CN106473787A - A kind of porous PEEK holdfast - Google Patents
A kind of porous PEEK holdfast Download PDFInfo
- Publication number
- CN106473787A CN106473787A CN201611141229.2A CN201611141229A CN106473787A CN 106473787 A CN106473787 A CN 106473787A CN 201611141229 A CN201611141229 A CN 201611141229A CN 106473787 A CN106473787 A CN 106473787A
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- CN
- China
- Prior art keywords
- holdfast
- peek
- main body
- porous peek
- porous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/064—Surgical staples, i.e. penetrating the tissue
- A61B17/0642—Surgical staples, i.e. penetrating the tissue for bones, e.g. for osteosynthesis or connecting tendon to bone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/146—Porous materials, e.g. foams or sponges
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
Abstract
The invention discloses a kind of porous PEEK holdfast, described holdfast includes main body and micropore, and described main body is made up of PEEK material, is provided with multiple described micropores on the body,, between 20% to 85%, the diameter of described micropore is between 0.1mm to 1mm for the porosity of described holdfast.The porous PEEK holdfast of the present invention, has preferable biocompatibility, and new bone growth effect is good, does not allow easy to fall off in use, and manufacture process is simple, low cost.
Description
Technical field
The present invention relates to surgical implant, more particularly, to soft tissue one of are connected porous PEEK holdfast with bone.
Background technology
Band wire holdfast is generally used for repairing soft tissue injury, by suture by the soft tissue tearing off and Bone Defect Repari, then uses anchor
The fixing suture of nail, in bone, reaches the purpose of tendon-knitting.The band wire holdfast clinically using now typically have metal anchoring nail and
Two kinds of absorbable holdfast.The poor biocompatibility of metal anchoring nail, easily produces rejection.And it can absorb holdfast in different human body
All there is larger difference in interior infiltration rate and absorbable degree, therefore surgical effect is unstable.And, both holdfasts often have
Come off, cause the situation of solid failure.
Accordingly, it is desirable to provide a kind of porous PEEK holdfast is to solve the above problems.
Content of the invention
In order to solve this problem, the invention discloses a kind of porous PEEK holdfast, described holdfast includes main body and micropore, institute
State main body to be made up of PEEK material, be provided with multiple described micropores on the body, the porosity of described holdfast arrives 20%
Between 85%, the diameter of described micropore is between 0.1mm to 1mm.
The porosity of described holdfast is preferably 30% to 50%.More preferably, the porosity of described holdfast is 40%.
It is preferred that the diameter of described micropore is between 0.4mm to 0.6mm.
It is preferred that the surface roughness of described main body is between 0.2 micron to 10 microns.
It is preferred that described main body is threaded screw shape.
It is preferred that the shape of described main body is selected from cylinder, cone or cuboid.
It is preferred that the rear end of described main body also sets up handle hole.
It is preferred that being additionally provided with through wires hole on the body, suture is connected on described holdfast.
Above-mentioned holdfast can pass through laser sintered PEEK powder, is manufactured by 3D printing.
The porous PEEK holdfast of the present invention, has preferable biocompatibility, and new bone growth effect is good, in use
Do not allow easy to fall off, manufacture process is simple, low cost.
Introduce a series of concept of reduced forms in Summary, this will specific embodiment partly in enter
One step describes in detail.Present invention part is not meant to attempt to limit the crucial special of technical scheme required for protection
Seek peace essential features, more do not mean that the protection domain attempting to determine technical scheme required for protection.
Below in conjunction with accompanying drawing, describe advantages and features of the invention in detail.
Brief description
Fig. 1 is the schematic diagram of porous PEEK holdfast according to an embodiment of the invention.
Specific embodiment
In the following description, a large amount of concrete details are given to provide more thorough understanding of the invention.So
And, it will be apparent to one skilled in the art that the present invention can one or more of these details and be able to
Implement.In other examples, in order to avoid obscuring with the present invention, some technical characteristics well known in the art are not entered
Row description.
In order to thoroughly understand the present invention, detailed structure will be proposed in following description.Obviously, the execution of the present invention is simultaneously
It is not limited to the specific details that those skilled in the art is familiar with.Presently preferred embodiments of the present invention is described in detail as follows, but
In addition to these describe in detail, the present invention can also have other embodiment.
Below in conjunction with accompanying drawing, embodiments of the invention are described in detail.
With reference to Fig. 1, it is the schematic diagram of porous PEEK holdfast according to an embodiment of the invention.The holdfast of the present invention, adopts
Manufactured with PEEK (polyether-ether-ketone).PEEK material has excellent biocompatibility and mechanical property, can be chronically implanted human body
And do not cause human body to repel.PEEK density of material is low, and the PEEK material of porous more can reduce the quality of implant, in addition,
The elastic modelling quantity of PEEK material, close to human Cortex's bone, can be good at stimulating osteanagenesis.
The porous PEEK holdfast of the present invention includes main body 1, and in FIG, main body 1 is threaded screw shape.Due to adopting
With the shape of screw, when using, without punching in advance, can directly pierce.But it is understood that, the present invention's is many
The shape not limited to this of the main body 1 of hole PEEK holdfast, it would however also be possible to employ other shapes, such as cylinder, cone, cuboid
Deng.When there is no the main body of self tapping effect using other it may be necessary to punch in advance in implant site.
In the rear end of main body 1, handle hole can also be set.Handle hole can combine with other utensils, is sent holdfast with facilitating
Enter position to be implanted.It is additionally provided with through wires hole on the body 1, suture is connected on holdfast.
It is provided with multiple micropores 2 on the body 1, the porous PEEK holdfast of the present invention can be good at inducing new bone in holdfast
Surface and tumor growth.
For the setting of micropore, if the quantity of setting is excessive, the overall intensity of holdfast can be affected, if the quantity of setting
Very few, then telling on of new bone can be made not good.Therefore, select suitable porosity particularly important.It is total that porosity is hole
Volume accounts for the ratio of small product size.Its calculation is as follows：
In formula：P is porosity (%), drFor material actual density (g/cm3), dthFor materials theory density (g/cm3).
Through overtesting, it has been found that the selection of porosity can obtain preferably new bone life between 25%-85%
Long.Test is as follows：
1. adopt 3D printing PEEK technology, using laser sintered PEEK powder, produce the porous PEEK holdfast of the present invention.
The length of holdfast is 9mm, a diameter of 5mm at screw thread, a diameter of 3mm at non-threaded, and pore diameter is chosen as 0.5mm.Above-mentioned
Under parameter identical parameter, prepare respectively porosity be 25%, 30%, 40%, 50%, 85% holdfast.
2. subjects adopt healthy adult domesticated dog, and body weight is about 13 kilograms.It is divided into five groups, every group 4.Wherein A group is adopted
The holdfast being 25% with porosity, B group porosity is 30%, C group porosity is 50%, E group hole for 40%, D group porosity
Rate is 85%.
3. above-mentioned subjects are manufactured Cranial defect, defect area and holdfast size one in condylus lateralis femorises centre
Cause.Implantation holdfast finishes rear sewing-up cut.
4., after performing the operation 3 months, take subjects condylus lateralis femorises specimen.Freshman bone tissue at Cranial defect is carried out with quantitative point
Analysis.Calculation is：
Gross area x100% in N=osseous tissue area/visual field.
Wherein N is freshman bone tissue's area ratio.
When carrying out quantitative analyses, image acquisition can be carried out using the full microscope on market, and pass through image
Analysis software (such as Image pro etc.) carries out quantitative analyses.Result is as follows：
It can be seen from the results above that porosity is higher, then the growth of new bone is better, and the setting that micropore is described is really to new
The growth of bone is effective.Therefore, if do not considered the factors such as intensity, the higher holdfast of porosity can be selected.But, if porosity
Too high, then intensity is affected.It is therefore advantageous to, porosity selects in 30%-50%.More excellent is chosen as 40%.
The aperture of above-mentioned micropore 2 can select between 0.1mm-1mm.Preferably, aperture is 0.4mm-0.6mm.
In addition, for the adhesion promoting platelet attachment and fibrin block, providing initial stablizing for getting up early bone formation
Environment, roughness R on the surface of the holdfast in the present inventionaSelect more than 0.2 micron and be less than 10 microns.
As described above, the preparation of the holdfast of the present invention can adopt laser sintered 3D printing PEEK technology, burnt using laser
Knot PEEK powder, " printing " goes out porous PEEK holdfast.The preparation of the holdfast of the present invention only need to use PEEK powder, compared to PEEK
Section bar, the cost of powder substantially reduces, and is lost low.And preparation process does not need to add pore creating material, clear thus without occurring
The clean pollution totally not caused is topic, and process is simple, low cost.
The porous PEEK holdfast of the present invention, has preferable biocompatibility, and new bone growth effect is good, in use
Do not allow easy to fall off, manufacture process is simple, low cost.
The present invention is illustrated by above-described embodiment, but it is to be understood that, above-described embodiment is only intended to
Citing and descriptive purpose, and be not intended to limit the invention in described scope of embodiments.In addition people in the art
Member, it is understood that the invention is not limited in above-described embodiment, can also make more kinds of according to the teachings of the present invention
Variants and modifications, within these variants and modifications all fall within scope of the present invention.Protection scope of the present invention by
The appended claims and its equivalent scope are defined.
Claims (10)
1., it is characterised in that described holdfast includes main body and micropore, described main body is by PEEK material system for a kind of porous PEEK holdfast
Become, be provided with multiple described micropores on the body, the porosity of described holdfast between 20% to 85%, described micropore
Diameter is between 0.1mm to 1mm.
2. according to the porous PEEK holdfast described in claim 1 it is characterised in that the porosity of described holdfast preferably 30% arrives
50%.
3. according to the porous PEEK holdfast described in claim 1 it is characterised in that the porosity of described holdfast is 40%.
4. according to the porous PEEK holdfast described in claim 1 it is characterised in that the diameter of described micropore is in 0.4mm to 0.6mm
Between.
5. according to the porous PEEK holdfast described in claim 1 it is characterised in that the surface roughness of described main body is micro- 0.2
Rice is between 10 microns.
6. according to the porous PEEK holdfast any one of claim 1-5 it is characterised in that described main body is threaded
Screw shape.
7. according to the porous PEEK holdfast any one of claim 1-5 it is characterised in that the shape of described main body is selected from
Cylinder, cone or cuboid.
8. according to the porous PEEK holdfast any one of claim 1-5 it is characterised in that the rear end of described main body also sets
Put handle hole.
9. according to the porous PEEK holdfast described in claim 8 it is characterised in that being additionally provided with threading on the body
Hole, suture is connected on described holdfast.
10. porous PEEK holdfast according to claim 1 is it is characterised in that described holdfast passes through laser sintered PEEK powder
End, is manufactured by 3D printing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611141229.2A CN106473787A (en) | 2016-12-12 | 2016-12-12 | A kind of porous PEEK holdfast |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611141229.2A CN106473787A (en) | 2016-12-12 | 2016-12-12 | A kind of porous PEEK holdfast |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106473787A true CN106473787A (en) | 2017-03-08 |
Family
ID=58284714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611141229.2A Pending CN106473787A (en) | 2016-12-12 | 2016-12-12 | A kind of porous PEEK holdfast |
Country Status (1)
| Country | Link |
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| CN (1) | CN106473787A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10575886B2 (en) | 2018-05-09 | 2020-03-03 | Warsaw Orthopedic, Inc. | Bone screw and method of manufacture |
| US10993753B2 (en) | 2018-05-09 | 2021-05-04 | Warsaw Orthopedic, Inc. | Bone screw and method of manufacture |
| US11191582B2 (en) | 2018-05-09 | 2021-12-07 | Warsaw Orthopedic, Inc. | Bone screw and method of manufacture |
| US11224470B2 (en) | 2018-05-09 | 2022-01-18 | Warsaw Orthopedic, Inc. | Bone screw and method of manufacture |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10575886B2 (en) | 2018-05-09 | 2020-03-03 | Warsaw Orthopedic, Inc. | Bone screw and method of manufacture |
| US10993753B2 (en) | 2018-05-09 | 2021-05-04 | Warsaw Orthopedic, Inc. | Bone screw and method of manufacture |
| US11191582B2 (en) | 2018-05-09 | 2021-12-07 | Warsaw Orthopedic, Inc. | Bone screw and method of manufacture |
| US11224470B2 (en) | 2018-05-09 | 2022-01-18 | Warsaw Orthopedic, Inc. | Bone screw and method of manufacture |
| US11589907B2 (en) | 2018-05-09 | 2023-02-28 | Warsaw Orthopedic, Inc. | Bone screw and method of manufacture |
| US11857233B2 (en) | 2018-05-09 | 2024-01-02 | Warsaw Orthopedic, Inc. | Bone screw and method of manufacture |
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