CN106730360A - A kind of internal deep therapy instrument - Google Patents
A kind of internal deep therapy instrument Download PDFInfo
- Publication number
- CN106730360A CN106730360A CN201611270074.2A CN201611270074A CN106730360A CN 106730360 A CN106730360 A CN 106730360A CN 201611270074 A CN201611270074 A CN 201611270074A CN 106730360 A CN106730360 A CN 106730360A
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- China
- Prior art keywords
- flexible
- therapy instrument
- energy source
- internal deep
- liquid metal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/004—Magnetotherapy specially adapted for a specific therapy
- A61N2/006—Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
Abstract
The present invention provides a kind of internal deep therapy instrument, it includes the energy source and control device in implantable and for producing the flexible body and the flexible body in magnetic field to connect, control device is connected with energy source, and flexible body includes liquid metal and packaging body, and liquid metal is sealed in packaging body.The invention provides a kind of simple structure, the internal deep therapy instrument that comfort level is high and therapeutic effect is good, to solve the defect that therapeutic effect is poor, comfort level is not high during existing mental illness is treated.
Description
Technical field
The present invention relates to health care technique with the apparatus field, more particularly, to a kind of internal deep therapy instrument.
Background technology
With society's existence with the increasing of competitive pressure, many people because work, pressure of study etc., cause many nerves
With spiritual disease, such as depression, stress, anxiety disorder and sleep-disorder.
Counted according to the World Health Organization, depression has turned into the fourth-largest illness in the world, has been likely to become to the year two thousand twenty and be only second to
Cardiopathic second largest disease.Conservative estimation, the whole world has 3.5 hundred million patients with depression.Depression is in global morbidity
Rate is about 11%, has 15% suicide can be selected to carry out end lives in serious patient, and 2/3 patient once had the thought committed suiside,
Every year because the Population size estimation of depression committed suicide is up to 1,000,000.The incidence of disease of Chinese depression is calculated 6% or so by this
There are nearly 90,000,000 patients with depression in China.But because the public is not enough to the understanding of depression, the Chinese Spirit medical unit 5 in addition
Strength it is not enough, only 10% patients with depression obtains medical treatment, and remaining 90% about 80,000,000 people is at that " self is supported
It is imperial " state in, China is annual to have 250,000 people to die from suicides, and 2,000,000 people attempt to commit suicide.
And it is current, for mental illness, the treatment of such as depression be substantially based on medicine and psychotherapy, and be
Carried out under the background of medical treatment.Although relatively preferable by drug therapy anti-mental disorder effect, there is side effect in it
Defect.And although psychotherapy has no side effect, but, its therapeutic effect is extremely limited, therefore finds a kind of essence having no side effect
Refreshing methods for the treatment of diseases turn at present treatment mental illness in the urgent need to.
With the development of science and technology, cranium Neural stem cell (TMS) has been widely used among the treatment of mental illness, and is produced
The good mental illness therapeutic effect of life.Wherein, cranium Neural stem cell is a kind of cortical stimulation method, and magnetic signal can be with undamped ground thoroughly
Cross skull and stimulate to cerebral nerve, the stimulation of brains is not limited in practical application, peripheral nerve muscle can equally enter
Assassinate and swash, therefore it is " Neural stem cell " all to cry it now.Neural stem cell is a kind of physical stimulation form, and it is flowed into using changing currents with time
Cerebral magnetic stimulation coil, produces high intensity time-varying pulsed magnetic field, time-varying pulsed magnetic field induction field to be produced in tissue and is inducted
Electric current, induced-current makes some excitable tissues produce a kind of excited stimulating method, with painless, not damaged, it is easy to operate,
Safe and reliable the advantages of, had a wide range of applications in terms of clinical medicine.
Although this transcranial magnetic stimulation has more significant effect on treatment mental illness, there is one
Individual problem, is exactly energy dropoff with the intensification for the treatment of sites depth, causes cerebral deep tissue to be controlled well
Treat.
In order to solve above-mentioned technical problem, one kind is supplied in Chinese patent CN201320100705.1 by shell
The internal magnet therapeutic apparatus of magnetic line of force generator and connecting line composition in the inner is filled, although magnet therapeutic apparatus can be installed in body by the device
Power, magnetic therapy is carried out to patient part using the magnetic line of force launched, but, because the shell is in hard shape, cause it in vivo
When using, Consumer's Experience sense is poor, particularly in the treatment of mental illness, due to its form, causes it to realize inside it
Implantation.
The content of the invention
The present invention provides a kind of simple structure, the internal deep therapy instrument that comfort level is high and therapeutic effect is good, existing to solve
The defect that therapeutic effect is poor in spiritedness disease treatment, comfort level is not high.
According to an aspect of the present invention, there is provided a kind of internal deep therapy instrument, it includes in an implantable and is used for
The energy source and control device of flexible body and the flexible body connection in magnetic field, the control device is produced to connect with the energy source
Connect, the flexible body includes liquid metal and flexible encapsulation, the flexible encapsulation inner surface is provided with spiral passage,
The liquid metal is encapsulated in the passage, and is provided with connector in the passage, and the inner surface of the flexible encapsulation also sets
There is the cell body connected with the end points of the passage, the first flexible wire is provided with the cell body, and be connected with the connector position
The second flexible wires wire being connected with the energy source, the flexible body passes through first flexible wire and the second flexible wire
It is electrical connected with the control device.
On the basis of such scheme preferably, the liquid metal is the alloy of gallium indium tin.
On the basis of such scheme preferably, the flexible body is cylindrical or paster shape is implanting.
On the basis of such scheme preferably, the liquid metals is GaIn24.5, the GaIn24.5It is the conjunction of gallium and indium
The mass ratio of gold, its described gallium and indium is 75.5:24.5.
On the basis of such scheme preferably, the first described flexible wire includes flexible cover and liquid metal, described
Liquid metal is encapsulated in the flexible cover.
On the basis of such scheme preferably, the flexible encapsulation and flexible cover are PDMS.
On the basis of such scheme preferably, the energy source is AC power, and the voltage that the AC power is produced is
0.1V-36V。
On the basis of such scheme preferably, one is additionally provided between the energy source and control device and is used to adjust the energy
Source output current size changes the processing module of magnetic field intensity.
On the basis of such scheme preferably, described control device and the processing module pass through bluetooth, infrared or wireless
Electricity is connected by communication.
The application proposes a kind of internal deep therapy instrument, using the electric conductivity of liquid metal, by flexible package body
The passage of setting, flexible body is formed so that the helical form disk for realizing liquid metal is folded, so that liquid metal can be flowed through by control
Size of current and frequency, produce the effect in magnetic field in flexible body, reach to human body deep tissue such as head, back, in body cavity
The effect of intestinal tract, nerve, muscle, bone etc. magnetic therapy, to realize the purpose for the treatment of nerve and psychosis, improves
Sleep quality, pain of alleviation alleviates muscular tone, accelerates local blood circulation, accelerates treatment and the auxiliary treatments such as intestines peristalsis
Purpose.
Because the present invention has good mobility and flexible encapsulation, the first flexible wire, second using liquid metal
The high flexibility of flexible wire, improves the comfort level that therapeutic equipment of the invention is implanted into human body, to realize what therapeutic equipment implanted
Purpose, to increase its therapeutic effect.
Brief description of the drawings
Fig. 1 is a kind of line schematic diagram of internal deep therapy instrument of the invention
Fig. 2 is the schematic diagram in flexible body implantation cerebral cortex of the invention;
Fig. 3 is that flexible body of the invention is implanted into subcutaneous backbone schematic diagram in the vicinity;
Fig. 4 is the schematic diagram around flexible body implantation abdominal cavity intestinal tissue of the invention.
Specific embodiment
With reference to the accompanying drawings and examples, specific embodiment of the invention is described in further detail.Hereinafter implement
Example is not limited to the scope of the present invention for illustrating the present invention.
Refer to shown in Fig. 1, a kind of internal deep therapy instrument of the invention, including in an implantable and for producing magnetic
The energy source 4 and control device of flexible body and the flexible body connection of field, control device are connected with energy source 4, and flexible body includes
One liquid metal 1 and a packaging body 2, liquid metal 1 are sealed in packaging body 2, and flexible body passes through wire 3 and the electrical phase of energy source
Even.
Wherein, flexible encapsulation inner surface of the invention is provided with spiral passage, and liquid metal is encapsulated in the passage
It is interior, and connector is provided with the passage, and the inner surface of flexible encapsulation is additionally provided with the cell body connected with the end points of passage, cell body
The first flexible wire is inside provided with, and the second flexible wires wire being connected with energy source is connected with the connector position, flexible body leads to
Cross the first flexible wire and the second flexible wire is electrical connected with control device.
The present invention has good mobility using liquid metal, can need to mould different moulding according to different, meets
The need for implanting, meanwhile, using flexible encapsulation of the invention, the first flexible wire, the second flexible wire high flexibility,
To improve the comfort level that the present invention implants, so as to improve therapeutic effect of the invention.
When using, the position according to specific treatment changes the shape of flexible body, as flexible body is designed into winding tissue
In the paster shape of cylindrical form or spiral implanting.After implanting, only reserve two wires 3 be connected in vitro, with
Energy source 4 is electrical connected, with by energy source 4 for flexible body provides operating current, to produce magnetic field.By produced by flexible body
The purpose of pathological tissues is directly treated to reach in magnetic field.Preferably, the wire 3 is liquid metal wire.
Such as it is implanted into cerebral cortex, the release strength of neurotransmitter, intracerebral with the neuron of excited deep brain area, can be adjusted
Concentration of neuromodulator etc. is acted on, and reaches the effect for the treatment of the nervous system disease, such as alleviates depression, is improved the health care of sleep, such as Fig. 2 institutes
Show.If being implanted in peripheral nerve, the position of musculature or neuromuscular contact produces a certain amount of magnetic field at the position,
DOMS, and chronic pain head and postoperative pain can be alleviated, swelling is even eliminated, tissue cell activity and enhancing people is improved
Effect of body immunity, as shown in Figure 3.If being implanted in around enteron aisle, what may be connected with enteron aisle by stimulation is neural
Activity, produces the effect for promoting intestines peristalsis, as shown in Figure 4.
A kind of internal deep therapy instrument of the invention, using liquid metal 1 as magnetic field generation body, using liquid metal
1 liquid fluidity can and good thermal conductivity, flexible body can be designed to different shape, different size of magnetic field generating body,
The need for meet implantation human body.Meanwhile, the high fluidity energy possessed using liquid metal 1, to improve relaxing for implantation human body
Appropriateness.
The present invention provides a kind of comfort level internal deep therapy instrument high, compared with traditional external flexible body treatment,
Because it is implanted in inside of human body pathological tissues portion, can effectively overcome traditional external flexible body treat magnetic field it is weak caused by
The defect of therapeutic effect difference, is greatly improved its therapeutic effect.
Used as the first preferred embodiment of the invention, energy source of the invention 4 is AC power, and the AC power
Operating voltage be 0.1V-36V, i.e., ensure its therapeutic effect while, it is ensured that the security of human body therapy.
Used as second preferred embodiment of the invention, liquid metal of the invention 1 is that liquid metal is gallium indium tin
Alloy or gallium-indium alloy, it is preferred that liquid metals of the invention is GaIn24.5, and GaIn24.5It is gallium and the alloy of indium, described in it
The mass ratio of gallium and indium is 75.5:24.5
Used as second preferred embodiment of the invention, packaging body of the invention 2 is with biocompatibility well and not
The PDMS reacted with liquid metal 1.By packaging body 2 seal liquid metal 1, prevent liquid metal 1 directly with in-vivo tissue phase
Contact, produces adverse reaction, and plays the form of fixed liquid metal 1, to meet different therapentic parts the need for.
As the third preferred embodiment of the invention, in order to realize the volume regulation to internal magnetic field size.The present invention
One is additionally provided between energy source 4 and control device to be used to adjust the output current size of energy source 4 change magnetic field intensity
Processing module 6.The processing module 6 is used for the control signal of receiving control device, and the control signal is converted into for controlling energy
The electrical control signals in amount source 4, by the signal frequency and intensity that control energy source 4 to send, are produced with reaching change flexible body
The purpose of the intensity size of magnetisation.
For the ease of connecting up and using, control device of the invention and the processing module 6 preferably by bluetooth, it is infrared or
Radio communication is connected.
In order to further describe technical scheme, use process of the invention is will be detailed below:
1. clinician does conventional pre-operative preparation, sterilization of instruments etc..
2. the form of the magnetic therapy material in implantation has been planned, it is such as SMD or cylindric.Material is implanted into
Patient's privileged site, and continue to monitor the body temperature and various physical signs of patient.
3. two liquid metal wires are reserved and be connected in vitro and with external power source and signal processing module.
4. the electromagnetic field that deep tissue produces appropriate intensity may be implemented in by control module.
5., if patient produces any discomfort to react, please stop using immediately.
The application proposes a kind of internal deep therapy instrument, and the size of current and frequency of liquid metal 1 are flowed through by control, can
Realize producing the effect of space magnetic field, reach to human body deep tissue such as head, back, intestinal tract in body cavity, nerve, flesh
The effect of meat, bone etc. magnetic therapy, reaches treatment nerve and psychosis, improves the health care of sleep quality, and pain of alleviation alleviates flesh
Meat is nervous, accelerates local blood circulation, accelerates the purpose of the treatments such as intestines peristalsis and auxiliary treatment.
Finally, the present processes are only preferably embodiment, are not intended to limit the scope of the present invention.It is all
Within the spirit and principles in the present invention, any modification, equivalent substitution and improvements made etc. should be included in protection of the invention
Within the scope of.
Claims (9)
1. a kind of internal deep therapy instrument, it is characterised in that it include in implantable and for produce magnetic field flexible body and
The energy source and control device of flexible body connection, the control device are connected with the energy source, and the flexible body includes liquid
State metal and flexible encapsulation, the flexible encapsulation inner surface are provided with spiral passage, and the liquid metal is encapsulated in
In the passage, and connector is provided with the passage, and the inner surface of the flexible encapsulation is additionally provided with end points with the passage
The cell body of connection, is provided with the first flexible wire, and be connected with what is be connected with the energy source in the connector position in the cell body
Second flexible wires wire, the flexible body is electrical with the control device by first flexible wire and the second flexible wire
It is connected.
2. a kind of internal deep therapy instrument as claimed in claim 1, it is characterised in that the liquid metal is the conjunction of gallium indium tin
Gold.
3. a kind of internal deep therapy instrument as claimed in claim 2, it is characterised in that the flexible body is cylindrical or paster
Shape is implanting.
4. a kind of internal deep therapy instrument as claimed in claim 1, it is characterised in that the liquid metals is Ga75.5In24.5,
The GaIn24.5It is gallium and the alloy of indium.
5. a kind of internal deep therapy instrument as claimed in claim 1, it is characterised in that the first described flexible wire includes soft
Property strip of paper used for sealing and liquid metal, the liquid metal are encapsulated in the flexible cover.
6. a kind of internal deep therapy instrument as claimed in claim 5, it is characterised in that the flexible encapsulation and flexible cover
It is PDMS.
7. a kind of internal deep therapy instrument as claimed in claim 1, it is characterised in that the energy source is AC power, institute
The voltage for stating AC power generation is 0.1V-36V.
8. a kind of internal deep therapy instrument as claimed in claim 1, it is characterised in that between the energy source and control device
One is additionally provided with to be used to adjust processing module of the energy source output current size to change magnetic field intensity.
9. a kind of internal deep therapy instrument as claimed in claim 8, it is characterised in that described control device and the treatment mould
Block is connected by bluetooth, infrared or radio communication.
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CN201611270074.2A CN106730360B (en) | 2016-12-30 | 2016-12-30 | A kind of internal deep therapy instrument |
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CN201611270074.2A CN106730360B (en) | 2016-12-30 | 2016-12-30 | A kind of internal deep therapy instrument |
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CN106730360B CN106730360B (en) | 2019-03-01 |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108057173A (en) * | 2017-12-08 | 2018-05-22 | 丰润(泉州)健康科技有限公司 | A kind of physical therapy device and its processing technology |
CN109330642A (en) * | 2018-08-03 | 2019-02-15 | 云南靖创液态金属热控技术研发有限公司 | A kind of endoscope-assistant surgery auxiliary stretching device |
Citations (3)
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US20150080637A1 (en) * | 2013-09-16 | 2015-03-19 | The General Hospital Corporation | Microscopic magnetic coils for neural stimulation |
CN105658272A (en) * | 2013-09-06 | 2016-06-08 | Med-El电气医疗器械有限公司 | Cochlear implant electrode with liquid metal alloy |
CN105944228A (en) * | 2016-04-25 | 2016-09-21 | 清华大学 | Implanted flexible neural electrode based on liquid metal and production method |
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2016
- 2016-12-30 CN CN201611270074.2A patent/CN106730360B/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105658272A (en) * | 2013-09-06 | 2016-06-08 | Med-El电气医疗器械有限公司 | Cochlear implant electrode with liquid metal alloy |
US20150080637A1 (en) * | 2013-09-16 | 2015-03-19 | The General Hospital Corporation | Microscopic magnetic coils for neural stimulation |
CN105944228A (en) * | 2016-04-25 | 2016-09-21 | 清华大学 | Implanted flexible neural electrode based on liquid metal and production method |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108057173A (en) * | 2017-12-08 | 2018-05-22 | 丰润(泉州)健康科技有限公司 | A kind of physical therapy device and its processing technology |
CN109330642A (en) * | 2018-08-03 | 2019-02-15 | 云南靖创液态金属热控技术研发有限公司 | A kind of endoscope-assistant surgery auxiliary stretching device |
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