CN106353390B - The method that Electron Beam Irradiation prepares graphite oxide alkenyl enzyme-free glucose sensor - Google Patents
The method that Electron Beam Irradiation prepares graphite oxide alkenyl enzyme-free glucose sensor Download PDFInfo
- Publication number
- CN106353390B CN106353390B CN201610847831.1A CN201610847831A CN106353390B CN 106353390 B CN106353390 B CN 106353390B CN 201610847831 A CN201610847831 A CN 201610847831A CN 106353390 B CN106353390 B CN 106353390B
- Authority
- CN
- China
- Prior art keywords
- enzyme
- glucose sensor
- electron beam
- graphene oxide
- free glucose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/48—Systems using polarography, i.e. measuring changes in current under a slowly-varying voltage
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J31/00—Catalysts comprising hydrides, coordination complexes or organic compounds
- B01J31/26—Catalysts comprising hydrides, coordination complexes or organic compounds containing in addition, inorganic metal compounds not provided for in groups B01J31/02 - B01J31/24
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J37/00—Processes, in general, for preparing catalysts; Processes, in general, for activation of catalysts
- B01J37/34—Irradiation by, or application of, electric, magnetic or wave energy, e.g. ultrasonic waves ; Ionic sputtering; Flame or plasma spraying; Particle radiation
- B01J37/341—Irradiation by, or application of, electric, magnetic or wave energy, e.g. ultrasonic waves ; Ionic sputtering; Flame or plasma spraying; Particle radiation making use of electric or magnetic fields, wave energy or particle radiation
- B01J37/347—Ionic or cathodic spraying; Electric discharge
Abstract
The present invention relates to a kind of methods that Electron Beam Irradiation prepares graphite oxide alkenyl enzyme-free glucose sensor, belong to radiation chemistry and graphene nano Material Field.Graphene oxide is produced using existing known technology method first；Then it is configured to mixed solution with silver nitrate, aniline according to a certain percentage；Perchloric acid solution is added thereto again to be uniformly mixed；It is placed in electron beam generating apparatus and carries out electron beam irradiation, irradiation dose is 150~300 KGy；Then washed, dry obtained graphite oxide alkenyl enzyme-free glucose sensor.The resulting graphite oxide alkenyl enzyme-free glucose sensor of this method, good biocompatibility prove it in the case where not adding enzyme by detection, have more sensitive glucose detection activity；Preparation process is simple, at low cost, is not related to toxic substance, environmentally friendly.
Description
Technical field
The present invention relates to a kind of methods that Electron Beam Irradiation prepares graphite oxide alkenyl enzyme-free glucose sensor, belong to
Radiation chemistry and graphene nano Material Field.
Background technique
The glucose sensor of measurement Glucose in Blood by Cyclic, which is divided into, to be had enzyme and without two kinds of enzyme, there is enzymatic glucose sensor
Due to glucose oxidase itself vulnerable to extraneous factor influence be difficult to store for a long time, and enzyme-free glucose sensor then show it is good
Good electro catalytic activity.All in all, have the range of linearity wide, detection limits low, high sensitivity, and the good advantage of selectivity also has
Standby good reproducibility and long-time stability.So the exploratory development of enzyme-free glucose sensor receives universal concern.
The metals such as gold, copper, nickel bare electrode can be made into glucose sensor electrode without enzyme, but this kind of electrode is to grape glycosyloxy
Change show lower sensitivity and selectivity it is lower.Nanometer material modified electrode has biggish specific surface area and higher
Catalytic activity has been widely used in the development of enzyme-free glucose sensor.Some researches show that noble metal nano particles and mistakes
It crosses metal nano material and all has the glycoxidative activity of good catalysis grape, be the important material for constructing enzyme-free glucose sensor
Material.The electron transmission that there is graphene nano material excellent electric conductivity to promote electrode surface keeps nano particle catalysis active
It significantly increases, big specific surface area can load more nanoparticles with catalytic activity, make the detection signal of sensor
It greatly enhances.However, since the Van der Waals force between graphene sheet layer is stronger, so that the dispersibility of graphene is poor.
Currently, researcher has developed a kind of graphene oxide/polyaniline composite material.Graphene oxide/the polyphenyl
Amine composite material can apply to be built with enzymatic glucose sensor.But due to graphene oxide/polyaniline composite material system
Standby to use electrochemical synthesis and chemical synthesis, time-consuming for preparation process, cost is relatively high, technique is cumbersome, and preparation process
In need to use Strong oxdiative reagent, such as potassium peroxydisulfate can cause environmental pollution.
Summary of the invention
The purpose of the present invention is provide a kind of Electron Beam Irradiation preparation oxidation stone for the deficiencies in the prior art
The method of mertenyl enzyme-free glucose sensor, the oxidation and restore free radical that this method is generated using electron beam irradiation water, together
When silver particles and synthesized polyaniline are loaded on graphene oxide, preparation process is simple, mild condition, does not have to toxic chemical and tries
Agent, it is environmentally friendly, and glucose sensor obtained has good glucose responding.
The method that Electron Beam Irradiation of the invention prepares graphite oxide alkenyl enzyme-free glucose sensor, it is characterised in that
With following preparation process and step:
A. raw material graphene oxide is prepared
Prior art preparation raw material graphene oxide is pressed first, and preparation method is as follows:
By a certain amount of potassium peroxydisulfate (K2S2O8) and phosphorus pentoxide (P2O5) be dissolved in the concentrated sulfuric acid, after being heated to 80 DEG C
A certain amount of natural graphite is added, is cooled to room temperature after keeping the temperature 4.5 hours at 80 DEG C；Then it is diluted, is placed with deionized water
Overnight；Then it is filtered, washs, gained filter residue is put dry at 60 DEG C in a vacuum drying oven；Filter residue after drying is molten
Solution is slowly added to potassium permanganate (KMnO in the concentrated sulfuric acid under condition of ice bath4), constant temperature stirs 2 hours at 35 DEG C；Then it uses
Deionized water dilution, and it is slowly added to 30% hydrogen peroxide (H2O2)；Then it is filtered, washed, by the product after washing at 60 DEG C
Vacuum drying, obtains graphene oxide solid；
B. Electron Beam Irradiation prepares graphite oxide alkenyl enzyme-free glucose sensor
(1), it weighs the resulting graphene oxide of a certain amount of above-mentioned steps (a) to be scattered in deionized water, is placed in ultrasound
Ultrasonic disperse 5~15 minutes in oscillator mix them thoroughly uniformly, and obtaining concentration is the g/L graphene oxide of 0.5 g/L~2
Suspension；
(2), a certain amount of soluble silver salt is weighed, is dissolved in suspension obtained by above-mentioned steps (1), then be placed in sonic oscillation
Ultrasonic disperse 5~8 minutes in device mix them thoroughly uniformly, obtain the first mixed solution, the silver salt and graphene oxide
Mass concentration ratio is 1:1~1:5；
(3), the aniline of the uL of 150 uL~300 is added into resulting first mixed solution of above-mentioned steps (2), is placed in
It is stirred 20~30 minutes in magnetic stirring apparatus, is uniformly mixed it, obtains the second mixed solution；
(4), the perchloric acid solution of the mL of 4 mL~15 is added to resulting second mixed solution of above-mentioned steps (3) and is relayed
Continuous stirring, is uniformly mixed it, obtains third mixed solution；
(5), the resulting third mixed solution of above-mentioned steps (4) is put into the reaction vessel of sealing, and places it in 2.5
It is irradiated under the electron beam irradiation of the electron accelerator generation of MeV, 40 mA, irradiation dose is 150~300 KGy, is obtained
Product after irradiation reaction；
(6), with the product after the above-mentioned irradiated reaction of ethanol washing, then wash with distilled water；Then high speed centrifugation is used
Machine centrifuge separation, repeated multiple times, the solids to remove wherein unreacted ion, after being separated；
(7), the solids after above-mentioned steps (6) resulting separation is placed in a vacuum drying oven drying, drying temperature is
50 oC~80oC, drying time are 8~15 hours；Black solid object graphite oxide alkenyl enzyme-free glucose is obtained after drying
Sensor, as silver-silver chloride/polyaniline/graphene oxide enzyme-free glucose sensor.
Soluble silver salt described in above-mentioned steps (2) is one of silver nitrate and silver perchlorate.
The invention has the characteristics that generating a variety of oxidations and reproducibility using water under conditions of high-energy electron beam irradiation
Living radical, the reaction condition of the accurate control system of energy make the active free radical of a variety of oxidations and reproducibility while playing
Effect,Wherein, the aqueous electron of reductive free radical restores silver ion, and oxidative free radical, hydroxyl radical free radical make aniline polymerization
Polyaniline is generated, single step reaction prepares silver-silver chloride/polyaniline/graphene oxide enzyme-free glucose sensor.
Compared with prior art, the present invention having following remarkable advantage:
(1) preparation process of the present invention is simple, and production cost is low, is not related to toxic harmful chemical agents, ring in preparation process
Border is friendly；
(2) in preparation process of the present invention, silver-silver chloride nano particle and polyaniline energy uniform load are in graphene oxide
On, nano particle well-crystallized；Chemical property is good, and glucose sensor obtained has good glucose responding
Property, it can be used for detecting glucose under conditions of no enzyme.
Detailed description of the invention
Fig. 1 is X diffraction (XRD) figure of gained graphite oxide alkenyl enzyme-free glucose sensor in the embodiment of the present invention.
Fig. 2 is scanning electron microscope (SEM) figure of gained graphite oxide alkenyl enzyme-free glucose sensor in the embodiment of the present invention.
Fig. 3 be the embodiment of the present invention in gained graphite oxide alkenyl enzyme-free glucose sensor under no glucose condition
With there is the cyclic voltammetric under glucose condition to compare figure.
Specific embodiment
After now specific embodiments of the present invention are described in detail.
Embodiment
Producing graphene oxide by existing known technology first, (technical method can refer to document J. Am. Chem.
Soc., 2008,130 (18), 5856-5857).
1, the preparation of graphene oxide
By a certain amount of potassium peroxydisulfate (K2S2O8) and phosphorus pentoxide (P2O5) be dissolved in the concentrated sulfuric acid, after being heated to 80 DEG C
A certain amount of natural graphite is added, is cooled to room temperature after keeping the temperature 4.5 hours at 80 DEG C；Then it is diluted, is placed with deionized water
Overnight；Then it is filtered, washs, gained filter residue is put dry at 60 DEG C in a vacuum drying oven；Filter residue after drying is molten
Solution is slowly added to potassium permanganate (KMnO in the concentrated sulfuric acid under condition of ice bath4), constant temperature stirs 2 hours at 35 DEG C；Then it uses
Deionized water dilution, and it is slowly added to 30% hydrogen peroxide (H2O2)；Then it is filtered, washed, by the product after washing at 60 DEG C
Vacuum drying, obtains graphene oxide solid；
2, Electron Beam Irradiation prepares graphite oxide alkenyl enzyme-free glucose sensor
(1), the resulting graphene oxide of above-mentioned steps (a) for weighing 0.9g is scattered in 900 mL deionized waters, is placed in
Ultrasonic disperse 8 minutes in ultrasonator mix them thoroughly uniformly, and obtaining concentration is 1 g/L graphene oxide suspension；
(2), the silver nitrate for weighing 0.3 g is dissolved in suspension obtained by above-mentioned steps (1), is placed in ultrasonator
Middle ultrasonic disperse 6 minutes mixes them thoroughly uniformly, obtains the first mixed solution, the silver salt and graphene oxide quality
Concentration ratio is 1:3；
(3), the aniline of 200 uL is added to resulting first mixed solution of above-mentioned steps (2), is placed in magnetic stirring apparatus
Middle stirring 25 minutes, is uniformly mixed it, obtains the second mixed solution；
(4), the perchloric acid solution of 8 mL is added into resulting second mixed solution of above-mentioned steps (3), continues to stir,
It is uniformly mixed it, obtains third mixed solution；
(5), the resulting third mixed solution of above-mentioned steps (4) is put into the reaction vessel of sealing, and places it in 2.5
It is irradiated under the electron beam irradiation of the electron accelerator generation of MeV, 40 mA, irradiation dose is 210 KGy, is irradiated
Product after reaction；
(6), with the product after the above-mentioned irradiated reaction of ethanol washing, then wash with distilled water；Then high speed centrifugation is used
Machine centrifuge separation, repeated multiple times, the solids to remove wherein unreacted ion, after being separated；
(7), the obtained solid object after above-mentioned steps (6) separation is placed in a vacuum drying oven drying, drying temperature 70oC, drying time are 12 hours；Gained black solid object graphite oxide alkenyl enzyme-free glucose sensor after drying, as silver-
Silver chlorate/polyaniline/graphene oxide enzyme-free glucose sensor.The performance of graphite oxide alkenyl enzyme-free glucose sensor is surveyed
Examination:
The present invention tests the electrochemical sensing performance of graphite oxide alkenyl enzyme-free glucose sensor using cyclic voltammetry.
Graphite oxide alkenyl enzyme-free glucose sensor obtained in embodiment is dissolved in dehydrated alcohol, being configured to concentration is 5g/L's
Solution；It is successively polished glass-carbon electrode, is cleaned with deionized water, to its natural air drying with the sand paper of 5 μm and 2.7 μm；Take above-mentioned match
The solution drop being set to drips the perfluorinated sulfonic acid solution of 20 μ L on glass-carbon electrode, and on its surface again, at room temperature natural air drying；Group
Fill three electrode test systems, three electrodes are respectively: working electrode is glass-carbon electrode, and reference electrode is Ag/AgCl electrode, electrode
For platinum electrode；Electrolyte is prepared respectively are as follows: the sodium hydroxide of the 50mM without containing glucose and the glucose hydrogen containing 5mM
Sodium hydroxide solution；Assembled three electrode tests system is connected on CHI660C electrochemical test and is detected, according to it
The variation of response current is to realize the detection to graphite oxide alkenyl enzyme-free glucose sensor to glucose.
Referring to attached drawing, Fig. 1 is the XRD spectra of graphite oxide alkenyl enzyme-free glucose sensor obtained by the embodiment of the present invention.
XRD analysis: it is carried out on Japanese RigaKu D/max-2550 type X-ray diffractometer；Using CuK diffraction.As can be known from Fig. 1, this
The group of graphite oxide alkenyl enzyme-free glucose sensor becomes silver nano-grain, polyaniline and graphene oxide, wherein silver nanoparticle
The well-crystallized of particle.
Referring to attached drawing, Fig. 2 is the SEM figure of graphite oxide alkenyl enzyme-free glucose sensor obtained by the embodiment of the present invention.SEM
Analysis: material morphology is observed using Jeol Ltd. JSM-6700F type field emission scanning electron microscope.From Fig. 2
It is found that silver nano-grain and polyaniline are uniformly supported on graphene oxide in this graphite oxide alkenyl enzyme-free glucose sensor
On.
Referring to attached drawing, Fig. 3 is graphite oxide alkenyl enzyme-free glucose sensor obtained by the embodiment of the present invention in no glucose
Under the conditions of and there is the cyclic voltammetric under glucose condition to compare figure.As can be known from Fig. 3, glucose sensor produced by the present invention exists
In the presence of glucose, response current is significantly increased, suitable for the analysis and detection to glucose.
Claims (2)
1. a kind of method that Electron Beam Irradiation prepares graphite oxide alkenyl enzyme-free glucose sensor, it is characterised in that have with
Lower preparation process and step:
A. raw material graphene oxide is prepared
Prior art preparation raw material graphene oxide is pressed first, and preparation method is as follows:
By a certain amount of potassium peroxydisulfate (K2S2O8) and phosphorus pentoxide (P2O5) be dissolved in the concentrated sulfuric acid, it is added after being heated to 80 DEG C
A certain amount of natural graphite is cooled to room temperature after keeping the temperature 4.5 hours at 80 DEG C；Then it is diluted, is stood overnight with deionized water；
Then it is filtered, washs, gained filter residue is put dry at 60 DEG C in a vacuum drying oven；Filter residue after drying is dissolved in dense
In sulfuric acid, potassium permanganate (KMnO is slowly added under condition of ice bath4), constant temperature stirs 2 hours at 35 DEG C；Then deionization is used
Water dilution, and it is slowly added to 30% hydrogen peroxide (H2O2)；Then it is filtered, washed, by the product after washing, vacuum is done at 60 DEG C
It is dry, obtain graphene oxide solid；
B. Electron Beam Irradiation prepares graphite oxide alkenyl enzyme-free glucose sensor
(1), it weighs a certain amount of resulting graphene oxide of above-mentioned steps a to be scattered in deionized water, is placed in ultrasonator
Middle ultrasonic disperse 5~15 minutes mixes them thoroughly uniformly, and obtaining concentration is 0.5g/L~2g/L graphene oxide suspension；
(2), a certain amount of soluble silver salt is weighed, is dissolved in suspension obtained by above-mentioned steps (1), then be placed in ultrasonator
It ultrasonic disperse 5~8 minutes, mixes them thoroughly uniformly, obtains the first mixed solution, the silver salt and graphene oxide quality
Concentration ratio is 1:1~1:5；
(3), the aniline of 150 μ of μ L~300 L is added into resulting first mixed solution of above-mentioned steps (2), is placed in magnetic force and stirs
It mixes in device and stirs 20~30 minutes, be uniformly mixed it, obtain the second mixed solution；
(4), the perchloric acid solution of 4mL~15mL is added into resulting second mixed solution of above-mentioned steps (3) and continues to stir,
It is uniformly mixed it, obtains third mixed solution；
(5), the resulting third mixed solution of above-mentioned steps (4) is put into the reaction vessel of sealing, and place it in 2.5MeV,
It is irradiated under the electron beam irradiation that the electron accelerator of 40mA generates, irradiation dose is 150~300KGy, and it is anti-to obtain irradiation
Product after answering；
(6), with the product after the above-mentioned irradiated reaction of ethanol washing, then wash with distilled water；Then with supercentrifuge from
Heart separation, repeated multiple times, the solids to remove wherein unreacted ion, after being separated；
(7), the solids after above-mentioned steps (6) resulting separation is placed in a vacuum drying oven drying, drying temperature is 50 DEG C
~80 DEG C, drying time is 8~15 hours；It is silver-silver chloride/polyaniline/graphene oxide that black solid object is obtained after drying,
And using silver-silver chloride/polyaniline/graphene oxide as modified electrode material, applied to preparing enzyme-free glucose sensor.
2. the side that a kind of Electron Beam Irradiation according to claim 1 prepares graphite oxide alkenyl enzyme-free glucose sensor
Method, which is characterized in that soluble silver salt described in above-mentioned steps (2) is one of silver nitrate and silver perchlorate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610847831.1A CN106353390B (en) | 2016-09-24 | 2016-09-24 | The method that Electron Beam Irradiation prepares graphite oxide alkenyl enzyme-free glucose sensor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610847831.1A CN106353390B (en) | 2016-09-24 | 2016-09-24 | The method that Electron Beam Irradiation prepares graphite oxide alkenyl enzyme-free glucose sensor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106353390A CN106353390A (en) | 2017-01-25 |
| CN106353390B true CN106353390B (en) | 2019-06-25 |
Family
ID=57859036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610847831.1A Active CN106353390B (en) | 2016-09-24 | 2016-09-24 | The method that Electron Beam Irradiation prepares graphite oxide alkenyl enzyme-free glucose sensor |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106353390B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2796672C2 (en) * | 2022-07-19 | 2023-05-29 | Общество С Ограниченной Ответственностью "Даглитий" | Method for obtaining graphene oxide |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110711070B (en) * | 2019-09-25 | 2022-08-02 | 张小伏 | Preparation method of far infrared graphene condom |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7097906B2 (en) * | 2003-06-05 | 2006-08-29 | Lockheed Martin Corporation | Pure carbon isotropic alloy of allotropic forms of carbon including single-walled carbon nanotubes and diamond-like carbon |
| CN101559941B (en) * | 2009-05-26 | 2012-02-22 | 上海大学 | Method for preparing graphite alkenyl nanometer materials by electron beam irradiation method |
| CN101607707A (en) * | 2009-06-27 | 2009-12-23 | 兰州大学 | Adopt electronic beam irradiation technology to prepare the method for Graphene |
| JP2012076958A (en) * | 2010-09-30 | 2012-04-19 | Sekisui Chem Co Ltd | Graphene composite material and method for producing graphene composite sheet |
| CN102408109B (en) * | 2011-08-23 | 2013-07-24 | 中国科学院上海应用物理研究所 | Reduced graphene oxide and preparation method thereof |
| CN102432095A (en) * | 2011-10-28 | 2012-05-02 | 上海大学 | Method for degrading clopyralid in water by performing electron beam irradiation |
-
2016
- 2016-09-24 CN CN201610847831.1A patent/CN106353390B/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2796672C2 (en) * | 2022-07-19 | 2023-05-29 | Общество С Ограниченной Ответственностью "Даглитий" | Method for obtaining graphene oxide |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106353390A (en) | 2017-01-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Chen et al. | Preparation of highly sensitive Pt nanoparticles-carbon quantum dots/ionic liquid functionalized graphene oxide nanocomposites and application for H2O2 detection | |
| Soomro et al. | Electrochemical sensing of glucose based on novel hedgehog-like NiO nanostructures | |
| Liu et al. | A novel non-enzymatic electrochemical biosensor based on the nanohybrid of bimetallic PdCu nanoparticles/carbon black for highly sensitive detection of H2O2 released from living cells | |
| Shu et al. | Single-step electrochemical deposition of high performance Au-graphene nanocomposites for nonenzymatic glucose sensing | |
| Ge et al. | Electrochemical K-562 cells sensor based on origami paper device for point-of-care testing | |
| Zou et al. | Vertically-ordered mesoporous silica films grown on boron nitride-graphene composite modified electrodes for rapid and sensitive detection of carbendazim in real samples | |
| Song et al. | A hollow urchin-like α-MnO 2 as an electrochemical sensor for hydrogen peroxide and dopamine with high selectivity and sensitivity | |
| Bairagi et al. | Electro-polymerized polyacrylamide nano film grown on a Ni-reduced graphene oxide-polymer composite: A highly selective non-enzymatic electrochemical recognition element for glucose | |
| Rafati et al. | Amperometric sensing of anti-HIV drug zidovudine on Ag nanofilm-multiwalled carbon nanotubes modified glassy carbon electrode | |
| Tian et al. | Amperometric detection of glucose based on immobilizing glucose oxidase on g-C3N4 nanosheets | |
| Chen et al. | Specific detection of monosaccharide by dual-channel sensing platform based on dual catalytic system constructed by bio-enzyme and bionic enzyme using molecular imprinting polymers | |
| Li et al. | Porous NiTe2 nanosheet array: An effective electrochemical sensor for glucose detection | |
| CN107153089A (en) | A kind of preparation method of dendroid nano-complex Doxorubicin electrochemical sensor | |
| Luan et al. | Ni3S2/ionic liquid-functionalized graphene as an enhanced material for the nonenzymatic detection of glucose | |
| Govindasamy et al. | Polyaniline/nickel composite film modified electrode for sensitive electrochemical determination of ascorbic acid | |
| Li et al. | Facile preparation of novel Pd nanowire networks on a polyaniline hydrogel for sensitive determination of glucose | |
| Liu et al. | Electrochemical sensor based on laser-induced preparation of MnOx/rGO composites for simultaneous recognition of hydroquinone and catechol | |
| Wang et al. | A novel β-cyclodextrin functionalized reduced graphene oxide electrochemical sensor for blood glucose detection | |
| CN105021672B (en) | PhotoelectrochemicalMethod Method detection dopamine based on in-situ oxidation reduction reaction | |
| Sivasakthi et al. | Green synthesis of porous carbon nanocubes accumulated microspheres for the simultaneous non-enzymatic sensing of uric acid and dopamine in the presence of ascorbic acid | |
| Huang et al. | Ultrasensitive determination of metronidazole using flower-like cobalt anchored on reduced graphene oxide nanocomposite electrochemical sensor | |
| Abbasi et al. | Non-enzymatic electroanalytical sensing of glucose based on nano nickel-coordination polymers-modified glassy carbon electrode | |
| CN103399070A (en) | Preparation method of high-sensitivity electrochemical sensors for glucose detection based on nickel hydroxide and glucose oxidase | |
| CN106353390B (en) | The method that Electron Beam Irradiation prepares graphite oxide alkenyl enzyme-free glucose sensor | |
| Vahid et al. | X-Fe2O4-buckypaper-chitosan nanocomposites for nonenzymatic electrochemical glucose biosensing |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |