CN106344790A - Pill drug for treating insomnia caused by deficiency of heart-qi and gallbladder-qi and preparation method thereof - Google Patents

Abstract

The invention belongs to the field of Chinese material medical preparation, and provides a pill drug for treating insomnia caused by deficiency of heart-qi and gallbladder-qi according to the knowledge mechanism of traditional Chinese medicine on insomnia caused by deficiency of heart-qi and gallbladder-qi. The Chinese material medical preparation is prepared from, by weight, cinnabar, angelica, poria, rhizoma pinelliae, codonopsis pilosula, longan pulp, amber, spina date seed, semen boitae, albizia flower, bupleurum, gardenia, polygala, licorice, draconic dents, acorus gramineus, ginseng, poria with hostwood, atractylodes, radix ophiopogonis, radix paeoniae alba, caulis, gentian, and mother of pearl. The drug provided by the invention is a good traditional Chinese medicine formula.

Description

A kind of treat pill medicine of insomnia that the heart and gallbladder deficiency of vital energy causes and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese is and in particular to a kind of pill medicine treating the insomnia that the heart and gallbladder deficiency of vital energy causes, The field of the pill medicine particularly using for the insomniac that the heart and gallbladder deficiency of vital energy causes and preparation method thereof.

Background technology

There is limitation to the understanding of insomnia in clinical medicine science now, but, Therapist have begun to basis Clinical research, is defined to insomnia, and neurological branch of Chinese Medical Association sleep disorder group is followed according to existing within 2012 Card medical evidence, has formulated " Chinese Adult have a sleepless night Clinics and Practices guide ", wherein insomnia refer to patient to the length of one's sleep and (or) quality is unsatisfactory for and affects a kind of subjective experience of social function in the daytime.

So, with regard to how to find a kind of can the Chinese medicine composition of insomnia that causes of the effectively treatment above-mentioned heart and gallbladder deficiency of vital energy, be me Current problem in urgent need to solve.

Content of the invention

With the continuous development of China's Chinese medicine, in the insomnia that the treatment heart and gallbladder deficiency of vital energy causes, people gradually realize The advantage having arrived the insomnia that the Chinese traditional treatment heart and gallbladder deficiency of vital energy causes, and good effect, instant effect, toxic and side effects are little etc. over the course for the treatment of Advantage, the present situation of the insomnia causing for the existing western medical treatment heart and gallbladder deficiency of vital energy, the purpose of the present invention is to be to provide a kind for the treatment of The pill medicine of the insomnia that the heart and gallbladder deficiency of vital energy causes, to solve insomniac's restorative problem early that the heart and gallbladder deficiency of vital energy causes. This medicine is with common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, can the effectively treatment heart and gallbladder deficiency of vital energy draw The insomnia rising.

For reaching the purpose of foregoing invention, the technical solution adopted in the present invention is: provides one kind to treat the heart and gallbladder deficiency of vital energy and draws Pill medicine of insomnia rising and preparation method thereof is it is characterised in that each component of described medicine and its mass parts ratio are as follows Shown.

Radix Angelicae Sinensis 80～160g, Cinnabaris 1～5g, Poria 100～160g, Rhizoma Pinelliae Preparatum 30～90g, Radix Codonopsis 60～160g, Arillus Longan Meat 100～160g, succinum 15～30g, Semen Ziziphi Spinosae 60～160g, Bai Ren 100～160g, Flos Albiziae 30～100g, Radix Bupleuri 30～ 120g, Fructus Gardeniae 60～100g, Radix Polygalae 50～120g, Radix Glycyrrhizae 30～160g, Dens Draconiss 100～160g, Rhizoma Acori Graminei 30～60g, Radix Ginseng 30～120g, Poria cum Radix Pini 90～160g, the Rhizoma Atractylodis Macrocephalae 30～160g, 60～160g Radix Ophiopogonis, the Radix Paeoniae Alba 100～200g, Caulis Polygoni Multiflori 100～ 200g, Radix Gentianae 30～60g, Concha Margaritifera 100～300g.

A kind of treat pill medicine of insomnia that the heart and gallbladder deficiency of vital energy causes and preparation method thereof it is characterised in that described medicine Each component and its mass parts than as follows:

Radix Angelicae Sinensis 90～140g, Cinnabaris 2～4g, Poria 115～140g, Rhizoma Pinelliae Preparatum 40～80g, Radix Codonopsis 70～140g, Arillus Longan 115 ～140g, succinum 18～25g, Semen Ziziphi Spinosae 70～140g, Bai Ren 115～140g, Flos Albiziae 40～85g, Radix Bupleuri 40～105g, Fructus Gardeniae 70～85g, Radix Polygalae 60～105g, Radix Glycyrrhizae 40～140g, Dens Draconiss 115～140g, Rhizoma Acori Graminei 40～50g, Radix Ginseng 40～ 105g, Poria cum Radix Pini 100～140g, the Rhizoma Atractylodis Macrocephalae 40～140g, 70～140g Radix Ophiopogonis, the Radix Paeoniae Alba 115～170g, Caulis Polygoni Multiflori 115～170g, dragon Radix Gentianae 40～50g, Concha Margaritifera 115～170g.

It is a kind of that to treat pill medicine of insomnia that the heart and gallbladder deficiency of vital energy causes and preparation method thereof it is characterised in that described " optimal Each component of the medicine of scheme " and its mass parts are than as follows:

Radix Angelicae Sinensis 120g, Cinnabaris 3g, Poria 120g, Rhizoma Pinelliae Preparatum 70g, Radix Codonopsis 120g, Arillus Longan 120g, succinum 22g, Semen Ziziphi Spinosae 120g, Bai Ren 120g, Flos Albiziae 75g, Radix Bupleuri 90g, Fructus Gardeniae 75g, Radix Polygalae 90g, Radix Glycyrrhizae 120g, Dens Draconiss 120g, Rhizoma Acori Graminei 45g, Radix Ginseng 90g, Poria cum Radix Pini 120g, Rhizoma Atractylodis Macrocephalae 120g, 120g Radix Ophiopogonis, Radix Paeoniae Alba 150g, Caulis Polygoni Multiflori 150g, Radix Gentianae 45g, Concha Margaritifera 150g.

A kind of treat pill medicine of insomnia that the heart and gallbladder deficiency of vital energy causes and preparation method thereof it is characterised in that methods described Comprise the steps to be prepared from:

A, above-mentioned raw materials Chinese medicine is picked after impurity and dust, be ground into superfine end according to mass parts ratio stand-by；

B, the method preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing is sieved, put into mixing in medicine device Mix all, be then prepared into watered pill (granularity of its watered pill is: 4.7mm-4.8mm), and then dry, sealed packaging.

A kind of treat pill medicine of insomnia that the heart and gallbladder deficiency of vital energy causes and preparation method thereof it is characterised in that described take Method is: by the watered pill preparing medicine twice a day to take, sooner or later services once, dosage 3g/ time, meal one hour after Clothes, after treating 14～21 days, symptom disappears, and disease obtains recovery from illness.

Each raw material Chinese medicine in prescription of the present invention all has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.It is raw material that the present invention selects most common of which Chinese medicine, gives full play to the pharmacological effect of each component:

Radix Angelicae Sinensis, nature and flavor: warm in nature, sweet in the mouth is pungent, there is the effect of benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation, for treat blood deficiency, Shallow complexion, dizziness palpitaition, blood deficiency or have concurrently the stagnant menoxenia of the stasis of blood, amenorrhea, dysmenorrhea, deficient cold type stomachache, the coronary heart disease heart twist Bitterly, the disease such as rheumatic arthralgia, traumatic injury；

Cinnabaris, nature and flavor: sweet, be slightly cold, poisonous, there is relieving convulsion, merit of removing toxic substances of the calming the nerves effect that clears away heart-fire, for treating palpitation and being susceptible to fright, insomnia Dreaminess, epilepsy are gone mad, infantile convulsion, blurring of vision, aphtha, sore throat, sore swollen toxin；

Poria, nature and flavor: sweet, light, flat, there is the effect of eliminating dampness and diuresises, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming, for treat dysuria, Oedema turgor, phlegm retention cough with dyspnea, vomiting, spleen eating less, have loose bowels, palpitation and restlessness, insomnia forgetfulness, the seminal emission disease such as nebulousurine；

Rhizoma Pinelliae Preparatum, nature and flavor: pungent, warm, the effect of there is drying dampness to eliminate phlegm, for treating abundant expectoration cough and asthma, phlegm retention anti-dazzle nervous, dizziness due to wind-phlegm, The diseases such as phlegm and headache；

Radix Codonopsis, nature and flavor: sweet in the mouth, mild-natured, there is the effect of strengthening the spleen and tonifying the lung, supplementing QI for promoting the production of body fluid, for treating weakness of the spleen and stomach, lack of appetite just Half congealed, limbs fatigue, the deficiency of the lung are breathed with cough, shortness of breath spontaneous perspiration, feeble QI two lose all cards；

Arillus Longan, nature and flavor: sweet, warm, there is the effect of reinforcing the heart spleen, replenishing QI and blood, tranquilizing mind, for treating deficiency of both the heart and spleen, QI and blood not Palpitation with fear caused by foot, palpitation with a distress feeling, insomnia, forgetful, blood deficiency and yellow complexion, have through diseases such as uncomfortable, metrorrhagias；

Succinum, nature and flavor: sweet, flat, nontoxic, there is the effect of tranquillizing the mind by relieving convulsion, dissipate stasis of blood hemostasis, relieving stranguria by diuresis, removing nebula improving eyesight, be used for controlling Treat insomnia of palpitating with fear, infantile convulsion epilepsy, stranguria with blood hematuria, amenorrhea due to stagnation of blood, stasis of blood in puerperal, abdominal mass is gathered, mesh life is hidden from view, carbuncle skin ulcer Poison；

Semen Ziziphi Spinosae, nature and flavor: sweet, flat, there is the effect of mind tranquilizing and the heart calming, nourishing the liver, arresting sweating, for treat restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, The diseases such as body void spontaneous perspiration, night sweat；

Bai Ren, nature and flavor: sweet, mild-natured, there is the effect of tranquilizing by nourishing the heart, arresting sweating, loosening bowel to relieve constipation, for treatment palpitation with fear palpitation with a distress feeling, insomnia The forgetful, disease such as night sweat, dry constipation of intestines；

Flos Albiziae, nature and flavor: sweetness and bitterness, flat, nontoxic, there is the effect of resolving stagnation for tranquilization, qi-regulating appetizing, pathogenic wind expelling improving eyesight, promoting blood circulation and stopping pain, use In the melancholy insomnia for the treatment of, indigestion and loss of appetite, wind-fire ophthalmic, blurring of vision, lumbago, traumatic pain uncomfortable in chest；

Radix Bupleuri, nature and flavor: bitter in the mouth, pungent, cold nature, having induces sweat brings down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, rise the effect of lift yang-energy, outer for treating Sense heating, alternate attack of chill and fever, malaria, hypochondriac pain due to stagnation of liverQI mammary swelling, have a headache dizziness, menoxenia, the proctoptosis of collapse of QI, uterine prolapse, The diseases such as gastroptosis；

Fructus Gardeniae, nature and flavor: bitter, cold, there is the effect of fruit, purging intense heat relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, for treating the calentura heart Tired, jaundice urine is red, blood strangury and dry pain, blood-head tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles, external treatment bruise pain root, eliminating fire and detoxication, heat clearing away Dampness removing, cool the blood dissipate blood stasis, be used for the disease such as infectious hepatitis, traumatic injury, acute toothache；

Radix Polygalae, nature and flavor: pungent, bitter, slightly warm in nature, there is mind tranquilizing and the heart calming, eliminating the phlegm is had one's ideas straightened out, removing toxic substances and promoting subsidence of swelling the effect of, for treating the mind The disease such as uneasiness, insomnia of palpitating with fear, forgetful, infantile convulsion, cough with copious phlegm, carbuncle carbuncle on the back, breast swell and pain；

Radix Glycyrrhizae, nature and flavor: sweet, flat, there is the effect of invigorating middle warmer and replenishing QI, relieving spasm to stop pain, nourishing the lung to arrest cough, eliminating fire and detoxication, coordinating the actions of various ingredients in a prescription, use In treatment asthenia lack of appetite, leanness yellowish complexion, shortness of breath and palpitation, stomachache loose stool, four limbs contraction, hysteria, cough and asthma, swelling throat Bitterly, ulcerative carbuncle swell and ache, infantile carbuncle and the disease such as medicine, alimentary toxicosis；

Dens Draconiss, nature and flavor: puckery, sweet, cool, there is the effect of tranquillizing the mind by relieving convulsion, clearing heat and relieving fidgetness, seized with terror for treating infantile convulsion, demented, cardiopalmus The disease such as sad, insomnia and dreamful sleep, fever of the body be vexed；

Rhizoma Acori Graminei, nature and flavor: acrid in the mouth, hardship, slightly warm in nature, there is the effect of waking up the patient from unconsciousness by dissipating phlegm, removing dampness circulation of qi promoting, wind-dispelling profit numbness, reducing swelling and alleviating pain, For treating calentura coma, syncope due to accumulation of phlegm, forgetful, tinnitus, deafness, abdominal distention, fasting dysentery, rheumatic arthralgia, traumatic injury, carbuncle scabies The diseases such as tinea；

Radix Ginseng, nature and flavor: bitter in the mouth, slight bitter, slightly warm in nature, the effect of there is strongly invigorating primordial QI, invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, calm the nerves beneficial short, For treating that impairment caused by overstrain is deficient, lack of appetite, asthenia, regurgitation tell food, stool lingering diarrhea, empty cough with asthma rush, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness Headache, sexual impotence, frequent micturition, quench one's thirst, woman uterine bleeding, children's intermittent infantile convulsion, prolonged deficiency are multiple, qi-blood-body fluid deficiency the disease such as demonstrate,prove；

Poria cum Radix Pini, nature and flavor: the heart, spleen channel, have mind calming, calm the nerves, diuretic the effect of, for treatment palpitation with fear, forgetful, forgetful insomnia, shy The diseases such as epilepsy, dysuria；

The Rhizoma Atractylodis Macrocephalae, nature and flavor: bitter in the mouth, sweet, warm in nature, have invigorating the spleen and benefiting QI, eliminate dampness and have diuretic effect, hidroschesis, antiabortive the effect of, for treating temper The few abdominal distention of weakness, spiritlessness and weakness, lack of appetite, big loose stool are thin, fluid-retention stagnating in the interior, dysuria, edema, dizziness due to fluid-retention, warm numbness are ached, gas The diseases such as empty spontaneous perspiration, frequent fetal movement；

Radix Ophiopogonis, nature and flavor: sweet, slight bitter, cold, there is the effect of nourishing YIN and moistening the lung, reinforcing stomach reg fluid, relieving restlessness that clears away heart-fire, do for treating the dryness of the lung Cough, lung abscess, deficiency of YIN chronic cough, injury thirst, quench one's thirst, vexed insomnia, have sore throat, the disease such as dry constipation of intestines, blood-head tells nosebleed；

The Radix Paeoniae Alba, nature and flavor: picric acid, cool, have nourishing blood to suppress the hyperactive liver, slow in pain relieving, yin fluid astringing the effect of receive antiperspirant, for treating chest and abdomen side of body rib pain Bitterly, diarrhea dysentery abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, the inferior disease of band；

Caulis Polygoni Multiflori, nature and flavor: sweet, slight bitter, mild-natured, there is the effect of tranquilizing by nourishing the heart, wind-dispelling, dredging collateral, for treatment insomnia, dreaminess, The diseases such as blood deficiency general pain, numbness of the skin, rheumatic arthralgia, rubella itch；

Radix Gentianae, nature and flavor: bitter, cold, there is heat clearing and damp drying, eliminating pathogen in the liver gallbladder effect of fire, for treat jaundice due to damp-heat, swelling of the vulva pudendal pruritus, The diseases such as leukorrhagia, persistent erection of the penis, eczema itch, conjunctival congestion, deafness, hypochondriac pain, bitter taste, convulsion with spasms；

Concha Margaritifera, nature and flavor: sweet in the mouth, salty, cold in nature, have suppressing the hyperactive liver and subsiding YANG, calm the nerves arresting convulsion, liver heat removing and eyesight improving the effect of, for treatment head The diseases such as pain dizziness, palpitation and insomnia, demented infantile convulsion, the hot hot eyes of liver, pterygium.

Medicine of the present invention is the differential diagnosis of diseases of the insomnia being caused based on the Chinese traditional treatment heart and gallbladder deficiency of vital energy and the dialectical principle combining, from Pharmacological action and mechanism of action are thought: the insomnia causing with regard to the heart and gallbladder deficiency of vital energy, each raw material Chinese medicine in medicine provided by the present invention Drug effect is played altogether, and the insomnia that the above-mentioned heart and gallbladder deficiency of vital energy is caused has good therapeutic effect.

Specific embodiment

The present invention is aiming at the treatment of insomnia that the above-mentioned heart and gallbladder deficiency of vital energy causes and a kind of Chinese medicine formula proposing, using this The medicine effect of formula preparation is good, and instant effect is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice.Tie below The specific embodiment closing the present invention is described in further detail.

Embodiment 1:

A kind of pill medicine treating the insomnia that the heart and gallbladder deficiency of vital energy causes is it is characterised in that each component of described medicine and its matter Amount part is than as follows:

Radix Angelicae Sinensis 120g, Cinnabaris 3g, Poria 120g, Rhizoma Pinelliae Preparatum 70g, Radix Codonopsis 120g, Arillus Longan 120g, succinum 22g, Semen Ziziphi Spinosae 120g, Bai Ren 120g, Flos Albiziae 75g, Radix Bupleuri 90g, Fructus Gardeniae 75g, Radix Polygalae 90g, Radix Glycyrrhizae 120g, Dens Draconiss 120g, Rhizoma Acori Graminei 45g, Radix Ginseng 90g, Poria cum Radix Pini 120g, Rhizoma Atractylodis Macrocephalae 120g, 120g Radix Ophiopogonis, Radix Paeoniae Alba 150g, Caulis Polygoni Multiflori 150g, Radix Gentianae 45g, Concha Margaritifera 150g.

Embodiment 2:

A kind of pill medicine treating the insomnia that the heart and gallbladder deficiency of vital energy causes is it is characterised in that each component of described medicine and its matter Amount part is than as follows:

Radix Angelicae Sinensis 140g, Cinnabaris 4g, Poria 140g, Rhizoma Pinelliae Preparatum 80g, Radix Codonopsis 140g, Arillus Longan 140g, succinum 25g, Semen Ziziphi Spinosae 140g, Bai Ren 140g, Flos Albiziae 85g, Radix Bupleuri 105g, Fructus Gardeniae 85g, Radix Polygalae 105g, Radix Glycyrrhizae 140g, Dens Draconiss 140g, Rhizoma Acori Graminei 50g, Radix Ginseng 105g, Poria cum Radix Pini 140g, Rhizoma Atractylodis Macrocephalae 140g, 140g Radix Ophiopogonis, Radix Paeoniae Alba 170g, Caulis Polygoni Multiflori 170g, Radix Gentianae 50g, Concha Margaritifera 170g.

Embodiment 3:

A kind of pill medicine treating the insomnia that the heart and gallbladder deficiency of vital energy causes is it is characterised in that each component of described medicine and its matter Amount part is than as follows:

Radix Angelicae Sinensis 160g, Cinnabaris 5g, Poria 160g, Rhizoma Pinelliae Preparatum 90g, Radix Codonopsis 160g, Arillus Longan 160g, succinum 30g, Semen Ziziphi Spinosae 160g, Bai Ren 160g, Flos Albiziae 100g, Radix Bupleuri 120g, Fructus Gardeniae 100g, Radix Polygalae 120g, Radix Glycyrrhizae 160g, Dens Draconiss 160g, Rhizoma Acori Graminei 60g, Radix Ginseng 120g, Poria cum Radix Pini 160g, Rhizoma Atractylodis Macrocephalae 160g, 160g Radix Ophiopogonis, Radix Paeoniae Alba 200g, Caulis Polygoni Multiflori 200g, Radix Gentianae 60g, Concha Margaritifera 300g.

Model case

The insomniac totally 835 causing through the clinical conditions heart and gallbladder deficiency of vital energy, the age is 425 of more than 32 years old, only 410 Example is less than 32 years old.805 of recovery from illness in 835 patients, effective 35, total effective rate reaches 100%.

Claims (3)

1. a kind of pill medicine treating the insomnia that the heart and gallbladder deficiency of vital energy causes it is characterised in that each component of described medicine and its Mass parts are than as follows:

Radix Angelicae Sinensis 80～160g, Cinnabaris 1～5g, Poria 100～160g, Rhizoma Pinelliae Preparatum 30～90g, Radix Codonopsis 60～160g, Arillus Longan 100 ～160g, succinum 15～30g, Semen Ziziphi Spinosae 60～160g, Bai Ren 100～160g, Flos Albiziae 30～100g, Radix Bupleuri 30～120g, Fructus Gardeniae 60～100g, Radix Polygalae 50～120g, Radix Glycyrrhizae 30～160g, Dens Draconiss 100～160g, Rhizoma Acori Graminei 30～60g, Radix Ginseng 30～ 120g, Poria cum Radix Pini 90～160g, the Rhizoma Atractylodis Macrocephalae 30～160g, 60～160g Radix Ophiopogonis, the Radix Paeoniae Alba 100～200g, Caulis Polygoni Multiflori 100～200g, dragon Radix Gentianae 30～60g, Concha Margaritifera 100～300g.

2. the treatment heart and gallbladder deficiency of vital energy according to claim 1 causes the pill medicine of insomnia is it is characterised in that described medicine Each component and its mass parts than as follows:

Radix Angelicae Sinensis 90～140g, Cinnabaris 2～4g, Poria 115～140g, Rhizoma Pinelliae Preparatum 40～80g, Radix Codonopsis 70～140g, Arillus Longan 115 ～140g, succinum 18～25g, Semen Ziziphi Spinosae 70～140g, Bai Ren 115～140g, Flos Albiziae 40～85g, Radix Bupleuri 40～105g, Fructus Gardeniae 70～85g, Radix Polygalae 60～105g, Radix Glycyrrhizae 40～140g, Dens Draconiss 115～140g, Rhizoma Acori Graminei 40～50g, Radix Ginseng 40～ 105g, Poria cum Radix Pini 100～140g, the Rhizoma Atractylodis Macrocephalae 40～140g, 70～140g Radix Ophiopogonis, the Radix Paeoniae Alba 115～170g, Caulis Polygoni Multiflori 115～170g, dragon Radix Gentianae 40～50g, Concha Margaritifera 115～170g.

3. the treatment heart and gallbladder deficiency of vital energy according to claim 1 to 2 causes the pill medicine of insomnia is it is characterised in that described Each component of Chinese medicine composition and its mass parts are than as follows:

Radix Angelicae Sinensis 120g, Cinnabaris 3g, Poria 120g, Rhizoma Pinelliae Preparatum 70g, Radix Codonopsis 120g, Arillus Longan 120g, succinum 22g, Semen Ziziphi Spinosae 120g, Bai Ren 120g, Flos Albiziae 75g, Radix Bupleuri 90g, Fructus Gardeniae 75g, Radix Polygalae 90g, Radix Glycyrrhizae 120g, Dens Draconiss 120g, Rhizoma Acori Graminei 45g, Radix Ginseng 90g, Poria cum Radix Pini 120g, Rhizoma Atractylodis Macrocephalae 120g, 120g Radix Ophiopogonis, Radix Paeoniae Alba 150g, Caulis Polygoni Multiflori 150g, Radix Gentianae 45g, Concha Margaritifera 150g.