CN106618477A - Portable non-mydriatic fundus imaging device - Google Patents
Portable non-mydriatic fundus imaging device Download PDFInfo
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- CN106618477A CN106618477A CN201611260253.8A CN201611260253A CN106618477A CN 106618477 A CN106618477 A CN 106618477A CN 201611260253 A CN201611260253 A CN 201611260253A CN 106618477 A CN106618477 A CN 106618477A
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- light
- imaging
- relay lens
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- light source
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/0008—Apparatus for testing the eyes; Instruments for examining the eyes provided with illuminating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/0016—Operational features thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/14—Arrangements specially adapted for eye photography
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Eye Examination Apparatus (AREA)
Abstract
The invention provides a portable non-mydriatic fundus imaging device. The device comprises an eyepiece and a relay lens assembly which are sequentially arranged in front of a to-be-tested eye, and the eyepiece is located between the to-be-tested eye and the relay lens assembly. An imaging polarizer is arranged on the imaging light-in side of the relay lens assembly and between the eyepiece and the relay lens assembly. An image sensor assembly is arranged on the imaging light-out side of the relay lens assembly. The eyepiece, the imaging polarizer, the relay lens assembly and the image sensor assembly are coaxially arranged. An illumination assembly is transversely arranged on one side of an optical axis in a deviated mode. The device has the advantages that under the condition that the to-be-tested eye is subjected to mydriasis without medicine, the to-be-tested eye can be observed in real time and subjected to video recording and flash photography. The device is mainly characterized in that high-definition imaging of the fundus of the to-be-tested eye is achieved by means of stray light, the host image subduction technology and the aberration correction technology on the premise that portability is maintained.
Description
Technical field
It is particularly a kind of portable to exempt from the present invention relates to a kind of imaging device, belongs to Medical Instruments microscopy field
Mydriasis fundus imaging equipment.
Background technology
Fundus camera is a kind of traditional armarium, for observing, recording human eye retina's image, be doctor analysis and
Diagnosis provides objective basis.The blood capillary that uniquely can be observed directly in human body is dispersed with the retina that fundus camera is detected
Pipe, the change of these Microvascular architectures can be used for the early diagnosiss of various diseases such as fundus oculi disease, hypertension, diabetes, into
For the important means of modern medical service diagnosis.In the world the desk-top fundus camera of First by German CARLZEISS companies in 1925
Year is trial-produceed successfully, and subsequently, design of CANON, TOPCON, NIKON, OLYMPUS, OPTON Deng Duo companies to fundus camera is entered
Substantial amounts of improvement is gone, now desktop computer on the market can realize all automatic measurement with one-key start.
However, desk-top fundus camera is more comprising more complicated imaging, illumination, Pupil diameter, focusing instruction, fixation lamp etc.
Bar light path, or even also include the light paths such as outer eye light, external eyes observation, the focusing of external eyes fixation, external eyes, thus structure is more complicated,
Volume is big and heavy, while facing higher Costco Wholesale and cost of transportation.Additionally, facing laid-up patient, doctor
Go to the countryside examination and follow-up, particularly to the examination and follow-up of outlying district patient, portable mydriasis of exempting from just shows with fundus camera
Obtain particularly important.Chinese patent " hand-held ophthalmoscope " early in Patent No. 92105247.2 in 1994 discloses one
Plant hand-held ophthalmofundoscope.Hereafter, in terms of each key technology of Portable fundus camera substantial amounts of research has been made both at home and abroad.
Prior art, United States Patent (USP)《DIGITAL DOCUMENTING OPHTHALMOSCOPE》(the patent No.：
US7364297B2 a kind of wide-angle ophthalmoscope) is disclosed, can be visually observed, it is also possible to which connecting with external mobile phone preserves image, and the angle of visual field can
With to 25 degree.But it does not provide infrared preview function, but using white light long-time direct irradiation patient's eyes bottom, to patient
Discomfort, and coverage is caused to meet simultaneously it was observed that optic disc and macula lutea.
Prior art, United States Patent (USP)《MEDICAL IMAGING SYSTEM》(the patent No.：US8988518B2 one) is disclosed
Hand-held fundus camera is planted, is shone directly into using infrared and white light LEDs and is connect mesh object lens, realize the off-axis photograph to eye to be checked
Bright, optical fundus Jing connects mesh object lens and imaging optical path images in photoelectric sensor, and is the signal of telecommunication by conversion of photoelectric sensor, so as to reality
Now to the record of eye fundus image.In the program, infrared LED for infrared preview illumination, because eye to be checked it is insensitive to infrared light, in advance
Oculopupillary diminution to be checked will not be caused when looking at, namely realize taking pictures the mydriasis of exempting from of eye to be checked.
Prior art, Chinese invention patent《A kind of Portable fundus camera》(application number：201410619382.6)
Disclose a kind of hand-held fundus camera, its basic structure and implementation and Chinese invention patent《Lens module and optical fundus
Camera》(application number：201310756402.X) similar, Main Differences are that the version of imaging len is different.
Prior art, United States Patent (USP)《EXAMINATION INSTRUMENT》(the patent No.：US9033507B2 one) is disclosed
Hand-held fundus camera is planted, infrared and white light LEDs outgoing beam is coupled to by spectroscope is connect mesh object lens, realized to be checked
The off-axis illumination of eye, optical fundus Jing connects mesh object lens and imaging optical path images in two-dimension photoelectric sensor, and by conversion of photoelectric sensor
For the signal of telecommunication, so as to realize the record to eye fundus image.Meanwhile, inserting spectroscope after mesh object lens are connect is used for leading for fixation lamp
Enter, by the position for changing fixation lamp, the image of optical fundus different parts can be obtained.
The content of the invention
For defect of the prior art, it is an object of the invention to provide on the premise of a kind of holding portability, using miscellaneous
Astigmatism, ghost image abatement technology and aberration correction technology realize being imaged the high definition on eye optical fundus to be checked it is portable exempt from mydriasis optical fundus into
As equipment.
To solve above-mentioned technical problem, a kind of portable of present invention offer exempts from mydriasis fundus imaging equipment, including：Connect mesh
Object lens and relay lens assemblies, it is described to connect mesh object lens and the relay lens assemblies are successively set on the front of eyes to be checked, institute
State and connect mesh object lens positioned between the eyes to be checked and the relay lens assemblies；Imaging polarization piece, the imaging polarization piece sets
Put the imaging light in the relay lens assemblies and inject side, the imaging polarization piece is located at the mesh object lens that connect with the relaying
Between lens subassembly；Image sensor module, described image sensor component is arranged on the imaging of the relay lens assemblies
Line emitting side；It is wherein described to connect mesh object lens, the imaging polarization piece, the relay lens assemblies and described image sensor component
It is coaxially disposed, the line at the center for connecing mesh object lens, the imaging polarization piece and the relay lens assemblies forms optical axis；According to
Bright component, the light fixture lateral run-out is arranged on the side of the optical axis.
Preferably, the beam projecting normal plane of the light fixture and the angle of the optical axis are 10 degree～50 degree.
Preferably, the beam projecting normal plane of the light fixture and the angle of the optical axis are 30 degree.
Preferably, the light fixture includes light source cell and the photograph being arranged on the illumination path of the light source cell
Bright polaroid.
Preferably, focus lamp is provided with the illumination path of the light source cell, the focus lamp is located at the light source list
Between the first and polarization of illumination piece.
Preferably, spatial filter is provided with the illumination path of the light source cell, the spatial filter is arranged on
On the convergent point of the focus lamp.
Preferably, polarization of illumination piece setting orthogonal with the imaging polarization piece.
Preferably, the light source cell is single light source or multiple light courcess, and the light source cell is infrared illumination source or white light
Lighting source.
Preferably, it is described to connect mesh object lens for single element lens or multi-disc lens combination.
Preferably, the relay lens assemblies are multi-disc lens combination.
Compared with prior art, beneficial effects of the present invention are as follows：So that be detected eye is carrying out mydriasis without medicine
In the case of, Real Time Observation, video recording and flash photographing just can be carried out to tested eye.It is mainly characterized by the premise for keeping portability
Under, realize that the high definition to eye optical fundus to be checked is imaged using veiling glare, ghost image abatement technology and aberration correction technology.
Description of the drawings
By reading the detailed description made to non-limiting example with reference to the following drawings, the further feature mesh of the present invention
And advantage will become more apparent upon.
Fig. 1 exempts from the light path configuration figure of mydriasis fundus imaging apparatus embodiments one for the present invention is portable；
Fig. 2A is prior art fundus illumination design sketch；
Fig. 2 B are the portable fundus illumination design sketch for exempting from mydriasis fundus imaging equipment of the present invention；
Fig. 3 exempts from mydriasis fundus imaging equipment source layout figure for the present invention is portable；
Fig. 4 is the portable clear aperature point exempted from mydriasis fundus imaging equipment light source lighting and be imaged at pupil of the present invention
Butut；
Fig. 5 exempts from the light path configuration figure of mydriasis fundus imaging apparatus embodiments two for the present invention is portable.
In figure：
1- eyes 2- to be checked connect mesh object lens 3- relay lens assemblies
4- image sensor module 5- light source cell 6- polarization of illumination pieces
7- imaging polarization piece 11- optical fundus 12- pupils
13- plane 14- optical axis 21- light sources
22- imagings aperture 31- illuminating bundle roundlets 32- imaging roundlets
33- pupils edge 34- pupil center hole 41- focus lamps
42- convergent points
Specific embodiment
With reference to specific embodiment, the present invention is described in detail.Following examples will be helpful to the technology of this area
Personnel further understand the present invention, but the invention is not limited in any way.It should be pointed out that the ordinary skill to this area
For personnel, without departing from the inventive concept of the premise, some changes and improvements can also be made.These belong to the present invention
Protection domain.
The present invention includes the infrared illumination source for optical fundus black and white preview, the white light stroboscopic light sources that optical fundus color picture shoots,
What illuminator and imaging system were shared connects mesh objective lens unit, will connect mesh object lens and opthalmic optics' system to optical fundus institute into once in fact
As carrying out the relay lens assemblies of secondary imaging, and secondary picture is converted into into the two-dimensional image sensor of the signal of telecommunication.
As shown in figure 1, the present invention is portable to exempt from mydriasis fundus imaging equipment, with the infrared illumination that optical axis 14 has lateral run-out
The infrared or white light beam warp polarization of illumination piece 6 that light source or white-light illuminating light source cell 5 send shines and connects mesh object lens 2, Jing
Connect the linearly polarized light beam after mesh object lens 2 to focus near the pupil 12 of eye to be checked, then Jing crystal of human eye projects optical fundus 11, so as to
Realize the illumination to human eye optical fundus 11.Reflection or the scattered light of optical fundus generation are illuminated by aforementioned polarized beam, a portion will
Sequentially pass through the vitreous body of eyes to be checked 1, crystal, anterior chamber and shone by anterior surface of cornea and connect on mesh object lens 2.This part is by connecing
The fundus reflex or scattered beam of the outgoing of mesh object lens 2 will be imaged in the rear side plane 13 for connecing mesh object lens, and this is eye eye to be checked
Bottom once as.This is once as the imaging polarization pieces 7, relay lens assemblies 3 orthogonally located with polarization of illumination piece 6 of Jing again is imaged in
Two-dimensional image sensor component 4, so as to obtain the eye fundus image of eyes to be checked 1.When system works, infrared light is worked in first pre-
Look at pattern, because human eye is insensitive to infrared light, pupil 12 will not be caused to shrink；After aiming at and preparation of focusing is ready,
System start-up white light flash mode, obtains the coloured image on the optical fundus of eyes 1 to be checked, that is, realize the optical fundus to eyes to be checked 1
Exempt from mydriasis imaging.
For the eyes to be checked 1 of different refractive status, in order to obtain clearly image, it is necessary to carry out dioptric benefit to eye to be checked
Repay.This by being individually moved relay lens assemblies 3, or can be individually moved two-dimensional image sensor component 4, or same time shift
Dynamic relay lens assemblies 3 and two-dimensional image sensor component 4 are realized.
In order to obtain clearly eye fundus image, mesh object lens 2 are connect with positive angular, can be saturating using single element lens or multi-disc
Microscope group is closed, and relay lens assemblies 3 adopt multi-disc lens combination.In order to reduce the veiling glare and ghost image of system, using as previously mentioned
Orthogonally located polarization of illumination piece 6 and imaging polarization piece 7, to cut down the veiling glare of the cornea of eyes to be checked 1 and crystal reflection.
The beam projecting normal plane of light source cell of the present invention 5 has certain angle with optical axis 14, and scope is 10 degree～50 degree, allusion quotation
Offset is 30 degree.The illumination that can realize evenly on the optical fundus 11 of eyes to be checked 1 is arranged so as to, so that system obtains eye
There is the photo of bottom 11 more preferable relative illumination to be distributed.In order to illustrate that the normal of light source cell 5 has the light at inclination angle relative to optical axis 14
The advantage of source arrangement, Fig. 2A and Fig. 2 B give light source cell 5 when being 30 degree without inclination angle and inclination angle relative to optical axis
The illumination uniformity numerical simulation comparison diagram of optical fundus 11.It can be seen that when light source cell 5 is relative to inclined light shaft angle
When 30 degree, it is possible to obtain the illumination uniformity of more preferable optical fundus 11, namely can obtain when carrying out 11 image taking of optical fundus preferably
Picture uniformity.
The situation of the single source 21 that there is inclination angle placement with optical axis 14 is only show in Fig. 1, in practice, it is therefore possible to use two
It is individual even more than light source 21, referring to Fig. 3, wherein 21 be light source, 22 for imaging aperture.Left figure shows that in the vertical direction is placed
The situation of two light sources 21, right figure is the situation of single source 21.
In order to the image of optical fundus 11 that the present invention such as how more succinct mode obtains eyes to be checked 1 is better described, we
Also the light footprint figure of illuminating bundle and imaging beam at pupil is provided, referring to Fig. 4.Pupil edge 33 is given by greatest circle in figure
Go out, imaging optical path passes through illuminating bundle roundlet 31 by being imaged roundlet 32, illumination path.Wherein left figure corresponds to two illumination light
The situation in source, illuminating bundle is by upper and lower two illuminating bundle roundlets 31, and imaging beam passes through pupil center hole 34.Right figure
For the situation of single source illumination, illuminating bundle is by illuminating bundle roundlet 31, and imaging beam passes through to be imaged roundlet 32, for
Same illuminating bundle aperture and imaging beam aperture, it is possible to achieve the shooting to the eye optical fundus to be checked of more microcoria.
An alternative embodiment of the invention is referring to Fig. 5.With main difference is that for previous embodiment：Light source cell 5
The light for going out line focus mirror 41 first converges at convergent point 42, then Jing illumination polaroids 6, connects mesh object lens 2 and converge at eyes to be checked 1
Pupil 12 at.Now such as a spatial filter (not shown) is placed in convergent point 42, be beneficial to control pupil 12
The size of place's illumination spot, to reduce the veiling glare of original system.
The specific embodiment of the present invention is described above.It is to be appreciated that the invention is not limited in above-mentioned
Particular implementation, those skilled in the art can within the scope of the claims make a variety of changes or change, this not shadow
Ring the flesh and blood of the present invention.In the case where not conflicting, the feature in embodiments herein and embodiment can any phase
Mutually combination.
Claims (10)
1. one kind is portable exempts from mydriasis fundus imaging equipment, it is characterised in that include：
Connect mesh object lens and relay lens assemblies, it is described to connect mesh object lens and the relay lens assemblies are successively set on eyes to be checked
Front, the mesh object lens that connect are located between the eyes to be checked and the relay lens assemblies；
Imaging polarization piece, the imaging polarization piece is arranged on the imaging light of the relay lens assemblies and injects side, the imaging
Polaroid is located at described connecing between mesh object lens and the relay lens assemblies；
Image sensor module, described image sensor component is arranged on the imaging light exiting side of the relay lens assemblies；
Wherein
Mesh object lens, the imaging polarization piece, the relay lens assemblies and the described image sensor component of connecing is coaxially disposed,
The line at the center for connecing mesh object lens, the imaging polarization piece and the relay lens assemblies forms optical axis；
Light fixture, the light fixture lateral run-out is arranged on the side of the optical axis.
2. it is according to claim 1 portable to exempt from mydriasis fundus imaging equipment, it is characterised in that the light of the light fixture
Line outgoing normal plane is 10 degree～50 degree with the angle of the optical axis.
3. it is according to claim 2 portable to exempt from mydriasis fundus imaging equipment, it is characterised in that the light of the light fixture
Line outgoing normal plane is 30 degree with the angle of the optical axis.
4. it is according to claim 1 portable to exempt from mydriasis fundus imaging equipment, it is characterised in that the light fixture includes
Light source cell and the polarization of illumination piece being arranged on the illumination path of the light source cell.
5. it is according to claim 4 portable to exempt from mydriasis fundus imaging equipment, it is characterised in that in the light source cell
Illumination path is provided with focus lamp, and the focus lamp is located between the light source cell and the polarization of illumination piece.
6. it is according to claim 5 portable to exempt from mydriasis fundus imaging equipment, it is characterised in that in the light source cell
Illumination path is provided with spatial filter, and the spatial filter is arranged on the convergent point of the focus lamp.
7. portable according to claim 4 or 5 exempts from mydriasis fundus imaging equipment, it is characterised in that the polarization of illumination
Piece setting orthogonal with the imaging polarization piece.
8. it is according to claim 4 portable to exempt from mydriasis fundus imaging equipment, it is characterised in that the light source cell is single
Light source or multiple light courcess, the light source cell is infrared illumination source or white-light illuminating light source.
9. it is according to claim 1 portable to exempt from mydriasis fundus imaging equipment, it is characterised in that described to connect mesh object lens for single
Piece lens or multi-disc lens combination.
10. it is according to claim 1 portable to exempt from mydriasis fundus imaging equipment, it is characterised in that the relay lens group
Part is multi-disc lens combination.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611260253.8A CN106618477A (en) | 2016-12-30 | 2016-12-30 | Portable non-mydriatic fundus imaging device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611260253.8A CN106618477A (en) | 2016-12-30 | 2016-12-30 | Portable non-mydriatic fundus imaging device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106618477A true CN106618477A (en) | 2017-05-10 |
Family
ID=58838065
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611260253.8A Pending CN106618477A (en) | 2016-12-30 | 2016-12-30 | Portable non-mydriatic fundus imaging device |
Country Status (1)
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109893087A (en) * | 2019-04-11 | 2019-06-18 | 北京悦琦创通科技有限公司 | A kind of hand-held fundus camera |
| CN110074753A (en) * | 2019-04-26 | 2019-08-02 | 北京至真互联网技术有限公司 | Fundus camera |
| CN112006650A (en) * | 2020-09-21 | 2020-12-01 | 南京览视医疗科技有限公司 | Method for collecting fundus image and fundus camera |
| CN112790895A (en) * | 2020-12-28 | 2021-05-14 | 上海美沃精密仪器股份有限公司 | Artificial crystal compensation correction system and method |
| WO2022090817A1 (en) * | 2020-11-02 | 2022-05-05 | C-Mer Rainsoptics Limited | Adaptor and method for capturing images of a retina of an eye |
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Application publication date: 20170510 |