CN106510656A - Measuring device based on programmable control companding - Google Patents

Measuring device based on programmable control companding Download PDF

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Publication number
CN106510656A
CN106510656A CN201710015056.8A CN201710015056A CN106510656A CN 106510656 A CN106510656 A CN 106510656A CN 201710015056 A CN201710015056 A CN 201710015056A CN 106510656 A CN106510656 A CN 106510656A
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companding
signal
blood vessel
unit
detection
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CN106510656B (en
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韦岗
刘娇蛟
曹燕
马碧云
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South China University of Technology SCUT
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/02007Evaluating blood vessel condition, e.g. elasticity, compliance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6822Neck
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6824Arm or wrist
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
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  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Molecular Biology (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Physiology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Psychiatry (AREA)
  • Signal Processing (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

The invention discloses a vascular condition measuring device based on programmable control companding. The device comprises two flexible detection terminals with ultrasonic transmitting-receiving capacity, a pneumatic companding bag, a control module, a detection module and a speed regulation air pump, wherein the pneumatic companding bag is connected with the control module, the control module is connected with the speed regulation air pump, and the detection module is connected with the control module. Determined pressure is applied to different positions of the companding bag by program control, transmission characteristics of blood vessels at the application positions are changed, the transmission characteristics of the blood vessels between a cardiac muscle and a pulse detection point are identified by active detection and channel inversion for the cardiac muscle and pulse point fluctuation, the transmission characteristics of local blood vessels at the application positions are identified according to the transmission characteristics of the blood vessels before and after pressure application and channel cascade characteristics, and conditions such as elasticity, occlusion and vascular wall thickness of the local blood vessels can be judged by the aid of characteristic extraction and characteristic comparison. The device has the advantages that measuring positions, companding modes and pressure strength can be controlled and the like.

Description

A kind of blood vessel state measurement apparatus based on program control companding
Technical field
The invention mainly relates to blood vessel state detection technique field, and in particular to a kind of blood vessel state based on program control companding Measurement apparatus.
Background technology
Pulse-taking is a kind of exclusive methods for the diagnosis of diseases of the traditional Chinese medical science.Over more than 2000 years, the traditional Chinese medical science gets used to pulse-taking, main with " very little The mouth diagnostic method " understands the prosperity and decline of each zang-fu differentiation QI and blood of whole body, and feeling the pulse is often with three kinds of finger power:Start gently firmly, to touch and press skin For feeling the pulse lightly, entitled " act ";Then in it is isocratic firmly, touch by taking in muscle being, entitled " seeking ";Power is reused again and is touched by muscles and bones be Taking the pulse heavily, entitled " by ".From the point of view of physical essence, wrist portion arterial pulse and its change define pulse wave, and it is heartbeat Formed along arteries and blood flow to periphery spread, therefore the aspect such as its form, intensity, speed and rhythm and pace of moving things for being showed Integrated information reflect many physiology and pathological characters of cardiovascular system of human body.Adopt to press with finger to change during feeling the pulse and connect The blood vessels transport properties of tactile position, are easy to doctor to make accurately judgement to the pulse condition of position of feeling the pulse, and this pulse condition is (including arterial pulse The dynamic depth for manifesting position, the speed of speed, the size of intensity, the rhythm and pace of moving things it is whether uniform etc.) be exactly position pulse wave of feeling the pulse Some attributes, human health status can be judged accordingly.
Although feeling with finger before the centuries and imagination can draw tens kinds of pulse conditions, the information obtained by pulse-taking It is still limited by the sensory faculty of doctor.In order to obtain the beating feature of arteries depths, doctor can be using obtaining again by by the way of , the acquisition of these information depends on maneuver and the experience accumulation of doctor.In order to solve the detection of pulse wave and blood vessel state, I In patent:Blood vessel state detection method and device (publication number based on heart point fluctuation transport properties:CN105286919A) In give measurement blood vessel pulse wave and blood vessel state a kind of method.Said method needs to arrange test point in blood vessel wall, adopts The position of test point is continuously monitored with the transmitting and reception of ultrasound wave and obtain pulse wave, according to the method for signal processing The transport properties and its time-frequency characteristics of blood vessel between test point are obtained.However, on arteries the beating of most of position is not Enough obvious, its measurement result can affect the accuracy of Subsequent vessel state-detection.
In consideration of it, this patent proposes a kind of blood vessel state measuring method based on program control companding and device.The method exists The local location wearing companding bag of human body, applies the pressure for determining by programme-control in companding bag diverse location, and press position There is respective change therewith in the transport properties of place blood vessel, using the arteries and veins of the pulse detection points such as wrist/cervical region (beating is substantially located) Fight ripple, the active detecting of cardiac muscle point fluctuation and the signal processing method such as channel inverting, can be between cardiac muscle and pulse detection point The transport properties of blood vessel are recognized.Then, using the transport properties of blood vessel, pressure characteristic and channel cascaded feature before and after pressure The transport properties of the position local vascular that presses can be identified, by feature extraction and aspect ratio to can be to local vascular Elasticity, blocking, the state such as vessel wall thickness judged.The device has measurement position, companding pattern and the intensity of pressure can The features such as control, can go to control mode of operation (press/not pressing), the output of companding bag diverse location by formula, it is real The automatic measurement of existing local vascular state, can be widely used for the fields such as health monitoring, remote medical examination and auxiliary diagnosis.
The content of the invention
It is an object of the invention to overcome the above-mentioned deficiency of prior art, the present invention proposes a kind of based on program control companding Blood vessel state measurement apparatus, concrete technical scheme are as follows.
A kind of blood vessel state measurement apparatus based on program control companding, which includes two flexibilities with ultrasonic transmission/reception ability Detection terminal, pneumatic companding bag, control module, detection module and speed governing air pump;Wherein pneumatic companding bag is connected with control module Connect, control module is connected with speed governing air pump, and detection module is connected with control module;Flexible detection terminal is responsible for ultrasound detection The driving and transmitting of signal, the reception of ultrasound echo signal and pretreatment, data communication;Pneumatic companding bag is worn on body, Pressure is applied to human body specific part according to the formula for having set;Control module is responsible for the parameter setting of whole device, companding journey The gating of each electromagnetic valve, the Power Control of speed governing air pump and man-machine interaction in formula selection, solenoid valve block;Detection module is responsible for detection The generation of signal, the storage of detection data, the inverting of point fluctuation signal, the identification of blood vessel transport properties, local vascular conduction are special The identification and feature extraction of property, local vascular aspect ratio to and data communication;Speed governing air pump is responsible for pumping into for air, speed governing air pump The speed-regulating signal that exported by control module of motor speed control.
Further, the pneumatic companding bag is made up of integral type air bag cloth bag, inflated hose;Wherein described integral type gas Capsule cloth bag is weaved cotton cloth or vinyl material using soft, is made up of multiple ballonets, between multiple ballonets by sewing or The mode of person's hot sealing separates;Each ballonet connects an inflated hose, and inflated hose is connected to the expansion bag of control module Gating solenoid valve block, constitutes the gas circuit of connection from speed governing air pump to ballonet, the ballonet of corresponding gas circuit connection after formula gating Interior air pressure increases with inflation, so as to press to body local position.
Further, the control module includes companding bag gating solenoid valve block, master controller and man-machine interaction unit;Pressure Expand bag gating solenoid valve block to be made up of multiple solenoid valve blocks, each solenoid valve block contains two electromagnetic valves, one of electromagnetic valve It is connected with speed governing air pump by trachea, another is connected with the external world, by the electromagnetic force of solenoid in current control electromagnetic valve, So that the valve of one of electromagnetic valve is opened, the valve closing of another electromagnetic valve;The electric current of each electromagnetic valve is by main control Device determines, if the electromagnetic valve being connected with speed governing air pump is opened, turns on from the gas circuit of speed governing air pump to ballonet, speed governing air pump Air is pumped into gas circuit, ballonet applies pressure to human body ad-hoc location after heaving;If the electromagnetic valve being connected with the external world is opened, Then turn on from ballonet to extraneous gas circuit, the air in ballonet is discharged by electromagnetic valve;Master controller is according to setting Formula determine companding bag gating solenoid valve block in each electromagnetic valve state and its persistent period, according to formula determine be sent to speed governing The speed-regulating signal of air pump, and then control the stingy intracapsular air pressure of connection;Man-machine interaction unit is responsible for man-machine interaction, for joining The output of number setting, formula setting, the input of control command and error message.
Further, the detection module includes signal generating unit, fluctuation inverting unit, channel identifying unit, sub- letter Road identification unit, feature extraction unit, feature comparing unit, communication unit and data buffer storage unit;The signal generating unit The generation and driving of responsible wideband detection signal, the wideband detection signal deliver to flexible detection terminal by communication unit;It is described Fluctuation inverting unit is responsible for judging to producing the test point position of reflection, structure, using the continuous inspection to test point position Survey can be realized carrying out the point fluctuation of cardiac muscle or pulse the multidimensional detection in time and space;The channel identifying unit utilizes the heart Flesh and the fluctuation of pulse point are recognized to the channel transfer functions that cardiovascular between cardiac muscle and pulse detection point is constituted;The sub- letter Road identification unit is obtained son using the cascade connection between channel by decomposing to the channel transfer functions before and after pressure The transmission characteristic of channel;Time domain, frequency domain spy of the feature extraction unit using signal processing method sub-channel transmission characteristic Levy and be analyzed;The data of time-frequency characteristics and property data base that the feature comparing unit is responsible for sub-channel are compared, And then the state to local vascular judges that correct judged result and feature are stored in property data base;The communication Unit is responsible for the transmission of data and control information between flexible detection terminal and detection module, using wire/wireless communication pattern; The data buffer storage unit is responsible for caching detection signal parameter, ultrasound echo signal data, control parameter.
Further, the speed governing air pump has motor and inflatable mouth, and inflatable mouth is blown into extraneous air in trachea, with The positive pressure increase of the stingy intracapsular air of speed governing air pump connection, applies pressure to present position;Motor speed is by controlling mould The speed-regulating signal control that master controller is sent in block, controls the stingy intracapsular pressure connected by conducting gas circuit by controlled motor rotating speed By force, so control pressure dynamics.
Further, the active measurement of channel transfer functions before and after the detection module is by pressing to local, using letter Road cascades the transmission characteristic that characteristic and signal processing obtain local vascular, carries out spy by feature extraction binding characteristic data base Comparison is levied, local vascular state and its disease are carried out diagnosing, predicted and curative effect tracking;Control module goes to control gas by formula The pressure size of each ballonet and persistent period in bag are expanded in dynamic pressure, so as to control the change of channel transfer functions residing for local vascular Change characteristic, and then realize the automatic measurement of local vascular transmission characteristic.
Further, flexible detection terminal receives the wideband detection signal that detection module is produced, and changes with D/A through amplifying Ultrasound wave is converted into by transmitting probe afterwards and is launched, the ultrasound wave of transmitting produces reflection after running into ventricle wall or blood vessel wall Ultrasonic echo is formed, part ultrasonic echo is received by neighbouring ultrasound probe, the echo-signal of reception turns through amplification, A/D Preserve after changing, and detection module is sent to by communication module.
Further, the fluctuation inverting unit, takes echo analysis and geometry principle to select ventricle wall and blood vessel wall Fixed test point position and its change carry out the time domain/inversion in frequency domain in time and space, obtain the time domain of a fluctuation/frequency domain special Property;
Input signal of the channel identifying unit by the use of cardiac muscle point fluctuation as channel, wrist or cervical region pulse obvious Output signal of the point fluctuation ripple of position as channel, using digital signal processing method between input signal and output signal Blood vessel transfer function by identification;
The feature comparing unit, sub-channel transmission characteristic when/frequency feature compared with the data of property data base It is right, the state of blood vessel to be detected is judged, and is shown in man-machine interaction unit, test position, blood vessel transmission function When/frequency feature, cardiac muscle point fluctuation, the fluctuation of pulse point and patient condition, age etc. be stored in storing sub-units, wherein compares knot Fruit can carry out classification process.
Using the described blood vessel state measuring method based on program control companding, implementing step includes:
1) device parameter is arranged, and arranges the parameter of each unit in detection module, such as wideband detection signal parameter, fluctuation inverting The display parameters of cell parameters, channel identifying cell parameters, communication unit parameter etc. and man-machine interaction unit.
2) automatic detection of equipment state, the state detected by the step include:The connection status of flexible detection terminal, it is soft Property detection terminal and detection module connection status, the connection status of detection module and control module, the connection of communication unit with Presence, the power supply capacity state of flexible detection terminal.
3) generation of wideband detection signal, the wideband detection of the signal generating unit of detection module according to set by step 1 Signal parameter produces wideband detection signal.
4) ultrasonic emitting, flexible detection terminal receive the wideband detection signal that detection module is produced, and this receives signal Ultrasound wave is converted into by transmitting probe after amplifying and D/A is changed and is launched;
5) ultrasonic echo is received, and the ultrasound wave of transmitting is produced after running into ventricle wall or blood vessel wall and reflects to form ultrasonic echo, Part ultrasonic echo is received by neighbouring ultrasound probe, and the echo-signal of reception is preserved through amplifying, after A/D conversions, And detection module is sent to by communication module;
6) inverting of fluctuation signal is put, the detection for taking echo analysis and geometry principle to select ventricle wall and blood vessel wall Point position and its change carry out the time domain/inversion in frequency domain in time and space, obtain a time domain/frequency domain characteristic for fluctuation;
7) channel identifying, by the use of cardiac muscle point fluctuation as the input signal of channel, the pulses such as wrist or cervical region obvious position Output signal of the point fluctuation ripple put as channel, using digital signal processing method between input signal and output signal Blood vessel transfers function by identification;
8) channel identifying after pressing, is inflated to the ballonet selected in pneumatic companding bag according to formula, weight after pressure Multiple step 4) 7), identification is transferred function by the blood vessel after pressure;
9) subchannel identification, using cascade characteristic and the signal processing method of blood vessel, the transmission for obtaining blood vessel at pressure is special Property;
10) feature extraction, by the time domain/frequency-domain analysiss to blood vessel transmission characteristic, obtain it when/frequency feature;
11) aspect ratio pair, sub-channel transmission characteristic when/data of frequency feature and property data base compare, right The state of blood vessel to be detected judged, and shown in man-machine interaction unit, test position, blood vessel transmission function when/ Frequency feature, cardiac muscle point fluctuation, the fluctuation of pulse point and patient condition, age etc. are stored in storing sub-units, and wherein comparison result can To carry out classification process.
Compared with prior art, the present invention has advantages below and technique effect:
(1) present invention utilizes the transmitting-receiving of ultrasound wave in the pulse visibility point active detecting point pulse wave such as wrist/cervical region, Testing result is accurate.
(2) after the present invention is pressed using local, the change of channel characteristics realizes local vascular detection, in body local position Wearing companding bag is put, using change and the cascade characteristic of channel of the characteristic of channel before and after pressure, is played a game using signal processing method The characteristic of channel of portion's blood vessel is recognized, by follow-up feature analysiss and aspect ratio to realizing the measurement of local vascular state.
(3) present invention achieves local vascular measurement it is stylized, by program go control air pump air-blowing quantity, and then control Companding processed wraps intensity, position and the direction of impressed pressure, is capable of achieving the automatic measurement of local vascular state.
(4) present invention to implement personnel requirement it is low, have the advantages that simple structure, it is easy to operate, using safe, according to There is formula be automatically obtained the detection of local vascular state.
Description of the drawings
Fig. 1 is a kind of system architecture diagram of the blood vessel state measurement apparatus based on program control companding in present example;
Fig. 2 is flexible detection terminal structure chart;
Fig. 3 is the overhaul flow chart of the present invention;
Fig. 4 is example sub-channels discrimination method schematic diagram.
Specific embodiment
With reference to embodiment and accompanying drawing the present invention is described in further detail explanation, but embodiments of the present invention Not limited to this.If it is noted that have below, being that those skilled in the art can refer to existing skill Art realize or understand.
Such as Fig. 1, a kind of blood vessel state measurement apparatus based on program control companding, there is ultrasonic transmission/reception ability including two Flexible detection terminal, pneumatic companding bag, control module, detection module and speed governing air pump.Wherein pneumatic companding bag and control module It is connected, control module is connected with speed governing air pump, and detection module is connected with control module.Flexible detection terminal is responsible for ultrasound The driving and transmitting of detection signal, the reception of ultrasound echo signal and pretreatment, data communication;Pneumatic companding bag is worn on body Certain position, according to the formula for having set to human body specific part apply pressure;Control module is responsible for the parameter of whole device Arrange, companding formula is selected, the gating of each electromagnetic valve, the Power Control of speed governing air pump and man-machine interaction in solenoid valve block;Detection Module is responsible for the generation of detection signal, the storage of detection data, the inverting of point fluctuation signal, the identification of blood vessel transport properties, office The identification and feature extraction of portion's blood vessel transport properties, local vascular aspect ratio to and data communication;Speed governing air pump is responsible for air Pump into, its motor speed is controlled by the speed-regulating signal that control module is exported.
The structure of the flexible detection terminal can be using published patent application " based on heart point fluctuation transport properties Blood vessel state detection method and device " (publication number:CN105286919A the structure in), visits including the ultrasound wave of transceiver Head array, transmitting processing unit, reception processing unit and communication unit, they are fixed on flexible PCB.One is received and dispatched wherein The array ultrasonic probe of body is arranged by certain way by multiple ultrasound probes and constitutes array;The transmitting processing unit root The signal received from detection module is amplified according to arrange parameter and D/A conversions, the signal of telecommunication after conversion passes through transmitting probe It is transformed into ultrasonic signal and launches;The reception processing unit is amplified according to the arrange parameter docking collection of letters number, A/D turns Change and data buffer storage;The communication unit is responsible for the transmission of data and control information between flexible detection terminal and detection module, Wire/wireless communication pattern can be adopted.Flexible detection terminal immobilization with adhesive tape is bright close to heart or wrist/cervical region beat pulse It is close to skin on the outside of aobvious place's skin and using couplant.
Based on the blood vessel state measuring method of program control companding, in the local location wearing companding bag of human body, set by formula Determine test position, companding pattern and the intensity of pressure and its change of blood vessel, apply the pressure for determining (containing pressure in blood vessel test position Power size, direction etc.) or change corresponding physical parameter, there is phase in such as temperature etc., then the blood vessel transport properties of the position that presses Should change.Specifically, from heart to wrist/blood flow of the pulse detection point such as cervical region and tremulous pulse can be regarded as a channel, The channel that fluctuation can be with the transmission characteristic of the inverting channel, then before and after pressing is put using the pulse wave and myocardium of pulse detection point Transmission characteristic is different.The blood vessel of pressure position is sub-channels of above-mentioned channel, and the transmission characteristic of this sub-channels is because additional Pressure and change, can be identified with the transmission characteristic of sub-channel using its Variation Features and channel cascaded relation, and then really The characteristic of the feature of sub-channel, i.e. local vascular.By time-frequency characteristic analysis and aspect ratio pair, can also be to local vascular Blocking, thickness, elastic situation are recognized, so as to realize the measurement of local vascular state.
Flexible detection terminal in the blood vessel state measurement apparatus based on program control companding of this example includes transceiver Array ultrasonic probe, transmitting processing unit, reception processing unit and communication unit, they are fixed on flexible PCB, its Structure is as shown in Figure 2.The array ultrasonic probe of the transceiver presses certain way arrangement group by multiple ultrasound probes Into array;The transmitting processing unit is amplified to the signal received from detection module according to arrange parameter and D/A conversions, is turned The signal of telecommunication after changing is transformed into ultrasonic signal by transmitting probe and launches;The reception processing unit is according to arrange parameter The docking collection of letters number is amplified, A/D is changed and data buffer storage;The communication unit be responsible for flexible detection terminal and detection module it Between data and control information transmission, wire/wireless communication pattern can be adopted.
Based on the pneumatic companding bag in the blood vessel state measurement apparatus embodiment of program control companding by integral type air bag cloth bag, fill Gas flexible pipe is constituted.Wherein described integral type air bag cloth bag can be weaved cotton cloth or the material such as vinyl using soft, and it is by multiple ballonets Composition, can be separated by way of sewing or hot sealing each other;Each ballonet connects an inflated hose, this Individual inflated hose is connected to control module, then may be constructed the gas circuit of connection, the gas after formula gating from air pump to ballonet The stingy intracapsular air pressure of road connection increases with inflation, so as to press to body local position.
Companding bag gating electromagnetic valve is included based on the control module in the blood vessel state measurement apparatus embodiment of program control companding Group, master controller and man-machine interaction unit.Wherein, companding bag gating solenoid valve block is made up of multiple solenoid valve blocks, each electromagnetism Valve group contains two electromagnetic valves, and one of electromagnetic valve is connected with speed governing air valve by trachea, and another is connected with the external world, passes through In current control electromagnetic valve, (during energization, the electromagnetic force that solenoid is produced is closure member from valve seat for the electromagnetic force of solenoid Lift, valve is opened;During power-off, electromagnetic force disappears, and spring handle closure member is pressed on valve seat, valve closing) so that one of them The valve of electromagnetic valve is opened, the valve closing of another electromagnetic valve.The electric current of each electromagnetic valve determined by master controller, and if The electromagnetic valve that speed governing air pump is connected is opened, then turn on from the gas circuit of air pump to ballonet, and speed governing air pump pumps into air to gas circuit, little Air bag applies pressure to body local position after heaving;If the electromagnetic valve being connected with the external world is opened, from ballonet to the external world Gas circuit conducting, the air in ballonet can be discharged by electromagnetic valve.Master controller is responsible for the scheduling of different units, protects Card whole system normally run, according to setting formula determine companding bag gating solenoid valve block in each electromagnetic valve state and its hold The continuous time, the speed-regulating signal for being sent to speed governing air pump is determined according to formula, and then controls the stingy intracapsular air pressure of connection;It is man-machine Interactive unit is responsible for man-machine interaction, for the output of parameter setting, formula setting, the input of control command and error message.
Signal generating unit, fluctuation are included based on the detection module in the blood vessel state measurement apparatus embodiment of program control companding Inverting unit, channel identifying unit, subchannel identification unit, feature extraction unit, feature comparing unit, communication unit and data Buffer unit.The signal generating unit is responsible for the generation and driving of wideband detection signal, and the signal is delivered to by communication unit Flexible detection terminal;The fluctuation inverting unit is responsible for judging to producing the test point position of reflection, structure, using to inspection The continuous detecting of point position can carry out the multidimensional detection in time and space to the point fluctuation of cardiac muscle or pulse;The channel is distinguished Knowing unit is carried out to the channel transfer functions that cardiovascular between cardiac muscle and pulse detection point is constituted using cardiac muscle and the fluctuation of pulse point Identification;The subchannel identification unit utilizes the cascade connection between channel, by entering to the channel transfer functions before and after pressure Row decomposes and the transmission characteristic of acquisition subchannel;The feature extraction unit adopts signal processing method sub-channel transmission characteristic Time domain, frequency domain character is analyzed;The feature comparing unit is responsible for the time-frequency characteristics and property data base of sub-channel Data are compared, and then the state to local vascular judges, correct judged result and feature are stored in characteristic In storehouse;The communication unit is responsible for the transmission of data and control information between flexible detection terminal and detection module, and can adopt has Line/wireless communications mode;The data buffer storage unit is responsible for caching detection signal parameter, ultrasound echo signal data, control ginseng Number etc..
Motor and inflatable mouth are had based on the speed governing air pump in the blood vessel state measurement apparatus embodiment of program control companding, this Inflatable mouth is blown into extraneous air in trachea, and the positive pressure increase of the stingy intracapsular air connected with speed governing air pump, to institute Place position applies pressure;Motor speed is controlled by the speed-regulating signal that master controller in control module is sent, and is turned by controlled motor The stingy intracapsular pressure connected by speed control conducting gas circuit is strong, and then controls pressure dynamics.
In embodiment based on the blood vessel state measurement apparatus of program control companding, doctor is using couplant two flexible detections Terminal is close to close on the outside of the skin at heart and wrist pulse, and blend compounds cloth is fixed;Pneumatic companding bag is worn over detected person Arm on, the inflated hose on air bag is connected in control module.After starting measurement apparatus, system carries out parameter setting and shape State detects that the wideband detection signal that control module is produced delivers to each flexible detection terminal by the communication unit of detection module, , through amplifying and D/A conversions in the transmitting processing unit of flexible detection terminal, the signal of telecommunication after conversion is by transmitting for the signal Probe is transformed into ultrasonic signal and launches, and at the test point that cardiac muscle or blood vessel wall are selected produces reflection, and part is reflected Ripple is received by neighbouring ultrasound wave receiving transducer;The ultrasound echo signal of reception is in the reception processing unit of flexible detection terminal It is amplified, A/D is changed and data buffer storage, the data of caching reach detection module through communication unit, and are stored in detection mould The data buffer storage unit of block;Subsequently, detection module starts, and the inverting unit that fluctuates is according to sending and receiving signal to producing the detection reflected Point position, structure are judged, by the continuous detecting to test point position cardiac muscle and the point at wrist pulse can be fluctuated into Row time and the multidimensional detection in space;Channel identifying unit is then fluctuated as input signal with cardiac muscle point, with the point at wrist pulse Fluctuate as cardiovascular output signal, using transmission letter of the method for signal processing to cardiovascular channel between input and output Number H (ejw) recognized;Then, the electric current that air pump gates electromagnetic valve in solenoid valve block is controlled by formula, and then controls electromagnetism Being turned on or off for valve, if turned on from the gas circuit of air pump to ballonet, is passed through by the air that speed governing air pump is pumped into and is somebody's turn to do Gas circuit is blown into ballonet, as a result causes ballonet inner air pressure to increase, applies pressure to human body residing for ballonet, this Pressure size can control speed governing air pump to adjust by speed-regulating signal;Above-mentioned testing process is restarted after pressure, using inspection Transfer function H ' (e of the input and output signal of survey to cardiovascular channel after pressurejw) recognized;Closed using the cascade of channel System and signal processing method, are identified to the transmission characteristic of subchannel at pressure, and then to this sub-channels transmission characteristic Time domain/frequency domain character is analyzed, and the data of these features and property data base are compared and blood vessel to be measured is obtained State parameter, judges the thickness of blood vessel, blocking, elasticity etc..
As a kind of example, as shown in figure 3, being this example subchannel discrimination method schematic diagram
When hypothesis does not press, the cardiac muscle point bounce ripple of detection module side is denoted as X (ejw), point fluctuation at wrist pulse is denoted as Y (ejw).According to the correlation theory of signal processing, the cardiovascular from cardiac muscle to wrist constitutes channel, and this channel is considered as several Sub-channels cascade is formed, it is assumed that this channel is made up of 2 sub-channels cascades, and its transmission function is designated asAnd H (ejw)=H1(ejw)·H2(ejw)。
Controlled to second ballonet pressure, the cardiac muscle point bounce ripple X ' after being pressed after detecting again by formula (ejw) and wrist pulse at point fluctuation Y ' (ejw), now the transmission function of above-mentioned channel can be designated asAnd And H ' (ejw)=H1(ejw)·H2′(ejw)。
If the channel transfer functions after inflation presses to ballonet are denoted as H2′(ejw)=pH2(ejw)+q, wherein Parameter p and q can be fitted by the training of data with existing and data be known, therefore
Simultaneous the two equations, can deriveI.e. son is believed The transmission characteristic in road 2.
The point surge detection that this example is related to, concrete methods of realizing is referring to patent documentation:It is special based on heart point fluctuation conduction Property blood vessel state detection method and device (publication number:CN105286919A), the point bounce of cardiac muscle is obtained by active detecting The point pulse wave of ripple and the test point such as wrist or cervical region pulse, the two is all that the position of blood vessel test point changes over to be formed, Hereinafter referred to as point fluctuation.
As shown in figure 4, being the workflow diagram of the blood vessel state measuring method based on program control companding.
1) device parameter is arranged, and arranges the parameter of each unit in detection module, such as wideband detection signal parameter, fluctuation inverting The display parameters of cell parameters, channel identifying cell parameters, communication unit parameter etc. and man-machine interaction unit.
2) automatic detection of equipment state, the state detected by the step include:The connection status of flexible detection terminal, it is soft Property detection terminal and detection module connection status, the connection status of detection module and control module, the connection of communication unit with Presence, the power supply capacity state of flexible detection terminal.
3) generation of wideband detection signal, the wideband detection of the signal generating unit of detection module according to set by step 1 Signal parameter produces wideband detection signal.
4) ultrasonic emitting, the communication module of flexible detection terminal are responsible for receiving the wideband detection letter that detection module is produced Number, this receives signal and is amplified in transmitting processing unit and D/A conversions, is converted into ultrasound wave by transmitting probe concurrent It is shot out;
5) ultrasonic echo is received, and the ultrasound wave of transmitting is produced after running into ventricle wall or blood vessel wall and reflects to form ultrasonic echo, Part ultrasonic echo is received by neighbouring ultrasound probe, and the echo-signal of reception is amplified in reception processing unit, A/D turns Data buffer storage unit is stored in after changing, and detection module is sent to by communication module;
6) inverting of point fluctuation, the test point position for taking echo analysis and geometry principle to select ventricle wall and blood vessel wall Time domain/the inversion in frequency domain in the time of carrying out and space is put and its changed, a time domain/frequency domain characteristic for fluctuation is obtained;
7) channel identifying, the point by the use of cardiac muscle and wrist pulse fluctuate ripple as the input signal and output signal of channel, Identification is transferred function by the blood vessel between input signal and output signal using digital signal processing method;
8) channel identifying after pressing, is inflated to the ballonet selected in pneumatic companding bag according to formula, weight after pressure Multiple step 4) 7), identification is transferred function by the blood vessel after pressure;
9) subchannel identification, using cascade characteristic and the signal processing method of blood vessel, the transmission for obtaining blood vessel at pressure is special Property;
10) feature extraction, obtains the time-frequency characteristic of subchannel using time domain, frequency-domain analysis method;By transmitting to blood vessel Time domain/the frequency-domain analysiss of characteristic, obtain it when/frequency feature.
11) aspect ratio pair, sub-channel transmission characteristic when/data of frequency feature and property data base compare, right The state of blood vessel to be detected judged, and shown in man-machine interaction unit, test position, blood vessel transmission function when/ Frequency feature, cardiac muscle point fluctuation, the fluctuation of pulse point and patient condition, age etc. are stored in storing sub-units unit, wherein compare knot Fruit is divided into following three class and is processed respectively:
(1) there is disease.Such testing result illustrates that certain section of blood vessel has associated pathology feature, meets characteristic of division storehouse Characteristic information, the characteristic information of blood vessel transmission function will be retained in the feature database of feature comparing unit correspondence disease;
(2) without disease.Such testing result illustrates that certain section of blood vessel does not possess associated pathology feature, directly abandons aspect ratio To the related data in unit;
(3) can hypochondria.Such testing result cannot make a definite diagnosis blood vessel state, and such characteristic is first stored in aspect ratio pair The storing sub-units of unit, wait detection means free time or detection to choose whether to carry out repeated measure by testing staff after completing And whether carry out further accurate data processing.
Above-described embodiment is the present invention preferably embodiment, but embodiments of the present invention not by above-described embodiment Limit, other any spirit without departing from the present invention and the change, modification, replacement made under principle, combine, simplification, Equivalent substitute mode is should be, protection scope of the present invention is included in.

Claims (8)

1. a kind of blood vessel state measurement apparatus based on program control companding, is characterized in that including that two have ultrasonic transmission/reception ability Flexible detection terminal, pneumatic companding bag, control module, detection module and speed governing air pump;Wherein pneumatic companding bag and control module It is connected, control module is connected with speed governing air pump, and detection module is connected with control module;Flexible detection terminal is responsible for ultrasound The driving and transmitting of detection signal, the reception of ultrasound echo signal and pretreatment, data communication;Pneumatic companding bag is worn on body On, pressure is applied to human body specific part according to the formula for having set;Control module is responsible for the parameter setting of whole device, companding The gating of each electromagnetic valve, the Power Control of speed governing air pump and man-machine interaction in formula selection, solenoid valve block;Detection module is responsible for inspection The generation of survey signal, the storage of detection data, the inverting of point fluctuation signal, the identification of blood vessel transport properties, local vascular conduction The identification and feature extraction of characteristic, local vascular aspect ratio to and data communication;Speed governing air pump is responsible for pumping into for air, speed governing gas The motor speed of pump is controlled by the speed-regulating signal that control module is exported.
2. a kind of blood vessel state measurement apparatus based on program control companding according to claim 1, it is characterised in that the gas Dynamic pressure is expanded bag and is made up of integral type air bag cloth bag, inflated hose;Wherein described integral type air bag cloth bag is weaved cotton cloth or second using soft Olefinic base material, is made up of multiple ballonets, is separated between multiple ballonets by way of sewing or hot sealing;Often Individual ballonet connects an inflated hose, and inflated hose is connected to the expansion bag gating solenoid valve block of control module, from speed governing air pump The gas circuit of connection is constituted to ballonet, and after formula gating, the stingy intracapsular air pressure of corresponding gas circuit connection increases with inflation, from And body local position is pressed.
3. a kind of blood vessel state measurement apparatus based on program control companding according to claim 2, it is characterised in that the control Molding block includes companding bag gating solenoid valve block, master controller and man-machine interaction unit;Companding bag gates solenoid valve block by multiple Solenoid valve block is constituted, and each solenoid valve block contains two electromagnetic valves, and one of electromagnetic valve is connected with speed governing air pump by trachea, Another is connected with the external world, by the electromagnetic force of solenoid in current control electromagnetic valve so that the valve of one of electromagnetic valve Door is opened, the valve closing of another electromagnetic valve;The electric current of each electromagnetic valve determined by master controller, if with speed governing air pump phase Electromagnetic valve even is opened, then turn on from the gas circuit of speed governing air pump to ballonet, and speed governing air pump pumps into air, ballonet drum to gas circuit Pressure is applied to human body ad-hoc location after rising;If the electromagnetic valve being connected with the external world is opened, from ballonet to extraneous gas circuit Conducting, the air in ballonet are discharged by electromagnetic valve;Master controller determines companding bag gating electricity according to the formula of setting The state of each electromagnetic valve and its persistent period in magnet valve group, the speed-regulating signal for being sent to speed governing air pump are determined according to formula, and then is controlled The stingy intracapsular air pressure of system connection;Man-machine interaction unit is responsible for man-machine interaction, for parameter setting, formula setting, control The output of the input and error message of order.
4. a kind of blood vessel state measurement apparatus based on program control companding according to claim 3, it is characterised in that the inspection Survey module include signal generating unit, fluctuation inverting unit, channel identifying unit, subchannel identification unit, feature extraction unit, Feature comparing unit, communication unit and data buffer storage unit;The signal generating unit be responsible for the generation of wideband detection signal with Drive, the wideband detection signal delivers to flexible detection terminal by communication unit;The fluctuation inverting unit is responsible for anti-to producing The test point position penetrated, structure are judged, and can be realized to cardiac muscle or pulse using the continuous detecting to test point position Point fluctuation carries out the multidimensional detection in time and space;The channel identifying unit is fluctuated to cardiac muscle and arteries and veins using cardiac muscle and pulse point The channel transfer functions that cardiovascular is constituted between test point of fighting are recognized;The subchannel identification unit is using between channel Cascade connection, is obtained the transmission characteristic of subchannel by decomposing to the channel transfer functions before and after pressure;The feature Extraction unit is analyzed using the time domain of signal processing method sub-channel transmission characteristic, frequency domain character;The aspect ratio pair The data of time-frequency characteristics and property data base that unit is responsible for sub-channel are compared, and then the state to local vascular is carried out Judge, correct judged result and feature are stored in property data base;The communication unit is responsible for flexible detection terminal and inspection The transmission of data and control information between module is surveyed, using wire/wireless communication pattern;The data buffer storage unit is responsible for caching Detection signal parameter, ultrasound echo signal data, control parameter.
5. a kind of blood vessel state measurement apparatus based on program control companding according to claim 3, it is characterised in that the tune Fast air pump has motor and inflatable mouth, and inflatable mouth is blown into extraneous air in trachea, and what is connected with speed governing air pump is stingy intracapsular The positive pressure increase of air, applies pressure to present position;The speed governing that motor speed is sent by master controller in control module Signal is controlled, and the stingy intracapsular pressure connected by controlled motor rotating speed control conducting gas circuit is strong, and then controls pressure dynamics.
6. a kind of blood vessel state measurement apparatus based on program control companding according to claim 4, it is characterised in that the inspection Before and after module is surveyed by pressing to local, the active measurement of channel transfer functions, is obtained using channel cascaded characteristic and signal processing The transmission characteristic of local vascular, carries out aspect ratio pair by feature extraction binding characteristic data base, to local vascular state and Its disease is carried out diagnosing, is predicted and curative effect tracking;Control module goes to control each ballonet in pneumatic companding bag by formula Pressure size and persistent period, so as to control the variation characteristic of channel transfer functions residing for local vascular, and then realize local blood The automatic measurement of pipe transmission characteristic.
7. a kind of blood vessel state measurement apparatus based on program control companding according to claim 1, it is characterised in that flexible inspection Survey terminal and receive the wideband detection signal that detection module is produced, through amplifying and being converted into surpassing by transmitting probe after D/A conversions Sound wave is simultaneously launched, and the ultrasound wave of transmitting is produced after running into ventricle wall or blood vessel wall and reflects to form ultrasonic echo, part ultrasound Echo is received by neighbouring ultrasound probe, and the echo-signal of reception is preserved through amplifying, after A/D conversions, and by logical Letter module is sent to detection module.
8. a kind of blood vessel state measurement apparatus based on program control companding according to claim 4, it is characterised in that:
The fluctuation inverting unit, the test point position for taking echo analysis and geometry principle to select ventricle wall and blood vessel wall And its change carries out the time domain/inversion in frequency domain in time and space, a time domain/frequency domain characteristic for fluctuation is obtained;
Input signal of the channel identifying unit by the use of cardiac muscle point fluctuation as channel, wrist or cervical region pulse above the fold Point fluctuation ripple as channel output signal, using digital signal processing method to the blood between input signal and output signal Pipe transfers function by identification;
The feature comparing unit, sub-channel transmission characteristic when/data of frequency feature and property data base compare, right The state of blood vessel to be detected judged, and shown in man-machine interaction unit, test position, blood vessel transmission function when/ Frequency feature, cardiac muscle point fluctuation, the fluctuation of pulse point and patient condition, age etc. are stored in storing sub-units, wherein comparison result energy Carry out classification process.
CN201710015056.8A 2016-11-23 2017-01-10 Vascular state measuring device based on program-controlled companding Expired - Fee Related CN106510656B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130046191A1 (en) * 2011-08-19 2013-02-21 Kang Ping Lin System and method to measure arterial pulse pressure signals
CN105407796A (en) * 2013-05-10 2016-03-16 富士通株式会社 Diagnostic device, diagnostic method and program
CN103349546A (en) * 2013-07-16 2013-10-16 吕品 Device and method for measuring pulse waves and blood pressures
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