CN106543934A - A kind of medical antiinflammatory sterilization pressure-sensitive adhesive - Google Patents

A kind of medical antiinflammatory sterilization pressure-sensitive adhesive Download PDF

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Publication number
CN106543934A
CN106543934A CN201610857327.XA CN201610857327A CN106543934A CN 106543934 A CN106543934 A CN 106543934A CN 201610857327 A CN201610857327 A CN 201610857327A CN 106543934 A CN106543934 A CN 106543934A
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medical
extracting solution
sensitive adhesive
pressure
antiinflammatory
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梁旭
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SICHUAN SANHE MEDICAL MATERIALS CO Ltd
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SICHUAN SANHE MEDICAL MATERIALS CO Ltd
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    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
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    • C09J133/00Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Adhesives based on derivatives of such polymers
    • C09J133/04Homopolymers or copolymers of esters
    • C09J133/06Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
    • C09J133/08Homopolymers or copolymers of acrylic acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
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    • C08F218/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an acyloxy radical of a saturated carboxylic acid, of carbonic acid or of a haloformic acid
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    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10Esters
    • C08F220/12Esters of monohydric alcohols or phenols
    • C08F220/16Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
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    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
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    • C09J131/00Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an acyloxy radical of a saturated carboxylic acid, of carbonic acid, or of a haloformic acid; Adhesives based on derivatives of such polymers
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    • C09J133/00Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Adhesives based on derivatives of such polymers
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    • C09J133/00Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Adhesives based on derivatives of such polymers
    • C09J133/04Homopolymers or copolymers of esters
    • C09J133/06Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
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    • C08F220/12Esters of monohydric alcohols or phenols
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    • C08F220/18Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
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    • C08F220/12Esters of monohydric alcohols or phenols
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    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10Esters
    • C08F220/26Esters containing oxygen in addition to the carboxy oxygen
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    • C08F220/281Esters containing oxygen in addition to the carboxy oxygen containing no aromatic rings in the alcohol moiety and containing only one oxygen, e.g. furfuryl (meth)acrylate or 2-methoxyethyl (meth)acrylate

Abstract

The present invention relates to Material Field, specifically, it is related to a kind of medical antiinflammatory sterilization pressure-sensitive adhesive, including soft monomer, hard monomer, functional monomer, tackifying resin, initiator, function additive, solvent, described function additive is made up of Herba Schizonepetae extracting solution, Radix Saposhnikoviae extracting solution, Flos Lonicerae extractive solution, Fructus Forsythiae extracting solution, Radix Glycyrrhizae extract, Radix Ginseng extractive solution, skin can be prevented effectively from uncomfortable, with antiallergic, dispelling wind for relieving itching, analgesia, antiinflammatory, biocidal efficacies.

Description

A kind of medical antiinflammatory sterilization pressure-sensitive adhesive
Technical field
The present invention relates to Material Field, in particular to a kind of medical antiinflammatory sterilization pressure-sensitive adhesive.
Background technology
Pressure-sensitive adhesive be a class external force slighter compress just can with the adhesive of adherend bonding, with it is viscous it is easily, take off The property be not difficult, shell and do not damage, also referred to as adhesive sticker become in adhesive consumption most with its unique performance and feature Greatly, the most wide product of range of application, its product almost spread over packaging, automobile, transport, communication, electrical equipment, building materials, machinery, aviation, The every field such as light industry, health.Wherein, polyacrylate pressure sensitive adhesive as formula is simple, bonding scope is wide, weatherability is good, Light resistance is strong, oil resistivity is excellent, water-tolerant, there is no phase separation and the phenomenon such as migrate, and easy to operate, the more low original of price Cause, becomes major product with fastest developing speed in pressure sensitive adhesive, and its product includes pressure-sensitive tape, pressure sensitive adhesive label paper and pressure sensitive adhesive Bonding die etc., medical adhesive tape are important product categories.
Existing medical pressure-sensing adhesive only possesses gluing function mostly, does not possess antiinflammatory sterilizing function.
The content of the invention
For the problems referred to above, the present invention proposes a kind of medical antiinflammatory sterilization pressure-sensitive adhesive, can be sterilized with effective antiinflammatory.
To achieve these goals, the technical solution adopted in the present invention is, a kind of medical antiinflammatory sterilizes pressure-sensitive adhesive, Including soft monomer, hard monomer, functional monomer, tackifying resin, initiator, function additive, solvent, described function additive is by chaste tree Mustard extracting solution, Radix Saposhnikoviae extracting solution, Flos Lonicerae extractive solution, Fructus Forsythiae extracting solution, Radix Glycyrrhizae extract, Radix Ginseng extractive solution's composition.
Further, described soft monomer be butyl acrylate, one or two combinations in Isooctyl acrylate monomer.
Further, described hard monomer be methyl methacrylate, acrylic acid methyl ester., the one kind or many in vinyl acetate Plant combination.
Further, described functional monomer be acrylic acid, 2-(Acryloyloxy)ethanol, the one kind or many in Hydroxypropyl acrylate Plant combination.
Further, described tackifying resin be Colophonium, newtrex, terpene resin, one or more in polyvinyl alcohol Combination.
Further, described solvent be ethyl acetate, normal hexane, one or more combination in heptane.
Preferably, described function additive is calculated as 5~10 parts of Herba Schizonepetae extracting solution, Radix Saposhnikoviae extracting solution 8~12 by weight Part, 5~10 parts of Flos Lonicerae extractive solution, 10~15 parts of Fructus Forsythiae extracting solution, 10~15 parts of Radix Glycyrrhizae extract, Radix Ginseng extractive solution 3~8 Part.
Preferably, described Herba Schizonepetae extracting solution, Radix Saposhnikoviae extracting solution, Flos Lonicerae extractive solution, Fructus Forsythiae extracting solution, Radix Glycyrrhizae are extracted Liquid, Radix Ginseng extractive solution adopt organic extract.
Further, described function additive accounts for 3~8wt% of medical adhesive raw material.
Medical pressure-sensing adhesive of the present invention has functions that heat-clearing and toxic substances removing, can be prevented effectively from skin discomfort, tool There are antiallergic, dispelling wind for relieving itching, analgesia, antiinflammatory, biocidal efficacies.
Specific embodiment
The present invention is described in further detail below by specific embodiment.
Embodiment 1:A kind of medical antiinflammatory sterilization pressure-sensitive adhesive, including soft monomer, hard monomer, functional monomer, thickening Resin, initiator, function additive, solvent, described function additive are calculated as 8 parts of Herba Schizonepetae extracting solution, Radix Saposhnikoviae extracting solution by weight 10 parts, 8 parts of Flos Lonicerae extractive solution, 12 parts of Fructus Forsythiae extracting solution, 14 parts of Radix Glycyrrhizae extract, 5 parts of Radix Ginseng extractive solution.
Described soft monomer is butyl acrylate, one or two combinations in Isooctyl acrylate monomer.
Described hard monomer is methyl methacrylate, acrylic acid methyl ester., one or more combination in vinyl acetate.
Described functional monomer is acrylic acid, 2-(Acryloyloxy)ethanol, one or more combination in Hydroxypropyl acrylate.
Described tackifying resin is Colophonium, newtrex, terpene resin, one or more combination in polyvinyl alcohol.
Described solvent is ethyl acetate, normal hexane, one or more combination in heptane.
Described Herba Schizonepetae extracting solution, Radix Saposhnikoviae extracting solution, Flos Lonicerae extractive solution, Fructus Forsythiae extracting solution, Radix Glycyrrhizae extract, Radix Ginseng are carried Take liquid and adopt organic extract.
Described function additive accounts for the 5wt% of medical adhesive raw material.
Embodiment 2:A kind of medical antiinflammatory sterilization pressure-sensitive adhesive, including soft monomer, hard monomer, functional monomer, thickening Resin, initiator, function additive, solvent, described function additive are calculated as 5 parts of Herba Schizonepetae extracting solution, Radix Saposhnikoviae extracting solution 8 by weight Part, 5 parts of Flos Lonicerae extractive solution, 10 parts of Fructus Forsythiae extracting solution, 10 parts of Radix Glycyrrhizae extract, 3 parts of Radix Ginseng extractive solution.
Further, described soft monomer be butyl acrylate, one or two combinations in Isooctyl acrylate monomer.
Further, described hard monomer be methyl methacrylate, acrylic acid methyl ester., the one kind or many in vinyl acetate Plant combination.
Further, described functional monomer be acrylic acid, 2-(Acryloyloxy)ethanol, the one kind or many in Hydroxypropyl acrylate Plant combination.
Further, described tackifying resin be Colophonium, newtrex, terpene resin, one or more in polyvinyl alcohol Combination.
Further, described solvent be ethyl acetate, normal hexane, one or more combination in heptane.
Described Herba Schizonepetae extracting solution, Radix Saposhnikoviae extracting solution, Flos Lonicerae extractive solution, Fructus Forsythiae extracting solution, Radix Glycyrrhizae extract, Radix Ginseng are carried Take liquid and adopt organic extract.
Further, described function additive accounts for the 8wt% of medical adhesive raw material.
Embodiment 3:A kind of medical antiinflammatory sterilization pressure-sensitive adhesive, including soft monomer, hard monomer, functional monomer, thickening Resin, initiator, function additive, solvent, described function additive are calculated as 10 parts of Herba Schizonepetae extracting solution, Radix Saposhnikoviae extracting solution by weight 12 parts, 10 parts of Flos Lonicerae extractive solution, 15 parts of Fructus Forsythiae extracting solution, 15 parts of Radix Glycyrrhizae extract, 8 parts of Radix Ginseng extractive solution.
Described soft monomer is butyl acrylate, one or two combinations in Isooctyl acrylate monomer.
Described hard monomer is methyl methacrylate, acrylic acid methyl ester., one or more combination in vinyl acetate.
Described functional monomer is acrylic acid, 2-(Acryloyloxy)ethanol, one or more combination in Hydroxypropyl acrylate.
Described tackifying resin is Colophonium, newtrex, terpene resin, one or more combination in polyvinyl alcohol.
Described solvent is ethyl acetate, normal hexane, one or more combination in heptane.
Described function additive accounts for the 3wt% of medical adhesive raw material.
Embodiment 4:A kind of medical antiinflammatory sterilization pressure-sensitive adhesive, including soft monomer, hard monomer, functional monomer, thickening Resin, initiator, function additive, solvent, described function additive are calculated as 8 parts of Herba Schizonepetae extracting solution, Radix Saposhnikoviae extracting solution by weight 10 parts, 7 parts of Flos Lonicerae extractive solution, 12 parts of Fructus Forsythiae extracting solution, 12 parts of Radix Glycyrrhizae extract, 5 parts of Radix Ginseng extractive solution.
The preferred embodiments of the present invention are the foregoing is only, the present invention is not limited to, for the skill of this area For art personnel, there can be various modifications and variations in the spirit and principles in the present invention, the modification of these equivalents or replacement etc., It is all contained within protection scope of the present invention.

Claims (9)

1. a kind of medical antiinflammatory sterilizes pressure-sensitive adhesive, including soft monomer, hard monomer, functional monomer, tackifying resin, initiation Agent, solvent, it is characterised in that:Also include function additive, described function additive is by Herba Schizonepetae extracting solution, Radix Saposhnikoviae extracting solution, gold silver Flower extracting solution, Fructus Forsythiae extracting solution, Radix Glycyrrhizae extract, Radix Ginseng extractive solution's composition.
2. a kind of medical antiinflammatory according to claim 1 sterilizes pressure-sensitive adhesive, it is characterised in that:Described soft monomer is One or two combinations in butyl acrylate, Isooctyl acrylate monomer.
3. a kind of medical antiinflammatory according to claim 1 sterilizes pressure-sensitive adhesive, it is characterised in that:Described hard monomer is One or more combination in methyl methacrylate, acrylic acid methyl ester., vinyl acetate.
4. a kind of medical antiinflammatory according to claim 1 sterilizes pressure-sensitive adhesive, it is characterised in that:Described feature list Body is acrylic acid, 2-(Acryloyloxy)ethanol, one or more combination in Hydroxypropyl acrylate.
5. a kind of medical antiinflammatory according to claim 1 sterilizes pressure-sensitive adhesive, it is characterised in that:Described tackifying resin Combine for one or more in Colophonium, newtrex, terpene resin, polyvinyl alcohol.
6. a kind of medical antiinflammatory according to claim 1 sterilizes pressure-sensitive adhesive, it is characterised in that:Described solvent is second One or more combination in acetoacetic ester, normal hexane, heptane.
7. a kind of medical antiinflammatory according to claim 1 sterilizes pressure-sensitive adhesive, it is characterised in that:Described function additive It is calculated as 5~10 parts of Herba Schizonepetae extracting solution, 8~12 parts of Radix Saposhnikoviae extracting solution, 5~10 parts of Flos Lonicerae extractive solution, Fructus Forsythiae by weight to extract 10~15 parts of liquid, 10~15 parts of Radix Glycyrrhizae extract, 3~8 parts of Radix Ginseng extractive solution.
8. a kind of medical antiinflammatory sterilization pressure-sensitive adhesive according to claim 1 or 7, it is characterised in that:Described Herba Schizonepetae Extracting solution, Radix Saposhnikoviae extracting solution, Flos Lonicerae extractive solution, Fructus Forsythiae extracting solution, Radix Glycyrrhizae extract, Radix Ginseng extractive solution adopt organic extraction Liquid.
9. a kind of medical antiinflammatory according to claim 1 sterilizes pressure-sensitive adhesive, it is characterised in that:Described function additive Account for 3~8wt% of medical adhesive raw material.
CN201610857327.XA 2016-09-28 2016-09-28 A kind of medical antiinflammatory sterilization pressure-sensitive adhesive Pending CN106543934A (en)

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CN113122166A (en) * 2021-04-19 2021-07-16 黑龙江大学 Composite antibacterial pressure-sensitive adhesive composition and preparation method thereof

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CN105219317A (en) * 2015-11-12 2016-01-06 四川厚生天佐药业有限公司 A kind of medical polyacrylate pressure-sensitive adhesive of environmental protection sticks agent

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CN113122166B (en) * 2021-04-19 2023-10-20 黑龙江大学 Composite antibacterial pressure-sensitive adhesive composition and preparation method thereof

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