CN106535870A

CN106535870A - Cosmetic

Info

Publication number: CN106535870A
Application number: CN201680000928.7A
Authority: CN
Inventors: 王伟平
Original assignee: Shanghai Water Fitness Cosmetics Co Ltd
Current assignee: Shanghai Water Fitness Cosmetics Co Ltd
Priority date: 2016-06-30
Filing date: 2016-06-30
Publication date: 2017-03-22
Also published as: WO2018000296A1

Abstract

The present invention relates to a peelable cosmetic composition comprising a 20 wt% to 50 wt% aqueous polyurethane dispersion and 1 wt% to 10 wt% aqueous acrylic acid dispersion, and a process for producing the same. The compositions are particularly useful as finger / nail varnishes

Description

Cosmetics

The present invention relates to peelable cosmetic composition and its production method.The compositionss are particularly useful as finger/toe First varnish.

Background technology

Cosmetics are widely used for modifying or improving its appearance by individuality, such as in response to faddish trend or as individual character Show.The cosmetics of known numerous species, most popular some cosmetics are those for changing finger/toenail outward appearance.Its In, it is commonly called as especially welcome for the preparation of finger/toenail " varnish " or " polishing agent ", this is due to having broad range of color and decorations Face (finish) can use.The market of finger/toenail varnish is global, and global annual sales amount is more than 1,000,000,000 dollars.

Finger/toenail varnish generally comprises dissolving film forming polymer in organic solvent.Conventional formulation can be included and is dissolved in Such as NC Nitroncellulose polymer in butyl acetate or ethyl acetate.However, such film is often frangible for property, because This, in order to provide a certain degree of flexibility so as to prevent varnish from rupturing in finger/toenail, generally adds plasticizer.Common increasing Modeling agent is phthalic acid ester such as dibutyl phthalate.Generally also it is polymerized comprising binding agent in finger/toenail varnish formulations Thing such as tosyl amine-for-aldehyde, to promote varnish to adhere to the keratinous surfaces of finger/toenail.Other common additives include Toluene and formaldehyde (generally in aqueous).Due to the presence of such compound, finger/toenail varnish is considered as poisonous to people, And hazardous material is classified as in some areas, its storage and process are controlled.

The administration and removal of conventional finger/toenail varnish there is also problem.These solvent base finger/toenail varnish are done after application It is dry slow, it is sufficient to be hardened to and avoid obscuring, defile or be transferred to the usual needs of other surfaces 10 minutes to 1 hour.It is present in so Varnish in solvent generally have strong abnormal smells from the patient, cause closing place or public place be inconvenient to apply.Once apply, Conventional solvent base finger/toenail varnish needs by the solubilising in appropriate organic solvent to remove.It is most commonly used for Except the solvent of finger/toenail varnish is acetone, but acetone evaporate on skin feel unpleasant, and skin exposes repeatedly Can cause to be dried or be cracked in acetone.Replacement solvent such as ethyl acetate is had pointed out, but as acetone, these solvents have strong Strong abnormal smells from the patient causes to make them inappropriate for applying in the space of closing.The ethyl acetate of high exposure level can cause thorn by suction Swash.

These focus cause to need to identify it is nontoxic and harmless and can be employed without worrying the finger for impairing health/ Toenail varnish formulations.Also need to rapid draing and the finger/toenail varnish that can be readily removable.

It is commercially available many finger/toenail varnish formulations based on water.Although these preparations are generally not as often The solvent base varnish of rule is poisonous like that, but they generally require to apply specific removal solution (" remover ") to remove.These Remover generally comprises alcohol and usually comprising surfactant to dissolve varnish from finger/toenail surface, removes the administration of solution May be inconvenient.If additionally, allowing varnish to retain the long period in finger/toenail, which is likely difficult to remove, in such case Under, it may be necessary to make finger/toenail grow into a part of degree that can be safely removed of the finger/toenail for scribbling varnish.In fact It is existing to need several weeks.

It is, therefore, apparent that needing the nontoxic water base finger/toenail varnish that can be readily removable and remove without the need for administration solution.

The content of the invention

The inventors discovered that, compositionss described herein are beneficial to as nontoxic water base finger/toenail varnish.Said composition is A kind of aqueous solution containing extremely low Volatile Organic Content (VOC)；Which is tasteless, and without to people, the skin particularly to people Or the composition that finger/toenail is harmful.Said composition quickly forms film under body temperature (25 DEG C -35 DEG C), and produces reservation Conventional solvents The film of the beneficial visual benefits of base finger/toenail varnish.Material that said composition easily can be applied from which remove and need not Using any removal solution；Especially, the film for being formed by said composition can be easily complete or substantially complete by peeling off Site preparation is removed.

Therefore, the invention provides a kind of peelable cosmetic composition, which includes：

The aqueous pu dispersions of 20wt% to 50wt%；With

The water soluble acrylic acid dispersion of 1wt% to 10wt%.

Present invention also offers a kind of method of the peelable compositionss for producing the present invention, methods described includes：

- in about 50 DEG C to about 70 DEG C of temperature in aqueous pu dispersions described in heating under vacuum and the aqueous acrylamide Sour dispersion at least 96 hours；Then

- optionally add one or more stabilizer, rheological agent, wetting agent and sedimentation agent and defoamer；Then

- optionally add one or more coloring agent and/or a kind of excessively more kinds of effect pigments.

Present invention also offers a kind of peelable finger/toenail varnish, which includes the peelable cosmetic composition of the present invention Or comprising the compositionss obtained by the inventive method.

Specific embodiment

C used herein₁To C₁₀Alkyl is the straight or branched alkyl containing 1 to 10 carbon atom.Generally, C₁To C₁₀Alkyl is C₁To C₆Alkyl, which is the straight or branched alkyl containing 1 to 6 carbon atom.Generally, C₁To C₆Alkyl is C₁To C₄Alkyl, which is Straight or branched alkyl containing 1 to 4 carbon atom.C₁To C₆The example of alkyl includes methyl, ethyl, n-pro-pyl, isopropyl, just Butyl, sec-butyl, the tert-butyl group, amyl group and hexyl.C₁To C₄Alkyl is typically C₁To C₂Alkyl, such as methyl or ethyl, typically Ethyl.For avoiding query, when there is two alkyl, the alkyl can be with identical or different.

C used herein₂To C₆Thiazolinyl is containing 2 to 6 carbon atoms and has one or more (such as one or two) The straight or branched thiazolinyl of double bond.C₂To C₆The example of thiazolinyl includes vinyl, acrylic, cyclobutenyl, pentenyl and hexenyl. Generally, C₂To C₆Thiazolinyl is C₂To C₄Thiazolinyl, such as vinyl, acrylic or cyclobutenyl, more generally, vinyl or acrylic. For avoiding query, when there is two thiazolinyls, the thiazolinyl can be with identical or different.

Aryl used herein is being substituted or being unsubstituted, monocyclic or condensed polycyclc aromatic group.The reality of aryl Example is included in C of the loop section containing 6 to 10 carbon atoms₆To C₁₀Aryl.Example includes phenyl (i.e. monocyclic), naphthyl, indenyl and indenes Full base (that is, condensed-bicyclic).It is preferred that phenyl.

It is that alkyl used herein, thiazolinyl or aryl can be unsubstituted or be substituted.The alkyl or alkenyl being substituted The C that one to three (for example, one or two) is selected from halogen, OH, is unsubstituted is carried generally₁To C₂Alkoxyl and-NH₂ In a substituent group.What alkyl can be perfluorinated.When alkyl is included in polyhydric alcohol, its can include 2 or more, example Such as 2 to 6 alcohol (OH) bases, such as 2,3 or 4, preferably 2 alcohol radicals.

The salt of compound used herein is the salt with one or more suitable acid or alkali.Suitable acid include mineral acid and Both organic acid, the mineral acid for example hydrochloric acid, sulphuric acid, sulfamic acid, phosphoric acid, pyrophosphoric acid, hydrobromic acid, hydroiodic acid, Fluohydric acid., Boric acid, iodic acid, Tetrafluoroboric acid or nitric acid, the organic acids for example citric acid, fumaric acid, maleic acid, malic acid, ascorbic acid, Succinic acid, tartaric acid, benzoic acid, acetic acid, Folic Acid, formic acid, lactic acid, maleic acid, oxalic acid, phthalic acid, pyridine are to toluene sulphur Change methanesulfonic acid, ethylenediaminetetraacetic acid, ethyl sulfonic acid, benzenesulfonic acid or p-methyl benzenesulfonic acid.Suitable alkali include alkali metal (for example sodium or Potassium) and alkaline-earth metal (such as calcium or magnesium) hydroxide and carbonate, and organic bases such as amine, including alkylamine, aralkyl Base amine and heterocyclic amine.

The compositionss of the present invention are adapted for use as finger/toenail varnish.Finger/toenail varnish (also referred to as finger/toenail polishing agent) It is the general name for giving the broad range of compositionss that can be applied to keratin materials (finger/toenail of such as human or animal).Term refers to/ Toenail varnish and finger/toenail polishing agent can be with used interchangeablies.The material for being applied finger/toenail varnish is referred to as into " base material ".Can be with Finger/toenail varnish is applied to into broad range of base material.The base material is typically the finger/toenail of human or animal, more generally people Finger/toenail, the finger/toenail of such as women.Typically, finger/toenail varnish is suitable for the administration of cosmetic purpose.Generally, this is applied Purpose be change base material outward appearance, such as color or glittering (" jaqan ").Finger/toenail varnish can also be applied with by providing Can prevent that base material from splitting or the protective coating that divides is strengthening base material.

The compositionss of the present invention include aqueous pu dispersions.Any suitable polyurethane resin can be used.It is preferred that Ground, the dispersions of polyurethanes is the dispersion of ion waterborne polyurethane resin, such as anion aqueous polyurethane resin.Polyurethane Resin solidifies with the evaporation of water being included in aqueous dispersion.Preferably, polyurethane resin can be at ambient temperature Solidification, such as 0 DEG C to 50 DEG C, more preferably 10 DEG C to 40 DEG C, still more preferably 20 DEG C to 37 DEG C, such as 25 DEG C to 35 DEG C, such as 30 ℃.Preferably, the dispersions of polyurethanes is substantially free of monomer, is more preferably entirely free of monomer.

Preferably, the dispersions of polyurethanes includes the solid of (wt%) 20% to 60% by weight, more preferably 30wt% To 50wt%, still more preferably 35wt% to 45wt%, such as 38wt% to 43wt%, such as 40wt% to 42wt%, e.g., from about 41wt%.Generally, solid percentage refers to that urethane solid accounts for the percentage ratio of dispersions of polyurethanes in dispersions.Generally, The dispersion 23 DEG C viscosity be 100m Pa.s to 2500mPa.s, the 0mPa.s of more generally 100mPa.s to 100, for example 100mPa.s to 500mPa.s.

Preferably, the dispersions of polyurethanes comprising glass transition temperature be 30 DEG C or lower, more preferably 0 DEG C or lower, Be still more preferably from -30 DEG C or lower such as less than -40 DEG C of polyurethane.Preferably, the elongation factor of the polyurethane (is defined as breaking Elongation when splitting) it is at least 500%, more preferably at least 800%, still more preferably at least 1100%, for example, at least 1400% or at least 1500%.Preferably, the polyurethane 100% elongation when tensile strength be 1 to 10MPa, preferably 1.5 to 5MPa, such as 2 to 4MPa, e.g., from about 2MPa, about 3MPa or about 4MPa.Preferably, tensile strength of the polyurethane in fracture For 25 to 75MPa, e.g., from about more preferably 30 to 50MPa, such as 35 to 45MPa, 40MPa.

Polyurethane generally by making part of the per molecule containing two or more NCOs and per molecule containing two or The polyhydric alcohol of more alcohol (- OH) groups reacts in the presence of a catalyst and prepares.Generally, dispersions of polyurethanes is included and is passed through Make (i) diisocyanate, () polyhydric alcohol and polyurethane obtained in (iii) dicarboxyl acid reaction.Typical diisocyanate () bag Include isophorone diisocyanate, isocyanatometyl ethylo benzene, 5- isocyanate group -1- (isocyanatomethyl) -1,3,3- front threes Butylcyclohexane, a tetramethylene xylene diisocyanate, methylene biscyclohexyl diisocyanate, two Carbimide. of hexa-methylene Ester, dicyclohexyl methyl hydride diisocyanate and toluene di-isocyanate(TDI).It is preferred that hexamethylene diisocyanate and dicyclohexyl first Alkane diisocyanate.Typical polyhydric alcohol () include hexanediol, neopentyl glycol, Propylene Glycol, ethylene glycol, dihydromethyl propionic acid, Trimethylolpropane, polytetramethylene ether diol, polytetramethylene glycol, oxa- ring in heptan -2- ketone/2,2- dimethyl -1,3- Propylene Glycol is altogether Polymers, 1,4- butanediols, hexanediol and polyethylene-poly- (tetramethylene) glycol.It is preferred that hexanediol and neopentyl glycol.Typical two Carboxylic acid () includes adipic acid and M-phthalic acid.It is preferred that adipic acid.

Generally, sour such as sulfonic acid (such as N- (2- amino-ethyls) -3- taurines or its salt) can also be added And/or diamidogen, such as ethylenediamine.The reaction is generally needed using catalyst such as tertiary amine (for example, Isosorbide-5-Nitrae-diazabicyclo [2.2.2] octane, dibutyl tin laurate or Bismuth Octoate).

For example, the dispersions of polyurethanes can include polyurethane -34 or polyurethane -35 (both at INCI titles).Poly- ammonia Ester -34 is the composition polymer formed in multistep reaction, in the multistep reaction, hexanediol, neopentyl glycol and adipic acid Copolymer and hexamethylene diisocyanate react, resulting polymers further with N- (2- amino-ethyls) -3- amino second sulphurs Acid and reacting ethylenediamine.Polyurethane -35 be adipic acid, dicyclohexyl methyl hydride diisocyanate, ethylenediamine, hexanediol, new penta 2 The copolymer of alcohol and N- (2- amino-ethyls) -3- taurine sodium monomers.Most preferably, the dispersions of polyurethanes includes poly- ammonia Ester -35.Polyurethane -34 and polyurethane -35 are commercially available, such as Baycusan C 1000 and Baycusan C 1004 (being all from Bayer).Preferably, the dispersions of polyurethanes includes only one kind of polyurethane, such as polyurethane -35.

The compositionss of the present invention include 20wt% to 50wt%, more preferably 25wt% to 40wt%, still more preferably 30wt% To the aqueous pu dispersions of 35wt% e.g., from about 31wt%, about 32wt%, about 33wt% or about 34 weight %.

The compositionss of the present invention include water soluble acrylic acid dispersion.The water soluble acrylic acid dispersion includes following material Copolymer：() one or more acidiferous monomer or its ester or its salt, which includes the part shown in formula (I)；(ii) it is a kind of or Various polyhydric alcohol.The copolymer preferably self-crosslinking.

Preferably comprising unsaturated carboxylic acid, such as alpha-beta ethylene type carboxylic acid, which can be selected from propylene to the acidiferous monomer Acid, methacrylic acid .beta.-methylacrylic acid, maleic acid, itaconic acid, glutaconate, mesaconic acid and its derivant.The derivant of acid can be such as The C for be selected from halogen, being unsubstituted₁To C₃Alkyl, the C being unsubstituted₁To C₂Alkoxyl and-NH₂One or two, preferably one Individual substituent group is replaced.Preferably, the acid for being used is methacrylic acid, acrylic acid or .beta.-methylacrylic acid, and more preferably described acid is first Base acrylic acid or acrylic acid, most preferably described acid is methacrylic acid.

Ester of the ester of acidiferous monomer preferably for any acidiferous monomer described herein；And preferably methacrylic acid, third The ester of olefin(e) acid or .beta.-methylacrylic acid, more preferably methacrylic acid or acrylic acid ester, the acrylic acid ester of most preferable.Ester can generally lead to Cross the hydroxy-acid group reaction of alcohol and acidiferous monomer and formed.The alcohol can be alkylol or aryl alcohol.When alcohol is alkylol, Ester is Arrcostab.When alcohol is aryl alcohol, ester is aryl ester.The ester is preferably Arrcostab.Arrcostab can contain this paper institutes The C of definition₁To C₁₀Alkyl, its can be unsubstituted, be perfluorinated or the C that is selected from halogen ,-OH, is unsubstituted₁ To C₂Alkoxyl and-NH₂1,2 or 3 substituent groups replaced.Preferably, the alkyl is C₁To C₆Alkyl, which is without taking Generation, be perfluorinated or be selected from halogen ,-OH and the C being unsubstituted₁To C₂1 or 2 substituent group of alkoxyl is replaced. It is highly preferred that the alkyl is C₁To C₄Alkyl, its be unsubstituted, be perfluorinated or being selected from halogen and-OH 1 Individual substituent group is replaced, and still more preferably, the alkyl is C₁To C₃Alkyl is which is unsubstituted or replaced by halogen；Most Preferably, the alkyl is unsubstituted.Aryl ester can contain C as herein defined₆To C₁₀Aryl, which can be unsubstituted Or the C that is selected from halogen ,-OH, is unsubstituted₁To C₂Alkoxyl and-NH₂1,2 or 3 substituent groups replaced.It is preferred that Ground, the aryl ester contain 1 or 2, the preferably benzene replaced by 1 substituent group unsubstituted or that be selected from halogen and-OH Base.The example of preferred ester includes methyl ester, ethyl ester, propyl ester, isopropyl ester, butyl ester, isobutyl ester, Octyl Nitrite, hydroxyl ethyl ester, hydroxypropyl The ester of ester, hydroxyl ethyl ester, phenyl ester and benzyl ester, such as methacrylic acid.

The polyhydric alcohol is not particularly limited, for example, can be aliphatic, alicyclic or aromatic polyol.Generally, polyhydric alcohol It is polyether polyol or PEPA, preferred, polyethers polyhydric alcohol.In other cases, the polyhydric alcohol is straight or branched alkane Polylol, which may, for example, be Base；More generally 2,3 or 4 alcohol radicals, such as 2 alcohol radicals) C₁To C₁₀Alkyl.More generally, alkyl polyols can contain C₂To C₆Alkane Base, such as C₂、C₃Or C₄Alkyl.The example of suitable polyhydric alcohol includes ethylene glycol, diethylene glycol, 2,2'-ethylenedioxybis(ethanol)., 1,3- Propylene Glycol, ring Hexane dimethanol, 4- butanediols, glycerol, tetramethylolmethane, Sorbitol and trimethylolpropane.

Water soluble acrylic acid dispersion can comprising 20wt% to 60wt% solid, more preferably 30wt% to 50wt%, still more It is preferred that 35wt% to 45wt%, e.g., from about 40 weight %.Generally, acrylic acid dispersion 23 DEG C viscosity be 100mPa.s extremely 2500mPa.s, more generally 100mPa.s to 1000mPa.s, such as 100mPa.s to 500mPa.s.Being total in acrylic acid dispersion Polymers preferably has the minimum film formation temperature (MFFT) less than or equal to 30 DEG C.Generally, the Weight-average molecular of acrylic copolymer Amount is for about 10,000 to about 3,000,000, preferably from about 10,000 to about 200,000 and most preferably from about 20,000 to 120,000. Generally, for about 0 DEG C to 140 DEG C of the glass transition temperature of acrylic copolymer, more typically from about 20 DEG C to 120 DEG C, most commonly about 40 DEG C to 80 DEG C.Generally, tensile strength of the acrylic copolymer in fracture is for about 20MPa to about 70MPa, more typically about 40MPa to about 60MPa.

The present invention compositionss comprising 1wt% to 10wt%, preferred 1wt% to 7wt%, more preferably 2wt% to 5wt%, The water soluble acrylic acid dispersion of e.g., from about 3wt% or about 4 weight %.

The compositionss of the present invention can include stabilizer.The stabilizer can preferably act as the hydrophilic chain extension of polyurethane Agent.When stabilizer is present in the compositionss of the present invention, the compositionss generally comprise 0.1wt% to 5wt%, are preferably The stabilizer of 0.1wt% to 2wt%, more preferably 0.2wt% to 1wt%.

Typical stabilizer includes amine (such as primary amine, the secondary amine and tertiary amine) stabilizer for replacing.Preferably, amine stabiliser is Formula (II) compound or its salt.

In formula (I), R¹And R²Can be with identical or different, which is independently selected from-OH, the C being substituted₁To C₆Alkyl and Jing Substituted C₂To C₆Thiazolinyl, the group R being wherein substituted¹Or R²By-OH replace and be optionally selected from halogen ,-OH, without Substituted C₁To C₂Alkoxyl and-NH₂1,2 or 3 substituent groups be further substituted with.Preferably, the group R being substituted¹Or R²By- OH replaces and is optionally selected from halogen and 1 or 2 substituent group of-OH is further substituted with.It is highly preferred that the group being substituted R¹Or R²It is further substituted with by 1 substituent group that-OH replaces and be optionally selected from halogen and-OH.Most preferably, it is substituted Group R¹Or R²Replaced but be not further substituted by-OH.

In formula (I), R³Selected from R¹And H.In order to avoid query, work as R³For R¹, each R¹Can be with identical or different.

Preferably, R¹、R²And R³It is each independently-C_nH_2nOH, wherein n are 1 to 3 integer.Most preferably, each R is CH₂CH₂OH so that stabilizer is triethanolamine or its salt.

The compositionss of the present invention can include one or more rheological thickeners.The viscosity of rheological thickeners control product is caused The product has good mobility without sagging (sagging)；Improve brushing, traction coating and other properties of combination； So that the coloring paste of different proportion, effect pigment and other materials are evenly distributed in compositionss；And it is beneficial to combination The bin stability of thing, such as by preventing its cambium layer or precipitation.Generally, compositionss of the invention can include more than one stream Become thickening agent, particularly when the compositionss of the present invention also include coloring agent or effect pigment.

Any suitable rheological thickeners or modifying agent can be used.Rheology modifier includes high-molecular weight compounds, example As cellulose or cellulose derivative [for example, hypromellose (hydroxypropyl methyl cellulose), hydroxyethylmethyl-cellulose and Carboxymethyl cellulose]；Polyvinyl alcohol；Polyethylene Glycol (PEG)；Polyacrylic acid；Wax, such as Cera Flava, candelilla wax and babassu Wax；Natural gum, such as guar gum, xanthan gum, locust bean gum and arabic gum；Gelatin；Hydrocolloid sugar such as carrageenin, side chain Starch, Rhizoma amorphophalli and alginate；Protein such as casein and collagen protein；Organo-silicon compound；Mineral thickener such as dioxy SiClx, bentonite and aluminium-magnesium silicate and the polyurethane of association.The polyurethane of association typically can in an aqueous medium with its Itself or the amphipathic polymer reversibly associated with other molecules.Which usually contains at least one hydrophilic area or group and at least one Individual hydrophobic region or group.For example, the polyurethane of association is typically non-ionic copolymer, and which includes actually general Polyethylene oxide The hydrophilic sequence changed and both the hydrophobic sequences that can be single aliphatic chain and/or cyclic aliphatic and/or chains of aromatic.Associate Polyurethane is widely available.For example, proprietary product includes that SER AD FXlOlO, SER AD FX1035 and SER AD 1070 (come From Servo Delden), Rheolate 255, Rheolate 278 and Rheolate 244 (being all from Rheox), ACULYN 46th, DW 1206F, DW 1206J, Acrysol RM 184 and ACRYSOL 44 (being all from Rohm＆Haas), DeuRheo WT- 204 or WT-202 (the two is all from Elementis) and Borchigel LW 44 (Borchers) and its mixture.Preferably, Thickening agent is the polyurethane of cellulose derivative, polyvinyl alcohol or association.It is highly preferred that thickening agent is hydroxypropyl methyl fiber The polyurethane of element, polyvinyl alcohol or association, which can be such as Elementis DeuRheo WT-204 or Rheolate 255.

When there is one or more rheology modifier in the compositionss of the present invention, the total amount of all of rheology modifier is led to The 0.1wt% to 20wt% of compositionss accounted for often, preferably 0.5wt% to 15wt%, more preferably 1wt% to 10wt%, for example 1.1wt% to 9wt%.When there is more than one rheology modifier in the compositionss, every kind of rheology modifier can be with phase Same or different amount is present, and in wherein described compositionss, the total amount of rheology modifier is as described herein.For example, the compositionss can DeuRheo WT-204 comprising 0.1wt% to 5wt%, such as 0.1wt% to 2wt%；0.1wt% to 5wt%, such as The polyvinyl alcohol of 0.5wt% to 2wt%；With the hydroxypropyl methyl fiber of 0.1wt% to 10wt%, such as 0.5wt% to 5wt% Element.

The compositionss of the present invention can include one or more wetting agent and/or sedimentation agent.Moistening and sedimentation agent cause drying Film layer can keep outside and the richness of its gloss so that film layer is bright, smooth and smooth.When the surface of base material is hydrophobic When, can especially use wetting agent.For example, the surface of people's finger/toenail is generally coated with natural oil, so being used for coating so Base material compositionss in, it is necessary to select with stronger wetting characteristicss one or more wetting agent.

When the compositionss of the present invention include one or more wetting agent, anion or the organic surface of nonionic is usually used Activating agent.Anion surfactant include the ammonium of lauryl ether sulfate alkylates and lauryl sulfate alkylates or Sodium salt, stearate, taurate, isethionate, alkene solfonates, sulfosuccinate and Hamposyl L salt Deng.Nonionic surfactant includes polyoxyethylene glycol (PEG) alkyl ether, polyoxypropylene glycol alkyl ether, glucoside alkyl ether Such as decyl glucoside and lauryl glucoside, glyceryl laurate ester, polysorbate, coconut oleoyl amine list or diethanolamine, pool Luo Shamu etc..The mixture of anion surfactant and nonionic surfactant, such as DAPRO W-77 can also be used (being produced by Elementis).It is also possible to use polyether-modified organic silica, such as polyether siloxane copolymer, for example Tego Wet250, Tego Wet 270 and Tego Twin 4100 (being produced by Degussa), Additol VXW-6503 (Cytec), EFKA-3580 (being produced by EFKA).Preferably, using laureth sulfate alkylates or lauryl sulfate alkane The ammonium or sodium salt of glycolylate, polyoxyethylene glycol alkyl ether or polyether-modified organic silica.

When there is one or more wetting agent in the compositionss of the present invention, the total amount of whole wetting agents generally accounts for described group The 0.01wt% to 10wt% of compound, preferably 0.1wt% to 5wt%, more preferably 0.2wt% to 2wt%, such as 0.3wt% are extremely 1.5wt%.When there is more than one wetting agent in the compositionss, every kind of wetting agent can be deposited with identical or different amount Wherein, in the compositionss, the total amount of wetting agent is as described herein.For example, the compositionss can be comprising 0.05wt% extremely The lauryl ether alkyl sodium sulfate of 2wt%, such as 0.1wt% to 0.5wt% and 0.1wt% to 2wt%, such as 0.2wt% are extremely The EFKA-3580 of 1wt%.

The compositionss of the present invention can include one or more defoamer.In some cases, compositionss of the invention can be with With higher viscosity, in the case, the bubble for being difficult to remove residual during preparation process as described herein may be shown Foam.The bubble remained in compositionss is non-desired, because the presence of which affects the smooth administration of product and will combine Thing causes facing heterogeneous when being administered to base material.Typical defoamer includes Silicone antifoam, such as silicone oil, such as poly- two Methylsiloxane (PDMS) and hexamethyl disiloxane；It is preferred that PDMS.Can be using the defoamer such as CF-500 containing silicone (Felixichem), Afcona 2501, Afcona 2502, Afcona 2524 (being produced by AFCONA Chemicals), Antifoam 204 (Sigma), from the Silofoam products and the Foamdoctor from PennWhite of Wacker.It is preferred that Water base defoamer.

When there is one or more defoamer in the compositionss of the present invention, the total amount of whole defoamer generally accounts for described group The 0.01wt% to 0.5wt% of compound, preferably 0.02wt% to 0.2wt%, more preferably 0.04wt% to 0.15wt%, for example 0.05wt% to 0.1wt%.When there is more than one defoamer in the compositionss, every kind of anti-foam agent can be with identical or not Same amount is present, and in wherein described compositionss, the total amount of defoamer is as described herein.For example, the compositionss can be included The AFCONA-2524 of 0.05wt% to 0.1wt%.

The compositionss of the present invention can include one or more coloring agent or effect pigment.Coloring agent or effect pigment can be added The outward appearance after base material is administered to change compositionss, so as to change the outward appearance of base material.Can use any suitable coloring agent or Effect pigment.Suitable coloring agent is described in " International Cosmetic Ingredient Dictionary and In Handbook (2014Edition) ", and including titanium dioxide (CI77891), Zinc Oxide, ferrum oxide, chromium oxide, ultramarine, Barba hispanica, carbon black, CI12490, CI13015, CI27755, CI69800 etc..Suitable effect pigment includes flash of light and pearlescent effect Pigment.Preferred effect pigment includes those containing ground mica, powdery boron, bismuth oxychloride, polyethylene terephthalate etc..

When there is one or more coloring agent or effect pigment in the compositionss of the present invention, all coloring agent or effect face The total amount of material generally accounts for the 0.01wt% to 40wt% of the compositionss, more preferably preferably 0.05wt% to 35wt%, 0.1wt% To 30wt%.Generally, coloring agent will account for the 0.01wt% to 10wt% of total composition, such as 0.05wt% extremely if present 8wt%, such as 0.1wt% to 5wt% of described compositionss.Generally, effect pigment will account for total composition if present 0.5wt% to 40wt%, such as 1wt% to 30wt%, such as 2wt% to 25wt% of total composition.Generally, therefore, work as institute When there is both one or more coloring agent and one or more effect pigment in stating compositionss, compared with coloring agent, described group Compound includes more effect pigments (by weight percentage).For example, what the compositionss can be comprising 0.1wt% to 5wt% The effect pigment of coloring agent and 2wt% to 25wt%, wherein coloring agent and effect pigment are selected from those described herein.

The compositionss of the present invention can include one or more bitters.The compositionss comprising bitters of the present invention can be to meeting with Especially there is use value by the individuality of mandatory or habitual onychophagy (stinging finger/toenail).Suitable bitters include benzoic acid Denatonium, denatonium sugar, sucrose octaacetate, Quercetin and guassin.Preferably, bitters be denatonium benzoate, that Ammonium sugar or sucrose octaacetate, and most preferably, bitters are denatonium benzoates.Bitters are generally with low-down concentration Use, such as less than 1000ppm, more typically less than 100ppm, still more typically less than 10ppm, such as less than 1ppm.

The compositionss of the present invention can be comprising the material for promoting finger/toenail to grow.Suitable material includes cyclosporin, The deacetylated shell of such as cyclosporin A and its derivant, chitosan such as hydroxyalkyl chitosan and carboxyalkyl Many carbohydrates and their derivatives.

The present invention compositionss optionally include other additives well known by persons skilled in the art, such as spreading agent, Dispersant, preservative, ultraviolet (UV) resistant agent, wetting agent etc..

The compositionss of the present invention include the water of surplus.The balance of amount for making total composition reach water needed for 100wt%.The water Can distill or by other method purification and/or deionization (such as by reverse osmosiss) to final resistivity preferably more than or Equal to about 0.01M Ω cm, more preferably greater than or equal to about 0.01M Ω cm, still more preferably greater than or equal to about 0.5M Ω cm It is greater than or equal to about 1M Ω cm.For avoiding query, once having included every other component in compositionss, the surplus of water is i.e. true It is fixed, and therefore the compositionss comprising specific components and excess water are not excluded for compositionss also containing other components.

The total solids content of the present composition is usually 10wt% to 70wt%, more typically 20wt% to 60wt%, 30wt% to 50wt% is more typically still.

Therefore, preferred compositionss of the invention are included：

The aqueous dispersion of the polyurethane -34 or polyurethane -35 of 25wt% to 40wt%, wherein described dispersion are included The solid of 30wt% to 50wt%；

The water soluble acrylic acid dispersion of 1wt% to 7wt%, which includes the solid of 30wt% to 50wt%, and includes The self-cross-linking copolymers of following material：

() methacrylic acid, acrylic acid or .beta.-methylacrylic acid or its methyl ester, ethyl ester, propyl ester, isopropyl ester, butyl ester, isobutyl ester, second The own ester of base, hydroxyl ethyl ester, hydroxypropyl acrylate, hydroxyl ethyl ester, phenyl ester or benzyl ester；With

(ii) ethylene glycol, diethylene glycol, 2,2'-ethylenedioxybis(ethanol)., 1,3- Propylene Glycol, cyclohexanedimethanol, 4- butanediols, glycerol, Ji Wusi Alcohol, Sorbitol or trimethylolpropane.

And optionally also comprising any or whole in following：

Formula (II) compound or its salt of 0.1wt% to 2wt%, wherein, R¹、R²And R³It is each independently and is substituted C₁To C₆Alkyl or the C being substituted₂To C₆Thiazolinyl, the group R being wherein substituted¹、R²Or R³Replaced and optionally entered by-OH One step is selected from halogen and 1 substituent group of-OH is replaced.

0.5wt% to 15wt% selected from cellulose, cellulose derivative, polyvinyl alcohol, Polyethylene Glycol (PEG), poly- One or more rheology modifier of acrylic acid and the polyurethane for associating；

Amount to one or more wetting agent and/or sedimentation agent, the wetting agent and/or the sedimentation of 0.1wt% to 5wt% Agent selected from laureth sulfate alkylates ammonium salt or sodium salt, the sodium salt of lauryl sulfate alkylates or ammonium salt, Stearate, taurate, isethionate, alkene solfonates, sulfosuccinate or Hamposyl L salt；Polyoxy Ethylene glycol alkyl ether；Polyoxypropylene glycol alkyl ether；Glucosides alkyl ether；Glyceryl laurate ester；Polysorbate；Cocos nucifera oil list or diethyl Hydramine；Poloxamer；Polyether-modified organic silica；And the mixture of anion and nonionic surfactant；

The silicone antifoams agent of 0.2wt% to 0.2wt%；With

The effect pigment of the coloring agent and/or 1wt% to 30wt% of 0.01wt% to 10wt%；

Balance of water.

The preferred compositionss of the present invention are included：

The aqueous dispersion of the polyurethane -35 of 30wt% to 35wt%, wherein described dispersion include 35wt% extremely The solid of 45wt%；

The water soluble acrylic acid dispersion of 2wt% to 5wt%, which includes the solid of 35wt% to 45wt%, and includes The self-cross-linking copolymers of following material：

() methacrylic acid or its methyl ester, ethyl ester, propyl ester, isopropyl ester, butyl ester, isobutyl ester, Octyl Nitrite, hydroxyl ethyl ester, hydroxyl Propyl ester, hydroxyl ethyl ester, phenyl ester or benzyl ester；With

(ii) polyhydric alcohol, which is selected from ethylene glycol, diethylene glycol, 2,2'-ethylenedioxybis(ethanol)., 1,3-PD, cyclohexanedimethanol, 4- fourths two Alcohol, glycerol, tetramethylolmethane, Sorbitol and trimethylolpropane；

Amount to one or more formula II compound or its salt of 0.1wt% to 2wt%, wherein R¹、R²And R³Each solely It is on the spot-C_nH_2nOH, wherein n are 1 to 3 integer.

Amount to 0.5wt% to 15wt% selected from cellulose or the poly- ammonia of cellulose derivative, polyvinyl alcohol and association One or more rheology modifier of ester；

Amount to one or more wetting agent and/or sedimentation agent, the wetting agent and/or the sedimentation of 0.2wt% to 2wt% Agent is selected from the ammonium salt or sodium salt of laureth sulfate alkylates or lauryl sulfate alkylates；Polyethylene oxide two Alcohol alkyl ether and polyether-modified organic silica；With

Amount to 0.02wt% to 0.2wt% selected from polydimethylsiloxane, hexamethyl disiloxane and water base silicone One or more defoamer of defoamer.

And optionally also include the effect pigment of the coloring agent and/or 1wt% to 30wt% of 0.05wt% to 8wt%；

And the water of surplus.

The most preferred compositionss of the present invention are included：

The triethanolamine of 0.2wt% to 1wt% or its salt；

The hydroxypropyl methylcellulose of 0.5wt% to 5wt%, the polyvinyl alcohol of 0.5wt% to 2wt% and 0.1wt% are extremely The polyurethane of the association of 2wt%；

The laureth alkyl sodium sulfate and 0.2wt% to 1wt% of 0.1wt% to 0.5wt% it is polyether-modified Organic silica；With

The water base silicone antifoams agent of 0.05wt% to 0.1wt%.

And optionally also include the effect pigment of the coloring agent and/or 2wt% to 25wt% of 0.1wt% to 5wt%；

And the deionized water of surplus.

Conventional water base finger/toenail varnish can by simply at room temperature blending ingredients with obtain uniform compositionss come Produce.It is possible to produce the compositionss of the present invention in the same way.

However, the inventors discovered that, favourable result is produced from Body and water soluble acrylic acid dispersion.Preferably, applying vacuum can be come by using vacuum pump such as rotating vane or vortex pump. Any suitable pump can be used.Preferably, the pressure in reaction vessel be less than 600 supports, such as less than 200 supports, more preferably Less than 100 supports, such as less than such as less than 50 supports, 20 supports.Temperature is increased to into about 50 DEG C to about 70 DEG C, e.g., from about 60 DEG C.Will Said composition is kept 96 hours or the longer time at such elevated temperature in vacuum, such as 100 hours to 150 hours, for example About 120 hours.

If it exists, then while being for example stirred by mechanical agitator or magnetic stirring apparatuss to described Add whole stabilizers, rheological agent, wetting agent and sedimentation agent and defoamer in compositionss.Once have been obtained for uniform molten Liquid, you can one or more coloring agent of addition and/or one or more effect pigment (if present).Generally for example becoming Solid constituent is ground to form fine powder in fast roller mill, and (typical particle diameter is less than 1000 μm, more preferably less than 500 μm, such as less than 100 μm, such as less than 50 μm).

Then mixture is stirred for until obtaining homogeneous solution again.

Preferably, the homogeneous mixture is subsequently heated to about 40 DEG C to about 50 DEG C, e.g., from about 45 DEG C.By compositionss at this Kept for 5 to 8 hours in a little temperature ranges, while being for example timed using mechanical agitator or magnetic stirring apparatuss or persistently being stirred Mix.

Method described herein may also include filtration step, it is one or more other heating and/or cooling step and/or To compositionss applying vacuum.In packaging or finally using before the compositionss, using the denseness of deionized water regulation composition, Viscosity and color.

Examples below is explained explanation to the present invention, and limits the present invention never in any form.

Embodiment

Method

Solid percentage ratio in dispersions can be measured by any suitable method.It is, for example possible to use such as this Gravimetric method described in text is determining percentage of solids.The quality of dispersion samples is measured in container known to quality.Then will The sample is heated above 100 DEG C such as 150 DEG C, is kept for about 2 hours.Then the sample is cooled down in exsiccator, to prevent Again moisture absorption before weighing.Then, percentage ratio of the solid in dispersion samples may be calculated

The viscosity of dispersion can be measured by any suitable method.It is, for example possible to use Brookfield viscometer is for example Model RVF or RVDVII is determining viscosity.Select suitable main shaft, the spindle #3 for for example being rotated with 20rpm, and by dispersion sample Product are applied to viscometer.The viscosity of dispersion is determined according to the description of manufacturer；For example, the viscosity generally in terms of mPa.s Often directly read from viscometer.

Glass transition temperature can be measured by any suitable method.It is for instance possible to use means of differential scanning calorimetry Meter (DSC).Any suitable DSC instrument can be used, and generally be arranged with its standard.For example, 204 instrument of NETZSCH DSC can be with 10 DEG C/min of the rate of heat addition is used with the example weight of about 10mg in -100 DEG C to+250 DEG C temperature ranges.

Elongation factor and tensile strength can be measured by any suitable method.For example, can use and stablize micro-system matter Ground analyser (TA.XTplus.Winopal Forschungsbedarf GmbH) cupping machine in its standard conditions (for example 54% relative humidity and 23 DEG C) under operation determining the two parameters.

Embodiment 1

Prepare aqueous, polyurethane -35, acrylic acid, hydroxypropyl methyl cellulose, polyvinyl alcohol, triethanolamine, Laurel ether 12 The compositionss of sodium sulfate, titanium dioxide, Muscovitum, CI 77891 and CI 12490.Said composition is pale pink, has slight pearly-lustre Effect.

The said composition of monolayer is applied to into the fingernail of four female subjects of the age between 25 years old to 50 years old.Measurement Said composition drying is transferred to the time required for the degree (" touch drying ") on another surface to after not observing contact.So After apply second coating, assess the smoothness and glossiness of coating coverage rate, evaluating score is：Smooth and bloom [+]；Somewhat light Sliding and/or low in glossiness [Δ]；Or coarse and low in glossiness [X].

By peeling off from fingernail removing compositionss after 10 minutes.According to the easness that following standard evaluation is removed：Easily go Remove, film keeps complete or substantially complete [+]；It is difficult to remove, causes film division [Δ]；Or [X] can not possibly be peeled off.Average result shows In table 1.

Comparative example 1

The Conventional solvents base finger/toenail varnish of similar opacity (shade) is applied to experimenter same as Example 1 (" Stay Perfect ", No. 7, available from Boots PLC).The parameter measured in determining embodiment 1.As a result it is shown in Table 1.

Table 1

	Embodiment 1	Comparative example 1
			Abnormal smells from the patient	It is negligible	Strong solvent abnormal smells from the patient
It is dried required time/minute	2-5	5-15
			Smoothness/gloss (2 to 3 coatings)	+	+
By peeling off the easness for removing	+	X

The compositionss of the present invention have the significant advantage of negligible abnormal smells from the patient.The outward appearance of produced film with contrast The presentation quality produced by conventional finger/toenail varnish tested in example 1 quite, is dried in suitable or faster time range. Easily by peeling off removal, this is impossible for conventional finger/toenail varnish to the film.

Claims

1. a kind of peelable cosmetic composition, which includes：

The aqueous pu dispersions of 20wt% to 50wt%；With

The water soluble acrylic acid dispersion of 1wt% to 10wt%.

2. peelable cosmetic composition according to claim 1, wherein described aqueous pu dispersions include poly- ammonia Ester, it is characterised in that：

- glass transition temperature is 30 DEG C or lower；

- in fracture, the elongation factor is 500% or higher；

- in 100% elongation, tensile strength is 1 to 10MPa；And/or

- tensile strength at break be 25 to 75MPa.

3. according to peelable cosmetic composition in any one of the preceding claims wherein, wherein described aqueous polyurethane dispersion Solid of the body comprising 20wt% to 60wt%.

4. according to peelable cosmetic composition in any one of the preceding claims wherein, wherein described aqueous polyurethane dispersion Body is 100 to 2500mPa.s in 23 DEG C of viscosity.

5. according to peelable cosmetic composition in any one of the preceding claims wherein, wherein described aqueous polyurethane dispersion Polyurethane of the body comprising the product containing following material：(i) diisothio-cyanate, its be selected from isophorone diisocyanate, Isocyanatometyl ethylo benzene, 5- isocyanate group -1- (isocyanatomethyl) -1,3,3- trimethyl-cyclohexanes, a tetramethylene two Toluene di-isocyanate(TDI), methylene biscyclohexyl diisocyanate, hexamethylene diisocyanate, two isocyanide of dicyclohexyl methyl hydride Acid esters and toluene di-isocyanate(TDI)；() polyhydric alcohol, which is selected from hexanediol, neopentyl glycol, Propylene Glycol, ethylene glycol, dihydroxymethyl Propanoic acid, trimethylolpropane, polytetramethylene ether diol, polytetramethylene glycol, oxa- ring in heptan -2- ketone/2,2- dimethyl -1,3- the third two Alcohol copolymer, 1,4- butanediols, hexanediol and polyethylene-poly- (tetramethylene) glycol；() dicarboxylic acids, which is selected from adipic acid And M-phthalic acid.

6. according to peelable cosmetic composition in any one of the preceding claims wherein, wherein described dispersions of polyurethanes bag Containing polyurethane -34 or polyurethane -35.

7. according to peelable cosmetic composition in any one of the preceding claims wherein, wherein described water soluble acrylic acid dispersion Copolymer of the body comprising following material：

(i) one or more acidiferous monomer, or its C₆To C₁₀Aryl ester or C₁To C₁₀Arrcostab or its salt；It is wherein described single containing acid Body includes alpha-beta ethylene type carboxylic acid；With

(ii) one or more polyhydric alcohol, which is selected from polyether polyol, PEPA and containing two or more alcohol (- OH) The straight or branched C of group₁To C₁₀Alkyl polyols.

8. according to peelable cosmetic composition in any one of the preceding claims wherein, wherein described water soluble acrylic acid dispersion Copolymer of the body comprising following material：

() acrylic acid, methacrylic acid .beta.-methylacrylic acid, maleic acid, itaconic acid, glutaconate or mesaconic acid；Or derivatives thereof, its The C that derived thing is selected from halogen, is unsubstituted₁To C₃Alkyl, the C being unsubstituted₁To C₂Alkoxyl and-NH₂One or two Individual substituent group is replaced；Or

The C of acrylic acid, methacrylic acid .beta.-methylacrylic acid, maleic acid, itaconic acid, glutaconate or mesaconic acid₁To C₁₀Arrcostab；Or Its derivant；The C that wherein described alkyl is unsubstituted, is perfluorinated or is selected from halogen ,-OH, be unsubstituted₁To C₂Alkoxyl With-NH₂1,2 or 3 substituent groups replaced；Or

The C of acrylic acid, methacrylic acid .beta.-methylacrylic acid, maleic acid, itaconic acid, glutaconate or mesaconic acid₆To C₁₀Aryl ester；Or Its derivant；Wherein described aryl is unsubstituted or the C that is selected from halogen ,-OH, is unsubstituted₁To C₂Alkoxyl and-NH₂'s 1st, 2 or 3 substituent groups are replaced；With

(ii) polyether polyol, PEPA or the straight or branched C containing two or more alcohol groups₁To C₁₀Alkyl Polyhydric alcohol.

9. according to peelable cosmetic composition in any one of the preceding claims wherein, wherein described water soluble acrylic acid dispersion Copolymer of the body comprising following material：

() methacrylic acid, acrylic acid or .beta.-methylacrylic acid or its C₁To C₁₀Arrcostab or C₆To C₁₀Aryl ester, wherein described alkyl portion Divide C that is unsubstituted, being perfluorinated or be selected from halogen ,-OH, be unsubstituted₁To C₂Alkoxyl and-NH₂1,2 or 3 take Replaced for base；Or wherein described aryl moiety is unsubstituted or the C that is selected from halogen ,-OH, is unsubstituted₁To C₂Alcoxyl Base and-NH₂1,2 or 3 substituent groups replaced；With

(ii) polyether polyol or the C containing 2,3,4,5 or 6 alcohol groups₂To C₆Alkyl polyols.

10. according to peelable cosmetic composition in any one of the preceding claims wherein, wherein described water soluble acrylic acid point The acrylic copolymer in a prose style free from parallelism is characterized by：

- less than or equal to 30 DEG C of minimum film formation temperature (MFFT)；

The weight average molecular weight of-about 10,000 to about 3,000,000；

And/or

- about 0 DEG C to 140 DEG C of glass transition temperature.

11. according to peelable cosmetic composition in any one of the preceding claims wherein, wherein described water soluble acrylic acid point Solid of the prose style free from parallelism comprising 20wt% to 60wt%.

12. according to peelable cosmetic composition in any one of the preceding claims wherein, wherein described water soluble acrylic acid point The viscosity of a prose style free from parallelism is 100 to 2500mPa.s.

13. according to peelable cosmetic composition in any one of the preceding claims wherein, and which includes：

The aqueous dispersion of the polyurethane -34 or polyurethane -35 of -25wt% to 40wt%, wherein described dispersion are included The solid of 30wt% to 50wt%；With

The water soluble acrylic acid dispersion of -1wt% to 7wt%, which includes the solid of 30wt% to 50wt%, and includes following thing The self-cross-linking copolymers of matter：

() methacrylic acid, acrylic acid or .beta.-methylacrylic acid or its methyl ester, ethyl ester, propyl ester, isopropyl ester, butyl ester, isobutyl ester, ethyl hexyl Ester, hydroxyl ethyl ester, hydroxypropyl acrylate, hydroxyl ethyl ester, phenyl ester or benzyl ester；With

(ii) ethylene glycol, diethylene glycol, 2,2'-ethylenedioxybis(ethanol)., 1,3- Propylene Glycol, cyclohexanedimethanol, 4- butanediols, glycerol, tetramethylolmethane, Sorbitol or trimethylolpropane.

14. according to peelable cosmetic composition in any one of the preceding claims wherein, and which includes total 0.1wt% extremely One or more stabilizer of 5wt%.

15. according to peelable cosmetic composition in any one of the preceding claims wherein, and which includes total 0.1wt% extremely One or more rheology modifier of 20wt%.

16. according to peelable cosmetic composition in any one of the preceding claims wherein, and which includes total 0.01wt% extremely One or more wetting agent of 10wt% and/or sedimentation agent.

17. according to peelable cosmetic composition in any one of the preceding claims wherein, and which includes total 0.01wt% extremely One or more defoamer of 0.5wt%.

18. according to peelable cosmetic composition in any one of the preceding claims wherein, and which includes total 0.01wt% extremely One or more coloring agent of 40wt% or effect pigment.

19. according to peelable cosmetic composition in any one of the preceding claims wherein, and which includes 10wt% to 70wt% Solid.

20. according to peelable cosmetic composition in any one of the preceding claims wherein, and which includes：

The aqueous dispersion of the polyurethane -35 of -30wt% to 35wt%, wherein described dispersion include 35wt%'s to 45wt% Solid；

The water soluble acrylic acid dispersion of -2wt% to 5wt%, which includes the solid of 35wt% to 45wt%, and includes following thing The self-cross-linking copolymers of matter：

() methacrylic acid or its methyl ester, ethyl ester, propyl ester, isopropyl ester, butyl ester, isobutyl ester, Octyl Nitrite, hydroxyl ethyl ester, hydroxypropyl Ester, hydroxyl ethyl ester, phenyl ester or benzyl ester；With

(ii) polyhydric alcohol, which is selected from ethylene glycol, diethylene glycol, 2,2'-ethylenedioxybis(ethanol)., 1,3-PD, cyclohexanedimethanol, 4- butanediols, sweet Oil, tetramethylolmethane, Sorbitol and trimethylolpropane；

One or more formula II compound or its salt of-total 0.1wt% to 2wt%, wherein R¹、R²And R³Independently of one another For-C_nH_2nOH, wherein n are 1 to 3 integer；

- amount to 0.5wt% to 15wt% selected from the one of cellulose or the polyurethane of cellulose derivative, polyvinyl alcohol and association Plant or various rheology modifiers；

One or more wetting agent and/or sedimentation agent of-total 0.2wt% to 2wt%, which is selected from laureth sulfate alkane The ammonium salt or sodium salt of glycolylate or lauryl sulfate alkylates；Polyoxyethylene glycol alkyl ether and polyether-modified organic Silicon dioxide；With

- amount to 0.02wt% to 0.2wt% selected from polydimethylsiloxane, hexamethyl disiloxane and water base silicone antifoams agent One or more silicone antifoams agent.

21. according to peelable cosmetic composition in any one of the preceding claims wherein, and which includes：

The triethanolamine of -0.2wt% to 1wt% or its salt；

The hydroxypropyl methylcellulose of -0.5wt% to 5wt%, the polyvinyl alcohol of 0.5wt% to 2wt% and 0.1wt% to 2wt% Association polyurethane；

Polyether-modified organic two of the laureth alkyl sodium sulfate and 0.2wt% to 1wt% of -0.1wt% to 0.5wt% Silicon oxide；

The water base silicone antifoams agent of -0.05wt% to 0.1wt%.

A kind of 22. methods produced according to peelable compositionss in any one of the preceding claims wherein, which includes：

- divide in aqueous pu dispersions described in heating under vacuum and the water soluble acrylic acid in about 50 DEG C to about 70 DEG C of temperature A prose style free from parallelism at least 96 hours；Then

- optionally add one or more coloring agent and/or one or more effect pigment.

A kind of 23. methods for producing peelable compositionss according to claim 20, which is additionally included in and completes claim After the step of described in 20, the compositionss are heated to about into 40 DEG C to about 50 DEG C, and by the temperature while stirring Maintain 5 to 8 hours.

A kind of 24. peelable finger/toenail varnish, which includes the peelable cosmetic according to any one of claim 1 to 21 Product compositionss or the compositionss obtained comprising the method passed through described in claim 22 or 23.