CN106370760A - Coupling interface used for gas chromatographic column and high-field asymmetric waveform ion mobility spectrometry - Google Patents
Coupling interface used for gas chromatographic column and high-field asymmetric waveform ion mobility spectrometry Download PDFInfo
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- CN106370760A CN106370760A CN201510442516.6A CN201510442516A CN106370760A CN 106370760 A CN106370760 A CN 106370760A CN 201510442516 A CN201510442516 A CN 201510442516A CN 106370760 A CN106370760 A CN 106370760A
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- chromatographic column
- gas chromatographic
- rustless steel
- stainless steel
- ion mobility
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Abstract
The invention provides a coupling interface used for a gas chromatographic column and high-field asymmetric waveform ion mobility spectrometry. The coupling interface is formed by a stainless steel pressure cap, a high temperature-resistant sealing gasket, a stainless steel internal and external screwed joint and a high temperature-resistant stainless steel rapid joint, the stainless steel pressure cap is screwed with the external thread of the stainless steel internal and external screwed joint, the high temperature-resistant sealing gasket is arranged between the stainless steel pressure cap and the stainless steel internal and external screwed joint, the internal thread of the stainless steel internal and external screwed joint is screwed with the external thread of the high temperature-resistant stainless steel rapid joint, and the other end of the high temperature-resistant stainless steel rapid joint is connected with the sample feeding tube of a high-field asymmetric waveform ion mobility spectrometric gas passage. The coupling interface can be conveniently and rapidly assembled and dismounted, has good high temperature resistance, good pressure resistance and good sealing property, and guarantees the detection reliability.
Description
Technical field
Present invention relates particularly to a kind of combination for gas chromatographic column and High-Field asymmetric waveform ion mobility spectrometry
Interface.
Background technology
Gas chromatogram (gas chromatography abbreviation gc) is occurring nineteen fifties
Great science and technology achievement.This is a kind of new separation, analytical technology, it industry, agricultural, national defence,
It is obtained for extensive application in construction, scientific research.Gas chromatogram can be divided into gas-solid chromatograph and gas-liquid chromatograph.
Gas chromatography refers to the chromatography with gas as mobile phase.Due to sample, transmission speed is fast in the gas phase,
Therefore sample component can instantaneously reach balance between mobile phase and fixing phase.In addition add and be selected as admittedly
The material determining phase is a lot, and therefore gas chromatography is the separation analysis that an analyze speed is fast and separation efficiency is high
Method.
High-Field asymmetric waveform ion mobility spectrometry (faims) is in just difference off field using ionic mobility
Carry out ion isolation.Sample enters ionized region by carrier gas band, and the sample ions being then ionized enter migration
Area.Migration area is generally two pieces of parallel flat boards.Penetrating of asymmetric waveform is added on one flat plate wherein
Frequency electric field, another piece of ground connection.In migration area, ion can hung down with carrier gas direction in the presence of high-frequency electric field
The motion shaken up and down is done on straight direction.Because the mobility in height field ion is different, in high-frequency electric field
Each cycle, ion all can produce a displacement in vertical direction, and final ion is got to and fallen into oblivion on pole plate
Knock out.If the offset voltage of a coupling is applied on high-frequency electric field, offset ion and produce y under asymmetric field
The displacement in direction, enables ion to pass through drift region, reaches detection pole.By within the specific limits to compensation
Voltage is scanned it is possible to make different sample ions reach inspection by migration area under specific offset voltage
Survey pole, realize the detection of sample, reach the purpose of selective enumeration method sample by applying specific offset voltage.
Have using the instrument that High-Field asymmetric waveform Ion mobility spectrometry shapes that highly sensitive, speed is fast, small volume
The advantages of.
Separation efficiency using gas chromatogram is high, the high detection sensitivity of High-Field asymmetric waveform ion mobility spectrometry
Feature, both is combined and has the advantages that sensitivity for analysis is high, selectivity is strong, range of application is wider.With
And come be how to select gas chromatographic column easily, suitable and High-Field asymmetric waveform ion mobility spectrometry
Instrument connecting interface becomes focus associated with both technology.
The present invention provide a kind of gas chromatographic column and High-Field asymmetric waveform ion mobility spectrometry connecting interface it is simply that
In order to solve gas chromatographic column and interface problem associated with High-Field asymmetric waveform ion mobility spectrometry, using by
All nipple, high temperature resistant stainless steel fast joint four inside and outside rustless steel pressure cap, refractory seals pad, rustless steel
Part constitute connector, solve well associated with problem, this interface is very convenient, high temperature resistant, gas
Close property is preferably it is ensured that the reliability of its detection.
Content of the invention
It is an object of the invention to provide the combination of a kind of gas chromatographic column and High-Field asymmetric waveform ion mobility spectrometry
Interface, connecting interface is by rustless steel pressure cap, refractory seals pad, rustless steel internal and external threads joint, high temperature resistant
Rustless steel snap joint four part is constituted, the external thread spiro fastening of rustless steel pressure cap and rustless steel internal and external threads joint,
It is provided with refractory seals pad between the connecting end surface of rustless steel pressure cap and rustless steel internal and external threads joint, stainless
The female thread of steel internal and external threads joint and the external thread spiro fastening of high temperature resistant stainless steel snap joint, high temperature resistant stainless
The other end of steel snap joint is connected with the sample feeding pipe of High-Field asymmetric waveform ion mobility spectrometry gas circuit.
By gas chromatographic column pass through refractory seals pad introduce connecting interface inside, and gas chromatographic column with resistance to
Elevated-temperature seal pad contact position No leakage, sample to be separated enters gas chromatographic column through mobile phase carrier, flows through
Rustless steel pressure cap and refractory seals pad are passed through inside rustless steel internal and external threads joint, then through gas chromatographic column
The port of export enter High-Field asymmetric waveform ion mobility spectrometry be analyzed, connecting interface as gas chromatographic column with
The communication means of sample feeding pipe are sealing state.
The present invention provides a kind of operating procedure that gas chromatographic column introduces connecting interface, but is not restricted to this
The method of kind, specially before connecting interface assembling, with syringe needle by the port of gas chromatographic column from stainless
Steel pressure cap and refractory seals pad pass through, and after connecting interface assembling, so that gas chromatographic column is introduced up through not
The inside of rust steel internal and external threads joint is it is ensured that gas chromatographic column and High-Field asymmetric waveform ion mobility spectrometry gas circuit
Sample feeding pipe connection.
Described rustless steel internal and external threads joint is two pass joints that the external screw thread other end is female thread for one end.
Described refractory seals pad is resistant to elevated temperatures elastic material, for rustless steel pressure cap capillary inlet part
And the sealing of rustless steel pressure cap and rustless steel internal and external threads joint contact surfaces, the thickness root of refractory seals pad
Specification according to rustless steel pressure cap is configured, described high temperature resistant refer to that material tolerable temperature is not less than 100 DEG C, institute
The thickness stating refractory seals pad is usually 1mm～5mm.
Refractory seals pad is made up of the mid portion of circular protrusions and circular base, middle rounded projections
Divide with the in the same size of rustless steel pressure cap capillary inlet part and seal against each other and be connected, refractory seals pad is justified
Shape base diameter is equal to the externally threaded round thread face diameter of rustless steel internal and external threads joint it is preferred that institute
Stating refractory seals pad is silica gel, polyfluoroprene or fourth cyanogen glue.
The high temperature resistant stainless steel snap joint port of export internal diameter of connecting interface is equal with sample feeding pipe external diameter, sample feeding pipe
Ensure junction tight, described high temperature resistant stainless steel snap joint in insertion high temperature resistant stainless steel snap joint
Including sealing ring it is ensured that access sample feeding pipe when connecting interface gas-tight, sample feeding pipe and high temperature resistant stainless steel
When snap joint connects, push sample feeding pipe and pass through sealing ring.
Gas chromatographic column is passed through and can extract syringe needle after refractory seals pad by described syringe needle, described gas
Phase chromatographic column is capillary column or packed column.
The invention provides a kind of be exclusively used in the connection that gas chromatographic column connects High-Field asymmetric waveform ion mobility spectrometry
With interface, this connecting interface is satisfied with to air-tightness, pressure, resistant to elevated temperatures requirement, simultaneously in assembly company
Connect the requirement also meeting quick assembly and disassembly.
Advantages of the present invention and having the beneficial effect that
In detection sample, the separation efficiency using gas chromatogram is high, High-Field asymmetric waveform ion mobility spectrometry
The feature of high detection sensitivity, by both combine with sensitivity for analysis high, selectivity is strong, range of application
Wider the advantages of, the thing followed is how to select gas chromatographic column easily, suitable and High-Field asymmetric
Waveform ion mobility spectrometer connecting interface becomes focus associated with both technology.The combination that the present invention provides connects
Mouthful can assembly and disassembly conveniently and quickly, in high temperature resistant, pressure, sealing functional it is ensured that
The reliability of its detection.
Brief description
Fig. 1 is that gas chromatographic column is illustrated with High-Field asymmetric waveform ion mobility spectrometry connecting interface coupling assembly
Figure；
Fig. 2 is shown with High-Field asymmetric waveform ion mobility spectrometry connecting interface coupling assembly section for gas chromatographic column
It is intended to；
Fig. 3 is shown with High-Field asymmetric waveform ion mobility spectrometry connecting interface coupling assembly left view for gas chromatographic column
It is intended to；
In Fig. 1-3,1 is gas chromatographic column；2 is rustless steel pressure cap；3 is rustless steel internal and external threads joint；4
For high temperature resistant stainless steel fast joint；5 is sample feeding pipe；6 is refractory seals pad.
Specific embodiment
Following examples illustrate but do not limit invention which is intended to be protected.
Embodiment 1
A kind of gas chromatographic column and the connecting interface of High-Field asymmetric waveform ion mobility spectrometry, by rustless steel pressure cap
2nd, refractory seals pad 6, rustless steel internal and external threads joint 3, high temperature resistant stainless steel snap joint 4 four part
Screw togather and form, gas chromatographic column is fixed on coupling assembly by refractory seals pad 6 by rustless steel pressure cap 2
One end, the external screw thread of rustless steel internal and external threads joint 3 and rustless steel pressure cap 2 are screwed；Spiral shell inside and outside rustless steel
The female thread of stricture of vagina joint 3 is screwed with the external screw thread of high temperature resistant stainless steel snap joint 4, through this interface by gas
Phase chromatographic column is connected with the injection port of High-Field asymmetric waveform ion mobility spectrometry, whole sealing adaptor mouth is pressure,
Sealing is preferable.
Sample to be separated enters gas chromatographic column 1 through mobile phase carrier, flows through rustless steel pressure cap 2 and high temperature resistant
Sealing gasket 6 is passed through in rustless steel internal and external threads joint 3, then enters High-Field through gas chromatographic column 1 outlet port
Asymmetric waveform ion mobility spectrometry is analyzed.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, although reference
Previous embodiment has been described in detail to the present invention, and for a person skilled in the art, it is still
Technical scheme described in foregoing embodiments can be modified, or wherein some technical characteristics are entered
Row equivalent, all any modifications within the spirit and principles in the present invention, made, equivalent, changes
Enter, should be included within the scope of the present invention.
Claims (7)
1. a kind of connecting interface for gas chromatographic column and High-Field asymmetric waveform ion mobility spectrometry, its feature
It is: connecting interface is by rustless steel pressure cap (2), refractory seals pad (6), rustless steel internal and external threads joint
(3), high temperature resistant stainless steel snap joint (4) four part is constituted, in rustless steel pressure cap (2) and rustless steel
The external thread spiro fastening of male connection (3), rustless steel pressure cap (2) and rustless steel internal and external threads joint (3)
Connecting end surface between be provided with refractory seals pad (6), the female thread of rustless steel internal and external threads joint (3)
With the external thread spiro fastening of high temperature resistant stainless steel snap joint (4), high temperature resistant stainless steel snap joint (4)
The other end is connected with the sample feeding pipe (5) of High-Field asymmetric waveform ion mobility spectrometry gas circuit, and connecting interface is by gas
Phase chromatographic column (1) is in sealing state after connecting with sample feeding pipe (5).
2. connect according to the combination of gas chromatographic column described in claim 1 and High-Field asymmetric waveform ion mobility spectrometry
Mouthful it is characterised in that: by gas chromatographic column (1) pass through refractory seals pad (6) introduce connecting interface in
Portion, and gas chromatographic column (1) and refractory seals pad (6) contact position No leakage, sample to be separated
Enter gas chromatographic column (1) through mobile phase carrier, flow through rustless steel pressure cap (2) and refractory seals pad (6)
It is passed through rustless steel internal and external threads joint (3) inside, then the port of export through gas chromatographic column (1) enters High-Field
Asymmetric waveform ion mobility spectrometry is analyzed.
3. connect according to the combination of gas chromatographic column described in claim 2 and High-Field asymmetric waveform ion mobility spectrometry
Mouthful it is characterised in that: before connecting interface assembling, with syringe needle by the port of gas chromatographic column (1)
Pass through from rustless steel pressure cap (2) and refractory seals pad (6), after connecting interface assembling, make gas chromatogram
Post (1) introduce inside up through rustless steel internal and external threads joint (3) it is ensured that gas chromatographic column with high
Sample feeding pipe (5) connection of field asymmetric waveform ion mobility spectrometry gas circuit.
4. connect according to the combination of gas chromatographic column described in claim 1 and High-Field asymmetric waveform ion mobility spectrometry
Mouthful it is characterised in that: described refractory seals pad (6) be resistant to elevated temperatures elastic material, for rustless steel pressure
Cap (2) capillary inlet part and rustless steel pressure cap (2) contact with rustless steel internal and external threads joint (3)
Sealing between end face, the thickness of refractory seals pad (6) is set according to the specification of rustless steel pressure cap (2)
Put, described high temperature resistant refer to that material tolerable temperature is not less than 100 DEG C.
5. connect according to the combination of gas chromatographic column described in claim 4 and High-Field asymmetric waveform ion mobility spectrometry
Mouthful it is characterised in that: refractory seals pad (6) is made up of the mid portion of circular protrusions and circular base,
Middle circular protruding portion with the in the same size of rustless steel pressure cap (2) capillary inlet part and seals against each other
Connect, rustless steel internal and external threads joint (3) end face that refractory seals pad (6) cup dolly is in contact with it
Equal diameters, described refractory seals pad (6) is silica gel, polyfluoroprene or fourth cyanogen glue.
6. connect according to the combination of gas chromatographic column described in claim 1 and High-Field asymmetric waveform ion mobility spectrometry
Mouthful it is characterised in that: high temperature resistant stainless steel snap joint (4) port of export internal diameter of connecting interface and sample feeding pipe
(5) external diameter is equal, ensures junction no in sample feeding pipe (5) insertion high temperature resistant stainless steel snap joint (4)
Space, described high temperature resistant stainless steel snap joint (4) includes sealing ring it is ensured that when accessing sample feeding pipe (5)
Connecting interface gas-tight, when sample feeding pipe (5) is connected with high temperature resistant stainless steel snap joint (4), pushes away
Sample feeding pipe (5) is sent to pass through sealing ring.
7. connect according to the combination of gas chromatographic column described in claim 3 and High-Field asymmetric waveform ion mobility spectrometry
Mouthful it is characterised in that: described syringe needle by gas chromatographic column (1) pass through refractory seals pad after
Extract syringe needle, described gas chromatographic column is capillary column or packed column.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510442516.6A CN106370760A (en) | 2015-07-24 | 2015-07-24 | Coupling interface used for gas chromatographic column and high-field asymmetric waveform ion mobility spectrometry |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510442516.6A CN106370760A (en) | 2015-07-24 | 2015-07-24 | Coupling interface used for gas chromatographic column and high-field asymmetric waveform ion mobility spectrometry |
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| Publication Number | Publication Date |
|---|---|
| CN106370760A true CN106370760A (en) | 2017-02-01 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510442516.6A Pending CN106370760A (en) | 2015-07-24 | 2015-07-24 | Coupling interface used for gas chromatographic column and high-field asymmetric waveform ion mobility spectrometry |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111604675A (en) * | 2019-02-26 | 2020-09-01 | 株式会社岛津制作所 | Device for replacing adsorption tube |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4888112A (en) * | 1986-11-06 | 1989-12-19 | Labomatic Gmbh | Chromatographic column |
| JPH10170490A (en) * | 1996-12-11 | 1998-06-26 | Tosoh Corp | Different-diameter connecting joint and analyzing device using the same |
| CN201886005U (en) * | 2010-12-16 | 2011-06-29 | 大连中汇达科学仪器有限公司 | Gas-path adapter |
| CN103165385A (en) * | 2011-12-19 | 2013-06-19 | 中国科学院大连化学物理研究所 | Ion migration spectrum micro current signal take-away device |
| CN104020237A (en) * | 2014-06-24 | 2014-09-03 | 武汉矽感科技有限公司 | Improved FastGC column device capable of combination with ion mobility spectrometer |
-
2015
- 2015-07-24 CN CN201510442516.6A patent/CN106370760A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4888112A (en) * | 1986-11-06 | 1989-12-19 | Labomatic Gmbh | Chromatographic column |
| JPH10170490A (en) * | 1996-12-11 | 1998-06-26 | Tosoh Corp | Different-diameter connecting joint and analyzing device using the same |
| CN201886005U (en) * | 2010-12-16 | 2011-06-29 | 大连中汇达科学仪器有限公司 | Gas-path adapter |
| CN103165385A (en) * | 2011-12-19 | 2013-06-19 | 中国科学院大连化学物理研究所 | Ion migration spectrum micro current signal take-away device |
| CN104020237A (en) * | 2014-06-24 | 2014-09-03 | 武汉矽感科技有限公司 | Improved FastGC column device capable of combination with ion mobility spectrometer |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111604675A (en) * | 2019-02-26 | 2020-09-01 | 株式会社岛津制作所 | Device for replacing adsorption tube |
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Application publication date: 20170201 |