancer and method of preparing the same |
| CN102423438A (en) * | 2011-12-27 | 2012-04-25 | 峨眉山天梁星制药有限公司 | Anticancer double-prescription medicament and preparation method thereof |
-
2017
- 2017-03-24 CN CN201710181735.2A patent/CN106974963A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1100320A (en) * | 1994-03-10 | 1995-03-22 | 王申 | Dysphagia pills |
| CN1183290A (en) * | 1996-11-26 | 1998-06-03 | 孙黛娟 | Anticancer drug |
| CN101249235A (en) * | 2008-03-29 | 2008-08-27 | 李玉林 | Chinese medicine for curing esophagus cancer and method of preparing the same |
| CN102423438A (en) * | 2011-12-27 | 2012-04-25 | 峨眉山天梁星制药有限公司 | Anticancer double-prescription medicament and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 叶定江 等: "《中药炮制学辞典》", 30 June 2005, 上海科学技术出版社 * |
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Application publication date: 20170725 |