CN106901739A - A kind of virtual reality stimulating apparatus for functional mri - Google Patents

A kind of virtual reality stimulating apparatus for functional mri Download PDF

Info

Publication number
CN106901739A
CN106901739A CN201710171641.7A CN201710171641A CN106901739A CN 106901739 A CN106901739 A CN 106901739A CN 201710171641 A CN201710171641 A CN 201710171641A CN 106901739 A CN106901739 A CN 106901739A
Authority
CN
China
Prior art keywords
component
presented
air
virtual
virtual reality
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201710171641.7A
Other languages
Chinese (zh)
Other versions
CN106901739B (en
Inventor
吴振洲
马昌玉
常严
杨晓冬
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suzhou Institute of Biomedical Engineering and Technology of CAS
Original Assignee
Suzhou Institute of Biomedical Engineering and Technology of CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suzhou Institute of Biomedical Engineering and Technology of CAS filed Critical Suzhou Institute of Biomedical Engineering and Technology of CAS
Priority to CN201710171641.7A priority Critical patent/CN106901739B/en
Publication of CN106901739A publication Critical patent/CN106901739A/en
Application granted granted Critical
Publication of CN106901739B publication Critical patent/CN106901739B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/4064Evaluating the brain
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F3/00Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
    • G06F3/01Input arrangements or combined input and output arrangements for interaction between user and computer
    • G06F3/011Arrangements for interaction with the human body, e.g. for user immersion in virtual reality

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Theoretical Computer Science (AREA)
  • Human Computer Interaction (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Psychology (AREA)
  • General Physics & Mathematics (AREA)
  • Dentistry (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Neurosurgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

The present invention discloses a kind of virtual reality stimulating apparatus for functional mri, including virtual vision is presented component, the sense of hearing and component, motion detection feedback component and operation control assembly is presented.The presentation of the virtual environment of the big angle of visual field can be effectively realized by the present apparatus, routing motion detection feedback component can make to carry out visual angle rotation, motion control etc. between subject and virtual environment to interact, there is provided a kind of as far as possible close to real virtual environment scene, it is hereby achieved that the brain activity fMRI experimental results being more nearly under true environment.

Description

A kind of virtual reality stimulating apparatus for functional mri
Technical field
The invention belongs to medical instruments field, and in particular to a kind of virtual reality for functional mri stimulates dress Put.
Background technology
Functional mri (functional magnetic resonance imaging, fMRI) is that one kind can be with For measuring the imaging technique of brain zone function activation, neurology and psychologic research are had been widely used at present.When people connects When receiving various environmental stimulis, corresponding brain area can be produced to activate in brain, and different environmental stimulis can produce it is different Activation brain area.FMRI is mainly used in detecting the position of each functional areas of intracerebral and the extent of reaction to various stimulations;May relate to The operation consent of brain domain, can be known a priori by whether corresponding functional areas can be damaged with fMRI technologies.Meanwhile, fMRI technologies It is one of most important method of non-damage evaluation and understanding brain function.
When the experiment of fMRI functional mris is carried out, it is necessary to design corresponding environmental stimuli source according to experiment purpose, Apply environmental stimuli by tested, continuous record environmental stimuli apply before (tranquillization state) (activated state) afterwards brain image, enter And process and obtain brain zone function activation figure corresponding with environmental stimuli, therefore fMRI stimulating apparatus be carry out nervous function into It is nervous function and psychological cognition providing a great convenience property of research, in fMRI systems as essential auxiliary equipment Occupied an important position in system.Visual stimulus and acoustic stimuli are two kinds of the most frequently used stimulation sources, and visual stimulus is in the mankind Neuro-sensory stimulate in account for the overwhelming majority, into brain information 70% above is by vision system receive, therefore Vision research is an importance of brain science.You Duo companies provide audio visual stimulating apparatus product at present, but Traditional visual stimulus device can only provide the pictorial stimulus in 2D planes, and stimulus modality is relatively single, it is impossible to provide trueer Real visual stimulus environment, so as to hardly result in the function activation image of mankind's brain area in true environment, obtained by making FMRI results of study have certain limitation.
The content of the invention
In order to solve the above-mentioned technical problem, the present invention proposes a kind of virtual reality for functional mri and stimulates Device, VR virtual realities (virtual reality) technology is combined with fMRI, is applied to the research of mankind's brain function.
In order to achieve the above object, technical scheme is as follows:
A kind of virtual reality stimulating apparatus for functional mri, including:Virtual vision present component, for for Human body provides virtual vision scene;The sense of hearing is presented component, for providing sense of hearing audio for human body;Motion detection feedback component, uses Detected in the motion state to human body, and form feedback information and pass to operation control assembly;Operation control assembly, operation The input of control assembly is connected with motion detection feedback component, receives feedback information, runs the output end difference of control assembly Component is presented with virtual vision and the sense of hearing is presented component and is connected, visual stimulus signal is provided for virtual vision is presented component, to listen Feel that component is presented provides acoustic stimuli signal;Virtual vision is presented component, the sense of hearing and component and motion detection feedback component is presented It is arranged in magnet bore, it is interior that magnet bore is arranged at magnet, between operation control assembly is arranged at external equipment.
A kind of virtual reality stimulating apparatus for functional mri of the invention, including virtual vision presentation component, The sense of hearing is presented component, motion detection feedback component and operation control assembly.Operation control assembly is produced for generating virtual reality The visual stimulus signal and acoustic stimuli signal of scene, wherein visual stimulus signal are by being transferred to up to virtual vision presentation group Part, in the immersion visual scene of the tested big angles of visual field of 3D of generation at the moment;Visual stimulus signal reaches the sense of hearing and device is presented, in quilt Examination ear produces high-quality auditory effect, so as to realize that reality environment stimulates the presentation at tested end;Motion detection is fed back Component receives the feedback information that subject provides, such as:Hand exercise information, and be passed back to run control assembly, run control group Part carries out immediate updating, so that tested by analyzing feedback information to being presented on the reality environment stimulation before being tested Person can carry out depth between reality environment and interact.
A kind of virtual reality stimulating apparatus for functional mri of the invention, it is possible to achieve various User Defineds Virtual reality scenario tested end presentation, while tested possess good interactive function, Neng Gouman and virtual environment between The requirement of the more fMRI experimental designs of foot.
On the basis of above-mentioned technical proposal, following improvement can be also done:
Used as preferred scheme, the sense of hearing is presented component and motion detection feedback component and is turned with for photoelectricity by optical fiber respectively The converter connection changed, converter is connected through waveguide plate by connection cable with operation control assembly;
Virtual vision is presented component and is connected with operation control assembly through waveguide plate by shielded cable;
Between converter is arranged at magnet, between waveguide plate is arranged between magnet between external equipment.
Using above-mentioned preferred scheme, it is ensured that the effectiveness between each several part, it is ensured that obtain the true of experimental result Real validity.
Used as preferred scheme, virtual vision is presented component to be included:Eyeshade framework and the left side being arranged in eyeshade framework Component and right presentation component is presented, left presentation component and right presentation component include respectively:For showing virtual vision stimulating image OLED screen curtain and be arranged at OLED screen curtain before VR eyepieces, OLED screen curtain be coaxially disposed with VR eyepieces.
Using above-mentioned preferred scheme so that subject can observe directly what is presented on OLED screen curtain by VR eyepieces Virtual vision stimulating image, obtains optimal virtual vision effect.
Used as preferred scheme, OLED screen curtain and VR eyepieces are arranged in faraday cup, and near VR on faraday cup Eyepiece side is provided with metal grill shielding observation window.
Using above-mentioned preferred scheme, the electricity of visual transmission electric signal, OLED screen curtain and magnetic resonance imaging equipment is realized Magnetic screen, it is to avoid virtual vision is presented interfering between device and magnetic resonance imaging equipment.
As preferred scheme, it is provided with eyeshade framework between for adjusting distance between left and right presentation component first The second spacing adjusting part away from adjusting part and for adjusting distance between VR eyepieces and subject's eyes.
Using above-mentioned preferred scheme, distance between the left and right presentation component of the first spacing adjusting part regulation, to adapt to not With the distance between subject two.Second spacing adjusting part adjusts distance between VR eyepieces and subject's eyes, to adapt to The eye diopter of different subjects, so that subject is able to observe that most clearly virtual reality scenario.
Used as preferred scheme, the sense of hearing is presented component includes that earmuff framework and the audio being arranged in earmuff framework occur Part, earmuff framework is connected with eyeshade framework.
Using above-mentioned preferred scheme, earmuff framework is integrated with eyeshade framework, improve standby integrated level, realized Integrated VR virtual realities helmet.
Used as preferred scheme, eyeshade framework includes frame body and is arranged to expand outwardly extension on frame body Tubaeform cladding flange, elastic layer and flexible layer are sequentially provided with the inner surface of cladding flange, in elastic layer and soft Property layer between be provided with air chamber, the airflow hole that air chamber passes through to be arranged on cladding flange is connected with outside air equipment.
Using above-mentioned preferred scheme, the laminating degree that virtual vision is presented component and subject can be effectively improved, make by Examination person isolates with reality scene, only it is observed that virtual vision is presented the virtual reality scenario represented in device, so as to obtain more Plus real immersion virtual vision effect.
Used as preferred scheme, outside air equipment is connected by air-flow size adjusting device with airflow hole, air-flow size Adjusting means includes:Air-flow seat, first through hole is provided with air-flow seat, and the slip of regular polygon is provided with the outside of first through hole Groove;Guide holder, is arranged at the side of air-flow seat, and the second through hole corresponding with first through hole is provided with guide holder, is being oriented to Multiple gathering sills are provided with the outside of upper second through hole of seat;Multiple catch, are arranged between air-flow seat and guide holder, in catch just Anti- opposing sides is respectively equipped with the first protuberance and the second protuberance, and the first protuberance is stretched into sliding recess, the second protuberance Stretch into gathering sill;Drive device, is connected with air-flow seat and guide holder respectively, and drive device drives air-flow seat and guide holder to turn It is dynamic, change the position of catch, so as to change the exposed size of first through hole and the second through hole.
Using above-mentioned preferred scheme, outside air equipment can be blown and pumping action, and air-flow size adjustment Device can effectively adjust the exposed size of first through hole and the second through hole, so that air-flow size is adjusted, to the sky in air chamber The number of Gas content and the speed of change are adjusted.And the air-flow size adjusting device of disclosure of the invention can be adjusted quickly The exposed size of through hole, low noise, low-power, cost is small.
As preferred scheme, be provided with photosensitive sensor and/or pressure sensor on flexible layer, photosensitive sensor and/ Or pressure sensor is connected with air-flow size adjusting device.
Using above-mentioned preferred scheme, virtual vision presentation group is detected by photosensitive sensor and/or pressure sensor Part and the laminating degree of subject, so as to preferably adjust air-flow size adjusting device, make subject isolate with reality scene, improve The effect of experiment.
As preferred scheme, multiple separation layers, separation layer and flexible layer are provided near the side of air chamber in flexible layer Between form inner chamber, one, two or more balls are provided with the inner chamber.
Using above-mentioned preferred scheme, ball can effectively massage subject's eye, the comfort level that raising is worn, and multiple Inner chamber can be distributed in key point, and due to there is ball to be aided at key point, virtual vision is presented component and subject Laminating degree is more preferable.
Brief description of the drawings
Fig. 1 is that the virtual reality stimulating apparatus framework for functional mri provided in an embodiment of the present invention is illustrated Figure.
Fig. 2 is the block schematic illustration that virtual vision provided in an embodiment of the present invention is presented component.
Fig. 3 is that virtual vision provided in an embodiment of the present invention is presented component and the sense of hearing is presented the structural representation of component.
Fig. 4 is that virtual vision provided in an embodiment of the present invention is presented component and the inside partial structurtes of sense of hearing presentation component are shown It is intended to.
Fig. 5 is that virtual vision provided in an embodiment of the present invention is presented component and the sense of hearing is presented the top view of component.
Fig. 6 is the block schematic illustration of motion detection feedback component provided in an embodiment of the present invention.
Fig. 7 is one of partial sectional view of elastic layer provided in an embodiment of the present invention, flexible layer and air chamber.
Fig. 8 is the structural representation of air-flow seat provided in an embodiment of the present invention.
Fig. 9 is the structural representation of air-flow seat provided in an embodiment of the present invention and catch.
Figure 10 is the structural representation of guide holder provided in an embodiment of the present invention.
Figure 11 is the two of the partial sectional view of elastic layer provided in an embodiment of the present invention, flexible layer and air chamber.
Wherein:Between 101 magnets, 102 equipment rooms, 103 operation rooms, 104 magnet bores, 111 virtual visions present component, 112 The sense of hearing is presented component, 113 motion detection feedback components, 114 operation control assemblies, 120 waveguide plates, 121 shielded cables, 122 light Fibre, 123 optical fiber, 124 converters, 125 connection cables, 201OLED screens, 202VR eyepieces, 203 faraday cups, 204 human eyes, 205HDMI ports, 301 eyeshade frameworks, 3011 frame bodies, 3012 cladding flange, 302 metal grills shielding observation window, 303 the One spacing adjusting part, 304 second spacing adjusting parts, 401 trackballs, 402 button handles, 403 gloves for game, 411RS232 Port, 412USB ports, 501 elastic layers, 502 flexible layers, 503 air chambers, 504 separation layers, 505 inner chambers, 506 balls, 601 gas Stream seat, 602 first through hole, 603 sliding recess, 604 guide holders, 605 second through holes, 606 gathering sills, 607 catch, 608 first Protuberance, 609 second protuberances.
Specific embodiment
The preferred embodiment that the invention will now be described in detail with reference to the accompanying drawings.
In order to reach the purpose of the present invention, wherein the one of a kind of virtual reality stimulating apparatus for functional mri In a little embodiments,
As shown in figure 1, a kind of virtual reality stimulating apparatus for functional mri include virtual vision presentation group The part 111, sense of hearing is presented component 112, motion detection feedback component 113 and operation control assembly 114.
Virtual vision is presented component 111 to be used to provide virtual vision scene for human body;The sense of hearing is presented component 112 to be used to be people Body provides sense of hearing audio;Motion detection feedback component 113 is used to detect the motion state of human body, and forms feedback information Pass to operation control assembly 114;The input for running control assembly 114 is connected with motion detection feedback component 113, receives anti- Feedforward information, the output end for running control assembly 114 is connected with virtual vision presentation component 111 and sense of hearing presentation component 112 respectively, Visual stimulus signal is provided for virtual vision is presented component 111, is that the sense of hearing is presented the offer acoustic stimuli signal of component 112.
Virtual vision is presented component 111, sense of hearing presentation component 112 and motion detection feedback component 113 is arranged at magnet In chamber 104, for being tested in fMRI in be worn on corresponding site with tested, magnet bore 104 is arranged in 101 between magnet. Wherein operation control assembly 114 is placed in the operation room 103 between external equipment;Magnet bore 104 is located between magnet in 101.It is empty Intend vision presentation component 111 to be connected with operation control assembly 114 by shielded cable 121, the sense of hearing is presented component 112, motion Detection feedback component 113 is connected to converter 124 by optical fiber 122,123 respectively, then is controlled with operation by connection cable 125 Component 114 is connected, and converter 124 is used to realize opto-electronic conversion.Shielded cable 121 and connection cable 125 are by between magnet The waveguide plate 120 set between equipment room 102 between 101 and external equipment, through equipment room 102, is ultimately connected to operation control The corresponding port of component processed 114.It is worth noting that, magnet bore 104 can be a large-scale magnet, and 101 it is between magnet Include between shielding house, external equipment for the equipment room 102 of storage equipment and the operation room 103 for operating, naturally it is also possible to It is a room or multiple rooms, it can be adjusted according to specific circumstances.
What is transmitted in shielded cable 121 and connection cable 125 is electric signal, and what is transmitted in optical fiber 122,123 is light Signal.In order to avoid converter 124 and connection cable 125 produce interference to MR imaging apparatus, converter 124 is placed on As far as possible away from the position of magnet bore 104 in 101 between magnet.
Operation control assembly 114 is equipped with the special operation software of set VR virtual reality stimulating apparatus, can support to use Family is self-defined, generates the video and audio stimulation signal of different virtual reality scenarios, and the fMRI experiments for meeting different set Meter is required.Wherein visual stimulus signal reaches virtual vision and component 111 is presented by shielded cable 121, is produced before subject The immersion visual scene of the big angles of visual field of raw 3D;Acoustic stimuli signal reaches sense of hearing presentation group by converter 124 and optical fiber 122 Part 112, high-quality auditory effect is produced in subject ear, so as to realize that reality environment stimulates the presentation at tested end; Motion detection feedback component 113 receives the feedback information that subject provides, such as:Hand exercise action message, and by optical fiber 123 It is passed back to run control assembly 114 with converter 124, operation control assembly 114 is tested to being presented on by analyzing feedback information Preceding virtual environment stimulates carries out immediate updating, is interacted so that being tested and depth being carried out between reality environment.
As shown in Fig. 2 virtual vision is presented the block schematic illustration of component 111, for will run what control assembly 114 was generated Visual stimulus signal is presented on subject at the moment, makes subject it was observed that virtual reality scenario.Virtual vision is presented component to be included: Eyeshade framework 301 and the left presentation component and right presentation component that are arranged in eyeshade framework 301, left presentation component and right presentation Component includes respectively:For the VR for showing the OLED screen curtain 201 of virtual vision stimulating image and be arranged at before OLED screen curtain 201 Eyepiece 202, OLED screen curtain 201 is coaxially disposed with VR eyepieces 202.
High-definition virtual visual effect true to nature is observed to make to be tested, preferably video is shown with two pieces of OLED screens curtains 201 Stimulus signal, the image for producing two width different is tested eyes 204 by VR eyepieces 202, can observe directly OLED screen curtain The image shown on 201.It is preferred that single OLED screen curtain resolution ratio is 1080 × 1200, so as to reach 2160 × 1200 combination point Resolution, dynamic refresh rate is more than 85Hz.
Interference is produced in order to avoid the OLED screen 201 pairs of MR imaging apparatus of curtain, it is necessary to by OLED screen curtain 201 and VR eyepieces 202 are placed in faraday cup 203, realize the electromagnetic shielding of OLED screen curtain 201.
The shielded cable 121 of OLED screen curtain 201 passes through waveguide plate 120, and operation room 103, connection are reached by equipment room 102 To the HDMI ports 205 for running control assembly 114, video electrical signal is received.
As shown in figure 3, component 111 is presented for virtual vision and the sense of hearing is presented the structural representation of component, virtual vision is presented Component 111 makes subject isolate with reality scene using the design of wear-type eyeshade, only it is observed that virtual vision is presented component The virtual reality scenario represented in 111, so as to obtain more real immersion virtual vision effect.
Virtual vision is presented component 111 and support internal structure is fixed using eyeshade framework 301.
The sense of hearing is presented component 112 includes that earmuff framework and the audio being arranged in earmuff framework occur part, earmuff framework It is connected with eyeshade framework 301.
Generally, it is two modules of autonomous working that virtual vision is presented component 111 and the sense of hearing and component 112 is presented, but this Shen Please earmuff framework is integrated with eyeshade framework, standby integrated level is improved, integration VR virtual reality helmets are realized.
As shown in Figures 4 and 5, virtual vision is presented component and the sense of hearing is presented the inside partial structural diagram of component.In eye Two faraday cups 203 are provided with cover framework 301, and (faraday cup for being located at right side in Fig. 4 is not shown, to show internal junction Structure), one piece of VR eyepiece 202 and one piece of OLED screen curtain 201 are respectively provided with each faraday cup 203, shielded cable 121 passes through eye Cover framework 301 and faraday cup 203, are connected with OLED screen curtain 201, transmit video electrical signal.Every piece of OLED screen curtain 201 and right Relative position between the VR eyepieces 202 answered is fixed, and in coaxially arranged;Faraday cup 203 is near subject's eye Side is provided with metal grill shielding observation window 302, tested left and right two is respectively observed by VR eyepieces 202 The different visual stimulus image of two width of display on OLED screen curtain 201, so that it was observed that the immersion of the big angles of visual field of 3D is virtually existing Real field scape.VR eyepieces 202 preferably use Fresnel Lenses, more frivolous compared to common eyeglass.
Be provided with eyeshade framework 301 for adjust it is left and right presentation component between distance the first spacing adjusting part 303 And for adjusting the second spacing adjusting part 304 of distance between VR eyepieces and subject's eyes.First spacing adjusting part Distance between the left and right presentation component of 303 regulations, to adapt to the distance between different subjects two.Second spacing adjusting part Distance between 304 regulation VR eyepieces and subject's eyes, to adapt to the eye diopter of different subjects, so that subject's energy It is enough to observe most clearly virtual reality scenario.
The sense of hearing is presented component 112 and mainly, without magnetic earphone, realizes that acoustic stimuli are believed by using the special optical fiber type of magnetic resonance Number tested end presentation, while magnetic compatibility condition is met, with good noise shielding effect.
The connecting line that the sense of hearing is presented component 112 passes through waveguide plate 120, operation room 103 is reached by equipment room 102, with fortune Row control assembly 114 is connected, and is mainly used to that the various EAXs in virtual environment are presented, and refer to from extraneous voice Order.
Because the head fixation being tested in fMRI experimentations cannot be moved, therefore cannot carry out moving instead using head Feedback operation, therefore the hand that motion detection feedback component 113 is arranged at subject is realized feedback function by the application.
Shown in Fig. 6 be motion detection feedback component 113 block schematic illustration, main movement detection feedback component 113 wrap Include trackball 401, button handle 402 and gloves for game 403 meet different fMRI experiment scene design requirements.Wherein chase after Track ball 401 can be used to complete visual angle rotation, the interactive action of position movement in reality environment, and button handle 402 can be with For completing the interactive action such as button feedback in reality environment, a number of position is included in gloves for game 403 Sensor, can accurately perceive the action of tested hand, can be used in hand exercise in finer reality environment Feedback, such as shoegaze, drive vehicle, the scene such as operating instrument equipment.
Trackball 401, button handle 402 and gloves for game 403 are designed using magnetic resonance compatible, without any magnetic portion Part, will not be interfered to fMRI imagings, and by optical fiber 123 be connected to converter 124 respectively, and converter 124 will be received Fiber-optic signal carry out opto-electronic conversion, then waveguide plate 120 is passed through by connection cable 125, by equipment room 102, be finally reached The RS232 ports 411 of the operation control assembly 114 in operation room 103 or USB port 412, the movable information that will be detected are anti- Feed and run control assembly 114.
Interference being produced in order to avoid converter 124, it is necessary to converter 124 is placed on into magnet to magnetic resonance equipment work Away from the position of magnet bore 104 in 101.
Operation control assembly 114 is equipped with the special operation software of set VR virtual reality stimulating apparatus, runs control group Part 114 receives the feedback information of the subject that motion detection feedback component 113 feeds back to, and is analyzed, to be presented on by Examination person's virtual reality video at the moment and audio carry out immediate updating, realize interacting work(between subject and reality environment Energy.
A kind of virtual reality stimulating apparatus for functional mri of the invention can realize the void of the big angles of visual field of 3D Near-ring border is presented, and routing motion detection means can make to be tested carries out the friendship such as visual angle rotation, motion control and virtual environment between Mutually.The present invention proposes a kind of research that VR virtual reality technologies are used for mankind's brain function with the mode that fMRI is combined, and carries For more real virtual environment interactive experience, so as to obtain as far as possible close to the mankind in the different special scenes under true environment Brain zone function activity distribution result.
As shown in fig. 7, in order to further optimize implementation result of the invention, in other implementation method, remaining Feature technology is identical, and difference is that eyeshade framework 301 includes frame body 3011 and is arranged on frame body 3011 The tubaeform cladding flange 3012 of extension is expanded outwardly, elastic layer is sequentially provided with the inner surface of cladding flange 3012 501 and flexible layer 502, air chamber 503 is provided between elastic layer 501 and flexible layer 502, air chamber 503 is by being arranged at Airflow hole (not shown) on cladding flange 3012 is connected with outside air equipment (not shown).
Using above-mentioned preferred scheme, the laminating degree that virtual vision is presented component 111 and subject can be effectively improved, made Subject isolates with reality scene, only it is observed that virtual vision is presented the virtual reality scenario represented in device, so as to obtain More real immersion virtual vision effect.
As seen in figs. 8-10, further, outside air equipment is connected by air-flow size adjusting device with airflow hole, air-flow Size adjusting device includes:Air-flow seat 601, first through hole 602 is provided with air-flow seat 601, is set in the outside of first through hole 602 There is the sliding recess 603 of regular polygon;Guide holder 604, is arranged at the side of air-flow seat 601, is provided with guide holder 604 and the The second corresponding through hole 605 of one through hole 602, the outside of second through hole 605 is provided with multiple gathering sills 606 on guide holder 604;It is many Individual catch 607, is arranged between air-flow seat 601 and guide holder 604, and first is respectively equipped with the positive and negative opposing sides of catch 607 The (not shown) of protuberance 608 and the second protuberance 609, the first protuberance 608 are stretched into sliding recess 603, the second protrusion Stretch into gathering sill 606 in portion 509;Drive device (not shown), is connected with air-flow seat 601 and guide holder 604 respectively, drives Device drives air-flow seat 601 and guide holder 604 to rotate, and changes the position of catch 607, so as to change first through hole 602 and second The exposed size of through hole 605.
Using above-mentioned preferred scheme, outside air equipment can be blown and pumping action, air-flow seat 601 and be oriented to Seat 604 is rotated such that it is able to the exposed size of the effectively regulation through hole 605 of first through hole 602 and second, so that air-flow size is adjusted, The speed of number and change to the air content in air chamber 503 is adjusted.And the air-flow size adjustment of disclosure of the invention Device can quickly adjust the exposed size of the through hole 605 of first through hole 602 and second, and low noise, low-power, cost is small, can Effectively to adjust the air content in air chamber 503, it is ensured that virtual vision is presented the laminating degree of component 111 and subject.
In order to further optimize implementation result of the invention, in other implementation method, remaining feature technology phase Together, difference is that photosensitive sensor and/or pressure sensor, photosensitive sensor and/or pressure are provided with flexible layer 502 Force snesor is connected with air-flow size adjusting device.
Further, void is detected by photosensitive sensor (not shown) and/or pressure sensor (not shown) Intend the laminating degree that vision is presented component 111 and subject, so as to preferably adjust air-flow size adjusting device, make subject and show Real field scape is isolated, and improves the effect of experiment.
As shown in figure 11, in order to further optimize implementation result of the invention, in other implementation method, remaining Feature technology is identical, and difference is to be provided with multiple separation layers 504 near the side of air chamber 503 in flexible layer 502, every Inner chamber 505 is formed between absciss layer 504 and flexible layer 502, one, two or more balls are provided with the inner chamber 505 506。
Using above-mentioned preferred scheme, ball 506 can effectively massage subject's eye, improve the comfort level worn, and Multiple inner chambers 505 can be distributed in key point, and due to there is ball 506 to be aided at key point, virtual vision is presented component 111 and subject laminating degree it is more preferable.
The above is only the preferred embodiment of the present invention, it is noted that for the person of ordinary skill of the art, Without departing from the concept of the premise of the invention, various modifications and improvements can be made, these belong to guarantor of the invention Shield scope.

Claims (10)

1. a kind of virtual reality stimulating apparatus for functional mri, it is characterised in that including:
Virtual vision is presented component, for providing virtual vision scene for human body;
The sense of hearing is presented component, for providing sense of hearing audio for human body;
Motion detection feedback component, detects for the motion state to human body, and formed feedback information pass to operation control Component processed;
Operation control assembly, the input of the operation control assembly is connected with the motion detection feedback component, receives described Feedback information, component is presented with the virtual vision respectively for the output end of the operation control assembly and the sense of hearing is presented component Connection, visual stimulus signal is provided for the virtual vision is presented component, and acoustic stimuli letter is provided for the sense of hearing is presented component Number;
The virtual vision is presented component, sense of hearing presentation component and the motion detection feedback component and is arranged at magnet bore Interior, it is interior that the magnet bore is arranged at magnet, between the operation control assembly is arranged at external equipment.
2. virtual reality stimulating apparatus for functional mri according to claim 1, it is characterised in that described The sense of hearing is presented component and the motion detection feedback component and is connected with the converter for opto-electronic conversion by optical fiber respectively, described Converter is connected through waveguide plate by connection cable with the operation control assembly;
The virtual vision is presented component and is connected with the operation control assembly through the waveguide plate by shielded cable;
Between the converter is arranged at the magnet, the waveguide plate is arranged between the magnet between the external equipment it Between.
3. virtual reality stimulating apparatus for functional mri according to claim 1 and 2, it is characterised in that The virtual vision is presented component to be included:Eyeshade framework and the left presentation component and the right presentation that are arranged in the eyeshade framework Component, the left presentation component and the right presentation component include respectively:OLED screen for showing virtual vision stimulating image Curtain and the VR eyepieces being arranged at before the OLED screen curtain, the OLED screen curtain are coaxially disposed with the VR eyepieces.
4. virtual reality stimulating apparatus for functional mri according to claim 3, it is characterised in that described OLED screen curtain and the VR eyepieces are arranged in faraday cup, and are provided near the VR eyepieces side on the faraday cup Metal grill shields observation window.
5. virtual reality stimulating apparatus for functional mri according to claim 4, it is characterised in that in institute State eyeshade framework be provided with for adjust it is left and right presentation component between distance the first spacing adjusting part and for adjusting State the second spacing adjusting part of distance between VR eyepieces and subject's eyes.
6. virtual reality stimulating apparatus for functional mri according to claim 5, it is characterised in that described The sense of hearing is presented component includes that earmuff framework and the audio being arranged in the earmuff framework occur part, the earmuff framework and institute State the connection of eyeshade framework.
7. virtual reality stimulating apparatus for functional mri according to claim 6, it is characterised in that described Eyeshade framework includes frame body and is arranged on frame body the tubaeform cladding flange for expanding outwardly extension, described Elastic layer and flexible layer are sequentially provided with the inner surface for coating flange, are provided between the elastic layer and the flexible layer Air chamber, the air chamber is connected by the airflow hole being arranged on the cladding flange with outside air equipment.
8. virtual reality stimulating apparatus for functional mri according to claim 7, it is characterised in that described Outside air equipment is connected by air-flow size adjusting device with the airflow hole, and the air-flow size adjusting device includes:
Air-flow seat, first through hole is provided with air-flow seat, and the slip of regular polygon is provided with the outside of the first through hole Groove;
Guide holder, is arranged at the side of the air-flow seat, and corresponding with the first through hole second is provided with the guide holder Through hole, multiple gathering sills are provided with the outside of the second through hole on the guide holder;
Multiple catch, are arranged between the air-flow seat and the guide holder, are set respectively in the positive and negative opposing sides of the catch There are the first protuberance and the second protuberance, first protuberance is stretched into the sliding recess, and second protuberance is stretched into In the gathering sill;
Drive device, is connected with air-flow seat and the guide holder respectively, and the drive device drives the air-flow seat and institute Guide holder rotation is stated, changes the position of the catch, so as to change the exposed size of the first through hole and second through hole.
9. virtual reality stimulating apparatus for functional mri according to claim 8, it is characterised in that in institute State flexible layer and be provided with photosensitive sensor and/or pressure sensor, the photosensitive sensor and/or the pressure sensor and institute State the connection of air-flow size adjusting device.
10. virtual reality stimulating apparatus for functional mri according to claim 9, it is characterised in that The flexible layer is provided with multiple separation layers near the side of the air chamber, forms interior between the separation layer and the flexible layer Chamber, is provided with one, two or more balls in the inner chamber.
CN201710171641.7A 2017-03-21 2017-03-21 Virtual reality stimulation device for functional magnetic resonance imaging Active CN106901739B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710171641.7A CN106901739B (en) 2017-03-21 2017-03-21 Virtual reality stimulation device for functional magnetic resonance imaging

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710171641.7A CN106901739B (en) 2017-03-21 2017-03-21 Virtual reality stimulation device for functional magnetic resonance imaging

Publications (2)

Publication Number Publication Date
CN106901739A true CN106901739A (en) 2017-06-30
CN106901739B CN106901739B (en) 2020-09-15

Family

ID=59194579

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710171641.7A Active CN106901739B (en) 2017-03-21 2017-03-21 Virtual reality stimulation device for functional magnetic resonance imaging

Country Status (1)

Country Link
CN (1) CN106901739B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107822635A (en) * 2017-11-27 2018-03-23 佛山市恒爱网络科技有限公司 Magnetic resonance imaging stimulates machine
CN108874157A (en) * 2018-09-07 2018-11-23 广州医科大学附属肿瘤医院 A kind of VR equipment and its virtual reality exchange method suitable for MRI
CN110192861A (en) * 2019-06-14 2019-09-03 广州医科大学附属肿瘤医院 A kind of intelligence auxiliary brain function real-time detecting system
CN113407024A (en) * 2021-05-25 2021-09-17 四川大学 Evidence display and switching method and device for court trial virtual reality environment
CN114203054A (en) * 2022-01-20 2022-03-18 四川大学 Facing type display device and system compatible with magnetic resonance imaging

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050216243A1 (en) * 2004-03-02 2005-09-29 Simon Graham Computer-simulated virtual reality environments for evaluation of neurobehavioral performance
CN201277682Y (en) * 2008-07-29 2009-07-22 妥思空调设备(苏州)有限公司 Low temperature wind feeding anti-condensation cyclone outlet
US20110230755A1 (en) * 2010-03-04 2011-09-22 Macfarlane Duncan Single camera motion measurement and monitoring for magnetic resonance applications
CN104490297A (en) * 2014-11-24 2015-04-08 吴江市格瑞福金属制品有限公司 Portable field barbecue utensil with adjustable flow vent pipe
CN105093532A (en) * 2015-08-03 2015-11-25 京东方科技集团股份有限公司 Virtual reality glasses and display method
CN205992090U (en) * 2016-08-24 2017-03-01 陈尧 A kind of VR glasses using cooperatively with mobile phone
CN108874157A (en) * 2018-09-07 2018-11-23 广州医科大学附属肿瘤医院 A kind of VR equipment and its virtual reality exchange method suitable for MRI
CN209055909U (en) * 2018-09-07 2019-07-02 广州医科大学附属肿瘤医院 A kind of intelligent VR equipment suitable for MRI

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050216243A1 (en) * 2004-03-02 2005-09-29 Simon Graham Computer-simulated virtual reality environments for evaluation of neurobehavioral performance
CN201277682Y (en) * 2008-07-29 2009-07-22 妥思空调设备(苏州)有限公司 Low temperature wind feeding anti-condensation cyclone outlet
US20110230755A1 (en) * 2010-03-04 2011-09-22 Macfarlane Duncan Single camera motion measurement and monitoring for magnetic resonance applications
CN104490297A (en) * 2014-11-24 2015-04-08 吴江市格瑞福金属制品有限公司 Portable field barbecue utensil with adjustable flow vent pipe
CN105093532A (en) * 2015-08-03 2015-11-25 京东方科技集团股份有限公司 Virtual reality glasses and display method
CN205992090U (en) * 2016-08-24 2017-03-01 陈尧 A kind of VR glasses using cooperatively with mobile phone
CN108874157A (en) * 2018-09-07 2018-11-23 广州医科大学附属肿瘤医院 A kind of VR equipment and its virtual reality exchange method suitable for MRI
CN209055909U (en) * 2018-09-07 2019-07-02 广州医科大学附属肿瘤医院 A kind of intelligent VR equipment suitable for MRI

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
LISA M.DI DIODATO等: "A haptic force feedback device for virtual reality-fMRI experiments", 《IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING》 *
RICHARD MRAZ等: "A Platform for Combining Virtual Reality Experiments", 《CYBERPSYCHOLOGY&BEHAVIOR》 *
ROBIN BEKRATER-BODMANN等: "The importance of synchrony and temporal order of visual and tactile input for illusory Limb ownership experiences-An fMRI study applying virtual reality", 《PLOS ONE》 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107822635A (en) * 2017-11-27 2018-03-23 佛山市恒爱网络科技有限公司 Magnetic resonance imaging stimulates machine
CN108874157A (en) * 2018-09-07 2018-11-23 广州医科大学附属肿瘤医院 A kind of VR equipment and its virtual reality exchange method suitable for MRI
CN110192861A (en) * 2019-06-14 2019-09-03 广州医科大学附属肿瘤医院 A kind of intelligence auxiliary brain function real-time detecting system
CN113407024A (en) * 2021-05-25 2021-09-17 四川大学 Evidence display and switching method and device for court trial virtual reality environment
CN114203054A (en) * 2022-01-20 2022-03-18 四川大学 Facing type display device and system compatible with magnetic resonance imaging

Also Published As

Publication number Publication date
CN106901739B (en) 2020-09-15

Similar Documents

Publication Publication Date Title
CN106901739A (en) A kind of virtual reality stimulating apparatus for functional mri
Shin et al. Open access dataset for EEG+ NIRS single-trial classification
CN109992113B (en) MI-BCI system based on multi-scene induction and control method thereof
Thaler et al. Neural correlates of natural human echolocation in early and late blind echolocation experts
Palmisano et al. Stimulus eccentricity and spatial frequency interact to determine circular vection
CN104603673A (en) Head mounted system and method to compute and render stream of digital images using head mounted system
Malaia et al. Event segmentation in a visual language: Neural bases of processing American Sign Language predicates
US4955389A (en) Apparatus for stimulation with optical stimuli
Sakamoto et al. The effects of linearly moving sound images on self-motion perception
CN106551674A (en) Eye-movement measurement device based on simulation spatial disorientation scene
Hara et al. A novel manipulation method of human body ownership using an fMRI-compatible master–slave system
Jouybari et al. Cogno-vest: a torso-worn, force display to experimentally induce specific hallucinations and related bodily sensations
Arpaia et al. A wearable AR-based BCI for robot control in ADHD treatment: Preliminary evaluation of adherence to therapy
CN106618610B (en) Wear terminal system facing to shy children social skill training
CN106020472A (en) Brain computer interface system on basis of motor imageries of different uplifting amplitudes of lower limbs
Yamazaki et al. Implementation of tension-based compact necklace-type haptic device achieving widespread transmission of low-frequency vibrations
Altmann et al. Visual distance cues modulate neuromagnetic auditory N1m responses
Seya et al. Effect of depth order on linear vection with optical flows
Twardon et al. Gaze-contingent audio-visual substitution for the blind and visually impaired
Han et al. Stereoscopic motion perception research based on steady-state visual motion evoked potential
Foerster et al. Impact of iris size and eyelids coupling on the estimation of the gaze direction of a robotic talking head by human viewers
CN113576497A (en) Visual steady-state evoked potential detection system oriented to binocular competition
Virji-Babul et al. Neural mechanisms underlying action observation in adults with down syndrome
Hirsch An fNIRS Approach to Two-person Neuroscience
Sung et al. Cross-modal connectivity of the secondary auditory cortex with higher visual area in the congenitally deaf—A case study

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant