CN106491245B - Valve clamping device - Google Patents
Valve clamping device Download PDFInfo
- Publication number
- CN106491245B CN106491245B CN201510561057.3A CN201510561057A CN106491245B CN 106491245 B CN106491245 B CN 106491245B CN 201510561057 A CN201510561057 A CN 201510561057A CN 106491245 B CN106491245 B CN 106491245B
- Authority
- CN
- China
- Prior art keywords
- clamping
- main part
- valve
- support portion
- clamping device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical group O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 8
- 239000008119 colloidal silica Substances 0.000 claims description 7
- 238000010586 diagram Methods 0.000 description 23
- 230000007246 mechanism Effects 0.000 description 19
- 210000004115 mitral valve Anatomy 0.000 description 11
- 229910000831 Steel Inorganic materials 0.000 description 8
- 239000010959 steel Substances 0.000 description 8
- 206010027727 Mitral valve incompetence Diseases 0.000 description 5
- 230000009471 action Effects 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- 230000002787 reinforcement Effects 0.000 description 5
- 230000008439 repair process Effects 0.000 description 5
- 229910001220 stainless steel Inorganic materials 0.000 description 5
- 229910001000 nickel titanium Inorganic materials 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 210000002837 heart atrium Anatomy 0.000 description 3
- 210000005240 left ventricle Anatomy 0.000 description 3
- 230000006386 memory function Effects 0.000 description 3
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 3
- 238000003466 welding Methods 0.000 description 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 229910045601 alloy Inorganic materials 0.000 description 2
- 239000000956 alloy Substances 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 125000004122 cyclic group Chemical group 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000005489 elastic deformation Effects 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 241000463219 Epitheca Species 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 206010067171 Regurgitation Diseases 0.000 description 1
- NRTOMJZYCJJWKI-UHFFFAOYSA-N Titanium nitride Chemical compound [Ti]#N NRTOMJZYCJJWKI-UHFFFAOYSA-N 0.000 description 1
- HZEWFHLRYVTOIW-UHFFFAOYSA-N [Ti].[Ni] Chemical compound [Ti].[Ni] HZEWFHLRYVTOIW-UHFFFAOYSA-N 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
- 210000000709 aorta Anatomy 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 210000003157 atrial septum Anatomy 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 238000009954 braiding Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 210000003191 femoral vein Anatomy 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000010247 heart contraction Effects 0.000 description 1
- 210000003709 heart valve Anatomy 0.000 description 1
- 239000012943 hotmelt Substances 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 210000005246 left atrium Anatomy 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 239000007779 soft material Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 210000000591 tricuspid valve Anatomy 0.000 description 1
- 238000004804 winding Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/246—Devices for obstructing a leak through a native valve in a closed condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00238—Type of minimally invasive operation
- A61B2017/00243—Type of minimally invasive operation cardiac
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2466—Delivery devices therefor
Abstract
The invention discloses a kind of valve clamping devices comprising support portion, main part and clamping part.There is the support portion first end, described main part one end to be connected with the first end, and the other end surrounds the support portion.The clamping part is enclosed set on the outside of the main part, and can the relatively described main part be radially unfolded or be closed centered on the first end.Implement the valve clamping device of the present invention, it is simple in structure, it is easy to use.
Description
Technical field
The present invention relates to the tissue repair instruments in a kind of human body, are clamped and fill more specifically to a kind of heart valve
It sets.
Background technology
Mitral regurgitation is characterized in that blood enters the left heart from the left ventricle of heart by insufficient mitral regurgitation
Room.During the normal circulation of heart contraction (systole phase), bicuspid valve is used as check-valves, to prevent oxygenated blood fluid from flowing back to a left side
Atrium.In this way, oxygenated blood fluid enters aorta by aortic valvo-pump.Valve regurgitation can significantly reduce the pumping effect of heart
Rate makes patient be among serious, progressive heart failure risk.
The most common treatment of mitral regurgitation depends on valve replacement or reparation, includes the remodeling of leaflet and annulus, after
Person is commonly known as annuloplasty.Mitral valve repair depends on the newest skill that the adjacent segment of opposite leaflet is stitched together
Art is referred to as " knot " or " edge-to-edge " technology.These technologies often rely on open openheart surgery, the wherein chest of patient
It is usually opened by sternotomy, and patient is placed in cardiovascular shunt.Recently, developed based on minimally invasive operative catheter
To the valve that implant clip is delivered to insufficiency.These folders are for the part of leaflet to be fixed together, by two bicuspid valve
Between gap be separated into two adjacent smaller gaps, to reduce reflux.
As shown in Figure 1 and Figure 2, it is (or solid to generally include proximal member 16 (or grip element) and distal member 18 for fixing device
Determine element), the free end of proximal member 16 is tilted towards the engagement surface near 18 free end of distal member, can be towards axis 12
Inwardly move through proximal member line 90 help recline axis 12 holding.Proximal member 16 is by manipulating 90 liters of proximal member line
High and reduction.Fig. 1 is that fixing device is transported to the open position in heart, that is, approaches after the mitral valve and first beat distal member 18
Open, keep proximal member to be arranged by paraxial 12 with proximal member line 90, as shown in Fig. 2, when mitral position in proximal element and
When between distal end member, release proximal member line 90 makes proximal member 16 be moved towards distal member 18, to capture leaflet
Or it keeps in-between.Bicuspid valve is held on proximal member 16 and distal member it is recognised that being realized in the prior art
It when between 18, needs to control proximal member 16 and distal member 18 successively, and the movement of proximal member 16 is needed by close
The cooperation of side element line 90 causes apparatus structure complicated, and reliability is insufficient, inconvenient for operation.
Invention content
The technical problem to be solved in the present invention is, complicated for the mitral valve repair device of the prior art, operation
Inconvenient defect, provides a kind of valve clamping device of avoidable drawbacks described above.
The technical solution adopted by the present invention to solve the technical problems is：
A kind of valve clamping device comprising：Support portion, the support portion have first end；Main part, the main part
One end is connected with the first end, and the other end surrounds the support portion；And clamping part, the clamping part are enclosed set on the main part
Outside, and can the relatively described main part be radially unfolded or be closed centered on the first end.
In an embodiment of the invention, the main part is reticular structure.
In an embodiment of the invention, the reticular structure, which is equipped with, reinforces webmaster.
In an embodiment of the invention, the main part is colloidal silica or cavernous body.
In an embodiment of the invention, the clamping part is equipped at least one anchoring close to the side of the main part
Part, the main part is equipped with location hole or locating slot, and under the clamping part closed state, the anchor log is embedded at matches therewith
To the location hole or locating slot in.
In an embodiment of the invention, the clamping part is equipped with multiple anchor logs, and at least one anchor log is sawtooth
Shape structure.
In an embodiment of the invention, the clamping part includes two folders for being located at the main part opposite sides
Gripping member, and two clamping pieces are mutually rotatablely connected in the end close to the first end.
In an embodiment of the invention, the valve clamping device further includes a driving portion, and the driving portion includes
One closed cell and an opening unit；The closed cell is at least partially disposed at the inside of the clamping part, and with it is described
Clamping part is connected, and for making the clamping part, the relatively described main part remains closed in a free state；The opening unit position
It is connected in the inside of the clamping part, and with the clamping part, for driving the relatively described main part of the clamping part to open.
In an embodiment of the invention, the closed cell be a torsional spring, the torsional spring include a spring body and
Two spring arms, two spring arms extend from two opposing end portions of the spring body respectively, and each spring arm with an institute
State clamping piece interconnection.
In an embodiment of the invention, the closed cell is a " V " shape shrapnel, every in the both ends of the shrapnel
One end is connected with each other with a clamping piece.
In an embodiment of the invention, the opening unit includes two gonnecting rod bodies, and each gonnecting rod body includes
The first connecting pin being oppositely arranged and second connection end, the first connecting pin of one of them gonnecting rod body and a folder
Gripping member is rotatablely connected, and the first connecting pin of another gonnecting rod body is rotatablely connected with another described clamping piece；Described in two
Second connection end is mutually rotatablely connected, and the support portion is in strip, two second connection ends of two gonnecting rod bodies
It can move axially set on the support portion and along the support portion.
Valve, can be by way of being held between main part and clamping part by the valve clamping device for implementing the present invention
Valve is repaired.Since one end of the main part is connected with the first end of the support portion, the main part it is another
End surrounds the support portion, therefore simple in structure.In addition, it is only necessary to carry out operation to clamping part to can be carried out valve and repair
It is multiple, thus it is easy to operate.
Description of the drawings
Present invention will be further explained below with reference to the attached drawings and examples, in attached drawing：
Fig. 1, Fig. 2 are the overall structure diagram of the fixing device of the prior art；
Fig. 3 is the overall structure diagram of the valve clamping device of the present invention, and valve clamping device includes support portion, main body
Portion, driving portion and clamping part, clamping part include two clamping pieces, and driving portion includes that an opening unit and one are closed list
Member；
Fig. 4 is the internal structure schematic diagram of the main part of the valve clamping device in Fig. 1；
Fig. 5 is the structural schematic diagram of the support portion of the valve clamping device in Fig. 1；
The structural schematic diagram being sheathed on based on Fig. 6 on support portion, main part include a net tubular body；
Fig. 7 is the structural schematic diagram of the net tubular body of the main part in Fig. 6；
Fig. 8 is the structural schematic diagram with the net tubular body for reinforcing webmaster, and it includes first group of wavy annular to reinforce webmaster
Object and second group of wavy annular object；
Fig. 9 is the structural representation of the first group of wavy annular object and second group of wavy annular object of the reinforcement webmaster in Fig. 8
Figure；
Figure 10 is the structural schematic diagram of clamping piece；
Figure 11 is the structural schematic diagram of closed cell；
Figure 12 is the structural schematic diagram of the gonnecting rod body of opening unit；
Figure 13 is the structural schematic diagram of valve clamping device coupling part transport system；
Figure 14, Figure 16, Figure 17 are to convey valve clamping device using transport system mitral each step is clamped
Schematic diagram；
Figure 15 is in the structural schematic diagram of closed state for the valve clamping device in Figure 14；
Figure 18, Figure 19 are the structural schematic diagram of the valve clamping device of second embodiment of the invention；
Figure 20 is the structural schematic diagram of closed cell in second embodiment；
Figure 21 is the structural schematic diagram of the valve clamping device of third embodiment of the invention；
Figure 22 is the structural schematic diagram of closed cell in 3rd embodiment；
Figure 23 is the overall structure diagram of the valve clamping device of fourth embodiment of the invention；
Figure 24 is the schematic diagram of the closed cell of fourth embodiment of the invention；
Figure 25 is the overall structure diagram of the valve clamping device of fifth embodiment of the invention；
Figure 26 is the overall structure diagram of the valve clamping device of sixth embodiment of the invention；
Figure 27 is the structural schematic diagram that the valve clamping device of Figure 25 is connect with transport system；
Figure 28 is that the valve clamping device of the 5th embodiment is delivered to the schematic diagram in human body with transport system.
Specific implementation mode
For a clearer understanding of the technical characteristics, objects and effects of the present invention, now control attached drawing is described in detail
The specific implementation mode of the present invention.
It should be noted that when element is referred to as " being fixed on " or " being set to " another element, which can be straight
Grounding connection can also be connected to another element indirectly on another element by one or more connecting element
On.When an element is known as " being connected to " another element, it can be connected directly on another element, or
It is connected on another element by one or more connecting element.
Valve clamping device provided by the present invention can be used for repairing bicuspid valve, it can also be used to repair tricuspid valve.Hereafter with
The valve clamping device of the present invention is illustrated for reparation bicuspid valve.It is used only as illustrating it is to be understood that being described below, not
It is limitation of the present invention.
Fig. 3, Fig. 4 provide the valve clamping device 100 of first embodiment of the invention.Valve clamping device 100 includes branch
Support part 10, main part 20, clamping part 30 and driving portion 40.
The support portion 10 is in a tubular form and with opposite first end 11 and second end 12.The circumferential ring of the main part 20
Set on 10 outside of the support portion.One end of the main part 20 is fixedly connected with 10 first end 11 of the support portion, the master
Body portion 20 surrounds support portion 10.The clamping part 30 is enclosed set on the outside of the main part 20, one end and support portion 10
First end 11 is rotatablely connected, and the other end main part 20 radially can be unfolded or be closed centered on the first end 11 relatively
It closes.The clamping part 30 is towards being additionally provided with anchor log 33 on the side of main part 20；Main part 20 is equipped with location hole or fixed
Position slot 23.When clamping part 30 is closed, anchor log 33 passes through valve in corresponding location hole or locating slot 23, makes
Valve is held between clamping part 30 and main part 20.The driving portion 40 includes that a closed cell 41 and one open list
Member 42；41 part of the closed cell is located at 30 inside of the clamping part and is connected with the clamping part 30, for making the folder
Holding portion 30, the main part 20 remains closed relatively in a free state；The opening unit 42 is located inside the clamping part,
And be connected with the clamping part 30, for the clamping part 30 to be opened from the closed state main part 20 relatively.
Referring to Fig. 5, support portion 10 further includes 13, bar shaped guiding pieces 14 of a connector and one first connection
Hole 15；The connector 13 is set to second end 12, detachably connects for the interior sheath 50 (referring to Figure 13) with transport system 500
It connects；The bar shaped guiding piece extends radially through the support portion and along the axially extending strip through-hole of the support portion, is used for for 14
The opening unit 42 is guided to be moved relative to the support portion 10；First connecting hole 15 is close to the first end 11, diameter
To the first end 11 through the support portion 10, for accommodating the first pivot 32.
It should be noted that connector 13 is preferably the external screw thread for being set to 12 circumferential surface of second end, certain connector 13
It can be the other structures such as buckle or hook, be connected as long as may be implemented to match with transport system 500.Bar shaped guiding piece 14
Can be set on 10 outer surface of the support portion, and along the axially extending groove of the support portion 10.
It should also be noted that, support portion 10 preferably uses outer diameter 1.4mm-1.6mm, the 316L of internal diameter 1.0mm-1.2mm
Stainless steel tube or nickel-titanium metal pipe are made.
Also referring to Fig. 6, Fig. 7, main part 20 is elastic component and is in reticular structure comprising a net tubular body
21 and two fixing pieces 24；Net tubular body 21 is sheathed on support portion 10, is connected by a fixing piece 24 per one end
Set on 10 surface of support portion.
Fixing piece 24 is preferred to select steel screw bushing.When forming main part 20, first by the net tubular body of both ends open
21 are sheathed on 10 outside of support portion, fixing piece 24 are sheathed on 10 surface of support portion later, and make each of net tubular body 21
End is held on respectively between 24 inner surface of fixing piece and 10 outer surface of support portion, further passes through laser welding fixing piece 24
Realize the both ends of net tubular body 21 and being fixedly connected for support portion 10.Net tubular body 21 is sheathed on the length on support portion 10
It is limited with the height in 30 closed state of clamping part not less than 30 free end end face of clamping part.
It is understood that the mode that net tubular body 21 is connect with support portion 10 is not limited by steel screw bushing connection,
Directly the both ends of net tubular body 21 can also be connected with the both ends of support portion 10 respectively by welding manner.Preferably, it is
Easily manufactured, connector 13 can be the helicitic texture for being set to 24 outer surface of fixing piece.
As shown in fig. 7,21 both ends open of net tubular body.The net tubular body 21 includes a plurality of interlaced and in
The braided wires 22 of mandrel helically coiling.It intersects to form multiple grids between multiple braided wires 22, at this point, multiple grid-shaped
At the location hole or locating slot 23 with the pairing setting of the anchor log 33 of clamping part 30.Net tubular body 21 is preferably by with superlastic
Property shape memory function material braiding made of reticular structure, such as Nitinol.
Net tubular body 21 is connected with after on support portion 10, and the meshy surface of net tubular body 21 is formed to be connect with natural valve
The middle section in tactile face, net tubular body 21 is naturally swelling with respect to 10 surface of support portion, and a fortune is formed with 10 surface of support portion
Dynamic space, make net tubular body 21 can radial force retraction, while also providing an opposition.
Also referring to Fig. 8, Fig. 9, in order to further increase the radial support power of net tubular body 21, it is preferable that webmaster
Shape ontology 21, which is equipped with, reinforces webmaster 25.Reinforcement webmaster 25 is wavy annular object.The wavy annular object includes first group of corrugated gasket
Shape object 251 and second group of wavy annular object 252.Interlaced coiling between adjacent sets wavy annular object, cooperatively forms mesh,
Every group of wavy annular object is by wire rings around formation.Reinforce webmaster 25 wire along net tubular body 21 circumference according to
The secondary mesh across net tubular body 21 makes reinforcement webmaster 25 and net tubular body 21 be woven together.It can certainly use
Suture is directly sutured in webmaster 25 is reinforced on net tubular body 21.It should be noted that the reinforcement webmaster 25 with part or
Whole net tubular bodies 21 are arranged or intersect to wear and knit.
In order to further improve the radial support power of net tubular body 21, net tubular body 21 or the double-deck knot
Structure, the reinforcement webmaster 25 are at least partly arranged with internal layer and/or outer layer net tubular body 21 or intersect to wear and knit.
It will also be appreciated that main part 20 can also be made of other soft materials, such as main part 20 can be to adopt
The colloidal silica made of silica gel is either using cavernous body (not shown) made of sponge.The both ends of colloidal silica or cavernous body are logical
The mode for crossing bonding or hot melt etc. is connected with the surface of support portion 10.The colloidal silica and cavernous body can be solid or empty
Core structure.Solid colloidal silica or cavernous body is equipped with the locating slot for being matched with anchor log 33；Hollow colloidal silica or sea
Continuous body is equipped with the location hole for being matched with anchor log 33.
It is also understood that main part 20 or non-elastic member, the material of the non-elastic member is, for example, stainless steel
Or iron etc..The stiff main part 20 can be reality/hollow-core construction or be in netted setting.When stiff main part 20
When in netted setting, can be by be cut by laser formed, both ends preferably using weld by the way of with 10 surface phase of support portion
Even；When stiff main part 20 be in solid or hollow-core construction when, support portion 10 pass through main part 20, the two of main part 20
End is still preferably connected by the way of welding with 10 surface of support portion.
Simultaneously, it should be noted that in the present embodiment, the position that net tubular body 21 is sheathed on support portion 10 makes bar shaped
Guiding piece 14 is located in the inside of net tubular body 21, and support portion 10 be connected with clamping piece 31 by opening unit 42, therefore,
Main part 20 is equipped with the opening 26 for making opening unit 42 stretch out and moving.It is understood that working as net tubular body
When 21 positions being sheathed on support portion 10 make bar shaped guiding piece 14 be located at net 21 outside of tubular body, since main part 20 will not
The movement of opening unit 42 is hindered, therefore in such cases, opening 26 can be omitted should not.
Referring again to Fig. 2, valve is held between main part 20 and clamping part 30 by clamping part 30 with that can match
It is limited.Clamping part 30 includes two clamping pieces 31 for can be opposite opening and closing and being rotatably connected with support portion 10.Two clamping pieces
31 are connected to 15 position of the first connecting hole of support portion 10 by the first pivot 32.It can be understood that the first pivot 32 here
It may include an axis body, can also include the multiple axis bodies for being set to same axis.
Please also refer to Figure 10, each clamping piece 31 takes the shape of the letter U structure comprising two side plates 311 being oppositely arranged, with
An and intermediate plate 312 being located between two side plates 311.Two side plates 311 are connected to opposite two of intermediate plate 312
Lateral margin, and two side plates 311 are bent to form U-shaped structure in the same direction with respect to intermediate plate 312.Each side plate 311 is far from intermediate plate 312
One side edge is equipped at least one anchor log 314.In the present embodiment, the number of at least one anchor log 314 is multiple, and should
Multiple anchor logs 314 form laciniation.It is understood that the opening of the U-shaped structure is towards main part 20.It can also manage
Solution, multiple anchor log 314 can also form rectangular wave structure or sinusoidal configuration.It will also be appreciated that described
The number of at least one anchor log 314 may be one, at this point, the section of the anchor log 314 can trapezoidal, triangle,
The shapes such as semicircle.
The length of intermediate plate 312 is less than the length of side plate 311, so that intermediate plate 312 is homogeneously stretched in each 311 one end of side plate
Go out, forms a linkage section 313.Hollow region is formed between two linkage sections 313.Connect as described above, the first pivot 32 passes through
It connects section 313 and the support portion 10 and the clamping piece 31 is rotatablely connected by the first connecting hole 15.
Each clamping piece 31 further includes two the second connecting holes 315 being arranged in respectively on two side plates 311.This two
Two connecting holes 315 are oppositely arranged.
Each clamping piece 31 further includes the connecting rod 316 for being connected with closed cell 41, and the connecting rod 316 is set to
Between two side plates 311, and the opposite end of connecting rod 316 is connected with two side plates 311 respectively.It is preferred that connecting rod 316 is successively
The connection with two side plates 311 is realized across two side plates 311.Need to illustrate at this time when, when can realize in other ways
Between two side plates 311 when the fixation of spacing, intermediate plate 312 can also omit.For example, when being equipped with connecting rod 316 and connecting rod
When 316 opposite end is fixed to each other with two side plates 311 respectively, intermediate plate 312 can omit.
The side plate 311 and intermediate plate 312 of clamping piece 31 preferably select the stainless steels of 316L using 0.3mm-0.5mm
At.
As shown in figure 11, the closed cell 41 of first embodiment is preferably the torsional spring made of 316L stainless steel wire coilings.
The closed cell 41 includes spring body 411 and two the first spring arms 412；Spring body 411 is hollow around being formed by steel wire spiral
Cyclic structure；Two the first spring arms 412 extend from 411 liang of opposing end portions of spring body respectively, and each first spring arm 412 includes
One by 411 end of spring body it is tangentially extending go out straight arm section 413 and one by first straight arm section 413 far from spring body 411
The first circle body 414 that one end helically coiling is formed.When installation, each first circle body 414 is sheathed on the company of a clamping piece 31
On extension bar 316, each straight arm section 413 forms hollow region between both passing through two linkage sections 313 of a clamping piece 31, and closes
The spring body 411 for closing unit 41 is located at the outside (as shown in Figure 4) of clamping part 30, to realize closed cell 41 and clamping part 30
Connection.
Angle between two the first spring arms 412 in free state can be such that two clamping pieces 31 are pressed from both sides with respect to main part 20
Tightly it is limited.It is 0 ° -30 ° that angle between first spring arm 412 descends in the raw in torsional spring, preferably chooses 10 °.Due to first
Angle between spring arm 412 is smaller, then two clamping pieces 31 can be closed in a free state with respect to main part 20.
It should be understood that spring body 411 due to not constraining, can be located in two 31 insides of clamping piece, it can also be from folder
Space between two linkage sections 313 of gripping member 31 reaches the outside of clamping piece 31.In the present embodiment, spring body 411 is by steel wire
Continuous helical coiling is formed, it is reserved make 10 first end 11 of support portion by space, to which spring body 411 reaches clamping piece 31
Outside.
Please also refer to Fig. 1, Fig. 2 and Figure 12, the opening unit 42 includes two gonnecting rod bodies 420.Each company
The body of rod 420 includes the first connecting pin 426 for being oppositely arranged and second connection end 427, wherein the of gonnecting rod body 420
One connecting pin 426 and a clamping piece 31 are rotatablely connected, the first connecting pin 426 and another clamping of another gonnecting rod body 420
Part 420 is rotatablely connected；Two second connection ends 427 are mutually rotatedly connected, and can be moved axially with respect to support portion 10.
In the present embodiment, the first connecting pin 426 of each gonnecting rod body 420 pass through the second pivot 423 and clamping piece 31 the
It is rotatedly connected at two connecting holes 315, that is to say, that the second pivot 423 passes through the first connecting pin 426 and the second connecting hole 315 will
The opening unit 42 is connected with clamping part 30；The second connection end 427 of each connecting rod 420 passes through third pivot 425 and support
It is connected at the bar shaped guiding piece 14 in portion 10, that is to say, that third pivot 425 passes through two second connection ends 427 and bar shaped to guide
The opening unit 42 is connected by part 14 with support portion 10, to realize that the opening unit 42 is connected with clamping part 30, and institute
Stating opening unit 42 can be with respect to the axial movement of support portion 10.
Specifically, each gonnecting rod body 420 includes two first bodies of rod 421 and second body of rod 422.It is described two
First body of rod 421 is arranged in parallel；Second body of rod 422 is set between two first bodies of rod 421, for being kept for two
Spacing between the body of rod.
In installation condition, two first bodies of rod 421 are sheathed on the second pivot 423 and are set to the first side plate 311 and second
Part between side plate 311；Third pivot 425 passes through first body of rod 421 and bar shaped guiding piece 14 and support portion 10 is made to be set to
Between two bodies of rod, the diameter of third pivot 425 is less than the width of bar shaped track, and third pivot 425 is enable to draw along bar shaped
Guiding element 14 moves axially.
It can be understood that：Second body of rod 422 can not also be set, as long as between can keeping two first bodies of rod 421
Relative distance.It should be noted that when bar shaped guiding piece 14 is radial break-through leading in the opposite flank of support portion 10
Kong Shi, third pivot 425 are an axis body, pass through bar shaped guiding piece 14 and both ends are stretched out from 10 surface of support portion.It is appreciated that
, when bar shaped guiding piece 14 number be two, and two bar shaped guiding pieces 14 be respectively arranged on outside the support portion 10
Surface opposite sides and when along two axially extending grooves of the support portion 10, is substituted using two coaxial pivots
Three pivots 425 can also realize the purpose of the present invention, and at this time, one end of every pivot is contained in a groove, and can edge
The axial movement of the support portion 10.
Gonnecting rod body 420 is preferably selected to be made using the 316L stainless steels of 0.3mm-0.5mm.
It is shown in Figure 13, in order to realize the push-and-pull to third pivot 425.It is additionally provided with push-pull rod on third pivot 425
424, which is contained in inside tubular support portion 10, for being connected with the push-pull mechanism 52 of transport system 500.Push-and-pull
424 one end of bar makes third pivot 425 radially across realization is fixedly connected with third pivot 425；Push-pull rod 424 it is another
Hold, mode for be connected through a screw thread and transport system 500 axially extending towards the direction where 10 second end of support portion 12
It is connected.The outer diameter of push-pull rod 424 is less than the internal diameter in tubular support portion 10, and push-pull rod 424 can be axially moved with respect to support portion 10.
It should be noted that in order to make instrument that there is good biocompatibility, in institute by way of ion vapor deposited
There is the surface of metal parts to plate one layer of biocompatible materials, e.g. titanium nitride coating, this technology has been known technology, herein
Just it repeats no more.
Shown in Figure 13 to Figure 17, when being repaired to bicuspid valve, first via femoral vein enter to endocardial,
Further enter atrium sinistrum by puncturing atrial septum, enters left ventricle simultaneously then across the gap between mitral two leaflets
And making valve clamping device 100 close to the position where bicuspid valve, valve clamping device 100 is placed in transport system 500 at this time
Outer sheath 50 inside, the connection for the interior sheath 51 and valve clamping device 100 of transport system 500 being contained in outer sheath 50
First 13 be connected, the push-pull mechanism 52 of transport system 500 is contained in interior sheath 51, and with the push-pull rod of valve clamping device 100
424 are connected；Withdrawing outer sheath 50 makes valve clamping device 100 be stretched out from outer sheath 50, further, in the guiding of three-D ultrasonic
Under, push third pivot 425 to make two clamping pieces 31 are opposite to open by the push-pull mechanism 52 of transport system 500；Later, to the left
Atrium withdraws the following table of a side surface and a leaflet that valve clamping device 100 makes where the anchor log 33 of a clamping piece 31
Face contacts, and makes mitral position between main part 20 and clamping part 30；Then, push-pull mechanism 52 is released to third pivot 425
Impetus, two clamping pieces 31 are relatively closed under the action of closed cell 41, and anchor log 33 passes through valvular tissue, and anchor
Determine being inserted partially into main part 20 across valvular tissue of part 33.Since main part 20 is elastic component, main part 20 is being clamped
Stress occurs also to provide a radial support power to clamping piece 31 while elastic deformation under the action of part 31, makes valve by tightly
It is held between clamping piece 31 and main part 20, the gap between mitral two leaflets is thus by a larger gap point
Two smaller gaps are divided into, to reduce the possibility of mitral regurgitation；Push-pull mechanism 52 and interior sheath are finally released respectively
The connection of pipe 51 and valve clamping device 100, and transport system 500 is withdrawn from vitro, so that valve clamping device 100 is individually clamped
In being repaired to valve on valve.
Embodiment two：
Figure 18 and Figure 19 show the valve clamping device 100a of second embodiment of the invention.Valve clamping device 100a with
Valve clamping device 100 in first embodiment is substantially the same comprising a support portion 10a, a main part 20a, one
An a clamping part 30a and driving portion 40a.Clamping part 30a includes two clampings for being relatively arranged on the both sides main part 20a
Part 31a, clamping piece 31a are equipped with connecting rod 316a.Driving portion 40a includes a closed cell 41a and opening unit 42a.
The difference is that the closed cell 41a in the present embodiment is (as shown in figure 20) using " V " shape shrapnel, the shrapnel
It is made of the alloy of super-elastic shape memory function, such as Nitinol.The shrapnel include two extend in the same direction out second
Spring arm 412a.Each second spring arm 412a includes the second straight arm section 413a, and from second one end straight arm section 413a spiral winding
Make the second circle body 414a formed.Two one end of the second straight arm section 413a far from the second circle body 414a are interconnected to form V-arrangement
Structure, preferably two the second straight arm section 413a are integrally formed.
Second circle body 414a is sheathed on connecting rod 316a, the connection position of the v-shaped structure of shrapnel close to two clamping piece 31a
It sets.Angle between two the second spring arm 412a in free state can be such that two clamping piece 31a are clamped with respect to main part 20a
It is limited, such as the angular range between the second spring arm 412a is 0 ° -30 °, preferably selects 10 °.
Embodiment three：
Referring to Figure 21, the valve clamping device 100b of third embodiment of the invention is filled with the valve clamping in first embodiment
It is substantially the same to set 100a comprising support portion a 10b, main part a 20b, a clamping part 30b and a driving
Portion 40b.Support portion 10b includes two opposite first end 11b and second end 12b.Clamping part 30b is oppositely arranged including two
Clamping piece 31b in the both sides main part 20b.Driving portion 40b includes a closed cell 41b and opening unit 42b.
Referring to Figure 22, closed cell 41b is torsional spring comprising spring body 411b, is prolonged respectively from two opposing end portions of spring body 411b
The the first spring arm 412b stretched out；Spring body 411b is in by steel wire spiral around the cyclic structure formed, each first spring arm 412b packets
Include by the ends spring body 411b it is tangentially extending go out the first straight arm section 413b and by the first straight arm section 413b far from spring body 411
The first circle body 414b that one end helically coiling is formed.
The difference is that the spring body 411b in first embodiment includes only one formed by steel wire continuous helical coiling
A annular element, and spring body 411b includes two spaced in the present embodiment, is formed respectively by steel wire continuous helical coiling
First annular part 4111 and the second annular element 4112, and pass through steel wire between first annular part 4111 and the second annular element 4112
It is connected.The size of space between two annular elements meets：Support portion 10b first ends 11b can be made from first annular part 4111 and
Pass through between second ring part 4112.
Since spring body 411b has the space that support portion 10b can be made to pass through, then spring body 411b is contained in two clamping piece 31b
Inside, the length of the first spring arm 412b is shorter at this time, reduces the specification of torsional spring.
Example IV
Referring to Figure 23, the valve clamping device 100c of fourth embodiment of the invention is filled with the valve clamping in second embodiment
It is substantially the same to set 100b comprising support portion a 10c, main part a 20c, a clamping part 30c and a driving
Portion 40c.Support portion 10c includes two opposite first end 11c and second end 12c, and clamping part 30c is oppositely arranged including two
Clamping piece 31c in the both sides main part 20c.Driving portion 40c includes a closed cell 41c and opening unit 42c.
Closed cell 41c uses " V " shape shrapnel, the shrapnel to be made of the alloy of super-elastic shape memory function, such as
Nitinol.The shrapnel includes two the second spring arm 412c extended in the same direction out.Each second spring arm 412c includes the second straight-arm
Section 413c, and the second circle body 414c from second one end straight arm section 413c helically coiling formation.Two the second straight arm section 413c
One end far from the second circle body 414c is interconnected to form v-shaped structure, and preferably two the second straight arm section 413c are integrally formed.
The difference is that being equipped in the middle part of shrapnel V-structure for making support portion 10c first ends 11c wear in the present embodiment
The through-hole 411c crossed.The size of through-hole 411c is can make support portion 10c first ends 11c from through-hole 411c by being limited.Due to V
The space that support portion 10c passes through can be made by having in shape structure, and entire shrapnel is contained on the inside of two clamping piece 31c, the first spring
The length of arm 412c is shorter, reduces the specification of shrapnel entirety.
Embodiment five
As shown in figure 25, the valve clamping device 100d of fifth embodiment of the invention is clamped with the valve in fourth embodiment
Device 100d is substantially the same comprising the support portion 10d, main part 20d, a clamping part 30d of a tubulose, and
One driving portion 40d.Support portion 10d includes two opposite first end 11d and second end 12d, and clamping part 30d includes two
It is relatively arranged on the clamping piece 31d of the both sides main part 20d.Driving portion 40 includes a closed cell 41d and opening unit 42d.
Opening unit 42d includes third pivot 425d, is connected with push-pull rod 424d on third pivot 425d, the push-pull rod
424d is located in inside support portion 10d, for being connected (referring to Figure 27) with the push-pull mechanism 52 of transport system 500.Closed cell
41d is V-type shrapnel, and the through-hole for making support portion 10d first ends 11d pass through is equipped in the middle part of V-structure (referring to Figure 27).
The difference is that first end 11d passes through the through-hole formation connector 13d (not shown) on V-arrangement shrapnel.The connection
Head 13d preferably using being set to the external screw threads of first end 11d circumferential surfaces, for realizing with transport system 500 interior sheath 51 (referring to
Being detachably connected Figure 27).Meanwhile difference further includes, the one end of push-pull rod 424d far from third pivot 425d is directed towards
What the direction where first end 11d extended, the mode being connected through a screw thread is with 500 push-pull mechanism 52 of transport system (referring to figure
27) it is connected.
Embodiment six
As shown in figure 26, the valve clamping device 100e that sixth embodiment of the invention provides and the valve in 3rd embodiment
Clamping device 100c is substantially the same comprising support portion a 10e, main part a 20e, clamping part a 30e, Yi Jiyi
A driving portion 40e.Support portion 10e includes two opposite first end 11e and second end 12e.Clamping part 30e includes two phases
To being set to the clamping piece 31e of the both sides main part 20e.Driving portion 40e includes a closed cell 41e and opening unit 42e.It beats
It includes third pivot 425e to open unit 42e, and push-pull rod 424e is connected on third pivot 425e, and push-pull rod 424e is located in branch
Inside the 10e of support part, for being connected (referring to Figure 27) with the push-pull mechanism 52 of transport system 500.Closed cell 41e is to be set to two
The spring body of torsional spring between a clamping piece 31e, the torsional spring includes that spaced first annular part and the second annular element (are not marked
Number).
The difference is that intervals of the first end 11e across first annular part and the second annular element (not labeled)
Form connector 13e.Connector 13e preferably using being set to the external screw threads of first end 11e circumferential surfaces, for realizing with delivery system
The interior sheath 51 of system 500 is detachably connected (referring to Figure 27).Meanwhile difference further includes, push-pull rod 424e is far from third pivot
One end of axis 425e is directed towards the direction extension where first end 11e, the mode being connected through a screw thread and transport system 500
Push-pull mechanism 52 (referring to Figure 27) is connected.
Please also refer to Figure 27 and Figure 28, in the five, the 6th two embodiments, being will by way of apex of the heart puncture
Valve clamping device is delivered in human body.By taking the valve clamping device 100d of the 5th embodiment as an example, specific operation process is such as
Under：Valve clamping device, which is delivered in left ventricle, by transport system 500 by way of apex of the heart puncture makes valve clamping dress
It is disposed adjacent to mitral valve position, the interior sheath 51 of transport system 500 is connected with connector 13d at this time, and transport system 500 pushes away
Drawing mechanism 52 is connected with push-pull rod 424d, and valve clamping device 100d is placed in inside outer sheath 50；Withdrawing outer sheath 50 makes valve
Film clamping device 100d is stretched out from outer sheath 50；Further, under the guiding of three-D ultrasonic, pass through pushing away for transport system 500
Drawing mechanism 52 pulls third pivot 425d to make two clamping piece 31d are opposite to open；Later valve clamping device is pushed to atrium sinistrum
A side surface where 100d makes two clamping piece 31d anchor logs 33d is contacted with the lower surface of two leaflets respectively, and makes two
Leaflet is between main part 20d and clamping part 30d；Push-pull mechanism 52 is released to the pulling function of third pivot 425d, two
Clamping piece 31d is relatively closed under the action of closed cell 41d, and anchor log 33d passes through valvular tissue, and anchor log 33d is passed through
In the locating slot for being inserted partially into main part 20d or location hole (not labeled) of valve.It is main since main part 20d is elastic component
Elastic deformation occurs for body portion 20d stress under the action of clamping piece 31d, provides a radial support power to clamping piece 31d, makes valve
Film is tightly held between clamping piece 31d and main part 20d, at this point, the gap between mitral two leaflets is by one
Larger spaces separate is at two smaller gaps, to reduce mitral regurgitation.
Referring again to Figure 13 to Figure 14 and Figure 27 to Figure 28, the present invention also provides one kind for conveying valve clamping
The transport system 500 of device a comprising outer sheath 50, an interior sheath 51 and a push-pull mechanism 52；The epitheca
Pipe 50 is sheathed on 51 outside of the interior sheath and can the relatively described axial movement of interior sheath 51；The interior sheath 51 is sheathed on push-and-pull
It the outside of mechanism 52 can the relatively described axial movement of push-pull mechanism 52.
It is illustrated by taking first embodiment as an example, outer sheath 50 is for making valve clamping device 100 be delivered to human body
It is placed in the process wherein, the interior sheath 51 is connected with the support portion 10 of the valve clamping device 100, for that will be placed in
Valve clamping device 10 in outer sheath 50 is discharged from outer sheath 50；The push-pull mechanism 52 is connected with clamping part 30, is used for
The relatively described main part 20 of the clamping part 30 is driven to open and close.
Interior sheath 51 is equipped with upper first connecting portion (not labeled), which is be set to 51 end of interior sheath interior
Screw thread, the first connecting portion are detachably connected with the external screw thread on the connector 13 of valve clamping device；Push-pull mechanism 52 includes
Second connecting portion (not labeled), second connecting portion are connected with push-pull rod 424.By 51 fixed support portion 10 of interior sheath, push or
Person pulls push-and-pull machine 52, opening unit 42 that clamping piece 31 is driven to be opened and closed with respect to main part 20 under the action of push-pull rod 424.
It should be noted that the push-pull mechanism 52 has certain rigidity, wirerope is preferably selected as push-pull mechanism 52.
In conclusion valve clamping device using the present invention, it can be by the way that valve be held between clamping part main part
Mode repair valve, it is simple in structure, at the same main part need not be operated can achieve the purpose that clamp valve, use
It is convenient.
The embodiment of the present invention is described with above attached drawing, but the invention is not limited in above-mentioned specific
Embodiment, the above mentioned embodiment is only schematical, rather than restrictive, those skilled in the art
Under the inspiration of the present invention, without breaking away from the scope protected by the purposes and claims of the present invention, it can also make very much
Form, all of these belong to the protection of the present invention.
Claims (11)
1. a kind of valve clamping device, including：
Support portion, the support portion have first end；
Main part, described main part one end are connected with the first end, and the other end surrounds the support portion, and
Clamping part, the clamping part are enclosed set on the outside of the main part；
Driving portion, the driving portion are connect with the clamping part, with drive the clamping part can the relatively described main part with described
Radially it is unfolded or is closed centered on first end.
2. valve clamping device according to claim 1, which is characterized in that the main part is reticular structure.
3. valve clamping device according to claim 2, which is characterized in that the reticular structure, which is equipped with, reinforces webmaster.
4. valve clamping device according to claim 1, which is characterized in that the main part is colloidal silica or sponge
Body.
5. valve clamping device according to claim 1, which is characterized in that the clamping part close to the main part one
Side is equipped at least one anchor log, and the main part is equipped with location hole or locating slot, described under the clamping part closed state
Anchor log is embedded in the paired location hole or locating slot.
6. valve clamping device according to claim 5, which is characterized in that the clamping part is equipped with multiple anchor logs, and
At least one anchor log is laciniation.
7. valve clamping device according to any one of claims 1 to 6, which is characterized in that the clamping part includes two
It is located at the clamping piece of the main part opposite sides, and two clamping pieces are mutual in the end close to the first end
Rotation connection.
8. valve clamping device according to claim 7, which is characterized in that the driving portion includes closed cell and opening
Unit；The closed cell is at least partially disposed at the inside of the clamping part, and is connected with the clamping part, for making the folder
Holding portion, the relatively described main part remains closed in a free state；The opening unit is located at the inside of the clamping part, and with
The clamping part is connected, for driving the relatively described main part of the clamping part to open.
9. valve clamping device according to claim 8, which is characterized in that the closed cell is torsional spring, the torsional spring
Including spring body and two spring arms, two spring arms extend from two opposing end portions of the spring body respectively, and each spring
Arm is connected with each other with a clamping piece.
10. valve clamping device according to claim 8, which is characterized in that the closed cell is " V " shape shrapnel, institute
Every one end in the both ends of shrapnel is stated to be connected with each other with a clamping piece.
11. valve clamping device according to claim 8, which is characterized in that the opening unit includes two gonnecting rod bodies,
Each gonnecting rod body includes the first connecting pin being oppositely arranged and second connection end, and the of one of them gonnecting rod body
One connecting pin is rotatablely connected with a clamping piece, the first connecting pin of another gonnecting rod body and another described clamping
Part is rotatablely connected；Two second connection ends are mutually rotatablely connected, and the support portion is in strip, two gonnecting rod bodies
Two second connection ends are set to the support portion and can be moved axially along the support portion.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510561057.3A CN106491245B (en) | 2015-09-06 | 2015-09-06 | Valve clamping device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510561057.3A CN106491245B (en) | 2015-09-06 | 2015-09-06 | Valve clamping device |
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| CN106491245A CN106491245A (en) | 2017-03-15 |
| CN106491245B true CN106491245B (en) | 2018-08-07 |
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| CN102860846A (en) * | 2012-09-05 | 2013-01-09 | 中国人民解放军第一0一医院 | Tricuspid valve edge-to-edge clip device capable of being implanted through catheter |
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| CN106491245A (en) | 2017-03-15 |
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Effective date of registration: 20240103 Address after: 518051 1604, Xianjian technology building, No. 22, Keji South 12th Road, gaoxinyuan community, Yuehai street, Nanshan District, Shenzhen, Guangdong Province Patentee after: Shenzhen Jianxin Medical Technology Co.,Ltd. Address before: 518000 1st-5th Floor of Saiba Research Building, Langshan Second Road, North District of Nanshan High-tech Industrial Park, Shenzhen City, Guangdong Province Patentee before: LIFETECH SCIENTIFIC (SHENZHEN) Co.,Ltd. |