CN106620882A - Artificial bone structure having density gradient - Google Patents
Artificial bone structure having density gradient Download PDFInfo
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- CN106620882A CN106620882A CN201611035833.7A CN201611035833A CN106620882A CN 106620882 A CN106620882 A CN 106620882A CN 201611035833 A CN201611035833 A CN 201611035833A CN 106620882 A CN106620882 A CN 106620882A
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- artificial bone
- sucking
- density
- linkage section
- aperture
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/025—Other specific inorganic materials not covered by A61L27/04 - A61L27/12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
- A61F2002/30011—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis differing in porosity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30772—Apertures or holes, e.g. of circular cross section
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0023—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in porosity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Abstract
The invention discloses an artificial bone structure having a density gradient. The artificial bone structure comprises an artificial bone body with a preset shape, and a plurality of absorption holes formed in the artificial bone body, wherein a first connection section of the artificial bone body is connected with a broken bone at the side needing a higher absorption rate and is absorbed by the broken bone at the side needing the higher absorption rate; a second connection section of the artificial bone body is connected with a broken bone at the side needing a lower absorption rate and is absorbed by the broken bone at the side needing the lower absorption rate; the density of the absorption holes formed in the first connection section is larger than that of the absorption holes formed in the second connection section; the artificial bone body is a calcium sulfate mixture or a calcium phosphate mixture; the density of the absorption holes formed in the artificial bone body is proportional to the absorption rate needed at the position; the apertures of the absorption holes formed in the artificial bone body is proportional to the absorption rate needed at the position. Therefore, the artificial bone structure can regulate the absorption speed of an artificial bone according to the difference of wound healing surfaces, so that the structural strength and bone healing effect of the artificial bone are guaranteed.
Description
Technical field
The invention belongs to a kind of medical instruments, and in particular to a kind of artificial bone structure with density gradient.
Background technology
Artificial bone (Artificial Bone) refers to the artificial bio-membrane that can be substituted human body bone or repair bone tissue defect
Material, has in modern orthopaedic medical treatment and is widely used.In open wedge osteotomy, the stability and bone at osteotomy position heal
Conjunction is the key factor for affecting early rehabilitation and complication rate after operation in patients.Traditional open wedge osteotomy is thought, is opened
Put wedge shape base needs bone grafting, the past bone grafting to can select autologous bone, allograph bone, three kinds of materials of absorbable artificial bone more than 1.5cm.
Absorbable artificial bone bone grafting have it is easy to use, without damaging for area and complication, source is sufficient, infection is closed without allosome bone photo and arrange
The advantage of the aspects such as different the problems such as, therefore clinically it is increasingly subject to favor.But, it is strong to there is structure in existing absorbable artificial bone
Degree it is weaker, by infiltration rate it is uncontrollable the problems such as.If artificial bone is absorbed too early, local strength is newborn by rapid decrease
Bone has little time creeping substitution, then easily cause local strength weak；If artificial bone is excessively slow by infiltration rate, area of new bone is hindered
Bone creeping substitution, is also unfavorable for bone healing.
Therefore it provides a kind of artificial bone structure with density gradient, to can be according to the discrepancy adjustment of more face position
The infiltration rate of artificial bone, so as to ensure the structural strength and bone healing effect of artificial bone, just becomes those skilled in the art
Problem demanding prompt solution.
The content of the invention
The present invention is intended to provide a kind of artificial bone structure with density gradient, to can be according to the difference of more face position
The infiltration rate of adjustment artificial bone, so as to ensure the structural strength and bone healing effect of artificial bone, just becomes art technology
Personnel's problem demanding prompt solution.
For achieving the above object, the artificial bone structure with density gradient provided by the present invention, including with default shape
The artificial bone body of shape and some suckings being opened on the artificial bone body, the first linkage section of the artificial bone body
The side knochenbruch higher with required absorption rate is connected and by side knochenbruch absorption, its second linkage section and required absorption rate
Relatively low side knochenbruch is connected and is absorbed by the side knochenbruch；The density of the sucking on first linkage section is more than institute
The density of the sucking on the second linkage section is stated, the artificial bone body is mixture of calcium sulfate or calcium phosphate mixture；
The density of the sucking on the artificial bone body is proportional with the required absorption rate at this, the suction on the artificial bone body
The aperture of batter is directly proportional to the required absorption rate at this.
Further, the aperture of the sucking on first linkage section is more than the absorption on second linkage section
The aperture in hole.
Further, the aperture of the sucking on first linkage section and the suction on second linkage section
The aperture of batter is between 100 microns -400 microns with the formal distribution of bore diameter gradient.
Further, the density of the sucking on first linkage section and the suction on second linkage section
The density of batter is between 0-200 every square centimeter with the formal distribution of density gradient.
Further, the multiple described sucking on same linkage section is distributed in the artificial bone body.
Further, first linkage section is mixture of calcium sulfate, and second linkage section is calcium phosphate mixture.
Further, the preset shape is wedge shape, rectangle, disk or sphere.
Artificial bone structure with density gradient provided by the present invention include the artificial bone body with preset shape and
The some suckings being opened on the artificial bone body, the first linkage section of the artificial bone body and required absorption rate compared with
High side knochenbruch is connected and is absorbed by the side knochenbruch, its second linkage section side knochenbruch phase relatively low with required absorption rate
Even and by the side knochenbruch absorb；The density of the sucking on first linkage section is more than on second linkage section
The density of the sucking, the artificial bone body is mixture of calcium sulfate or calcium phosphate mixture；On the artificial bone body
Sucking density it is proportional with the required absorption rate at this, the aperture of the sucking on the artificial bone body with this at
Required absorption rate be directly proportional.
It is to ensure suction everywhere due to the difference of the absorption rate required for knochenbruch knochenbruch everywhere with diverse location
Receive speed equilibrium, density and aperture of the artificial bone structure by the sucking of control different parts, it is allowed to which aperture is big, sucking
The big part of density takes the lead in being absorbed, and the tight section that aperture is little, absorption hole density is little delays to be absorbed.For example：Opening
At in larger distance, the slower cortex bone that heals, the sucking aperture of artificial bone is reduced, increase sucking density of setting, improve it
Consistency, delays it by infiltration rate；And open distance is less, healing at cancellous bone, improves the absorption of artificial bone faster
Hole aperture, reduces sucking density of setting, reduces its consistency, accelerates it by infiltration rate, it is allowed to which sclerotin Quick-climbing is substituted.
Specifically, in order to control artificial bone resorption rate, need to meet following condition simultaneously：I.e. artificial bone thickness is the absorption of thickness of thin
Hurry up, otherwise absorb slow；Artificial bone aperture is that the big absorption in aperture is fast, otherwise absorbs slow；Artificial bone hole density is high containing hole density
Absorption it is fast, otherwise absorb slow；Artificial bone component is that the high absorption of calcium carbonate concentration is fast, the high absorption of phosphoric acid calcium concentration
Slowly.So, the artificial bone structure can be artificial so as to ensure that according to the infiltration rate of the discrepancy adjustment artificial bone of more face position
The structural strength and bone healing effect of bone.
Description of the drawings
In order to be illustrated more clearly that the specific embodiment of the invention or technical scheme of the prior art, below will be to concrete
The accompanying drawing to be used needed for embodiment or description of the prior art is briefly described.
Fig. 1 is a kind of partial structural diagram of specific embodiment of artificial bone structure provided by the present invention.
Description of reference numerals：
1- artificial bone bodies
2- suckings
Specific embodiment
Embodiments of the invention are described below in detail, the example of the embodiment is shown in the drawings, wherein from start to finish
Same or similar label represents same or similar element or the element with same or like function.Below with reference to attached
The embodiment of figure description is exemplary, it is intended to for explaining the present invention, and be not considered as limiting the invention.
Fig. 1 is refer to, Fig. 1 is that a kind of partial structurtes of specific embodiment of artificial bone structure provided by the present invention are illustrated
Figure.
In a kind of specific embodiment, the artificial bone structure with density gradient provided by the present invention includes having in advance
If the artificial bone body 1 of shape and some suckings 2 being opened on the artificial bone body 1, the of the artificial bone body 1
The one linkage section side knochenbruch higher with required absorption rate is connected and is absorbed by side knochenbruch, its second linkage section with it is required
The relatively low side knochenbruch of absorption rate is connected and is absorbed by the side knochenbruch；The sucking 2 on first linkage section it is close
More than the density of the sucking 2 on second linkage section, the artificial bone body 1 is mixture of calcium sulfate or phosphoric acid to degree
Calcium compound；The density of the sucking 2 on the artificial bone body 1 is proportional with the required absorption rate at this, described artificial
The aperture of the sucking 2 on bone body 1 is directly proportional to the required absorption rate at this.
It is to ensure suction everywhere due to the difference of the absorption rate required for knochenbruch knochenbruch everywhere with diverse location
Receipts speed is balanced, density and aperture of the artificial bone structure by the sucking 2 of control different parts, it is allowed to which aperture is big, absorption
The big part of the density of hole 2 takes the lead in being absorbed, and the tight section that aperture is little, the density of sucking 2 is little delays to be absorbed.For example：
At the cortex bone that open distance is larger, healing is slower, the aperture of sucking 2 of artificial bone is reduced, increases the density of setting of sucking 2,
Its consistency is improved, delays it by infiltration rate；And open distance is less, healing at cancellous bone, improves artificial bone faster
The aperture of sucking 2, reduce the density of setting of sucking 2, reduce its consistency, accelerate it by infiltration rate, it is allowed to which sclerotin is quick
Creeping substitution.Specifically, in order to control artificial bone resorption rate, need to meet following condition simultaneously：I.e. artificial bone thickness is thickness
The thin absorption of degree is fast, otherwise absorbs slow；Artificial bone aperture is that the big absorption in aperture is fast, otherwise absorbs slow；Artificial bone hole density is
It is fast containing the high absorption of hole density, on the contrary absorb slow；Artificial bone component is that the high absorption of calcium carbonate concentration is fast, phosphoric acid calcium concentration
High absorption is slow.So, the artificial bone structure can be according to the infiltration rate of the discrepancy adjustment artificial bone of more face position, so as to protect
The structural strength and bone healing effect of artificial bone are demonstrate,proved.
In order to the absorption rate for realizing the first linkage section corresponding position it is larger, the sucking 2 on first linkage section
Aperture more than the aperture of the sucking 2 on second linkage section, further control absorption rate by adjusting aperture, with
Ensure bone healing effect.
Specifically, the aperture of the sucking on first linkage section and the absorption on second linkage section
The aperture in hole is between 100 microns -400 microns with the formal distribution of bore diameter gradient.Absorption on first linkage section
The density of the density in hole and the sucking on second linkage section is between 0-200 every square centimeter with density gradient
Formal distribution.To ensure optimal assimilation effect.
It should be appreciated that the density value of the aperture value of sucking 2 and sucking 2 should be true according to the position at artificial bone place
It is fixed, to ensure that absorption rate is defined.
In order to ensure the uniform absorption on same section, the multiple described sucking 2 on same linkage section is distributed in
The artificial bone body 1, because the absorption rate of calcium sulfate is high, requires that the first higher linkage section is calcium sulfate in absorption rate
Mixture, and the absorption rate of calcium phosphate is relatively low, and relatively low second linkage section is required for calcium phosphate mixing in absorption rate
Thing, will pass through material further adjustment absorption rate is selected.
The preset shape of the artificial bone body 1 can be wedge shape, rectangle, disk or sphere, to adapt to different knochenbruch positions
Put, match with knochenbruch position.
In this specific embodiment, the formula of artificial bone structure provided by the present invention is the mixed of calcium sulfate and calcium phosphate
Compound, because calcium sulfate infiltration rate is faster than calcium phosphate, the concentration of both different parts is different；Used in different knochenbruch positions
When putting, the artificial bone body 1 can have different profiles：As wedge shape can be used for wedge osteotomy position, rectangle can be used for rectangle
Cranial defect position, disk can be used for sheet Cranial defect position, and sphere can be used for acetabular bone fornix shape Cranial defect；The artificial bone structure is
Loose structure, i.e., open up some suckings 2 on artificial bone body 1, as needed, the intensive journey of the sucking 2 of different parts
Degree (proportional from infiltration rate) and aperture (proportional with infiltration rate) can be different；The material of artificial bone can gradually be inhaled by human body
Receive, different material prescription, the dense degree in different holes and aperture produce can absorbed speed it is different；Calcium sulphate content is dense
The position that degree is high, the dense degree in hole is high and aperture is big can be fast by infiltration rate, and calcium phosphate content concentration is high, the dense degree in hole
The low and little position in aperture can be slow by infiltration rate.
In describing the invention, it is to be understood that term " " center ", " longitudinal direction ", " horizontal ", " length ", " width ",
" thickness ", " on ", D score, "front", "rear", "left", "right", " vertical ", " level ", " top ", " bottom " " interior ", " outward ", " up time
The orientation or position relationship of the instruction such as pin ", " counterclockwise ", " axial direction ", " radial direction ", " circumference " be based on orientation shown in the drawings or
Position relationship, is for only for ease of the description present invention and simplifies description, rather than indicates or imply that the device or element of indication must
With specific orientation, with specific azimuth configuration and operation, therefore must be not considered as limiting the invention.
Additionally, term " first ", " second " are only used for describing purpose, and it is not intended that indicating or implying relative importance
Or the implicit quantity for indicating indicated technical characteristic.Thus, define " first ", the feature of " second " can express or
Implicitly include one or more this feature.In describing the invention, " multiple " are meant that two or more, unless separately
There is clearly specific restriction.
In the present invention, unless otherwise clearly defined and limited, term " installation ", " connected ", " connection ", " fixation " etc.
Term should be interpreted broadly, for example, it may be fixedly connected, or be detachably connected, or it is integral；Can be that machinery connects
Connect, or electrically connect；Can be joined directly together, it is also possible to be indirectly connected to by intermediary, can be in two elements
The connection in portion or the interaction relationship of two elements.For the ordinary skill in the art, can be according to concrete feelings
Condition understands above-mentioned term concrete meaning in the present invention.
In the present invention, unless otherwise clearly defined and limited, fisrt feature second feature " on " or D score can be with
It is the first and second feature directly contacts, or the first and second features are by intermediary mediate contact.And, fisrt feature exists
Second feature " on ", " top " and " above " but fisrt feature are directly over second feature or oblique upper, or be merely representative of
Fisrt feature level height is higher than second feature.Fisrt feature second feature " under ", " lower section " and " below " can be
One feature is immediately below second feature or obliquely downward, or is merely representative of fisrt feature level height less than second feature.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show
The description of example " or " some examples " etc. means to combine specific features, structure, material or spy that the embodiment or example are described
Point is contained at least one embodiment of the present invention or example.In this manual, to the schematic representation of above-mentioned term not
Identical embodiment or example must be directed to.And, the specific features of description, structure, material or feature can be with office
Combine in an appropriate manner in one or more embodiments or example.Additionally, in the case of not conflicting, the skill of this area
Art personnel can be tied the feature of the different embodiments or example described in this specification and different embodiments or example
Close and combine.
Although embodiments of the invention have been shown and described above, it is to be understood that above-described embodiment is example
Property, it is impossible to limitation of the present invention is interpreted as, one of ordinary skill in the art within the scope of the invention can be to above-mentioned
Embodiment is changed, changes, replacing and modification.
Claims (7)
1. a kind of artificial bone structure with density gradient, it is characterised in that include the artificial bone body with preset shape and
The some suckings being opened on the artificial bone body, the first linkage section of the artificial bone body and required absorption rate compared with
High side knochenbruch is connected and is absorbed by the side knochenbruch, its second linkage section side knochenbruch phase relatively low with required absorption rate
Even and by the side knochenbruch absorb；The density of the sucking on first linkage section is more than on second linkage section
The density of the sucking, the artificial bone body is mixture of calcium sulfate or calcium phosphate mixture；On the artificial bone body
Sucking density it is proportional with the required absorption rate at this, the aperture of the sucking on the artificial bone body with this at
Required absorption rate be directly proportional.
2. the artificial bone structure with density gradient according to claim 1, it is characterised in that positioned at the described first connection
Aperture of the aperture of the sucking in section more than the sucking on second linkage section.
3. the artificial bone structure with density gradient according to claim 2, it is characterised in that positioned at the described first connection
The aperture of the aperture of the sucking in section and the sucking on second linkage section between 100 microns -400 microns with
The formal distribution of bore diameter gradient.
4. the artificial bone structure with density gradient according to claim 1, it is characterised in that positioned at the described first connection
The density of the density of the sucking in section and the sucking on second linkage section is between 0-200 every square centimeter
With the formal distribution of density gradient.
5. the artificial bone structure with density gradient according to claim 4, it is characterised in that on same linkage section
Multiple described sucking be distributed in the artificial bone body.
6. the artificial bone structure with density gradient according to claim 1, it is characterised in that first linkage section is
Mixture of calcium sulfate, second linkage section is calcium phosphate mixture.
7. the artificial bone structure with density gradient according to claim 6, it is characterised in that the preset shape is wedge
Shape, rectangle, disk or sphere.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611035833.7A CN106620882A (en) | 2016-11-18 | 2016-11-18 | Artificial bone structure having density gradient |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611035833.7A CN106620882A (en) | 2016-11-18 | 2016-11-18 | Artificial bone structure having density gradient |
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| Publication Number | Publication Date |
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| CN106620882A true CN106620882A (en) | 2017-05-10 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201611035833.7A Pending CN106620882A (en) | 2016-11-18 | 2016-11-18 | Artificial bone structure having density gradient |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109172044A (en) * | 2018-07-24 | 2019-01-11 | 西安交通大学 | A kind of degradable gradient-porosity mammary gland bracket |
| CN110584838A (en) * | 2019-09-12 | 2019-12-20 | 北京爱康宜诚医疗器材有限公司 | Acetabular prosthesis |
| CN112386345A (en) * | 2020-11-13 | 2021-02-23 | 苏州诺普再生医学有限公司 | Alveolar bone increment support system |
| CN113041396A (en) * | 2021-03-08 | 2021-06-29 | 四川大学 | Preparation method of bracket material with gap gradient structure |
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| CN113041396B (en) * | 2021-03-08 | 2021-11-30 | 四川大学 | Preparation method of bracket material with gap gradient structure |
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