CN106823029B - A kind of Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of the non-isometric splitterr vanes structure of band - Google Patents

A kind of Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of the non-isometric splitterr vanes structure of band Download PDF

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Publication number
CN106823029B
CN106823029B CN201710049861.2A CN201710049861A CN106823029B CN 106823029 B CN106823029 B CN 106823029B CN 201710049861 A CN201710049861 A CN 201710049861A CN 106823029 B CN106823029 B CN 106823029B
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splitterr vanes
linear leaf
short
isometric
micro
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CN106823029A (en
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谭建平
喻哲钦
王带领
程立志
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Central South University
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Central South University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20Type thereof
    • A61M60/205Non-positive displacement blood pumps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10Location thereof with respect to the patient's body
    • A61M60/122Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/148Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40Details relating to driving
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80Constructional details other than related to driving
    • A61M60/802Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/818Bearings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/04General characteristics of the apparatus implanted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/12Blood circulatory system
    • A61M2210/125Heart

Abstract

The invention discloses a kind of Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of the non-isometric splitterr vanes structure of band, including pump case, pilot blade (2), impeller (5) and rear guide vane (8), the impeller (5) is equipped with two panels linear leaf (11), and the long shunt blade (12) and short splitterr vanes (13) that at least one is long and the other is short are equipped between the linear leaf described in every two panels (11).Axial length ratio K1=0.55~0.65 of the long shunt blade (12) and the linear leaf (11), axial length ratio K2=0.30~0.40 of the short splitterr vanes (13) and the linear leaf (11).The back side deflection 4 of the linear leaf (11) of the long shunt blade (12) and short splitterr vanes (13) Xiang Suoshu between the linear leaf (11)0~60.The present invention be it is a kind of not only guaranteed lower blood damage under sufficiently small implantation volume, but also be capable of providing it is enough pump blood flow and pressure the Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps with non-isometric splitterr vanes structure.

Description

A kind of Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of the non-isometric splitterr vanes structure of band
Technical field
The present invention relates to a kind of blood pump more particularly to a kind of Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of the non-isometric splitterr vanes structure of band.
Background technique
Artificial heart be it is a kind of treat the maximally efficient Medical Devices of middle and advanced stage heart failure disease, be used to replace completely or partially Enough blood flows and pressure are provided for human heart, to realize the normal blood circulation of human body.Blood pump is then artificial heart Realize that the most crucial component of pump blood, impeller make blood pump obtain enough energy, follow to reach human body by the rotation of high speed The pressure requirements of ring.
Blood pump has the performance indicator of two most criticals of hydraulic performance and hemolysis.Hydraulic performance refers to blood pump in design Under volume and operating condition, if the blood circulation of human body requirement of flow 5L/min and 13.3Kpa pressure can be reached.Hemolytic It can then refer to that blood after flowing through blood pump, is influenced and generate the situation of the broken damage generation haemolysis of haemocyte by blood pump.
Currently, the technical problem that the design and manufacture of blood pump are crucial there is two comparisons:
One, the volume of blood pump needs to be designed sufficiently small to reduce after implantation on the physiological influence of human normal, but non- The flow and pressure requirements of blood circulation of human body are extremely difficult under often small design volume.
Two, blood pump can need to improve its boosting capability by very high revolving speed to reach enough pump courage and uprightness, but But it can therefore cause haemocyte to be crushed due to excessively high flow field shear stress, eventually lead to and haemolysis occurs and jeopardizes implantation The normal physiological condition of person.
Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps is current one of more common blood pump design form both at home and abroad, but it equally exists pump It is hemorrhagic insufficient to be crushed the higher problem of damage with haemocyte.
Arrange that splitterr vanes are a kind of hemorrhagic energy of raising blood pump pump between the linear leaf of Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps impeller Effective means, but study and find that the structure will lead to blood pump and be obviously improved to hematoclasis;Especially splitterr vanes into Near mouth end, since logical circulation road is crossed in the excessive extruding of splitterr vanes, it may appear that an apparent shearing force region, and lead Cause the broken haemolysis of haemocyte.
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of under sufficiently small implantation volume, had both guaranteed lower blood Liquid damage, and it is capable of providing the Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps with non-isometric splitterr vanes structure of enough pump blood flow and pressure.
In order to solve the above technical problem, the present invention provides the Minisize axial streaming blood with non-isometric splitterr vanes structure Pump, including pump case, pilot blade, impeller and rear guide vane, the impeller are equipped with two panels linear leaf, come into leaves described in every two panels The long shunt blade and short splitterr vanes that at least one is long and the other is short are equipped between piece.
Axial length ratio K1=0.55~0.65 of the long shunt blade and the linear leaf, the short shunting Axial length ratio K2=0.30~0.40 of blade and the linear leaf.
The axial length ratio K1=0.6 of the long shunt blade and the linear leaf, the short splitterr vanes with The axial length ratio K2=0.35 of the linear leaf.
The back side of the long shunt blade and short splitterr vanes between the linear leaf 11 to the linear leaf 4 °~6 ° of deflection.
The back side lateral deviation of the long shunt blade and short splitterr vanes between the linear leaf to the linear leaf Turn 5 °.
The Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps with non-isometric splitterr vanes structure by adopting the above technical scheme is shunted in every two panels and is grown It arranges that the two panels of Length discrepancy shunts short blade between blade, makes the input ends of adjacent splitterr vanes not in same axial position, from And reducing influences the obstruction of normal liquid stream in input end in splitterr vanes, significantly reduces cutting in splitterr vanes input end Shearing stress size, to also reduce the possibility to hematoclasis.Meanwhile by inclined to splitterr vanes number, length and axial direction The multi-parameter simulation analysis for degree of setting preferably has obtained the splitterr vanes design parameter of peak performance.The pump blood of blood pump after optimization It from the point of view of hemolysis, both ensure that splitterr vanes to the promotion effect of blood pump performance, and in turn avoided it and haemocyte is generated Shear stress destroy.
In conclusion the present invention is a kind of under sufficiently small implantation volume, lower blood damage was not only guaranteed, but also can The Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps with non-isometric splitterr vanes structure of enough pump blood flow and pressure is provided.
Detailed description of the invention
Fig. 1 is the tomograph for being the Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of the invention with non-isometric splitterr vanes.
Fig. 2 is the two-dimensional structure figure of the Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of the invention with non-isometric splitterr vanes.
Fig. 3 is Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps generally with isometric splitterr vanes and the present invention with the miniature of non-isometric splitterr vanes The haemolysis of axial blood pump impeller wheel portion estimates performance chart.
Fig. 4 is for the hydraulic performance curve graph of different splitterr vanes design form blood pumps.
It is as shown in the figure: 1- pump case front sleeve;2- pilot blade;3- bearing;4- central spindle;5- impeller;6- pump case middle sleeve;7- is forever Magnet;8- rear guide vane;The shaft end 9- locating piece;10- pump case after sleeve;11- linear leaf;12- long shunt blade;The short shunting leaf of 13- Piece.
Specific embodiment
The present invention will be further explained below with reference to the attached drawings.
Referring to Fig. 1 and Fig. 2, the Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of the non-isometric splitterr vanes structure of a kind of band, including by pump case protheca Cylinder 1, pump case middle sleeve 6 and 10 three parts of pump case after sleeve composition pump case, pilot blade 2, impeller 5, rear guide vane 8, permanent magnet 7, Central spindle 4, bearing 3 and shaft end locating piece 9, pilot blade 2 and rear guide vane 8 are nonrotational part, and fixation is clamped on the inner wall of pump case.Before Guide vane 2 and rear guide vane 8 guarantee the axial gap of 1mm with impeller 5 respectively.In order to guarantee enough intensity and preferable material parent blood Property, pilot blade 2, rear guide vane 8 and impeller 5 are all made of titanium alloy material.Central spindle 4 is fixed with 7 adhesion of permanent magnet for driving, leaf Wheel 5 is fixed with 7 adhesion of permanent magnet, is rotated under the action of outer Magnetic driving with the design speed of 8000r/min.Impeller 5 and pump case Inner wall between guarantee the gap of 1mm, with pump case any contact does not occur for blade 5 when rotation.The shaft part locating piece 9 at both ends with The end of central spindle 4 contacts, and central spindle 4, bearing 3 and shaft end locating piece 9 are all made of ceramic material, has the longevity compared with ordinary metallic material The feature that life is long, coefficient of friction is low and non-deformability is stronger.
As depicted in figs. 1 and 2, impeller 5 is equipped with two panels linear leaf 11, has what one is long and the other is short between every two panels linear leaf 11 Long shunt blade 12 and short splitterr vanes 13.Linear leaf 11, long shunt blade 12 and short splitterr vanes 13 are both secured to impeller 5 On.From principle, the very few splitterr vanes that can reduce of splitterr vanes number are to the improvement result of performance;But splitterr vanes number excessively then can It squeezes the area of passage of runner and influences blood pump performance.The method analyzed using Fluid Mechanics Computation, obtains optimal shunting leaf Piece design method is each arrangement one is long and the other is short non-isometric two panels splitterr vanes, that is, long shunt leaf between every two panels linear leaf 11 Piece 12 and short splitterr vanes 13.
Define splitterr vanes axial length ratio K be the ratio between splitterr vanes axial length L 1 and 11 axial length L 2 of linear leaf, That is splitterr vanes axial length ratio K=L1/L2.From principle, splitterr vanes are too long to squeeze runner, hinder proper flow, mistake It is short, it is unable to reach the effect for promoting impeller performance.The method analyzed using Fluid Mechanics Computation, has obtained optimal shunting leaf Piece axial length ratio.According to design, axial length ratio K1=0.55~0.65 of long shunt blade 12 and linear leaf 11, short shunting Axial length ratio K2=0.30~0.40 of blade 13 and linear leaf 11.Preferably, according to design preferred long shunt blade 12 with Axial length the ratio K1=0.6, the axial length ratio K2=0.35 of short splitterr vanes 13 and linear leaf 11 of linear leaf 11.
The peripheral orientation polarization degree coefficient D for defining long shunt blade 12 and short splitterr vanes 13 is long shunt blade 12 and short shunting The angle that blade 13 is deflected to 11 back side of linear leaf.D=0 ° of expression long shunt blade 12 and short splitterr vanes 13 are evenly arranged It is hit exactly in runner, and the D the big, indicates more biases to 11 back side of linear leaf.From principle, it is distributed in runner due to flowing It is uneven, general splitterr vanes to the linear leaf back side carry out it is a degree of deflection be conducive to improve impeller performance.Using meter The method of fluid operator Mechanics Simulation analysis, has obtained optimal splitterr vanes peripheral orientation polarization degree coefficient.D=4 ° of splitterr vanes~ 6 °, i.e. long shunt blade 12 between linear leaf 11 and short splitterr vanes 13 deflects 4 °~6 ° to the back side of linear leaf 11.It is preferred that Ground, D=5 ° of splitterr vanes, the i.e. back side lateral deviation of long shunt blade 12 between linear leaf 11 and short splitterr vanes 13 to linear leaf 11 Turn 5 °.
As shown in figure 3, for the Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps generally with isometric splitterr vanes with the present invention with non-isometric shunting leaf The haemolysis of the Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps impeller wheel portion of piece estimates performance chart.Abscissa is blood cells flow through blood pump leaf in Fig. 3 The time of wheel, ordinate are the shear stress scalar mean values for generating haemolysis and destroying.From the point of view of hemolysis estimation results, the present invention Non-isometric long shunt blade 12 and short splitterr vanes 13 in blood cells flow this period of the 0.055s-0.08s through impeller 5 Significantly reduce the shear stress size to hematoclasis;And the damage accumulation value of haemocyte is calculated, have non-isometric The haemolysis discreet value of the impeller 5 of long shunt blade 12 and short splitterr vanes 13 is 0.00522, i.e., will by the haemocyte of impeller 5 There is 0.522% damage ratio, the impeller discreet value of relatively general isometric splitterr vanes reduces 20.6%, therefore thinks that the invention has The hemolysis for improving Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of effect is horizontal.
As shown in figure 4, being the hydraulic performance curve graph of different splitterr vanes design form blood pumps.Recognize from hydraulic performance analysis For the Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of the invention with non-isometric splitterr vanes structure has essentially identical with isometric splitterr vanes blood pump High performance level, the lift demand of 13.3KPa can be reached under the design speed of 8000r/min;Compared with no splitterr vanes Blood pump has apparent performance advantage.
The hemolysis and hydraulic performance of complex chart 3 and Fig. 4 are analyzed, it is believed that a kind of non-isometric shunting of band proposed by the present invention The Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of blade construction both ensure that splitterr vanes acted on the raising of performance, have more outstanding pump courage and uprightness energy It is horizontal;Meanwhile non-isometric splitterr vanes design form in turn avoid because excessive compression flow field and bring haemocyte is molten Blood damage, it is horizontal with comprehensive performance optimal in different splitterr vanes design forms.Existing axial-flow type Small blood pump impeller is equal It is to use the isometric splitterr vanes of multi-disc, or do not use the structure design form of splitterr vanes.But its problem is: multi-disc is isometric Splitterr vanes can be due to influencing blood flow in its entrance location excessive compression, and it is broken to generate shearing force haemocyte Error area causes serious haemolysis to destroy damage.Axial flow blood pump impeller without arranging splitterr vanes, although it is right to can be avoided its The damage of haemocyte, but be difficult flow needed for reaching blood circulation of human body in reasonable blood pump volume, the range of speeds and Pressure requirement.
The present invention arranges the short splitterr vanes of the long shunt blade 12 of Length discrepancy between the linear leaf 11 that every two panels shunts 13, make the input end of adjacent long shunt blade 12 and short splitterr vanes 13 not in same axial position, to reduce long point Flowing blade 12 and short splitterr vanes 13 influences the obstruction of normal liquid stream in input end, significantly reduces in 12 He of long shunt blade The shear stress size of the input end of short splitterr vanes 13, to also reduce the possibility to hematoclasis.Meanwhile by right The multi-parameter simulation analysis of splitterr vanes number, length and axialy offset degree has preferably obtained the splitterr vanes design of peak performance Parameter.After optimization from the point of view of the pump blood and hemolysis of blood pump, both ensure that splitterr vanes to the promotion effect of blood pump performance, It is in turn avoided to destroy the shear stress that haemocyte generates.

Claims (5)

1. a kind of Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of the non-isometric splitterr vanes structure of band, including pump case, pilot blade (2), impeller (5) and after Guide vane (8), the impeller (5) be equipped with two panels linear leaf (11), it is characterized in that: the linear leaf described in every two panels (11) it Between be equipped with the long shunt blade (12) and short splitterr vanes (13) that one is long and the other is short.
2. the Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of the non-isometric splitterr vanes structure of band according to claim 1, it is characterized in that: described Axial length ratio K1=0.55~0.65 of long shunt blade (12) and the linear leaf (11), the short splitterr vanes (13) with axial length ratio K2=0.30~0.40 of the linear leaf (11).
3. the Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of the non-isometric splitterr vanes structure of band according to claim 1, it is characterized in that: described The axial length ratio K1=0.6 of long shunt blade (12) and the linear leaf (11), the short splitterr vanes (13) and institute The axial length ratio K2=0.35 for the linear leaf (11) stated.
4. the Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of the non-isometric splitterr vanes structure of band according to claim 1 or 2, it is characterized in that: institute The back of the linear leaf (11) of the long shunt blade (12) and short splitterr vanes (13) Xiang Suoshu between the linear leaf (11) stated Surface side deflects 4 °~6 °.
5. the Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of the non-isometric splitterr vanes structure of band according to claim 1 or 2, it is characterized in that: institute The back of the linear leaf (11) of the long shunt blade (12) and short splitterr vanes (13) Xiang Suoshu between the linear leaf (11) stated Surface side deflects 5 °.
CN201710049861.2A 2017-01-23 2017-01-23 A kind of Computational Fluid Dynamics Analysis of Micro-Axial Blood Pumps of the non-isometric splitterr vanes structure of band Active CN106823029B (en)

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