CN106860698A - The preparation method of Chinese herb medicine eye paste - Google Patents
The preparation method of Chinese herb medicine eye paste Download PDFInfo
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- CN106860698A CN106860698A CN201710093844.9A CN201710093844A CN106860698A CN 106860698 A CN106860698 A CN 106860698A CN 201710093844 A CN201710093844 A CN 201710093844A CN 106860698 A CN106860698 A CN 106860698A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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Abstract
The invention discloses a kind of preparation method for treating the Chinese herb medicine eye paste of illness in eye, it is made of the raw material of following component and its parts by weight：Chrysanthemum 10~40, safflower 10~40, illiteracy is close to spend 10~40, Radix Angelicae Sinensis 10~40, cassia seed 10~40, the fruit of Chinese wolfberry 10~40, Ligusticum wallichii 10~50, golden cypress 10~50, borneol 20~60, glycerine 10~40, ethanol water 360~1500, its preparation method is comprised the following steps：A, by chrysanthemum, safflower, cover close flower, Radix Angelicae Sinensis, cassia seed, the fruit of Chinese wolfberry, Ligusticum wallichii, golden cypress, be placed in refluxing extraction 2~5 times in ethanol water, each refluxing extraction 1~5 hour；B, each extract solution is merged, depressurized, be condensed into concentrate, poured into eye refreshing drop is uniformly mixing to obtain in concentrate together with glycerine after borneol is dissolved.C, again the oval spunlace non-woven cloths of 6cm*12cm are soaked in be taken out after 10~30 minutes in the eye refreshing drop and obtain final product the Chinese herb medicine eye paste.
Description
Technical field
It is exactly specifically to be constructed for treating myopia with Chinese medicine the present invention relates to a kind of preparation method of medical supplies
The method of the eye sticker of disease.
Background technology
In recent years, with the popularization of mobile phone, either in market, subway, bus stop, people are the hands of family of bowing
Machine control, play mobile phone oneself through becoming a kind of our habits and customs, hardly realize that the eyesight of this custom let us is more and more lower.
White collar, civil servant, working clan one day face computer at least eight hours, coming off duty will also face mobile phone, TV, and long this can cause
Eyes swollen, the fuzzy, visual impairment of acid, the dry, eye that goes out to lose face is puckery, kopiopia.Adolescent student, for the dependence of electronic product, mistake
Degree eye, it is improper with eye, add visual rehabilitation realize deficienter, learning pressure it is excessive, cause visual problems in juvenile science
Stranger group is in universal phenomenon.Conventional method is rest, eye exercises, eye dropping of eye drops liquid at present, though there is certain alleviation to regard
Fatigue, but because eye dropping of eye drops liquid is contained within preservative, long-term use occurs side effect.Many Chinese medicines are had in recent years
Eye paste application patent of invention, such as Application No. CN201610071717,4, it is entitled " Chinese medicine eye paste " patent, it
The extraction of active ingredient is carried out using water, it has the disadvantage to extract active ingredient soluble in water in medicinal material, but can not extract
The active ingredient of organic solvent is soluble in medicinal material, the waste of medicinal material and the reduction of curative effect is caused.
The content of the invention
It is an object of the invention to provide a kind of preparation method of Chinese herb medicine eye paste.The eye sticker good effect, low cost, consumption medicinal material
Less, it is easy to use.
Chinese herb medicine eye paste of the present invention is made of the raw material of following component and its parts by weight：Chrysanthemum 10~40, safflower 10
~40, cover it is close spend 10~40, Radix Angelicae Sinensis 10~40, cassia seed 10~40, the fruit of Chinese wolfberry 10~40, Ligusticum wallichii 10~50, golden cypress 10~50,
Borneol 20~60, glycerine 10~40, ethanol water 360~1500, its preparation method is comprised the following steps：
, A, by chrysanthemum, safflower, cover close flower, Radix Angelicae Sinensis, cassia seed, the fruit of Chinese wolfberry, Ligusticum wallichii, golden cypress, be placed in ethanol water
In, refluxing extraction 2~5 times, each refluxing extraction 1~5 hour；
B, each extract solution is merged, depressurized, be condensed into concentrate, after borneol is dissolved and glycerine pours into concentrate together
Inside it is uniformly mixing to obtain eye refreshing drop.
C, the oval spunlace non-woven cloths of 6cm*12cm are soaked in the eye refreshing drop are taken out i.e. after 10~30 minutes again
Obtain Chinese herb medicine eye paste.
The parts by weight of each component are optimized for：Chrysanthemum 20~30, safflower 20~30, cover it is close spend 20~30, Radix Angelicae Sinensis 20~
30, cassia seed 20~30, the fruit of Chinese wolfberry 20~30, Ligusticum wallichii 20~40, golden cypress 20~40, borneol 30~50, glycerine 20~30, ethanol
The aqueous solution 800~1100.
Described ethanol water concentration optimization is 55%~90%.
Described refluxing extraction number of times is optimized for 5 times.
Described each extraction time is optimized for 2~3 hours.
It is 6cm*10cm that described oval spunlace non-woven cloth is dimensionally-optimised.
Oval spunlace non-woven cloth soak time in eye refreshing drop is optimized for 20 minutes.
Above-mentioned technical proposal is employed, the traditional traditional Chinese medicine technology of China and modern science and technology are combined, make controlling for illness in eye
Treatment looks for another way, due to using ethanol extract, can fully extract the active ingredient in Chinese medicine, thus it consume medicinal material it is few, drop
Low cost.The active ingredient in Chinese medicine is fully extracted simultaneously so that the active constituent content of eye sticker Chinese medicine increases, so
Good effect.Additionally, due to product be in the form of eye sticker, it is very convenient to use.
The curative effect of eye paste of the present invention, through Beijing Chaoyang Lu dimension eyesight adolescent myopia recovery centre with only do a health care
Behaviour person has carried out contrast test, as a result as follows：
Subjects are primary and secondary students, the age at 7 years old~16 years old, observation group be using the people of eye paste person 60 of the invention,
120 eyes, 2 times a day, 15 minutes every time~20 minutes.
Control group is the people of person 50 that only does eye exercises, totally 100 eyes, 15 days as one therapeutic course, and two groups of clinical test results are such as
Under：
Lifting：Binocular vision recovers more than two lattice.
Effectively：Binocular vision recovers more than a lattice.
It is invalid：Eyesight is without change.
Above-mentioned result of the test shows that eye paste of the present invention has significant curative effect four, specific embodiment to recovering eyesight
With reference to embodiment, the present invention is further illustrated
Embodiment 1：
(1) chrysanthemum 1000g, safflower 4000g are taken, close colored 1000g, Radix Angelicae Sinensis 4000g, cassia seed 1000g, the fruit of Chinese wolfberry is covered
4000g, Ligusticum wallichii 1000g, golden cypress 5000g is placed in stainless steel extraction vessel, adds the ethanol water 80 that concentration is 90% public
Jin, refluxing extraction 5 times, each refluxing extraction 1 hour.
(2) No. 5 extract solutions merged, depressurize, be condensed into concentrate, after 6000g borneols are dissolved and 1000g glycerine together
Pour into and eye refreshing drop is uniformly mixing to obtain in concentrate.
(3) again the oval spunlace non-woven cloths of 6cm*10cm are soaked in be taken out after 30 minutes in the eye refreshing drop and obtain final product institute
State eye paste.
Claims (7)
1. the preparation method of Chinese herb medicine eye paste, it is characterized in that：It is made of the raw material of following component and its parts by weight：Chrysanthemum 10
~40, safflower 10~40, cover it is close spend 10~40, Radix Angelicae Sinensis 10~40, cassia seed 10~40, the fruit of Chinese wolfberry 10~40, Ligusticum wallichii 10~
50, golden cypress 10~50, borneol 20~60, glycerine 10~40, ethanol water 360~1500, its preparation method includes following step
Suddenly：A, by chrysanthemum, safflower, cover close flower, Radix Angelicae Sinensis, cassia seed, the fruit of Chinese wolfberry, Ligusticum wallichii, golden cypress, the red sage root, be placed in ethanol water,
Refluxing extraction 2~5 times, each refluxing extraction 1~5 hour；B, each extract solution is merged, depressurized, concentrate be condensed into, by ice
Pour into eye refreshing drop is uniformly mixing to obtain in concentrate together with glycerine after piece dissolves.C, again by 6cm*12cm oval spun lacing without
Spin cloth and be soaked in the eye refreshing drop to be taken out after 10~30 minutes and obtain final product Chinese herb medicine eye paste.
2. the preparation method of Chinese herb medicine eye paste as claimed in claim 1, it is characterized in that：The parts by weight of described each component are：
Chrysanthemum 20~30, safflower 20~30, illiteracy is close to spend 20~30, Radix Angelicae Sinensis 20~30, cassia seed 20~30, the fruit of Chinese wolfberry 20~30, river
Rhizome of chuanxiong 20~40, golden cypress 20~40, borneol 30~50, glycerine 20~30, ethanol water 800~1100.
3. the preparation method of Chinese herb medicine eye paste as claimed in claim 1, it is characterized in that：Described ethanol water concentration is 55%
~90%.
4. the preparation method of Chinese herb medicine eye paste as claimed in claim 1, it is characterized in that：Described refluxing extraction number of times is 5 times.
5. the preparation method of Chinese herb medicine eye paste as claimed in claim 1, it is characterized in that：Described each extraction time is 2~3 small
When.
6. the preparation method of Chinese herb medicine eye paste as claimed in claim 1, it is characterized in that：Described oval spunlace non-woven cloth is
6cm*10cm。
7. the preparation method of Chinese herb medicine eye paste as claimed in claim 1, it is characterized in that：Described oval spunlace non-woven cloth is in shield
Soak time is 20 minutes in ocular fluid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710093844.9A CN106860698A (en) | 2017-02-21 | 2017-02-21 | The preparation method of Chinese herb medicine eye paste |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710093844.9A CN106860698A (en) | 2017-02-21 | 2017-02-21 | The preparation method of Chinese herb medicine eye paste |
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| CN201710093844.9A Pending CN106860698A (en) | 2017-02-21 | 2017-02-21 | The preparation method of Chinese herb medicine eye paste |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108175806A (en) * | 2018-01-23 | 2018-06-19 | 贵州康琦药械有限公司 | A kind of Chinese medicine eye paste and preparation method thereof |
| CN108619239A (en) * | 2018-05-25 | 2018-10-09 | 广州奢元素生物科技有限公司 | A kind of pure plant eyeshield health care packet and the preparation method and application thereof |
| CN109431974A (en) * | 2018-12-11 | 2019-03-08 | 浙江越医健康产业有限公司 | A kind of eye point massage cream and preparation method thereof |
| CN109700889A (en) * | 2019-03-05 | 2019-05-03 | 朱月新 | A kind of Chinese medicine composition and preparation method thereof of health care eyes |
| JP2020045338A (en) * | 2018-09-12 | 2020-03-26 | 大正製薬株式会社 | External composition |
| CN112546156A (en) * | 2020-12-30 | 2021-03-26 | 北京国科惠眼科技有限公司 | Traditional Chinese medicine composition for treating eyesight, preparation method, preparation and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168984A (en) * | 2015-11-03 | 2015-12-23 | 徐冰娜 | Chinese herbal compound eye plaster for treating ophthalmic diseases |
| CN106266302A (en) * | 2016-07-21 | 2017-01-04 | 北京维视力中医药技术有限公司 | The manufacture method of Chinese herb medicine eye paste |
-
2017
- 2017-02-21 CN CN201710093844.9A patent/CN106860698A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168984A (en) * | 2015-11-03 | 2015-12-23 | 徐冰娜 | Chinese herbal compound eye plaster for treating ophthalmic diseases |
| CN106266302A (en) * | 2016-07-21 | 2017-01-04 | 北京维视力中医药技术有限公司 | The manufacture method of Chinese herb medicine eye paste |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108175806A (en) * | 2018-01-23 | 2018-06-19 | 贵州康琦药械有限公司 | A kind of Chinese medicine eye paste and preparation method thereof |
| CN108619239A (en) * | 2018-05-25 | 2018-10-09 | 广州奢元素生物科技有限公司 | A kind of pure plant eyeshield health care packet and the preparation method and application thereof |
| JP2020045338A (en) * | 2018-09-12 | 2020-03-26 | 大正製薬株式会社 | External composition |
| CN109431974A (en) * | 2018-12-11 | 2019-03-08 | 浙江越医健康产业有限公司 | A kind of eye point massage cream and preparation method thereof |
| CN109700889A (en) * | 2019-03-05 | 2019-05-03 | 朱月新 | A kind of Chinese medicine composition and preparation method thereof of health care eyes |
| CN112546156A (en) * | 2020-12-30 | 2021-03-26 | 北京国科惠眼科技有限公司 | Traditional Chinese medicine composition for treating eyesight, preparation method, preparation and application thereof |
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Application publication date: 20170620 |