CN106581870A - Purpose of light-message-transmission-medium energy enablement lamp serving as treatment device for myocardial ischemia - Google Patents

Purpose of light-message-transmission-medium energy enablement lamp serving as treatment device for myocardial ischemia Download PDF

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Publication number
CN106581870A
CN106581870A CN201710124505.2A CN201710124505A CN106581870A CN 106581870 A CN106581870 A CN 106581870A CN 201710124505 A CN201710124505 A CN 201710124505A CN 106581870 A CN106581870 A CN 106581870A
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myocardial ischemia
cabinet
metal alloy
panel
carbon pipe
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CN201710124505.2A
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Chinese (zh)
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陈美光
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Priority to CN201710124505.2A priority Critical patent/CN106581870A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/005Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/05General characteristics of the apparatus combined with other kinds of therapy
    • A61M2205/051General characteristics of the apparatus combined with other kinds of therapy with radiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/05General characteristics of the apparatus combined with other kinds of therapy
    • A61M2205/051General characteristics of the apparatus combined with other kinds of therapy with radiation therapy
    • A61M2205/052General characteristics of the apparatus combined with other kinds of therapy with radiation therapy infrared
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0632Constructional aspects of the apparatus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/065Light sources therefor
    • A61N2005/0655Tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659Radiation therapy using light characterised by the wavelength of light used infrared
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662Visible light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0664Details

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a purpose of a light-message-transmission-medium energy enablement lamp in preparing a device for preventing and/or treating myocardial ischemia. The light-message-transmission-medium energy enablement lamp has an exact treatment and myocardial ischemia prevention effect, provides a new selection for treatment of clinical cardiovascular diseases and has a wide clinical application and market prospect.

Description

Light news opens energy lamp as the purposes of the therapeutic system of myocardial ischemia
Technical field
The present invention relates to a kind of device for treating myocardial ischemia.
Background technology
Myocardial ischemia refers to that the blood perfusion of heart is reduced, and the oxygen supply for causing heart is reduced, and energy metabolism of myocardial is abnormal, A kind of disease of normal heart action can not be supported.Coronary stenosis or obturation are to cause cardiac muscle caused by coronary atherosclerosis Ischemic is main, the modal cause of disease, and then causes myocardial ischemia-anoxemia, i.e., " coronary heart disease ".In coronary heart disease, in ischemic Wind, acute myocardial infarction, Buerger's disease, diabetes and wound etc. make erythrocyte aggregation increase and make WBV Raise.
At present, drug therapy is one of common treatment method of myocardial ischemia disease.
Existing document report shows that infrared ray combined atomizing treatment method has uniqueness in the treatment of angiocardiopathy Advantage.Compare with drug therapy, physical treatment incorporates the good effect of Chinese medicine, activity is strong, the features such as toxic and side effect is few, increasingly By the concern and application of vast cardiovascular patient.
The content of the invention
In order to solve the above problems, the invention provides a kind of device of new treatment myocardial ischemia.
The invention provides open can purposes of the lamp in the device for preparing prevention and/or treating myocardial ischemia.
Wherein, described device is the device for preventing and/or treating acute myocardial ischemia.
Wherein, described device is to shorten the device of duration of myocardial ischemia.
Wherein, the energy lamp that opens includes that superoxide anion O can be produced2 -Broad band full spectrum frequency spectrograph and ultrasonic humidifying Device;The broad band full spectrum frequency spectrograph from top to bottom includes cabinet, support and the base of earth-free outer shielding structure;The modeling Metal alloy plate, quartzy carbon pipe are provided with material casing;The quartzy carbon pipe is used to radiate having for 500nm~2.5 μm frequency spectrum Beneficial visible ray and near, mid-infrared light;The metal alloy plate absorbs infrared from 500nm~2.5 mum wavelength of quartzy carbon pipe, It is infrared that 2.5 μm~25 mum wavelengths are radiated simultaneously;The support is used for supporting plastic casing and connection cabinet and base;It is described Metal alloy plate top is composed in series by least 10 quartzy carbon pipes;The ultrasonic humidifier is located at broad band full and composes frequency spectrograph It is used to produce a large amount of water smokes and human body between, the light quantum generation effect that water smoke need to send with frequency spectrograph, water smoke is in frequency spectrograph face The optimum distance disappeared before plate for ultrasonic humidifier and frequency spectrograph.
Preferably, the front of the cabinet is provided with machine shell panel, and machine shell panel is provided with panel guard;The plastics Micro- shape fan, metal air chamber, metal alloy plate, quartzy carbon pipe are respectively equipped with casing by rear to front;The cabinet it is upper, Under be respectively provided with double louvres, this pair of louvre is used to guaranteeing that extraneous air is entered under the twitch of micro- shape fan being fixed on cabinet On metal air chamber;Metal air chamber surrounding lower section is equipped with air admission hole, for guaranteeing air via 2.5 μm~25 mum wavelengths of radiation Infrared metal alloy plate surface space electronic cloud, absorption negative electrical charge forms superoxide anion, and Jing panel guards are communicated to air In.
It is further preferred that the metal alloy plate top is composed in series by least 10 quartzy carbon pipes;The casing Panel is provided with power switch and quartzy carbon pipe switch;Automatic line receiver, spooler jump ring are set in the base, and is used for The anti-dumping switch automatically powered off when base inclines more than 15 degree of angles.
It is of the present invention to open energy lamp, energy lamp is opened also known as light news, purchased from Shanghai Qiangli Optoelectronic Technology Co., Ltd., product type Number:GXZ5A, product standard:Q/SWLB 01-2014, its structure is recorded in the patent that Authorization Notice No. is the B of CN 102451524 In application, specifically, is seen【0022】~【0040】It is shown.
The present invention opens energy light fixture definite treatment and prevention myocardial ischemia, is the treatment of clinical cardiovascular disease There is provided a kind of new selection, with wide clinical practice and market prospects.
Obviously, the above of the invention, according to the ordinary technical knowledge and customary means of this area, without departing from Under the premise of the above-mentioned basic fundamental thought of the present invention, the modification of other various ways can also be made, is replaced or is changed.
By the following examples the specific embodiment of form, remakes further specifically to the above of the present invention It is bright.But this scope for being interpreted as above-mentioned theme of the invention should not be only limitted to Examples below.It is all based on the above of the present invention The technology realized belongs to the scope of the present invention.
Description of the drawings
Fig. 1 is opened can impact of the lamp to rats with myocardial ischemia body weight.Note:7th day rat body weight, compares with control group, * P < 0.05。
Fig. 2 opens energy lamp to the Electrocardiographic impact of rats with myocardial ischemia.(A) Electrocardiographic situation of change before and after rat ischemia; (B) after pituitrin injection, there is the time of ischemic and recovery in rat.Note:Compare with control group, * P < 0.05;With compare Group compares , &P < 0.05.
Specific embodiment
The present invention of embodiment 1 treats myocardial ischemia using energy lamp is opened
1 material
1.1 animal used as test
From SPF levels Spahue-Dawlay (SD) rat, male, 160 ± 5g of body weight, by Shanghai Si Laike animals used as test Center provides (credit number:SCXK (Shanghai) 2007-0005).Put Fujian University of Traditional Chinese Medicine's Experimental Animal Center SPF level laboratory In normally feed, constant temperature, constant humidity, 12h illumination/day, adaptability feed 1 week after, carry out follow-up test.
1.2 Experimental agents and main agents
Pituitrin parenteral solution (the second hormone of Ningbo of Zhejiang factory);(Solution on Chemical Reagents in Shanghai import is public for yellow Jackets Department);Heparin sodium injection (Jiangsu Wanbang Biological Pharmaceutical Co., Ltd.).
1.3 experiment key instruments
Energy lamp is opened, also known as light news energy lamp, purchased from Shanghai Qiangli Optoelectronic Technology Co., Ltd., its model product type are opened Number:GXZ5A, product standard:Q/SWLB 01-2014, its structure is recorded in the patent that Authorization Notice No. is the B of CN 102451524 In application, specifically, is seen【0022】~【0040】It is shown.
Electronic balance scale (Shanghai Ao Haosi Instrument Ltd.);Biological functional system BL-420S (Chengdu Tai Meng sections Skill Co., Ltd);LBY-N6B Full-automatic self-cleaning blood rheological instruments (Pulisheng Instruments Co., Ltd., Beijing).
2 experimental techniques
2.1 rats are grouped
Healthy SPF levels SD male rat 20,160 ± 5g of body weight is placed in SPF levels laboratory and raises, freely activity, from By feed, drinking-water, ventilation, illumination is sufficient, and room temperature is controlled in (25 ± 1) DEG C, relative humidity 70%-80%.Adaptability is raised 3 days After tested.2 groups, i.e. control group are randomly divided into using random digits table by body weight, intervention group (opens energy lamp treatment group), often Group 10.
2.2 open can light irradiation method
After energy lamp and atomizer preheating 10min will be opened before intervention, device to be atomized has uniform water smoke ejection to be preferred, and rat is put In the carton of surrounding perforate ventilation, and supplements and water, adjustment lampshade is highly 30cm, intervenes 30min, once a day, It is continuous to intervene 7 days.
The weighing of 2.3 rat body weights
Rat is grouped at random by body weight, after the 1st intervention is carried out to intervention group, the body before intervening every other day to rat Weighed again again, i.e., weighed and recorded rat body weight within the 1st, 3,5 and the 7th days.
The foundation of 2.4 Model Rats with Acute Myocardial Ischemia
The yellow Jackets (40mg/ml) of 7th the Heavenly Stems prognosis 1h lumbar injections 1% anaesthetize, treat rat lie down, human body it is soft, After showing anesthesia success, rats by intraperitoneal injection pituitrin (Pit), is injected by 0.5U/kg after 10min, and is noted in 5s Shoot away complete.The ECG Change of rat in 3min is recorded after injection, S-T segment raises >=and 0.1mv is modeling success.
2.5 Rat Ecgs are detected
After injection of pituitrin, record rat occur myocardial ischemia experience time and from ischemic to recover when experience Time, compare the time difference between intervention group and control group.
2.6 statistical analysis
Experimental data is with mean+SDRepresent, with the software analysis of SPSS 18, compare between multigroup mean Checked using one-way analysis of variance, P<0.05 be considered as it is statistically significant.
3 results
The weighing observation of 3.1 rat body weights
1st, 3,5 days, there was no significant difference for intervention group and the rat body weight for compareing, and has in the body weight of the 7th day two groups of rats Difference (such as Fig. 1).
3.2 open energy lamp to the Electrocardiographic impact of the rats with myocardial ischemia that pituitrin is mediated
In the Electrocardiographic waveform of normal rat, T ripples are towering, and after injection of pituitrin, rat cardiac muscle occurs and lacks After blood, there is the low flat or even inverted phenomenon of T ripples, after rest, presentation is gradually brought to that the trend (figure of front T wave heights is administered 2A)。
Intervention group (Fig. 2 B) compared with control group, after injection of pituitrin, intervention group rat occur myocardial ischemia when Between be 53.35 ± 15.12s, and control group occur myocardial ischemia time be 23.2 ± 28.71s;Occur continuing after myocardial ischemia Two groups of recovery situation is observed, is as a result found, the time that intervention group is recovered is 54 ± 25.54s, and the recovery time of control group is then 96.7 ± 37.53s is needed, significant difference is respectively provided with, illustrates to open the rat heart muscle that energy lamp can delay pituitrin to cause Ischemic, while the recovery of ischemic myocardium can be promoted, reaches the effect of Ischemic myocardium damage.
4 conclusions
Acute Myocardial Ischemia in Rats experiment caused by pituitrin is to study that one of medicaments for resisting myocardial ischemia important and Jing The animal model of allusion quotation.Acute myocardial ischemia damages cardiac muscle, while with the appearance of abnormal electrocardiographic pattern.ECG ST section, T Ripple is to react the relatively reliable index of Myocardial injury degree extremely.
The present invention promotes the recovery of ischemic myocardium by suppressing raising for rats with myocardial ischemia ST segment value, reaches the protection heart The effect of myocardial ischemia.
This result of study shows that open the myocardial ischemia in rats that energy lamp can delay pituitrin to cause, reduction cardiac muscle lacks Blood is damaged, and shortens the time of myocardial ischemia, illustrates that it has the effect of prevention and treatment myocardial ischemia.
To sum up, opening energy light fixture plays the role of definite treatment and prevention myocardial ischemia, is the treatment of clinical cardiovascular disease There is provided a kind of new selection, with wide clinical practice and market prospects.

Claims (6)

1. opening can purposes of the lamp in the device for preparing prevention and/or treating myocardial ischemia.
2. purposes according to claim 1, it is characterised in that:Described device is to prevent and/or treat acute myocardial ischemia Device.
3. purposes according to claim 1, it is characterised in that:Described device is to shorten the device of duration of myocardial ischemia.
4. the purposes according to claims 1 to 3 any one, it is characterised in that:The energy lamp that opens includes that super oxygen can be produced Anion O2 -Broad band full spectrum frequency spectrograph and ultrasonic humidifier;The broad band full spectrum frequency spectrograph from top to bottom includes earth-free The cabinet of outer shielding structure, support and base;Metal alloy plate, quartzy carbon pipe are provided with the cabinet;It is described Quartzy carbon pipe is used to radiate the beneficial visible ray of 500nm~2.5 μm frequency spectrum and near, mid-infrared light;The metal alloy plate is inhaled Receive infrared from 500nm~2.5 mum wavelength of quartzy carbon pipe, while it is infrared to radiate 2.5 μm~25 mum wavelengths;The support is used In supporting plastic casing and connection cabinet and base;The metal alloy plate top is by least 10 quartzy carbon pipe series connection Composition;The ultrasonic humidifier is located at broad band full and composes for producing a large amount of water smokes between frequency spectrograph and human body, and water smoke need to be with frequency Light quantum generation that spectrometer sends effect, water smoke disappears before frequency spectrograph panel be ultrasonic humidifier and frequency spectrograph it is optimal away from From.
5. purposes according to claim 4, it is characterised in that:The front of the cabinet is provided with machine shell panel, casing Panel is provided with panel guard;Micro- shape fan, metal air chamber, metal alloy are respectively equipped with the cabinet by rear to front Plate, quartzy carbon pipe;The cabinet it is upper, under be respectively provided with double louvres, this pair of louvre is used to guarantee extraneous air micro- Shape fan is twitched lower into the metal air chamber being fixed on cabinet;Metal air chamber surrounding lower section is equipped with air admission hole, is used for Air is guaranteed via the infrared metal alloy plate surface space electronic cloud of 2.5 μm~25 mum wavelengths of radiation, absorption negative electrical charge is formed Superoxide anion, Jing panel guards are communicated in air.
6. purposes according to claim 5, it is characterised in that:The metal alloy plate top is by least 10 quartzy carbons Pipe is composed in series;The machine shell panel is provided with power switch and quartzy carbon pipe switch;Automatic line receiver is set in the base, Spooler jump ring, and the anti-dumping switch for automatically powering off when base inclines more than 15 degree of angles.
CN201710124505.2A 2017-03-03 2017-03-03 Purpose of light-message-transmission-medium energy enablement lamp serving as treatment device for myocardial ischemia Pending CN106581870A (en)

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CN201710124505.2A CN106581870A (en) 2017-03-03 2017-03-03 Purpose of light-message-transmission-medium energy enablement lamp serving as treatment device for myocardial ischemia

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Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101122180A (en) * 2007-09-17 2008-02-13 张景和 Tourmaline health preserving room
CN101336785A (en) * 2008-08-13 2009-01-07 高洪祥 Far-infrared negative-ion magnetic health mattress
CN101496935A (en) * 2008-01-31 2009-08-05 易智强 Physiotherapy equipment with composite efficacy
CN102451524B (en) * 2011-06-29 2014-07-23 郑国贤 Physiotherapy instrument and use method thereof
TWI446933B (en) * 2012-12-17 2014-08-01 Jin Hong Chang Health maintenance material for use of preparing medicine for prevention and cure of cardiovascular diseases and health maintenance of biotechnology
CN204293698U (en) * 2014-11-26 2015-04-29 彭良玉 A kind of QI and blood bilateral negative oxygen ion health-care physiotherapeutic room
CN205054209U (en) * 2015-09-23 2016-03-02 冼添丽 Multi -functional healthy hand lace
CN205108775U (en) * 2015-11-13 2016-03-30 王宝光 Far infrared negative oxygen ion energy room
CN105617540A (en) * 2015-12-25 2016-06-01 南通生命多奇健康科技有限公司 Light supplementing health preserving instrument

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101122180A (en) * 2007-09-17 2008-02-13 张景和 Tourmaline health preserving room
CN101496935A (en) * 2008-01-31 2009-08-05 易智强 Physiotherapy equipment with composite efficacy
CN101336785A (en) * 2008-08-13 2009-01-07 高洪祥 Far-infrared negative-ion magnetic health mattress
CN102451524B (en) * 2011-06-29 2014-07-23 郑国贤 Physiotherapy instrument and use method thereof
TWI446933B (en) * 2012-12-17 2014-08-01 Jin Hong Chang Health maintenance material for use of preparing medicine for prevention and cure of cardiovascular diseases and health maintenance of biotechnology
CN204293698U (en) * 2014-11-26 2015-04-29 彭良玉 A kind of QI and blood bilateral negative oxygen ion health-care physiotherapeutic room
CN205054209U (en) * 2015-09-23 2016-03-02 冼添丽 Multi -functional healthy hand lace
CN205108775U (en) * 2015-11-13 2016-03-30 王宝光 Far infrared negative oxygen ion energy room
CN105617540A (en) * 2015-12-25 2016-06-01 南通生命多奇健康科技有限公司 Light supplementing health preserving instrument

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