CN106344694A - Medicine for treating hypertension and hyperlipidemia and preparation method thereof - Google Patents
Medicine for treating hypertension and hyperlipidemia and preparation method thereof Download PDFInfo
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- CN106344694A CN106344694A CN201610955700.5A CN201610955700A CN106344694A CN 106344694 A CN106344694 A CN 106344694A CN 201610955700 A CN201610955700 A CN 201610955700A CN 106344694 A CN106344694 A CN 106344694A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/754—Evodia
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Abstract
The invention discloses a medicine for treating hypertension and hyperlipidemia and a preparation method thereof. The medicine comprises the following raw materials in parts by weight: 12-25 parts of pseudo-ginseng flower, 12-28 parts of semen cassiae, 13-30 parts of aleppo avens, 13-32 parts of prepared coptis chinensis, 11-28 parts of fructus evodiae, 12-28 parts of uncaria roots and 15-25 parts of scorched hawthorn. The preparation method comprises the following steps: sampling in parts by weight, and then putting raw hawthorn into a pan, frying to black with strong fire, taking out, and cooling for later use; putting raw semen cassia into a processing machine, frying to yellow till having fragrance, taking out, and cooling for later use; cleaning the other five medicines, removing impurities, and drying for later use; and mixing the prepared seven medicines in parts by weight, crushing and sieving with a 100-140 mesh sieve, sterilizing and disinfecting, thereby obtaining the medicine. The medicine for treating hypertension and hyperlipidemia has excellent functions of preventing and treating hypertension and hyperlipidemia; the pharmacological effect is accurate; the medicine is free from toxic or side effect, and is safe and reliable; the preparation method is simple and the use is convenient; and on the basis of analysis for 255 clinic treatment cases, the total effective rate is 94%.
Description
Technical field
The invention belongs to technical field of Chinese medicines, relate in particular to a kind of medicine treating hypertension, hyperlipidemia, also simultaneously
It is related to its preparation method.
Background technology
Hypertension (hypertension) refers to increase as main with systemic arterial blood pressure (systolic pressure and/or diastolic pressure)
Feature (systolic pressure >=140 millimetres of mercury, diastolic pressure >=90 millimetres of mercury), can be with the function of the organs such as the heart, brain, kidney or device matter
Property infringement clinical syndrome.Hypertension is modal chronic disease, is also the topmost risk factor of cardiovascular and cerebrovascular disease.Normally
The blood pressure of people fluctuates within the specific limits with internal and external environment change.In overall crowd, blood pressure level gradually rose with the age, to receive
Contractive pressure becomes apparent from, but after 50 years old, diastolic pressure assumes downward trend, and pulse pressure also increases therewith.
Hyperlipemia can be divided into constitutional and Secondary cases two class.Constitutional is relevant with congenital and heredity, is due to single base
Because of defect or polygenes defect, make receptor, enzyme or the apolipoprotein caused by abnormal of the transhipment of participation lipoprotein and metabolism, or due to ring
Border factor (diet, nutrition, medicine) and being caused by unknown mechanism.Secondary cases are multiple to be born in metabolic disorder disease (glycosuria
Disease, hypertension, myxedema, hypothyroidism, obesity, hepatorenal disease, adrenal cortex function are hyperfunction), or and its
His factor age, sex, season, drink, smoking, diet, physical exertion, psychentonia, emotional activity etc. relevant.Treat high fat
The medicine of mass formed by blood stasis has Statins and resinae to reduce based on serum total cholesterol and ldl cholesterol.To reduce serum trigalloyl
Medicine based on glycerol has fibrates and nicotinic acid class.
Tradition prevents and treats hypertension, hyperlipidemia be by Western medicine blood pressure lowering blood fat reducing be target.It is typically only capable to control blood pressure, once
Drug withdrawal blood pressure will go up again, not have the effect fundamentally treated, and can induce various acute and chronic complication, ultimately result in machine
Body is permitted multi-functional forfeiture, or even threat to life.The great mass of data of medical circle shows, as long as treating through rational, great majority
The blood pressure of patient can be with stability contorting in normal value, and this point adopts tcm therapy effect very preferable.In hyperlipidemia and high blood
Drug treatment employed in pressure treatment, generally has larger toxic and side effects, may cause secondary injury to patient, and
Drug dependence is strong.At present, also much Chinese patent medicines for hyperlipidemia and hypertension therapeutic in market, but curative effect is irregular not
Together.
Content of the invention
It is an object of the invention to provide the treatment hypertension of a kind of good effect, Small side effects, the medicine of hyperlipidemia.
Another object of the present invention is to providing the preparation method of this medicine.
A kind of medicine treating hypertension, hyperlipidemia of the present invention, including the raw material of following weight parts:
Flower of Radix Notoginseng 12-25 part, Semen Cassiae 12-28 part, Radix seu Herba Gei aleppici 13-30 part, Rhizoma Coptidis (processed) 13-32 part, Fructus Evodiae 11-28 part, hook
Rattan root 12-28 part, Fructus Crataegi (parched to brown) 15-25 part.
A kind of above-mentioned medicine treating hypertension, hyperlipidemia, preferably each parts by weight of raw materials is as follows:
12 parts of flower of Radix Notoginseng, 15 parts of Semen Cassiae, 13 parts of Radix seu Herba Gei aleppici, 13 parts of Rhizoma Coptidis (processed), 11 parts of Fructus Evodiae, 15 parts of Radix Uncariae rhynchophyllae, Fructus Crataegi (parched to brown)
15 parts.
A kind of preparation method of above-mentioned medicine treating hypertension, hyperlipidemia, comprises the steps:
(1) take by weight: flower of Radix Notoginseng 12-25 part, Semen Cassiae 12-28 part, Radix seu Herba Gei aleppici 13-30 part, Rhizoma Coptidis (processed) 13-32 part, Wu
Fructus Evodiae 15-28 part, Radix Uncariae rhynchophyllae 12-28 part, Fructus Crataegi (parched to brown) 15-25 part；
(2) Fructus Crataegi is put into and fry with high heat in pot to black, take out cool cold standby；
(3) raw Semen Cassiae is put into parching to brown in processing machine and, to savory, take out cool cold standby；；
(4) remaining 5 taste medicine is cleaned and remove impurity, dry for standby；
(5), after the above-mentioned 7 taste medicines processing being mixed by weight, pulverized 100-140 mesh sieve, after sterilizing, obtained final product.
The medicine of the present invention compared with prior art, has clear advantage and effect, from above technical scheme: this
Invention is raw material from flower of Radix Notoginseng, Semen Cassiae, Radix seu Herba Gei aleppici, Rhizoma Coptidis (processed), Fructus Evodiae, Radix Uncariae rhynchophyllae, Fructus Crataegi (parched to brown), by the association of each medicine
Same-action, to treat hyperlipidemia and hypertension, has the effect of liver heat removing function of gallbladder promoting, heat-clearing and toxic substances removing, invigorating the spleen for eliminating dampness, can effectively reduction blood fat,
Blood pressure level, cooperation diet control and motor adjustment, can make Most patients recover normal.To 1 type, 2 types, the high blood of constitutional
Pressure, secondary hypertension, Primary hyperlipemia, Secondary Hyperlipidemia have good preventive and therapeutic action.Its drug effect is true
Cut, have no toxic side effect, safe and reliable, preparation method is simple, easy to use.Clinical treatment case 255, total effective rate 94%.
Specific embodiment
The beneficial effect of of the present invention medicine is expanded on further below by way of test example.
Test example: the clinical observation of medicine of the present invention
1st, case selection
Treatment case 255, wherein: one full year of life at age 8-85, man 154, female 101.
2nd, Disease Diagnosis Standard
" disease of tcm Standardization of diagnosis and curative effect ".
3rd, Therapeutic Method:
Take the medicine prepared by the embodiment of the present invention, three times a day, each 1.2g, boiled water is taken after mixing it with water, and is within 30 days a course for the treatment of, 10-
30 days take effect.
4th, curative effect determinate standard
Effective: symptomatology substantially eliminates or cardinal symptom eliminates；
Effective: cardinal symptom substantially eliminates or is obviously improved；
Invalid: various symptoms and sign no change.
5th, therapeutic outcome:
Whole 255 patients use medicine of the present invention, wherein fully recover 93, effective 147, invalid 15, total effective rate 94%.
Illustrate the preparation method of this medicine by following examples.
Embodiment 1:
A kind of preparation method of the medicine treating hypertension, hyperlipidemia, comprises the steps:
(1) weigh: flower of Radix Notoginseng 12g, Semen Cassiae 28g, Radix seu Herba Gei aleppici 13g, Rhizoma Coptidis (processed) 32g, Fructus Evodiae 11g, Radix Uncariae rhynchophyllae 28g, Jiaoshan Hill
Short, bristly hair or beard 15g；
(2) Fructus Crataegi is put into and fry with high heat in pot to black, take out cool cold standby；
(3) raw Semen Cassiae is put into parching to brown in processing machine and, to savory, take out cool cold standby；；
(4) remaining 5 taste medicine is cleaned and remove impurity, dry for standby；
(5) by after the above-mentioned 7 taste medicine mixing processing, pulverized 100 mesh sieves, after sterilizing, obtained final product.
Embodiment 2:
A kind of preparation method of the medicine treating hypertension, hyperlipidemia, comprises the steps:
(1) weigh: flower of Radix Notoginseng 20g, Semen Cassiae 15g, Radix seu Herba Gei aleppici 20g, Rhizoma Coptidis (processed) 25g, Fructus Evodiae 22g, Radix Uncariae rhynchophyllae 20g, Jiaoshan Hill
Short, bristly hair or beard 20g；
(2) Fructus Crataegi is put into and fry with high heat in pot to black, take out cool cold standby；
(3) raw Semen Cassiae is put into parching to brown in processing machine and, to savory, take out cool cold standby；；
(4) remaining 5 taste medicine is cleaned and remove impurity, dry for standby；
(5) by after the above-mentioned 7 taste medicine mixing processing, pulverized 120 mesh sieves, after sterilizing, obtained final product.
Embodiment 3:
A kind of preparation method of the medicine treating hypertension, hyperlipidemia, comprises the steps:
(1) weigh: flower of Radix Notoginseng 25g, Semen Cassiae 12g, Radix seu Herba Gei aleppici 30g, Rhizoma Coptidis (processed) 13g, Fructus Evodiae 28g, Radix Uncariae rhynchophyllae 12g, Jiaoshan Hill
Short, bristly hair or beard 25g；
(2) Fructus Crataegi is put into and fry with high heat in pot to black, take out cool cold standby；
(3) raw Semen Cassiae is put into parching to brown in processing machine and, to savory, take out cool cold standby；；
(4) remaining 5 taste medicine is cleaned and remove impurity, dry for standby；
(5) by after the above-mentioned 7 taste medicine mixing processing, pulverized 140 mesh sieves, after sterilizing, obtained final product.
The above, be only presently preferred embodiments of the present invention, not the present invention is made with any pro forma restriction, appoints
What any is simply repaiied according to what the technical spirit of the present invention made to above example without departing from technical solution of the present invention content
Change, equivalent variations and modification, all still fall within the range of technical solution of the present invention.
Claims (3)
1. a kind of medicine treating hypertension, hyperlipidemia, by weight, including following raw material:
Flower of Radix Notoginseng 12-25 part, Semen Cassiae 12-28 part, Radix seu Herba Gei aleppici 13-30 part, Rhizoma Coptidis (processed) 13-32 part, Fructus Evodiae 11-28 part, hook
Rattan root 12-28 part, Fructus Crataegi (parched to brown) 15-25 part.
2. treatment hypertension according to claim 1, the medicine of hyperlipidemia, by weight, including following raw material:
12 parts of flower of Radix Notoginseng, 15 parts of Semen Cassiae, 13 parts of Radix seu Herba Gei aleppici, 13 parts of Rhizoma Coptidis (processed), 11 parts of Fructus Evodiae, 15 parts of Radix Uncariae rhynchophyllae, Fructus Crataegi (parched to brown)
15 parts.
3. treatment hypertension according to claim 1 and 2, the preparation method of the medicine of hyperlipidemia, comprise the steps:
(1) sample by weight；
(2) Fructus Crataegi is put into and fry with high heat in pot to black, take out cool cold standby；
(3) raw Semen Cassiae is put into parching to brown in processing machine and, to savory, take out cool cold standby；
(4) remaining 5 taste medicine is cleaned and remove impurity, dry for standby；
(5), after the above-mentioned 7 taste medicines processing being mixed by weight, pulverized 100-140 mesh sieve, after sterilizing, obtained final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610955700.5A CN106344694A (en) | 2016-10-26 | 2016-10-26 | Medicine for treating hypertension and hyperlipidemia and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610955700.5A CN106344694A (en) | 2016-10-26 | 2016-10-26 | Medicine for treating hypertension and hyperlipidemia and preparation method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN106344694A true CN106344694A (en) | 2017-01-25 |
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ID=57864329
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| Application Number | Title | Priority Date | Filing Date |
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| CN201610955700.5A Pending CN106344694A (en) | 2016-10-26 | 2016-10-26 | Medicine for treating hypertension and hyperlipidemia and preparation method thereof |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101804167A (en) * | 2010-05-21 | 2010-08-18 | 杨贞利 | Chinese drug for calming endopathic wind and reducing blood pressure and preparation method thereof |
| CN102343023A (en) * | 2011-10-18 | 2012-02-08 | 泽中卡 | Medicinal composition and preparation method and application thereof |
| CN103800822A (en) * | 2014-01-16 | 2014-05-21 | 唐咏春 | Traditional Chinese medicinal composition for treating hypertensive cerebral hemorrhage |
| CN104547669A (en) * | 2014-12-20 | 2015-04-29 | 熊安富 | Medicine for treating hypertension and preparation method thereof |
| CN104645057A (en) * | 2015-03-13 | 2015-05-27 | 青岛云天生物技术有限公司 | Traditional Chinese medicine composition for treating pulmonary hypertension and preparation method of traditional Chinese medicine composition |
| CN105396009A (en) * | 2015-11-26 | 2016-03-16 | 李�杰 | Semen torreyae combined medicine for treating pertussis |
-
2016
- 2016-10-26 CN CN201610955700.5A patent/CN106344694A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101804167A (en) * | 2010-05-21 | 2010-08-18 | 杨贞利 | Chinese drug for calming endopathic wind and reducing blood pressure and preparation method thereof |
| CN102343023A (en) * | 2011-10-18 | 2012-02-08 | 泽中卡 | Medicinal composition and preparation method and application thereof |
| CN103800822A (en) * | 2014-01-16 | 2014-05-21 | 唐咏春 | Traditional Chinese medicinal composition for treating hypertensive cerebral hemorrhage |
| CN104547669A (en) * | 2014-12-20 | 2015-04-29 | 熊安富 | Medicine for treating hypertension and preparation method thereof |
| CN104645057A (en) * | 2015-03-13 | 2015-05-27 | 青岛云天生物技术有限公司 | Traditional Chinese medicine composition for treating pulmonary hypertension and preparation method of traditional Chinese medicine composition |
| CN105396009A (en) * | 2015-11-26 | 2016-03-16 | 李�杰 | Semen torreyae combined medicine for treating pertussis |
Non-Patent Citations (2)
| Title |
|---|
| 谢东浩等: "《常用治疗肿瘤中药》", 31 October 2015 * |
| 阎洪琪: "《类风湿名医名方荟萃》", 31 December 1992 * |
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Application publication date: 20170125 |
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