CN106726124B - Glaucoma drainage tube capable of being quantitatively regulated through non-invasive method - Google Patents
Glaucoma drainage tube capable of being quantitatively regulated through non-invasive method Download PDFInfo
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- CN106726124B CN106726124B CN201710122145.2A CN201710122145A CN106726124B CN 106726124 B CN106726124 B CN 106726124B CN 201710122145 A CN201710122145 A CN 201710122145A CN 106726124 B CN106726124 B CN 106726124B
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- tube
- wide rubber
- drainage
- drainage tube
- inner tube
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/84—Drainage tubes; Aspiration tips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0612—Eyes
Abstract
The glaucoma drainage tube capable of being quantitatively regulated by a non-invasive method comprises a hollow wide rubber tube and a thin drainage tube, wherein the hollow wide rubber tube plays a role of drainage of aqueous humor, an inner tube with equal length is arranged in the hollow wide rubber tube, a plurality of diaphragms are obliquely arranged in the inner tube, a diaphragm support tube is supported between the adjacent diaphragms, a plurality of micropores are formed in the wall of the hollow wide rubber tube to enable the inner tube to be communicated with the outside of the hollow wide rubber tube, the tail end of the thin drainage tube is communicated with the inner tube, the front end of the thin drainage tube is inserted in an anterior chamber, the inner tube cavity at the front end of the diaphragm close to the thin drainage tube is communicated with the thin drainage tube, and aqueous humor is drained from the anterior chamber to nearby eye socket tissues through the micropores of the hollow wide rubber tube; after the operation, the number of the diaphragms close to the thin drainage tube can be increased gradually through laser, so that the flow guiding space communicated between the non-opened diaphragms close to the thin drainage tube and the thin drainage tube is increased gradually, the intraocular pressure of orbital tissues is further reduced through increasing the aqueous humor drainage quantity gradually, and the in-vitro laser noninvasive adjustment of the aqueous humor drainage quantity of glaucoma is realized.
Description
Technical Field
The application relates to the field of medical instruments, in particular to a glaucoma drainage tube which can be quantitatively regulated by a non-invasive method.
Background
At present, an ophthalmic doctor controls the intraocular pressure of a glaucoma patient by adopting a glaucoma drainage tube, and particularly when treating complex glaucoma, a plurality of glaucoma drainage tubes are available at present, the surface area of the glaucoma drainage tube or drainage valve used at present is small, and the glaucoma drainage tube or drainage valve is gradually lost after being wrapped by an mechanized membrane. The pressure control with the simple pressure control valve inside is extremely inaccurate and is easy to fail. The prior drainage tube or drainage valve can not be quantitatively regulated at the later stage according to the needs after the operation, and can be replaced only after failure. In addition, the target intraocular pressure of glaucoma in different stages is different, and the existing simple pressure control valve cannot set the target intraocular pressure before operation or adjust the target intraocular pressure after operation, so that the illness state of part of patients after operation is continuously aggravated.
In order to solve the above problems, the present inventors have filed a patent with application number 201620483179.5, and the application technology is to provide a piston type inner tube in an integral drainage tube, wherein the piston type inner tube can be adjusted in two directions, and in practical application, an mechanized film wrapping the whole drainage device is gradually thickened, the drainage effect is gradually reduced year by year, the intraocular pressure is gradually increased, and in the future, the situation that the intraocular pressure needs to be increased is relatively few, and the drainage effect needs to be further increased generally, and the bidirectional adjustment is not needed. However, when the intraocular pressure is regulated, the prior art needs to cut open eye surface tissues such as conjunctiva, and push or pull out part of the piston, which is easy to cause complications such as bleeding, infection, scar formation and the like, and generates higher operation and related cost.
Disclosure of Invention
In order to solve the technical problems, the glaucoma drainage tube which can be quantitatively regulated by a non-invasive method is provided, the quantitative regulation of drainage quantity of local aqueous humor of glaucoma can be realized by a non-invasive method, the drainage tube does not need to be replaced, eye surface tissues such as conjunctiva and the like do not need to be cut, the purpose of regulating intraocular pressure step by step is achieved almost in a noninvasive manner, the regulation of the local drainage effect is more timely, and the effect of protecting optic nerves is improved.
In order to achieve the above purpose, the technical scheme of the application is as follows:
a glaucoma drainage tube which can be quantitatively regulated by a non-invasive method comprises a hollow wide rubber tube, a thin drainage tube, a plurality of diaphragms and a diaphragm support tube, wherein the hollow wide rubber tube, the thin drainage tube, the plurality of diaphragms and the diaphragm support tube are arranged on the surface of a sclera near the equatorial portion of an eyeball and play a role in drainage of aqueous humor; the inner tube with equal length is arranged in the hollow wide rubber tube along the length direction of the hollow wide rubber tube, the plurality of diaphragms are obliquely and uniformly arranged in the inner tube, the inner tube is divided into a plurality of sections of closed spaces, a plurality of micropores perpendicular to the inner tube are formed in the wall of the hollow wide rubber tube to enable the inner tube to be communicated with the outside of the hollow wide rubber tube, the tail end of the thin drainage tube is communicated with the inner tube of the hollow wide rubber tube, the front end of the thin drainage tube is inserted in the anterior chamber, the inner tube cavity at the front end of the diaphragm close to the thin drainage tube is communicated with the thin drainage tube, and aqueous humor drained from the anterior chamber is drained to the adjacent orbit tissue through the micropores of the wall of the hollow wide rubber tube through the inner tube at the position; according to the rising degree of the intraocular pressure after the operation, one diaphragm close to the thin drainage tube is sequentially opened or a plurality of diaphragms are sequentially opened through laser, so that a laser hole is formed in the diaphragm, the diversion space communicated between the unopened diaphragm close to the thin drainage tube and the thin drainage tube is gradually increased, the drainage quantity of aqueous humor is gradually increased, the intraocular pressure of eye orbit tissues is further reduced, and the noninvasive adjustment of the aqueous humor drainage quantity of glaucoma by external laser is realized.
Preferably, the diaphragm is made of one or more materials with better biocompatibility, such as dark silica gel, hydrogel or polymethyl methacrylate.
Preferably, the plurality of diaphragms are uniformly and obliquely arranged in the inner tube, and the inclination angles of the diaphragms are the same and are all between 10 and 80 degrees.
Preferably, the cross sections of the hollow wide rubber tube and the inner tube are round, elliptic or waist-shaped holes, the cross sections of the diaphragm and the inner tube of the blocked part are consistent, and a plurality of micropores are arranged to communicate the hollow wide rubber tube with the inner tube.
Preferably, the hollow wide rubber tube is made of one or more materials with a semipermeable membrane or a silicon sponge and a water permeable function.
According to the technical scheme, the hollow wide rubber tube and the thin drainage tube which play a role in drainage of aqueous humor are arranged on the surface of the sclera near the equatorial portion of the eyeball, an inner tube with equal length is arranged inside the hollow wide rubber tube along the length direction of the hollow wide rubber tube, a plurality of diaphragms are uniformly and obliquely arranged in the inner tube, a diaphragm support tube is supported between every two adjacent diaphragms and divides the inner tube into a plurality of closed spaces, a plurality of micropores perpendicular to the inner tube are formed in the wall of the hollow wide rubber tube so that the inner tube is communicated with the outside of the hollow wide rubber tube, the tail end of the thin drainage tube is communicated with the inner tube of the hollow wide rubber tube, the front end of the thin drainage tube is inserted in the anterior chamber, the inner tube cavity at the front end of the diaphragm near the thin drainage tube is communicated with the thin drainage tube, and aqueous humor drained from the anterior chamber is drained to the adjacent eye orbit tissues through the micropores of the wall of the hollow wide rubber tube; according to the rising of intraocular pressure, one diaphragm close to the thin drainage tube is opened through laser or a plurality of diaphragms are opened in sequence after an operation, so that a diversion space communicated between the un-opened diaphragm close to the thin drainage tube and the thin drainage tube is gradually increased, the drainage quantity of aqueous humor is gradually increased, the intraocular pressure of orbital tissues is further reduced, and the non-invasive adjustment of the aqueous humor drainage quantity of glaucoma by external laser is realized. Therefore, the purpose of regulating the drainage quantity of the local aqueous humor of the glaucoma by a non-invasive method can be achieved, the drainage tube does not need to be replaced, eye surface tissues such as conjunctiva do not need to be cut, the purpose of regulating the intraocular pressure step by step is achieved almost noninvasively, the local drainage effect is timely regulated, and the effect of protecting the optic nerve is improved. Thereby achieving the purposes of novel design, reasonable structure and good application effect.
Drawings
In order to more clearly illustrate the embodiments of the application or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the application, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic view showing the internal structure of a glaucoma drainage tube quantitatively adjustable by a non-invasive method according to an embodiment of the present application;
FIG. 2 is a schematic view of the laser drilling operation of the A-A direction cut surface in FIG. 1;
fig. 3 is an enlarged view of a portion B in fig. 1.
Corresponding part names are indicated by numerals and letters in the drawings:
1. hollow wide rubber tube 11, inner tube 12, closed space 2, diaphragm 3, thin drainage tube 4, micropore 5, diaphragm support tube 6, anterior chamber 7, laser 71, laser hole
Detailed Description
The following description of the embodiments of the present application will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present application, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.
The present application will be described in further detail with reference to examples and embodiments.
Examples.
As shown in fig. 1, 2 and 3, a glaucoma drainage tube quantitatively adjustable by a non-invasive method, comprising a hollow wide rubber tube 1 provided on the surface of the sclera near the equator of the eyeball to serve as drainage of aqueous humor, a thin drainage tube 3, a plurality of membranes 2 and a membrane support tube 5 supported between adjacent membranes; the inside of the hollow wide rubber tube 1 is provided with an inner tube 11 with equal length along the length direction, the plurality of diaphragms 2 are obliquely and uniformly arranged in the inner tube 11, the inner tube 11 is divided into a plurality of sections of closed spaces 12, a plurality of micropores 4 perpendicular to the inner tube 11 are formed in the tube wall of the hollow wide rubber tube 1 so that the inner tube 11 is communicated with the outside of the hollow wide rubber tube 1, the tail end of the thin drainage tube 3 is communicated with the inner tube 11 of the hollow wide rubber tube, the front end of the thin drainage tube is inserted in the anterior chamber 6, the inner tube cavity at the front end of the diaphragm 2 close to the thin drainage tube 3 is communicated with the thin drainage tube 3, and aqueous humor drained from the anterior chamber 6 is drained to nearby eye socket tissues through the micropores of the tube wall of the hollow wide rubber tube 1 through the inner tube 11; according to the rise of intraocular pressure after the operation, one membrane 2 close to the thin drainage tube 3 is sequentially opened or a plurality of membranes 2 are sequentially opened through laser 7, so that a laser hole 71 is formed in the membrane, the diversion space communicated between the un-opened membrane 2 close to the thin drainage tube 3 and the thin drainage tube 3 is gradually increased, the drainage quantity of aqueous humor is gradually increased, the intraocular pressure of orbital tissues is further reduced, and the noninvasive adjustment of the drainage quantity of aqueous humor of glaucoma by external laser is realized.
The diaphragm 2 is made of one or more materials with better biocompatibility, such as dark silica gel, hydrogel or polymethyl methacrylate, so as to facilitate laser absorption to achieve rapid opening. The plurality of diaphragms 2 are uniformly and obliquely arranged in the inner tube 11, and the inclination angles are the same and are all between 10 and 80 degrees. The cross sections of the hollow wide rubber tube 1 and the inner tube 11 are round, elliptic or waist-shaped hole shapes, and the cross sections of the diaphragm 2 and the inner tube 11 of the blocked part are consistent. The hollow wide rubber tube 1 is made of one or more materials with a semipermeable membrane or a silicon sponge and a water permeable function.
In the embodiment, the glaucoma drainage tube is characterized in that a hollow wide rubber tube 1 and a thin drainage tube 3 which play a role in drainage of aqueous humor are arranged on the surface of a sclera near the equatorial portion of an eyeball, an inner tube 11 with equal length is arranged inside the hollow wide rubber tube 1 along the length direction of the hollow wide rubber tube, a plurality of diaphragms 2 are uniformly and obliquely arranged in the inner tube 11, a diaphragm support tube 5 is supported between adjacent diaphragms 2, the inner tube 11 is divided into a plurality of sections of closed spaces 12, a plurality of micropores 4 perpendicular to the inner tube are formed in the wall of the hollow wide rubber tube 1 so that the inner tube 11 is communicated with the outside of the hollow wide rubber tube 1, the tail end of the thin drainage tube 3 is communicated with the inner tube 11 of the hollow wide rubber tube 1, the front end of the thin drainage tube 3 is inserted into an anterior chamber 6, and aqueous humor drained from the anterior chamber 6 is drained to the adjacent orbital tissue through the micropores 4 of the wall of the hollow wide rubber tube; after the operation, according to the rise of the intraocular pressure, one membrane 2 close to the thin drainage tube 3 is opened by the laser 7 or a plurality of membranes 2 are opened in sequence, so that the diversion space communicated between the unopened membrane 2 close to the thin drainage tube 3 and the thin drainage tube 3 is gradually increased, the drainage quantity of aqueous humor is gradually increased, the intraocular pressure of orbital tissues is further reduced, and the noninvasive adjustment of the drainage quantity of aqueous humor of glaucoma by external laser is realized. Therefore, the purpose of regulating the drainage quantity of the local aqueous humor of the glaucoma by a non-invasive method can be achieved, the drainage tube does not need to be replaced, eye surface tissues such as conjunctiva do not need to be cut, the purpose of regulating the intraocular pressure step by step is achieved almost noninvasively, the local drainage effect is timely regulated, and the effect of protecting the optic nerve is improved. Further achieves the purposes of novel design, reasonable structure and good application effect.
The foregoing is merely a preferred embodiment of the glaucoma drainage tube quantitatively adjustable by non-invasive means of the present application, and it should be noted that modifications and improvements can be made by those skilled in the art without departing from the inventive concept of the present application, which falls within the scope of the present application.
Claims (5)
1. A glaucoma drainage tube quantitatively adjustable by a non-invasive method is characterized by comprising a hollow wide rubber tube, a thin drainage tube, a plurality of diaphragms and diaphragm support tubes, wherein the hollow wide rubber tube, the thin drainage tube, the plurality of diaphragms and the diaphragm support tubes are arranged near the equatorial portion of an eyeball and serve as drainage tubes for aqueous humor; the inner tube with equal length is arranged in the hollow wide rubber tube along the length direction of the hollow wide rubber tube, the plurality of diaphragms are obliquely and uniformly arranged in the inner tube, the inner tube is divided into a plurality of sections of closed spaces, a plurality of micropores perpendicular to the inner tube are formed in the wall of the hollow wide rubber tube to enable the inner tube to be communicated with the outside of the hollow wide rubber tube, the tail end of the thin drainage tube is communicated with the inner tube of the hollow wide rubber tube, the front end of the thin drainage tube is inserted in the anterior chamber, the inner tube cavity at the front end of the diaphragm close to the thin drainage tube is communicated with the thin drainage tube, and aqueous humor drained from the anterior chamber is drained to the adjacent orbit tissue through the micropores of the wall of the hollow wide rubber tube through the inner tube at the position; according to the rising degree of the intraocular pressure after the operation, one diaphragm close to the thin drainage tube is sequentially opened or a plurality of diaphragms are sequentially opened through laser, so that a laser hole is formed in the diaphragm, the diversion space communicated between the unopened diaphragm close to the thin drainage tube and the thin drainage tube is gradually increased, the drainage quantity of aqueous humor is gradually increased, the intraocular pressure of eye orbit tissues is further reduced, and the noninvasive adjustment of the aqueous humor drainage quantity of glaucoma by external laser is realized.
2. The glaucoma drainage tube quantitatively adjustable by a non-invasive method according to claim 1, wherein the membrane is made of one or more materials with better biocompatibility, such as dark silica gel, hydrogel or polymethyl methacrylate.
3. A glaucoma drainage tube according to claim 1 or 2, wherein the plurality of membranes are uniformly inclined in the inner tube at the same inclination angle of between 10 ° and 80 °.
4. A glaucoma drainage tube quantitatively adjustable by a non-invasive method according to claim 3, wherein the cross section of the hollow wide rubber tube and the inner tube is circular, oval or waist-shaped, and the cross section of the membrane and the inner tube of the blocked portion are identical, and a plurality of micro holes are provided to connect the hollow wide rubber tube and the inner tube.
5. The glaucoma drainage tube quantitatively adjustable by a non-invasive method according to claim 4, wherein the hollow wide rubber tube is made of one or more materials having a permeable function of a semipermeable membrane or a silicon sponge.
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CN106726124B true CN106726124B (en) | 2023-08-18 |
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JP6529050B2 (en) * | 2017-10-23 | 2019-06-12 | 株式会社ドックスネット | Implant and implant system |
EP3911285A4 (en) * | 2019-01-18 | 2022-10-19 | Shifamed Holdings, LLC | Adjustable flow glaucoma shunts and methods for making and using same |
US11737920B2 (en) | 2020-02-18 | 2023-08-29 | Shifamed Holdings, Llc | Adjustable flow glaucoma shunts having non-linearly arranged flow control elements, and associated systems and methods |
US11766355B2 (en) | 2020-03-19 | 2023-09-26 | Shifamed Holdings, Llc | Intraocular shunts with low-profile actuation elements and associated systems and methods |
JP2023522332A (en) | 2020-04-16 | 2023-05-30 | シファメド・ホールディングス・エルエルシー | ADJUSTABLE GLAUCOMA TREATMENT DEVICES AND RELATED SYSTEMS AND METHODS |
US11865283B2 (en) | 2021-01-22 | 2024-01-09 | Shifamed Holdings, Llc | Adjustable shunting systems with plate assemblies, and associated systems and methods |
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CN103476371A (en) * | 2011-02-23 | 2013-12-25 | 格里沙贝眼科研究基金会 | Implant for treating glaucoma |
CN203749684U (en) * | 2014-02-20 | 2014-08-06 | 深圳市盐田区人民医院 | Adjustable glaucoma drainage system |
CN105748193A (en) * | 2016-05-25 | 2016-07-13 | 杨勋 | Adjustable glaucoma drainage tube |
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US7909789B2 (en) * | 2006-06-26 | 2011-03-22 | Sight Sciences, Inc. | Intraocular implants and methods and kits therefor |
US10238536B2 (en) * | 2012-10-11 | 2019-03-26 | The Regents Of The University Of Colorado, A Body Corporate | Ocular filtration devices, systems and methods |
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CN103476371A (en) * | 2011-02-23 | 2013-12-25 | 格里沙贝眼科研究基金会 | Implant for treating glaucoma |
CN203749684U (en) * | 2014-02-20 | 2014-08-06 | 深圳市盐田区人民医院 | Adjustable glaucoma drainage system |
CN105748193A (en) * | 2016-05-25 | 2016-07-13 | 杨勋 | Adjustable glaucoma drainage tube |
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