CN106955092A - A kind of measuring method and equipment of pulse distribution - Google Patents
A kind of measuring method and equipment of pulse distribution Download PDFInfo
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- CN106955092A CN106955092A CN201710211395.3A CN201710211395A CN106955092A CN 106955092 A CN106955092 A CN 106955092A CN 201710211395 A CN201710211395 A CN 201710211395A CN 106955092 A CN106955092 A CN 106955092A
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- pulse
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- artery site
- distribution information
- artery
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4854—Diagnosis based on concepts of traditional oriental medicine
Abstract
This application discloses the measuring method and equipment of a kind of pulse distribution, methods described includes：Speckle interference light path is built, wherein, the artery site of the beat pulse comprising tested organism in the speckle interference light path；According to the speckle interference light path, the pulse distributed intelligence of the artery site is determined, wherein, the pulse distributed intelligence includes：Pulse space distribution information and/or pulse Annual distribution information.According to the method and apparatus of the embodiment of the present application, the measurement being distributed to pulse can be realized, effectively objective pulse data is provided for clinical diagnosis.
Description
Technical field
The application is related to whole audience technical field of light detection, more particularly to the measuring method and equipment that a kind of pulse is distributed.
Background technology
Being felt the pulse in traditional Chinese medicine also known as feel the pulse, and refers to traditional Chinese physician by pressing the artery of patient to perceive beat pulse,
Pulse condition is recognized, and then is diagnosed the illness according to pulse condition.
Traditional Chinese physician recognizes pulse condition, is often analyzed in terms of arteries and veins position, rapid pulse, arteries and veins shape, arteries and veins gesture four.Arteries and veins position refers to beat pulse
The position shown and length, rapid pulse refer to the number of times and the rhythm and pace of moving things of beat pulse, and arteries and veins shape refers to the forms such as the width of beat pulse, and arteries and veins gesture refers to
The trend such as power, the smoothness of beat pulse.Pulse condition is the reflection to function of human body, different pulse condition all corresponding illness models
Enclose.
Human pulse is a kind of small unstable vibration of amplitude.Electronic sphygmograph of the prior art, for example：Electronic type
Electronic sphygmograph or photo-electric electronic sphygmograph, can only be measured, it is impossible to survey to the vibration frequency information (i.e. rapid pulse) of pulse
Measure other pulse informations in addition to the vibration frequency information of pulse.
The content of the invention
In view of this, the embodiment of the present application provides a kind of measuring method and equipment of pulse distribution, for solving existing skill
The technical problem of other pulse informations in addition to the vibration frequency information of pulse can not be measured in art, visitor is provided for clinical diagnosis
The pulse distributed data of sight.
The embodiment of the present application provides a kind of measuring method of pulse distribution, including：
Speckle interference light path is built, wherein, the dynamic of the beat pulse for being tested organism is included in the speckle interference light path
Arteries and veins position；
According to the speckle interference light path, the pulse distributed intelligence of the artery site is determined, wherein, the pulse distribution
Information includes：Pulse space distribution information and/or pulse Annual distribution information.
Alternatively, according to the speckle interference light path, the pulse space distribution information of the artery site is determined, including：
The first speckle pattern for the artery site is gathered at the first moment, and in the collection of the second moment for described
Second speckle pattern of artery site；
The corresponding first phase amount of first speckle pattern is determined, and determines corresponding second phase of second speckle pattern
Position amount；
According to the first phase amount and the second phase amount, arteries and veins of the artery site at second moment is determined
Fight space distribution information.
Alternatively, according to the speckle interference light path, the pulse Annual distribution information of the artery site is determined, including：
Several speckle patterns of collection for the artery site in preset duration；
It is determined that the corresponding multiple phase masses of described several speckle patterns；
According to the multiple phase mass, pulse Annual distribution letter of the artery site in the preset duration is determined
Breath.
Alternatively, the speckle interference light path is spatial carrier digital speckle interference light path, wherein, the spatial carrier number
Laser of the word speckle interference light path comprising satisfaction setting coherence length value, beam splitter, beam-expanding element, diaphragm, image-forming component
And imaging sensor, the spatial carrier digital speckle interference light path is built, including：
The laser launches laser；
The laser reflects via the beam splitter to be obtained and meets the reference light of set angle and be incident to the figure
As sensor；
The laser is transmitted through the beam-expanding element via the beam splitter, and the beam-expanding element is by the laser beam expanding
The artery site is illuminated after outgoing, reflecting obtained the first object light through the artery site is incident to the diaphragm, and via
The diaphragm is transmitted through the image-forming component, wherein, the diaphragm is used to cause that the spatial frequency satisfaction of first object light to be set
Determine scope；
The second object light that the image-forming component imaging is obtained is incident to described image sensor；
Second object light is interfered with the reference light on described image sensor surface.
Alternatively, methods described also includes：
According to the pulse space distribution information and/or the pulse Annual distribution information, the tested organism is analyzed
Health status.
The embodiment of the present application also provides a kind of measuring apparatus of pulse distribution, including：Speckle interference optical path unit and determination
Unit, wherein：
Speckle interference optical path unit, the artery site of the beat pulse for illuminating tested organism；
Determining unit, the pulse distributed intelligence for determining the artery site, wherein, the pulse distributed intelligence bag
Include：Pulse space distribution information and pulse Annual distribution information.
At least one above-mentioned technical scheme that the embodiment of the present application is used can reach following beneficial effect：
By the speckle interference light path for the artery site for building the beat pulse comprising tested organism, and then according to described
Speckle interference light path, determines the pulse space distribution information and/or pulse Annual distribution information of the artery site, realizes to arteries and veins
Fight the measurement of distribution, effectively objective pulse data is provided for clinical diagnosis.
Brief description of the drawings
Accompanying drawing described herein is used for providing further understanding of the present application, constitutes the part of the application, this Shen
Schematic description and description please is used to explain the application, does not constitute the improper restriction to the application.In the accompanying drawings：
A kind of schematic flow sheet of the measuring method for pulse distribution that Fig. 1 provides for the embodiment of the present application；
The light path schematic diagram for the spatial carrier digital speckle interference light path that Fig. 2 provides for the embodiment of the present application；
The schematic diagram of one width speckle pattern of the destination object that Fig. 3 (a) provides for the embodiment of the present application；
The schematic diagram of one width frequency spectrum profile of the destination object that Fig. 3 (b) provides for the embodiment of the present application；
Fig. 3 (c) for the filtered frequency spectrum of destination object that the embodiment of the present application is provided schematic diagram；
The schematic diagram of the deformation phase diagram for the destination object that Fig. 3 (d) provides for the embodiment of the present application；
A kind of structural representation of the measuring apparatus for pulse distribution that Fig. 4 provides for the embodiment of the present application.
Embodiment
In order to realize the purpose of the application, the embodiment of the present application provides the measuring method and equipment that a kind of pulse is distributed,
By the speckle interference light path for the artery site for building the beat pulse comprising tested organism, and then according to the speckle interference
Light path, determines the pulse space distribution information and/or pulse Annual distribution information of the artery site, realizes what pulse was distributed
Measurement, effectively objective pulse data is provided for clinical diagnosis.
Technical scheme is clearly and completely retouched with reference to the application specific embodiment and corresponding accompanying drawing
State.Obviously, described embodiment is only some embodiments of the present application, rather than whole embodiments.Based in the application
Embodiment, the every other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made,
Belong to the scope of the application protection.
Below in conjunction with accompanying drawing, the technical scheme that each embodiment of the application is provided is described in detail.
Embodiment 1
A kind of schematic flow sheet of the measuring method for pulse distribution that Fig. 1 provides for the embodiment of the present application.Methods described can
With as follows.
Step 11：Build speckle interference light path.
Wherein, the artery site of the beat pulse comprising tested organism in speckle interference light path.
In a step 11, the speckle interference light path of the artery site of the beat pulse comprising tested organism is built, to enter
The measurement that one step carries out pulse distribution according to the speckle interference light path is prepared.
Wherein, it is tested organism artery site and represents that the beat pulse of the tested organism is obvious, easy measuring point, example
Such as：The radial artery of the nearly wrist portion of human body, is not specifically limited here.
Alternatively, speckle interference light path is spatial carrier digital speckle interference light path.
Beat pulse is a kind of small unstable vibration of amplitude, belongs to dynamic deformation, spatial carrier digital speckle interference
Light path can be measured to the dynamic deformation of pulse, and then obtain the corresponding spatial distribution of pulse and Annual distribution.
Spatial carrier digital speckle interference light path is believed by the way that reference light and inclined light shaft set angle are produced into spatial carrier
Number.After the speckle pattern obtained to measurement implements Fourier transformation, obtain comprising destination object (the pulse jump of tested organism
Dynamic artery site) deformation data HFS and represent the low frequency part of bias light, due to the introducing of spatial carrier signal
The HFS in frequency spectrum is occurred frequency displacement, realize the separation with low frequency part, so including destination object deformation by extracting
The HFS of information and then interferometric phase is solved, finally according to the relation between interferometric phase and destination object deformation quantity, really
Set the goal the deformation quantity of object.
It should be noted that spatial carrier digital speckle interference light path can be the spatial light built in space environment
Road or the light path being integrated in measuring instrument, are not specifically limited here.
The light path schematic diagram for the spatial carrier digital speckle interference light path that Fig. 2 provides for the embodiment of the present application.
As shown in Fig. 2 alternatively, spatial carrier digital speckle interference light path includes the laser for meeting setting coherence length value
Device, beam splitter, beam-expanding element, diaphragm, image-forming component and imaging sensor, build the spatial carrier digital speckle interference light
Road, including：
Laser launches laser；
Laser reflects via beam splitter to be obtained and meets the reference light of set angle and be incident to imaging sensor；
Laser is transmitted through beam-expanding element via beam splitter, and beam-expanding element will illuminate artery portion after the laser beam expanding outgoing
Position, reflects the first obtained object light through artery site and is incident to diaphragm, and is transmitted through image-forming component via diaphragm, wherein, the light
Door screen is used to make it that the spatial frequency of first object light meets setting range；
The second object light that image-forming component imaging is obtained is incident to imaging sensor；
Second object light is interfered with reference light in image sensor surface.
Wherein, set angle (α) meets formula：
Wherein, λ represents that laser launches the wavelength of laser, fMRepresent the spatial frequency of the first object light, fPRepresent image sensing
The time sampling frequency of device.
It should be noted that setting coherence length value represents that the laser of laser emitting ensure that reference light and the second thing
Light is interfered, and the size of the setting coherence length value can be determined according to actual conditions, be not specifically limited here.
In the embodiment of the present application, the time sampling frequency of imaging sensor specifically takes on the basis of sample frequency is met
Value can be determined according to actual conditions, be not specifically limited here.
It should be noted that in order to according to spatial carrier digital speckle interference light path, determine the pulse of artery site
Distribution, the spatial frequency f of the first object lightMMeet setting range：
Because diaphragm is used to make it that the spatial frequency of the first object light meets setting range, therefore, the aperture size of the diaphragm
Meet：
Wherein, d represents the diaphragm to the distance of image-forming component.
Alternatively, beam splitter is adjustable light splitting plain film.
Beam splitter is in addition to it can use adjustable light splitting plain film, it would however also be possible to employ adjustable light splitting mirror, can also use
Other can carry out the optical element of light splitting, be not specifically limited here.
Alternatively, beam-expanding element is microcobjective.
Beam-expanding element is in addition to it can use the microcobjective, it would however also be possible to employ plano-concave lens, can also use it
The optical element that he can be expanded, is not specifically limited here.
Preferably, image-forming component is planoconvex spotlight.
Image-forming component is in addition to it can use planoconvex spotlight, it would however also be possible to employ industrial lens, can also use other energy
Enough optical elements being imaged, are not specifically limited here.
In the embodiment of the present application, the speckle interference light path except can using spatial carrier digital speckle interference light path it
Outside, 4+1 time-phase displacement digital speckle interference light paths can also be used, the speckle of dynamic deformation can also can be measured using other
Optical interference circuit, is not specifically limited here.
Step 12：According to speckle interference light path, the pulse distributed intelligence of the artery site is determined.
Wherein, pulse distributed intelligence includes：Pulse space distribution information and/or pulse Annual distribution information.
In step 12, according to the speckle interference light path built in step 11, it is determined that the beat pulse of tested organism
The pulse space distribution information and/or pulse Annual distribution information of artery site.
Alternatively, according to speckle interference light path, the pulse space distribution information of artery site is determined, specifically, the first step,
The first speckle pattern for artery site is gathered at the first moment, and is dissipated in the collection of the second moment for the second of artery site
Spot figure.
For example, by taking spatial carrier digital speckle interference light path as an example, being because image-forming component is imaged the second obtained object light
What is obtained afterwards is imaged to artery site, second object light is interfered with reference light in image sensor surface, therefore,
The interference speckle pattern (hereinafter referred to as speckle pattern) for the artery site can be collected by the imaging sensor.
Imaging sensor is directed to the first speckle pattern and second of artery site at the first moment and the collection of the second moment respectively
Speckle pattern.
Second step, determines the corresponding first phase amount of the first speckle pattern, and determine corresponding second phase of the second speckle pattern
Position amount.
3rd step, according to first phase amount and second phase amount, determines artery site in the pulse space at the second moment point
Cloth information.
The schematic diagram of first speckle pattern of the destination object that Fig. 3 (a) provides for the embodiment of the present application.
Still by taking above-mentioned spatial carrier digital speckle interference light path as an example, to destination object (for example：Artery site) it is corresponding
First speckle pattern (for example, Fig. 3 (a)) carries out Fourier transformation, obtains the corresponding frequency spectrum profile of the first speckle pattern, Fig. 3 (b)
The schematic diagram of the frequency spectrum profile of the destination object provided for the embodiment of the present application.
The corresponding spectrum distribution of first speckle pattern is：
I(fx)=FT [I (x)]=A (fx)+B(fx)+C(fx),
Wherein, I (fx) the corresponding spectrum distribution of the first speckle pattern is represented, I (x) represents the luminous intensity of destination object, A (fx)
With B (fx) represent two HFSs being conjugated, C (fx) represent low frequency part, fxFrequency domain coordinates are represented, x represents that the one-dimensional space is sat
Mark, symbol FT represents Fourier transform.
In frequency spectrum profile：
A(fx)=FT [O (x) R*(x)]；
B(fx)=FT [R (x) O*(x)]；
C(fx)=FT [| R (x) |2+|O(x)|2]。
Wherein, R (x) represents the luminous intensity of the object light of destination object, and O (x) represents the luminous intensity of reference light, and symbol * is represented
Conjugation.
Filtered by spectral window, obtain one of HFS A (fx), filter off other two portions of the spectrum B (fx) and
C(fx), Fig. 3 (c) for the filtered frequency spectrum of destination object that the embodiment of the present application is provided schematic diagram.
Inverse Fourier transform is carried out to frequency spectrum after filtering, according to following formula, the first phase containing destination object is obtained
The expression formula of amount：
Wherein, AIFTThe expression formula of the first phase amount containing destination object of expression,Represent the first phase of destination object
Amount, A (x) represents the intensity signal of interference light of the destination object when obtaining the first speckle pattern, and symbol IFT represents Fourier inversion
Change.
Similarly, for corresponding second speckle pattern of destination object, it again may be by performing above-mentioned Fourier transformation, filtering
Processing and the operation of inverse Fourier transform, obtain the expression formula of the second phase amount containing destination object：
Wherein, AIFT' represent the second phase amount containing destination object expression formula,Represent the second phase of destination object
Position amount, A'(x) intensity signal of interference light of the destination object when obtaining the second speckle pattern is represented, symbol IFT represents Fourier
Inverse transformation.
Obtaining the table of the expression formula of the first phase amount containing destination object and second phase amount containing destination object
Up to after formula, according to the expression of the expression formula of the first phase amount containing destination object and the second phase amount containing destination object
Formula, by following formula, obtains the deformation data of destination object.
Wherein, Im and Re represent imaginary part and real part respectively, and symbol * represents conjugation.
The schematic diagram of the deformation phase diagram for the destination object that Fig. 3 (d) provides for the embodiment of the present application.
According to the deformation data of destination object, space distribution information of the destination object at the second moment is determined, including：
According to the deformation data of destination object, determine that spatial distribution of the destination object at the second moment is believed by below equation
Breath：
Wherein,Represent the space distribution information of destination object, i.e. deformation of each position of destination object at the second moment
Distribution,The deformation data of destination object is represented,The sensitive vector of displacement is represented,kiArtery site is illuminated in expression
The unit vector in direction, koThe unit vector in the first object light direction is represented, λ represents that laser launches the wavelength of laser.
It should be noted that destination object represents the artery site of the beat pulse of tested organism, i.e., using above-mentioned note
The scheme of load, it is determined that the pulse space distribution information of the artery site of tested organism.
Alternatively, according to speckle interference light path, the pulse Annual distribution information of artery site is determined, specifically, the first step,
Several speckle patterns of collection for artery site in preset duration.
Imaging sensor gathers several speckle patterns for artery site in preset duration.
It should be noted that the quantity of several speckle patterns is relevant with preset duration, the time sampling frequency of imaging sensor.
For example：The time sampling frequency of imaging sensor is 75 frames/second, and preset duration was 10 seconds, in preset duration 10 seconds
The quantity of several speckle patterns inside collected is 750.
Second step, determines the corresponding multiple phase masses of several speckle patterns.
3rd, according to multiple phase masses, determine pulse Annual distribution information of the artery site in the preset duration.
Still by taking above-mentioned spatial carrier digital speckle interference light path as an example, by spatial carrier method, such as above-mentioned Fig. 3 (a), Fig. 3
(b) speckle pattern according to destination object recorded with Fig. 3 (c), determines the operation of the corresponding phase mass of speckle pattern, it is determined that for dynamic
The corresponding multiple phase masses of several speckle patterns that arteries and veins position is collected；And, by above-mentioned record according to first phase amount
With second phase amount, the operation of the deformation data of destination object is determined, two phases of arbitrary neighborhood in multiple phase masses
Amount, determines multiple pulse deformation datas of artery site.
For example, collecting 4 spoke speckle patterns for artery site A in preset duration, 4 width speckle patterns corresponding 4 are determined
Individual phase mass a, b, c and d.According to phase mass a and phase mass b, the first pulse deformation data of artery site is determinedAccording to
Phase mass b and phase mass c, determines the second pulse deformation data of artery siteAccording to phase mass c and phase mass d, it is determined that
3rd pulse deformation data of artery site
It should be noted that determining the method for the corresponding multiple phase masses of several speckle patterns, spatial carrier method can be used,
4+1 temporal phase-shifting methods can be used, the method that can also can measure dynamic deformation using other is not specifically limited here.
For example, when determining multiple phase masses using 4+1 temporal phase-shifting methods, first, by four-stepped switching policy collection for dynamic
The initial speckle pattern of 4 width at arteries and veins position；Secondly, several speckle patterns of collection for artery site in preset duration；Finally, according to
Any width and the initial speckle pattern of 4 width in several speckle patterns, passage time phase shift algorithm determine that several speckle patterns are corresponding
Multiple phase masses.
The deformation data according to destination object recorded by above-mentioned Fig. 3 (d), determines the side of the deformation distribution of destination object
Method, determines multiple pulse deformation distribution of artery site.
Still by taking above-mentioned artery site A as an example, according to the first pulse deformation data, determine that the first pulse deformation is distributed；According to
Second pulse deformation data, determines that the second pulse deformation is distributed；According to the 3rd pulse deformation data, the 3rd pulse deformation point is determined
Cloth.
First pulse deformation distribution, the second pulse deformation distribution and the 3rd pulse deformation distribution together constitute artery site
Pulse Annual distribution information in preset duration.
In the alternative embodiment of the application, methods described also includes：
According to the pulse space distribution information and/or the pulse Annual distribution information, the tested organism is analyzed
Health status.
According to the pulse space distribution information of the artery site of tested organism, the arteries and veins position of pulse can be obtained；According to quilt
The pulse Annual distribution information of the artery site of organism is surveyed, the rapid pulse of pulse can be obtained；The artery of comprehensive tested organism
The pulse space distribution information and pulse Annual distribution information at position, can obtain the arteries and veins shape and arteries and veins gesture of pulse.According to pulse
The pulse condition informations such as arteries and veins position, rapid pulse, arteries and veins shape, arteries and veins gesture, can analyze the health status of tested organism.
Technical scheme described in the embodiment of the present application, by the artery portion for building the beat pulse comprising tested organism
The speckle interference light path of position, and then according to the speckle interference light path, determine the pulse space distribution information of the artery site
And/or pulse Annual distribution information, the measurement being distributed to pulse is realized, effectively objective pulse data is provided for clinical diagnosis.
Embodiment 2
A kind of structural representation of the measuring apparatus for pulse deformation that Fig. 4 provides for the embodiment of the present application, equipment 400 is wrapped
Include：Speckle interference optical path unit 401 and determining unit 402, wherein：
Speckle interference optical path unit 401, the artery site of the beat pulse for illuminating tested organism；
Determining unit 402, the pulse distributed intelligence for determining artery site, wherein, pulse distributed intelligence includes：Pulse
Space distribution information and/or pulse Annual distribution information.
Optionally it is determined that unit 402 determines the pulse space distribution information of artery site, including：
The first speckle pattern for artery site is gathered at the first moment, and collection is directed to artery site at the second moment
The second speckle pattern；
The corresponding first phase amount of the first speckle pattern is determined, and determines the corresponding second phase amount of the second speckle pattern；
According to first phase amount and second phase amount, pulse space distribution information of the artery site at the second moment is determined.
Optionally it is determined that unit 402 determines the pulse Annual distribution information of artery site, including：
Several speckle patterns of collection for artery site in preset duration；
Determine the corresponding multiple phase masses of several speckle patterns；
According to multiple phase masses, pulse Annual distribution information of the artery site in preset duration is determined.
Alternatively, speckle interference optical path unit 401 is spatial carrier digital speckle interference optical path unit, wherein, the space
The laser for meeting setting coherence length value, beam splitter, beam-expanding element, light are included in carrier wave digital speckle interference optical path unit
Door screen, image-forming component and imaging sensor, wherein：
Laser launches laser；
Laser reflects via beam splitter to be obtained and meets the reference light of set angle and be incident to imaging sensor；
Laser is transmitted through beam-expanding element via beam splitter, and beam-expanding element will illuminate artery site after laser beam expanding outgoing,
The first obtained object light is reflected through artery site and is incident to diaphragm, and is transmitted through image-forming component via diaphragm, wherein, diaphragm is used for
So that the spatial frequency of the first object light meets setting range；
The second object light that image-forming component imaging is obtained is incident to imaging sensor；
Second object light is interfered with reference light in image sensor surface.
Alternatively, equipment 400 also includes：Analytic unit, wherein：
Analytic unit, for according to pulse space distribution information and/or pulse Annual distribution information, analysis to be tested organism
Health status.
The measuring apparatus being distributed according to the pulse, the speckle interference optical path unit is used for the arteries and veins for illuminating tested organism
Fight the artery site of bounce；The determining unit is used for the pulse space distribution information and/or pulse for determining the artery site
Annual distribution information, realizes the measurement being distributed to pulse, and effectively objective pulse data is provided for clinical diagnosis.
It should be understood by those skilled in the art that, embodiments of the invention can be provided as method, system or computer program
Product.Therefore, the present invention can be using the reality in terms of complete hardware embodiment, complete software embodiment or combination software and hardware
Apply the form of example.Moreover, the present invention can be used in one or more computers for wherein including computer usable program code
The computer program production that usable storage medium is implemented on (including but is not limited to magnetic disk storage, CD-ROM, optical memory etc.)
The form of product.
The present invention is the flow with reference to method according to embodiments of the present invention, equipment (system) and computer program product
Figure and/or block diagram are described.It should be understood that every one stream in flow chart and/or block diagram can be realized by computer program instructions
Journey and/or the flow in square frame and flow chart and/or block diagram and/or the combination of square frame.These computer programs can be provided
The processor of all-purpose computer, special-purpose computer, Embedded Processor or other programmable data processing devices is instructed to produce
A raw machine so that produced by the instruction of computer or the computing device of other programmable data processing devices for real
The device for the function of being specified in present one flow of flow chart or one square frame of multiple flows and/or block diagram or multiple square frames.
These computer program instructions, which may be alternatively stored in, can guide computer or other programmable data processing devices with spy
Determine in the computer-readable memory that mode works so that the instruction being stored in the computer-readable memory, which is produced, to be included referring to
Make the manufacture of device, the command device realize in one flow of flow chart or multiple flows and/or one square frame of block diagram or
The function of being specified in multiple square frames.
These computer program instructions can be also loaded into computer or other programmable data processing devices so that in meter
Series of operation steps is performed on calculation machine or other programmable devices to produce computer implemented processing, thus in computer or
The instruction performed on other programmable devices is provided for realizing in one flow of flow chart or multiple flows and/or block diagram one
The step of function of being specified in individual square frame or multiple square frames.
In a typical configuration, computing device includes one or more processors (CPU), input/output interface, net
Network interface and internal memory.
Internal memory potentially includes the volatile memory in computer-readable medium, random access memory (RAM) and/or
The forms such as Nonvolatile memory, such as read-only storage (ROM) or flash memory (flash RAM).Internal memory is computer-readable medium
Example.
Computer-readable medium includes permanent and non-permanent, removable and non-removable media can be by any method
Or technology realizes information Store.Information can be computer-readable instruction, data structure, the module of program or other data.
The example of the storage medium of computer includes, but are not limited to phase transition internal memory (PRAM), static RAM (SRAM), moved
State random access memory (DRAM), other kinds of random access memory (RAM), read-only storage (ROM), electric erasable
Programmable read only memory (EEPROM), fast flash memory bank or other memory techniques, read-only optical disc read-only storage (CD-ROM),
Digital versatile disc (DVD) or other optical storages, magnetic cassette tape, the storage of tape magnetic rigid disk or other magnetic storage apparatus
Or any other non-transmission medium, the information that can be accessed by a computing device available for storage.Define, calculate according to herein
Machine computer-readable recording medium does not include temporary computer readable media (transitory media), such as data-signal and carrier wave of modulation.
It should also be noted that, term " comprising ", "comprising" or its any other variant are intended to nonexcludability
Comprising so that process, method, commodity or equipment including a series of key elements are not only including those key elements, but also wrap
Include other key elements being not expressly set out, or also include for this process, method, commodity or equipment intrinsic want
Element.In the absence of more restrictions, the key element limited by sentence "including a ...", it is not excluded that wanted including described
Also there is other identical element in process, method, commodity or the equipment of element.
It will be understood by those skilled in the art that embodiments herein can be provided as method, system or computer program product.
Therefore, the application can be using the embodiment in terms of complete hardware embodiment, complete software embodiment or combination software and hardware
Form.Deposited moreover, the application can use to can use in one or more computers for wherein including computer usable program code
The shape for the computer program product that storage media is implemented on (including but is not limited to magnetic disk storage, CD-ROM, optical memory etc.)
Formula.
Embodiments herein is the foregoing is only, the application is not limited to.For those skilled in the art
For, the application can have various modifications and variations.It is all any modifications made within spirit herein and principle, equivalent
Replace, improve etc., it should be included within the scope of claims hereof.
Claims (10)
1. a kind of measuring method of pulse distribution, it is characterised in that including：
Speckle interference light path is built, wherein, the artery portion of the beat pulse comprising tested organism in the speckle interference light path
Position；
According to the speckle interference light path, the pulse distributed intelligence of the artery site is determined, wherein, the pulse distributed intelligence
Including：Pulse space distribution information and/or pulse Annual distribution information.
2. the method as described in claim 1, it is characterised in that according to the speckle interference light path, determine the artery site
Pulse space distribution information, including：
The first speckle pattern for the artery site is gathered at the first moment, and collection is directed to the artery at the second moment
Second speckle pattern at position；
The corresponding first phase amount of first speckle pattern is determined, and determines the corresponding second phase of second speckle pattern
Amount；
According to the first phase amount and the second phase amount, determine that the artery site is empty in the pulse at second moment
Between distributed intelligence.
3. the method as described in claim 1, it is characterised in that according to the speckle interference light path, determine the artery site
Pulse Annual distribution information, including：
Several speckle patterns of collection for the artery site in preset duration；
It is determined that the corresponding multiple phase masses of described several speckle patterns；
According to the multiple phase mass, pulse Annual distribution information of the artery site in the preset duration is determined.
4. the method as described in claim 1, it is characterised in that the speckle interference light path is spatial carrier digital speckle interference
Light path, wherein, the spatial carrier digital speckle interference light path includes laser, the light splitting member for meeting setting coherence length value
Part, beam-expanding element, diaphragm, image-forming component and imaging sensor, build the spatial carrier digital speckle interference light path, including：
The laser launches laser；
The laser via the beam splitter reflect obtain and meet set angle reference light be incident to described image pass
Sensor；
The laser is transmitted through the beam-expanding element via the beam splitter, and the beam-expanding element is by the laser beam expanding outgoing
After illuminate the artery site, reflecting obtained the first object light through the artery site is incident to the diaphragm, and via described
Diaphragm is transmitted through the image-forming component, wherein, the diaphragm is used to cause that the spatial frequency of first object light to meet setting model
Enclose；
The second object light that the image-forming component imaging is obtained is incident to described image sensor；
Second object light is interfered with the reference light on described image sensor surface.
5. the method as described in claim any one of 1-4, it is characterised in that methods described also includes：
According to the pulse space distribution information and/or the pulse Annual distribution information, the strong of the tested organism is analyzed
Health situation.
6. a kind of measuring apparatus of pulse distribution, it is characterised in that the equipment includes：Speckle interference optical path unit and determination are single
Member, wherein：
Speckle interference optical path unit, the artery site of the beat pulse for illuminating tested organism；
Determining unit, the pulse distributed intelligence for determining the artery site, wherein, the pulse distributed intelligence includes：Arteries and veins
Fight space distribution information and/or pulse Annual distribution information.
7. equipment as claimed in claim 6, it is characterised in that the determining unit determines the pulse space of the artery site
Distributed intelligence, including：
The first speckle pattern for the artery site is gathered at the first moment, and collection is directed to the artery at the second moment
Second speckle pattern at position；
The corresponding first phase amount of first speckle pattern is determined, and determines the corresponding second phase of second speckle pattern
Amount；
According to the first phase amount and the second phase amount, determine that the artery site is empty in the pulse at second moment
Between distributed intelligence.
8. equipment as claimed in claim 6, it is characterised in that the determining unit determines the pulse space of the artery site
Distributed intelligence, including：
Several speckle patterns of collection for the artery site in preset duration；
It is determined that the corresponding multiple phase masses of described several speckle patterns；
According to the multiple phase mass, Annual distribution information of the artery site in the preset duration is determined.
9. equipment as claimed in claim 6, it is characterised in that the speckle interference optical path unit is spatial carrier digital speckle
Optical interference circuit unit, wherein, the spatial carrier digital speckle interference optical path unit swashs comprising satisfaction setting coherence length value
Light device, beam splitter, beam-expanding element, diaphragm, image-forming component and imaging sensor, build the spatial carrier digital speckle interference
Light path, including：
The laser launches laser；
The laser via the beam splitter reflect obtain and meet set angle reference light be incident to described image pass
Sensor；
The laser is transmitted through the beam-expanding element via the beam splitter, and the beam-expanding element is by the laser beam expanding outgoing
After illuminate the artery site, reflecting obtained the first object light through the artery site is incident to the diaphragm, and via described
Diaphragm is transmitted through the image-forming component, wherein, the diaphragm is used to cause that the spatial frequency of first object light to meet setting model
Enclose；
The second object light that the image-forming component imaging is obtained is incident to described image sensor；
Second object light is interfered with the reference light on described image sensor surface.
10. the equipment as described in claim any one of 6-9, it is characterised in that the equipment also includes：Analytic unit, wherein：
Analytic unit, for according to the pulse space distribution information and/or the pulse Annual distribution information, analyzing the quilt
Survey the health status of organism.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107468222A (en) * | 2017-09-15 | 2017-12-15 | 王庆亚 | High-precision fast-response dynamic 3 D pulse detector |
| CN110101373A (en) * | 2019-06-14 | 2019-08-09 | 杭州电子科技大学 | A kind of pulses measure method and system based on laser speckle |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003139515A (en) * | 2001-11-02 | 2003-05-14 | Fukuoka Prefecture | Method for measuring absolute value of deformation quantity using speckle |
| CN101116087A (en) * | 2005-02-08 | 2008-01-30 | 皇家飞利浦电子股份有限公司 | Optical speckle pattern investigation |
| CN101784227A (en) * | 2007-07-06 | 2010-07-21 | 工业研究有限公司 | laser speckle imaging systems and methods |
| JP2010210399A (en) * | 2009-03-10 | 2010-09-24 | Saitama Univ | Minute displacement measuring method and apparatus |
| CN102144917A (en) * | 2006-05-24 | 2011-08-10 | 泰瑞连激光技术有限公司 | Optical vital sign detection method and measurement device |
| CN102221342A (en) * | 2011-04-02 | 2011-10-19 | 北京交通大学 | Method for measuring object deformation by time-domain multi-wavelength heterodyne speckle interference |
| WO2016029166A1 (en) * | 2014-08-22 | 2016-02-25 | Thomas Adrian Furness, Iii | Automated diagnosis based at least in part on pulse waveforms |
-
2017
- 2017-03-31 CN CN201710211395.3A patent/CN106955092B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003139515A (en) * | 2001-11-02 | 2003-05-14 | Fukuoka Prefecture | Method for measuring absolute value of deformation quantity using speckle |
| CN101116087A (en) * | 2005-02-08 | 2008-01-30 | 皇家飞利浦电子股份有限公司 | Optical speckle pattern investigation |
| CN102144917A (en) * | 2006-05-24 | 2011-08-10 | 泰瑞连激光技术有限公司 | Optical vital sign detection method and measurement device |
| CN101784227A (en) * | 2007-07-06 | 2010-07-21 | 工业研究有限公司 | laser speckle imaging systems and methods |
| JP2010210399A (en) * | 2009-03-10 | 2010-09-24 | Saitama Univ | Minute displacement measuring method and apparatus |
| CN102221342A (en) * | 2011-04-02 | 2011-10-19 | 北京交通大学 | Method for measuring object deformation by time-domain multi-wavelength heterodyne speckle interference |
| WO2016029166A1 (en) * | 2014-08-22 | 2016-02-25 | Thomas Adrian Furness, Iii | Automated diagnosis based at least in part on pulse waveforms |
Non-Patent Citations (1)
| Title |
|---|
| 刘凯等: "空间载波数字散斑干涉光路关键参数研究", 《自动化仪表》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107468222A (en) * | 2017-09-15 | 2017-12-15 | 王庆亚 | High-precision fast-response dynamic 3 D pulse detector |
| CN110101373A (en) * | 2019-06-14 | 2019-08-09 | 杭州电子科技大学 | A kind of pulses measure method and system based on laser speckle |
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|---|---|
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