CN106390528A - Vacuum bubble-removing apparatus used in preparation of enteral nutritional emulsion - Google Patents
Vacuum bubble-removing apparatus used in preparation of enteral nutritional emulsion Download PDFInfo
- Publication number
- CN106390528A CN106390528A CN201510466833.1A CN201510466833A CN106390528A CN 106390528 A CN106390528 A CN 106390528A CN 201510466833 A CN201510466833 A CN 201510466833A CN 106390528 A CN106390528 A CN 106390528A
- Authority
- CN
- China
- Prior art keywords
- vacuum
- froth
- enteral nutritional
- preparation
- nutritional emulsion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention provides a vacuum bubble-removing apparatus to overcome the problem that a great amount of bubbles are produced during mixing of an oil phase and a water phase in preparation of an enteral nutritional emulsion due to high-speed shearing and existence o fan emulsifier. The apparatus removes bubbles of the enteral nutritional emulsion with certain viscosity by using the negative pressure of a vacuum environment.
Description
Technical field
The present invention relates to Enteral Nutrition Emulsion technical field, specifically, this is related to a kind of preparation and the defoaming device during fill Enteral Nutrition Emulsion.
Background technology
Froth in vacuum refers to that the low viscous Emulsion of centering carries out froth breaking under the vacuum environment of vacuum chamber.Vacuum environment can descend de-bubble, and the method simply by physics carries out froth breaking, does not interfere with the physicochemical property of Emulsion.In vacuum environment, Emulsion penetrates into vacuum intracavity and sees Fig. 1；There is pressure differential due to inside and outside, Emulsion can flow to vacuum intracavity, when increasing pressure, there is pressure differential, bubble breaking inside and outside bubble, see Fig. 2.Can be very good to carry out the operation of next step, such as homogenizing or subpackage through the emulsion of deaeration it is ensured that producing the Enteral Nutrition Emulsion of more high-quality.
Content of the invention
The present invention is directed in Enteral Nutrition Emulsion preparation process, during water-oil phase mixing, due to the presence of high speed shear and emulsifying agent, a kind of a large amount of bubbles of generation, there is provided defoaming device.This froth breaking suzerain carries out de-bubble using vacuum environment to the Enteral Nutrition Emulsion having certain viscosity.
Froth in vacuum device is to carry out froth breaking using the negative pressure of vacuum environment, and vacuum environment negative pressure is 0.1-250 millipascal；Its pipeline and inner chamber are high-strength stainless steel, and pipeline can be prevented to be corroded.The inside of froth in vacuum device is vacuum, and due to subnormal ambient, liquid can flow into.And one nitrogen pressure pump of configuration is not destroyed ensureing material when flowing out, prevent air oxidation.Charging aperture is connected to blending tank/storage tank, and discharging opening leads to high pressure homogenizer/canned streamline, carries out the Emulsion after de-bubble operation, more homogeneous, preserves beneficial to long-term.
Brief description：
Fig. 1. froth in vacuum chamber when not pressurizeing；Fig. 2. froth in vacuum chamber during pressurization.
Specific embodiment：
In order that the technological means of the present invention and effect are easy to understand, illustrate with reference to concrete scheme.
Case study on implementation 1：
Open nitrogen pump, the material flow of froth in vacuum device is set to 20 ml/min, and pressure is set as 200 mPa.
Case study on implementation 2
Open nitrogen pump, the material flow of froth in vacuum device is set to 15 ml/min, and pressure is set as 150 mPa.
Case study on implementation 3
Open nitrogen pump, the material flow of froth in vacuum device is set to 10 ml/min, and pressure is set as 100 mPa.
Tested according to above-mentioned case study on implementation, checked its defoaming effect, found that the defoaming effect of three kinds of schemes all reaches production requirement.
Claims (6)
1. a kind of froth in vacuum device of preparing during Enteral Nutrition Emulsion is the subnormal ambient froth breaking using vacuum environment.
2. as claimed in claim 1, vacuum environment negative pressure is 0.1 millipascal -250 millipascal.
3. as claimed in claim 1, froth in vacuum installs pipes and inner chamber is high-strength stainless steel, and pipeline can be prevented to be corroded.
4. as claimed in claim 1, the inside of froth in vacuum device is vacuum, because subnormal ambient liquid can automatically flow into, need to configure a compression pump during outflow.
5. compression pump as claimed in claim 4 be vacuum nitrogen pump it is ensured that material is not destroyed, prevent air oxidation.
6. froth in vacuum device as claimed in claim 3, its charging aperture is connected to blending tank/holding vessel, and discharging opening leads to high pressure homogenizer/streamline.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510466833.1A CN106390528A (en) | 2015-08-03 | 2015-08-03 | Vacuum bubble-removing apparatus used in preparation of enteral nutritional emulsion |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510466833.1A CN106390528A (en) | 2015-08-03 | 2015-08-03 | Vacuum bubble-removing apparatus used in preparation of enteral nutritional emulsion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106390528A true CN106390528A (en) | 2017-02-15 |
Family
ID=58008213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510466833.1A Pending CN106390528A (en) | 2015-08-03 | 2015-08-03 | Vacuum bubble-removing apparatus used in preparation of enteral nutritional emulsion |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106390528A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114209650A (en) * | 2021-12-24 | 2022-03-22 | 海南鑫开源医药科技有限公司 | Process for improving content uniformity of ibuprofen suspension |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010120906A (en) * | 2008-11-21 | 2010-06-03 | Ajinomoto Co Inc | Liquid state emulsified nutritive composition |
| CN102083329A (en) * | 2008-03-12 | 2011-06-01 | 荷兰纽迪希亚公司 | High protein liquid enteral nutritional composition |
| CN102342913A (en) * | 2011-09-06 | 2012-02-08 | 华瑞制药有限公司 | Intra-intestinal nutrient emulsion for tumor patients and preparation method thereof |
| CN203400531U (en) * | 2013-07-30 | 2014-01-22 | 广东厨邦食品有限公司 | De-foaming device for vacuum drum filter |
| CN203777722U (en) * | 2014-03-24 | 2014-08-20 | 四川兴能新材料有限公司 | Defoaming equipment for eliminating foam of slurry |
| CN104324062A (en) * | 2014-11-26 | 2015-02-04 | 任贵兴 | American ginseng conversion saponin, traditional Chinese medicine mouth care composition thereof and preparation method and application |
-
2015
- 2015-08-03 CN CN201510466833.1A patent/CN106390528A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102083329A (en) * | 2008-03-12 | 2011-06-01 | 荷兰纽迪希亚公司 | High protein liquid enteral nutritional composition |
| JP2010120906A (en) * | 2008-11-21 | 2010-06-03 | Ajinomoto Co Inc | Liquid state emulsified nutritive composition |
| CN102342913A (en) * | 2011-09-06 | 2012-02-08 | 华瑞制药有限公司 | Intra-intestinal nutrient emulsion for tumor patients and preparation method thereof |
| CN203400531U (en) * | 2013-07-30 | 2014-01-22 | 广东厨邦食品有限公司 | De-foaming device for vacuum drum filter |
| CN203777722U (en) * | 2014-03-24 | 2014-08-20 | 四川兴能新材料有限公司 | Defoaming equipment for eliminating foam of slurry |
| CN104324062A (en) * | 2014-11-26 | 2015-02-04 | 任贵兴 | American ginseng conversion saponin, traditional Chinese medicine mouth care composition thereof and preparation method and application |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114209650A (en) * | 2021-12-24 | 2022-03-22 | 海南鑫开源医药科技有限公司 | Process for improving content uniformity of ibuprofen suspension |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2961522B1 (en) | A method for mixing a liquid food product | |
| WO2013141695A8 (en) | Apparatus and method for mass producing a monodisperse microbubble agent | |
| AR090408A1 (en) | A MULTI MACHINE SYSTEM TO PREPARE DRINKS | |
| EP3352891B1 (en) | Mixing ring for dissolving a portion of solute in a portion of solvent | |
| RU2016126428A (en) | DRINKING MACHINE AND METHOD FOR MIXING ONE OR SEVERAL BEVERAGE COMPONENTS WITH AT LEAST ONE ONE CARBONATED LIQUID | |
| KR20150003473U (en) | Generation apparatus for dissolving gas in liquid and fluid nozzle | |
| CL2018001518A1 (en) | A beverage source for a beverage dispensing system, a beverage dispensing system comprising a beverage source and a method for dispensing a mixed alcoholic beverage product by providing a beverage dispensing system. | |
| EP3461387A3 (en) | Liquid extraction apparatus and method | |
| MX2018001007A (en) | Solid product dispenser for small volume applications. | |
| CN106390528A (en) | Vacuum bubble-removing apparatus used in preparation of enteral nutritional emulsion | |
| CN102921199B (en) | Solid antifoaming agent and preparation process thereof | |
| MX2018012807A (en) | Device and method for foaming a viscous material. | |
| MX2017011742A (en) | Device and method for degassing liquids. | |
| CN203904239U (en) | Conveying device for material mixing in emulsion explosive production | |
| CN208065838U (en) | A kind of mist eliminating device and the material-compound tank with mist eliminating function | |
| JP2018008185A (en) | Fine object dissolution device and dissolution method | |
| CN102249361B (en) | Ozone gas supply pressure stabilizing device and air flotation reactor using same | |
| CN205109108U (en) | Fire fighting equipment of emulsion preparation in -process | |
| JP6512656B2 (en) | Liquid transfer method and liquid transfer apparatus | |
| CN102921197A (en) | Vacuum spraying defoaming device | |
| JP2010028022A (en) | Additive dissolving device | |
| CN204193542U (en) | A kind of balance Differential Pressure Unit of dimeric dibasic acid molecular clock | |
| CN106693448A (en) | Defoaming method used for preparation process of emulsifier | |
| CN206587775U (en) | A kind of quality testing separatory funnel | |
| JP2009138849A (en) | Low pressure transportation method and low pressure transportation system for processing solution |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170215 |
|
| RJ01 | Rejection of invention patent application after publication |