CN106750406A - The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel - Google Patents

The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel Download PDF

Info

Publication number
CN106750406A
CN106750406A CN201611127248.XA CN201611127248A CN106750406A CN 106750406 A CN106750406 A CN 106750406A CN 201611127248 A CN201611127248 A CN 201611127248A CN 106750406 A CN106750406 A CN 106750406A
Authority
CN
China
Prior art keywords
component
weight
aqueous solution
gel
deionized water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201611127248.XA
Other languages
Chinese (zh)
Inventor
朱明�
孙凯
江燕妮
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sichuan Normal University
Original Assignee
Sichuan Normal University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sichuan Normal University filed Critical Sichuan Normal University
Priority to CN201611127248.XA priority Critical patent/CN106750406A/en
Publication of CN106750406A publication Critical patent/CN106750406A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
    • C08J3/246—Intercrosslinking of at least two polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10—Esters
    • C08F222/12—Esters of phenols or saturated alcohols
    • C08F222/14—Esters having no free carboxylic acid groups, e.g. dialkyl maleates or fumarates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C08F283/06—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polyethers, polyoxymethylenes or polyacetals
    • C08F283/065—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polyethers, polyoxymethylenes or polyacetals on to unsaturated polyethers, polyoxymethylenes or polyacetals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L35/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical, and containing at least one other carboxyl radical in the molecule, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L35/02—Homopolymers or copolymers of esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10—Esters
    • C08F222/12—Esters of phenols or saturated alcohols
    • C08F222/14—Esters having no free carboxylic acid groups, e.g. dialkyl maleates or fumarates
    • C08F222/145—Esters having no free carboxylic acid groups, e.g. dialkyl maleates or fumarates the ester chains containing seven or more carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2335/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical, and containing at least one other carboxyl radical in the molecule, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Derivatives of such polymers
    • C08J2335/02—Characterised by the use of homopolymers or copolymers of esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2451/00—Characterised by the use of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives of such polymers
    • C08J2451/08—Characterised by the use of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives of such polymers grafted on to macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/04—Polymer mixtures characterised by other features containing interpenetrating networks

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to a kind of preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel.The method is to make comonomer with MethacryloyloxyethylTrimethyl Trimethyl Ammonium Chloride, dimethylaminoethyl acrylate, forulic acid, PEGDMA-400 makees crosslinking agent, and potassium peroxydisulfate sodium hydrogensulfite makees initiator and carry out copolymerization in deionized water to obtain organic amphiprotic copolymerized macromolecule first network gel；The first network gel is swelling in the aqueous solution that itaconic acid, glycerine, methacrylic acid oxygen ethyl trimellitic anhydride ester, dimethacrylate cyclohexanediol ester and deionized water are prepared, monomer, crosslinking agent in the aqueous solution are copolymerized conjunction, esterification through the effect of potassium peroxydisulfate, pyridoxine hydrochloride, finally obtain organic amphiprotic copolymerized macromolecule interpenetrating networks gel.

Description

The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
Technical field
The present invention relates to a kind of preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel.
Background technology
Gel is a kind of special dispersion, and high-polymer molecular or colloidal solid interconnect, and to form three dimensions netted Structure, can absorb substantial amounts of water-swellable and water insoluble, and definite shape can be kept in water, have solid and liquid duality concurrently Matter.Macroscopically see, high-molecular gel has certain shape, applying certain external force can deform, can recover original after removal external force Shape, the viscoplasticity with solid；Seen on microcosmic, high-molecular gel has three-dimensional net structure water insoluble, three-dimensional network point Son can stretch in water, with liquid property.With soft, water content it is high and have the viscoelastic gel of rubber environmental protection, weaving, All many-sides such as building materials, petrochemical industry, food, agricultural gardening, daily cosmetics have and are widely applied.
Organism including humans is all high-molecular gel composition, mostly with electrical, such as protein, amino acid. Copolymerization Amphiphatic high polymer interpenetrating networks gel can obtain Protean specific performance, particularly height and contains with the change of copolymerization component The similitude of the electrical and organization of human body in water and molecule, good biocompatibility, environmental stimulus response is cured in biology The fields such as medicine controlled releasing, bio-sensing, the organizational project in medicine field have obtained some applications.
The problem that the preparation method of current organic amphiprotic copolymerized macromolecule interpenetrating networks gel is primarily present is monomer propylene The toxic articles of acid amides category " carcinogenic, aberration inducing, mutagenesis ", crosslinking agent N, N methylene diacrylamine toxicity is larger, and gel is deposited In unfavorable toxic effect；The interpenetrating networks gel stability that single crosslinking agent is formed is relatively low.Exploitation uses nontoxic or low toxicity Monomer, crosslinking agent carry out combined polymerization to reduce gel toxicity, forming multiple interpenetrating networks using compounding crosslinking agent improves gel The preparation method of the organic amphiprotic copolymerized macromolecule interpenetrating networks gel of stability has larger practical value.
The content of the invention
For the problem that the preparation method of current organic amphiprotic copolymerized macromolecule interpenetrating networks gel is present, mesh of the invention Be to provide it is a kind of use nontoxic or low-toxicity monomer, the crosslinking agent to carry out combined polymerization to reduce gel toxicity, use and compound crosslinking agent The preparation method that multiple interpenetrating networks improve the organic amphiprotic copolymerized macromolecule interpenetrating networks gel of gel stability is formed, it is special It is that in closed reactor component A and deionized water stirring can added to prepare the aqueous solution to levy, and the weight concentration for controlling component A is 28%~62%；After the completion of prepared by solution, relative degree of vacuum is evacuated to for -0.02MPa~-0.08MPa, be passed through nitrogen and recover anti- After answering device to normal pressure, add the aqueous solution prepared by B component and deionized water under agitation, the weight concentration of B component for 20%~ 40%；After the aqueous solution charging of B component terminates, 35 DEG C~50 DEG C are warming up to, add matched somebody with somebody by component C and deionized water under agitation The aqueous solution of system, the weight concentration of component C is 5%~15%；Control ph is 4~10, in 35 DEG C~50 DEG C constant temperature, continues to stir Reaction 2h~3.5h, obtains organic amphiprotic copolymerized macromolecule first network gel；Then cooled down, in the case where nitrogen is passed through, will The aqueous solution that first network gel input is prepared equipped with D components and deionized water can be swelling in closed reactor, D components Weight concentration is 1.8%~11%, by weight, first network gel:Weight ratio=1 of D component deionized water solutions:（95~ 155）, swelling 2h~6h；Add the aqueous solution prepared by component E and deionized water and continue swelling, the weight concentration of component E is 10%~20%, swelling 16 h~24 h；After the completion of swelling, 75 DEG C~95 DEG C are warming up to, control ph is 3~7,75 DEG C~95 DEG C constant temperature, reacts 4h~6h, obtains organic amphiprotic copolymerized macromolecule interpenetrating networks gel.The component A is by methacryloxypropyl Ethyl-trimethyl salmiac, dimethylaminoethyl acrylate, forulic acid composition, by the gauge of material, methylacryoyloxyethyl Trimethyl ammonium chloride:Dimethylaminoethyl acrylate:The ratio between amount of material of forulic acid=（0.5~1.2）:（0.3~1.6）: （0.4~1.1）；B component is PEGDMA-400, and number-average molecular weight is 2000~20000, its gross weight that feeds intake It is the 2.5%~11% of component A gross weight；Component C is made up of potassium peroxydisulfate-sodium hydrogensulfite, and its gross weight that feeds intake is total component A The 0.3%~1.8% of weight, by weight, potassium peroxydisulfate:Weight ratio=1 of sodium hydrogensulfite:（0.2~1.1）；D components by Itaconic acid, glycerine, methacrylic acid oxygen ethyl trimellitic anhydride ester and dimethacrylate cyclohexanediol ester composition, by material Gauge, itaconic acid:Glycerine:The ratio between amount of material of methacrylic acid oxygen ethyl trimellitic anhydride ester=（0.2~1.0）: （0.08~0.32）:（0.4~1.1）, by weight, dimethacrylate cyclohexanediol ester charged material weight is itaconic acid, the third three Alcohol, three kinds the 1.8%~5.5% of total monomer weight of methacrylic acid oxygen ethyl trimellitic anhydride ester；Component E is by potassium peroxydisulfate, pyrrole Alcohol hydrochloride of trembling is constituted, and potassium peroxydisulfate charged material weight is the 0.1%~1.2% of D component weights, pyridoxine hydrochloride charged material weight It is the 0.8%~5.6% of D component weights.
What technical method of the invention was realized in：Methylacryoyloxyethyl front three can be being prepared in closed reactor Ammonium chloride CH2=C(CH3)COO(CH2)2N(CH3)3Cl, dimethylaminoethyl acrylate CH2=CHCOO(C2H4)N(CH3)2, Ah Wei's acid (HO) (CH3O)C6H3The aqueous solution of CH=CHCOOH comonomers；After vacuumizing deoxidation, nitrogen protection is passed through, adds crosslinking The aqueous solution of agent PEGDMA-400；After intensification, redox initiator potassium peroxydisulfate-bisulfite is added Sodium K2S2O8-NaHSO3The aqueous solution, through trigger, combined polymerization chain propagation reaction, crosslinking agent PEGDMA-400 ginseng Crosslink reaction and form cross-linked network structure with copolyreaction and line style copolymerization macromolecular, through chain termination reaction, obtain organic Both sexes copolymerized macromolecule first network gel.Nitrogen protection is passed through, organic amphiprotic copolymerized macromolecule first network gel is in clothing health Sour CH2=C(COOH)CH2COOH, glycerine (HO) CH2CH(OH)CH2(OH), methacrylic acid oxygen ethyl trimellitic anhydride ester CH2 =C(CH3)COO(CH2)2OOCC6H3C2O3, dimethacrylate cyclohexanediol ester CH2=C(CH3)COO-(C6H10)-OOC(CH3)C It is swelling under the aqueous solution effect of=CH, add initiator potassium persulfate K2S2O8, catalyst pyridoxine hydrochloride (CH3) (HOCH2)2(HO)C5Continue swelling in the presence of the HNHCl aqueous solution, in swelling process, monomer, crosslinking agent in the aqueous solution, Initiator, catalyst enter into organic amphiprotic copolymerized macromolecule first network gel inside and are uniformly distributed；Through initiation, combined polymerization Chain propagation reaction forms line style copolymerization macromolecular, and crosslinking agent dimethacrylate cyclohexanediol ester participates in copolyreaction and line style is common Poly- macromolecular crosslinks reaction, forms cross-linked network structure, pyridoxine hydrochloride molecule of the catalysis with carboxylic group and band hydroxyl There is esterification in the molecule of base group, because glycerine to be formed with three OH groups by being reacted with the molecule with carboxylic group Cross-linked network structure；Further reaction, finally due to the chain termination and the completion of esterification of radical copolymerization macromolecular, shape Into organic amphiprotic copolymerized macromolecule interpenetrating networks gel.
Relative to art methods, outstanding advantages of the present invention are monomer methacryloxypropyl second used in technology of preparing Base trimethyl ammonium chloride, dimethylaminoethyl acrylate, methacrylic acid oxygen ethyl trimellitic anhydride ester and crosslinking agent dimethyl Acrylate diol ester low toxicity, monomer ferulic acid, itaconic acid and crosslinking agent PEGDMA-400, glycerine without Poison, reduces gel toxicity；The interpenetrating networks gel of preparation has radical crosslinking and esterification and crosslinking network structure, improves mutually Wear the stability of network gel；Preparation method is simple, reaction condition is gentle, be suitable for production, with good environmental benefit and warp Ji benefit.
Specific embodiment
Embodiment 1：124.5g MethacryloyloxyethylTrimethyl Trimethyl Ammonium Chlorides, 57.3g dimethylaminoethyl acrylates, 97.1g forulic acids and 650.7ml deionized waters are added to volume can be uniformly mixed in closed reactor for 2L, and this is water-soluble The weight concentration of liquid is 30%；Relative degree of vacuum -0.03MPa is evacuated to, nitrogen is then passed to and is recovered reactor to normal pressure, plus The number-average molecular weight for entering 8.37g be 3000 PEGDMA-400 and 31.5ml deionized waters prepare it is water-soluble Liquid, the weight concentration of the aqueous solution is 21%；Then heat to 37 DEG C, add 1.07g potassium peroxydisulfates, 0.32g sodium hydrogensulfites and The aqueous solution that 24ml deionized waters are prepared, the weight concentration of the aqueous solution is 5.5%, and in 37 DEG C of constant temperature, control ph is 4.5, after Continuous stirring reaction 2.3h, obtains organic amphiprotic copolymerized macromolecule first network gel；Then cooled down, in the case where nitrogen is passed through, Organic amphiprotic copolymerized macromolecule first network gel 95.04g input volumes can swelling, reaction in closed reactor for 15L's 39g itaconic acids, 9.2g glycerine, 138.1g methacrylic acid oxygen ethyl trimellitic anhydrides ester, 3.7g dimethyl propylenes are housed in device The aqueous solution that olefin(e) acid cyclohexanediol ester and 9314ml deionized waters are prepared, the weight concentration of the aqueous solution is 2%, and first network coagulates The weight of glue（95.04g）:The weight of the aqueous solution（9504.1g）=1:100, swelling 3h；Add 0.38g potassium peroxydisulfates, The aqueous solution that 1.9g pyridoxine hydrochlorides and 19.5ml deionized waters are prepared continues swelling, and the weight concentration of the aqueous solution is 10.5%, swelling 17h；77 DEG C are warming up to after the completion of swelling, control ph is 3.4, in 77 DEG C of isothermal reaction 4.3h, obtain organic Both sexes copolymerized macromolecule interpenetrating networks gel.The gel is water insoluble, can be swelling in water, gel swelling rate（ESR）=9758% （Deionized water）, gel swelling rate（ESR）=9636%（The NaCl aqueous solution of weight concentration 1%）.
Embodiment 2：228.2g MethacryloyloxyethylTrimethyl Trimethyl Ammonium Chlorides, 214.8g dimethylaminoethyl acrylates, 194.2g forulic acids and 424.8ml deionized waters are added to volume for 1L can be uniformly mixed in closed reactor, and this is water-soluble The weight concentration of liquid is 60%；Relative degree of vacuum -0.07MPa is evacuated to, nitrogen is then passed to and is recovered reactor to normal pressure, plus The number-average molecular weight for entering 63.7g be 18000 PEGDMA-400 and 99.7ml deionized waters prepare it is water-soluble Liquid, the weight concentration of the aqueous solution is 39%；Then heat to 48 DEG C, add 4.78g potassium peroxydisulfates, 4.78g sodium hydrogensulfites and The aqueous solution that 56.4ml deionized waters are prepared, the weight concentration of the aqueous solution is 14.5%, and in 48 DEG C of constant temperature, control ph is 9.6, continue stirring reaction 3.2h, obtain organic amphiprotic copolymerized macromolecule first network gel；Then cooled down, be passed through nitrogen Under gas, organic amphiprotic copolymerized macromolecule first network gel 29.5g inputs 10L can be swelling in closed reactor, in the reactor Equipped with 117.1g itaconic acids, 27.6g glycerine, 276.2g methacrylic acid oxygen ethyl trimellitic anhydrides ester, 21.1g dimethyl The aqueous solution that acrylate diol ester and 3978 deionized waters are prepared, the weight concentration of the aqueous solution is 10%, and first network coagulates The weight of glue（29.5g）:The weight of the aqueous solution（4420g）=1:150, swelling 5.6h；Add 0.88g potassium peroxydisulfates, The aqueous solution that 4.42g pyridoxine hydrochlorides and 21.9ml deionized waters are prepared continues swelling, and the weight concentration of the aqueous solution is 19.5%, swelling 23h；93 DEG C are warming up to after the completion of swelling, control ph is 6.5, in 92 DEG C of isothermal reaction 5.6h, obtain organic Both sexes copolymerized macromolecule interpenetrating networks gel.The gel is water insoluble, can be swelling in water, gel swelling rate（ESR）=7654% （Deionized water）, gel swelling rate（ESR）=7527%（The NaCl aqueous solution of weight concentration 1%）.

Claims (1)

1. a kind of preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel, it is characterized in that can in closed reactor plus Enter component A and deionized water stirring prepares the aqueous solution, it is 28%~62% to control the weight concentration of component A, after the completion of prepared by solution, Relative degree of vacuum is evacuated to for -0.02MPa~-0.08MPa, after being passed through nitrogen recovery reactor to normal pressure, is added under agitation Enter the aqueous solution prepared by B component and deionized water, the weight concentration of B component is 20%~40%, the aqueous solution charging knot of B component Shu Hou, is warming up to 35 DEG C~50 DEG C, and the aqueous solution prepared by component C and deionized water is added under agitation, and the weight of component C is dense It is 5%~15% to spend, and control ph is 4~10, in 35 DEG C~50 DEG C constant temperature, continues stirring reaction 2h~3.5h, obtains organic two Property copolymerized macromolecule first network gel, then cooled down, in the case where nitrogen is passed through, by the first network gel input be equipped with D The aqueous solution that component and deionized water are prepared can be swelling in closed reactor, the weight concentration of D components is 1.8%~11%, is pressed Weight meter, first network gel:Weight ratio=1 of D component deionized water solutions:（95~155）, swelling time is 2h~6h, then The aqueous solution prepared by component E and deionized water is added to continue swelling, the weight concentration of component E is 10%~20%, swelling time Be 16 h~24 h, it is swelling after the completion of, be warming up to 75 DEG C~95 DEG C, control ph is 3~7, in 75 DEG C~95 DEG C constant temperature, reaction 4h~6h, obtains organic amphiprotic copolymerized macromolecule interpenetrating networks gel；The component A is by methylacryoyloxyethyl trimethyl chlorine Change ammonium, dimethylaminoethyl acrylate, forulic acid composition, by the gauge of material, MethacryloyloxyethylTrimethyl Trimethyl Ammonium Chloride: Dimethylaminoethyl acrylate:The ratio between amount of material of forulic acid=（0.5~1.2）:（0.3~1.6）:（0.4~1.1）, B groups It is PEGDMA-400 to divide, and number-average molecular weight is 2000~20000, and its gross weight that feeds intake is component A gross weight 2.5%~11%, component C is made up of potassium peroxydisulfate-sodium hydrogensulfite, its gross weight that feeds intake be component A gross weight 0.3%~ 1.8%, by weight, potassium peroxydisulfate:Weight ratio=1 of sodium hydrogensulfite:（0.2~1.1）, D components are by itaconic acid, the third three Alcohol, methacrylic acid oxygen ethyl trimellitic anhydride ester and dimethacrylate cyclohexanediol ester composition, by the gauge of material, clothing health Acid:Glycerine:The ratio between amount of material of methacrylic acid oxygen ethyl trimellitic anhydride ester=（0.2~1.0）:（0.08~0.32）: （0.4~1.1）, by weight, dimethacrylate cyclohexanediol ester charged material weight is itaconic acid, glycerine, methacrylic acid Three kinds the 1.8%~5.5% of total monomer weight of oxygen ethyl trimellitic anhydride ester, component E is by potassium peroxydisulfate, pyridoxine hydrochloride group Into potassium peroxydisulfate charged material weight is the 0.1%~1.2% of D component weights, and pyridoxine hydrochloride charged material weight is D component gross weights The 0.8%~5.6% of amount.
CN201611127248.XA 2016-12-09 2016-12-09 The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel Pending CN106750406A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201611127248.XA CN106750406A (en) 2016-12-09 2016-12-09 The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201611127248.XA CN106750406A (en) 2016-12-09 2016-12-09 The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel

Publications (1)

Publication Number Publication Date
CN106750406A true CN106750406A (en) 2017-05-31

Family

ID=58881975

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201611127248.XA Pending CN106750406A (en) 2016-12-09 2016-12-09 The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel

Country Status (1)

Country Link
CN (1) CN106750406A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105289316A (en) * 2015-09-28 2016-02-03 浙江大学 Preparation method of composite separating film filled by interpenetrating polymer network hydrogel

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105289316A (en) * 2015-09-28 2016-02-03 浙江大学 Preparation method of composite separating film filled by interpenetrating polymer network hydrogel

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
薛冬桦等: ""P(AA-DAC)两性聚电解质水凝胶的合成及性质"", 《高等学校化学学报》 *
魏佳: ""具有半互穿网络结构的两性吸水树脂的合成及性能研究"", 《中国优秀硕博士学位论文全文数据库（硕士） 工程科技I辑》 *

Similar Documents

Publication Publication Date Title
CN106750009A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106750406A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106750013A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106750017A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106750403A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106750415A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106750014A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106750003A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106750030A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106750026A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106750022A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106750008A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106750018A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106750023A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106750010A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106750407A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106749995A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106749999A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106700101A (en) Preparation method of organic amphoteric copolymerized macromolecular interpenetrating network gel
CN106750025A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106749979A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106699992A (en) Preparation method of organic amphoteric copolymerization macromolecular interpenetrating network gel
CN106749980A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106749998A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel
CN106749974A (en) The preparation method of organic amphiprotic copolymerized macromolecule interpenetrating networks gel

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20170531

WD01 Invention patent application deemed withdrawn after publication