CN106422073A - Rectal cancer photodynamic therapy mini-type LED illumination source based on wireless power supply - Google Patents
Rectal cancer photodynamic therapy mini-type LED illumination source based on wireless power supply Download PDFInfo
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- CN106422073A CN106422073A CN201610517363.1A CN201610517363A CN106422073A CN 106422073 A CN106422073 A CN 106422073A CN 201610517363 A CN201610517363 A CN 201610517363A CN 106422073 A CN106422073 A CN 106422073A
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- circuit
- resonance
- current
- led illumination
- mini
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
- A61N5/0603—Apparatus for use inside the body for treatment of body cavities
- A61N2005/0608—Rectum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/065—Light sources therefor
- A61N2005/0651—Diodes
Abstract
The present invention discloses a rectal cancer photodynamic therapy mini-type LED illumination source based on wireless power supply. The source comprises bullet-shaped housing, the housing is internally provided a voltage regulator module and a LED light source with the wavelength range of 630-650nm, the housing is internally provided with a LC resonance matching receiving coil and a first rectification filter circuit, the LC resonance matching receiving coil is 20*5*2mm, and the inductance value is 60[Mu]H; the mini-type LED illumination source also comprises an electric power emission unit consisting of a current generation current and a LC resonance matching sending coil; and the current generation circuit is configured to generate alternating current to allow the LC resonance matching sending coil to generate resonance. The Rectal cancer photodynamic therapy mini-type LED illumination source based on the wireless power supply can obtain electric energy at any moment so as to solve the power supply problem in the rectal suppository therapy and enhance the reliability of the rectal suppository. The contradictions of the mini-type implantable medical device power supply and the small size, and the attention of medical staff to the rectal suppository electric quantity is saved, and a condition is created for the product clinical expansion.
Description
Technical field
The invention belongs to laser radiation source design field in optical dynamic therapy research, relate to a kind of implantable intrarectal
Miniature LED illumination light source based on wireless power technology.
Background technology
The carcinoma of the rectum (colorectal cancer, CRC) is initiated by rectal mucosal malignant tumour, be digestive system
One of common malignant tumour, its death rate is higher and the incidence of disease is rising year by year.Owing to early symptom is not true to type, cause in early days
Diagnose relatively difficult.It when clinical symptoms occurs in Most patients, has been in middle and advanced stage.In recent years, as colorectal cancer molecule is raw
The progress of thing, its treatment is not limited solely to the conventional methods such as conventional operation, radiotherapy, chemotherapy, the treatment of the carcinoma of the rectum
Pattern is changing, but its 5 years survival rates are not still high.With universal, the laser instrument of fibro-colonoscope and changing of sensitising agent
Entering, PDT (photodynamic therapy, PDT) treatment colorectal cancer is more and more paid attention to, and at knot
Rectum cancer treatment achieves promising result.
PDT is a kind of disease treatment new tool as general principle that interacts with light, sensitising agent and oxygen,
Its treatment principle is：After giving a certain amount of sensitising agent of body, sensitising agent is excited to occur through the illumination of specific wavelength a series of photochemical
Learning reaction, pathological tissues just can produce has Cytotoxic active oxygen (such as singlet oxygen, oxygen radical etc.), is made by oxidation
With, the structure of destruction organelle and function, cause sick cell apoptosis and necrosis, thus reach to treat the purpose of tumour.It is made
Mainly there are three aspects by mechanism：(1) active oxygen inducing cell apoptosis and necrosis, direct killing tumour cell；(2) destroy tumour to nourish
Blood vessel, causes tumor ischemia anoxic；(3) promote the release of inflammatory mediator, start immune response, lead oncogenic destruction.Light power
Treatment is due to advantages such as its wound are little, toxicity is low, targeting is strong, applicability is wide, repeatable, gradually by increasing patient institute
Accept.
Implanted rectal plug light source power supply mode for carcinoma of the rectum optical dynamic therapy can be divided into lithium battery and wireless confession
Electricity.Lithium battery power supply is due to volumetric constraint, and electricity is less, it is impossible to support long-term stable operation.
Wireless power technology refers to utilize electromagnetic wave induction principle or other related alternating current impression technology, at transmitting terminal
Send with the corresponding equipment of receiving terminal and receive and produce the technology that the AC signal of sensing is charged, come from nothing
Line electric power conveying technology.Current wireless charging technology mainly has three kinds of basic modes, and one is electromagnetic coupled induction type, transmits the upper limit
It is about 10cm, be primarily adapted for use in short range electric power transmission.Electromagnetic coupled induction type is to utilize electromagnetic induction principle, at transmitting terminal and
Receiving terminal is respectively arranged with a coil, sends the alternating current of logical certain frequency on coil, owing to electromagnetic induction produces in receiving coil
Certain electric current, thus energy is transferred to receiving terminal from transmission end.This wireless charging mode charge efficiency is higher, but fills
Electrical distance is little, needs specific putting position accurately to charge.Two is magnet coupled resonant type, and transmission range can reach 10m, mainly fits
For medium or short range electric power transmission.Magnet coupled resonant type makes transmitting and receiving device have phase by the reasonable computation of coil and electric capacity
Same resonant frequency, when system works under this frequency, launches and receiving coil generation resonance, completes the transmission of electric energy.It is former
Manage identical with the resonance principle of sound, the coil of the identical vibration frequency being arranged in magnetic field, can be from one to another power supply.
This mode has farther transmission range than simple magnetic coupling charging system, and logical barrier property is more preferable, launches and accepts dress
Barrier between putting is little on the impact of device, is suitable for moderate distance charging.Three is wave radiation formula, is primarily adapted for use in big model
Enclose, the remote transmission of distance.This circulation way of wave radiation formula mainly utilizes energy to change, by microwave source equipment to directly
Stream electricity carries out transformation and becomes microwave or laser；By antenna, microwave is transmitted into free space, and the equipment that is received turns again
Become direct current.
Content of the invention
The invention provides the miniature LED illumination light source of a kind of carcinoma of the rectum optical dynamic therapy based on wireless power, this is micro-
Type LED illumination light source is an implant, carries out wireless power by resonant coupling techniques to implant, it is provided that low for a long time
The carcinoma of the rectum light power light source of dosage, has voltage stabilization, wireless charging, the convenient feature of switch control rule under duty.
In order to solve above-mentioned technical problem, a kind of carcinoma of the rectum optical dynamic therapy based on wireless power of present invention proposition
Miniature LED illumination light source, including housing, described housing is bullet-shaped, and uses medical epoxide resin material to make；Described shell
It internal is provided with Voltage stabilizing module and the LED light source that wave-length coverage is 630nm-650nm, be additionally provided with LC resonance coupling in described housing and connect
Take-up circle, the first current rectifying and wave filtering circuit, it is 60 that described LC resonance coupling receives the long 20mm of coil, wide 5mm, thick 2mm and inductance value
μH；, described first current rectifying and wave filtering circuit is the high-frequency rectification circuit between 10KHz-1MHz；
This miniature LED illumination light source also includes power transmission unit, described power transmission unit by current occuring circuit and
LC resonance coupling transmitting coil is constituted；Described current occuring circuit is used for producing alternating current and makes described LC resonance coupling launch line
Circle resonance；The ac frequency that described current occuring circuit produces is connect by described LC resonance coupling transmitting coil and LC resonance coupling
The resonance circuit parameter of take-up circle determines；Described LC resonance coupling transmitting coil mates reception coil and has identical humorous with LC resonance
Vibration frequency.
Further, the present invention is based on the miniature LED illumination light source of the carcinoma of the rectum optical dynamic therapy of wireless power, wherein,
Described current occuring circuit includes that the second current rectifying and wave filtering circuit, DC chopper circuit and the full-bridge inverting that are sequentially connected with civil power drive
Dynamic circuit, is connected with an overcurrent overheat testing circuit and a power conditioning circuitry simultaneously, and described DC chopper circuit is according to output
Load power demand is by the DC voltage of described power conditioning circuitry control full-bridge inverting drive circuit input, and described mistake is flowed
Overheating detection circuit carries out overcurrent overheat detection according to the feedback current that described DC chopper circuit exports；Described full-bridge inverting drives
Dynamic circuit is connected with described LC resonance coupling transmitting coil, and by a frequency-tracking inverter control circuit according to described LC resonance
The frequency of the feedback current control described full-bridge inverting drive circuit output electric current of coupling transmitting coil；Described second rectifying and wave-filtering
Circuit is industrial frequency rectifying filter circuit.
Compared with prior art, the invention has the beneficial effects as follows：
(1) light source of the present invention is based on wireless charging, can keep burning voltage at any time, it is not necessary to use battery, does not exist and needs
The problem of battery electric quantity to be monitored.
(2) light source of the present invention is based on wireless power technology, can obtain electric energy at any time in the rectal plug course of work, exempts
The secondary implant procedure of rectal plug；Meanwhile, eliminate the charging operations of medical worker, simplify use process, it is ensured that be straight
Intestines bolt continuity over the course for the treatment of.
(3) switch of light source of the present invention can be easy and simple to handle and enhance straight by external power transmission unit control
Intestines bolt controllability over the course for the treatment of.
Brief description
Fig. 1 is the frame diagram based on the miniature LED illumination light source of the carcinoma of the rectum optical dynamic therapy of wireless power for the present invention；
Fig. 2 is the specific embodiment frame diagram of current occuring circuit in Fig. 1；
Fig. 3 is the structural representation based on the miniature LED illumination light source of the carcinoma of the rectum optical dynamic therapy of wireless power for the present invention
Figure.
Detailed description of the invention
Below by detailed description of the invention, being described in further detail the foregoing of invention, embodiment is only and solves
The property released, by no means imply that it limits the scope of the present invention by any way.But without departing from the idea case in the present invention described above,
It according to the modification of the various replacements change alive that ordinary skill knowledge and usual means are made, is included in the present invention's
In the range of.
The miniature LED illumination light source of a kind of carcinoma of the rectum optical dynamic therapy based on wireless power of the present invention, including external body
Divide and internal body portion.
Internal body portion includes housing 7, as it is shown on figure 3, described housing 7 is bullet-shaped, and uses medical epoxy resin material
Material is made, and for example with medical transparent plastic, as shown in figures 1 and 3, is provided with LC resonance coupling and receives coil in described housing 7
3rd, the first current rectifying and wave filtering circuit 4, Voltage stabilizing module 5 and wave-length coverage are the LED light source 6 of 630nm-650nm, of internal body portion
Instantiation is：By the one-time formed bullet-shaped medical transparent shell being about 2.5cm, diameter about 1cm of mould, this housing
7 employing epoxide resin materials are made, and ensureing organization security, and are easy to moulding, and the transparent effect playing printing opacity of material helps
In reduction light loss, and the shape of bullet-shaped suppository can improve the compliance of patient, also more convenient on using.LC resonance
Connecting take-up circle 3 and being designed as ellipse, long 20mm, wide 6mm, thick 2mm, inductance value is 60 μ H, and shape adapts with mould, and full
Foot rectal plug normal operating power, described LED light source 6 is made up of 1 adopting surface mounted LED, it is possible to achieve light power is maximum
30mW, spot size is about 1cm2.In this housing 7, sealed bundle is wrapped with above-mentioned device and circuit, i.e. with a circuit board bearing and company
Connect above-mentioned device and circuit, then, whole circuit board is put into bullet-shaped housing 7, carries out epoxy encapsulation, 1-2
After its solidification, remove mould, i.e. form internal body portion.
Outer body is a power transmission unit, receives coil 3 for mating the LC resonance coupling in above-mentioned internal body portion
Sensing produces electric energy and powers to rectal plug.As it is shown in figure 1, described power transmission unit is by current occuring circuit 1 and LC resonance
Join transmitting coil 2 to constitute；As in figure 2 it is shown, described current occuring circuit 1 is used for producing alternating current, described LC resonance coupling is sent out
Ray circle 2 resonance；Described current occuring circuit 1 includes the second current rectifying and wave filtering circuit the 12nd, the DC chopped-wave being sequentially connected with civil power
Circuit 13 and full-bridge inverting drive circuit 14, with an overcurrent overheat testing circuit 16 and a while described DC chopper circuit 13 is gone back
Power conditioning circuitry 15 is connected, and described DC chopper circuit 13 passes through described power conditioning circuitry according to output loading power requirement
The DC voltage of 15 control full-bridge inverting drive circuit 14 inputs；Described full-bridge inverting drive circuit 14 and described LC resonance
Join transmitting coil 2 to connect, and mate the anti-of transmitting coil 2 by a frequency-tracking inverter control circuit 17 according to described LC resonance
The described full-bridge inverting drive circuit 14 of supply current control exports the frequency of electric current.
In the present invention, described first current rectifying and wave filtering circuit 4 is the high-frequency rectification circuit between 10KHz-1MHz；Described second
Current rectifying and wave filtering circuit 12 is industrial frequency rectifying filter circuit.(external) described LC resonance coupling in described power transmission unit is sent out
Ray circle 2 mates reception coil 3 with (internal) the LC resonance in housing 7 identical resonance frequency, and described LC resonance coupling connects
The change in magnetic field in take-up circle 3 inductive spacing, produces the alternating current of respective change, and alternating current is by the first rectifying and wave-filtering electricity
AC signal is converted into corresponding DC current signal by road 4 and Voltage stabilizing module 5, provides constant voltage for LED light source 6,
Stabilize it luminescence.
To sum up, the present invention utilizes magnetic coupling resonance principle wireless type energy supply, is existed by the switch of external power transmission unit
The external switch controlling rectal plug, easy to control, owing to eliminating the on-off circuit on power-supply device and rectal plug, reduce body
The volume of interior part (rectal plug), raising key repeat usage；Can eliminate and repeatedly charge in the treatment with filling
Step, solves the powerup issue in rectal plug treatment, not only alleviates the work of medical worker, and avoid battery electric quantity
The awkward situation exhausting.It is the LED between 630nm-650nm that light source in the present invention uses single wave-length coverage, and penetration power is strong, spoke
Show up little, can be precisely controlled, and irradiated region dose of radiation is uniform.Compared with similar products, the light source using the present invention can letter
Change the OPK therapeutic process of the carcinoma of the rectum, enhance the reliability of rectal plug.Technical solution of the present invention solves miniature implanted
Power supply of medical equipment is powered and the contradiction between small size, and solve medical worker over the course for the treatment of will be at any time to rectum simultaneously
The problem of bolt electricity concern, is that miniature implantable medical device product especially carries out low-yield for a long time holding in patient's rectum
The clinical expansion of continuous optical dynamic therapy product creates condition.
Claims (2)
1. the miniature LED illumination light source of carcinoma of the rectum optical dynamic therapy based on wireless power, including housing (7), described shell
Body (7) is bullet-shaped, and uses medical epoxide resin material to make；It is provided with Voltage stabilizing module (5) and wavelength in described housing (7)
LED light source (6) between 630nm-650nm scope, it is characterised in that：
It is additionally provided with LC resonance coupling in described housing (7) and receive coil (3), the first current rectifying and wave filtering circuit (4), described LC resonance
Connecting the long 20mm of take-up circle (3), wide 5mm, thick 2mm, and inductance value is 60 μ H, and described first current rectifying and wave filtering circuit (4) is
High-frequency rectification circuit between 10KHz-1MHz；
This miniature LED illumination light source also includes power transmission unit, and described power transmission unit is by current occuring circuit (1) and LC
Resonance coupling transmitting coil (2) is constituted；Described current occuring circuit (1) is used for producing alternating current and described LC resonance coupling is sent out
Ray circle (2) resonance；The ac frequency that described current occuring circuit (1) produces is by described LC resonance coupling transmitting coil (2)
The resonance circuit parameter receiving coil (3) with LC resonance coupling determines；
Described LC resonance coupling transmitting coil (2) mates reception coil (3) and has identical resonance frequency with LC resonance.
2. according to claim 1 based on the miniature LED illumination light source of carcinoma of the rectum optical dynamic therapy of wireless power, its feature
It is：Described current occuring circuit (1) includes the second current rectifying and wave filtering circuit (12), the DC chopper circuit being sequentially connected with civil power
(13) and full-bridge inverting drive circuit (14), described DC chopper circuit (13) simultaneously with an overcurrent overheat testing circuit (16) and
One power conditioning circuitry (15) is connected, and described DC chopper circuit (13) is adjusted by described power according to output loading power requirement
The DC voltage of economize on electricity road (15) control full-bridge inverting drive circuit (14) input, described overcurrent overheat testing circuit (16) root
The feedback current exporting according to described DC chopper circuit (13) carries out overcurrent overheat detection；Described full-bridge inverting drive circuit (14)
It is connected with described LC resonance coupling transmitting coil (2), and humorous according to described LC by a frequency-tracking inverter control circuit (17)
The frequency of feedback current control described full-bridge inverting drive circuit (14) the output electric current of coupling transmitting coil (2) of shaking；Described
Two current rectifying and wave filtering circuits (12) are industrial frequency rectifying filter circuit.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610517363.1A CN106422073A (en) | 2016-06-30 | 2016-06-30 | Rectal cancer photodynamic therapy mini-type LED illumination source based on wireless power supply |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610517363.1A CN106422073A (en) | 2016-06-30 | 2016-06-30 | Rectal cancer photodynamic therapy mini-type LED illumination source based on wireless power supply |
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| CN106422073A true CN106422073A (en) | 2017-02-22 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610517363.1A Pending CN106422073A (en) | 2016-06-30 | 2016-06-30 | Rectal cancer photodynamic therapy mini-type LED illumination source based on wireless power supply |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107874901A (en) * | 2017-10-26 | 2018-04-06 | 杨铭轲 | Contact lens and intraocular illuminator |
| CN109471393A (en) * | 2018-11-22 | 2019-03-15 | 广州龙之杰科技有限公司 | A kind of device and method in security control magnetic field |
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| US20080121825A1 (en) * | 2005-01-18 | 2008-05-29 | Koninklijke Philips Electronics, N.V. | Electronically Controlled Capsule For Releasing Radiation |
| CN203989504U (en) * | 2014-04-10 | 2014-12-10 | 深圳普门科技有限公司 | There is capsule photon therapy device, the system of guide function |
| CN205924723U (en) * | 2016-06-30 | 2017-02-08 | 中国医学科学院生物医学工程研究所 | Miniature LED radiation source of carcinoma of rectum light power treatment based on wireless power supply |
-
2016
- 2016-06-30 CN CN201610517363.1A patent/CN106422073A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080121825A1 (en) * | 2005-01-18 | 2008-05-29 | Koninklijke Philips Electronics, N.V. | Electronically Controlled Capsule For Releasing Radiation |
| CN203989504U (en) * | 2014-04-10 | 2014-12-10 | 深圳普门科技有限公司 | There is capsule photon therapy device, the system of guide function |
| CN205924723U (en) * | 2016-06-30 | 2017-02-08 | 中国医学科学院生物医学工程研究所 | Miniature LED radiation source of carcinoma of rectum light power treatment based on wireless power supply |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107874901A (en) * | 2017-10-26 | 2018-04-06 | 杨铭轲 | Contact lens and intraocular illuminator |
| CN109471393A (en) * | 2018-11-22 | 2019-03-15 | 广州龙之杰科技有限公司 | A kind of device and method in security control magnetic field |
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Application publication date: 20170222 |
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