CN106729963A - A kind of silicone gel dressing and its production technology - Google Patents
A kind of silicone gel dressing and its production technology Download PDFInfo
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- CN106729963A CN106729963A CN201611194768.2A CN201611194768A CN106729963A CN 106729963 A CN106729963 A CN 106729963A CN 201611194768 A CN201611194768 A CN 201611194768A CN 106729963 A CN106729963 A CN 106729963A
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- silicone gel
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/008—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0019—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0066—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0076—Sprayable compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/216—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
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- General Health & Medical Sciences (AREA)
- Public Health (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a kind of silicone gel dressing and its production technology, its formula includes that percentage by weight is respectively 40 80% silicone oil Q7 9120, the dimethyl silicone polymer Q7 9180 of 0.1 20% organic siliconresin silicon oil mixture T1 7021,19 40%, 0.1 3% tea tree ethereal oil and 0.2 1% bisabolol.The present invention makes dressing for medical organic silicon liquid film, does not result in wound adhesion, not allergy, breathes freely, waterproof, effectively suppresses the growth of scar, or even desalinate or eliminate scar.
Description
Technical field
The present invention relates to dressing and its production technology field, more particularly to a kind of silicone gel dressing and its production technology.
Background technology
As the continuous improvement of living standard, people are more and more for the concern that skin wound is nursed, either collide with
Wound, burn and scald, animal are scratched or postoperative wound, are all merely not only that requirement healing is so simple, and more attention is
The aesthetics after comfort level and wound healing during treatment wound.Current main flow surface of a wound nursing dressing is Gauze, non-woven fabrics
Dressing patch, bearing hydrocolloid dressing etc..
Shortcoming/the deficiency of prior art:1st, Gauze easily sticks in wound, very painful during replacing, easily causes secondary
Scar is left after injury, and incrustation, it is difficult to eliminate, is influenceed attractive in appearance;2nd, adhesive-bonded fabric dressing is thicker, poor air permeability, and tape coating
It is pressure sensitive adhesive, easily causes allergic;3rd, bearing hydrocolloid dressing poor air permeability, biocompatibility is also bad, especially cytotoxicity
And sensitization;4th, existing dressing is all to cause local skin anoxic on skin to be sticked on, or some stimulate, sensitization it is existing
As more or less there is uncomfortable sensation;5th, the water resistance of existing dressing is very poor, it is impossible to contact water, is brought very to daily life
Many inconvenience;6th, existing dressing generally can not effectively suppress the generation of scar, can not more desalinate the scar for having generated;7th, it is existing
It can only be hospital or skilled nursing facilities to have dressing Sales Channel, and this product can be used independently to specifications, and carrying side
Just.
The content of the invention
To solve problem present in above-mentioned background technology, it is an object of the invention to provide a kind of silicone gel dressing and
Its production technology, dressing as medical organic silicon liquid film is made to reach, and does not result in wound adhesion, not allergy, is breathed freely, waterproof,
Effectively suppress the growth of scar, or even desalinate or eliminate the purpose of scar.
To reach above-mentioned purpose, technical scheme is as follows:
A kind of silicone gel dressing, its formula includes that percentage by weight is respectively silicone oil Q7-9120,0.1- of 40-80%
The tea of dimethyl silicone polymer Q7-9180,0.1-3% of 20% organic siliconresin silicon oil mixture T1-7021,19-40%
The bisabolol of tree essential oil and 0.2-1%.
Preferably, the viscosity of the silicone oil Q7-9120 is 100cst.
Preferably, the viscosity of the organic siliconresin silicon oil mixture T1-7021 is 12500cst.
Preferably, the viscosity of the dimethyl silicone polymer Q7-9180 is 0.65cst.
Preferably, the EGF of 0.1-1mg/KG is also included in the formula.
A kind of production technology of silicone gel dressing, comprises the following steps:
1) by all batching weighings;
2) elder generation is to addition silicone oil Q7-9120 and organic siliconresin silicon oil mixture T1-7021 in stirred tank and opens stirring;
3) again to silicone oil Q7-9120 is added in stirred tank, continue to stir, control the negative pressure of stirred tank to negative 0.06Mpa;
4) when stirring 15 minutes to substantially uniformity transparence, to tea tree ethereal oil and bisabolol is added in stirred tank, continue
Stirring 5 minutes;
5) stirred 5 minutes to EGF is added in stirred tank again, obtain dressing;
6) above-mentioned dressing is detected and is adjusted physical and chemical index, complied with standard;
7) filling, inspection, packaging, product inspection is finally put in storage.
Preferably, the step 2) in whipping temp control in 18-25 degree, mixing time is 10 minutes.
Preferably, the step 3) in mixing time be 10 minutes.
Preferably, the step 7) in disqualified upon inspection be scrap, product inspection is unqualified to be needed to repack, into
Product are put in storage again after the assay was approved.
The silicone gel dressing provided by above-mentioned technical proposal, the present invention, come real by the way of smearing or spraying
Existing dressing covers the purpose of skin, and the amount of being intended for single use is small, can control the thickness of liquid film, and Packaging Bottle can be with some
It is secondary, it is to avoid with one piece of traditional dressing must to throw away packing inside bag and external packing box, save resource, the energy also protection ring simultaneously
Border, in this product production technology, the generation without waste water, waste gas and product leftover pieces etc., energy-conserving and environment-protective.
Brief description of the drawings
In order to illustrate more clearly about the embodiment of the present invention or technical scheme of the prior art, below will be to embodiment or existing
The accompanying drawing to be used needed for having technology description is briefly described.
Fig. 1 is a kind of flow chart of the production technology of the silicone gel dressing disclosed in the embodiment of the present invention.
Specific embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Site preparation is described.
Embodiment one:
A kind of silicone gel dressing that the present invention is provided, its formula includes that percentage by weight is respectively that viscosity is 100cst
58.9% silicone oil Q7-9120, the organic siliconresin silicon oil mixture T1-7021 of 0.1% that viscosity is 12500cst, viscosity are
The dimethyl silicone polymer Q7-9180 of the 40% of 0.65cst, 3% tea tree ethereal oil and 1% bisabolol, it is aborning
Also need to add the EGF of 0.1mg/KG.
Embodiment two:
A kind of silicone gel dressing that the present invention is provided, its formula includes that percentage by weight is respectively that viscosity is 100cst
80% silicone oil Q7-9120, the organic siliconresin silicon oil mixture T1-7021 of 0.5% that viscosity is 12500cst, viscosity are
The dimethyl silicone polymer Q7-9180 of the 19% of 0.65cst, 0.3% tea tree ethereal oil and 0.2% bisabolol, it is in life
Also need to add the EGF of 0.2mg/KG in product.
Embodiment three:
A kind of silicone gel dressing that the present invention is provided, its formula includes that percentage by weight is respectively that viscosity is 100cst
40% silicone oil Q7-9120, the organic siliconresin silicon oil mixture T1-7021 of 20% that viscosity is 12500cst, viscosity are
The dimethyl silicone polymer Q7-9180 of the 36% of 0.65cst, 3% tea tree ethereal oil and 1% bisabolol, it is aborning
Also need to add the EGF of 0.5mg/KG.
Example IV:
A kind of silicone gel dressing that the present invention is provided, its formula includes that percentage by weight is respectively that viscosity is 100cst
Organic siliconresin silicon oil mixture T1-7021, the viscosity of 50.1% silicone oil Q7-9120,18.5% that viscosity is 12500cst
Dimethyl silicone polymer Q7-9180,2.6% tea tree ethereal oil and 0.8% bisabolol for the 28% of 0.65cst, its
Also need to add the EGF of 1mg/KG in production.
Embodiment five:
A kind of silicone gel dressing that the present invention is provided, its formula includes that percentage by weight is respectively that viscosity is 100cst
45% silicone oil Q7-9120, the organic siliconresin silicon oil mixture T1-7021 of 16% that viscosity is 12500cst, viscosity are
The dimethyl silicone polymer Q7-9180 of the 36% of 0.65cst, 2.4% tea tree ethereal oil and 0.6% bisabolol, it is in life
Also need to add the EGF of 0.8mg/KG in product.
Silicone gel after smearing or spraying forms one layer of ultra-thin liquid film in skin surface, completely cuts off extraneous bacterium,
To the environment that the moistening of wound one is ventilative, silicone molecules film has water-resisting ability, had a bath after this dressing of smearing or spray or
Person swims without influence, while using the exclusive characteristic that can suppress scar of silicone molecules, preventing the generation of scar;For
The scar for having been formed, this dressing can still play a part of to desalinate scar.
The production technology of a kind of silicone gel dressing that the present invention is provided, as shown in figure 1, comprising the following steps:
1) by all batching weighings;
2) elder generation is to addition silicone oil Q7-9120 and organic siliconresin silicon oil mixture T1-7021 in stirred tank and opens stirring,
In 18-25 degree, mixing time is 10 minutes for whipping temp control;
3) again to silicone oil Q7-9120 is added in stirred tank, continue to stir, the time is 10 minutes, controls the negative pressure of stirred tank
To negative 0.06Mpa;
4) when stirring 15 minutes to substantially uniformity transparence, to tea tree ethereal oil and bisabolol is added in stirred tank, continue
Stirring 5 minutes;
5) stirred 5 minutes to EGF is added in stirred tank again, obtain dressing;
6) above-mentioned dressing is detected and is adjusted physical and chemical index, complied with standard;
7) filling, inspection, packaging, product inspection is finally put in storage, and disqualified upon inspection is scrap, and product inspection does not conform to
Lattice need to repack, and are put in storage again after product inspection is qualified.
A kind of silicone gel dressing disclosed by the invention, realizes that dressing covers skin by the way of smearing or spraying
Purpose, the amount of being intended for single use is small, can control the thickness of liquid film, and a Packaging Bottle can be with several times, it is to avoid use one
Block traditional dressing must throw away packing inside bag and external packing box, save resource, the energy also environmental protection, this product production simultaneously
In technique, the generation without waste water, waste gas and product leftover pieces etc., energy-conserving and environment-protective.
The foregoing description of the disclosed embodiments, enables professional and technical personnel in the field to realize or uses the present invention.
Various modifications to these embodiments will be apparent for those skilled in the art, as defined herein
General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, the present invention
The embodiments shown herein is not intended to be limited to, and is to fit to and principles disclosed herein and features of novelty phase one
The scope most wide for causing.
Claims (9)
1. a kind of silicone gel dressing, it is characterised in that its formula includes that percentage by weight is respectively the silicone oil Q7- of 40-80%
9120th, the dimethyl silicone polymer Q7-9180 of organic siliconresin silicon oil mixture T1-7021,19-40% of 0.1-20%,
The tea tree ethereal oil of 0.1-3% and the bisabolol of 0.2-1%.
2. a kind of silicone gel dressing according to claim 1, it is characterised in that the viscosity of the silicone oil Q7-9120 is
100cst。
3. a kind of silicone gel dressing according to claim 1, it is characterised in that the organic siliconresin silicon oil mixture
The viscosity of T1-7021 is 12500cst.
4. a kind of silicone gel dressing according to claim 1, it is characterised in that the dimethyl silicone polymer Q7-
9180 viscosity is 0.65cst.
5. a kind of silicone gel dressing according to claim 1, it is characterised in that also include 0.1-1mg/ in the formula
The EGF of KG.
6. a kind of production technology of silicone gel dressing, it is characterised in that comprise the following steps:
1) by all batching weighings;
2) elder generation is to addition silicone oil Q7-9120 and organic siliconresin silicon oil mixture T1-7021 in stirred tank and opens stirring;
3) again to silicone oil Q7-9120 is added in stirred tank, continue to stir, control the negative pressure of stirred tank to negative 0.06Mpa;
4) when stirring 15 minutes to substantially uniformity transparence, to tea tree ethereal oil and bisabolol is added in stirred tank, continue to stir 5
Minute;
5) stirred 5 minutes to EGF is added in stirred tank again, obtain dressing;
6) above-mentioned dressing is detected and is adjusted physical and chemical index, complied with standard;
7) filling, inspection, packaging, product inspection is finally put in storage.
7. a kind of production technology of silicone gel dressing according to claim 6, it is characterised in that the step 2) in stir
Temperature control is mixed in 18-25 degree, mixing time is 10 minutes.
8. a kind of production technology of silicone gel dressing according to claim 6, it is characterised in that the step 3) in stir
The time is mixed for 10 minutes.
9. a kind of production technology of silicone gel dressing according to claim 6, it is characterised in that the step 7) in inspection
Unqualified as scrap is tested, product inspection is unqualified to be needed to repack, and is put in storage again after product inspection is qualified.
Priority Applications (1)
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CN201611194768.2A CN106729963A (en) | 2016-12-22 | 2016-12-22 | A kind of silicone gel dressing and its production technology |
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CN201611194768.2A CN106729963A (en) | 2016-12-22 | 2016-12-22 | A kind of silicone gel dressing and its production technology |
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CN201611194768.2A Pending CN106729963A (en) | 2016-12-22 | 2016-12-22 | A kind of silicone gel dressing and its production technology |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110227176A (en) * | 2018-03-05 | 2019-09-13 | 江苏昌吉永生物科技股份有限公司 | Scar eliminating silicone gel dressing and preparation method thereof |
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CN103127543A (en) * | 2013-03-13 | 2013-06-05 | 潘银根 | Silicone dressing, and preparation method and use thereof |
CN103223191A (en) * | 2013-04-28 | 2013-07-31 | 苏州美山子制衣有限公司 | Silicone gel composition for manufacturing breast prosthesis, and preparation method thereof |
CN103517738A (en) * | 2011-03-25 | 2014-01-15 | 于尔戈实验室 | Film-forming composition containing a sun filter, and use thereof for treatment of scars |
US20150086496A1 (en) * | 2013-09-25 | 2015-03-26 | Far Eastern New Century Corporation | Composition of scar gel |
US20160106659A1 (en) * | 2013-12-10 | 2016-04-21 | Englewood Lab, Llc | Polysilicone base for scar treatment |
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2016
- 2016-12-22 CN CN201611194768.2A patent/CN106729963A/en active Pending
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CN1527729A (en) * | 2001-07-24 | 2004-09-08 | \ | Topical pharmaceutical formulation |
CN103517738A (en) * | 2011-03-25 | 2014-01-15 | 于尔戈实验室 | Film-forming composition containing a sun filter, and use thereof for treatment of scars |
CN103127543A (en) * | 2013-03-13 | 2013-06-05 | 潘银根 | Silicone dressing, and preparation method and use thereof |
CN103223191A (en) * | 2013-04-28 | 2013-07-31 | 苏州美山子制衣有限公司 | Silicone gel composition for manufacturing breast prosthesis, and preparation method thereof |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN110227176A (en) * | 2018-03-05 | 2019-09-13 | 江苏昌吉永生物科技股份有限公司 | Scar eliminating silicone gel dressing and preparation method thereof |
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Application publication date: 20170531 |