CN106421289A - Unguent for treating herpes zoster and preparing method thereof - Google Patents
Unguent for treating herpes zoster and preparing method thereof Download PDFInfo
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- CN106421289A CN106421289A CN201610965601.5A CN201610965601A CN106421289A CN 106421289 A CN106421289 A CN 106421289A CN 201610965601 A CN201610965601 A CN 201610965601A CN 106421289 A CN106421289 A CN 106421289A
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Abstract
The invention relates to unguent for treating herpes zoster. The unguent is prepared from, by weight, 22-80 parts of schizonepeta, 19-70 parts of tribulus terrestris L, 19-70 parts of forsythia suspensa, 19-70 parts of radices trichosanthis,16-55 parts of coptis chinensis, 16-55 parts of scutellaria baicalensis, 16-55 parts of golden cypress, 16-50 parts of realgar, 16-50 parts of rheum officinale, 14-50 parts of rhizoma pinelliae, 14-50 parts of the root bark of the peony tree, 11-40 parts of seed of feather cockscomb, 11-40 parts of indigo naturalis, 8-30 parts of poria cocos, 8-30 parts of lemna minor, 8-30 parts of paris polyphylla, 8-30 parts of dried alum, 8-30 parts of scorpio, 7-25 parts of lumbricus, 7-20 parts of divaricate saposhnikovia root, 7-20 parts of cornu bubali, 7-20 parts of periostracum cicada, 5-15 parts of glycyrrhiza uralensis and 5-15 parts of borneol. The invention also discloses a preparing method of the unguent for treating herpes zoster. The formula of the unguent for treating herpes zoster has the advantages that medicinal herbs resources are wide, materials are easy to obtain, the unguent is convenient to use, medicinal effects are quick, time and money are saved and the like. Besides, the adoption of cream-type unguent guarantees that the unguent is not prone to tainting of clothes.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine preparation is and in particular to a kind of ointment treating herpes zoster and its preparation side
Method.
Background technology
Herpes zoster (herpes zoster) is the one kind being caused by varicella zoster virus infection with along surrounding god
Cluster herpess through distribution and the viral dermatosiies that are characterized of neuralgia are popular in spring.The morbidity portion of herpes zoster
Position more than 60% is in breast loin, therefore among the people and have " herpes zoter around waist ", being commonly called as of " herpes zoster ".Modern medicine thinks this disease
It is that varicella zoster viruss are invaded in vivo by respiratory tract infection, hide in spinal nerves or other neural neurocytes.This disease
Poison can not be fallen ill at ordinary times, but because old people and weakly people's immunity reduce, is running into fatigue, flu
When, easily induce herpes zoster.
Chinese medicine thinks that herpes zoster is that impression poison is evil, wet, heat, wind, and fire stagnation intercepts in the heart, liver, lung, spleen, meridians, QI and blood
Stagnate and form.Because of feelings will internal injury, conscience heat resulting from stagnation of QI, heat stagnation fire-transformation long, intimately overflow in flesh table, flee meridians, then feel wind, fire
Evil poison, makes QI and blood closing, erythema, mound scar rash, the diseases such as pain of itching；Dysfunction of the spleen in transportation and life is wet, wet the penting up of spleen and change heat, damp and hot outer
Send out skin, then feel toxic dampness and heat, so that a surname of lung is sent out, respectful fall, control section dysfunction, cause aqueous to follow meridians and close and gather in flesh table, then see
The innumerable such as pearl of water lump：Damp and hot wind-fire evil poison, damages meridians, does not declare through gas, stagnation of QI blood addiction, stagnation of QI and blood may bring about pain, often cause pain endlessly or
Twinge is continuous.Therefore, Chinese traditional treatment indomethacin is divided into：Ascites of liver meridian damp-heat type；Spleen and stomach damp-heat type；Stagnation of QI blood addiction type etc., dialectical controls
Treatment obtains good curative effect, and does not recur.
After banding virus infection with latent form long-term existence in the ganglionic cell of spinal nerves or cranial nerve, work as body
When immunologic function weakens, varicella zoster virus activity growth and breeding can be induced, involve skin along peripheral nerve, banding occurs
Herpess.Before morbidity usually heating, weak, general malaise, inappetence, regional nodeses swell and ache and illing skin burns
Heat, hyperesthesia or neuralgia etc., the foxtail millet grain not merged therewith cluster occurs to the big pimple of Semen Glyciness, pimple is changed into water then
Bleb, limpid vesicle fluid, tonic vesicle wall, encloses with blush.Skin lesion circumferentially Substance P, arrangement becomes band.
The clinical manifestation of herpes zoster：Classical symptom often has slight General Symptomies before occurring, such as low grade fever, asthenia, whole body
Discomfort, inappetence etc., the area skin that will appear from erythra shortly is uncomfortable, and whole body or local forerunner's disease in local pain
After shape 1-4 day, skin occur cluster if foxtail millet is to the big vesicle of Semen phaseoli radiati or blood blister rash, limpid vesicle fluid or blood blister, walk along nerve
To in zonation, substrate often around with blush, is usually no more than torso midline, is common in intercostal nervess, cervical neural, trident god
Warp and waist sacrum innervation area, such as face, neck, thoracic dorsal, waist and belly, also can invade eye, ear, oral cavity and pudendum mucosa, neuralgia
One of feature of primary disease, can occur before erythra or with erythra occur, some patientss after deflorescence, sustainable number
The moon or more long.The erythra of Head And Face can involve cornea, causes viral keratitiss.Also facial paralysis, otalgia, external auditory meatus bleb can be caused
Rash three is levied, and claims Ransey-Hunt syndrome, severe patient can be with hyperpyrexia, pneumonia, encephalitis etc..
The histopathology of herpes zoster：Similar to the pathological changes of herpes simplex, but inflammatory reaction is heavier.
The Diagnosis and differential diaggnosis of herpes zoster：Herpes zoster, according to cluster phlysis, moves towards unilateral distribution along nerve, has
Significantly neuralgia, general diagnostic is not difficult, should be with herpes simplex, and impetigo differentiates, bleb bottom or hydrocrania are separated to virus etc. and have
Help make a definite diagnosis.
At present, the medicine for the treatment of herpes zoster is a lot, is roughly divided into oral and external two big class, general treatment herpes zoster
Principle be to utilize antiviral treatment, and the traditional Chinese medical science thinks that herpes zoster is mainly sent out in costa sternaless or waist, is belonging to " skirt-roof fire
Red " or it is also called " herpes zoster ", its treatment should take the cool heart to let out liver according to its symptom respectively, and dissipating rashes removing toxic substances or lung heat clearing purgation of spleen excess remove
Wet, eliminating toxic substances to remove stasis, removing obstruction in the collateral to relieve pain, liniment, treating both the principal and secondary aspects of a disease.Medicine for external use is the requisite medicine for the treatment of herpes zoster,
Good medicine for external use can prevent and treat the neuralgic generation of herpess sequela.If any the ointment of a kind of " acyclovir ", using effect is relatively
Good, but have patient with after have anaphylaxiss, cause course of disease prolongation, cause great misery to patient.
Content of the invention
It is an object of the invention to：For above-mentioned deficiency, the invention provides a kind of medicine treating herpes zoster
Cream and preparation method thereof.Prescription of the present invention has medicine source widely, draws materials easily, easy to use, and drug effect is rapid, saves time economical etc. all
Many advantages, using cream form, are difficult pollution clothes.
In order to achieve the above object, present invention employs technical scheme below：
A kind of ointment treating herpes zoster, is made up of the raw material of Chinese medicine of following weight portion：22～80 parts of Herba Schizonepetae, Fructus Atriplicis Sibiricae 19～
70 parts, 19～70 parts of Fructus Forsythiae, 19～70 parts of Radix Trichosanthis, 16～55 parts of Rhizoma Coptidis, 16～55 parts of Radix Scutellariae, 16～55 parts of Cortex Phellodendri, Realgar
16～50 parts, 16～50 parts of Radix Et Rhizoma Rhei, 14～50 parts of Rhizoma Pinelliae Preparata, 14～50 parts of Cortex Moutan, 11～40 parts of Semen Celosiae, 11～40 parts of Indigo Naturaliss,
8～30 parts of Poria, 8～30 parts of Herba Spirodelae, 8～30 parts of Rhizoma Paridis, 8～30 parts of dried Alumen, 8～30 parts of Scorpio, 7～25 parts of Pheretima, Radix Saposhnikoviae 7
～20 parts, 7～20 parts of Cornu Bubali, 7～20 parts of Periostracum Cicadae, 5～15 parts of Radix Glycyrrhizae and 5～15 parts of Borneolum Syntheticum.
Currently preferred technical scheme is, a kind of described ointment treating herpes zoster, by following weight portion
Medicine raw material is made：37～65 parts of Herba Schizonepetae, 34～55 parts of Fructus Atriplicis Sibiricae, 34～55 parts of Fructus Forsythiae, 34～55 parts of Radix Trichosanthis, Rhizoma Coptidis 31～40
Part, 31～40 parts of Radix Scutellariae, 31～40 parts of Cortex Phellodendri, 31～35 parts of Realgar, 31～35 parts of Radix Et Rhizoma Rhei, 29～35 parts of Rhizoma Pinelliae Preparata, Cortex Moutan 29～
35 parts, 21～30 parts of Semen Celosiae, 21～30 parts of Indigo Naturaliss, 18～20 parts of Poria, 18～20 parts of Herba Spirodelae, 18～20 parts of Rhizoma Paridis, dried Alumen
18～20 parts, 18～20 parts of Scorpio, 12～20 parts of Pheretima, 12～15 parts of Radix Saposhnikoviae, 12～15 parts of Cornu Bubali, 12～15 parts of Periostracum Cicadae,
8～12 parts of Radix Glycyrrhizae and 8～12 parts of Borneolum Syntheticum.
Further, a kind of described ointment treating herpes zoster, is made up of the raw material of Chinese medicine of following weight portion：Herba Schizonepetae
51 parts, 45 parts of Fructus Atriplicis Sibiricae, 45 parts of Fructus Forsythiae, 45 parts of Radix Trichosanthis, 35 parts of Rhizoma Coptidis, 35 parts of Radix Scutellariae, 35 parts of Cortex Phellodendri, 33 parts of Realgar, Radix Et Rhizoma Rhei
33 parts, 32 parts of Rhizoma Pinelliae Preparata, 32 parts of Cortex Moutan, 26 parts of Semen Celosiae, 26 parts of Indigo Naturaliss, 19 parts of Poria, 19 parts of Herba Spirodelae, 19 parts of Rhizoma Paridis, dried Alumen 19
Part, 19 parts of Scorpio, 16 parts of Pheretima, 13 parts of Radix Saposhnikoviae, 14 parts of Cornu Bubali, 13 parts of Periostracum Cicadae, 10 parts of Radix Glycyrrhizae and 10 parts of Borneolum Syntheticum.
Further, a kind of preparation method of described ointment treating herpes zoster, comprises the steps of：
（1）Fraction proportioning by weight, Herba Schizonepetae, Fructus Atriplicis Sibiricae, Fructus Forsythiae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Realgar, Radix Et Rhizoma Rhei, Rhizoma Pinelliae Preparata, Cortex Moutan are divided
Other roguing, clean after put in decoction pot, add the deionized water of 3～6 times of weight of Fructus Forsythiae, big fire will be boiled for water after turn small fire and endure
Boil 6～9h, natural filtration after cooling, collect filtrate, obtain medicinal liquid；
（2）By Semen Celosiae, Indigo Naturaliss, Poria, Herba Spirodelae, Rhizoma Paridis, dried Alumen, Scorpio, Pheretima, Radix Saposhnikoviae, Cornu Bubali, Periostracum Cicadae, Radix Glycyrrhizae respectively
Roguing, dry after, respectively grind into powder, gained powder mix homogeneously obtains mixed powder；
（3）By Radix Trichosanthis and step（2）The mixed powder mix homogeneously of gained, adds Borneolum Syntheticum and step（1）Medicinal liquid, with
The speed of 400r/min stirs, then concentrating under reduced pressure after homogenizer homogenizing, fill after microwave disinfection, obtains final product described treatment
The Chinese medicine of herpes zoster.
Further, in step（1）, the temperature of described decocting process is 98 ± 2 DEG C.
Further, in step（2）, the mesh granularity of described powder is 350～400 mesh.
Further, in step（3）, the condition of described homogenization is：Pressure is 21～25Mpa, and temperature is 75
～80 DEG C；The temperature of described microwave disinfection be 75～80 DEG C, the time be 3～4h, frequency be 2100～2500MHz, power be 6～
8kw.
Points for attention：The present invention is poisonous product, disables in oral cavity, ophthalmic conjunctiva, at cornea, this medicine allergy sufferers is prohibited
With anemia of pregnant woman uses with caution, and child should use under adult's monitoring.
In sum, the present invention, due to employing such scheme, has the positive effect that：
（1）Prescription of the present invention has medicine source widely, draws materials easily, easy to use, and drug effect is rapid, many advantages, such as save time economical,
Using cream form, it is difficult pollution clothes.
（2）The present invention has the effects such as tonifying YIN blood-nourishing, removing blood stasis eliminating stagnation, removing obstruction in the collateral to relieve pain, for treat banding herpes zoster and
Post-herpetic neuralgia.
（3）Can quickly antitoxin antiinflammatory, the impaired nervous tissue of reparation, rapid alleviation cancellation band after external application medical ointment of the present invention
Neuralgia caused by shape herpess and its sequela, can shorten the course of disease, provide to patient and facilitate quick-acting external treatment with Chinese medicine side's medicines.
Specific embodiment
Treat ointment of herpes zoster and preparation method thereof with reference to embodiment is a kind of to the present invention, make furtherly
Bright.
Embodiment 1
A kind of ointment treating herpes zoster, is made up of the raw material of Chinese medicine of following weight portion：22 parts of Herba Schizonepetae, 19 parts of Fructus Atriplicis Sibiricae, company
Stick up 19 parts, 19 parts of Radix Trichosanthis, 16 parts of Rhizoma Coptidis, 16 parts of Radix Scutellariae, 16 parts of Cortex Phellodendri, 16 parts of Realgar, 16 parts of Radix Et Rhizoma Rhei, 14 parts of Rhizoma Pinelliae Preparata, Cortex Moutan
14 parts, 11 parts of Semen Celosiae, 11 parts of Indigo Naturaliss, 8 parts of Poria, 8 parts of Herba Spirodelae, 8 parts of Rhizoma Paridis, 8 parts of dried Alumen, 8 parts of Scorpio, 7 parts of Pheretima, Radix Saposhnikoviae
7 parts, 7 parts of Cornu Bubali, 7 parts of Periostracum Cicadae, 5 parts of Radix Glycyrrhizae and 5 parts of Borneolum Syntheticum.
A kind of preparation method of ointment treating herpes zoster described above, comprises the steps of：
（1）Fraction proportioning by weight, Herba Schizonepetae, Fructus Atriplicis Sibiricae, Fructus Forsythiae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Realgar, Radix Et Rhizoma Rhei, Rhizoma Pinelliae Preparata, Cortex Moutan are divided
Other roguing, clean after put in decoction pot, decoct temperature be 98 ± 2 DEG C, add 3 times of weight of Fructus Forsythiae deionized water, big fire will
Turn small fire infusion 6h, natural filtration after cooling after water is boiled, collect filtrate, obtain medicinal liquid；
（2）By Semen Celosiae, Indigo Naturaliss, Poria, Herba Spirodelae, Rhizoma Paridis, dried Alumen, Scorpio, Pheretima, Radix Saposhnikoviae, Cornu Bubali, Periostracum Cicadae, Radix Glycyrrhizae respectively
Roguing, dry after, grind to form the powder that mesh granularity is 350 mesh respectively, gained powder mix homogeneously obtain mixed powder；
（3）By Radix Trichosanthis and step（2）The mixed powder mix homogeneously of gained, adds Borneolum Syntheticum and step（1）Medicinal liquid, with
The speed of 400r/min stirs, then concentrating under reduced pressure after homogenizer homogenizing, and the pressure of described homogenizing is 21Mpa, temperature
For 75 DEG C, fill after microwave disinfection, the temperature of described microwave disinfection is 75 DEG C, the time is 3h, frequency is 2100MHz, power is
6kw, obtains final product the Chinese medicine of described treatment herpes zoster.
Embodiment 2
A kind of ointment treating herpes zoster, is made up of the raw material of Chinese medicine of following weight portion：80 parts of Herba Schizonepetae, 70 parts of Fructus Atriplicis Sibiricae, company
Stick up 70 parts, 70 parts of Radix Trichosanthis, 55 parts of Rhizoma Coptidis, 55 parts of Radix Scutellariae, 55 parts of Cortex Phellodendri, 50 parts of Realgar, 50 parts of Radix Et Rhizoma Rhei, 50 parts of Rhizoma Pinelliae Preparata, Cortex Moutan
50 parts, 40 parts of Semen Celosiae, 40 parts of Indigo Naturaliss, 30 parts of Poria, 30 parts of Herba Spirodelae, 30 parts of Rhizoma Paridis, 30 parts of dried Alumen, 30 parts of Scorpio, Pheretima 25
Part, 20 parts of Radix Saposhnikoviae, 20 parts of Cornu Bubali, 20 parts of Periostracum Cicadae, 15 parts of Radix Glycyrrhizae and 15 parts of Borneolum Syntheticum.
A kind of preparation method of ointment treating herpes zoster described above, comprises the steps of：
（1）Fraction proportioning by weight, Herba Schizonepetae, Fructus Atriplicis Sibiricae, Fructus Forsythiae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Realgar, Radix Et Rhizoma Rhei, Rhizoma Pinelliae Preparata, Cortex Moutan are divided
Other roguing, clean after put in decoction pot, decoct temperature be 98 ± 2 DEG C, add 6 times of weight of Fructus Forsythiae deionized water, big fire will
Turn small fire infusion 9h, natural filtration after cooling after water is boiled, collect filtrate, obtain medicinal liquid；
（2）By Semen Celosiae, Indigo Naturaliss, Poria, Herba Spirodelae, Rhizoma Paridis, dried Alumen, Scorpio, Pheretima, Radix Saposhnikoviae, Cornu Bubali, Periostracum Cicadae, Radix Glycyrrhizae respectively
Roguing, dry after, grind to form the powder that mesh granularity is 400 mesh respectively, gained powder mix homogeneously obtain mixed powder；
（3）By Radix Trichosanthis and step（2）The mixed powder mix homogeneously of gained, adds Borneolum Syntheticum and step（1）Medicinal liquid, with
The speed of 400r/min stirs, then concentrating under reduced pressure after homogenizer homogenizing, and the pressure of described homogenizing is 25Mpa, temperature
For 80 DEG C, fill after microwave disinfection, the temperature of described microwave disinfection is 80 DEG C, the time is 4h, frequency is 2500MHz, power is
8kw, obtains final product the Chinese medicine of described treatment herpes zoster.
Embodiment 3
A kind of ointment treating herpes zoster, is made up of the raw material of Chinese medicine of following weight portion：37 parts of Herba Schizonepetae, 34 parts of Fructus Atriplicis Sibiricae, company
Stick up 34 parts, 34 parts of Radix Trichosanthis, 31 parts of Rhizoma Coptidis, 31 parts of Radix Scutellariae, 31 parts of Cortex Phellodendri, 31 parts of Realgar, 31 parts of Radix Et Rhizoma Rhei, 29 parts of Rhizoma Pinelliae Preparata, Cortex Moutan
29 parts, 21 parts of Semen Celosiae, 21 parts of Indigo Naturaliss, 18 parts of Poria, 18 parts of Herba Spirodelae, 18 parts of Rhizoma Paridis, 18 parts of dried Alumen, 18 parts of Scorpio, Pheretima 12
Part, 12 parts of Radix Saposhnikoviae, 12 parts of Cornu Bubali, 12 parts of Periostracum Cicadae, 8 parts of Radix Glycyrrhizae and 8 parts of Borneolum Syntheticum.
A kind of preparation method of ointment treating herpes zoster described above, comprises the steps of：
（1）Fraction proportioning by weight, Herba Schizonepetae, Fructus Atriplicis Sibiricae, Fructus Forsythiae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Realgar, Radix Et Rhizoma Rhei, Rhizoma Pinelliae Preparata, Cortex Moutan are divided
Other roguing, clean after put in decoction pot, decoct temperature be 98 ± 2 DEG C, add 4 times of weight of Fructus Forsythiae deionized water, big fire will
Turn small fire infusion 7h, natural filtration after cooling after water is boiled, collect filtrate, obtain medicinal liquid；
（2）By Semen Celosiae, Indigo Naturaliss, Poria, Herba Spirodelae, Rhizoma Paridis, dried Alumen, Scorpio, Pheretima, Radix Saposhnikoviae, Cornu Bubali, Periostracum Cicadae, Radix Glycyrrhizae respectively
Roguing, dry after, grind to form the powder that mesh granularity is 360 mesh respectively, gained powder mix homogeneously obtain mixed powder；
（3）By Radix Trichosanthis and step（2）The mixed powder mix homogeneously of gained, adds Borneolum Syntheticum and step（1）Medicinal liquid, with
The speed of 400r/min stirs, then concentrating under reduced pressure after homogenizer homogenizing, and the pressure of described homogenizing is 22Mpa, temperature
For 76 DEG C, fill after microwave disinfection, the temperature of described microwave disinfection is 76 DEG C, the time is 3.2h, frequency is 2200MHz, power
For 6.5kw, obtain final product the Chinese medicine of described treatment herpes zoster.
Embodiment 4
A kind of ointment treating herpes zoster, is made up of the raw material of Chinese medicine of following weight portion：65 parts of Herba Schizonepetae, 55 parts of Fructus Atriplicis Sibiricae, company
Stick up 55 parts, 55 parts of Radix Trichosanthis, 40 parts of Rhizoma Coptidis, 40 parts of Radix Scutellariae, 40 parts of Cortex Phellodendri, 35 parts of Realgar, 35 parts of Radix Et Rhizoma Rhei, 35 parts of Rhizoma Pinelliae Preparata, Cortex Moutan
35 parts, 30 parts of Semen Celosiae, 30 parts of Indigo Naturaliss, 20 parts of Poria, 20 parts of Herba Spirodelae, 20 parts of Rhizoma Paridis, 20 parts of dried Alumen, 20 parts of Scorpio, Pheretima 20
Part, 15 parts of Radix Saposhnikoviae, 15 parts of Cornu Bubali, 15 parts of Periostracum Cicadae, 12 parts of Radix Glycyrrhizae and 12 parts of Borneolum Syntheticum.
A kind of preparation method of ointment treating herpes zoster described above, comprises the steps of：
（1）Fraction proportioning by weight, Herba Schizonepetae, Fructus Atriplicis Sibiricae, Fructus Forsythiae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Realgar, Radix Et Rhizoma Rhei, Rhizoma Pinelliae Preparata, Cortex Moutan are divided
Other roguing, clean after put in decoction pot, decoct temperature be 98 ± 2 DEG C, add 5 times of weight of Fructus Forsythiae deionized water, big fire will
Turn small fire infusion 8h, natural filtration after cooling after water is boiled, collect filtrate, obtain medicinal liquid；
（2）By Semen Celosiae, Indigo Naturaliss, Poria, Herba Spirodelae, Rhizoma Paridis, dried Alumen, Scorpio, Pheretima, Radix Saposhnikoviae, Cornu Bubali, Periostracum Cicadae, Radix Glycyrrhizae respectively
Roguing, dry after, grind to form the powder that mesh granularity is 390 mesh respectively, gained powder mix homogeneously obtain mixed powder；
（3）By Radix Trichosanthis and step（2）The mixed powder mix homogeneously of gained, adds Borneolum Syntheticum and step（1）Medicinal liquid, with
The speed of 400r/min stirs, then concentrating under reduced pressure after homogenizer homogenizing, and the pressure of described homogenizing is 24Mpa, temperature
For 79 DEG C, fill after microwave disinfection, the temperature of described microwave disinfection is 79 DEG C, the time is 3.7h, frequency is 2400MHz, power
For 7.5kw, obtain final product the Chinese medicine of described treatment herpes zoster.
Embodiment 5
A kind of ointment treating herpes zoster, is made up of the raw material of Chinese medicine of following weight portion：51 parts of Herba Schizonepetae, 45 parts of Fructus Atriplicis Sibiricae, company
Stick up 45 parts, 45 parts of Radix Trichosanthis, 35 parts of Rhizoma Coptidis, 35 parts of Radix Scutellariae, 35 parts of Cortex Phellodendri, 33 parts of Realgar, 33 parts of Radix Et Rhizoma Rhei, 32 parts of Rhizoma Pinelliae Preparata, Cortex Moutan
32 parts, 26 parts of Semen Celosiae, 26 parts of Indigo Naturaliss, 19 parts of Poria, 19 parts of Herba Spirodelae, 19 parts of Rhizoma Paridis, 19 parts of dried Alumen, 19 parts of Scorpio, Pheretima 16
Part, 13 parts of Radix Saposhnikoviae, 14 parts of Cornu Bubali, 13 parts of Periostracum Cicadae, 10 parts of Radix Glycyrrhizae and 10 parts of Borneolum Syntheticum.
A kind of preparation method of ointment treating herpes zoster described above, comprises the steps of：
（1）Fraction proportioning by weight, Herba Schizonepetae, Fructus Atriplicis Sibiricae, Fructus Forsythiae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Realgar, Radix Et Rhizoma Rhei, Rhizoma Pinelliae Preparata, Cortex Moutan are divided
Other roguing, clean after put in decoction pot, decoct temperature be 98 ± 2 DEG C, add 4.5 times of weight of Fructus Forsythiae deionized water, big fire
Turn small fire infusion 7.5h, natural filtration after cooling after will be boiled for water, collect filtrate, obtain medicinal liquid；
（2）By Semen Celosiae, Indigo Naturaliss, Poria, Herba Spirodelae, Rhizoma Paridis, dried Alumen, Scorpio, Pheretima, Radix Saposhnikoviae, Cornu Bubali, Periostracum Cicadae, Radix Glycyrrhizae respectively
Roguing, dry after, grind to form the powder that mesh granularity is 370 mesh respectively, gained powder mix homogeneously obtain mixed powder；
（3）By Radix Trichosanthis and step（2）The mixed powder mix homogeneously of gained, adds Borneolum Syntheticum and step（1）Medicinal liquid, with
The speed of 400r/min stirs, then concentrating under reduced pressure after homogenizer homogenizing, and the pressure of described homogenizing is 23Mpa, temperature
For 77 DEG C, fill after microwave disinfection, the temperature of described microwave disinfection is 78 DEG C, the time is 3.5h, frequency is 2300MHz, power
For 7kw, obtain final product the Chinese medicine of described treatment herpes zoster.
In sum, prescription of the present invention has medicine source widely, draws materials easily, and easy to use, drug effect is rapid, save time economical etc.
Plurality of advantages, using cream form, is difficult pollution clothes.The present invention has tonifying YIN blood-nourishing, removing blood stasis eliminating stagnation, the work(such as removing obstruction in the collateral to relieve pain
Effect, for treating banding herpes zoster and post-herpetic neuralgia.After external application medical ointment of the present invention can quickly antitoxin antiinflammatory, repair
Multiple impaired nervous tissue, alleviates rapidly and eliminates the neuralgia caused by herpes zoster and its sequela, can shorten the course of disease, give
Patient provides and facilitates quick-acting external treatment with Chinese medicine side's medicines.
The foregoing is only the preferred embodiment of invention, not in order to limit the present invention, all spirit in the present invention
Within principle, any modification, equivalent substitution and improvement made etc., should be included within the scope of the present invention.
Claims (7)
1. a kind of ointment treating herpes zoster is it is characterised in that be made up of the raw material of Chinese medicine of following weight portion：Herba Schizonepetae 22～80
Part, 19～70 parts of Fructus Atriplicis Sibiricae, 19～70 parts of Fructus Forsythiae, 19～70 parts of Radix Trichosanthis, 16～55 parts of Rhizoma Coptidis, 16～55 parts of Radix Scutellariae, Cortex Phellodendri
16～55 parts, 16～50 parts of Realgar, 16～50 parts of Radix Et Rhizoma Rhei, 14～50 parts of Rhizoma Pinelliae Preparata, 14～50 parts of Cortex Moutan, 11～40 parts of Semen Celosiae,
11～40 parts of Indigo Naturaliss, 8～30 parts of Poria, 8～30 parts of Herba Spirodelae, 8～30 parts of Rhizoma Paridis, 8～30 parts of dried Alumen, 8～30 parts of Scorpio, Pheretima
7～25 parts, 7～20 parts of Radix Saposhnikoviae, 7～20 parts of Cornu Bubali, 7～20 parts of Periostracum Cicadae, 5～15 parts of Radix Glycyrrhizae and 5～15 parts of Borneolum Syntheticum.
2. a kind of ointment treating herpes zoster according to claim 1 is it is characterised in that Chinese medicine by following weight portion
Raw material is made：37～65 parts of Herba Schizonepetae, 34～55 parts of Fructus Atriplicis Sibiricae, 34～55 parts of Fructus Forsythiae, 34～55 parts of Radix Trichosanthis, Rhizoma Coptidis 31～40
Part, 31～40 parts of Radix Scutellariae, 31～40 parts of Cortex Phellodendri, 31～35 parts of Realgar, 31～35 parts of Radix Et Rhizoma Rhei, 29～35 parts of Rhizoma Pinelliae Preparata, Cortex Moutan 29～
35 parts, 21～30 parts of Semen Celosiae, 21～30 parts of Indigo Naturaliss, 18～20 parts of Poria, 18～20 parts of Herba Spirodelae, 18～20 parts of Rhizoma Paridis, dried Alumen
18～20 parts, 18～20 parts of Scorpio, 12～20 parts of Pheretima, 12～15 parts of Radix Saposhnikoviae, 12～15 parts of Cornu Bubali, 12～15 parts of Periostracum Cicadae,
8～12 parts of Radix Glycyrrhizae and 8～12 parts of Borneolum Syntheticum.
3. a kind of ointment treating herpes zoster according to claim 1 is it is characterised in that Chinese medicine by following weight portion
Raw material is made：51 parts of Herba Schizonepetae, 45 parts of Fructus Atriplicis Sibiricae, 45 parts of Fructus Forsythiae, 45 parts of Radix Trichosanthis, 35 parts of Rhizoma Coptidis, 35 parts of Radix Scutellariae, 35 parts of Cortex Phellodendri,
33 parts of Realgar, 33 parts of Radix Et Rhizoma Rhei, 32 parts of Rhizoma Pinelliae Preparata, 32 parts of Cortex Moutan, 26 parts of Semen Celosiae, 26 parts of Indigo Naturaliss, 19 parts of Poria, 19 parts of Herba Spirodelae, weight
19 parts of building, 19 parts of dried Alumen, 19 parts of Scorpio, 16 parts of Pheretima, 13 parts of Radix Saposhnikoviae, 14 parts of Cornu Bubali, 13 parts of Periostracum Cicadae, 10 parts of Radix Glycyrrhizae and Borneolum Syntheticum
10 parts.
4. the preparation method of a kind of ointment treating herpes zoster according to any one of claims 1 to 3, its feature exists
In comprising the steps of：
（1）Fraction proportioning by weight, Herba Schizonepetae, Fructus Atriplicis Sibiricae, Fructus Forsythiae, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Realgar, Radix Et Rhizoma Rhei, Rhizoma Pinelliae Preparata, Cortex Moutan are divided
Other roguing, clean after put in decoction pot, add the deionized water of 3～6 times of weight of Fructus Forsythiae, big fire will be boiled for water after turn small fire and endure
Boil 6～9h, natural filtration after cooling, collect filtrate, obtain medicinal liquid；
（2）By Semen Celosiae, Indigo Naturaliss, Poria, Herba Spirodelae, Rhizoma Paridis, dried Alumen, Scorpio, Pheretima, Radix Saposhnikoviae, Cornu Bubali, Periostracum Cicadae, Radix Glycyrrhizae respectively
Roguing, dry after, respectively grind into powder, gained powder mix homogeneously obtains mixed powder；
（3）By Radix Trichosanthis and step（2）The mixed powder mix homogeneously of gained, adds Borneolum Syntheticum and step（1）Medicinal liquid, with
The speed of 400r/min stirs, then concentrating under reduced pressure after homogenizer homogenizing, fill after microwave disinfection, obtains final product described treatment
The Chinese medicine of herpes zoster.
5. a kind of ointment treating herpes zoster according to claim 4 preparation method it is characterised in that：In step
（1）, the temperature of described decocting process is 98 ± 2 DEG C.
6. a kind of ointment treating herpes zoster according to claim 4 preparation method it is characterised in that：In step
（2）, the mesh granularity of described powder is 350～400 mesh.
7. a kind of ointment treating herpes zoster according to claim 4 preparation method it is characterised in that：In step
（3）, the condition of described homogenization is：Pressure is 21～25Mpa, and temperature is 75～80 DEG C；The temperature of described microwave disinfection is
75～80 DEG C, the time is 3～4h, and frequency is 2100～2500MHz, and power is 6～8kw.
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| CN108283650A (en) * | 2018-04-18 | 2018-07-17 | 董新声 | A kind of externally applied drug that treating bleb and application method |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102106881A (en) * | 2011-03-28 | 2011-06-29 | 李玉春 | Medicament for treating shingles and preparation method thereof |
| CN104042761A (en) * | 2014-07-05 | 2014-09-17 | 朱克兰 | Traditional Chinese medicine (TCM) composition for treating herpes zoster |
-
2016
- 2016-10-28 CN CN201610965601.5A patent/CN106421289A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102106881A (en) * | 2011-03-28 | 2011-06-29 | 李玉春 | Medicament for treating shingles and preparation method thereof |
| CN104042761A (en) * | 2014-07-05 | 2014-09-17 | 朱克兰 | Traditional Chinese medicine (TCM) composition for treating herpes zoster |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108283650A (en) * | 2018-04-18 | 2018-07-17 | 董新声 | A kind of externally applied drug that treating bleb and application method |
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