CN106390521B - The assembly device of chromatographic column stationary phase - Google Patents

The assembly device of chromatographic column stationary phase Download PDF

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Publication number
CN106390521B
CN106390521B CN201611039602.3A CN201611039602A CN106390521B CN 106390521 B CN106390521 B CN 106390521B CN 201611039602 A CN201611039602 A CN 201611039602A CN 106390521 B CN106390521 B CN 106390521B
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China
Prior art keywords
column
assembly
assemble mechanism
chromatographic column
stationary phase
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Application number
CN201611039602.3A
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Chinese (zh)
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CN106390521A (en
Inventor
瞿欢欢
朱至放
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Suzhou Bo Bo Biotechnology Co Ltd
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Suzhou Bo Bo Biotechnology Co Ltd
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Priority to CN201611039602.3A priority Critical patent/CN106390521B/en
Publication of CN106390521A publication Critical patent/CN106390521A/en
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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/22Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the construction of the column

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

The invention discloses a kind of assembly devices of chromatographic column stationary phase, comprising: rack comprising pedestal and the support column being vertically installed on the pedestal;It is set to the assemble mechanism of the support column side;And it is set to the support platform immediately below the assemble mechanism, wherein the support platform is equipped with the carrier for loading chromatographic column cylinder to be assembled, and the assemble mechanism can slide up and down along the support column.According to the present invention, with high degree of automation, assembly efficiency is improved while reducing cost of labor, additionally it is possible to substantially reduce chromatographic column stationary phase by the beneficial effect of the probability of secondary pollution.

Description

The assembly device of chromatographic column stationary phase
Technical field
The present invention relates to a kind of assembly device, in particular to a kind of assembly device of chromatographic column stationary phase.
Background technique
Chromatographic column can be used in industrial manufacture process to carry out purification to process liquid and isolate from process liquid Interested substance.Impurity is inevitably mixed into when preparing the chemical products such as protein and drug, and in actually using It is very high to the purity requirement of protein and drug this substance, therefore, it is general using chromatographic column come to protein and drug etc. into Row purifying, to obtain the product of high-purity.
In chromatographic column assembling process, the assembly of stationary phase is a mostly important ring, in the prior art, assembly Process automation degree is low, causes assembly efficiency low;Human assistance step is more, causes chromatographic column stationary phase to be subject to secondary Pollution.In view of this, it is really necessary to develop a kind of assembly device of chromatographic column stationary phase, to solve the above problems.
Summary of the invention
Shortcoming present in view of the above technology, the object of the present invention is to provide a kind of assembly of chromatographic column stationary phase Device, high degree of automation improve assembly efficiency while reducing cost of labor, additionally it is possible to substantially reduce chromatographic column stationary phase By the probability of secondary pollution.
In order to realize above-mentioned purpose according to the present invention and other advantages, a kind of assembly dress of chromatographic column stationary phase is provided It sets, comprising:
Rack comprising pedestal and the support column being vertically installed on the pedestal;
It is set to the assemble mechanism of the support column side;And
The support platform being set to immediately below the assemble mechanism,
Wherein, the support platform is equipped with the carrier for loading chromatographic column cylinder to be assembled, and the assemble mechanism can It is slid up and down along the support column.
Preferably, side opposite with the assemble mechanism on the support column is equipped with upper rail and lower guideway, described Upper rail is parallel to each other and horizontally extending with lower guideway.
Preferably, be connected with mobile column on the upper rail and lower guideway, the mobile column can in the upper rail and Selectively toward polyslip on lower guideway, the assemble mechanism is connect by the mobile column with the support column.
Preferably, the sliding rail frame of L-shaped is connected in the mobile column, the sliding rail frame includes orthogonal level Arm and vertical arm, the vertical arm are vertically arranged and can the selectively slidings up and down in the mobile column.
Preferably, the assemble mechanism is slidably connected with the horizontal arm.
Preferably, the assemble mechanism includes:
The assembly supporter being slidably connected with the horizontal arm;
Assembly suction nozzle set on the assembly supporter bottom end;And
The vacuum cylinder of pull of vacuum is generated for the assembly suction nozzle,
Wherein, the vacuum cylinder is set on the assembly supporter, and the lower end of the assembly suction nozzle offers permission layer The sucker that column stationary phase enters is analysed, the push rod for releasing chromatographic column stationary phase is equipped with inside the top of the assembly suction nozzle.
Preferably, the assembly suction nozzle is oppositely arranged with the carrier, and the carrier offers to be assembled for accommodating The holding tank of chromatographic column cylinder.
Compared with prior art, the present invention the beneficial effect is that: high degree of automation improves while reducing cost of labor Assembly efficiency, additionally it is possible to substantially reduce chromatographic column stationary phase by the probability of secondary pollution.
Detailed description of the invention
Fig. 1 is the three-dimensional structure diagram according to the assembly device of chromatographic column stationary phase in an embodiment of the present invention.
Specific embodiment
Present invention will be described in further detail below with reference to the accompanying drawings, foregoing end other objects of the invention, feature, side Face and advantage will be apparent, and so that those skilled in the art can carry out according to the description.
Referring to Fig. 1, the assembly device 100 of chromatographic column stationary phase include: rack 110, power supply box 120, mobile column 130 and Assemble mechanism 140, wherein rack 110 includes pedestal 111 and the support column 112 being vertically installed on pedestal 111;Assembly machine Structure 140 is set to the side of support column 112, and support platform 116 is provided with immediately below assemble mechanism, is set in support platform 116 There is the carrier 117 for loading chromatographic column cylinder to be assembled, assemble mechanism 140 can slide along about 112 support column.Implement one In mode, the root of support column 112 is equipped with ribs 113, and power supply box 120 is set on pedestal 111 and is located at assemble mechanism 140 Opposite side.
Referring again to Fig. 1, the side opposite with assemble mechanism 140 is equipped with upper rail 115 and lower guideway on support column 112 114, upper rail 115 is parallel to each other and horizontally extending with lower guideway 114, is clamped on upper rail 115 and lower guideway 114 There is mobile column 130, mobile column 130 can be on upper rail 115 and lower guideway 114 selectively toward polyslip, and assemble mechanism 140 is logical It crosses mobile column 130 to connect with support column 112, the sliding rail frame 141 of L-shaped is connected in mobile column 130, sliding rail frame 141 includes phase Mutually vertical horizontal arm 141a and vertical arm 141b, vertical arm 141b be vertically arranged and can in mobile column 112 selectively on Lower sliding, and assemble mechanism 140 is slidably connected with horizontal arm 141a.
Specifically, assemble mechanism 140 includes:
The assembly supporter 142 being slidably connected with horizontal arm 141a;
Assembly suction nozzle 143 set on assembly 142 bottom end of supporter;And
The vacuum cylinder 144 of pull of vacuum is generated for assembling suction nozzle 143,
Wherein, vacuum cylinder 144 is set on assembly supporter 142, and the lower end of assembly suction nozzle 143 offers permission chromatographic column The sucker 143a that stationary phase enters assembles the push rod being equipped with inside the top of suction nozzle 143 for releasing chromatographic column stationary phase 143b。
Referring to Fig.1, assembly suction nozzle 143 is oppositely arranged with carrier 117, and carrier 117 is offered for accommodating chromatography to be assembled The holding tank of column cylinder.
Number of devices and treatment scale described herein are for simplifying explanation of the invention.To application of the invention, Modifications and variations will be readily apparent to persons skilled in the art.
Although the embodiments of the present invention have been disclosed as above, but it is not limited in listed fortune in specification and embodiments With it can be fully applied to various fields suitable for the present invention, for those skilled in the art, can be easily real Now other modification, therefore without departing from the general concept defined in the claims and the equivalent scope, the present invention is not limited to Specific details and legend shown and described herein.

Claims (2)

1. a kind of assembly device of chromatographic column stationary phase characterized by comprising
Rack comprising pedestal and the support column being vertically installed on the pedestal;
It is set to the assemble mechanism of the support column side;And
The support platform being set to immediately below the assemble mechanism,
Wherein, the support platform is equipped with the carrier for loading chromatographic column cylinder to be assembled, and the assemble mechanism can be along institute It states support column to slide up and down, the side opposite with the assemble mechanism is equipped with upper rail and lower guideway on the support column, described Upper rail is parallel to each other and horizontally extending with lower guideway, and mobile column, institute are connected on the upper rail and lower guideway State mobile column can on the upper rail and lower guideway selectively toward polyslip, the assemble mechanism by the mobile column with The support column connects, and the sliding rail frame of L-shaped is connected in the mobile column, the sliding rail frame includes orthogonal horizontal arm And vertical arm, the vertical arm be vertically arranged and can in the mobile column selectively up and down sliding, the assemble mechanism with The horizontal arm is slidably connected, and the assemble mechanism includes:
The assembly supporter being slidably connected with the horizontal arm;
Assembly suction nozzle set on the assembly supporter bottom end;And
The vacuum cylinder of pull of vacuum is generated for the assembly suction nozzle,
Wherein, the vacuum cylinder is set on the assembly supporter, and the lower end of the assembly suction nozzle offers permission chromatographic column The top inside of the sucker that stationary phase enters, the assembly suction nozzle is equipped with the push rod for releasing chromatographic column stationary phase.
2. the assembly device of chromatographic column stationary phase as described in claim 1, which is characterized in that the assembly suction nozzle and the load Tool is oppositely arranged, and the carrier offers the holding tank for accommodating chromatographic column cylinder to be assembled.
CN201611039602.3A 2016-11-11 2016-11-11 The assembly device of chromatographic column stationary phase Active CN106390521B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201611039602.3A CN106390521B (en) 2016-11-11 2016-11-11 The assembly device of chromatographic column stationary phase

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201611039602.3A CN106390521B (en) 2016-11-11 2016-11-11 The assembly device of chromatographic column stationary phase

Publications (2)

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CN106390521A CN106390521A (en) 2017-02-15
CN106390521B true CN106390521B (en) 2019-02-19

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111238563B (en) * 2020-04-23 2021-12-24 南京泰普森自动化设备有限公司 Measuring device driven by a single drive

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN202877846U (en) * 2012-10-17 2013-04-17 泉州安科卫浴有限公司 Torque force assembling device of bibcock valve core pressing cover
CN105583607A (en) * 2016-02-25 2016-05-18 浙江大学宁波理工学院 Assembling device and assembling method for shaft parts and hole parts
CN206198765U (en) * 2016-11-11 2017-05-31 苏州楚博生物技术有限公司 The assembling device of chromatographic column fixing phase

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI586463B (en) * 2015-01-06 2017-06-11 Chen Peng-Ren CNC double spindle drive

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN202877846U (en) * 2012-10-17 2013-04-17 泉州安科卫浴有限公司 Torque force assembling device of bibcock valve core pressing cover
CN105583607A (en) * 2016-02-25 2016-05-18 浙江大学宁波理工学院 Assembling device and assembling method for shaft parts and hole parts
CN206198765U (en) * 2016-11-11 2017-05-31 苏州楚博生物技术有限公司 The assembling device of chromatographic column fixing phase

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