CN106572858A - Devices, systems and methods for an oscillating crown drive for rotational atherectomy - Google Patents

Abstract

The present invention is directed in various methods, devices and systems relating to rotational atherectomy. More specifically, an oscillating driver is connected to a drive shaft, or torque transfer tube, with abrasive element mounted thereon. The result provides a rotational working diameter for the rotating abrasive element that is larger than its resting diameter. Generally, the preferred abrasive element is concentric in profile and/or with center of mass collinear with the drive shaft's rotational axis. However, eccentric abrasive elements, both in terms of offsetting center of mass and/or geometric eccentricity may also be employed.

Description

For the equipment of the vibration bizet driving of rotary-cut art, System and method for

Cross-Reference to Related Applications

The application be on March 13rd, 2014 submit to U.S. Patent application No.14/208,585 cip application, its will The U.S. Provisional Application No.61/782 that on March 14th, 2013 submits to, 184 rights and interests, what this applied is asked all to pass through what is quoted Mode is incorporated herein.

Technical field

The disclosure relates generally to the equipment and system with regard to rotary-cut art.More specifically, oscillatory driver is connected to which On the drive shaft of grinding head is installed.As a result it is that to provide rotary work more than its rest diameter for spin finishing element straight Footpath.

Background technology

Work out for removing or repairing multiple technologies and device in tremulous pulse with the tissue in similar body passage. This technology is to remove the atheromatous plaque in patient's tremulous pulse with the general object of device.Arteriosclerosis are characterised by Lipidosiss (atheroma) in the theca interna (subendothelial) of patient vessel.Process generally over time, initially Be deposited as relatively soft, the atheromatous hardened material rich in cholesterol into calcified atherosclerotic speckle.This tremulous pulse Gruel type limits the flowing of blood, and thus so-called for Stenotic pathologic change or restenosis, and barrier material is claimed For stenotic material.If do not processed, this is narrow to be likely to result in angina pectoriss, hypertension, myocardial infarction, apoplexy etc..

Rotary-cut program is had become for removing the usual technology of this stenotic material.This program is most frequently used for starting The opening of the arteriosteogenesiss pathological changes in coronary artery.Most generally rotary-cut program is not used alone, but follows with sacculus Plasty program, this is fairly frequently followed then with the opening of the tremulous pulse for arranging support to assist to stay open.For non-calcium For changing pathological changes, Balloon Angioplasty is most generally used alone to open tremulous pulse, and is to stay open generally by rack arrangement Artery open.However, research shows, experience Balloon Angioplasty and make the patient of rack arrangement significant proportion in the artery Undergo the obstruction of stent restenosis, i.e. support, this due in support scar tissue excessive growth during a period of time most Continually develop.In this case, rotary-cut art program is that from support, (Balloon Angioplasty is not by excessive scar tissue in support It is highly effective) preferable procedure that removes, thus recover the opening of tremulous pulse.

Have been developed over for attempting to remove several rotating-cutting equipments of stenotic material.In a kind of equipment, such as in the U.S. Patent No.4, illustrates in 990,134 (certifications), performs the grinding by such as diamond grains in the far-end of flexible drive shaft Property grinding-material cover brill.When bore across narrow advance when, its rotate at high speed (normally, for example about 150, In the range of 000-190,000rpm).However, as stenotic tissue is removed by this brill, therefore which stops blood flow.Once bore Narrow advance is had passed over, tremulous pulse will be opened to equal to or be only slightly greater than the diameter of the maximum outside diameter for boring.Normally, The brill of more than one size must be utilized so that tremulous pulse is opened to desired diameter.

United States Patent (USP) No.5,314,438 (Shturman) disclose another kind of rotating-cutting equipment, and which has drive shaft, drive A part for axle has the diameter for expanding, and at least a portion of enlarged surface is coated with grinding-material to limit the grinding of drive shaft Part.When rotated at high speed, stenotic tissue can be removed by means of abrasion from tremulous pulse.Although this rotating-cutting equipment is flexible due to which With some advantages more than Auth equipment, but as this equipment is actually uninfluenced, therefore which can also only open dynamic Diameter of the arteries and veins to the diameter of the expansion lapped face of approximately equal to drive shaft.

United States Patent (USP) No.6,494,890 (thanking to Germania) is disclosed with known to the drive shaft with amplification eccentric part Rotating-cutting equipment, at least a portion of wherein this amplifier section is covered with grinding-material.When rotated at high speed, means of abrasion Stenotic tissue can be removed from tremulous pulse.This equipment can open tremulous pulse to the straight of the rest diameter more than the eccentric part for expanding Footpath, partially due to the orbital rotational motion during high speed operation.As the eccentric part for expanding includes not being held together Driving axis, therefore during being arranged in narrow or during high speed operation, the expansion of drive shaft Eccentric part can bend.This bending allows the larger diameter opening during high speed operation, it is also possible to provide than dynamic The diametrically desired less control of arteries and veins actual grinding.Additionally, some stenotic tissues may stop that the passage is so complete, make Obtain Shturman equipment not knowing through there.Due to Shturman require drive shaft amplification eccentric part be arranged in it is narrow To realize grinding in narrow tissue, therefore less will have in the eccentric part amplified is stopped moving the situation in narrow place Effect.The disclosure of United States Patent (USP) No.6,494,890 is incorporated herein from there through the overall mode quoted.

United States Patent (USP) No.5, there is provided the known eccentric tissue for removing brill, drilling tool has and passes through 681,336 (Clement) Appropriate bond material is fixed to the coating of the abrasive grains of a part for its outer surface.This construction be it is limited, yet with, As described in Clement in the 53-55 rows of volume 3, asymmetric brill is rotated with " than using the lower speed of high speed ablation apparatus ", " with heat compensation or imbalance ".That is, size and quality that entity is bored are given, with the high speed used in rotary-cut program process (i.e. 20,000-200,000rpm) rotary drilling is infeasible.In fact, possible with the barycenter that the rotation axiss of drive shaft are biased Cause the development of notable eccentric force, apply too many pressure on the wall of tremulous pulse and excessive heat is formed with great granule.

Thus, permission is normally needed to increase the rotating-cutting equipment of the working diameter of grinding head, system in the art With method.

The content of the invention

The embodiment of rotary cutting apparatus includes non-oscillatory drive shaft, oscillating part, vibration drive shaft, grinding head and pulsation Device.This non-oscillatory drive shaft includes cavity and rotation axiss by which.This oscillating part includes neighbouring non-oscillatory drive shaft Distal end is fixedly attached to the radial offset drive shaft attachment of non-oscillatory drive shaft.Drive shaft attachment includes central cavity, This central cavity is with the cavity fluid communication of non-oscillatory drive shaft and consistent with the rotation axiss of non-oscillatory drive shaft.Drive shaft Attachment also includes the attachment point radially offset with central cavity.Vibration driving shaft in its proximal attachment to attachment point, and The distal end of the neighbouring vibration drive shaft of grinding head is fixedly attached to vibration drive shaft.Pulsator be configured to introduce pulsation so as to from from Blood vessel removes at least a portion of atherosis material.

Another embodiment of rotary cutting apparatus includes prime mover, drive shaft, grinding head and pulsator.Drive shaft is near at which End is rotationally coupled to prime mover and proximally to remote extension.Grinding head is regularly attached in the proximate distal ends of drive shaft To drive shaft.Pulsator is configured to introduce pulsation so as to from least a portion that atherosis material is removed from blood vessel.

Description of the drawings

Fig. 1 shows the axonometric chart of an embodiment of the invention；

Fig. 2 shows the side elevation in partial section of an embodiment of the invention；

Fig. 3 shows the side elevation in partial section of an embodiment of the invention；

Fig. 4 shows the side elevation in partial section of an embodiment of the invention；

Fig. 5 shows the end-view of an embodiment of the invention；And

Fig. 6 shows the end-view of an embodiment of the invention.

Specific embodiment

Although disclosed embodiment can be revised as various remodeling and alternate forms, in the accompanying drawings by the side of example Formula shows its detail and is described in detail its detail here.It should be understood, however, that this It is bright to be not intended to be limited to the disclosure particular implementation for describing with reference to the accompanying drawings.On the contrary, it is therefore an objective to which covering belongs to the present invention Spirit and scope in whole modifications, equivalent and alternative thing.

The different embodiments of the present invention can be included in generally as described in United States Patent (USP) No.6,494,890 In the biopsy system of entitled " eccentric rotating-cutting equipment (ECCENTRIC ROTATIONAL ATHERECTOMY DEVICE) ", its It is incorporated herein by way of reference.Additionally, below, the disclosure of joint patent or patent application is by quoting their entities Mode is incorporated herein.United States Patent (USP) No.6 of entitled " rotating-cutting equipment (ROTATIONAL ATHERECTOMY DEVICE) ", 295,712；It is entitled " to be used for the eccentric drive shaft and manufacture method (ECCENTRIC DRIVE SHAFT FOR of rotating-cutting equipment ATHERECTOMY DEVICE AND METHOD FOR MANUFACTURE) " United States Patent (USP) No.6,132,444；It is entitled " for the eccentric drive shaft and manufacture method (ECCENTRIC DRIVE SHAFT FOR ATHERECTOMY of rotating-cutting equipment DEVICE AND METHOD FOR MANUFACTURE) " United States Patent (USP) No.6,638,288；It is entitled " to be used for grinding for rotary-cut The U.S. of mill drive shaft equipment (ABRASIVE DRIVE SHAFT DEVICE FOR ROTATIONAL ATHERECTOMY) " is special Sharp No.5,314,438；United States Patent (USP) No.6 of entitled " rotating-cutting equipment (ROTATIONAL ATHERECTOMY DEVICE) ", 217,595；United States Patent (USP) No.5,554,163 of entitled " rotating-cutting equipment (ATHERECTOMY DEVICE) "；Entitled " tool There are rotation angiopoiesises equipment (the ROTATIONAL ANGIOPLASTY DEVICE WITH ABRASIVE of grinding bizet CROWN United States Patent (USP) No.7,507,245) "；It is entitled " to there is the rotating-cutting equipment of radially expandable former dynamic moving member connection (ROTATIONAL ATHERECTOMY DEVICE WITH RADIALLY EXPANDABLE PRIME MOVER COUPLING United States Patent (USP) No.6,129,734) "；It is entitled " to be used for the eccentric grinding head of high speed rotating-cutting equipment U.S. of (ECCENTRIC ABRADING HEAD FOR HIGH-SPEED ROTATIONAL ATHERECTOMY DEVICES) " State's patent No.8,597,313；It is entitled " to be used to open system, apparatus and method (SYSTEM, the APPARATUS of Occlusion AND METHOD FOR OPENING AN OCCLUDED LESION) " United States Patent (USP) No.8,439,937；It is entitled " to be used for Electric grinding element (the ECCENTRIC ABRADING ELEMENT FOR HIGH-SPEED ROTATIONAL of high speed rotating-cutting equipment ATHERECTOMY DEVICES) " U.S. Publication No.2009/0299392；It is entitled " to be used for the barycenter with transverse shifting Rotating-cutting equipment many material grinding heads (MULTI-MATERIAL ABRADING HEAD FOR ATHERECTOMY DEVICES HAVING LATERALLY DISPLACED CENTER OF MASS) " U.S. Publication No.2010/0198239；It is entitled " there is rotating-cutting equipment (the ROTATIONAL ATHERECTOMY DEVICE WITH PRE-CURVED of front curve drive shaft DRIVE SHAFT) " U.S. Publication No.0036402；It is entitled " to be used for the electric grinding and cutting element of high speed rotating-cutting equipment (ECCENTRIC ABRADING AND CUTTING HEAD FOR HIGH-SPEED ROTATIONAL ATHERECTOMY DEVICES U.S. Publication No.2009/0299391) "；It is entitled " to be used for the electric grinding and cutting head of high speed rotating-cutting equipment (ECCENTRIC ABRADING AND CUTTING HEAD FOR HIGH-SPEED ROTATIONAL ATHERECTOMY DEVICES U.S. Publication No.2010/0100110) "；It is entitled that " bizet (ROTATIONAL ATHERECTOMY are ground in rotary-cut ABRASIVE CROWN) " S Design Patent No.D610258；It is entitled that " bizet (ROTATIONAL is ground in rotary-cut ATHERECTOMY ABRASIVE CROWN) " United States Patent (USP) No.D6107102；It is entitled " can for the two-way of rotating-cutting equipment U.S. of expansion-head (BIDIRECTIONAL EXPANDABLE HEAD FOR ROTATIONAL ATHERECTOMY DEVICE) " State's patent discloses No.2009/0306689；It is entitled that " rotary-cut for improving grinding efficiency is segmented grinding head and method (ROTATIONAL ATHERECTOMY SEGMENTED ABRADING HEAD AND METHOD TO IMPROVE ABRADING EFFICIENCY) " United States Patent (USP) disclose 2010/0211088；It is entitled " to there is the rotating-cutting equipment of motor The United States Patent (USP) of (ROTATIONAL ATHERECTOMY DEVICE WITH ELECTRIC MOTOR) " discloses No.2013/ 0018398；And entitled " track rotating-cutting equipment traverse design (ORBITAL ATHERECTOMY DEVICE GUIDE WIRE DESIGN United States Patent (USP) No.7,666,202) ".It is considered herein that the feature of one or more in embodiments of the present invention One or more features can be combined with the embodiment of rotating-cutting equipment described herein.

Fig. 1 shows an embodiment of rotating-cutting equipment of the invention.This equipment includes handle portion 10；Carefully Long, flexible non-oscillatory and the thus drive shaft 20 of fixed axis, its there is cavity therethrough so that wire passes through and Also have oscillating part 100, the oscillating part adjacent to drive shaft 20 distal attachment to which and including radial deflection drive shaft Attachment 102 and the grinding head 106 installed or be additionally arranged in flexible vibration drive shaft 110.Will below further in detail Oscillating part 100 and its part and feature carefully are described.Slender conduit 13 is again shown as from handle portion 10 to remote extension. In non-oscillatory fixed axis drive shaft 20 is constructed and had by spiral winding as known in the art outer surface 24 and limits The inner surface 22 of cavity, to allow non-oscillatory drive shaft 20 on wire to advance and rotate.Conduit 13 has cavity, except shaking Swing beyond part 100, most of length of drive shaft 20 is arranged in the cavity.Fluid supply line 17 can be provided as cooling down It is incorporated in conduit 13 with lubrication solution (typically saline or another kind of biocompatible fluid).

Handle 10 is ideally containing turbine (or similar rotary drive mechanism) so as to drive shaft 20 rotate at high speed. Handle 10 normally may be coupled to the energy source of the compressed air for such as transporting through pipe 16.A pair of fiber optic cables can be used Line 25, can alternatively use single Connectorized fiber optic cabling, a pair of Connectorized fiber optic cablings, the single Connectorized fiber optic cablings of alternative can be provided for (detailed description with regard to this handle and relevant apparatus is many institute's weeks to monitoring turbine in the industry with the rotary speed of drive shaft 20 Know).Handle 10 be also ideally comprised the body propulsion relative to conduit 13 and handle with withdraw turbine with drive shaft 20 with The joystick 11 of the oscillating part 100 of attachment.

Referring now to Fig. 2, oscillating part 100 is attached to the proximate distal ends of non-oscillatory drive shaft 20, and including radially partially The grinding head 106 for moving drive shaft attachment 102 and installing or be additionally arranged in flexible vibration drive shaft 110.

Radial offset drive shaft attachment 102 includes the circular configuration of cavity placed in the middle 103 shown as ground, and radial offset drives Axle attachment is by cavity placed in the middle is consistent with 20 cavity of non-oscillatory drive shaft and fluid communication.In this construction, work as non-oscillatory When drive shaft 20 rotates, radial offset drive shaft attachment 102 will be rotated with one heart with drive shaft 20, because circular drives axle The barycenter of attachment 102 is also consistent with the rotation axiss A of non-oscillatory drive shaft 20.Fig. 2 shows that wire can pass through non-oscillatory 20 cavity of drive shaft and pass through middle chamber 103.It will be recognized by those skilled in the art drive shaft attachment 102 is illustrated The circular form of embodiment is only the one kind in the possible several forms of feature.It is required of drive shaft attachment 102 Center coordination is in the centre of middle chamber 103.

Flexible vibration drive shaft 110 with the attachment point 104 of 103 radial offset of middle chamber at be attached to radial offset drive Moving axis attachment 102.The distance of this radial offset, the rotary speed together with drive shaft 20 and the thus rotation of oscillating part 100 The quality of rotary speed and grinding head 106 determines the working diameter in operation of grinding head 106 with its position.Grinding head The increase of 106 working diameter directly with the relatively large distance between attachment point 104 and middle chamber 103, drive shaft 20 and vibration The rotary speed of the increase of part 100, and the quality of the increase of grinding head 106 to increase quality radial offset it is related.This Outward, as described below, relative to each other in fore-and-aft plane, the position of radial offset is also driven to vibration for barycenter C and attachment point 104 The bending of axle 110, and thus, the size of the working diameter realized by grinding head 106 during rotation process is had directly Connect impact.

In figs. 2 and 3 grinding head 106 be illustrated as it is concentric, i.e., with regard to by mode well known in the art It is longitudinal direction and laterally or radially symmetric construction by the vibration drive shaft 110 that grinding head is attached to which.Therefore, grind in figs. 2 and 3 The barycenter C of bistrique 106 is consistent with the rotation axiss A ' of vibration drive shaft 110.

Alternatively, as shown in Figure 4, grinding head 106 can be included with the rotation axiss A ' for vibrating drive shaft 110 radially The barycenter C of biasing.Those of skill in the art will recognize that barycenter C can be by forming with least radially or laterally several Why not symmetric geometric eccentricity pure as shown in Figure 4 or by geometrically concentric or eccentric grinding head Used in 106, the material of different densities is moved radially away from the earth relative to the rotation axiss A ' of vibration drive shaft 110.

In two kinds of situations as shown, the working diameter realized by grinding head 106 is more than its rest diameter.Can lead to Cross the attachment point 104 of the barycenter C and radial deflection drive shaft attachment 102 of the radial offset of alignment grinding head 106, utilize Fig. 4 In the technology that illustrates buffering effect is increased to into oscillating part 100 so that in attachment point 104 in the fore-and-aft plane in such as Fig. 5 There is 0 degree of biasing and the barycenter C of radial offset between.

Alternatively, as in figure 6,180 degree can be moved by the radial offset barycenter C by grinding head 106 so that radially The barycenter of biasing is positioned on the opposite side of the rotation axiss A ' of vibration drive shaft compared with attachment point 104, is strengthened vibration and is driven The bending of axle 110.

In whole situations, no matter grinding head 106 is placed in the middle or eccentric, and the work realized in high-speed rotation is straight Footpath is both greater than the working diameter of grinding head 106.

In some embodiments, the high speed rotation of grinding head 106 has to last for the time period for extending, to realize expecting Result.However, the lasting high speed rotation for being incorporated into the part in blood flow is likely to result in haemolysis.Additionally, the high speed rotation of part Heat may be produced in rotary part and in the object of the body part for including contacting with rotary part.If do not remove or Limit the heat for producing, then pyrolytic damage may subsequently occur.In some embodiments, saline is used as heat transfer fluids And/or as lubricant so that the generation of heat is minimized.Additionally, in some applications, do not damaging in addition or removing strong In the case that health is organized, polishing cannot be used for removing the excessive doped calcium for example in blood vessel, inner membrance, adventitia etc..

As with the alternative of high rotary speed operation grinding head 106 or except with high rotary speed operation grinding head 106, some embodiments of rotary cutting apparatus include pulsator, with the atheroma material for removing or destroying near grinding head 106 At least a portion of material.Pulsator is configured in some embodiments with various intensity or multi-frequency, or with various Intensity and multi-frequency will be pulsed or vibration is incorporated into treatment position.In some embodiments, pulsation can be applied for maximum Discrete force or continuous variable power between value and minima.In some embodiments, this pulsation can be applied for discrete pulsation Vitality during going here and there or being applied for special time.In some embodiments, apply the intensity of pulsation, that is, the power for applying can To be fixed or change.Addition or alternatively, the applying frequency of power can be fixed or change.

In some embodiments, in addition to spin finishing head 106, pulsation is incorporated into treatment position by pulsator.Such as This, by introducing high impact over the course for the treatment of, the low persistent period is pulsed with non-continuous, that is, is vibrated, and can adjust this rotation Cutting apparatus are to provide the appropriate shear rate of cutting surfaces, while transmission is as without the arteries and veins operated with lasting high rotation speed The equivalent track of the device of dynamic device.In some embodiments, by addition to spin finishing head 106 introduce pulsation and Spin finishing head 106 introduces pulsation simultaneously, can reduce integral-rotation speed and average rotary speed, while keeping or transmitting With the substantially similar effectively treatment provided with the lasting high rotation speed without pulsation.Also, pass through rotary speed Reduction, haemolysis and thermal shock will be reduced or eliminated.

In some embodiments, when, upon rotating or when clamped, pulsation be directed into non-oscillatory drive shaft 20, In one or more of vibration drive shaft 110 and grinding head 106.In some embodiments, can be by pulsation (or vibration) It is introduced in non-oscillatory drive shaft 20 to operate and the driving of at least non-oscillatory with one or two the mode in vibration drive shaft 110 Prime mover of 20 rotatable connection of axle.In non-restrictive example embodiment, for making prime mover and non-oscillatory drive shaft 20 The connector for removedly engaging each other is so structured that and pulsation is incorporated in non-oscillatory drive shaft 20, non-oscillatory drive shaft after And at least in part pulsation will be incorporated in vibration driving shaft 110.For example, wherein using one or more gears can revolve Turn in the embodiment of ground connection prime mover and non-oscillatory drive shaft 20, this connector can include with irregular periphery one At least one of individual or multiple gears.In some embodiments, can be by former with the operation of discrete or variable rotational speed Motivation come introduce this pulsation.For example, the rotation of motor can be interrupted by using pulse-width regulated electric machine controller.At some In embodiment, the running current that can pass through regulation peak value and/or be supplied to motor interrupts the rotation of motor.Wherein Turbine is used as in some embodiments of prime mover, and pulsator is so structured that discretely or constantly adjusts and is supplied to whirlpool One or two in the pressure of the compression fluid of turbine and flow velocity.The embodiment of description is exemplary and should not be understood To limit.As alternatively or additionally embodiment party may be will become apparent from for those of ordinary skill in the art Formula is considered as in the scope of the present disclosure with boundary.

Additionally, or alternatively, pulsator is so structured that pulsation is incorporated into non-oscillatory drive shaft 20 is driven with vibration One or two in axle 110.Additionally, pulsator is may be configured to when grinding head 106 rotates or is fixed on treatment site When pulsation is incorporated in grinding head 106.In non-restrictive example embodiment, the pulsation of such as secondary sensing pulsation is drawn Enter in one or more of drive shaft 20 and 110 and grinding head 106.For example, pulsator is so structured that Vltrasonic device, piezoelectricity Vibrator, electromechanical photoetching reshaper etc..These examples should not be understood as limiting.Such as ordinary skill in the art Alternatively or additionally embodiment may be will become apparent to be considered as in the scope of the present disclosure with boundary for personnel.

Referring back to Fig. 1, the alternative embodiment of rotary cutting apparatus does not include oscillating part 100, and grinding head 106 is substituted Ground is connected to elongated flexible drive shaft in its proximate distal ends.In this embodiment, this device include substantially with handle portion 10 similar handles, and the prime mover for being arranged in handle and being rotationally coupled in its near proximal ends and drive shaft.Dress The non-restrictive example embodiment put also include pulsator, its be configured to it is above-mentioned substantially similarly and with above-mentioned base In sheet, identical mode introduces pulsation.Therefore, for simplicity purposes, the introducing with regard to pulsator and pulsation is not repeated. However, this should not be construed as limiting.Alternatively, such as obviously all select else possibly for those of skill in the art, Increase improve, and modification be all considered as in the scope of the present disclosure and boundary.

The present invention should not be considered limited to specific embodiments described above, but be construed as covering the complete of the present invention In terms of portion.When this specification is read for those of skill in the art according to the present invention, the present invention is applicatory Various modifications, equivalent process and various structures will be apparent.

Claims (42)

1. a kind of rotary cutting apparatus, which includes：

Non-oscillatory drive shaft, the non-oscillatory drive shaft is with by its cavity, rotation axiss and distal end；

The oscillating part of the proximate distal ends of the non-vibration drive shaft is attached at, and

Pulsator, the pulsator are used to introduce at least a portion of pulsation for atherosis material is removed from blood vessel；

The oscillating component includes：Radial offset drive shaft attachment；Vibration drive shaft and grinding head；

The radial offset drive shaft attachment is fixedly attached to the non-oscillatory drive shaft；The drive shaft attachment bag Include：Central cavity, the cavity fluid communication of the central cavity and the non-oscillatory drive shaft and with the non-oscillatory The rotation axiss of drive shaft are consistent；And the attachment point radially offset from the central cavity；

The vibration drive shaft is in its proximal attachment to the attachment point；

The grinding head is fixedly attached to the vibration drive shaft in the distal end of the vibration drive shaft.

2. device according to claim 1, wherein, the pulsation includes one or two in various intensity and multi-frequency It is individual.

3. device according to claim 2, which includes prime mover, near-end of the described prime mover in the non-oscillatory drive shaft The non-oscillatory drive shaft can be nearby rotationally coupled to, wherein, the pulsator operates institute with multiple discrete rotary speeies State prime mover.

4. device according to claim 3, wherein：

Described prime mover includes motor；And

The pulsator includes pulse-width modulator, and the pulse-width modulator is supplied to the peak point current of described prime mover for adjusting With by one or two in the running current of described prime mover.

5. device according to claim 3, wherein, described prime mover includes turbine, and the pulsator is adjusted and used In pressure and the flow velocity of the compression fluid for operating described prime mover one or two.

6. device according to claim 2, which includes prime mover, wherein, the pulsator includes two or more gears, Described two or multiple gear configurations are can rotatably to couple described prime mover and institute in the near proximal ends of non-oscillatory drive shaft State non-oscillatory drive shaft.

7. device according to claim 6, wherein, the rotation of the rotary speed of described prime mover and the non-oscillatory drive shaft Rotary speed is different.

8. device according to claim 6, wherein, at least one of described two or multiple gears include irregular week Side.

9. device according to claim 2, wherein, the pulsator includes inducer.

10. device according to claim 9, wherein, the inducer is from including supersonic generator and piezoelectric vibrator Group in select.

11. devices according to claim 2, wherein, the pulsator produces in energy wave, sound wave and pressure wave It is individual or multiple.

12. devices according to claim 2, wherein, at least a portion of the pulsator is arranged in the non-oscillatory and drives In one or more at least a portion of moving axis, the vibration drive shaft and the grinding head.

13. devices according to claim 1, which includes the guiding of the cavity for extending through the non-oscillatory drive shaft Line, wherein, movement of the non-oscillatory drive shaft on the guide line promotes the oscillating part movement.

14. devices according to claim 1, wherein, the radial offset drive shaft attachment is circular.

15. devices according to claim 1, wherein, the operation of the grinding head is with diameter greater than its rest diameter.

16. devices according to claim 1, wherein, the grinding head is concentric.

17. devices according to claim 16, wherein, the barycenter of the grinding head and it is described vibration drive shaft rotary shaft Line is consistent.

18. devices according to claim 16, wherein, the barycenter of the grinding head is from the rotary shaft for vibrating drive shaft Line radially offsets.

19. devices according to claim 1, wherein, the grinding head is eccentric.

20. devices according to claim 19, wherein, the barycenter of the grinding head is from the rotary shaft for vibrating drive shaft Line radially offsets.

21. devices according to claim 1, wherein, the grinding head includes the material with different densities.

22. devices according to claim 1, wherein, at least a portion of the pulsator is arranged in the grinding head In at least a portion.

A kind of 23. devices, which includes：

Prime mover；

Drive shaft, the drive shaft include the near-end for being rotationally coupled to described prime mover and prolong from the proximate Stretch；

Grinding head, the grinding head are fixedly attached to the drive shaft in the proximate distal ends of the drive shaft；And

Pulsator, the pulsator are used to quote at least a portion of pulsation for atherosis material is removed from blood vessel.

24. devices according to claim 23, wherein, the pulsation include in various intensity and multi-frequency or Two.

25. devices according to claim 24, wherein, the pulsator is described former dynamic with multiple discrete rotary speed operations Machine.

26. devices according to claim 25, wherein：

Described prime mover includes motor；And

The pulsator includes pulse-width modulator, and the pulse-width modulator is supplied to the peak point current of described prime mover for adjusting With by one or two in the running current of described prime mover.

27. devices according to claim 25, wherein, described prime mover includes turbine, and the pulsator is adjusted For operate the pressure of the compression fluid of described prime mover and flow velocity one or two.

28. devices according to claim 24, wherein, the pulsator includes being configured to being rotationally coupled described former dynamic Two or more gears of machine and the drive shaft.

29. devices according to claim 28, wherein, the rotary speed of described prime mover is fast with the rotation of the drive shaft Degree is different.

30. devices according to claim 28, wherein, at least one of described two or multiple gears include irregular Periphery.

31. devices according to claim 24, wherein, the pulsator includes inducer.

32. devices according to claim 31, wherein, the inducer is from including supersonic generator and piezoelectric vibrator Group in select.

33. devices according to claim 24, wherein, the pulsator produces in energy wave, sound wave and pressure wave It is individual or multiple.

34. devices according to claim 24, wherein, at least a portion of the pulsator be arranged in the drive shaft with On one or two at least a portion of the grinding head.

35. devices according to claim 23, which includes the guide line of the cavity for extending through the drive shaft, wherein, Movement of the drive shaft on the guide line promotes the grinding head movement.

36. devices according to claim 23, wherein, the operation of the grinding head is with diameter greater than its rest diameter.

37. devices according to claim 23, wherein, the grinding head is concentric.

38. devices according to claim 37, wherein, the rotation axiss one of the barycenter of the grinding head and the drive shaft Cause.

39. devices according to claim 37, wherein, the rotary shaft line footpath of the barycenter of the grinding head from the drive shaft Bias to ground.

40. devices according to claim 23, wherein, the grinding head is eccentric.

41. devices according to claim 40, wherein, the rotary shaft line footpath of the barycenter of the grinding head from the drive shaft Bias to ground.

42. devices according to claim 23, wherein, the grinding head includes the material with different densities.