CN106543128A - A kind of anthocyanidin extractive technique - Google Patents
A kind of anthocyanidin extractive technique Download PDFInfo
- Publication number
- CN106543128A CN106543128A CN201610845383.1A CN201610845383A CN106543128A CN 106543128 A CN106543128 A CN 106543128A CN 201610845383 A CN201610845383 A CN 201610845383A CN 106543128 A CN106543128 A CN 106543128A
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- Prior art keywords
- anthocyanidin
- leachate
- extractive technique
- film
- obtaining
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
- C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
The invention provides a kind of anthocyanidin extractive technique, extraction process step includes：It is step one, broken；Step 2, coarse filtration；Step 3, fine straining；Step 4, concentration；Step 5, solvent extraction；Step 6, spray drying；Step；7th, adsorb, the anthocyanidin good stability extracted by the present invention, functionality active component extraction ratio is high, purity is high, and system long service life, film contamination resistance are strong, and regenerability is good, can realize high disposal flux and stable seriality automated production for a long time.
Description
Technical field
The present invention relates to membrane technology field, particularly a kind of anthocyanidin extractive technique.
Background technology
Anthocyanidin is the supplementary of the defying age of pure natural, and research proves mankind nowadays and finds maximally effective antioxygen
Agent, its antioxygenic property are higher by 50 times than Vitamin E, are higher by 20 times than vitamin C.Its biologically effective to human body
Property be 100%, take after just can detect in blood within 20 minutes.Anthocyanidin is referred to as " oral skin cosmetic in Europe
Product " still its vaccinium oxycoccus pigment, skin nutrition strengthen skin immunization power, tackle various allergic conditions.The discovery of Lycium ruthenicum Murr., top
Covered the fruit that original blue berry is the king containing anthocyanidin, anthocyanidin contained by Lycium ruthenicum Murr. be several times of blue berry even more than ten times it
It is many, the flowing that is stable, strengthening capillary vessel circulation, raising blood capillary and vein of normal cell linkages, blood vessel can be also maintained,
And then reach the rapid healing of abnormal skin.Anthocyanidin is natural sunlight overcover, is prevented from ultraviolet damage skin, skin
Skin belongs to connective tissue, and collagen protein contained therein and rigid albumen play an important role to the total of skin.
Traditional technique consumes substantial amounts of organic reagent, complex operation, and apparatus expensive, reagent loss are larger, directly use water
Extract, with it is with low cost, extraction process is simple the characteristics of.In sucking filtration operation, filter medium precision is low, and belongs to dead end mistake
Filter, filtrate quality are unstable, can bring more impurity into, and yield is relatively low.
The content of the invention
It is an object of the invention to provide a kind of anthocyanidin extractive technique.
A kind of anthocyanidin extractive technique, it is characterised in that extraction process step includes：
It is step one, broken：Being put into after Semen sojae atricolor is cleaned carries out broken leaching, obtains the leachate containing black-soybean dregs；
Step 2, coarse filtration：Leachate containing black-soybean dregs is carried out into coarse filtration process, larger granule is removed, is obtained
Thick leachate；
Step 3, fine straining：The thick leachate for obtaining is put into ultrafilter membrane carries out fine straining process, removes egg larger in the middle of leachate
White matter and other impurities；
Step 4, concentration：The leachate that fine straining is crossed is put in film carries out concentration；
Step 5, solvent extraction：The leachate for obtaining is extracted repeatedly, unnecessary aqueous phase substance is removed；
Step 6, spray drying：The anthocyanidin organic faciess for obtaining are carried out into further dried；
Step 7, absorption：The organic faciess for obtaining are put into into ion exchange resin, anthocyanidin are adsorbed using ion exchange resin.
Preferably, the step one, black-soybean dregs are carried out in water crushing leaching by waterproof pulverization.
Preferably, macro-molecular protein and large particulate matter are slightly carried, membrane element by the step 3 by ultrafilter membrane
The material of part has cellulose acetate film (CA) to composite membrane (PA), polyamide patent sandwich diaphragm, polysulfones (PS) material film, gathers
Vinylidene (PVDF) material film, and modified polyacrylonitrile（PAN）Material film.
Preferably, the step 4, carries out concentration by NF membrane, and its molecular weight cut off is 100-1000 or so,
Surface apertures are in nanoscale, also referred to as nanometer film, using acetic acid, Triafol T（CA、CTA）For main material manufacture
Nanofiltration separation membrane.
Preferably, the organic faciess for leaching are processed by the step 6 by spray dryer.
Preferably, the step 7, is processed by ion exchange resin, and ion exchange resin is with styrene and diethyl
Cross-linking products of the alkene benzene for skeleton, along with corresponding functional group such as sulfonic group or quaternary ammonium, are mandruka columnar structure
Skeleton, there are a large amount of permanent micropores inside, then imports cation exchange groups and make, and has minute aperture and big mesh, wetting resin
Aperture up to 100～500nm.
Advantages of the present invention：
1st, filtering accuracy is high, fundamentally ensure that the formedness of the degree of purity and quality of filtrate.
2nd, membrane process is pure physical process, and without phase transformation, energy consumption is low, and system is operated at normal temperatures, overcomes heat to enzyme preparation
The destruction of active substance in product.
3rd, compare traditional filtering technique, product quality is not only improved, and product yield and production efficiency have compared with
For significant raising.
4th, loss of effective components is reduced, reduces BOD and COD contents in waste water.With traditional filtration, concentration technology method phase
Inorganic salt in technical process, organic solvent can be significantly saved than, new technology, the production cost of product is reduced.
5th, the supporting control section advanced design of membranous system, so that the more aobvious simplicity of the operation and maintenance of system, significantly
Reduce the labor intensity of workman.
Description of the drawings
Implementing procedure figure of the accompanying drawing 1 for the present invention.
Specific embodiment
The present invention is further described in detail in conjunction with accompanying drawing 1 and specific embodiment.
Specific embodiment making step is as follows：
A kind of anthocyanidin extractive technique, it is characterised in that extraction process step includes：
It is step one, broken：Being put into after Semen sojae atricolor is cleaned carries out broken leaching, obtains the leachate containing black-soybean dregs；
Step 2, coarse filtration：Leachate containing black-soybean dregs is carried out into coarse filtration process, larger granule is removed, is obtained
Thick leachate；
Step 3, fine straining：The thick leachate for obtaining is put into ultrafilter membrane carries out fine straining process, removes egg larger in the middle of leachate
White matter and other impurities；
Step 4, concentration：The leachate that fine straining is crossed is put in film carries out concentration；
Step 5, solvent extraction：The leachate for obtaining is extracted repeatedly, unnecessary aqueous phase substance is removed；
Step 6, spray drying：The anthocyanidin organic faciess for obtaining are carried out into further dried；
Step 7, absorption：The organic faciess for obtaining are put into into ion exchange resin, anthocyanidin are adsorbed using ion exchange resin.
The step one, black-soybean dregs are carried out in water crushing leaching by waterproof pulverization.The step 3, by super
Macro-molecular protein and large particulate matter are slightly carried by filter membrane, and the material of membrane component has cellulose acetate film (CA) to composite membrane
(PA), polyamide patent sandwich diaphragm, polysulfones (PS) material film, Kynoar (PVDF) material film, and modified poly- third
Alkene nitrile（PAN）Material film.The step 4, carries out concentration by NF membrane, and its molecular weight cut off is 100-1000 or so,
Surface apertures are in nanoscale, also referred to as nanometer film, using acetic acid, Triafol T（CA、CTA）For main material manufacture
Nanofiltration separation membrane.The organic faciess for leaching are processed by the step 6 by spray dryer.The step 7, passes through
Ion exchange resin is processed, cross-linking products of the ion exchange resin with styrene and divinylbenzene as skeleton, along with phase
The functional group answered such as sulfonic group or quaternary ammonium, are the skeleton of mandruka columnar structure, and there are a large amount of permanent micropores inside,
Cation exchange groups being imported again to make, having minute aperture and a big mesh, the aperture of wetting resin is up to 100～500nm.
The present invention specifically shows and describes the present invention with reference to preferred embodiment, it is clear that the present invention is implemented not
Limited by aforesaid way, as long as employing the various unsubstantialities improvement that method of the present invention design and technical scheme are carried out,
Or it is not improved the design of invention and technical scheme are directly applied to into other occasions, protection scope of the present invention it
It is interior.
Claims (6)
1. a kind of anthocyanidin extractive technique, it is characterised in that extraction process step includes：
It is step one, broken：Being put into after Semen sojae atricolor is cleaned carries out broken leaching, obtains the leachate containing black-soybean dregs；
Step 2, coarse filtration：Leachate containing black-soybean dregs is carried out into coarse filtration process, larger granule is removed, is obtained
Thick leachate；
Step 3, fine straining：The thick leachate for obtaining is put into ultrafilter membrane carries out fine straining process, removes egg larger in the middle of leachate
White matter and other impurities；
Step 4, concentration：The leachate that fine straining is crossed is put in film carries out concentration；
Step 5, solvent extraction：The leachate for obtaining is extracted repeatedly, unnecessary aqueous phase substance is removed；
Step 6, spray drying：The anthocyanidin organic faciess for obtaining are carried out into further dried；
Step 7, absorption：The organic faciess for obtaining are put into into ion exchange resin, anthocyanidin are adsorbed using ion exchange resin.
2. a kind of anthocyanidin extractive technique according to claims 1, it is characterised in that the step one, by wet method
Crushing, black-soybean dregs are carried out in water crushing leaching.
3. a kind of anthocyanidin extractive technique according to claims 1, it is characterised in that the step 3, by ultrafiltration
Macro-molecular protein and large particulate matter are slightly carried by film, and the material of membrane component has cellulose acetate film (CA) to composite membrane
(PA), polyamide patent sandwich diaphragm, polysulfones (PS) material film, Kynoar (PVDF) material film, and modified poly- third
Alkene nitrile（PAN）Material film.
4. a kind of anthocyanidin extractive technique according to claims 1, it is characterised in that the step 4, by nanofiltration
Film carries out concentration, and its molecular weight cut off is 100-1000 or so, and surface apertures are in nanoscale, also referred to as nanometer film,
Using acetic acid, Triafol T（CA、CTA）For the nanofiltration separation membrane of main material manufacture.
5. a kind of anthocyanidin extractive technique according to claims 1, it is characterised in that the step 6, by spraying
Drying machine is processed to the organic faciess for leaching.
6. a kind of anthocyanidin extractive technique according to claims 1, it is characterised in that the step 7, by ion
Exchanger resin is processed, cross-linking products of the ion exchange resin with styrene and divinylbenzene as skeleton, along with corresponding
Functional group such as sulfonic group or quaternary ammonium, are the skeleton of mandruka columnar structure, and there are a large amount of permanent micropores inside, then leads
Enter cation exchange groups to make, have minute aperture and a big mesh, the aperture of wetting resin is up to 100～500nm.
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| CN201610845383.1A CN106543128A (en) | 2016-09-24 | 2016-09-24 | A kind of anthocyanidin extractive technique |
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| CN201610845383.1A CN106543128A (en) | 2016-09-24 | 2016-09-24 | A kind of anthocyanidin extractive technique |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107266409A (en) * | 2017-08-20 | 2017-10-20 | 合肥信达膜科技有限公司 | A kind of dynamical anthocyanidin extracting method |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101102783B (en) * | 2006-12-13 | 2010-11-17 | 北京绿色金可生物技术股份有限公司 | Black soybean seedcoat extract and its extracting method and application |
| CN101125844B (en) * | 2007-09-28 | 2011-04-06 | 天津市尖峰天然产物研究开发有限公司 | Method for extracting procyanidins B2 |
| CN102633764A (en) * | 2012-03-26 | 2012-08-15 | 安徽尚善生物科技有限公司 | Production process for preparing anthocyanin and pectin by black soya bean hull |
| CN102942550A (en) * | 2012-12-04 | 2013-02-27 | 江苏久吾高科技股份有限公司 | Method for extracting cyanidin from black bean peel |
-
2016
- 2016-09-24 CN CN201610845383.1A patent/CN106543128A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101102783B (en) * | 2006-12-13 | 2010-11-17 | 北京绿色金可生物技术股份有限公司 | Black soybean seedcoat extract and its extracting method and application |
| CN101125844B (en) * | 2007-09-28 | 2011-04-06 | 天津市尖峰天然产物研究开发有限公司 | Method for extracting procyanidins B2 |
| CN102633764A (en) * | 2012-03-26 | 2012-08-15 | 安徽尚善生物科技有限公司 | Production process for preparing anthocyanin and pectin by black soya bean hull |
| CN102942550A (en) * | 2012-12-04 | 2013-02-27 | 江苏久吾高科技股份有限公司 | Method for extracting cyanidin from black bean peel |
Non-Patent Citations (1)
| Title |
|---|
| 李新: "黑豆皮花青素性质及抑制肿瘤细胞增殖的研究", 《中国优秀硕士学位论文全文数据库》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107266409A (en) * | 2017-08-20 | 2017-10-20 | 合肥信达膜科技有限公司 | A kind of dynamical anthocyanidin extracting method |
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Application publication date: 20170329 |