CN106820156A - A kind of probiotic composition of regulating intestinal canal flora health - Google Patents

A kind of probiotic composition of regulating intestinal canal flora health Download PDF

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Publication number
CN106820156A
CN106820156A CN201710086798.XA CN201710086798A CN106820156A CN 106820156 A CN106820156 A CN 106820156A CN 201710086798 A CN201710086798 A CN 201710086798A CN 106820156 A CN106820156 A CN 106820156A
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cfu
lactobacillus
bifidobacterium
parts
probiotic composition
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CN201710086798.XA
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周新富
黄轲
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Fujian Kang Shi Mei Biotechnology Co Ltd
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Fujian Kang Shi Mei Biotechnology Co Ltd
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Priority to CN201710086798.XA priority Critical patent/CN106820156A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The present invention provide it is a kind of comprising lactoferrin, inulin, bromelain, Radish extract comprehensive probiotic products, rich in the beneficial bacteria of intestinal tract such as lactobacillus acidophilus, bifidobacterium infantis, bifidobacterium longum, bifidobacterium breve, bifidobacterium bifidum, Lactobacillus rhamnosus, lactobacillus bulgaricus, Lactobacillus plantarum, Lactobacillus casei, lactobacillus paracasei, streptococcus thermophilus in the product;And the active principles such as lactoferrin, inulin and bromelain, Radish extract are added in the present invention, and be conducive to colonizing for beneficial bacteria of intestinal tract, it is beneficial to the foundation of healthy gut flora and maintains, the composition also has anti-inflammatory and immunoregulation effect.

Description

A kind of probiotic composition of regulating intestinal canal flora health
Technical field
The invention belongs to fermented food field, and in particular to a kind of probiotic composition of regulating intestinal canal flora health.
Background technology
Gut flora provides nutrition, regulation metabolism, the development of regulation and control gut epithelium and induction congenital immunity, its work(for human body " organ " that can be important equivalent to the one of human body, the balance for destroying gut flora be exactly the health for damaging people.
Since starting human microbial's group plan HMP from the U.S. in 2008, by a series of big action of microorganism fields, Current research analyzes the micro organism quantity and structure of 18 positions of the big main region of human body 5 using molecular biology method in the world Into, Healthy People body surface and the in vivo information of whole microorganism group are almost obtained, find micro- life of the body different parts to living away from home Thing group have significant effect.The Tiny ecosystem of human body is not only related to infectious diseases, and with the close phase of the development of chronic disease Close, research of the mankind to Tiny ecosystem changing conventional wisdom of the mankind to disease reason --- cured the disease steering from foeign element Human body microbial state treatment.
There is a growing awareness that the importance of gut flora microecological balance, probiotics is referred to as microbial food living Replenishers, it passes through to improve enteric microorganism so as to influence host health.But though viable bacteria content is rich in existing probiotic products Richness, but microorganism is difficult to be colonized in enteron aisle, so that it improves intestinal microecology effect being limited.Regulation intestines of the present invention The probiotic composition microorganism group of road flora health into it is abundant, rationally and be collocated with being adapted to inulin that enteric microorganism utilizes, The prebioticses such as oligosaccharides, and add lactoferrin and bromelain with certain antibacterial action, Radish extract isoreactivity Material, it is reasonable to be arranged in pairs or groups between each material composition, and considerably increase probiotics colonizes rate, can effectively maintain and/or recover intestines and be good for The common alimentary canal ecological disturbance problem that health and prevention are caused by pressure, inapt eating habit and antibiotic therapy. Effect with notable regulating intestinal canal flora health.
The content of the invention
For overcome existing probiotic products probiotics colonize rate it is low so as to cannot the effective healthy problem of regulating intestinal canal flora, The invention provides a kind of probiotic composition of regulating intestinal canal flora health;The probiotic composition can effectively maintain and/or Recover gut health and prevention to be lost by the common alimentary canal ecology that pressure, inapt eating habit and antibiotic therapy cause Tune problem.Effect with notable regulating intestinal canal flora health.
To achieve the above object, the present invention is adopted the following technical scheme that:
A kind of probiotic composition of regulating intestinal canal flora health, including following raw material:Comprehensive probiotics 60-80 parts, Lactoferrin 0.1-3 parts, inulin 15-20 parts, bromelain 1-3 parts, Radish extract 1-3 parts, oligosaccharides 2-15 parts.
Wherein, the comprehensive probiotic group turns into:Lactobacillus acidophilus, bifidobacterium infantis, bifidobacterium longum, short bifid bar Bacterium, bifidobacterium bifidum, Lactobacillus rhamnosus, lactobacillus bulgaricus, Lactobacillus plantarum, Lactobacillus casei, secondary cheese breast bar Bacterium, streptococcus thermophilus.
The oligosaccharides is one or more in manna oligosacchride, manna oligosaccharide, shitosan or fructose oligosaccharides.
The number of viable of the probiotic composition is:Lactobacillus acidophilus 1010-1011CFU/g, bifidobacterium infantis 1010- 1011CFU/g, bifidobacterium longum 109-1010CFU/g, bifidobacterium breve 109-1010CFU/g, bifidobacterium bifidum 109- 1010CFU/g, Lactobacillus rhamnosus 1010-1011CFU/g, lactobacillus bulgaricus 1010-1011CFU/g, Lactobacillus plantarum 1010- 1011CFU/g, Lactobacillus casei 109-1010CFU/g, lactobacillus paracasei 109-1010CFU/g, streptococcus thermophilus 108- 109CFU/g。
The preparation method of the Radish extract is as follows:Broken squeezing, squeezing are carried out after fresh ternip is cleaned into stripping and slicing During be continuously added the white turnip juice squeezed out, after 0.2 μm of membrane filtration freeze obtain Radish extract.
Lactoferrin:Lactoferrin is a kind of important non-heme combination glycoprotein, neutrophil leucocyte particle in milk In have bactericidal activity monomeric glycoprotein.Its transhipment for not being only involved in iron, and with broad-spectrum antiseptic, anti-oxidant, anticancer, tune The section powerful biological function such as immune system, it is considered to be the food of a kind of novel antibacterial, cancer therapy drug and great exploitation potential and Feed addictive.The dietary proteins source that amino acid is can not only be used in probiotic products is made an addition to, the life of iron is also beneficial to Thing is utilized.
Inulin:Inulin is the form of another energy storage of the plant in addition to starch, and it is contained in cell with colloid form In plasm;Inulin can be hydrolyzed into the enzyme for all lacking in fructose, but humans and animals body and decomposing inulin by inulinase.Therefore inulin Will not be absorbed by human body in vivo, but can be metabolized by human flora after it enters large intestine, research shows, inulin can stimulate enteron aisle The beneficial bacteriums such as Bifidobacterium are largely bred, and improve Bifidobacterium vigor, suppress cause a disease bacteria growing and breeding, maintain gut flora to put down Weighing apparatus;Additionally, being that microorganism species and gas production are improved after inulin ferments in colon, so as to promote intestines peristalsis, shorten excrement In the residence time of colon, make hyperlocomotion, reduce the moisture absorption time, increased stool weight, effective Constipation; Also increase the excretion of excrement simultaneously, be that the carcinogen in enteron aisle is also diluted.
Bromelain:Bromelain is the proteolytic enzyme being present in pineapple plant, is various different moleculars The albumen enzyme system group of amount and molecular structure;It also contains phosphate, peroxidase, cellulose in addition to containing protease Enzyme etc..Animal experiment and human trial show that bromelain is absorbed profit with 40% ratio in animal intestinal tract with prototype With.Further, since there is biologically active peptide in bromelain, therefore it can suppress the growth of human body bacterium.
Radish extract:Radish extract can improve superoxide dismutase activity, reduce mda content and can The peroxide for repairing intestinal mucosa is damaged, and has protective effect to intestinal mucosa.
The advantage of the invention is that:The probiotic composition microorganism group of regulating intestinal canal flora of the present invention health into It is abundant, rationally and be collocated with being adapted to the prebioticses such as inulin, oligosaccharides that enteric microorganism utilizes, and add and make with certain antibacterial Lactoferrin and bromelain, Radish extract isoreactivity material, it is reasonable to be arranged in pairs or groups between each material composition, increases greatly Added probiotics colonizes rate, can effectively maintain and/or recover gut health and prevention by pressure, inapt eating habit and The common alimentary canal ecological disturbance problem that antibiotic therapy causes.Effect with notable regulating intestinal canal flora health.
Specific embodiment
Embodiment 1
A kind of probiotic composition of regulating intestinal canal flora health, including following raw material:68 parts of comprehensive probiotics, newborn iron 2 parts of albumen, 18 parts of inulin, 2 parts of bromelain, 2 parts of Radish extract, 8 parts of oligosaccharides.
Wherein, the comprehensive probiotic group turns into:Lactobacillus acidophilus, bifidobacterium infantis, bifidobacterium longum, short bifid bar Bacterium, bifidobacterium bifidum, Lactobacillus rhamnosus, lactobacillus bulgaricus, Lactobacillus plantarum, Lactobacillus casei, secondary cheese breast bar Bacterium, streptococcus thermophilus.
The oligosaccharides is manna oligosacchride.
The number of viable of the probiotic composition is:Lactobacillus acidophilus 1011CFU/g, bifidobacterium infantis 1011CFU/ G, bifidobacterium longum 1010CFU/g, bifidobacterium breve 1010CFU/g, bifidobacterium bifidum 1010CFU/g, Lactobacillus rhamnosus 1011CFU/g, lactobacillus bulgaricus 1011CFU/g, Lactobacillus plantarum 1011CFU/g, Lactobacillus casei 1010CFU/g, secondary cheese Lactobacillus 1010CFU/g, streptococcus thermophilus 109CFU/g。
The preparation method of the Radish extract is as follows:Broken squeezing, squeezing are carried out after fresh ternip is cleaned into stripping and slicing During be continuously added the white turnip juice squeezed out, after 0.2 μm of membrane filtration freeze obtain Radish extract.
Embodiment 2
A kind of probiotic composition of regulating intestinal canal flora health, including following raw material:60 parts of comprehensive probiotics, newborn iron 3 parts of albumen, 20 parts of inulin, 3 parts of bromelain, 3 parts of Radish extract, 11 parts of oligosaccharides.
Wherein, the comprehensive probiotic group turns into:Lactobacillus acidophilus, bifidobacterium infantis, bifidobacterium longum, short bifid bar Bacterium, bifidobacterium bifidum, Lactobacillus rhamnosus, lactobacillus bulgaricus, Lactobacillus plantarum, Lactobacillus casei, secondary cheese breast bar Bacterium, streptococcus thermophilus.
The oligosaccharides is manna oligosacchride, manna oligosaccharide, shitosan and each 2 parts of fructose oligosaccharides.
The number of viable of the probiotic composition is:Lactobacillus acidophilus 1010CFU/g, bifidobacterium infantis 1010CFU/ G, bifidobacterium longum 109CFU/g, bifidobacterium breve 109CFU/g, bifidobacterium bifidum 109CFU/g, Lactobacillus rhamnosus 1010CFU/g, lactobacillus bulgaricus 1010CFU/g, Lactobacillus plantarum 1010CFU/g, Lactobacillus casei 109CFU/g, secondary cheese Lactobacillus 109CFU/g, streptococcus thermophilus 108CFU/g。
The preparation method of the Radish extract is as follows:Broken squeezing, squeezing are carried out after fresh ternip is cleaned into stripping and slicing During be continuously added the white turnip juice squeezed out, after 0.2 μm of membrane filtration freeze obtain Radish extract.
Embodiment 3
A kind of probiotic composition of regulating intestinal canal flora health, including following raw material:80 parts of comprehensive probiotics, newborn iron 0.1 part of albumen, 15 parts of inulin, 1 part of bromelain, 1 part of Radish extract, 2.9 parts of oligosaccharides.
Wherein, the comprehensive probiotic group turns into:Lactobacillus acidophilus, bifidobacterium infantis, bifidobacterium longum, short bifid bar Bacterium, bifidobacterium bifidum, Lactobacillus rhamnosus, lactobacillus bulgaricus, Lactobacillus plantarum, Lactobacillus casei, secondary cheese breast bar Bacterium, streptococcus thermophilus.
The oligosaccharides is manna oligosacchride and each 1.45 parts of shitosan.
The number of viable of the probiotic composition is:Lactobacillus acidophilus 1011CFU/g, bifidobacterium infantis 1010CFU/ G, bifidobacterium longum 109CFU/g, bifidobacterium breve 109CFU/g, bifidobacterium bifidum 109CFU/g, Lactobacillus rhamnosus 1011CFU/g, lactobacillus bulgaricus 1011CFU/g, Lactobacillus plantarum 1011CFU/g, Lactobacillus casei 1010CFU/g, secondary cheese Lactobacillus 109CFU/g, streptococcus thermophilus 109CFU/g。
The preparation method of the Radish extract is as follows:Broken squeezing, squeezing are carried out after fresh ternip is cleaned into stripping and slicing During be continuously added the white turnip juice squeezed out, after 0.2 μm of membrane filtration freeze obtain Radish extract.
The foregoing is only presently preferred embodiments of the present invention, all impartial changes done according to scope of the present invention patent with Modification, should all belong to covering scope of the invention.

Claims (5)

1. the probiotic composition of a kind of regulating intestinal canal flora health, it is characterised in that:Including following raw material:Comprehensive benefit Raw bacterium 60-80 parts, lactoferrin 0.1-3 parts, inulin 15-20 parts, bromelain 1-3 parts, Radish extract 1-3 parts, oligosaccharides 2-15 parts.
2. the probiotic composition of a kind of regulating intestinal canal flora health according to claim 1, it is characterised in that:It is described comprehensive Closing probiotic group turns into:Lactobacillus acidophilus, bifidobacterium infantis, bifidobacterium longum, bifidobacterium breve, bifidobacterium bifidum, mouse Lee's sugar lactobacillus, lactobacillus bulgaricus, Lactobacillus plantarum, Lactobacillus casei, lactobacillus paracasei, streptococcus thermophilus.
3. a kind of probiotic composition of regulating intestinal canal flora health according to claim 1, it is characterised in that the widow Sugar is one or more in manna oligosacchride, manna oligosaccharide, shitosan or fructose oligosaccharides.
4. a kind of probiotic composition of regulating intestinal canal flora health according to claim 1 and 2, it is characterised in that institute The number of viable for stating probiotic composition is:Lactobacillus acidophilus 1010-1011CFU/g, bifidobacterium infantis 1010-1011CFU/g、 Bifidobacterium longum 109-1010CFU/g, bifidobacterium breve 109-1010CFU/g, bifidobacterium bifidum 109-1010CFU/g, rhamnose Lactobacillus 1010-1011CFU/g, lactobacillus bulgaricus 1010-1011CFU/g, Lactobacillus plantarum 1010-1011CFU/g, cheese breast Bacillus 109-1010CFU/g, lactobacillus paracasei 109-1010CFU/g, streptococcus thermophilus 108-109CFU/g。
5. the probiotic composition of a kind of regulating intestinal canal flora health according to claim 1, it is characterised in that described white The preparation method of Turnip extractive is as follows:Broken squeezing is carried out after fresh ternip is cleaned into stripping and slicing, is continuously added in expressing process The white turnip juice squeezed out, freezes after 0.2 μm of membrane filtration and obtains Radish extract.
CN201710086798.XA 2017-02-17 2017-02-17 A kind of probiotic composition of regulating intestinal canal flora health Pending CN106820156A (en)

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Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107455744A (en) * 2017-08-22 2017-12-12 绵阳市润土农业科技开发有限公司 A kind of fementative composition ferment and preparation method thereof in vivo
CN108208843A (en) * 2017-12-30 2018-06-29 广州润虹医药科技股份有限公司 A kind of health composition for adjusting intestinal flora and application thereof
CN108936679A (en) * 2018-08-29 2018-12-07 广东时代食品与生命健康研究有限公司 A kind of compound intestinal health health care product
CN109123679A (en) * 2018-08-21 2019-01-04 卓源健康科技有限公司 A kind of lactic bacteria composition and preparation method thereof with adjusting intestinal flora function
CN109432333A (en) * 2018-10-11 2019-03-08 张军毅 A kind of synbiotic compound preparation and preparation method thereof for helping to alleviate no solid lesion hypertension symptom
WO2019049157A1 (en) * 2017-09-10 2019-03-14 Technion Research & Development Foundation Limited Composition and method for a prebiotic delivery system targeted to probiotic bacteria
CN110013490A (en) * 2018-01-09 2019-07-16 柯顺议 Probiotic composition and application thereof
CN110279118A (en) * 2019-06-14 2019-09-27 浙江大学宁波理工学院 A kind of compound probiotic composition, compound probiotic freeze-dried powder capsule and preparation method
CN111084386A (en) * 2020-02-28 2020-05-01 大连万众益生大健康有限公司 Probiotic supplement with function of improving intestinal tract
CN111557448A (en) * 2020-05-26 2020-08-21 深圳市东荣生物科技有限责任公司 Compound microbial preparation for enhancing metabolic function of human body
CN111758830A (en) * 2020-07-08 2020-10-13 天津蚓福生物科技开发有限公司 Blood fat reducing antioxidant tabletting candy
CN113005067A (en) * 2021-03-31 2021-06-22 盐城维康生物科技有限公司 Multifunctional composite probiotic preparation and preparation method thereof
CN113491337A (en) * 2021-06-15 2021-10-12 合生元(广州)健康产品有限公司 Composition for regulating infant intestinal tract short-chain fatty acid metabolism and application thereof
CN113615838A (en) * 2020-05-06 2021-11-09 宏浚实业有限公司 Probiotic complexes for improving gastrointestinal health
CN114831286A (en) * 2022-05-30 2022-08-02 天津小薇生物科技有限公司 Composition with constipation relieving function and preparation method thereof
CN115054617A (en) * 2022-07-07 2022-09-16 中国人民解放军陆军特色医学中心 Probiotic composition for treating diarrhea-predominant irritable bowel syndrome and application thereof
CN115989836A (en) * 2022-11-29 2023-04-21 黑龙江飞鹤乳业有限公司 Nutritional composition containing lactoferrin and probiotics, food and application
WO2024055983A1 (en) * 2022-09-14 2024-03-21 南京纽邦生物科技有限公司 Composition of pumpkin seed protein and use thereof

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Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107455744A (en) * 2017-08-22 2017-12-12 绵阳市润土农业科技开发有限公司 A kind of fementative composition ferment and preparation method thereof in vivo
WO2019049157A1 (en) * 2017-09-10 2019-03-14 Technion Research & Development Foundation Limited Composition and method for a prebiotic delivery system targeted to probiotic bacteria
CN108208843A (en) * 2017-12-30 2018-06-29 广州润虹医药科技股份有限公司 A kind of health composition for adjusting intestinal flora and application thereof
CN110013490A (en) * 2018-01-09 2019-07-16 柯顺议 Probiotic composition and application thereof
CN109123679A (en) * 2018-08-21 2019-01-04 卓源健康科技有限公司 A kind of lactic bacteria composition and preparation method thereof with adjusting intestinal flora function
CN108936679A (en) * 2018-08-29 2018-12-07 广东时代食品与生命健康研究有限公司 A kind of compound intestinal health health care product
CN109432333A (en) * 2018-10-11 2019-03-08 张军毅 A kind of synbiotic compound preparation and preparation method thereof for helping to alleviate no solid lesion hypertension symptom
CN110279118A (en) * 2019-06-14 2019-09-27 浙江大学宁波理工学院 A kind of compound probiotic composition, compound probiotic freeze-dried powder capsule and preparation method
CN111084386A (en) * 2020-02-28 2020-05-01 大连万众益生大健康有限公司 Probiotic supplement with function of improving intestinal tract
CN113615838A (en) * 2020-05-06 2021-11-09 宏浚实业有限公司 Probiotic complexes for improving gastrointestinal health
CN111557448A (en) * 2020-05-26 2020-08-21 深圳市东荣生物科技有限责任公司 Compound microbial preparation for enhancing metabolic function of human body
CN111758830A (en) * 2020-07-08 2020-10-13 天津蚓福生物科技开发有限公司 Blood fat reducing antioxidant tabletting candy
CN111758830B (en) * 2020-07-08 2022-03-29 天津蚓福生物科技开发有限公司 Blood fat reducing antioxidant tabletting candy
CN113005067A (en) * 2021-03-31 2021-06-22 盐城维康生物科技有限公司 Multifunctional composite probiotic preparation and preparation method thereof
CN113491337A (en) * 2021-06-15 2021-10-12 合生元(广州)健康产品有限公司 Composition for regulating infant intestinal tract short-chain fatty acid metabolism and application thereof
CN114831286A (en) * 2022-05-30 2022-08-02 天津小薇生物科技有限公司 Composition with constipation relieving function and preparation method thereof
CN114831286B (en) * 2022-05-30 2023-09-26 天津小薇生物科技有限公司 Composition with constipation relieving function and preparation method thereof
CN115054617A (en) * 2022-07-07 2022-09-16 中国人民解放军陆军特色医学中心 Probiotic composition for treating diarrhea-predominant irritable bowel syndrome and application thereof
CN115054617B (en) * 2022-07-07 2023-12-22 中国人民解放军陆军特色医学中心 Probiotic composition for treating diarrhea type irritable bowel syndrome and application thereof
WO2024055983A1 (en) * 2022-09-14 2024-03-21 南京纽邦生物科技有限公司 Composition of pumpkin seed protein and use thereof
CN115989836A (en) * 2022-11-29 2023-04-21 黑龙江飞鹤乳业有限公司 Nutritional composition containing lactoferrin and probiotics, food and application

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