CN106474319A - A kind of pharmacy disinfectant and preparation method thereof - Google Patents

A kind of pharmacy disinfectant and preparation method thereof Download PDF

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Publication number
CN106474319A
CN106474319A CN201610777036.XA CN201610777036A CN106474319A CN 106474319 A CN106474319 A CN 106474319A CN 201610777036 A CN201610777036 A CN 201610777036A CN 106474319 A CN106474319 A CN 106474319A
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parts
herba
disinfectant
pharmacy
bulbus allii
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CN201610777036.XA
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Chinese (zh)
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郭凤玲
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/40—Liliopsida [monocotyledons]
    • A01N65/42—Aloeaceae [Aloe family] or Liliaceae [Lily family], e.g. aloe, veratrum, onion, garlic or chives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234—Cnidium (snowparsley)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/483—Gleditsia (locust)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/85—Verbenaceae (Verbena family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Abstract

The invention discloses a kind of pharmacy disinfectant and preparation method thereof, it is prepared from by Herba pteridis vittatae, Spina Gleditsiae, Folium Artemisiae Argyi, Herba Artemisiae Annuae, Bulbus Allii, Herba Ephedrae, Fructus Viticises, Borneolum Syntheticum, Fructus Cnidii, Myrrha and Semen Cuscutae, weigh each crude drug by proportioning, clean and dry, be placed in after chopping in container, add water to cook three times, united extraction liquid, filter, Bulbus Allii juice is added in extracting solution, stirs, filter again, filtrate fill is sealed up for safekeeping, ultraviolet disinfection, you can.The disinfectant of the present invention has the effect of bacteriostasis and sterilization, and effect substantially, has no toxic side effect, low cost, is suitable in hospital pharmacy and the cleaning-sterilizing work in market Shang Ge great pharmacy.

Description

A kind of pharmacy disinfectant and preparation method thereof
Technical field
The present invention relates to disinfection of Chinese drug field, a kind of specifically pharmacy disinfectant and preparation method thereof.
Background technology
Pharmacy is used to the place making up a prescription and providing medicine to patient.For urgency weight that is timely, effectively treating patient Disease, hospital's often some hospital preparations of Extemporaneous.This process is often carried out in pharmacy.If the sterilizing feelings in pharmacy Condition is undesirable, then easily pathogenic bacterium are transmitted to patient.At present, most of pharmacy is disappeared using disinfectant solution or Western medicine bactericidal liquid Poison, prolongation over time, these antibacterials become and produce certain resistance, and these medicines have some abnormal flavour.Accordingly, it would be desirable to Develop new Chinese medicine anti-virus solution, to meet the needs in pharmacy, eliminate pharmacy and produced using disinfectant solution or Western medicine sterilizing The phenomenon of resistance.
Content of the invention
It is an object of the invention to provide a kind of pharmacy disinfectant and preparation method thereof, to solve in above-mentioned background technology The problem proposing.
For achieving the above object, the present invention provides following technical scheme：
A kind of pharmacy disinfectant, is prepared from by the crude drug of following weight portion：20～30 parts of Herba pteridis vittatae, Spina Gleditsiae 15 ～21 parts, 28～32 parts of Folium Artemisiae Argyi, 21～25 parts of Herba Artemisiae Annuae, 8～10 parts of Bulbus Allii, 12～16 parts of Herba Ephedrae, 11～15 parts of Fructus Viticises, Borneolum Syntheticum 10～14 parts, 10～14 parts of Fructus Cnidii, 12～16 parts of Myrrha, 6～8 parts of Semen Cuscutae.
As the further scheme of the present invention：Specifically it is prepared from by the crude drug of following weight portion：25 parts of Herba pteridis vittatae, soap 18 parts of Fructus Gleditsia acupuncture, 30 parts of Folium Artemisiae Argyi, 23 parts of Herba Artemisiae Annuae, 9 parts of Bulbus Allii, 14 parts of Herba Ephedrae, 13 parts of Fructus Viticises, 12 parts of Borneolum Syntheticum, 12 parts of Fructus Cnidii, do not have 14 parts of medicine, 7 parts of Semen Cuscutae.
A kind of preparation method of described pharmacy disinfectant, step is as follows：
(1) take Bulbus Allii to twist juice by proportioning, filter impurity, stay juice, standby；
(2) weighed Herba pteridis vittatae, Spina Gleditsiae, Folium Artemisiae Argyi, Herba Artemisiae Annuae, Bulbus Allii, Herba Ephedrae, Fructus Viticises, Borneolum Syntheticum, Fructus Cnidii, do not had by proportioning Medicine, Semen Cuscutae, clean and dry, be placed in container after chopping, add the water of crude drug gross weight 8～10 times amount to soak 5～6h, boil Boiling 2～3h, extracts；Add 6～8 times of water again, boil 1.5～2.5h, extract；Finally, add 4～6 times of water, heating is boiled Boiling 1～2h, extracts；Merge three extracting solution, filter, obtain filtrate, standby；
(3) Bulbus Allii juice is added in extracting solution, stir, filter again, filtrate fill is sealed up for safekeeping, at 55～65 DEG C Ultraviolet disinfection 20～30min, you can.
As the further scheme of the present invention：This disinfectant makes handwashing liquid, spray or dropping liquid.
Compared with prior art, the invention has the beneficial effects as follows：
The disinfectant of the present invention has the effect of bacteriostasis and sterilization, and effect substantially, has no toxic side effect, and low cost is suitable for In the cleaning-sterilizing work in hospital pharmacy and market Shang Ge great pharmacy.
Specific embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, Obviously, described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.Based in the present invention Embodiment, the every other embodiment that those of ordinary skill in the art are obtained under the premise of not making creative work, all Belong to the scope of protection of the invention.
Embodiment 1
Pharmacy disinfectant, is prepared from by the crude drug of following weight portion：20 parts of Herba pteridis vittatae, 21 parts of Spina Gleditsiae, Folium Artemisiae Argyi 28 parts, 25 parts of Herba Artemisiae Annuae, 8 parts of Bulbus Allii, 16 parts of Herba Ephedrae, 11 parts of Fructus Viticises, 14 parts of Borneolum Syntheticum, 10 parts of Fructus Cnidii, 16 parts of Myrrha, Semen Cuscutae 6 parts.
The preparation process of above-mentioned disinfectant is as follows：
(1) take Bulbus Allii to twist juice by proportioning, filter impurity, stay juice, standby；
(2) weighed Herba pteridis vittatae, Spina Gleditsiae, Folium Artemisiae Argyi, Herba Artemisiae Annuae, Bulbus Allii, Herba Ephedrae, Fructus Viticises, Borneolum Syntheticum, Fructus Cnidii, do not had by proportioning Medicine, Semen Cuscutae, clean and dry, be placed in container after chopping, add the water of crude drug gross weight 8 times amount to soak 5h, boil 2h, carry Take；Add 6 times of water again, boil 1.5h, extract；Finally, add 4 times of water, heated and boiled 1h, extract；Merge and carry for three times Take liquid, filter, obtain filtrate, standby；
(3) Bulbus Allii juice is added in extracting solution, stir, filter again, filtrate fill is sealed up for safekeeping, ultraviolet at 55 DEG C Line sterilizing 20min, makes handwashing liquid, you can.
Embodiment 2
Pharmacy disinfectant, the crude drug of following weight portion is prepared from：25 parts of Herba pteridis vittatae, 18 parts of Spina Gleditsiae, Folium Artemisiae Argyi 30 Part, 23 parts of Herba Artemisiae Annuae, 9 parts of Bulbus Allii, 14 parts of Herba Ephedrae, 13 parts of Fructus Viticises, 12 parts of Borneolum Syntheticum, 12 parts of Fructus Cnidii, 14 parts of Myrrha, Semen Cuscutae 7 Part.
The preparation process of above-mentioned disinfectant is as follows：
(1) take Bulbus Allii to twist juice by proportioning, filter impurity, stay juice, standby；
(2) weighed Herba pteridis vittatae, Spina Gleditsiae, Folium Artemisiae Argyi, Herba Artemisiae Annuae, Bulbus Allii, Herba Ephedrae, Fructus Viticises, Borneolum Syntheticum, Fructus Cnidii, do not had by proportioning Medicine, Semen Cuscutae, clean and dry, be placed in container after chopping, add the water of crude drug gross weight 9 times amount to soak 5.5h, boil 2.5h, extracts；Add 7 times of water again, boil 2h, extract；Finally, add 5 times of water, heated and boiled 1.5h, extract；Merge Three extracting solution, filter, obtain filtrate, standby；
(3) Bulbus Allii juice is added in extracting solution, stir, filter again, filtrate fill is sealed up for safekeeping, ultraviolet at 60 DEG C Line sterilizing 25min, makes spray, you can.
Embodiment 3
Pharmacy disinfectant, is prepared from by the crude drug of following weight portion：30 parts of Herba pteridis vittatae, 15 parts of Spina Gleditsiae, Folium Artemisiae Argyi 32 parts, 21 parts of Herba Artemisiae Annuae, 10 parts of Bulbus Allii, 12 parts of Herba Ephedrae, 15 parts of Fructus Viticises, 10 parts of Borneolum Syntheticum, 14 parts of Fructus Cnidii, 12 parts of Myrrha, Herba cuscutae 8 parts of son.
The preparation process of above-mentioned disinfectant is as follows：
(1) take Bulbus Allii to twist juice by proportioning, filter impurity, stay juice, standby；
(2) weighed Herba pteridis vittatae, Spina Gleditsiae, Folium Artemisiae Argyi, Herba Artemisiae Annuae, Bulbus Allii, Herba Ephedrae, Fructus Viticises, Borneolum Syntheticum, Fructus Cnidii, do not had by proportioning Medicine, Semen Cuscutae, clean and dry, be placed in container after chopping, add the water of crude drug gross weight 10 times amount to soak 6h, boil 3h, Extract；Add 8 times of water again, boil 2.5h, extract；Finally, add 6 times of water, heated and boiled 2h, extract；Merge three times Extracting solution, filters, obtains filtrate, standby；
(3) Bulbus Allii juice is added in extracting solution, stir, filter again, filtrate fill is sealed up for safekeeping, ultraviolet at 65 DEG C Line sterilizing 30min, makes dropping liquid, you can.
Experimental example bacteriostatic test
Bacteriostatic test is carried out using common filter paper enzyme in this area, wherein:
1st, material
For trying strain：Enterobacter cloacae ATCC 13047 is purchased from Shanghai Bei Nuo bio tech ltd.
Culture fluid：Nutrient agar and nutrient broth, purchased from Chen Yu experimental facilitiess company limited of BeiJing ZhongKe.
2nd, test method
Enterobacter cloacae ATCC 13047 is inoculated on agar plate nutrition fluid level, uniformly gathers during inoculation.Tweezer Aseptic circular filter paper piece, sprays the spray of preparation in embodiment, to complete wetting, is attached to the agar plate battalion of own inoculated bacteria In nutrient solution plane.Agar plate is placed in 37 DEG C of incubator, incubates 4h, the diameter of measurement antibacterial ring size, measure and be averaged for 3 times Value.
3rd, result
The inhibition zone diameter (mm) of enterobacter cloacae ATCC 13047 is 16.3mm, thus illustrating the present invention for cloaca intestinal Bacillus ATCC 13047 has certain killing action.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie In the case of the spirit or essential attributes of the present invention, the present invention can be realized in other specific forms.Therefore, no matter From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power Profit requires rather than described above limits, it is intended that all in the implication and scope of the equivalency of claim by falling Change is included in the present invention.

Claims (4)

1. a kind of pharmacy disinfectant is it is characterised in that be prepared from by the crude drug of following weight portion：Herba pteridis vittatae 20～30 Part, 15～21 parts of Spina Gleditsiae, 28～32 parts of Folium Artemisiae Argyi, 21～25 parts of Herba Artemisiae Annuae, 8～10 parts of Bulbus Allii, 12～16 parts of Herba Ephedrae, Fructus Viticises 11 ～15 parts, 10～14 parts of Borneolum Syntheticum, 10～14 parts of Fructus Cnidii, 12～16 parts of Myrrha, 6～8 parts of Semen Cuscutae.
2. pharmacy according to claim 1 disinfectant is it is characterised in that specifically prepared by the crude drug of following weight portion Form：25 parts of Herba pteridis vittatae, 18 parts of Spina Gleditsiae, 30 parts of Folium Artemisiae Argyi, 23 parts of Herba Artemisiae Annuae, 9 parts of Bulbus Allii, 14 parts of Herba Ephedrae, 13 parts of Fructus Viticises, Borneolum Syntheticum 12 parts, 12 parts of Fructus Cnidii, 14 parts of Myrrha, 7 parts of Semen Cuscutae.
3. a kind of preparation method of pharmacy as claimed in claim 1 or 2 disinfectant is it is characterised in that step is as follows：
(1) take Bulbus Allii to twist juice by proportioning, filter impurity, stay juice, standby；
(2) Herba pteridis vittatae, Spina Gleditsiae, Folium Artemisiae Argyi, Herba Artemisiae Annuae, Bulbus Allii, Herba Ephedrae, Fructus Viticises, Borneolum Syntheticum, Fructus Cnidii, Myrrha, Tu are weighed by proportioning SIZI, cleans and dries, be placed in container after chopping, adds the water of crude drug gross weight 8～10 times amount to soak 5～6h, boil 2～ 3h, extracts；Add 6～8 times of water again, boil 1.5～2.5h, extract；Finally, add 4～6 times of water, heated and boiled 1～ 2h, extracts；Merge three extracting solution, filter, obtain filtrate, standby；
(3) Bulbus Allii juice is added in extracting solution, stir, filter again, filtrate fill is sealed up for safekeeping, ultraviolet at 55～65 DEG C Line sterilizing 20～30min, you can.
4. pharmacy according to claim 3 with the preparation method of disinfectant it is characterised in that this disinfectant is made and is washed one's hands Liquid, spray or dropping liquid.
CN201610777036.XA 2016-08-31 2016-08-31 A kind of pharmacy disinfectant and preparation method thereof Pending CN106474319A (en)

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110800766A (en) * 2019-10-18 2020-02-18 贵州鼎亿生物科技有限公司 Sweet wormwood insecticide and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102552722A (en) * 2011-11-17 2012-07-11 尹华山 Traditional Chinese medicinal preparation for stopping bleeding and disinfecting
CN103120780A (en) * 2012-12-19 2013-05-29 青岛蔚蓝生物集团有限公司 Traditional Chinese medicine with disinfection function
CN105028501A (en) * 2015-08-03 2015-11-11 孔令军 Disinfectant for pharmacy

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102552722A (en) * 2011-11-17 2012-07-11 尹华山 Traditional Chinese medicinal preparation for stopping bleeding and disinfecting
CN103120780A (en) * 2012-12-19 2013-05-29 青岛蔚蓝生物集团有限公司 Traditional Chinese medicine with disinfection function
CN105028501A (en) * 2015-08-03 2015-11-11 孔令军 Disinfectant for pharmacy

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110800766A (en) * 2019-10-18 2020-02-18 贵州鼎亿生物科技有限公司 Sweet wormwood insecticide and preparation method thereof

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Application publication date: 20170308

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