CN106668985A - Real-time monitoring system for transfusion - Google Patents

Real-time monitoring system for transfusion Download PDF

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Publication number
CN106668985A
CN106668985A CN201611198822.0A CN201611198822A CN106668985A CN 106668985 A CN106668985 A CN 106668985A CN 201611198822 A CN201611198822 A CN 201611198822A CN 106668985 A CN106668985 A CN 106668985A
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CN
China
Prior art keywords
drop
transfusion
monitoring system
foot
micro treatment
Prior art date
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Pending
Application number
CN201611198822.0A
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Chinese (zh)
Inventor
王小利
陈广奕
王诗林
陈晓鹏
刘海波
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Shandong University
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Shandong University
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Publication date
Application filed by Shandong University filed Critical Shandong University
Priority to CN201611198822.0A priority Critical patent/CN106668985A/en
Publication of CN106668985A publication Critical patent/CN106668985A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831Monitoring, detecting, signalling or eliminating infusion flow anomalies

Abstract

The invention discloses a real-time monitoring system for transfusion. The system comprises a PC upper computer and a mobile phone and is characterized in that a drop terminal node device is disposed on a murphy's dropper; a PC end monitoring system is inlaid in the PC upper computer; a mobile phone end monitoring system is disposed in the mobile phone; the drop terminal node device is composed of a shell body and a terminal node circuit board inside the shell body; an alarm circuit module, a power supply circuit module, a drop terminal micro-processing module, a detection circuit module and a switch circuit module are disposed on the terminal node circuit board; the alarm circuit module, the detection circuit module and the switch circuit module are connected to the drop terminal micro-processing module; and the drop terminal micro-processing module supplies power via the power supply circuit module. The system has the advantages of low equipment power consumption, quick responses, high signal intensity, low frequency offset, weak interference resistance, high collection accuracy, etc.

Description

Transfusion real-time monitoring system
Technical field
The present invention relates to technical field of medical equipment, specifically a kind of transfusion real-time monitoring system.
Background technology
In general, venous transfusion is one of conventional means among Hospital medical, with current medical resource all the more Anxiety, the several nurses on duty of center transfusion room of a large hospital often will simultaneously manage over hundreds of patients, need to monitor institute There is the transfusion condition of patient such as whether there is blood coagulation, drop is stopped, and transfusion speed is too fast, if situations such as transfusion terminates, particularly When infusion-completed, if medical personnel do not take in time disposal, easily there is air formation air embolism and jeopardize patients ' lives.Together When, hospital ward is often that room is arranged and area big bed in ward is more, and it is not enough that nurse makes an inspection tour dynamics, such as occur nobody accompany and attend to and The patient that can not be taken care of oneself, also occurs above dangerous situation.
Jing is retrieved, and CN2010101217169 discloses a kind of transfusion method for real-time monitoring and infusion real-time monitoring device Patent of invention, it includes the step of infusion bottle or transfusion bag to installing liquid medicine carries out weight detecting, and the step is included to transfusion The weight of bottle or transfusion bag is bound, and judges the volume specification of infusion bottle or transfusion bag, and to the infusion bottle of the volume specification Or the weight of transfusion bag is preset;It also includes alarming step, i.e., when the gross weight of detected infusion bottle or transfusion bag Remove after the weight of default infusion bottle or transfusion bag remaining medicinal liquid nt wt net weight automatic alarm when entering pre-set interval.This The bright volume specification that infusion bottle or transfusion bag just can be automatically defined after transfusion bag is hung up, and by the defeated of the volume specification The weight of liquid bottle or transfusion bag is preset, and the judgement of remaining medicinal liquid nt wt net weight is carried out, so as to complete alarm procedure.Originally simultaneously Invention also provides infusion real-time monitoring device, can implement the transfusion method for real-time monitoring.The substantive deficiency of this method is: One is that in the computer adapter of PC host computers, common program step is:Scanning-loaded down with trivial details with p- connection-communication-disconnection Process, causes equipment response speed slow;Two is that the signal of telecommunication collected due to infrared sensor needs to be filtered through hardware circuit After process, required information can be just obtained, therefore, equipment power dissipation is big, and signal intensity is weak, frequency deviation is big, capacity of resisting disturbance is weak, adopt Collection precision is low.
The content of the invention
It is an object of the invention to solve the deficiencies in the prior art, there is provided a kind of equipment power dissipation is low, fast response time, signal Intensity is high, the transfusion real-time monitoring system that frequency deviation is little, capacity of resisting disturbance is weak, acquisition precision is high.
The technical solution adopted for the present invention to solve the technical problems is:
One kind transfusion real-time monitoring system, including PC host computers and mobile phone, it is characterised in that Murphy type burette is provided with drop end End node device, the PC host computers are embedded with PC ends monitoring system, and mobile phone terminal monitoring system, the liquid are provided with the mobile phone Drop terminal node device is into the terminal node circuit board is provided with report by the terminal node circuit board group in housing and housing Alert circuit module, power supply circuits module, drop terminal micro treatment module, detection circuit module and on-off circuit module, the report Alert circuit module, detection circuit module and on-off circuit module are connected respectively with drop terminal micro treatment module, the drop Terminal micro treatment module Jing power supply circuits module for power supply, by drop terminal micro treatment module be managed collectively warning circuit module, The power supply of detection circuit module and on-off circuit module, to reach effect low in energy consumption;
The drop terminal micro treatment module Jing USB serial communication modules are connected with the PC ends monitoring system of PC host computers, institute State mobile phone terminal Program Monitoring System to fill with the drop terminal node using the NOTIFICATION modes listened to based on protocol stack Drop terminal micro treatment module in putting carries out point-to- point communication,
The monitoring algorithm of the drop terminal micro treatment module includes transfusion speed timekeeping system and alarm timer system, described defeated The algorithm of liquid speed degree timekeeping system is processed using thresholding filtering and forgetting algorithm, and its step is:Infrared tube gathers cyclopentadienyl Fei Shi drops Manage the signal of the diffuse-reflectance and refraction effect dripped with medicinal liquid and be converted to the signal of telecommunication, drop terminal micro treatment module is in the electricity that charges Up and down fluctuation is 0.1-0.3V under the electric power thus supplied of road, that is, it is 2-8% to detect change in voltage, because each drop signal is all present One impact end peak, is directly AD converted signal for the process of this signal is adopted, by the signal of telecommunication numerical value for collecting Amplify, and set two threshold values, when higher limit is broken through, mark position TRUE, mark position FALSE when breaking through lower limit, Flag bit is designated as detecting a drop when converting twice;If detect signal end peak impact, according to drop when Between stab information compare, judge drop frequency, be omitted less than the drop information of intervals;
The algorithm steps of the alarm timer system are:When often detecting drop signal on drop terminal micro treatment module, report to the police Flag bit resets, and timekeeping system two resets;And by setting warning duration, when long-time can't detect drop signal, timing Two timing length of system exceed the warning duration of setting, and warning mark position is hung up, and driven by program warning circuit module sends alarm Information;When drop signal is detected again, by resetting to warning mark position, can sound all clear;
The algorithm steps of the drop terminal micro treatment module are:Drop terminal micro treatment module when drop signal is detected, Timestamp is intercepted, and compares last timestamp, calculate time difference QUOTE between two drop signals , and ask for Meansigma methodss QUOTE of adjacent ten drops interval time , and have following equation to draw transfusion speed:
QUOTE (Formula 3)
And transfusion total amount information is encapsulated in drop terminal micro treatment module with No. ID of transfusion speed and terminal node,
When the monitoring system poll instruction of PC ends is received, the packet in drop terminal micro treatment module is uploaded to the monitoring of PC ends System, patient cases' information that doctor passes through input in the monitoring system of PC ends, using MAC IEEE addresses are directly called out, completes blind Connection, it is possible to while at least 3 drop terminal node devices of effectively connection, and connect reading one by one by the way of poll inquiry The effective information on terminal node is taken, single terminal node device connection reading information to the time for disconnecting is less than The information gathering of 100 terminal nodes, efficient quick can be completed in 5ms, i.e., 1 second;
When inquiring about in mobile phone terminal monitoring system, the mobile phone terminal monitoring system receives what drop terminal micro treatment module was uploaded Each drop timestamp and drop total amount in packet in drop terminal micro treatment module, and calculate transfusion speed, defeated Liquid residual liquid quantity, transfusion remaining time, whether drip and stop and information about power, doctor or nurse or entourage is passed through The mobile phone terminal monitoring system monitor in real time transfusion state, significantly improves the safety of patient.
The specific algorithm step of PC ends of the present invention monitoring system is:
First, the number of drops that the every 1ml of total amount and institute's transfusion that infuses is included is manually entered,
PC ends monitoring system reads the packet of drop terminal micro treatment module, No. ID in the packet that will be read first and number Compare according to the medical record number in storehouse, and the drop total amount information and transfusion speed information in poll read data packet, and supervised by PC ends The transfusion total amount information and droplet size information arranged in control system draws and formula is calculated as below:
QUOTE (Formula 3)
The wherein QUOTE of formula 3 Present infusion surpluses are represented, unit is ml;
QUOTE Plan transfusion total amount is represented, unit is ml;
Num represents the transfusion drop sum obtained from terminal node, and num/ml is the drop that every 1ml of institute's transfusion is included Number;
To calculate present infusion surpluses information, to reach the effect of unified management;
When PC ends monitoring system monitors to infuse total amount residue less than 20ml, then send alarm, prompting nurse carry out pulling out pin or Change section operation;Or, when running voltage is detected less than 3.3V, by drop terminal micro treatment module, PC host computers are sent out Go out the low alarm of electricity, remind staff to be charged to battery in time.
When PC host computers of the present invention are started shooting every time or every 5 minutes, by PC ends monitoring system to outside confession Electric pin is AD converted, be beneficial to reduction MCU computing loads, the actual measuring and calculating of Jing, when battery power for critical point 3.2V when, just Often can hold on more than 120 minutes under working condition.
The specific algorithm step of mobile phone terminal monitoring system of the present invention is:Input transfusion total amount and every in systems first The number of drops that ml is included, when the data uploaded in detecting drop terminal MCU single-chip microcomputer are surrounded by drop signal, program Automatically timestamp is intercepted, and drop total amount is added up, and transfusion speed information is calculated by monitoring system, specific algorithm is such as Under:
QUOTE (Formula 1)
The wherein QUOTE of formula 1 For the volume of transfusion per minute, unit is ml/min,
QUOTE For the difference of the timestamp of Qian Hou two drop,
Num/ml is the number of drops that every 1ml of institute's transfusion is included;
Following information is drawn by the volume of every drop of liquid:
QUOTE (Formula 2)
The wherein QUOTE of formula 2 Present infusion surpluses are represented, unit is ml;
QUOTE Plan transfusion total amount is represented, unit is ml.
Num represents the transfusion drop sum obtained from terminal node;
Num/ml is the number of drops that every 1ml of institute's transfusion is included,
So that patient or family numbers of patients are by the mobile phone real time inspection transfusion condition of oneself.
Computer adapter is provided between PC host computers of the present invention and drop terminal node device, the computer adapter is adopted With MCU the and BLE host protocol stacks of CC2540, due to each CC2540 it is unique with the whole world of one 6 when dispatching from the factory IEEE addresses, and this MAC IEEE address among being entrained in broadcast message, is stored in into PC when terminal node sends broadcast In the packet of the drop terminal micro treatment module of end monitoring system, and as unique sign distribution ID, when drop terminal it is micro- Packet Jing drop terminal MCU single-chip microcomputers in processing module are sent in the concrete connection procedure of PC ends monitoring system, by transferring Protocol stack main frame connectivity function function, directly writes MAC IEEE addresses, and on the IEEE ground for setting terminal node before Location type and IEEE address sizes, complete mandatory connection, i.e., blind connection, so make connection procedure abbreviation for " connection-logical News-disconnect and owning ", eliminate the cumbersome process of troublesome " scanning-pairing-connection-communication-disconnection ", save 95% Time.
Drop terminal micro treatment module of the present invention is by electric capacity C1, electric capacity C2, electric capacity C3, electric capacity C10, electric capacity C11, chip U1 and crystal oscillator Y1, Y2 constitute MCU work systems, and the electric capacity C3 is responsible for the in-line power voltage stabilizing of chip U1, electric capacity C1, C2, crystal oscillator Y1 constitutes external source crystal oscillation system I, supplies the standard concussion frequency of 32.768K, electric capacity C10, C11, crystal oscillator Y2 structures Into external source crystal oscillation system II, the standard concussion frequency of 32M is supplied;The electric capacity C5, electric capacity C6, electric capacity C7, electric capacity C8, inductance L1, inductance L2, inductance L3 and inductance L4 constitute the match circuit of balun, adjust the impedance matching of transmitting antenna, and signal is via PCB Antenna E1 launches and receives;
The detection circuit is by resistance R1, resistance R2, resistance R3, NPN triode Q1, infrared transmitting tube D2, infrared receiving tube D1 and electric capacity C4 is constituted, and the colelctor electrode of audion Q1 meets VCC and powers, when it is high level that the base stage of audion Q1 connects P10 pins, The transmitting of Q1 extremely high voltage, electric current is conducted to infrared transmitting tube D2 via R3, and infrared transmitting tube D2 work launches infrared Line, R2 connects with infrared receiving tube D1 and connect respectively by VCC and GND two ends, when the infra-red intensity that infrared receiving tube D1 is received When different, its own resistance changes, and its K pole connects P07 pins, and is AD converted sampling by MCU, judges data, electricity Appearance C4 is filter capacitor, suppresses the end peak surge voltage of D1 generations;
The warning circuit is made up of resistance R6, NPN triode Q2 and buzzer LS1, NPN triode Q2 Base stage connects P11 mouths, penetrates level and connects the positive pin of buzzer, colelctor electrode connecting resistance R6, another terminations VCC of resistance R6, when P11 is high level When, NPN triode Q2 conducting, electric current sends alarm through buzzer, buzzer startup work;
The switch voltage-stabilizing circuit is made up of chip U2, resistance R8, LED diodes D4 and high foot control S1, high foot control one end Anode is connect, the pin of a termination U2 chips the 3rd, the pin of U2 chips the 1st ground connection, the 2nd pin connects D4 positive poles, and D4 negative poles connect electricity Resistance R8, R8 other ends ground connection;When high foot control is closed, the pins of U2 the 3rd are turned on anode, obtain highest 3.7V electricity Pressure, Jing itself DC-DC voltage stabilizings obtain 3.3V voltages, externally supply as VCC, are exported by second pin;Now Second pin is high potential, drives LED normal works, LED to light, and indicates system worked well.
The charging circuit is by USB interface USB1, chip U3, electric capacity C12, resistance R5, R7, light emitting diode D3 structures Into, when USB interface connects external source USB plug, the 1st foot of USB interface is 5V high level, and the 5th foot of USB interface is ground potential, 1st foot of USB interface USB1 connects the feet of chip U3 the 4th, and the 5th foot of USB interface USB1 connects the 2nd foot of chip U2, and the 2nd of chip U2 the The indirect resistance R7 of foot and the 5th foot, R7 control programming charging current;3rd foot and the 4th foot of electric capacity C2 access chip U3 it Between, pressure stabilization function is played, the positive pole of battery connects the 4th foot such as chip, minus earth;4th foot of resistance R5 access chip U3, it is another Termination light emitting diode positive pole, the minus earth of light emitting diode D3;When USB plug is accessed, the 4th foot of chip U3 is that 5V is electric Pressure, 5V voltages constitute a path via R5 and D3, and under the driving of electric current, light emitting diode D3 work is luminous, plays instruction The effect of charging;Chip U3 the 4th foot be 5V high level when, start work, the 3rd pin output 4.2V voltages, size of current by The size of current control over the ground of 5th foot, i.e., controlled by R5 resistances size, completes the electrostrictive polymer to the foot of access chip the 4th and the 2nd foot The charge function in pond.
Battery of the present invention is 3.7V lithium battery power supplies, and effective operating time was up to 20 hours, and the drop terminal is micro- Processing module is 3.3V with the normal working voltage of PC ends monitoring system.
The MCU of the drop terminal micro treatment module of the present invention adopts the CC2540 of TI companies.
The present invention is because using said structure and monitoring method, by patient, in transfusion, all of instant messages carry out networking pipe Reason, and all information are externally shown, significantly improve HC transfusion room, the nurse station efficiency of management of hospital ward, drop Low HC transfusion room, the operating pressure of hospital ward nurse station reduces what the dangerous situations such as transfusion blood coagulation occurred Probability, with that equipment power dissipation is low, fast response time, signal intensity are high, frequency deviation is little, capacity of resisting disturbance is weak, acquisition precision is high etc. is excellent Point.
Description of the drawings
Fig. 1 is the attachment structure schematic diagram of the present invention.
Fig. 2 is the workflow diagram of mobile phone terminal monitoring system terminal node in the present invention.
Fig. 3 is the workflow diagram of PC ends monitoring system terminal node in the present invention.
Fig. 4 is the workflow diagram of mobile phone terminal monitoring system of the present invention.
Fig. 5 is the workflow diagram of PC ends monitoring system in the present invention.
Fig. 6 is the electrical schematic diagram of terminal node circuit board of the present invention.
Fig. 7 is the detection circuit module electrical schematic diagram in Fig. 6.
Fig. 8 is warning circuit modular electrical schematic diagram in Fig. 6.
Fig. 9 is drop terminal micro treatment module electrical schematic diagram in Fig. 6.
Figure 10 is Fig. 6 breaker in middle circuit module electrical schematic diagrams.
Figure 11 is power supply circuits modular electrical schematic diagram.
Reference:PC host computers 1, mobile phone 2, drop terminal node device 3, warning circuit module 4, power supply circuits module 5th, drop terminal micro treatment module 6, detection circuit module 7, on-off circuit module 8.
Specific embodiment
Below in conjunction with the accompanying drawings the present invention will be described.
As shown in drawings, a kind of transfusion real-time monitoring system, including PC host computers 1 and mobile phone 2, it is characterised in that luxuriant Fei Shi Dropper is provided with drop terminal node device 3, and the PC host computers are embedded with PC ends monitoring system, in the mobile phone mobile phone is provided with End monitoring system, the drop terminal node device is into the terminal by the terminal node circuit board group in housing and housing Node circuit plate is provided with warning circuit module 4, power supply circuits module 5, drop terminal micro treatment module 6, detection circuit module 7 With on-off circuit module 8, the warning circuit module 4, detection circuit module 7 and on-off circuit module 8 respectively with drop terminal Micro treatment module 6 is connected, and the Jing power supply circuits module 5 of the drop terminal micro treatment module 6 is powered, by the micro- place of drop terminal The power supply of the reason unified management warning circuit of module 6 module 4, detection circuit module 7 and on-off circuit module 8, it is low in energy consumption to reach Effect;
The Jing USB serial communication modules of drop terminal micro treatment module 6 are connected with the PC ends monitoring system of PC host computers, institute State mobile phone terminal Program Monitoring System to fill with the drop terminal node using the NOTIFICATION modes listened to based on protocol stack Drop terminal micro treatment module in putting carries out point-to- point communication,
The monitoring algorithm of the drop terminal micro treatment module 6 includes transfusion speed timekeeping system and alarm timer system, described The algorithm of transfusion speed timekeeping system is processed using thresholding filtering and forgetting algorithm, and its step is:Infrared tube gathers cyclopentadienyl Fei Shi Dropper and medicinal liquid drippage diffuse-reflectance and refraction effect signal and be converted to the signal of telecommunication, drop terminal micro treatment module charge Up and down fluctuation is 0.1-0.3V under circuit electric power thus supplied, that is, it is 2-8% to detect change in voltage, because each drop signal is all deposited End peak is impacted at one, is directly AD converted signal for the process of this signal is adopted, by the telecommunications count for collecting Value is amplified, and sets two threshold values, when higher limit is broken through, mark position TRUE, and mark position when breaking through lower limit FALSE, flag bit is designated as detecting a drop when converting twice;If the end peak impact of signal is detected, according to liquid The timestamp information of drop is compared, and judges drop frequency, is omitted less than the drop information of intervals;
The algorithm steps of the alarm timer system are:When often detecting drop signal on drop terminal micro treatment module, report to the police Flag bit resets, and timekeeping system two resets;And by setting warning duration, when long-time can't detect drop signal, timing Two timing length of system exceed the warning duration of setting, and warning mark position is hung up, and driven by program warning circuit module sends alarm Information;When drop signal is detected again, by resetting to warning mark position, can sound all clear;
The algorithm steps of the drop terminal micro treatment module are:Drop terminal micro treatment module when drop signal is detected, Timestamp is intercepted, and compares last timestamp, calculate time difference QUOTE between two drop signals , and ask for Meansigma methodss QUOTE of adjacent ten drops interval time , and have following equation to draw transfusion speed:
QUOTE (Formula 3)
And transfusion total amount information is encapsulated in drop terminal micro treatment module with No. ID of transfusion speed and terminal node,
When the monitoring system poll instruction of PC ends is received, the packet in drop terminal micro treatment module is uploaded to the monitoring of PC ends System, patient cases' information that doctor passes through input in the monitoring system of PC ends, using MAC IEEE addresses are directly called out, completes blind Connection, it is possible to while at least 3 drop terminal node devices of effectively connection, and connect reading one by one by the way of poll inquiry The effective information on terminal node is taken, single terminal node device connection reading information to the time for disconnecting is less than The information gathering of 100 terminal nodes, efficient quick can be completed in 5ms, i.e., 1 second;
When inquiring about in mobile phone terminal monitoring system, the mobile phone terminal monitoring system receives what drop terminal micro treatment module was uploaded Each drop timestamp and drop total amount in packet in drop terminal micro treatment module, and calculate transfusion speed, defeated Liquid residual liquid quantity, transfusion remaining time, whether drip and stop and information about power, doctor or nurse or entourage is passed through The mobile phone terminal monitoring system monitor in real time transfusion state, significantly improves the safety of patient.
The specific algorithm step of PC ends of the present invention monitoring system is:
First, the number of drops that the every 1ml of total amount and institute's transfusion that infuses is included is manually entered,
PC ends monitoring system reads the packet of drop terminal micro treatment module, No. ID in the packet that will be read first and number Compare according to the medical record number in storehouse, and the drop total amount information and transfusion speed information in poll read data packet, and supervised by PC ends The transfusion total amount information and droplet size information arranged in control system draws and formula is calculated as below:
QUOTE (Formula 3)
The wherein QUOTE of formula 3 Present infusion surpluses are represented, unit is ml;
QUOTE Plan transfusion total amount is represented, unit is ml;
Num represents the transfusion drop sum obtained from terminal node, and num/ml is the drop that every 1ml of institute's transfusion is included Number;
To calculate present infusion surpluses information, to reach the effect of unified management;
When PC ends monitoring system monitors to infuse total amount residue less than 20ml, then send alarm, prompting nurse carry out pulling out pin or Change section operation;Or, when running voltage is detected less than 3.3V, by drop terminal micro treatment module, PC host computers are sent out Go out the low alarm of electricity, remind staff to be charged to battery in time.
When PC host computers of the present invention are started shooting every time or every 5 minutes, by PC ends monitoring system to outside confession Electric pin is AD converted, be beneficial to reduction MCU computing loads, the actual measuring and calculating of Jing, when battery power for critical point 3.2V when, just Often can hold on more than 120 minutes under working condition.
The specific algorithm step of mobile phone terminal monitoring system of the present invention is:The input transfusion total amount first in cell phone system The number of drops included with every ml, when the data uploaded in detecting drop terminal MCU single-chip microcomputer are surrounded by drop signal, Automatic Program intercepts timestamp, and drop total amount is added up, and calculates transfusion speed information, specific algorithm by monitoring system It is as follows:
QUOTE (Formula 1)
The wherein QUOTE of formula 1 For the volume of transfusion per minute, unit is ml/min,
QUOTE For the difference of the timestamp of Qian Hou two drop,
Num/ml is the number of drops that every 1ml of institute's transfusion is included;
Following information is drawn by the volume of every drop of liquid:
QUOTE (Formula 2)
The wherein QUOTE of formula 2 Present infusion surpluses are represented, unit is ml;
QUOTE Plan transfusion total amount is represented, unit is ml.
Num represents the transfusion drop sum obtained from terminal node;
Num/ml is the number of drops that every 1ml of institute's transfusion is included,
So that patient or family numbers of patients are by the mobile phone real time inspection transfusion condition of oneself.
Computer adapter is provided between PC host computers of the present invention and drop terminal node device, the computer adapter is adopted With MCU the and BLE host protocol stacks of CC2540, it is beneficial to when the packet Jing MCU in drop terminal micro treatment module are sent to PC In the concrete connection procedure of end monitoring system, by transferring protocol stack main frame connectivity function function, directly by MAC IEEE addresses Write, and the IEEE address styles and IEEE address sizes of terminal node are being set before, mandatory connection is completed, i.e., blind company Connect, so make connection procedure abbreviation for " connection-communication-disconnect all ", eliminate it is troublesome " scanning-pairing-connection- The cumbersome process of communication-disconnect ", saves for 95% time.
Drop terminal micro treatment module of the present invention is by electric capacity C1, electric capacity C2, electric capacity C3, electric capacity C10, electric capacity C11, chip U1 and crystal oscillator Y1, Y2 constitute MCU work systems, and the electric capacity C3 is responsible for the in-line power voltage stabilizing of chip U1, electric capacity C1, C2, crystal oscillator Y1 constitutes external source crystal oscillation system I, supplies the standard concussion frequency of 32.768K, electric capacity C10, C11, crystal oscillator Y2 structures Into external source crystal oscillation system II, the standard concussion frequency of 32M is supplied;The electric capacity C5, electric capacity C6, electric capacity C7, electric capacity C8, inductance L1, inductance L2, inductance L3 and inductance L4 constitute the match circuit of balun, adjust the impedance matching of transmitting antenna, and signal is via PCB Antenna E1 launches and receives;
The detection circuit is by resistance R1, resistance R2, resistance R3, NPN triode Q1, infrared transmitting tube D2, infrared receiving tube D1 and electric capacity C4 is constituted, and the colelctor electrode of audion Q1 meets VCC and powers, when it is high level that the base stage of audion Q1 connects P10 pins, The transmitting of Q1 extremely high voltage, electric current is conducted to infrared transmitting tube D2 via R3, and infrared transmitting tube D2 work launches infrared Line, R2 connects with infrared receiving tube D1 and connect respectively by VCC and GND two ends, when the infra-red intensity that infrared receiving tube D1 is received When different, its own resistance changes, and its K pole connects P07 pins, and is AD converted sampling by MCU, judges data, electricity Appearance C4 is filter capacitor, suppresses the end peak surge voltage of D1 generations;
The warning circuit is made up of resistance R6, NPN triode Q2 and buzzer LS1, NPN triode Q2 Base stage connects P11 mouths, penetrates level and connects the positive pin of buzzer, colelctor electrode connecting resistance R6, another terminations VCC of resistance R6, when P11 is high level When, NPN triode Q2 conducting, electric current sends alarm through buzzer, buzzer startup work;
The switch voltage-stabilizing circuit is made up of chip U2, resistance R8, LED diodes D4 and high foot control S1, high foot control one end Anode is connect, the pin of a termination U2 chips the 3rd, the pin of U2 chips the 1st ground connection, the 2nd pin connects D4 positive poles, and D4 negative poles connect electricity Resistance R8, R8 other ends ground connection;When high foot control is closed, the pins of U2 the 3rd are turned on anode, obtain highest 3.7V electricity Pressure, Jing itself DC-DC voltage stabilizings obtain 3.3V voltages, externally supply as VCC, are exported by second pin;Now Second pin is high potential, drives LED normal works, LED to light, and indicates system worked well.
The charging circuit is by USB interface USB1, chip U3, electric capacity C12, resistance R5, R7, light emitting diode D3 structures Into, when USB interface connects external source USB plug, the 1st foot of USB interface is 5V high level, and the 5th foot of USB interface is ground potential, 1st foot of USB interface USB1 connects the feet of chip U3 the 4th, and the 5th foot of USB interface USB1 connects the 2nd foot of chip U2, and the 2nd of chip U2 the The indirect resistance R7 of foot and the 5th foot, R7 control programming charging current;3rd foot and the 4th foot of electric capacity C2 access chip U3 it Between, pressure stabilization function is played, the positive pole of battery connects the 4th foot such as chip, minus earth;4th foot of resistance R5 access chip U3, it is another Termination light emitting diode positive pole, the minus earth of light emitting diode D3;When USB plug is accessed, the 4th foot of chip U3 is that 5V is electric Pressure, 5V voltages constitute a path via R5 and D3, and under the driving of electric current, light emitting diode D3 work is luminous, plays instruction The effect of charging;Chip U3 the 4th foot be 5V high level when, start work, the 3rd pin output 4.2V voltages, size of current by The size of current control over the ground of 5th foot, i.e., controlled by R5 resistances size, completes the electrostrictive polymer to the foot of access chip the 4th and the 2nd foot The charge function in pond.
Battery of the present invention is 3.7V lithium battery power supplies, and effective operating time was up to 20 hours, and the drop terminal is micro- Processing module is 3.3V with the normal working voltage of PC ends monitoring system.
The MCU of the drop terminal micro treatment module of the present invention adopts the CC2540 of TI companies.
The present invention is first fixed on drop terminal node device Jing housings on Murphy type burette, institute in Clinical practice State drop terminal node device Jing computer adapters to be connected with the PC host computers, by way of scanning case bar code, will Case information is embedded in the PC host computers of hospital, then instant messages during patient fluid infusion are listened to by protocol stack NOTIFICATION modes carry out point-to- point communication with the mobile phone terminal Program Monitoring System, the PC monitoring on the PC host computers System, can be while at least 3 drop terminal node devices of effectively connection, using poll inquiry using directly calling out IEEE addresses Mode connect one by one read drop terminal node device on effective information, to single drop terminal node device connection read Information is to the time for disconnecting less than the information gathering that 100 terminal units can be completed in 5ms, i.e., 1 second, and colleges and universities are fast It is prompt;The computer adapter using CC2540 MCU and BLE host protocol stacks, due to each CC2540 when dispatching from the factory band There are the globally unique IEEE addresses of 6, and this MAC IEEE address is entrained in when terminal node sends broadcast Among broadcast message, in being stored in the packet of drop terminal micro treatment module of PC ends monitoring system, and as unique sign point With No. ID.
When packet Jing drop terminals MCU in drop terminal micro treatment module are sent to the concrete connection of PC ends monitoring system During, by transferring protocol stack main frame connectivity function enum connect (uint16 MAC, uint8 len, uint8 Type), directly MAC IEEE addresses are write, and IEEE address styles in drop terminal micro treatment module is set before With IEEE address sizes, mandatory connection is completed, i.e., blind connection so makes connection procedure abbreviation for " connection-communication-disconnect It is all ", the cumbersome process of troublesome " scanning-pairing-connection-communication-disconnect " is eliminated, save for 95% time;
Dropping liquid in Murphy type burette starts, diffuse-reflectance and refraction effect that infrared tube collection Murphy type burette and medicinal liquid are dripped Signal and be converted to the signal of telecommunication, drop terminal micro treatment module in the case of charging circuit is powered as 3.3V up and down fluctuation be 0.2V, that is, it is 6% to detect change in voltage, because each drop signal all has an impact end peak, for the place of this signal Using being directly AD converted signal, sample frequency is 20Hz to reason, and the signal of telecommunication numerical value for collecting is amplified, and sets two Individual threshold value, when higher limit is broken through, mark position TRUE, mark position FALSE when breaking through lower limit, flag bit is through twice During conversion, it is designated as detecting a drop;When the employing frequency using 20Hz, can effectively be neglected according to Sampling Theorem The end peak impact of signal;When the end peak for detecting signal impacts, then compared according to the timestamp information of drop, judge drop frequency Rate, is omitted less than the drop information of intervals, and the signal of telecommunication collected due to infrared tube is without hardware electricity Road Filtering Processing, and directly carry out the employing of data, significantly reduces the power consumption of equipment, and signal intensity is big, capacity of resisting disturbance By force, acquisition precision is high.
When 20S time detecting is less than drop signal, two timing length of timekeeping system exceed the warning duration of setting, report to the police Flag bit is hung up, and driven by program warning circuit module sends a warning;When drop signal is detected again, by reporting to the police Flag bit resets, and sounds all clear;
When the monitoring system poll instruction of PC ends is received, the packet in drop terminal micro treatment module is uploaded to the monitoring of PC ends System, patient cases' information that doctor passes through input in the monitoring system of PC ends, using MAC IEEE addresses are directly called out, completes blind Connection, it is possible to while at least 3 drop terminal node devices of effectively connection, and connect reading one by one by the way of poll inquiry The effective information on terminal node is taken, single terminal node device connection reading information to the time for disconnecting is less than The information gathering of 100 terminal nodes, efficient quick can be completed in 5ms, i.e., 1 second.
When inquiring about in mobile phone terminal monitoring system, the mobile phone terminal monitoring system is received on drop terminal micro treatment module Each drop timestamp and drop total amount in the packet of biography, and calculate transfusion speed, transfusion liquid surpluses, infuse surplus The remaining time, whether drip and stop and information about power, enable doctor or nurse or entourage by the mobile phone terminal monitoring system Monitor in real time transfusion state, when mobile phone terminal monitoring system monitors to infuse total amount residue less than 20ml, then sends alarm, reminds Patient pulls out pin or changes section, significantly improves the safety of patient,
When running voltage is detected less than 3.3V, the low information of electricity is uploaded on PC by drop terminal micro treatment module PC ends monitoring system in the machine of position, the low alarm of electricity is sent to PC host computers, points out medical personnel to change battery.
The present invention is because using said structure and monitoring method, by patient, in transfusion, all of instant messages are networked Management, and all information is externally shown, significantly improves HC transfusion room, the nurse station efficiency of management of hospital ward, HC transfusion room is reduced, the operating pressure of hospital ward nurse station reduces the dangerous situation generation such as transfusion blood coagulation Probability, with equipment power dissipation is low, fast response time, signal intensity are high, frequency deviation is little, capacity of resisting disturbance is weak, acquisition precision is high etc. Advantage.

Claims (10)

1. a kind of transfusion real-time monitoring system, including PC host computers and mobile phone, it is characterised in that Murphy type burette is provided with drop Terminal node device, the PC host computers are embedded with PC ends monitoring system, and mobile phone terminal monitoring system is provided with the mobile phone, described Drop terminal node device is into the terminal node circuit board is provided with by the terminal node circuit board group in housing and housing Warning circuit module, power supply circuits module, drop terminal micro treatment module, detection circuit module and on-off circuit module, it is described Warning circuit module, detection circuit module and on-off circuit module are connected respectively with drop terminal micro treatment module, the liquid Drop terminal micro treatment module Jing power supply circuits module for power supply, by drop terminal micro treatment module warning circuit mould is managed collectively The power supply of block, detection circuit module and on-off circuit module;
The drop terminal micro treatment module Jing USB serial communication modules are connected with the PC ends monitoring system of PC host computers, institute State mobile phone terminal Program Monitoring System to fill with the drop terminal node using the NOTIFICATION modes listened to based on protocol stack Drop terminal micro treatment module in putting carries out point-to- point communication,
The monitoring algorithm of the drop terminal micro treatment module includes transfusion speed timekeeping system and alarm timer system, described defeated The algorithm of liquid speed degree timekeeping system is processed using thresholding filtering and forgetting algorithm, and its step is:Infrared tube gathers cyclopentadienyl Fei Shi drops Manage the signal of the diffuse-reflectance and refraction effect dripped with medicinal liquid and be converted to the signal of telecommunication, drop terminal micro treatment module is in the electricity that charges Up and down fluctuation is 0.1-0.3V under the electric power thus supplied of road, that is, it is 2-8% to detect change in voltage, because each drop signal is all present One impact end peak, is directly AD converted signal for the process of this signal is adopted, by the signal of telecommunication numerical value for collecting Amplify, and set two threshold values, when higher limit is broken through, mark position TRUE, mark position FALSE when breaking through lower limit, Flag bit is designated as detecting a drop when converting twice;If detect signal end peak impact, according to drop when Between stab information compare, judge drop frequency, be omitted less than the drop information of intervals;
The algorithm steps of the alarm timer system are:When often detecting drop signal on drop terminal micro treatment module, report to the police Flag bit resets, and timekeeping system two resets;And by setting warning duration, when long-time can't detect drop signal, timing Two timing length of system exceed the warning duration of setting, and warning mark position is hung up, and driven by program warning circuit module sends alarm Information;When drop signal is detected again, by resetting to warning mark position, can sound all clear;
The algorithm steps of the drop terminal micro treatment module are:Drop terminal micro treatment module when drop signal is detected, Timestamp is intercepted, and compares last timestamp, calculate the time difference between two drop signals, and ask for adjacent ten The meansigma methodss of drop interval time, and have following equation to draw transfusion speed:
(Formula 3)
And transfusion total amount information is encapsulated in drop terminal micro treatment module with No. ID of transfusion speed and terminal node,
When the monitoring system poll instruction of PC ends is received, the packet in drop terminal micro treatment module is uploaded to the monitoring of PC ends System, patient cases' information that doctor passes through input in the monitoring system of PC ends, using directly cry MAC IEEE addresses, it is possible to While at least 2 drop terminal node devices of effectively connection, and connect reading terminals node one by one by the way of poll inquiry On effective information;
When inquiring about in mobile phone terminal monitoring system, the mobile phone terminal monitoring system receives what drop terminal micro treatment module was uploaded Each drop timestamp and drop total amount in packet in drop terminal micro treatment module, and calculate transfusion speed, defeated Liquid residual liquid quantity, transfusion remaining time, whether drip and stop and information about power, doctor or nurse or entourage is passed through The mobile phone terminal monitoring system monitor in real time transfusion state.
2. a kind of transfusion real-time monitoring system according to claim 1, it is characterised in that the tool of PC ends monitoring system Body algorithm steps are:
First, the number of drops that the every 1ml of total amount and institute's transfusion that infuses is included is manually entered,
PC ends monitoring system reads the packet of drop terminal micro treatment module, No. ID in the packet that will be read first and number Compare according to the medical record number in storehouse, and the drop total amount information and transfusion speed information in poll read data packet, and supervised by PC ends The transfusion total amount information and droplet size information arranged in control system draws and formula is calculated as below:
(Formula 3)
Wherein formula 3Present infusion surpluses are represented, unit is ml;
Plan transfusion total amount is represented, unit is ml;
Num represents the transfusion drop sum obtained from terminal node, and num/ml is the drop that every 1ml of institute's transfusion is included Number;
To calculate present infusion surpluses information, to reach the effect of unified management;
When PC ends monitoring system monitors to infuse total amount residue less than 20ml, then send alarm, prompting nurse carry out pulling out pin or Change section operation;Or, when running voltage is detected less than 3.3V, by drop terminal micro treatment module, PC host computers are sent out Go out the low alarm of electricity, remind staff to be charged to battery in time.
3. a kind of transfusion real-time monitoring system according to claim 2, it is characterised in that the PC host computers are started shooting every time When or every 5 minutes, outside energization pins are AD converted by PC ends monitoring system.
4. a kind of transfusion real-time monitoring system according to claim 1 and 2, it is characterised in that the mobile phone terminal monitoring system Specific algorithm step be:Input transfusion total amount and the number of drops that included per ml in systems first, when detecting drop end When the data uploaded in the MCU single-chip microcomputers of end are surrounded by drop signal, Automatic Program intercepts timestamp, and drop total amount is tired out Plus, and transfusion speed information is calculated by monitoring system, specific algorithm is as follows:
(Formula 1)
Wherein formula 1For the volume of transfusion per minute, unit is ml/min,
For the difference of the timestamp of Qian Hou two drop,
Num/ml is the number of drops that every 1ml of institute's transfusion is included;
Following information is drawn by the volume of every drop of liquid:
(Formula 2)
Wherein formula 2Present infusion surpluses are represented, unit is ml;
Plan transfusion total amount is represented, unit is ml.
5.Num represents the transfusion drop sum obtained from terminal node;
Num/ml is the number of drops that every 1ml of institute's transfusion is included,
So that patient or family numbers of patients are by the mobile phone real time inspection transfusion condition of oneself.
6. a kind of transfusion real-time monitoring system according to claim 1, it is characterised in that the PC host computers and drop end Computer adapter is provided between end node device, the computer adapter adopts MCU the and BLE host protocol stacks of CC2540.
7. a kind of transfusion real-time monitoring system according to claim 1, it is characterised in that the drop terminal microprocessor mould Block is that by electric capacity C1, electric capacity C2, electric capacity C3, electric capacity C10, electric capacity C11, chip U1 and crystal oscillator Y1, Y2 constitute MCU job families System, the electric capacity C3 is responsible for the in-line power voltage stabilizing of chip U1, electric capacity C1, C2, and crystal oscillator Y1 constitutes external source crystal oscillation system I, supply The standard concussion frequency of 32.768K, electric capacity C10, C11, crystal oscillator Y2 constitutes external source crystal oscillation system II, supplies the standard concussion of 32M Frequency;The electric capacity C5, electric capacity C6, electric capacity C7, electric capacity C8, inductance L1, inductance L2, inductance L3 and inductance L4 constitute balun With circuit, the impedance matching of transmitting antenna is adjusted, signal is launched and received via PCB antenna E1;
The detection circuit is by resistance R1, resistance R2, resistance R3, NPN triode Q1, infrared transmitting tube D2, infrared receiving tube D1 and electric capacity C4 is constituted, and the colelctor electrode of audion Q1 meets VCC and powers, when it is high level that the base stage of audion Q1 connects P10 pins, The transmitting of Q1 extremely high voltage, electric current is conducted to infrared transmitting tube D2 via R3, and infrared transmitting tube D2 work launches infrared Line, R2 connects with infrared receiving tube D1 and connect respectively by VCC and GND two ends, when the infra-red intensity that infrared receiving tube D1 is received When different, its own resistance changes, and its K pole connects P07 pins, and is AD converted sampling by MCU, judges data, electricity Appearance C4 is filter capacitor, suppresses the end peak surge voltage of D1 generations;
The warning circuit is made up of resistance R6, NPN triode Q2 and buzzer LS1, NPN triode Q2 Base stage connects P11 mouths, penetrates level and connects the positive pin of buzzer, colelctor electrode connecting resistance R6, another terminations VCC of resistance R6, when P11 is high level When, NPN triode Q2 conducting, electric current sends alarm through buzzer, buzzer startup work;
The switch voltage-stabilizing circuit is made up of chip U2, resistance R8, LED diodes D4 and high foot control S1, high foot control one end Anode is connect, the pin of a termination U2 chips the 3rd, the pin of U2 chips the 1st ground connection, the 2nd pin connects D4 positive poles, and D4 negative poles connect electricity Resistance R8, R8 other ends ground connection;When high foot control is closed, the pins of U2 the 3rd are turned on anode, obtain highest 3.7V electricity Pressure, Jing itself DC-DC voltage stabilizings obtain 3.3V voltages, externally supply as VCC, are exported by second pin;Now Second pin is high potential, drives LED normal works, LED to light, and indicates system worked well.
8. charging circuit described in is that, by USB interface USB1, chip U3, electric capacity C12, resistance R5, R7, light emitting diode D3 is constituted, When USB interface connects external source USB plug, the 1st foot of USB interface is 5V high level, and the 5th foot of USB interface is ground potential, and USB connects 1st foot of mouthful USB1 connects the feet of chip U3 the 4th, and the 5th foot of USB interface USB1 connects the 2nd foot of chip U2, the 2nd foot of chip U2 with The indirect resistance R7 of the 5th foot, R7 control programming charging current;Between 3rd foot and the 4th foot of electric capacity C2 access chip U3, Pressure stabilization function is played, the positive pole of battery connects the 4th foot such as chip, minus earth;4th foot of resistance R5 access chip U3, the other end Sending and receiving optical diode positive pole, the minus earth of light emitting diode D3;When USB plug is accessed, the 4th foot of chip U3 is that 5V is electric Pressure, 5V voltages constitute a path via R5 and D3, and under the driving of electric current, light emitting diode D3 work is luminous, plays instruction The effect of charging;Chip U3 the 4th foot be 5V high level when, start work, the 3rd pin output 4.2V voltages, size of current by The size of current control over the ground of 5th foot, i.e., controlled by R5 resistances size, completes the electrostrictive polymer to the foot of access chip the 4th and the 2nd foot The charge function in pond.
9. a kind of transfusion real-time monitoring system according to claim 6, it is characterised in that the battery is 3.7V lithium batteries Power supply, the drop terminal micro treatment module is 3.3V with the normal working voltage of PC ends monitoring system.
10. a kind of transfusion real-time monitoring system according to claim 6, it is characterised in that the micro- place of the drop terminal The MCU of reason module adopts the CC2540 of TI companies.
CN201611198822.0A 2016-12-22 2016-12-22 Real-time monitoring system for transfusion Pending CN106668985A (en)

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Application publication date: 20170517