CN106859685A - A kind of image rebuilding method, device and equipment - Google Patents
A kind of image rebuilding method, device and equipment Download PDFInfo
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Abstract
The application provides a kind of image rebuilding method, device and equipment, and methods described includes：Determine the crystal efficiency factor and geometrical factor of the single crystal of crystal centering, the crystal is to being the crystal pair in crystal rings in PET device；The crystal efficiency factor and geometrical factor according to the single crystal of crystal centering determine the sensitivity of the crystal pair；Obtain the data to scanning patient by the crystal；Data are corrected using the sensitivity of the crystal pair；Image reconstruction is carried out according to the data after correction.In the application, the crystal efficiency factor and geometrical factor according to single crystal determine the sensitivity of crystal pair, and the data for scanning effectively are corrected using the sensitivity, improve the accuracy of image reconstruction.In addition, the application is corrected by the background radiation to crystal, without buying radioactive source, making radiation source device, the geometrical factor for having calculated crystal pair is concisely and efficiently, not only reduces cost, it is thus also avoided that the radiation risk of operating personnel.
Description
Technical field
The application is related to technical field of medical equipment, more particularly to a kind of image rebuilding method, device and equipment.
Background technology
Positron Emission Computed Tomography (PET, positron emission tomography) equipment is current
Generally acknowledge one of state-of-the-art large-scale medical scientific research and clinical diagnostic device, in diagnosing tumour, the disease such as cardiovascular disease aspect has
Remarkable performance.During PET device collection patient data, because the polygon geometry of PET device can cause crystalline substance
The sensitivity (efficiency) of body pair is inconsistent so that it is poor that the data number of collection exists with the data number being actually sent out in patient body
Not, and then reconstruct the image for coming and cannot correctly reflect the distribution situation of radioactive element activity in patient body.
In order to solve the problem, propose carries out geometric correction in the prior art to the data of PET device collection.To ensure
Crystal to sensitivity uniformity, specially：One (external) is placed in PET device central region uniformly radiate source device,
The photon pair that collection radioactive source (such as rotating rod source, plane source, annular source and mobile line source etc.) sends, followed by collection
Data, design corresponding correcting algorithm, calculate the geometric correction factor of each pair crystal pair.
In the prior art, although can be by correcting the geometrical factor of crystal pair, it is ensured that crystal comes to the uniformity of sensitivity
The accuracy of image reconstruction is improved, but, in existing this mode, on the one hand, need to place transmitting source device, and put outward
Source device design complexity is penetrated, radioactive source is not easy to store, shields, and expensive；On the other hand, trimming process needs work people
Member manipulates radiation source device, and the ray that radioactive source sends can cause radiation risk to the body of staff.
The content of the invention
In view of this, the application provides a kind of image rebuilding method, device and equipment, with several in PET device by reducing
What factor correction cost, and the radiation risk that is brought of correction geometrical factor improves the accuracy of image reconstruction.
Specifically, the application is achieved by the following technical solution：
First aspect, there is provided a kind of image rebuilding method, methods described includes：
Determine the crystal efficiency factor and geometrical factor of the single crystal of crystal centering, wherein, the crystal is to being PET device
Crystal pair in middle crystal rings；
The crystal efficiency factor and geometrical factor according to the single crystal of crystal centering determine the sensitive of the crystal pair
Degree；
Obtain the data to scanning patient by the crystal；
The data are corrected using the sensitivity of the crystal pair；
Image reconstruction is carried out according to the data after correction.
Second aspect provides a kind of equipment for reconstructing image, and described device includes：
First determining unit, the crystal efficiency factor and geometrical factor for determining the single crystal of crystal centering, wherein, institute
Crystal is stated to being the crystal pair in crystal rings in PET device；
Described in second determining unit, the crystal efficiency factor according to the single crystal of crystal centering and geometrical factor determine
The sensitivity of crystal pair；
Acquiring unit, for obtaining the data by the crystal to scanning patient；
The data are corrected by correction unit for the sensitivity using the crystal pair；
Reconstruction unit, for carrying out image reconstruction according to the data after correction.
The third aspect provides a kind of Medical Devices, including：Processor；And for storing the processor-executable instruction
Memory；Wherein,
The processor is configured as：
Determine the crystal efficiency factor and geometrical factor of the single crystal of crystal centering, wherein, the crystal is to being PET device
Crystal pair in middle crystal rings；
The crystal efficiency factor and geometrical factor according to the single crystal of crystal centering determine the sensitive of the crystal pair
Degree；
Obtain the data to scanning patient by the crystal；
The data are corrected using the sensitivity of the crystal pair；
Image reconstruction is carried out according to the data after correction.
In the embodiment of the present application, the crystal efficiency factor and geometrical factor of the single crystal of crystal centering are first determined, according to institute
The crystal efficiency factor and geometrical factor for stating the single crystal of crystal centering determine the sensitivity of crystal pair, then, using crystal pair
Sensitivity the data for getting patient are corrected, and carry out image reconstruction according to the data after correction.That is, this
In application embodiment, the crystal efficiency factor and geometrical factor according to single crystal determine the sensitivity of crystal pair, and utilization should
Sensitivity is effectively corrected to the data for scanning, and improves the accuracy of image reconstruction.In addition, by the background spoke to crystal
Penetrate and be corrected, without buying radioactive source, making radiation source device, be concisely and efficiently the geometrical factor for having calculated crystal pair,
Not only reduce cost, it is thus also avoided that the radiation risk of operating personnel.
It should be appreciated that the general description of the above and detailed description hereinafter are only exemplary and explanatory, not
The application can be limited.
Brief description of the drawings
Fig. 1 is a kind of flow chart of image rebuilding method that the embodiment of the present application is provided；
Fig. 2 is a kind of flow chart of the sensitivity of determination crystal pair that the embodiment of the present application is provided；
Fig. 3 is the schematic diagram that a kind of crystal background that the embodiment of the present application is provided meets event；
Fig. 4 is a kind of schematic diagram of calculating crystal efficiency factor that the embodiment of the present application is provided；
Fig. 5 is a kind of hardware knot of the crystal to image reconstruction device where equipment for reconstructing image of the embodiment of the present application offer
Composition；
Fig. 6 is a kind of structural representation of equipment for reconstructing image that the embodiment of the present application is provided；
Fig. 7 is a kind of another structural representation of equipment for reconstructing image that the embodiment of the present application is provided；
Fig. 8 is a kind of another structural representation of equipment for reconstructing image that the embodiment of the present application is provided；
Fig. 9 is a kind of another structural representation of equipment for reconstructing image that the embodiment of the present application is provided；
Figure 10 is a kind of another structural representation of equipment for reconstructing image that the embodiment of the present application is provided.
Specific embodiment
Here exemplary embodiment will be illustrated in detail, its example is illustrated in the accompanying drawings.Following description is related to
During accompanying drawing, unless otherwise indicated, the same numbers in different accompanying drawings represent same or analogous key element.Following exemplary embodiment
Described in implementation method do not represent all implementation methods consistent with the application.Conversely, they be only with it is such as appended
The example of the consistent apparatus and method of some aspects described in detail in claims, the application.
It is the purpose only merely for description specific embodiment in term used in this application, and is not intended to be limiting the application.
" one kind ", " described " and " being somebody's turn to do " of singulative used in the application and appended claims is also intended to include majority
Form, unless context clearly shows that other implications.It is also understood that term "and/or" used herein refers to and wraps
May be combined containing one or more associated any or all of project listed.
It will be appreciated that though various information, but this may be described using term first, second, third, etc. in the application
A little information should not necessarily be limited by these terms.These terms are only used for being distinguished from each other open same type of information.For example, not departing from
In the case of the application scope, the first information can also be referred to as the second information, and similarly, the second information can also be referred to as
One information.Depending on linguistic context, word as used in this " if " can be construed to " ... when " or " when ...
When " or " in response to determining ".
Fig. 1 is referred to, is a kind of flow chart of image rebuilding method that the embodiment of the present application is provided；Methods described includes：
Step 101：Determine the crystal efficiency factor and geometrical factor of the single crystal of crystal centering, wherein, the crystal pair
It is the crystal pair in crystal rings in PET device；
In the step, the process of a kind of crystal efficiency factor for determining the single crystal of crystal centering and geometrical factor is：
First collection crystal meets event to upper multiple backgrounds；The multiple background is met into event and is divided into first kind sheet
Bottom meets event and Equations of The Second Kind background meets event；Then, it is determined that first kind background meets the first crystal efficiency factor of event,
And Equations of The Second Kind background meets the second crystal efficiency factor of event；And using the first crystal efficiency factor to described first
Class background meets event and is corrected, and first kind background meets event after being corrected, and utilizes second crystal efficiency
Equations of The Second Kind background meets event and is corrected described in factor pair, and Equations of The Second Kind background meets event after being corrected；Finally, using every
Meet the first kind background after upper correction crystal event and meet sum of events with Equations of The Second Kind background, determine the crystal to upper
Corresponding first geometrical factor of single crystal and the second geometrical factor.
The detailed process of the crystal efficiency factor and geometrical factor Fig. 2 as described below of its determination single crystal of crystal centering is extremely
The description of Fig. 4, will not be repeated here.
Step 102：The crystal efficiency factor and geometrical factor according to the single crystal of crystal centering determine the crystal
To sensitivity；
In the step, the first crystal efficiency factor, the second crystal efficiency factor, first that will be obtained in step 101
Geometrical factor and the first geometrical factor are multiplied respectively, obtain the sensitivity of crystal pair.It is referred to as the sensitivity mould of crystal pair
Type.
That is, crystal can be set up to the sensitivity model of i-j by formula (1)：
ηij=εiεjgigj (1)
Wherein, ηijSensitivity of the crystal to i-j is represented, i-j represents the single crystal of crystal centering, ε respectivelyi(or εj) represent
Single crystal i (or j) the crystal efficiency factor, gi(or gj) geometrical factor of single crystal i (or j) is represented, reflection is single
The inclination angle of individual crystal receives it influence of single photon.
Step 103：Obtain the data to scanning patient by the crystal；
In the step, when patient is scanned using PET device, PET device obtains the data to scanning patient by crystal.
Step 104：The data are corrected using the sensitivity of the crystal pair；
In the step, the process being corrected to the data using the sensitivity of crystal pair is for those skilled in the art
For, it has been to know technology, will not be repeated here.
Step 105：Image reconstruction is carried out according to the data after correction.
In the step, image reconstruction process is carried out to those skilled in the art according to the data after correction, be
Know technology, will not be repeated here.
In the embodiment of the present application, the crystal efficiency factor and geometrical factor of the single crystal of crystal centering are first determined, according to institute
The crystal efficiency factor and geometrical factor for stating the single crystal of crystal centering determine the sensitivity of crystal pair, then, using crystal pair
Sensitivity the data for getting patient are corrected, and carry out image reconstruction according to the data after correction.That is, this
In application embodiment, the crystal efficiency factor and geometrical factor according to single crystal determine the sensitivity of crystal pair, and utilization should
Sensitivity is effectively corrected to the data for scanning, and improves the accuracy of image reconstruction.In addition, the present embodiment is by crystal
Background radiation be corrected, without buy radioactive source, make radiation source device, be concisely and efficiently and calculated the several of crystal pair
What factor, not only reduces cost, it is thus also avoided that the radiation risk of operating personnel.
Fig. 2 is referred to, is a kind of flow chart of the crystal that provides of the embodiment of the present application to the bearing calibration of geometrical factor；Institute
The method of stating includes：
Step 201：Collection crystal meets event to upper multiple backgrounds；
In the step, PET device collects crystal and meets event to upper multiple backgrounds, and each background meets event and includes：
First kind background meets event and Equations of The Second Kind background meets event.
In the embodiment, PET device includes crystal rings, wherein, each crystal in crystal rings can be with background
The crystal of radiation, such as (such as LYSO crystal) containing lutetium (Lu) crystal, Lu elements therein can occur in the state of nature β-
Decay, the γ photons of three kinds of different-energy ranks of simultaneous send, respectively 307KeV, 202KeV, 88KeV, decay
There is ionisation effect in the β particles for sending, discharge the energy of 590Kev or so in crystal, and the crystal where it is detected,
I.e. β particles can be by crystal " absorption ".Meanwhile, the γ photons that decay sends flee from the crystal, are flown in the visual field a period of time, quilt
Another crystal is detected in annular detector in PET device, as shown in figure 3, one kind that Fig. 3 is provided for the embodiment of the present application
Crystal background meets the schematic diagram of event.As illustrated, 202 when representing the Lu element decays in crystal i, β elements are by crystal i
" absorption ", γ photons are received by crystal j；201 represent the process opposite with 202, m, and n represents two other crystalline substance in crystal rings
Body.
In order to succinct, convenient treatment Lu element decays send three in different-energy rank γ photons, by set
The method of energy threshold removes the γ photons that energy is 202kev and 88kev, only collects the γ photons of 307kev.
In the embodiment, one energy threshold Δ E is set to PET device in advance, one meets time window Δ T, under satisfaction
Event referred to as this eradiation for stating condition meets event.
If the energy of two particles of the crystal to measuring meets energy threshold Δ E, and the two particles are detected by crystal
To time interval meeting in event window Δ T, then the two particles are referred to as a background and meet event.Whenever crystal is to i-j
When having a background to meet event generation on (wherein, i and j represent the single crystal of crystal pair respectively), crystal is to i-j in circuit
In corresponding certain position counting can add 1, now, PET device collects above-mentioned background and meets event, and is preserved.
Step 202：By the multiple background meet event be divided into first kind background meet event and Equations of The Second Kind background symbol
Conjunction event；
In the step, a kind of dividing mode is：The multiple background is met into event according to energy threshold and is divided into first
Class background meets event and Equations of The Second Kind background meets event, wherein, energy threshold is set in advance, is divided according to energy threshold
Background meets event to those skilled in the art, has been to know technology, will not be repeated here.
Step 203：Determine that first kind background meets the first crystal efficiency factor of event, and Equations of The Second Kind background meets thing
The second crystal efficiency factor of part；
It is γ particles due to collect background meeting in event one in the step, one is β particles, and β particles are with probability
1 is absorbed by single crystal i (or j), specific as shown in Fig. 2 and γ particles fly out from the single crystal i (or j) and get to opposite
Received by single crystal j (or i) on single crystal j (or i), therefore, what background met event reflection is single crystal j (or i)
Receive the efficiency (effect of β particles is by means of it is determined that going out its corresponding γ photon) of γ particles.But, in PET device
In actual use, what is sent in patient body is 2 γ photons, and it meets event by what two crystal were absorbed respectively, i.e.
One meets event and reflects that two crystal receive the efficiency of photon.
That is, any pair of crystal is to when reception meets event, its efficiency is both subject to crystal intrinsic efficiency
Influence, also influenceed by equipment circular geometry, calculate crystal pair the geometric correction factor before, first to remove crystalline substance
The influence of body intrinsic efficiency.
Therefore, a kind of calculation (the present embodiment is as a example by calculating first crystal efficiency factor) of the crystal efficiency factor
For：
Meet knowable to the feature of event because Fig. 3 illustrates background, crystal meets event (i.e. to the background that i-j is collected
Data, that is to say, that data meet event and constitute by multiple backgrounds) there are two types, i.e., 201 and 202, herein, 201
Referred to as first kind background meets event, and 202 are referred to as Equations of The Second Kind background meets event.Wherein, 201 represent that crystal i receives γ photons
Background meet event, the background that 202 expression crystal j receive γ photons meets event.Assuming that crystal is to the sheet that is collected on i-j
Bottom meets aggregate event number for n, then 201 backgrounds comprising certain amount meet event and 202 backgrounds of certain amount meet in n
Event.
Because β particles are different from γ particle energys, can be judged by the energy threshold of the particle detected to crystal i
The particle that crystal i is detected is β or γ, i.e., it is 201 or 202 that the background meets event.If, if nijCount
202 backgrounds meet the total number of event, then 201 backgrounds meet total number of events mesh for nij=n-nji。
The intrinsic efficiency of crystal i is calculated, event is met to the background collected on i-j to crystal, the present embodiment is this with 201
The background of type meets as a example by event.201 backgrounds according to collecting meet event nij, crystal is calculated using fan-beam algorithm
To the efficiency correction factor (i.e. first crystal efficiency factor) of upper single crystal i, the formula of its fan-beam algorithm is：
Wherein, N represents crystal number total on annular detector, jminRepresent the starting crystals numbering of fan-beam, jmaxRepresent
The termination crystal numbering of fan-beam, nijRepresent that first kind background meets the first count totals of event, εiRepresent first crystal efficiency
The factor.
Similarly, the second background of statistics meets the second count totals n of eventji, according to the second count totals nji, profit
The efficiency correction factor (i.e. the second crystal efficiency factor) of the crystal to upper single crystal j is calculated with fan-beam algorithm, its fan
The formula of beam algorithm is：
Wherein, N represents crystal number total on annular detector, jminRepresent the starting crystals numbering of fan-beam, jmaxRepresent
The termination crystal numbering of fan-beam, njiRepresent that the second background meets the second count totals of event, εjRepresent the second crystal efficiency because
Son.
Wherein, jminAnd jmaxIt is specific as shown in figure 4, one kind calculating crystal efficiency that Fig. 4 is the embodiment of the present application to be provided because
The schematic diagram of son.
In addition, the efficiency factor (i.e. the second crystal efficiency factor) of crystal j is calculated needing according to crystal to 202 on i-j
Such background meets event, the data type of the calculating of other crystal efficiency factors or with crystal i use
It is identical or identical with crystal j that background meets event type, and its calculating process is similar to, and will not be repeated here.
Step 204：Meet event to the first kind background using the first crystal efficiency factor to be corrected, obtain
First kind background meets event after correction, and meets event using Equations of The Second Kind background described in the second crystal efficiency factor pair
It is corrected, Equations of The Second Kind background meets event after being corrected；
In the step, event is met to corresponding background respectively using the crystal efficiency factor and is corrected,
Due to obtaining the efficiency correction factor ε of each crystal in crystal ringsiAfter (i=1~N), in addition it is also necessary to utilization ratio school
Positive divisor εiMeeting event to the background on i-j to crystal carries out crystal efficiency correction, and the purpose of its correction is to remove crystal to consolidate
The influence that effective percentage brings, then computational geometry correction factor again.
It is contemplated that background meets event only being influenceed by a crystal, crystal is met being collected into background on i-j
The tale n of event carries out crystal efficiency timing, it is necessary to the 201 and 202 event ε for being included to it respectivelyiAnd εjIndependent school
Just, it is n'ji=nji*εj, wherein n'jiRepresent 202 events after crystal efficiency correction, n'ji=nji*εj, n 'ij=nij*εi,
Now crystal on i-j to meeting total number of events mesh for n'=n 'ij+n'ji。
Step 205：Meet the first kind background after upper correction event using each pair crystal and meet thing with Equations of The Second Kind background
The sum of part, determines the crystal to corresponding first geometrical factor of upper single crystal and the second geometrical factor；
In the step, the method from the existing geometrical factor for directly calculating each pair crystal pair is different, and the present embodiment is considered
Background meets the feature of event, it is proposed that individually calculate the geometrical factor of each crystal, and then the recombinant geometrical factor, obtains
The geometrical factor of crystal pair.
As shown in Figure 3, it is assumed that M is had on the direction along crystal to i-j to crystal to (such as crystal is and crystalline substance to m-n
Body have to i-j the crystal of equidirectional to), respectively：Xtali1Xtalj1, Xtali2Xtalj2... XtaliMXtaljM, each pair crystalline substance
The tale that background on body after crystal efficiency factor correction meets event is n '1, n'2... n'M, then single crystal Xtalik(or
Person Xtaljk) the geometric correction factor of (k=1~N) can be obtained by normalization algorithm, wherein, a kind of public affairs of normalization algorithm
Formula is：
Wherein, due to crystal Xtaljk(or Xtalik) receive data when by geometry influenceed and Xtalik(or
Person Xtaljk) identical, so, gjkThe geometric correction factor can also be obtained by normalization algorithm, a kind of its normalization algorithm
Computing formula such as formula (4) shown in, its calculating process and gikThe geometric correction factor calculating process be similar to, specifically refer to
State, will not be repeated here.
Further, on the basis of above-described embodiment, can be with：The first geometrical factor and the second geometrical factor are combined, is obtained
To the geometrical factor of crystal pair, it is also possible to combine first crystal efficiency factor and the second crystal efficiency factor, obtain the crystal pair
The crystal efficiency factor, below as a example by combining the first geometrical factor and the second geometrical factor, its interwoven crystal efficiency factor with
It is similar to.
In the step, a kind of combination is that first geometrical factor is multiplied by into second geometrical factor, obtains crystalline substance
The geometrical factor of body pair.
That is, crystal is to XtalikXtaljkThe geometric correction factor of (k=1~N) is：
gikjk=gik*gjk (5)
Therefore, according to formula (2A), (2B) and (5), sensitivity of the crystal to i-j can be by means of the model of above-mentioned foundation
Formula (1) obtain.
In the embodiment of the present application, the multiple backgrounds that will be collected meet event and are divided into different types of background and meet thing
Part, meets event and calculates the corresponding crystal efficiency factor respectively, then using the crystal efficiency for calculating according to corresponding background
Corresponding background meets event before factor correction, and it is single to meet the background after upper correction event calculating using each pair crystal
The geometrical factor of crystal, then, the crystal efficiency factor and geometrical factor according to the single crystal of crystal centering determine crystal
To sensitivity, the data for getting patient are corrected using the sensitivity of crystal pair, and entered according to the data after correction
Row image reconstruction.That is, in the embodiment of the present application, the crystal efficiency factor and geometrical factor according to single crystal determine brilliant
The sensitivity of body pair, and the data for scanning effectively are corrected using the sensitivity, improve the accuracy of image reconstruction.Separately
Outward, the present embodiment is corrected by the background radiation to crystal, succinct high without buying radioactive source, making radiation source device
The geometrical factor for having calculated crystal pair of effect, not only reduces cost, it is thus also avoided that the radiation risk of operating personnel.
Embodiment with foregoing image rebuilding method is corresponding, present invention also provides the embodiment of equipment for reconstructing image.
The embodiment of the equipment for reconstructing image that the application is provided can be applied on image reconstruction device, and the image reconstruction sets
Standby can be host computer.As shown in figure 5, one of image reconstruction device where the equipment for reconstructing image provided for the embodiment of the present application
Hardware structure diagram is planted, the image reconstruction device can include processor 501 and machinable medium 502, wherein, treatment
Device 501 and machinable medium 502 are generally connected with each other by internal bus 503.In other possible implementations,
The equipment is also possible that external interface 504, can be communicated with other equipment or part.Further, machine
Be stored with the control logic 505 of image reconstruction on readable storage medium storing program for executing 502, the logic that the control logic 505 is functionally divided
Module, can be the structure of the equipment for reconstructing image shown in Fig. 6.
Fig. 6 is refer to, is a kind of structural representation of equipment for reconstructing image that the embodiment of the present application is provided, described device bag
Include：First determining unit 61, the second determining unit 62, acquiring unit 63, correction unit 64 and reconstruction unit 65, wherein,
First determining unit 61, the crystal efficiency factor and geometrical factor for determining the single crystal of crystal centering, wherein,
The crystal is to being the crystal pair in crystal rings in PET device；
Second determining unit 62, the crystal efficiency factor and geometrical factor according to the single crystal of crystal centering determine institute
State the sensitivity of crystal pair；
Acquiring unit 63, for obtaining the data by the crystal to scanning patient；
The data are corrected by correction unit 64 for the sensitivity using the crystal pair；
Reconstruction unit 65, for carrying out image reconstruction according to the data after the correction unit correction.
Optionally, in another embodiment, the embodiment is on the basis of above-described embodiment, first determining unit 61
Including：Collecting unit 71, division unit 72, efficiency factor determining unit 73, event correction unit 74 and geometrical factor determine single
Unit 75, its structural representation as shown in fig. 7, wherein,
Upper multiple backgrounds are met event by collecting unit 71 for gathering crystal；
Division unit 72, is divided into first kind background for the multiple background to be met into event and meets event and Equations of The Second Kind
Background meets event；
Efficiency factor determining unit 73, for determining that first kind background meets the first crystal efficiency factor of event, and
Equations of The Second Kind background meets the second crystal efficiency factor of event；
Event correction unit 74, enters for meeting event to the first kind background using the first crystal efficiency factor
Row correction, first kind background meets event after being corrected, and using Equations of The Second Kind described in the second crystal efficiency factor pair
Background meets event and is corrected, and Equations of The Second Kind background meets event after being corrected；
Geometrical factor determining unit 75, for meeting the first kind background after upper correction event and the using each pair crystal
Two class backgrounds meet sum of events, determine the crystal to corresponding first geometrical factor of upper single crystal and the second geometry because
Son.
Optionally, in another embodiment, on the basis of above-described embodiment, the division unit 72 has the embodiment
Body is used to the multiple background is met into event according to energy threshold and is divided into first kind background and meets event and Equations of The Second Kind background
Meet event.
Optionally, in another embodiment, on the basis of above-described embodiment, the efficiency factor determines single the embodiment
Unit 73 includes：Statistic unit 731 and computing unit 732, its structural representation as shown in figure 8, wherein,
Statistic unit 731, the first count totals and the second background that event is met for counting first kind background meet thing
Second count totals of part；
Computing unit 732, by according to first count totals and the second count totals using fan-beam algorithm respectively based on
Calculate first crystal efficiency factor and the second crystal efficiency factor.
Wherein it is possible to utilize formula according to the first count totalsCalculate first crystal efficiency factor；
And utilize formula according to second count totalsCalculate the second crystal efficiency factor；
Wherein, N represents crystal number total on annular detector, jminRepresent the starting crystals numbering of fan-beam, jmaxRepresent
The termination crystal numbering of fan-beam, nijRepresent that first kind background meets the first count totals of event, njiRepresent that the second background meets
Second count totals n of eventji, εiRepresent first crystal efficiency factor, εjRepresent the second crystal efficiency factor.
Optionally, in another embodiment, the embodiment is on the basis of above-described embodiment, the event correction unit 74
Including：The first correction correction subelement 742 of subelement 741 and second, its structural representation as shown in figure 9, wherein,
First correction subelement 741, thing is met for the first crystal efficiency factor to be multiplied by into the first kind background
Part, the first kind background after being corrected meets event；
Second correction subelement 742, thing is met for the second crystal efficiency factor to be multiplied by into the Equations of The Second Kind background
Part, the Equations of The Second Kind background after being corrected meets event.
Optionally, in another embodiment, on the basis of above-described embodiment, the geometrical factor determines single the embodiment
Unit 75 includes：First determination subelement 751 and the second determination subelement 752, its structural representation are as shown in Figure 10, wherein,
First determination subelement 751, for meeting the upper first kind background event and the according to each pair crystal after correction
Two class backgrounds meet sum of events, and first geometrical factor of the crystal to a upper crystal is calculated using normalization algorithm；
Second determination subelement 752, for meeting the upper first kind background event and the according to each pair crystal after correction
Two class backgrounds meet sum of events, and second geometrical factor of the crystal to upper another crystal is calculated using normalization algorithm.
Optionally, in another embodiment, on the basis of above-described embodiment, the efficiency factor determines single the embodiment
Unit 76 can also include：First assembled unit and/or the second assembled unit (not shown), wherein,
First assembled unit, for combining first geometrical factor and the second geometrical factor, obtains the geometry of crystal pair
The factor；
Second assembled unit, for combining the first crystal efficiency factor and the second crystal efficiency factor, obtains crystal
To the crystal efficiency factor.
The function of unit and the implementation process of effect correspond to step in specifically referring to the above method in said apparatus
Implementation process, will not be repeated here.
In different examples, the machinable medium 502 can be：RAM (Radom Access Memory,
Random access memory), volatile memory, nonvolatile memory, flash memory, memory driver (such as hard disk drive), solid-state
Hard disk, any kind of storage dish (such as CD, dvd), or similar storage medium, or combinations thereof.
In the embodiment of the present application, the crystal efficiency factor and geometrical factor of the single crystal of crystal centering, then, root are first determined
Determine the sensitivity of the crystal pair according to the crystal efficiency factor and geometrical factor of the single crystal of crystal centering, and using brilliant
The sensitivity of body pair is corrected to the data for getting patient, finally carries out image reconstruction using the data after correction, improves
The accuracy of image reconstruction.That is, in the embodiment of the present application, the crystal efficiency factor and geometry according to single crystal because
Son determines the sensitivity of crystal pair, and the data for scanning effectively are corrected using the sensitivity, improves image reconstruction
Accuracy.In addition, the present embodiment is corrected by the background radiation to crystal, without buying radioactive source, making radioactive source dress
Put, be concisely and efficiently the geometrical factor for having calculated crystal pair, not only reduce cost, it is thus also avoided that the radiation danger of operating personnel
Danger.
In addition, the embodiment of the present application also provides a kind of Medical Devices, including：Processor；And for storing the treatment
The memory of device executable instruction；The memory can be machinable medium, wherein,
The processor is configured as：
Determine the crystal efficiency factor and geometrical factor of the single crystal of crystal centering, wherein, the crystal is to being PET device
Crystal pair in middle crystal rings；
The crystal efficiency factor and geometrical factor according to the single crystal of crystal centering determine the sensitive of the crystal pair
Degree；
Obtain the data to scanning patient by the crystal；
The data are corrected using the sensitivity of the crystal pair；
Image reconstruction is carried out according to the data after correction.
Wherein it is determined that the crystal efficiency factor and geometrical factor of the single crystal of crystal centering, including：
Collection crystal meets event to upper multiple backgrounds；
The multiple background is met into event and is divided into that first kind background meets event and Equations of The Second Kind background meets event；
Determine that first kind background meets the first crystal efficiency factor of event, and Equations of The Second Kind background meets the second of event
The crystal efficiency factor；
Meet event to the first kind background using the first crystal efficiency factor to be corrected, after being corrected
One class background meets event, and meets event using Equations of The Second Kind background described in the second crystal efficiency factor pair and carry out school
Just, Equations of The Second Kind background meets event after being corrected；
Meet the first kind background after upper correction event using each pair crystal and meet sum of events with Equations of The Second Kind background, really
The fixed crystal is to corresponding first geometrical factor of upper each crystal and the second geometrical factor.
In the embodiment of the present application, the multiple backgrounds that will be collected meet event and are divided into different types of background and meet thing
Part, meets event and calculates the corresponding crystal efficiency factor respectively, then using the crystal efficiency for calculating according to corresponding background
Corresponding background meets event before factor correction, finally, meets the background after upper correction event using each pair crystal and calculates
The geometrical factor of single crystal, then the geometrical factor of the single crystal of recombinant, obtains the collecting factor of crystal pair.Namely
Say, in the embodiment of the present application, according to the characteristics of equipment crystal, set up corresponding crystal to sensitivity model, radiated without purchase
Source, making radiation source device, are concisely and efficiently the geometrical factor for having calculated crystal pair, not only reduce cost, it is thus also avoided that
The radiation risk of operating personnel.
For device embodiment, because it corresponds essentially to embodiment of the method, so related part is referring to method reality
Apply the part explanation of example.Device embodiment described above is only schematical, wherein described as separating component
The unit of explanation can be or may not be physically separate, and the part shown as unit can be or can also
It is not physical location, you can with positioned at a place, or can also be distributed on multiple NEs.Can be according to reality
Selection some or all of module therein is needed to realize the purpose of application scheme.Those of ordinary skill in the art are not paying
In the case of going out creative work, you can to understand and implement.
The preferred embodiment of the application is the foregoing is only, is not used to limit the application, all essences in the application
Within god and principle, any modification, equivalent substitution and improvements done etc. should be included within the scope of the application protection.
Claims (15)
1. a kind of image rebuilding method, it is characterised in that including：
Determine the crystal efficiency factor and geometrical factor of the single crystal of crystal centering, wherein, the crystal is to being crystalline substance in PET device
Crystal pair on body ring；
The crystal efficiency factor and geometrical factor according to the single crystal of crystal centering determine the sensitivity of the crystal pair；
Obtain the data to scanning patient by the crystal；
The data are corrected using the sensitivity of the crystal pair；
Image reconstruction is carried out according to the data after correction.
2. method according to claim 1, it is characterised in that the crystal efficiency of the single crystal of determination crystal centering because
Son and geometrical factor, including：
Collection crystal meets event to upper multiple backgrounds；
The multiple background is met into event and is divided into that first kind background meets event and Equations of The Second Kind background meets event；
Determine that first kind background meets the first crystal efficiency factor of event, and Equations of The Second Kind background meets the second crystal of event
Efficiency factor；
Meet event to the first kind background using the first crystal efficiency factor to be corrected, the first kind after being corrected
Background meets event, and meets event using Equations of The Second Kind background described in the second crystal efficiency factor pair and be corrected, and obtains
Equations of The Second Kind background meets event after to correction；
Meet the first kind background after upper correction event using each pair crystal and meet sum of events with Equations of The Second Kind background, determine institute
Crystal is stated to corresponding first geometrical factor of upper single crystal and the second geometrical factor.
3. method according to claim 2, it is characterised in that the multiple background is met into event and is divided into first kind sheet
Bottom meets event and Equations of The Second Kind background meets event and includes：
The multiple background met into event according to energy threshold it is divided into first kind background and meets event and Equations of The Second Kind background and accords with
Conjunction event.
4. method according to claim 2, it is characterised in that the determination first kind background meets the first crystal of event
Efficiency factor, and Equations of The Second Kind background meets the second crystal efficiency factor of event, including：
The first count totals and the second background that statistics first kind background meets event meet the second count totals of event；
According to first count totals and the second count totals using fan-beam algorithm calculate respectively first crystal efficiency factor and
The second crystal efficiency factor.
5. method according to claim 2, it is characterised in that using the first crystal efficiency factor to the first kind
Background meets event and is corrected, and first kind background meets event after being corrected, and using second crystal efficiency because
Son meets event and is corrected to the Equations of The Second Kind background, and Equations of The Second Kind background meets event after being corrected, including：
The first crystal efficiency factor is multiplied by the first kind background and meets event, the first kind background symbol after being corrected
Conjunction event, and the second crystal efficiency factor is multiplied by the Equations of The Second Kind background meets event, after being corrected second
Class background meets event.
6. method according to claim 2, it is characterised in that the utilization each pair crystal is to the first kind sheet after upper correction
Bottom meets event and meets sum of events with Equations of The Second Kind background, and the first geometrical factor and the second geometrical factor are calculated respectively, including：
Event and Equations of The Second Kind background are met upper first kind background according to each pair crystal after correction and meets sum of events, using returning
One changes algorithm calculates first geometrical factor of the crystal to a upper crystal；And
Event and Equations of The Second Kind background are met upper first kind background according to each pair crystal after correction and meets sum of events, using returning
One changes algorithm calculates second geometrical factor of the crystal to upper another crystal.
7. the method according to any one of claim 2 to 6, it is characterised in that the crystal according to the single crystal
Efficiency factor and geometrical factor determine the sensitivity of the crystal pair, including：
The first crystal efficiency factor, the second crystal efficiency factor, the first geometrical factor and the first geometrical factor are distinguished into phase
Multiply, obtain the sensitivity of crystal pair.
8. a kind of equipment for reconstructing image, it is characterised in that including：
First determining unit, the crystal efficiency factor and geometrical factor for determining the single crystal of crystal centering, wherein, the crystalline substance
Body is to being the crystal pair in crystal rings in PET device；
Second determining unit, the crystal efficiency factor and geometrical factor according to the single crystal of crystal centering determine the crystal
To sensitivity；
Acquiring unit, for obtaining the data by the crystal to scanning patient；
The data are corrected by correction unit for the sensitivity using the crystal pair；
Reconstruction unit, for carrying out image reconstruction according to the data after the correction unit correction.
9. device according to claim 8, it is characterised in that first determining unit includes：
Upper multiple backgrounds are met event by collecting unit for gathering crystal；
Division unit, for by the multiple background meet event be divided into first kind background meet event and Equations of The Second Kind background symbol
Conjunction event；
Efficiency factor determining unit, for determining that first kind background meets the first crystal efficiency factor of event, and Equations of The Second Kind
Background meets the second crystal efficiency factor of event；
Event correction unit, school is carried out for meeting event to the first kind background using the first crystal efficiency factor
Just, first kind background meets event after being corrected, and using Equations of The Second Kind background described in the second crystal efficiency factor pair
Meet event to be corrected, Equations of The Second Kind background meets event after being corrected；
Geometrical factor determining unit, for meeting the first kind background after upper correction event and Equations of The Second Kind sheet using each pair crystal
Bottom meets sum of events, determines the crystal to corresponding first geometrical factor of upper single crystal and the second geometrical factor.
10. device according to claim 8, it is characterised in that
The division unit, first kind background symbol is divided into specifically for the multiple background is met into event according to energy threshold
Conjunction event and Equations of The Second Kind background meet event.
11. devices according to claim 8, it is characterised in that the efficiency factor determining unit includes：
Statistic unit, the first count totals and the second background that event is met for counting first kind background meet the second of event
Count totals；
Computing unit, calculates first crystal and imitates respectively according to first count totals and the second count totals using fan-beam algorithm
The rate factor and the second crystal efficiency factor.
12. devices according to claim 8, it is characterised in that the event correction unit includes：
First correction subelement, event is met for the first crystal efficiency factor to be multiplied by into the first kind background, is obtained
First kind background after correction meets event；
Second correction subelement, event is met for the second crystal efficiency factor to be multiplied by into the Equations of The Second Kind background, is obtained
Equations of The Second Kind background after correction meets event.
13. devices according to claim 8, it is characterised in that the geometrical factor determining unit includes：
First determination subelement, for meeting the upper first kind background event and Equations of The Second Kind background according to each pair crystal after correction
Meet sum of events, first geometrical factor of the crystal to a upper crystal is calculated using normalization algorithm；
Second determination subelement, for meeting the upper first kind background event and Equations of The Second Kind background according to each pair crystal after correction
Meet sum of events, second geometrical factor of the crystal to upper another crystal is calculated using normalization algorithm.
14. device according to any one of claim 9 to 13, it is characterised in that second determining unit, specifically for
The first crystal efficiency factor, the second crystal efficiency factor, the first geometrical factor and the first geometrical factor are multiplied respectively, are obtained
To the sensitivity of crystal pair.
A kind of 15. Medical Devices, it is characterised in that including：Processor；And for storing the processor-executable instruction
Memory；Wherein,
The processor is configured as：
Determine the crystal efficiency factor and geometrical factor of the single crystal of crystal centering, wherein, the crystal is to being crystalline substance in PET device
Crystal pair on body ring；
The crystal efficiency factor and geometrical factor according to the single crystal of crystal centering determine the sensitivity of the crystal pair；
Obtain the data to scanning patient by the crystal；
The data are corrected using the sensitivity of the crystal pair；
Image reconstruction is carried out according to the data after correction.
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